|
US4044126A
(en)
|
1972-04-20 |
1977-08-23 |
Allen & Hanburys Limited |
Steroidal aerosol compositions and process for the preparation thereof
|
|
GB1429184A
(en)
|
1972-04-20 |
1976-03-24 |
Allen & Hanburys Ltd |
Physically anti-inflammatory steroids for use in aerosols
|
|
US4444887A
(en)
|
1979-12-10 |
1984-04-24 |
Sloan-Kettering Institute |
Process for making human antibody producing B-lymphocytes
|
|
US4716111A
(en)
|
1982-08-11 |
1987-12-29 |
Trustees Of Boston University |
Process for producing human antibodies
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
|
JP2532858B2
(ja)
|
1985-04-01 |
1996-09-11 |
セルテツク リミテツド |
形質転換したミエロ―マ細胞系
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US5869620A
(en)
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
|
ATE151110T1
(de)
|
1988-09-02 |
1997-04-15 |
Protein Eng Corp |
Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5413923A
(en)
|
1989-07-25 |
1995-05-09 |
Cell Genesys, Inc. |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
US5585112A
(en)
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
|
AU7247191A
(en)
|
1990-01-11 |
1991-08-05 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
|
WO1996033735A1
(en)
|
1995-04-27 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
CA2050918A1
(en)
|
1990-01-12 |
1991-07-13 |
Raju Kucherlapati |
Generation of xenogeneic antibodies
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
IT1246382B
(it)
|
1990-04-17 |
1994-11-18 |
Eurand Int |
Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
DE69133476T2
(de)
|
1990-08-29 |
2006-01-05 |
GenPharm International, Inc., Palo Alto |
Transgene Mäuse fähig zur Produktion heterologer Antikörper
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
|
US5543390A
(en)
|
1990-11-01 |
1996-08-06 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University |
Covalent microparticle-drug conjugates for biological targeting
|
|
EP0564531B1
(en)
|
1990-12-03 |
1998-03-25 |
Genentech, Inc. |
Enrichment method for variant proteins with altered binding properties
|
|
DK1471142T3
(da)
|
1991-04-10 |
2009-03-09 |
Scripps Research Inst |
Heterodimere receptor-biblioteker under anvendelse af fagemider
|
|
EP0519596B1
(en)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
A method for reducing the immunogenicity of antibody variable domains
|
|
WO1992022324A1
(en)
|
1991-06-14 |
1992-12-23 |
Xoma Corporation |
Microbially-produced antibody fragments and their conjugates
|
|
AU675916B2
(en)
|
1991-06-14 |
1997-02-27 |
Genentech Inc. |
Method for making humanized antibodies
|
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
|
US5851795A
(en)
|
1991-06-27 |
1998-12-22 |
Bristol-Myers Squibb Company |
Soluble CTLA4 molecules and uses thereof
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
ATE408012T1
(de)
|
1991-12-02 |
2008-09-15 |
Medical Res Council |
Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
|
|
CA2103887C
(en)
|
1991-12-13 |
2005-08-30 |
Gary M. Studnicka |
Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
|
|
GB9203459D0
(en)
|
1992-02-19 |
1992-04-08 |
Scotgen Ltd |
Antibodies with germ-line variable regions
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US6174666B1
(en)
|
1992-03-27 |
2001-01-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method of eliminating inhibitory/instability regions from mRNA
|
|
US6010715A
(en)
|
1992-04-01 |
2000-01-04 |
Bertek, Inc. |
Transdermal patch incorporating a polymer film incorporated with an active agent
|
|
US6024975A
(en)
|
1992-04-08 |
2000-02-15 |
Americare International Diagnostics, Inc. |
Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
|
|
ATE203767T1
(de)
|
1992-08-21 |
2001-08-15 |
Univ Bruxelles |
Immunoglobuline ohne leichte ketten
|
|
US6005079A
(en)
|
1992-08-21 |
1999-12-21 |
Vrije Universiteit Brussels |
Immunoglobulins devoid of light chains
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
DE69329974T2
(de)
|
1992-12-04 |
2001-07-19 |
Medical Research Council, London |
Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
|
|
US6274552B1
(en)
|
1993-03-18 |
2001-08-14 |
Cytimmune Sciences, Inc. |
Composition and method for delivery of biologically-active factors
|
|
US5985307A
(en)
|
1993-04-14 |
1999-11-16 |
Emory University |
Device and method for non-occlusive localized drug delivery
|
|
US5523092A
(en)
|
1993-04-14 |
1996-06-04 |
Emory University |
Device for local drug delivery and methods for using the same
|
|
ATE204325T1
(de)
|
1993-04-29 |
2001-09-15 |
Unilever Nv |
Herstellung von antikörpern oder funktionstüchtig gemachten teilen davon, abgeleitet von schweren ketten von immunglobulinen von camelidae
|
|
US6004534A
(en)
|
1993-07-23 |
1999-12-21 |
Massachusetts Institute Of Technology |
Targeted polymerized liposomes for improved drug delivery
|
|
WO1995015982A2
(en)
|
1993-12-08 |
1995-06-15 |
Genzyme Corporation |
Process for generating specific antibodies
|
|
US5997873A
(en)
|
1994-01-13 |
1999-12-07 |
Mount Sinai School Of Medicine Of The City University Of New York |
Method of preparation of heat shock protein 70-peptide complexes
|
|
EP1231268B1
(en)
|
1994-01-31 |
2005-07-27 |
Trustees Of Boston University |
Polyclonal antibody libraries
|
|
US6719972B1
(en)
|
1994-06-03 |
2004-04-13 |
Repligen Corporation |
Methods of inhibiting T cell proliferation or IL-2 accumulation with CTLA4- specific antibodies
|
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
|
US5759542A
(en)
|
1994-08-05 |
1998-06-02 |
New England Deaconess Hospital Corporation |
Compositions and methods for the delivery of drugs by platelets for the treatment of cardiovascular and other diseases
|
|
US5660854A
(en)
|
1994-11-28 |
1997-08-26 |
Haynes; Duncan H |
Drug releasing surgical implant or dressing material
|
|
US5983134A
(en)
|
1995-04-23 |
1999-11-09 |
Electromagnetic Bracing Systems Inc. |
Electrophoretic cuff apparatus drug delivery system
|
|
CA2219486A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6316652B1
(en)
|
1995-06-06 |
2001-11-13 |
Kosta Steliou |
Drug mitochondrial targeting agents
|
|
US5811097A
(en)
|
1995-07-25 |
1998-09-22 |
The Regents Of The University Of California |
Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling
|
|
US6167301A
(en)
|
1995-08-29 |
2000-12-26 |
Flower; Ronald J. |
Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
|
|
US5935576A
(en)
|
1995-09-13 |
1999-08-10 |
Fordham University |
Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens
|
|
GB9601081D0
(en)
|
1995-10-06 |
1996-03-20 |
Cambridge Antibody Tech |
Specific binding members for human transforming growth factor beta;materials and methods
|
|
US5989830A
(en)
|
1995-10-16 |
1999-11-23 |
Unilever Patent Holdings Bv |
Bifunctional or bivalent antibody fragment analogue
|
|
US6039975A
(en)
|
1995-10-17 |
2000-03-21 |
Hoffman-La Roche Inc. |
Colon targeted delivery system
|
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
|
TW345603B
(en)
|
1996-05-29 |
1998-11-21 |
Gmundner Fertigteile Gmbh |
A noise control device for tracks
|
|
US6027947A
(en)
|
1996-08-20 |
2000-02-22 |
Ramtron International Corporation |
Partially or completely encapsulated top electrode of a ferroelectric capacitor
|
|
US5985317A
(en)
|
1996-09-06 |
1999-11-16 |
Theratech, Inc. |
Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
|
|
NZ334914A
(en)
|
1996-10-01 |
2000-09-29 |
Stanford Res Inst Int |
Taste-masked microcapsule compositions and methods of manufacture using a phase seperation-coacervation technique
|
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
|
US6131570A
(en)
|
1998-06-30 |
2000-10-17 |
Aradigm Corporation |
Temperature controlling device for aerosol drug delivery
|
|
DK1500329T3
(da)
|
1996-12-03 |
2012-07-09 |
Amgen Fremont Inc |
Humane antistoffer, der specifikt binder TNF-alfa
|
|
US20060034844A1
(en)
|
1996-12-04 |
2006-02-16 |
The Regents Of The University Of California |
Stimulation of T cells against self antigens using CTLA-4 blocking agents
|
|
US5860957A
(en)
|
1997-02-07 |
1999-01-19 |
Sarcos, Inc. |
Multipathway electronically-controlled drug delivery system
|
|
US6017540A
(en)
|
1997-02-07 |
2000-01-25 |
Fordham University |
Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
|
|
AU6703198A
(en)
|
1997-03-21 |
1998-10-20 |
Brigham And Women's Hospital |
Immunotherapeutic ctla-4 binding peptides
|
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
|
WO1998046645A2
(en)
|
1997-04-14 |
1998-10-22 |
Micromet Gesellschaft Für Biomedizinische Forschung Mbh |
Method for the production of antihuman antigen receptors and uses thereof
|
|
US6060082A
(en)
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
|
US7951917B1
(en)
|
1997-05-02 |
2011-05-31 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US5948433A
(en)
|
1997-08-21 |
1999-09-07 |
Bertek, Inc. |
Transdermal patch
|
|
WO1999021537A1
(fr)
|
1997-10-28 |
1999-05-06 |
Bando Chemical Industries, Ltd. |
Feuille de timbre cutane et procede de production d'une feuille de base pour timbre
|
|
US5948646A
(en)
|
1997-12-11 |
1999-09-07 |
Fordham University |
Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes
|
|
WO1999047558A2
(en)
|
1998-03-19 |
1999-09-23 |
Heska Corporation |
T cell costimulatory proteins, sequences and uses thereof
|
|
US6048736A
(en)
|
1998-04-29 |
2000-04-11 |
Kosak; Kenneth M. |
Cyclodextrin polymers for carrying and releasing drugs
|
|
PT1137436E
(pt)
|
1998-12-03 |
2008-09-15 |
Univ California |
Estimulação das células t contra auto-antigénios por meio de agentes bloqueadores de ctla-4
|
|
US6682736B1
(en)
|
1998-12-23 |
2004-01-27 |
Abgenix, Inc. |
Human monoclonal antibodies to CTLA-4
|
|
US6271359B1
(en)
|
1999-04-14 |
2001-08-07 |
Musc Foundation For Research Development |
Tissue-specific and pathogen-specific toxic agents and ribozymes
|
|
US6256533B1
(en)
|
1999-06-09 |
2001-07-03 |
The Procter & Gamble Company |
Apparatus and method for using an intracutaneous microneedle array
|
|
PT1210428E
(pt)
|
1999-08-23 |
2015-07-21 |
Genetics Inst Llc |
Pd-1, um recetor para b7-4 e suas utilizações
|
|
US7605238B2
(en)
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
DK1212422T3
(da)
|
1999-08-24 |
2007-07-02 |
Medarex Inc |
Humane CTLA-4-antistoffer og anvendelserne deraf
|
|
DK1233987T3
(da)
|
1999-11-29 |
2009-09-28 |
Bac Ip B V |
Immobiliserede enkelt-domæne antigenbindende molekyler
|
|
AU784634B2
(en)
|
1999-11-30 |
2006-05-18 |
Mayo Foundation For Medical Education And Research |
B7-H1, a novel immunoregulatory molecule
|
|
EP1261376A1
(en)
|
2000-01-27 |
2002-12-04 |
Genetics Institute, LLC |
Antibodies against ctla4(cd152), conjugates comprising same, and uses thereof
|
|
US6261595B1
(en)
|
2000-02-29 |
2001-07-17 |
Zars, Inc. |
Transdermal drug patch with attached pocket for controlled heating device
|
|
EP1274733A1
(en)
|
2000-04-12 |
2003-01-15 |
Genetics Institute, Inc. |
Surface-bound antigen binding portions of antibodies that bind to ctla-4 and cd28 and uses therefor
|
|
US7041870B2
(en)
*
|
2000-11-30 |
2006-05-09 |
Medarex, Inc. |
Transgenic transchromosomal rodents for making human antibodies
|
|
IL149701A0
(en)
|
2001-05-23 |
2002-11-10 |
Pfizer Prod Inc |
Use of anti-ctla-4 antibodies
|
|
EP2298809A3
(en)
|
2001-07-12 |
2012-02-15 |
FOOTE, Jefferson |
Super humanized antibodies
|
|
CA2466279A1
(en)
|
2001-11-13 |
2003-05-22 |
Dana-Farber Cancer Institute, Inc. |
Agents that modulate immune cell activation and methods of use thereof
|
|
AUPS054702A0
(en)
|
2002-02-14 |
2002-03-07 |
Immunaid Pty Ltd |
Cancer therapy
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
US20040014194A1
(en)
|
2002-03-27 |
2004-01-22 |
Schering Corporation |
Beta-secretase crystals and methods for preparing and using the same
|
|
AU2003234736B2
(en)
|
2002-04-12 |
2008-09-25 |
E. R. Squibb & Sons, L.L.C. |
Methods of treatment using CTLA-4 antibodies
|
|
US20060093612A1
(en)
|
2002-05-02 |
2006-05-04 |
Srivastava Pramod K |
Use of heat shock proteins to enhance efficacy of antibody therapeutics
|
|
IL149820A0
(en)
|
2002-05-23 |
2002-11-10 |
Curetech Ltd |
Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
|
|
ATE481985T1
(de)
|
2002-07-03 |
2010-10-15 |
Ono Pharmaceutical Co |
Immunpotenzierende zusammensetzungen
|
|
WO2004029069A2
(en)
|
2002-09-30 |
2004-04-08 |
Pfizer Products Inc. |
Hybridomas producing high levels of human sequence antibody
|
|
CA2508660C
(en)
|
2002-12-23 |
2013-08-20 |
Wyeth |
Antibodies against pd-1 and uses therefor
|
|
US9068234B2
(en)
|
2003-01-21 |
2015-06-30 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating gene expression
|
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
|
US7465446B2
(en)
|
2003-05-30 |
2008-12-16 |
Medarex, Inc. |
Surrogate therapeutic endpoint for anti-CTLA4-based immunotherapy of disease
|
|
EP1660534A2
(en)
|
2003-08-22 |
2006-05-31 |
MedImmune, Inc. |
Humanization of antibodies
|
|
WO2005092380A2
(en)
|
2004-03-26 |
2005-10-06 |
Pfizer Products Inc |
Uses of anti-ctla-4 antibodies
|
|
US7494779B2
(en)
|
2004-06-14 |
2009-02-24 |
Li-Te Chin |
Method for producing human antibodies to human CD152 with properties of agonist, antagonist, or inverse agonist
|
|
US20060057626A1
(en)
|
2004-09-03 |
2006-03-16 |
Nichol Geoffrey M |
Assessment of CTLA-4 polymorphisms in CTLA-4 blockade therapy
|
|
WO2006029219A2
(en)
|
2004-09-08 |
2006-03-16 |
Ohio State University Research Foundation |
Human monoclonal anti-ctla4 antibodies in cancer treatment
|
|
DE102004063494A1
(de)
|
2004-12-23 |
2006-07-13 |
Tegenero Ag |
Antikörper
|
|
TW200719913A
(en)
|
2005-03-08 |
2007-06-01 |
Pharmacia & Upjohn Co Llc |
Anti-madcam antibody compositions
|
|
US20060240006A1
(en)
|
2005-04-20 |
2006-10-26 |
Chishih Chu |
Novel antibody structures derived from human germline sequences
|
|
KR101498834B1
(ko)
|
2005-05-09 |
2015-03-05 |
오노 야꾸힝 고교 가부시키가이샤 |
예정 사멸 인자 1(pd-1)에 대한 인간 모노클로날 항체, 및 항-pd-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법
|
|
JP2006327937A
(ja)
|
2005-05-23 |
2006-12-07 |
Ritsutoku Kin |
ヒト胚細胞系遺伝子構造を具えたヒト抗体構造及びその誘導フラグメント
|
|
PL2397156T3
(pl)
|
2005-06-08 |
2017-07-31 |
Dana-Farber Cancer Institute, Inc. |
Sposoby i kompozycje do leczenia uporczywych infekcji i nowotworu poprzez hamowanie ścieżki zaprogramowanej śmierci komórki 1 (PD-1)
|
|
HRP20080053A2
(hr)
|
2005-07-01 |
2009-08-31 |
Medarex |
Ljudska monoklonska protutijela na ligand 1 za programiranu smrt stanice (pd-l1)
|
|
WO2007056539A2
(en)
|
2005-11-08 |
2007-05-18 |
Medarex, Inc. |
Prophylaxis and treatment of enterocolitis associated with anti-ctla-4 antibody therapy
|
|
JP2009518446A
(ja)
|
2005-12-07 |
2009-05-07 |
メダレックス インコーポレーティッド |
Ctla−4抗体投与量漸増レジメン
|
|
EA014232B1
(ru)
|
2005-12-20 |
2010-10-29 |
Бристол-Маерс Сквибб Компани |
Стабильные белковые препараты
|
|
JP6092497B2
(ja)
|
2006-03-30 |
2017-03-08 |
ユニバーシティー オブ カリフォルニア |
抗ctla−4抗体の限局性分泌のための方法および組成物
|
|
US7919079B2
(en)
|
2006-03-31 |
2011-04-05 |
Biosante Pharmaceuticals, Inc. |
Cancer immunotherapy compositions and methods of use
|
|
CA2647282A1
(en)
|
2006-04-05 |
2007-10-11 |
Pfizer Products Inc. |
Ctla4 antibody combination therapy
|
|
CN101074264B
(zh)
|
2006-05-17 |
2011-08-17 |
上海抗体药物国家工程研究中心有限公司 |
一种重组抗ctla4单克隆抗体及其制备方法和用途
|
|
AU2007331672A1
(en)
|
2006-12-15 |
2008-06-19 |
Ablynx N.V. |
Amino acid sequences that modulate the interaction between cells of the immune system
|
|
WO2008100562A2
(en)
|
2007-02-14 |
2008-08-21 |
Medical College Of Georgia Research Institute, Inc. |
Indoleamine 2,3-dioxygenase, pd-1/pd-l pathways, and ctla4 pathways in the activation of regulatory t cells
|
|
US9244059B2
(en)
|
2007-04-30 |
2016-01-26 |
Immutep Parc Club Orsay |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
|
CN104945508B
(zh)
|
2007-06-18 |
2019-02-22 |
默沙东有限责任公司 |
针对人程序性死亡受体pd-1的抗体
|
|
CN101801413A
(zh)
|
2007-07-12 |
2010-08-11 |
托勒克斯股份有限公司 |
采用gitr结合分子的联合疗法
|
|
PE20140196A1
(es)
|
2007-08-09 |
2014-03-19 |
Boehringer Ingelheim Int |
Anticuerpos anti-cd37
|
|
JP6035009B2
(ja)
|
2007-08-22 |
2016-11-30 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
活性化可能な結合ポリペプチドおよびその同定方法ならびに使用
|
|
US7968300B2
(en)
|
2007-11-21 |
2011-06-28 |
Li-Te Chin |
Method of isolating regulatory T cells from human samples
|
|
US8227577B2
(en)
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
|
ES2558568T3
(es)
|
2008-01-08 |
2016-02-05 |
Bristol-Myers Squibb Company |
Combinación de anticuerpo anti-CTLA4 con agentes moduladores de la tubulina para el tratamiento de enfermedades proliferativas
|
|
WO2009100140A1
(en)
*
|
2008-02-04 |
2009-08-13 |
Medarex, Inc. |
Anti-clta-4 antibodies with reduced blocking of binding of ctla-4 to b7 and uses thereof
|
|
CN104548091A
(zh)
|
2008-02-11 |
2015-04-29 |
治疗科技公司 |
用于肿瘤治疗的单克隆抗体
|
|
US8168757B2
(en)
|
2008-03-12 |
2012-05-01 |
Merck Sharp & Dohme Corp. |
PD-1 binding proteins
|
|
KR101847107B1
(ko)
|
2008-07-08 |
2018-04-10 |
인사이트 홀딩스 코포레이션 |
인돌아민 2,3-디옥시게나아제의 억제제로서의 1,2,5-옥사디아졸
|
|
US8119129B2
(en)
|
2008-08-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Combination of anti-CTLA4 antibody with dasatinib for the treatment of proliferative diseases
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
JP5798919B2
(ja)
|
2008-08-25 |
2015-10-21 |
アンプリミューン、インコーポレーテッドAmplimmune, Inc. |
Pd−1アンタゴニストの組成物および使用方法
|
|
WO2010029435A1
(en)
|
2008-09-12 |
2010-03-18 |
Isis Innovation Limited |
Pd-1 specific antibodies and uses thereof
|
|
EP3133086B1
(en)
|
2008-09-26 |
2018-08-01 |
Dana-Farber Cancer Institute, Inc. |
Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses thereof
|
|
CA3120172A1
(en)
|
2008-12-09 |
2010-07-08 |
Genentech, Inc. |
Anti-pd-l1 antibodies and their use to enhance t-cell function
|
|
BRPI1006141B8
(pt)
|
2009-01-12 |
2021-05-25 |
Cytomx Therapeutics Llc |
composições de anticorpo modificado, métodos para preparar e usar as mesmas
|
|
GB0903325D0
(en)
|
2009-02-26 |
2009-04-08 |
Univ Aberdeen |
Antibody molecules
|
|
KR102010827B1
(ko)
|
2009-06-26 |
2019-08-14 |
리제너론 파마슈티칼스 인코포레이티드 |
천연 면역글로불린 포맷을 가지는 용이하게 분리된 이중특이성 항체
|
|
SMT201700293T1
(it)
*
|
2009-07-20 |
2017-07-18 |
Bristol Myers Squibb Co |
Combinazione di un anticorpo anti-ctla-4 con etoposide per il trattamento sinergico di malattie proliferative
|
|
CA2769822C
(en)
|
2009-08-13 |
2019-02-19 |
The Johns Hopkins University |
Methods of modulating immune function
|
|
EP2488553B1
(en)
|
2009-10-12 |
2015-06-17 |
Pfizer Inc. |
Cancer treatment
|
|
GB0920258D0
(en)
|
2009-11-19 |
2010-01-06 |
Alligator Bioscience Ab |
New medical agents and use thereof
|
|
HUE037159T2
(hu)
|
2009-11-24 |
2018-08-28 |
Medimmune Ltd |
Targetált kötõdõ ágensek B7-H1 ellen
|
|
CN102134276A
(zh)
|
2010-01-22 |
2011-07-27 |
上海抗体药物国家工程研究中心有限公司 |
一种抗ctla-4嵌合抗体
|
|
WO2011100841A1
(en)
|
2010-02-16 |
2011-08-25 |
Valorisation-Recherche, Limited Partnership |
Pd-1 modulation and uses thereof for modulating hiv replication
|
|
US8993731B2
(en)
|
2010-03-11 |
2015-03-31 |
Ucb Biopharma Sprl |
PD-1 antibody
|
|
WO2011120134A1
(en)
|
2010-03-29 |
2011-10-06 |
Zymeworks, Inc. |
Antibodies with enhanced or suppressed effector function
|
|
GB201103955D0
(en)
|
2011-03-09 |
2011-04-20 |
Antitope Ltd |
Antibodies
|
|
EP3403672A1
(en)
|
2011-04-20 |
2018-11-21 |
Medlmmune, LLC |
Antibodies and other molecules that bind b7-h1 and pd-1
|
|
WO2012162277A1
(en)
*
|
2011-05-25 |
2012-11-29 |
Merck Sharp & Dohme Corp. |
METHOD FOR PREPARING Fc-CONTAINING POLYPEPTIDES HAVING IMPROVED PROPERTIES
|
|
EP2723381A4
(en)
|
2011-06-21 |
2015-03-18 |
Univ Johns Hopkins |
FOCUSED RADIATION FOR THE REINFORCEMENT OF IMMUNE TREATMENTS AGAINST NEOPLASMS
|
|
JP6240600B2
(ja)
|
2011-07-24 |
2017-11-29 |
キュアテク リミテッド |
ヒト化免疫モノクローナル抗体の変異体
|
|
ES2893855T3
(es)
|
2011-08-11 |
2022-02-10 |
Ono Pharmaceutical Co |
Agente terapéutico para enfermedades autoinmunes que comprende agonista de PD-1
|
|
US8920075B2
(en)
|
2011-09-01 |
2014-12-30 |
Halo Maritime Defense Systems, Inc. |
Marine barrier and gate
|
|
AU2013201121A1
(en)
|
2011-09-20 |
2013-04-04 |
Vical Incorporated |
Synergistic anti-tumor efficacy using alloantigen combination immunotherapy
|
|
MX349096B
(es)
|
2011-11-28 |
2017-07-11 |
Merck Patent Gmbh |
Anticuerpos anti-pd-l1 y sus usos.
|
|
JP2015509592A
(ja)
|
2012-02-23 |
2015-03-30 |
スローン − ケッタリング インスティチュート フォー キャンサー リサーチ |
免疫調節治療剤を用いた処置に対する反応性の予測及びこのような処置の間のアブスコパル効果をモニターする方法
|
|
US20150079100A1
(en)
|
2012-03-23 |
2015-03-19 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla-4 antibodies
|
|
KR20200075023A
(ko)
|
2012-05-04 |
2020-06-25 |
화이자 인코포레이티드 |
전립선 관련된 항원 및 백신 기재 면역치료 요법
|
|
WO2013169388A1
(en)
|
2012-05-08 |
2013-11-14 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Predictive biomarkers for ctla-4 blockade therapy and for pd-1 blockade therapy
|
|
WO2013173223A1
(en)
|
2012-05-15 |
2013-11-21 |
Bristol-Myers Squibb Company |
Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
|
|
AU2013267161A1
(en)
|
2012-05-31 |
2014-11-20 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind PD-L1
|
|
RU2015101803A
(ru)
|
2012-06-22 |
2016-08-20 |
Сайтомкс Терапьютикс, Инк. |
Перекрестно реактивные антитела к jagged 1/k jagged 2, активируемые антитела к jagged и способы их применения
|
|
US9856314B2
(en)
|
2012-06-22 |
2018-01-02 |
Cytomx Therapeutics, Inc. |
Activatable antibodies having non-binding steric moieties and methods of using the same
|
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
|
WO2014022758A1
(en)
|
2012-08-03 |
2014-02-06 |
Dana-Farber Cancer Institute, Inc. |
Single agent anti-pd-l1 and pd-l2 dual binding antibodies and methods of use
|
|
CN107892719B
(zh)
|
2012-10-04 |
2022-01-14 |
达纳-法伯癌症研究所公司 |
人单克隆抗-pd-l1抗体和使用方法
|
|
HK1213924A1
(zh)
|
2012-10-23 |
2016-07-15 |
Bristol-Myers Squibb Company |
用於治療癌症的抗kir和抗ctla-4抗體組合
|
|
US10034939B2
(en)
|
2012-10-26 |
2018-07-31 |
The University Of Chicago |
Synergistic combination of immunologic inhibitors for the treatment of cancer
|
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
|
AU2014204015A1
(en)
|
2013-01-04 |
2015-07-09 |
Cytomx Therapeutics, Inc. |
Compositions and methods for detecting protease activity in biological systems
|
|
WO2014144960A2
(en)
|
2013-03-15 |
2014-09-18 |
Abbvie Biotherapeutics Inc. |
Fc variants
|
|
KR101763352B1
(ko)
|
2013-03-15 |
2017-07-31 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
항lag3 결합 단백질
|
|
WO2014179491A2
(en)
|
2013-04-30 |
2014-11-06 |
La Jolla Institute For Allergy And Immunology |
MODULATION OF REGULATORY T CELL FUNCTION VIA PROTEIN KINASE C-η
|
|
ES2845609T3
(es)
|
2013-05-02 |
2021-07-27 |
Anaptysbio Inc |
Anticuerpos dirigidos contra muerte programada-1 (PD-1)
|
|
CA3175360C
(en)
|
2013-05-31 |
2024-05-28 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind pd-1
|
|
US20160145355A1
(en)
|
2013-06-24 |
2016-05-26 |
Biomed Valley Discoveries, Inc. |
Bispecific antibodies
|
|
CN104250302B
(zh)
|
2013-06-26 |
2017-11-14 |
上海君实生物医药科技股份有限公司 |
抗pd‑1抗体及其应用
|
|
MX384142B
(es)
|
2013-07-16 |
2025-03-14 |
Genentech Inc |
Antagonista de unión al eje pd-1 e inhibidores de tigit para usarse en el tratamiento de cáncer.
|
|
BR112016001420A2
(pt)
|
2013-08-02 |
2018-01-23 |
Aduro Biotech Holdings Europe B V |
combinação de agonistas de cd27 e inibição pontual imune para estimulação imune
|
|
BR112016003528A8
(pt)
|
2013-08-22 |
2018-01-30 |
Council Queensland Inst Medical Res |
modulação de receptor imuno para tratamento de câncer e infecções virais
|
|
US10966998B2
(en)
|
2013-09-05 |
2021-04-06 |
The Johns Hopkins University |
Cancer therapy via a combination of epigenetic modulation and immune modulation
|
|
US10077305B2
(en)
|
2013-09-10 |
2018-09-18 |
Medimmune Limited |
Antibodies against PD-1 and uses thereof
|
|
EA034666B1
(ru)
|
2013-09-13 |
2020-03-04 |
Бейджин Свитзерланд Гмбх |
Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела
|
|
KR20160055269A
(ko)
|
2013-09-20 |
2016-05-17 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하기 위한 항-lag-3 항체 및 항-pd-1 항체의 조합물
|
|
WO2015048312A1
(en)
|
2013-09-26 |
2015-04-02 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
JP6607850B2
(ja)
|
2013-10-18 |
2019-11-20 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
Vegfアンタゴニスト及び抗ctla−4抗体の組み合わせを含む方法及び組成物
|
|
CA2926856A1
(en)
|
2013-10-25 |
2015-04-30 |
Dana-Farber Cancer Institute, Inc. |
Anti-pd-l1 monoclonal antibodies and fragments thereof
|
|
CN104558177B
(zh)
|
2013-10-25 |
2020-02-18 |
苏州思坦维生物技术股份有限公司 |
拮抗抑制程序性死亡受体pd-1与其配体结合的单克隆抗体及其编码序列与用途
|
|
JP2016540042A
(ja)
|
2013-11-05 |
2016-12-22 |
コグネート バイオサービシズ, インコーポレイテッド |
がんを処置するためのチェックポイント阻害剤および治療薬の組合せ
|
|
SI3081576T1
(sl)
|
2013-12-12 |
2019-12-31 |
Shanghai Hengrui Pharmaceutical Co., Ltd., |
Protitelo PD-1, njegov antigen-vezavni fragment in njegova medicinska uporaba
|
|
PT3094351T
(pt)
|
2014-01-15 |
2022-02-22 |
Kadmon Corp Llc |
Agentes imunomoduladores
|
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
|
RS62788B1
(sr)
|
2014-01-28 |
2022-02-28 |
Bristol Myers Squibb Co |
Anti-lag-3 antitela za lečenje hematoloških maligniteta
|
|
NZ721364A
(en)
|
2014-02-10 |
2023-04-28 |
Merck Patent Gmbh |
Targeted tgfβ inhibition
|
|
WO2015134605A1
(en)
|
2014-03-05 |
2015-09-11 |
Bristol-Myers Squibb Company |
Treatment of renal cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
|
|
ES2770684T3
(es)
|
2014-03-14 |
2020-07-02 |
Novartis Ag |
Moléculas de anticuerpos contra LAG-3 y usos de los mismos
|
|
WO2015153820A1
(en)
|
2014-04-02 |
2015-10-08 |
Felder Mitchell S |
Ctla-4 blockade with metronomic chemotherapy for the treatment of cancer
|
|
CA2949121A1
(en)
|
2014-05-15 |
2015-11-19 |
Bristol-Myers Squibb Company |
Treatment of lung cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
|
|
EP3149042B1
(en)
|
2014-05-29 |
2019-08-28 |
Spring Bioscience Corporation |
Pd-l1 antibodies and uses thereof
|
|
WO2015195163A1
(en)
|
2014-06-20 |
2015-12-23 |
R-Pharm Overseas, Inc. |
Pd-l1 antagonist fully human antibody
|
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
|
KR102130600B1
(ko)
|
2014-07-03 |
2020-07-08 |
베이진 엘티디 |
Pd-l1 항체와 이를 이용한 치료 및 진단
|
|
JP6895374B2
(ja)
|
2014-07-16 |
2021-06-30 |
トランジェーヌTransgene |
免疫チェックポイントモジュレーターの発現用腫瘍溶解性ウイルス
|
|
CN105330740B
(zh)
|
2014-07-30 |
2018-08-17 |
珠海市丽珠单抗生物技术有限公司 |
抗pd-1抗体及其应用
|
|
CN105296433B
(zh)
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
|
AU2015298356B2
(en)
|
2014-08-05 |
2020-11-19 |
MabQuest SA |
Immunological reagents binding to pd-1
|
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
|
WO2016030455A1
(en)
|
2014-08-28 |
2016-03-03 |
Medimmune Limited |
Anti-b7-h1 and anti-ctla-4 antibodies for treating non-small lung cancer
|
|
MY193723A
(en)
|
2014-08-29 |
2022-10-27 |
Hoffmann La Roche |
Combination therapy of tumor-targeted il-2 variant immunocytokines and antibodies against human pd-l1
|
|
RU2718914C2
(ru)
|
2014-09-13 |
2020-04-15 |
Новартис Аг |
Сочетанные способы лечения с использованием ингибиторов alk
|
|
EP3200775B1
(en)
|
2014-10-03 |
2019-11-20 |
Novartis AG |
Combination therapies
|
|
US9988452B2
(en)
|
2014-10-14 |
2018-06-05 |
Novartis Ag |
Antibody molecules to PD-L1 and uses thereof
|
|
JP2018500384A
(ja)
|
2014-11-11 |
2018-01-11 |
メディミューン リミテッド |
腫瘍形成を治療するための治療の組合せ
|
|
KR20170080697A
(ko)
|
2014-11-13 |
2017-07-10 |
더 존스 홉킨스 유니버시티 |
관문 차단 및 미소부수체 불안정성
|
|
US20180133313A1
(en)
|
2014-12-16 |
2018-05-17 |
Bristol-Myers Squibb Company |
Use of immune checkpoint inhibitors in central nervous systems neoplasms
|
|
US20170340733A1
(en)
|
2014-12-19 |
2017-11-30 |
Novartis Ag |
Combination therapies
|
|
JP6797803B2
(ja)
|
2014-12-31 |
2020-12-09 |
セルジーン コーポレイション |
ナチュラルキラー細胞を用いて血液障害、固形腫瘍、又は感染性疾患を治療する方法
|
|
IL292578A
(en)
|
2015-02-13 |
2022-06-01 |
Sorrento Therapeutics Inc |
Antibody therapeutics that bind ctla4
|
|
WO2016149387A1
(en)
|
2015-03-18 |
2016-09-22 |
The Johns Hopkins University |
Androgen deprivation with immune checkpoint blockade delays the development of castration resistant prostate cancer
|
|
WO2016168809A1
(en)
|
2015-04-17 |
2016-10-20 |
Krishnan Nandabalan |
Compositions and methods for preventing tumor growth and treating cancer by targeting lectin galactoside-binding soluble 3 binding protein
|
|
WO2016179576A1
(en)
|
2015-05-07 |
2016-11-10 |
Bioxcel Corporation |
Novel immunomodulatory therapeutic strategies targeting tumors in cancer
|
|
US20180256715A1
(en)
|
2015-05-13 |
2018-09-13 |
The Board Of Regents Of The University Of Texas System |
Anti-ctla-4 blockade
|
|
US20160347848A1
(en)
|
2015-05-28 |
2016-12-01 |
Medimmune Limited |
Therapeutic combinations and methods for treating neoplasia
|
|
HRP20201031T1
(hr)
*
|
2015-05-29 |
2020-10-16 |
Agenus Inc. |
Anti-ctla-4 protutijela i postupci njihove upotrebe
|
|
WO2016196389A1
(en)
|
2015-05-29 |
2016-12-08 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
|
CN106714836A
(zh)
|
2015-06-05 |
2017-05-24 |
H·李·莫菲特癌症中心研究有限公司 |
Gm‑csf/cd40l疫苗和检查点抑制剂联合治疗
|
|
RS61532B1
(sr)
|
2015-07-14 |
2021-04-29 |
Bristol Myers Squibb Co |
Postupak lečenja kancera primenom inhibitora imunološke kontrolne tačke; antitelo koje se vezuje za receptor programirane smrti-1 (pd-1) ili ligand programirane smrti-1 (pd-l1)
|
|
WO2017021913A1
(en)
|
2015-08-04 |
2017-02-09 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
|
WO2017025871A1
(en)
|
2015-08-07 |
2017-02-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
|
WO2017062615A2
(en)
|
2015-10-08 |
2017-04-13 |
Macrogenics, Inc. |
Combination therapy for the treatment of cancer
|
|
WO2017079303A1
(en)
|
2015-11-02 |
2017-05-11 |
The Cleveland Clinic Foundation |
Sequentially orchestrated immune checkpoint therapy for the treatment and prevention of cancer
|
|
LT3389699T
(lt)
|
2015-12-15 |
2024-06-10 |
OncoC4, Inc. |
Chimeriniai ir humanizuoti monokloniniai antikūnai prieš žmogaus ctla4 ir jų panaudojimas
|
|
TWI808934B
(zh)
|
2015-12-31 |
2023-07-21 |
美商伯克利之光生命科技公司 |
經工程化以表現促發炎多肽之腫瘤浸潤細胞
|
|
US20190241658A1
(en)
|
2016-01-10 |
2019-08-08 |
Modernatx, Inc. |
Therapeutic mRNAs encoding anti CTLA-4 antibodies
|
|
ES2924775T3
(es)
|
2016-01-28 |
2022-10-10 |
Inst Nat Sante Rech Med |
Métodos y composición farmacéutica para el tratamiento del cáncer
|
|
US20170233476A1
(en)
|
2016-02-12 |
2017-08-17 |
Sorrento Therapeutics, Inc. |
Antibody Therapeutics That Bind CTLA4
|
|
EP3213768A1
(en)
|
2016-03-01 |
2017-09-06 |
LODOCO CLINICAL Kft |
Combination of low dose immune checkpoint blockade with high dose il-2 for treating metastatic cancer
|
|
LT3423087T
(lt)
|
2016-03-04 |
2024-01-25 |
Io Biotech Aps |
Kompleksinė priešvėžinė terapija
|
|
JP7208492B2
(ja)
|
2016-03-10 |
2023-01-19 |
シージー オンコロジー, インコーポレイテッド |
併用療法によって固形腫瘍又はリンパ系腫瘍を処置する方法
|
|
US20190077856A1
(en)
|
2016-03-15 |
2019-03-14 |
Memorial Sloan Kettering Cancer Center |
Method of treating diseases using kinase modulators
|
|
SG10201603721TA
(en)
|
2016-05-10 |
2017-12-28 |
Agency Science Tech & Res |
Anti-CTLA-4 Antibodies
|
|
CN107400166A
(zh)
|
2016-05-19 |
2017-11-28 |
苏州康宁杰瑞生物科技有限公司 |
针对ctla4的单域抗体及其衍生蛋白
|
|
CN109890387B
(zh)
|
2016-05-20 |
2022-06-14 |
拜尔哈文制药股份有限公司 |
谷氨酸调节剂与免疫疗法用以治疗癌症的用途
|
|
KR102523402B1
(ko)
|
2016-06-14 |
2023-04-19 |
젠코어 인코포레이티드 |
이중특이적 체크포인트 억제제 항체
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
AU2017373945B2
(en)
*
|
2016-12-07 |
2025-01-23 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
AU2017373944B2
(en)
*
|
2016-12-07 |
2022-02-03 |
Agenus Inc. |
Anti-CTLA-4 antibodies and methods of use thereof
|