MX2012009328A - Polipeptidos agonistas que se enlazan a dr5. - Google Patents
Polipeptidos agonistas que se enlazan a dr5.Info
- Publication number
- MX2012009328A MX2012009328A MX2012009328A MX2012009328A MX2012009328A MX 2012009328 A MX2012009328 A MX 2012009328A MX 2012009328 A MX2012009328 A MX 2012009328A MX 2012009328 A MX2012009328 A MX 2012009328A MX 2012009328 A MX2012009328 A MX 2012009328A
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- amino acid
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Health & Medical Sciences (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US30317310P | 2010-02-10 | 2010-02-10 | |
| US30859910P | 2010-02-26 | 2010-02-26 | |
| PCT/EP2011/051958 WO2011098520A1 (en) | 2010-02-10 | 2011-02-10 | Agonist dr5 binding polypeptides |
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| MX2012009328A true MX2012009328A (es) | 2012-11-30 |
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| MX2012009328A MX2012009328A (es) | 2010-02-10 | 2011-02-10 | Polipeptidos agonistas que se enlazan a dr5. |
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| GB201118359D0 (en) | 2011-10-25 | 2011-12-07 | Univ Sheffield | Pulmonary hypertension |
| MX350202B (es) * | 2012-03-28 | 2017-08-30 | Amgen Inc | Combinaciones de agonistas de receptores de muerte 5 (dr5). |
| PL2970473T3 (pl) | 2013-03-14 | 2018-01-31 | Bristol Myers Squibb Co | Kombinacja agonisty dr5 i antagonisty anty-pd-1 oraz metody stosowania |
| UA118028C2 (uk) | 2013-04-03 | 2018-11-12 | Рош Глікарт Аг | Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування |
| WO2015100409A2 (en) * | 2013-12-26 | 2015-07-02 | Tufts University | Methods, compositions and kits for treating a subject using a recombinant neutralizing binding protein |
| CA2936053A1 (en) | 2014-01-10 | 2015-07-16 | Teikyo Heisei University | Recombinant obligate anaerobic gram-positive bacteria |
| HK1247215A1 (zh) * | 2015-01-26 | 2018-09-21 | Macrogenics, Inc. | 包含dr5-结合结构域的多价分子 |
| CN104826121A (zh) * | 2015-02-11 | 2015-08-12 | 嘉兴学院 | 肿瘤靶向基因递送系统及其应用 |
| AU2016291701B2 (en) * | 2015-07-16 | 2022-09-29 | Inhibrx Biosciences, Inc. | Multivalent and multispecific DR5-binding fusion proteins |
| CN109195626B (zh) * | 2015-10-30 | 2022-09-13 | 银河生物技术有限责任公司 | 结合死亡受体4和死亡受体5的抗体 |
| NO2768984T3 (enExample) | 2015-11-12 | 2018-06-09 | ||
| KR101926834B1 (ko) | 2017-03-21 | 2018-12-07 | 동아에스티 주식회사 | 항-dr5 항체 및 그의 용도 |
| CA3082321A1 (en) * | 2017-11-13 | 2019-05-16 | Crescendo Biologics Limited | Single domain antibodies that bind to cd137 |
| US20190234933A1 (en) * | 2018-02-01 | 2019-08-01 | Genadam Therapeutics, Inc. | Compositions and assays |
| CN117285643A (zh) | 2022-06-16 | 2023-12-26 | 清华大学 | 一种相变调节套件及其用途 |
| PE20250669A1 (es) | 2022-07-15 | 2025-03-04 | Boehringer Ingelheim Int | Moleculas de union para el tratamiento del cancer |
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| CN120530143A (zh) * | 2023-01-17 | 2025-08-22 | 苏州永心生物科技有限公司 | Dr5结构域变体及其应用 |
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| WO2025206402A1 (ja) * | 2024-03-29 | 2025-10-02 | 株式会社沖縄Ｕｋａｍｉ養蚕 | アフリカ豚熱ワクチン産生組換えエリ蚕及びその利用 |
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- 2011-02-10 EP EP11702650A patent/EP2534176A1/en not_active Withdrawn
- 2011-02-10 TW TW100104511A patent/TWI480051B/zh active
- 2011-02-10 CA CA2789251A patent/CA2789251A1/en not_active Abandoned
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2012
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- 2012-08-02 IL IL221289A patent/IL221289A0/en unknown
- 2012-08-03 ZA ZA2012/05864A patent/ZA201205864B/en unknown
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- 2012-08-09 NI NI201200134A patent/NI201200134A/es unknown
- 2012-08-09 CL CL2012002217A patent/CL2012002217A1/es unknown
- 2012-08-10 CR CR20120415A patent/CR20120415A/es unknown
- 2012-08-10 CO CO12135218A patent/CO6561836A2/es unknown
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2014
- 2014-11-03 US US14/531,569 patent/US20150259426A1/en not_active Abandoned
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