|
GB699812A
(en)
|
1950-11-29 |
1953-11-18 |
British Ind Solvents Ltd |
Manufacture of substituted pyrimidones
|
|
GB1053063A
(https=)
*
|
1963-05-18 |
|
|
|
|
DE1670912C3
(de)
|
1967-08-18 |
1981-06-11 |
Bayer Ag, 5090 Leverkusen |
Herbizide Mittel auf Basis von 1,2,4-Triazin-5-onen
|
|
GB1377642A
(en)
|
1971-01-14 |
1974-12-18 |
Koninklijke Gist Spiritus |
Penicillanic and cephalosporanic acid derivatives
|
|
US3960949A
(en)
|
1971-04-02 |
1976-06-01 |
Schering Aktiengesellschaft |
1,2-Biguanides
|
|
DE2150686A1
(de)
|
1971-10-12 |
1973-04-19 |
Basf Ag |
6-amino-uracil-5-carbonsaeurethioamide
|
|
BE792206A
(https=)
|
1971-12-02 |
1973-06-01 |
Byk Gulden Lomberg Chem Fab |
|
|
GB1429184A
(en)
|
1972-04-20 |
1976-03-24 |
Allen & Hanburys Ltd |
Physically anti-inflammatory steroids for use in aerosols
|
|
US4044126A
(en)
|
1972-04-20 |
1977-08-23 |
Allen & Hanburys Limited |
Steroidal aerosol compositions and process for the preparation thereof
|
|
AU5996573A
(en)
|
1972-09-11 |
1975-03-06 |
Commonwealth Scientific And Industrial Research Organisation |
Pyridinium salts
|
|
US3823135A
(en)
|
1972-12-26 |
1974-07-09 |
Shell Oil Co |
Pyrimidone herbicides
|
|
GB1464248A
(en)
|
1973-11-01 |
1977-02-09 |
Ici Ltd |
Substituted triazinediones their preparation and use as herbicides
|
|
DE2361551A1
(de)
|
1973-12-11 |
1975-06-19 |
Basf Ag |
Wasserloesliche azofarbstoffe
|
|
DE2500024A1
(de)
|
1975-01-02 |
1976-07-08 |
Basf Ag |
Wasserloesliche azofarbstoffe
|
|
DE2720085A1
(de)
|
1977-05-05 |
1978-11-16 |
Hoechst Ag |
Pyrimido(6,1-a)isochinolin-2-on- derivate
|
|
US4494978A
(en)
*
|
1976-12-30 |
1985-01-22 |
Chevron Research Company |
Herbicidal N-(N'-hydrocarbyloxycarbamylalkyl)-2,6-dialkyl-alpha-haloacetanilides
|
|
CH657851A5
(de)
|
1983-06-28 |
1986-09-30 |
Ciba Geigy Ag |
Chromogene chinazolonverbindungen.
|
|
AR240698A1
(es)
|
1985-01-19 |
1990-09-28 |
Takeda Chemical Industries Ltd |
Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
|
|
US5614492A
(en)
|
1986-05-05 |
1997-03-25 |
The General Hospital Corporation |
Insulinotropic hormone GLP-1 (7-36) and uses thereof
|
|
SG59988A1
(en)
|
1987-09-04 |
1999-02-22 |
Beecham Group Plc |
Substituted thiazolidinedione derivatives
|
|
US4935493A
(en)
|
1987-10-06 |
1990-06-19 |
E. I. Du Pont De Nemours And Company |
Protease inhibitors
|
|
WO1989010701A1
(fr)
|
1988-05-05 |
1989-11-16 |
Basf Aktiengesellschaft |
Produits a base de derives d'uracil pour stimuler la croissance et reduire la graisse chez les animaux
|
|
JPH0251150A
(ja)
|
1988-08-12 |
1990-02-21 |
Konica Corp |
新規なシアンカプラーを含有するハロゲン化銀写真感光材料
|
|
IL92915A0
(en)
|
1989-01-05 |
1990-09-17 |
Ciba Geigy Ag |
Certain pyrrolylphenyl-substituted hydroxamic acid derivatives
|
|
GB8900382D0
(en)
|
1989-01-09 |
1989-03-08 |
Janssen Pharmaceutica Nv |
2-aminopyrimidinone derivatives
|
|
US5433955A
(en)
|
1989-01-23 |
1995-07-18 |
Akzo N.V. |
Site specific in vivo activation of therapeutic drugs
|
|
IE63502B1
(en)
|
1989-04-21 |
1995-05-03 |
Zeneca Ltd |
Aminopyrimidine derivatives useful for treating cardiovascular disorders
|
|
ATE164852T1
(de)
|
1990-01-24 |
1998-04-15 |
Douglas I Buckley |
Glp-1-analoga verwendbar in der diabetesbehandlung
|
|
CA2075627A1
(en)
|
1990-02-13 |
1991-08-14 |
William J. Greenlee |
Angiotensin ii antagonists incorporating a substituted benzyl element
|
|
US5814460A
(en)
|
1990-02-14 |
1998-09-29 |
Diatide, Inc. |
Method for generating and screening useful peptides
|
|
US5366862A
(en)
|
1990-02-14 |
1994-11-22 |
Receptor Laboratories, Inc. |
Method for generating and screening useful peptides
|
|
US5162326A
(en)
|
1990-02-15 |
1992-11-10 |
Takeda Chemical Industries, Ltd. |
Pyrimidinedione derivatives, their production and use
|
|
US5462928A
(en)
|
1990-04-14 |
1995-10-31 |
New England Medical Center Hospitals, Inc. |
Inhibitors of dipeptidyl-aminopeptidase type IV
|
|
DE4110019C2
(de)
|
1991-03-27 |
2000-04-13 |
Merck Patent Gmbh |
Imidazopyridine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
|
|
US5387512A
(en)
|
1991-06-07 |
1995-02-07 |
Merck & Co. Inc. |
Preparation of 3-[z-benzoxazol-2-yl)ethyl]-5-(1-hydroxyethyl)-6-methyl-2-(1H)-pyridinone by biotransformation
|
|
ES2153831T3
(es)
|
1991-10-22 |
2001-03-16 |
New England Medical Center Inc |
Inhibidores de dipeptidil-aminopeptidasa de tipo iv.
|
|
US6825169B1
(en)
|
1991-10-22 |
2004-11-30 |
Trustees Of Tufts College |
Inhibitors of dipeptidyl-aminopeptidase type IV
|
|
KR100236806B1
(ko)
|
1991-12-10 |
2000-01-15 |
시오노 요시히코 |
방향족 설폰아미드계 하이드록삼산 유도체
|
|
US5350752A
(en)
|
1991-12-16 |
1994-09-27 |
E. R. Squibb & Sons, Inc. |
Dihydropyrimidine derivatives
|
|
DE4141788A1
(de)
|
1991-12-18 |
1993-06-24 |
Merck Patent Gmbh |
Imidazopyridine
|
|
US5602102A
(en)
|
1992-05-29 |
1997-02-11 |
Board Of Regents, The Univ. Of Tx System |
Dipeptidyl peptidase-I inhibitors and uses thereof
|
|
DE4305602A1
(de)
|
1992-06-17 |
1993-12-23 |
Merck Patent Gmbh |
Imidazopyridine
|
|
AU4794393A
(en)
|
1992-07-31 |
1994-03-03 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Producing increased numbers of hematopoietic cells by administering inhibitors of dipeptidyl peptidase iv
|
|
EP0915090A1
(en)
|
1992-09-10 |
1999-05-12 |
Eli Lilly And Company |
Compounds useful as hypoglycemic agents and for treating Alzheimer's disease
|
|
IL106998A0
(en)
*
|
1992-09-17 |
1993-12-28 |
Univ Florida |
Brain-enhanced delivery of neuroactive peptides by sequential metabolism
|
|
US5811281A
(en)
|
1993-07-12 |
1998-09-22 |
Cornell Research Foundation, Inc. |
Immortalized intestinal epithelial cell lines
|
|
IL111785A0
(en)
|
1993-12-03 |
1995-01-24 |
Ferring Bv |
Dp-iv inhibitors and pharmaceutical compositions containing them
|
|
DE4341453A1
(de)
|
1993-12-06 |
1995-06-08 |
Merck Patent Gmbh |
Imidazopyridine
|
|
US5798344A
(en)
|
1994-03-08 |
1998-08-25 |
Otsuka Pharmaceutical Factory, Inc. |
Phosphonic ester derivatives of quinazolinones
|
|
US5580979A
(en)
|
1994-03-15 |
1996-12-03 |
Trustees Of Tufts University |
Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions
|
|
US5543396A
(en)
|
1994-04-28 |
1996-08-06 |
Georgia Tech Research Corp. |
Proline phosphonate derivatives
|
|
EP0764151A2
(en)
|
1994-06-10 |
1997-03-26 |
Universitaire Instelling Antwerpen |
Purification of serine protease and synthetic inhibitors thereof
|
|
JP4124481B2
(ja)
|
1994-06-17 |
2008-07-23 |
ラトローブ ユニバーシティ |
昆虫の生物学的制御
|
|
US5601986A
(en)
|
1994-07-14 |
1997-02-11 |
Amgen Inc. |
Assays and devices for the detection of extrahepatic biliary atresia
|
|
DE4432860A1
(de)
|
1994-09-15 |
1996-03-21 |
Merck Patent Gmbh |
Imidazopyridine
|
|
US5512549A
(en)
|
1994-10-18 |
1996-04-30 |
Eli Lilly And Company |
Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
|
|
AU692090B2
(en)
|
1995-04-13 |
1998-05-28 |
Taiho Pharmaceutical Co., Ltd. |
Novel 4,6-diarylpyrimidine derivatives and salts thereof
|
|
US5614379A
(en)
|
1995-04-26 |
1997-03-25 |
Eli Lilly And Company |
Process for preparing anti-obesity protein
|
|
US6265551B1
(en)
|
1995-06-01 |
2001-07-24 |
Dana-Farber Cancer Institute, Inc. |
Form of dipeptidylpeptidase IV (CD26) found in human serum, antibodies thereto, and uses thereof
|
|
US6325989B1
(en)
|
1995-06-01 |
2001-12-04 |
Dana-Farber Cancer Institute, Inc. |
Form of dipeptidylpeptidase IV (CD26) found in human serum
|
|
DK0748800T3
(da)
|
1995-06-09 |
2001-08-27 |
Hoffmann La Roche |
Pyrimidindion-, pyrimidintrion- og triazindionderivater som alfa-1-adrenergiske receptorantagonister
|
|
JPH0928376A
(ja)
|
1995-07-21 |
1997-02-04 |
Ajinomoto Co Inc |
新規ジペプチジルペプチダーゼｉｖとその製造方法
|
|
WO1997029776A1
(en)
|
1996-02-13 |
1997-08-21 |
G.D. Searle & Co. |
Combinations having immunosuppressive effects, containing cyclooxygenase-2-inhibitors and 5-lipoxygenase inhibitors
|
|
US20020006899A1
(en)
|
1998-10-06 |
2002-01-17 |
Pospisilik Andrew J. |
Use of dipeptidyl peptidase IV effectors for lowering blood pressure in mammals
|
|
DE19616486C5
(de)
|
1996-04-25 |
2016-06-30 |
Royalty Pharma Collection Trust |
Verfahren zur Senkung des Blutglukosespiegels in Säugern
|
|
US5965532A
(en)
|
1996-06-28 |
1999-10-12 |
Trustees Of Tufts College |
Multivalent compounds for crosslinking receptors and uses thereof
|
|
US5885997A
(en)
|
1996-07-01 |
1999-03-23 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
|
CZ298812B6
(cs)
|
1996-07-01 |
2008-02-13 |
Dr. Reddy's Laboratories Limited |
Azolidindionové deriváty, způsob jejich přípravy, farmaceutické kompozice s jejich obsahem a jejich použití v léčbě diabetu a příbuzných nemocí
|
|
US7235627B2
(en)
|
1996-08-30 |
2007-06-26 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
|
US6458924B2
(en)
|
1996-08-30 |
2002-10-01 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
|
US6006753A
(en)
|
1996-08-30 |
1999-12-28 |
Eli Lilly And Company |
Use of GLP-1 or analogs to abolish catabolic changes after surgery
|
|
US6174905B1
(en)
|
1996-09-30 |
2001-01-16 |
Mitsui Chemicals, Inc. |
Cell differentiation inducer
|
|
WO1998018763A1
(en)
|
1996-10-25 |
1998-05-07 |
Tanabe Seiyaku Co., Ltd. |
Tetrahydroisoquinoline derivatives
|
|
TW492957B
(en)
|
1996-11-07 |
2002-07-01 |
Novartis Ag |
N-substituted 2-cyanopyrrolidnes
|
|
US6011155A
(en)
|
1996-11-07 |
2000-01-04 |
Novartis Ag |
N-(substituted glycyl)-2-cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
|
IL130181A0
(en)
|
1996-12-05 |
2000-06-01 |
Amgen Inc |
Substituted pyrimidone and pyridone compounds and methods of use
|
|
GB9702701D0
(en)
|
1997-02-01 |
1997-04-02 |
Univ Newcastle Ventures Ltd |
Quinazolinone compounds
|
|
US20030060434A1
(en)
|
1997-02-18 |
2003-03-27 |
Loretta Nielsen |
Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms
|
|
US6100234A
(en)
|
1997-05-07 |
2000-08-08 |
Tufts University |
Treatment of HIV
|
|
DE69840230D1
(de)
|
1997-05-16 |
2009-01-02 |
Novozymes Inc |
Polypeptide mit prolyldipeptidylaminopeptidase-aktivität und dafür kodierende nukleinsäuren
|
|
EP0897012A1
(en)
|
1997-07-05 |
1999-02-17 |
Societe Des Produits Nestle S.A. |
Cloning of the prolyl-dipeptidyl-peptidase from aspergillus oryzae
|
|
US6235493B1
(en)
|
1997-08-06 |
2001-05-22 |
The Regents Of The University Of California |
Amino acid substituted-cresyl violet, synthetic fluorogenic substrates for the analysis of agents in individual in vivo cells or tissue
|
|
IL125950A0
(en)
|
1997-09-05 |
1999-04-11 |
Pfizer Prod Inc |
Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
|
|
CA2304206A1
(en)
|
1997-09-29 |
1999-04-08 |
Point Therapeutics, Inc. |
Stimulation of hematopoietic cells in vitro
|
|
US6485955B1
(en)
|
1997-10-06 |
2002-11-26 |
The Trustees Of Tufts University |
Quiescent cell dipeptidyl peptidase: a novel cytoplasmic serine protease
|
|
WO1999017799A1
(en)
|
1997-10-06 |
1999-04-15 |
Trustees Of Tufts College Et Al. |
Cytoplasmic dipeptidylpeptidase iv from human t-cells
|
|
BR9814816A
(pt)
|
1997-10-10 |
2004-06-22 |
Cytovia Inc |
Novas moléculas repórter fluorescentes e suas aplicações incluindo análises de caspases
|
|
US6342611B1
(en)
*
|
1997-10-10 |
2002-01-29 |
Cytovia, Inc. |
Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
|
|
JP4095772B2
(ja)
*
|
1997-11-18 |
2008-06-04 |
財団法人微生物化学研究会 |
新規生理活性物質スルフォスチン、その製造法及びその用途
|
|
FR2771004B1
(fr)
*
|
1997-11-19 |
2000-02-18 |
Inst Curie |
Utilisation de derives de benzhydryl sulfinyle pour la fabrication de medicaments ayant un effet eveillant dans des situations de troubles de la vigilance d'origine medicamenteuse
|
|
WO1999028474A2
(en)
|
1997-12-01 |
1999-06-10 |
The Government Of The United States Of America, Represented By The Secretary Of Health And Human Services |
Chemokine variants and methods of use
|
|
ATE319818T1
(de)
*
|
1997-12-16 |
2006-03-15 |
Novozymes As |
Polypeptide mit aminopeptidaseaktivität und für diese kodierende nukleinsäuren
|
|
US6380357B2
(en)
|
1997-12-16 |
2002-04-30 |
Eli Lilly And Company |
Glucagon-like peptide-1 crystals
|
|
AU766219B2
(en)
|
1998-02-02 |
2003-10-09 |
1149336 Ontario Inc. |
Method of regulating glucose metabolism, and reagents related thereto
|
|
AU3034299A
(en)
|
1998-03-09 |
1999-09-27 |
Fondatech Benelux N.V. |
Serine peptidase modulators
|
|
US20020061839A1
(en)
|
1998-03-09 |
2002-05-23 |
Scharpe Simon Lodewijk |
Serine peptidase modulators
|
|
CA2333927A1
(en)
|
1998-04-01 |
1999-10-07 |
Dupont Pharmaceuticals Company |
Pyrimidines and triazines as integrin antagonists
|
|
FR2777283B1
(fr)
|
1998-04-10 |
2000-11-24 |
Adir |
Nouveaux composes peptidiques analogues du glucagon-peptide- 1 (7-37), leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
DE19823831A1
(de)
|
1998-05-28 |
1999-12-02 |
Probiodrug Ges Fuer Arzneim |
Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen
|
|
AU765370B2
(en)
*
|
1998-06-05 |
2003-09-18 |
Point Therapeutics, Inc. |
Cyclic boroproline compounds
|
|
DE19828114A1
(de)
|
1998-06-24 |
2000-01-27 |
Probiodrug Ges Fuer Arzneim |
Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
|
|
DE19828113A1
(de)
|
1998-06-24 |
2000-01-05 |
Probiodrug Ges Fuer Arzneim |
Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
|
|
US6129911A
(en)
|
1998-07-10 |
2000-10-10 |
Rhode Island Hospital, A Lifespan Partner |
Liver stem cell
|
|
DE19834591A1
(de)
|
1998-07-31 |
2000-02-03 |
Probiodrug Ges Fuer Arzneim |
Verfahren zur Steigerung des Blutglukosespiegels in Säugern
|
|
AU5027299A
(en)
|
1998-07-31 |
2000-02-28 |
Novo Nordisk A/S |
Use of glp-1 and analogues for preventing type ii diabetes
|
|
ATE445006T1
(de)
|
1998-08-10 |
2009-10-15 |
Us Gov Health & Human Serv |
Differenzierung von nicht-insulin in insulin- produzierende zellen durch glp-1 und exendin-4 und dessen verwendung
|
|
EP1104293A1
(en)
|
1998-08-21 |
2001-06-06 |
Point Therapeutics, Inc. |
Regulation of substrate activity
|
|
CA2344246A1
(en)
|
1998-09-17 |
2000-03-23 |
Akesis Pharmaceuticals, Inc. |
Combinations of chromium or vanadium with antidiabetics for glucose metabolism disorders
|
|
DE19845153A1
(de)
|
1998-10-01 |
2000-04-06 |
Merck Patent Gmbh |
Imidazo[4,5]-pyridin-4-on-derivate
|
|
US20030176357A1
(en)
|
1998-10-06 |
2003-09-18 |
Pospisilik Andrew J. |
Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels
|
|
CO5150173A1
(es)
|
1998-12-10 |
2002-04-29 |
Novartis Ag |
Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv
|
|
DE19900471A1
(de)
|
1999-01-08 |
2000-07-13 |
Merck Patent Gmbh |
Imidazo[4,5c]-pyridin-4-on-derivate
|
|
IL144461A0
(en)
|
1999-01-22 |
2002-05-23 |
Kirin Brewery |
Quinoline and quinazoline derivatives and pharmaceutical compositions containing them
|
|
DE60045030D1
(de)
|
1999-02-10 |
2010-11-11 |
Curis Inc |
Peptid yy (pyy) zur behandlung von glukose stoffwechselkrankheiten
|
|
AU3960400A
(en)
|
1999-03-05 |
2000-09-28 |
Molteni L. E C. Dei Fratelli Alitti Societa' Di Esercizio S.P.A. |
Use of metformin in the preparation of pharmaceutical compositions capable of inhibiting the enzyme dipeptidyl peptidase iv
|
|
GB9906715D0
(en)
|
1999-03-23 |
1999-05-19 |
Ferring Bv |
Compositions for promoting growth
|
|
GB9906714D0
(en)
|
1999-03-23 |
1999-05-19 |
Ferring Bv |
Compositions for improving fertility
|
|
WO2000057721A2
(en)
|
1999-03-26 |
2000-10-05 |
Akesis Pharmaceuticals, Inc. |
Edible solids for treatment of glucose metabolism disorders
|
|
US6548529B1
(en)
*
|
1999-04-05 |
2003-04-15 |
Bristol-Myers Squibb Company |
Heterocyclic containing biphenyl aP2 inhibitors and method
|
|
JP2002542246A
(ja)
|
1999-04-20 |
2002-12-10 |
ノボ ノルディスク アクティーゼルスカブ |
新規な化合物、それらの製造及び使用
|
|
CA2363712C
(en)
*
|
1999-05-17 |
2011-05-10 |
Conjuchem Inc. |
Long lasting insulinotropic peptides
|
|
DE19926233C1
(de)
|
1999-06-10 |
2000-10-19 |
Probiodrug Ges Fuer Arzneim |
Verfahren zur Herstellung von Thiazolidin
|
|
US6110949A
(en)
|
1999-06-24 |
2000-08-29 |
Novartis Ag |
N-(substituted glycyl)-4-cyanothiazolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
|
US6107317A
(en)
|
1999-06-24 |
2000-08-22 |
Novartis Ag |
N-(substituted glycyl)-thiazolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
|
US6172081B1
(en)
*
|
1999-06-24 |
2001-01-09 |
Novartis Ag |
Tetrahydroisoquinoline 3-carboxamide derivatives
|
|
US6528486B1
(en)
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
|
US6617340B1
(en)
|
1999-07-29 |
2003-09-09 |
Novartis Ag |
N-(substituted glycyl)-pyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
|
DE19940130A1
(de)
*
|
1999-08-24 |
2001-03-01 |
Probiodrug Ges Fuer Arzneim |
Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
|
|
ES2269178T3
(es)
|
1999-09-10 |
2007-04-01 |
The University Of Sydney |
Dipeptidil peptidasas.
|
|
US6559188B1
(en)
|
1999-09-17 |
2003-05-06 |
Novartis Ag |
Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
|
|
US6414002B1
(en)
|
1999-09-22 |
2002-07-02 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
|
|
CA2385918A1
(en)
|
1999-09-28 |
2001-04-05 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Quinazolinones
|
|
US6251391B1
(en)
|
1999-10-01 |
2001-06-26 |
Klaire Laboratories, Inc. |
Compositions containing dipepitidyl peptidase IV and tyrosinase or phenylalaninase for reducing opioid-related symptons
|
|
US6447772B1
(en)
|
1999-10-01 |
2002-09-10 |
Klaire Laboratories, Inc. |
Compositions and methods relating to reduction of symptoms of autism
|
|
EP1229024A1
(en)
|
1999-10-08 |
2002-08-07 |
Meiji Seika Kaisha Ltd. |
m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM
|
|
US6261794B1
(en)
|
1999-10-14 |
2001-07-17 |
Saint Louis University |
Methods for identifying inhibitors of methionine aminopeptidases
|
|
US7230000B1
(en)
|
1999-10-27 |
2007-06-12 |
Cytokinetics, Incorporated |
Methods and compositions utilizing quinazolinones
|
|
US20040152745A1
(en)
|
1999-11-12 |
2004-08-05 |
Guilford Pharmaceuticals, Inc. |
Dipeptidyl peptidase IV inhibitors and methods of making and using dipeptidyl peptidase IV inhibitors
|
|
EP1228061A4
(en)
|
1999-11-12 |
2004-12-15 |
Guilford Pharm Inc |
DIPEPTIDYL PEPTIDASE IV INHIBITORS; METHODS OF MANUFACTURE AND USE OF SAID INHIBITORS
|
|
GB9928330D0
(en)
|
1999-11-30 |
2000-01-26 |
Ferring Bv |
Novel antidiabetic agents
|
|
WO2001041779A2
(en)
*
|
1999-12-08 |
2001-06-14 |
1149336 Ontario Inc. |
Combined use of glp-2 receptor agonist and chemotherapeutic agent in treatment
|
|
US6380398B2
(en)
|
2000-01-04 |
2002-04-30 |
Novo Nordisk A/S |
Therapeutically active and selective heterocyclic compounds that are inhibitors of the enzyme DPP-IV
|
|
PT1741446E
(pt)
|
2000-01-21 |
2008-05-09 |
Novartis Pharma Ag |
Combinações incluindo inibidores da dipeptidilpeptidase-iv e agentes anti-diabéticos
|
|
AU2001228309A1
(en)
|
2000-01-24 |
2001-08-07 |
Novo-Nordisk A/S |
N-substituted 2-cyanopyroles and -pyrrolines which are inhibitors of the enzyme dpp-iv
|
|
PT1255738E
(pt)
|
2000-01-25 |
2012-06-19 |
Neurocrine Biosciences Inc |
Antagonistas do receptor da hormona de libertação da gonadotrofina e métodos relacionados com os mesmos
|
|
TR200401142T4
(tr)
*
|
2000-01-27 |
2004-07-21 |
Eli Lilly And Company |
Glükagon-benzeri peptid bileşiklerinin çözündürülmesi için işlem.
|
|
US6569901B2
(en)
|
2000-01-28 |
2003-05-27 |
Novo Nordisk A/S |
Alkynyl-substituted propionic acid derivatives, their preparation and use
|
|
US7217722B2
(en)
|
2000-02-01 |
2007-05-15 |
Kirin Beer Kabushiki Kaisha |
Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
|
|
WO2001062266A2
(en)
|
2000-02-25 |
2001-08-30 |
Novo Nordisk A/S |
Use of dpp-iv inhibitors for the treatment of diabetes
|
|
US6395767B2
(en)
*
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
|
US6448045B1
(en)
|
2000-03-10 |
2002-09-10 |
The Regents Of The University Of California |
Inducing insulin gene expression in pancreas cells expressing recombinant PDX-1
|
|
US6608038B2
(en)
|
2000-03-15 |
2003-08-19 |
Novartis Ag |
Methods and compositions for treatment of diabetes and related conditions via gene therapy
|
|
EP1136482A1
(en)
|
2000-03-23 |
2001-09-26 |
Sanofi-Synthelabo |
2-Amino-3-(alkyl)-pyrimidone derivatives as GSK3beta inhibitors
|
|
AU2001248701A1
(en)
|
2000-03-24 |
2001-10-03 |
Methylgene, Inc. |
Inhibitors of histone deacetylase
|
|
US6555519B2
(en)
*
|
2000-03-30 |
2003-04-29 |
Bristol-Myers Squibb Company |
O-glucosylated benzamide SGLT2 inhibitors and method
|
|
HU229042B1
(en)
|
2000-03-31 |
2013-07-29 |
Prosidion Ltd |
Method for the improvement of islet signaling in diabetes mellitus and for its prevention
|
|
US6573096B1
(en)
|
2000-04-01 |
2003-06-03 |
The Research Foundation At State University Of New York |
Compositions and methods for inhibition of cancer invasion and angiogenesis
|
|
US6545170B2
(en)
|
2000-04-13 |
2003-04-08 |
Pharmacia Corporation |
2-amino-5, 6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors
|
|
EP1288216A1
(en)
|
2000-04-18 |
2003-03-05 |
Sumitomo Pharmaceuticals Company, Limited |
Tricyclic quinazolinediones
|
|
ES2788383T3
(es)
|
2000-04-25 |
2020-10-21 |
Icos Corp |
Inhibidores de delta fosfatidilo-inositol 3-quinasa humana
|
|
GB0010188D0
(en)
|
2000-04-26 |
2000-06-14 |
Ferring Bv |
Inhibitors of dipeptidyl peptidase IV
|
|
GB0010183D0
(en)
|
2000-04-26 |
2000-06-14 |
Ferring Bv |
Inhibitors of dipeptidyl peptidase IV
|
|
DE10025464A1
(de)
|
2000-05-23 |
2001-12-06 |
Inst Medizintechnologie Magdeb |
Kombinierte Verwendung von Enzyminhibitoren zur Therapie von Autoimmunerkrankungen, bei Transplantationen und Tumorerkrankungen sowie Kombinationen von Enzyminhibitoren umfassende pharmazeutische Zubereitungen
|
|
US6783757B2
(en)
|
2000-06-01 |
2004-08-31 |
Kirkman Group, Inc. |
Composition and method for increasing exorphin catabolism to treat autism
|
|
AU2001263786A1
(en)
|
2000-06-09 |
2001-12-17 |
Prozymex A/S |
Purified proenzyme of dipeptidyl peptidase i (pro-dppi)
|
|
US6432969B1
(en)
|
2000-06-13 |
2002-08-13 |
Novartis Ag |
N-(substituted glycyl)-2 cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
|
TW583185B
(en)
|
2000-06-13 |
2004-04-11 |
Novartis Ag |
N-(substituted glycyl)-2-cyanopyrrolidines and pharmaceutical composition for inhibiting dipeptidyl peptidase-IV (DPP-IV) or for the prevention or treatment of diseases or conditions associated with elevated levels of DPP-IV comprising the same
|
|
US6620821B2
(en)
|
2000-06-15 |
2003-09-16 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
|
US6627636B2
(en)
|
2000-06-15 |
2003-09-30 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
|
GB0014969D0
(en)
|
2000-06-19 |
2000-08-09 |
Smithkline Beecham Plc |
Novel method of treatment
|
|
US7078397B2
(en)
|
2000-06-19 |
2006-07-18 |
Smithkline Beecham Corporation |
Combinations of dipeptidyl peptidase IV inhibitors and other antidiabetic agents for the treatment of diabetes mellitus
|
|
WO2002002560A2
(en)
|
2000-07-04 |
2002-01-10 |
Novo Nordisk A/S |
Purine-2,6-diones which are inhibitors of the enzyme dipeptidyl peptidase iv (dpp-iv)
|
|
WO2002004610A2
(en)
|
2000-07-10 |
2002-01-17 |
Bayer Aktiengesellschaft |
Regulation of human dipeptidyl-peptidase iv-like enzyme
|
|
TW535080B
(en)
|
2000-07-24 |
2003-06-01 |
Ten Square Co Ltd |
Method and apparatus for optimal fitting activities into customer idle time
|
|
JP2002042960A
(ja)
*
|
2000-07-25 |
2002-02-08 |
Yazaki Corp |
コネクタ支持機構
|
|
US6518269B1
(en)
|
2000-07-28 |
2003-02-11 |
University Of Arizona Foundation |
Cancer treatment
|
|
WO2002010139A1
(en)
|
2000-08-01 |
2002-02-07 |
Pharmacia Corporation |
Hexahydro-7-1h-azepin-2-yl-haxanoic acid derivatives as inhibitors of inducible nitric oxide synthase
|
|
CA2417942C
(en)
|
2000-08-04 |
2010-06-29 |
Warner-Lambert Company |
2-(4-pyridyl)amino-6-dialkoxyphenyl-pyrido[2,3-d]pyrimidin-7-ones
|
|
US7074794B2
(en)
|
2000-08-10 |
2006-07-11 |
Mitsubishi Pharma Corporation |
Proline derivatives and the use thereof as drugs
|
|
US20020165237A1
(en)
|
2000-08-11 |
2002-11-07 |
Fryburg David Albert |
Treatment of the insulin resistance syndrome
|
|
US20020037829A1
(en)
|
2000-08-23 |
2002-03-28 |
Aronson Peter S. |
Use of DPPIV inhibitors as diuretic and anti-hypertensive agents
|
|
US6900226B2
(en)
|
2000-09-06 |
2005-05-31 |
Hoffman-La Roche Inc. |
Neuropeptide Y antagonists
|
|
DE60131423T2
(de)
|
2000-09-08 |
2009-03-19 |
Prozymex A/S |
Ratten-spezifische cathepsin, dipeptidyl peptidase i (dppi): kristallstruktur, hemmstoffe und deren anwendungen
|
|
AU2001292874B2
(en)
|
2000-09-27 |
2006-06-15 |
Merck & Co., Inc. |
Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders
|
|
US20020064736A1
(en)
|
2000-09-27 |
2002-05-30 |
Fuji Photo Film Co., Ltd. |
Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye
|
|
GB0023983D0
(en)
|
2000-09-29 |
2000-11-15 |
Prolifix Ltd |
Therapeutic compounds
|
|
SE0003599D0
(sv)
|
2000-10-05 |
2000-10-05 |
Thomas Johansson |
Anordning för fuktabsorption
|
|
US7138397B2
(en)
|
2000-10-06 |
2006-11-21 |
Tanabe Seiyaku Co., Ltd. |
Nitrogenous 5-membered ring compounds
|
|
CZ20031301A3
(cs)
|
2000-10-12 |
2003-10-15 |
Ferring Bv |
Izolovaná nukleová kyselina, polypeptid, expresní vektor a protilátka
|
|
KR20030096227A
(ko)
|
2000-10-27 |
2003-12-24 |
프로비오드룩 아게 |
신경 및 신경정신 질환의 치료방법
|
|
AUPR107800A0
(en)
|
2000-10-27 |
2000-11-23 |
University Of Sydney, The |
Peptide and nucleic acid molecule ii
|
|
MXPA03003870A
(es)
|
2000-10-30 |
2004-08-12 |
Johnson & Johnson |
Terapia de combinacion que comprende agentes antidiabeticos y anticonvulsionantes.
|
|
JP4350946B2
(ja)
|
2000-10-31 |
2009-10-28 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病及び脂質異常症の治療のためのベンゾピランカルボン酸誘導体
|
|
WO2002059343A2
(en)
|
2000-10-31 |
2002-08-01 |
Vanderbilt University |
Biological markers and diagnostic tests for angiotensin converting enzyme inhibitor- and vasopeptidase inhibitor-associated angioedema
|
|
WO2002038742A2
(en)
|
2000-11-08 |
2002-05-16 |
The University Of Georgia Research Foundation, Inc. |
Dipeptidylpeptidases and methods of use
|
|
US20020155565A1
(en)
|
2000-11-10 |
2002-10-24 |
Pilar Garin-Chesa |
FAP-activated anti-tumor compounds
|
|
US20030055052A1
(en)
|
2000-11-10 |
2003-03-20 |
Stefan Peters |
FAP-activated anti-tumor compounds
|
|
TWI243162B
(en)
|
2000-11-10 |
2005-11-11 |
Taisho Pharmaceutical Co Ltd |
Cyanopyrrolidine derivatives
|
|
US20030203946A1
(en)
|
2000-11-17 |
2003-10-30 |
Carsten Behrens |
Glucagon antagonists/inverse agonists
|
|
US6670380B2
(en)
|
2000-11-20 |
2003-12-30 |
Bristol-Myers Squibb Co. |
Pyridone inhibitors of fatty acid binding protein and method
|
|
MXPA03005152A
(es)
|
2000-12-11 |
2004-10-14 |
Tularik Inc |
Antogonista de cxcr3.
|
|
WO2002051836A1
(en)
|
2000-12-27 |
2002-07-04 |
Kyowa Hakko Kogyo Co., Ltd. |
Dipeptidyl peptidase iv inhibitor
|
|
DE10100053A1
(de)
|
2001-01-02 |
2002-08-22 |
Keyneurotek Ag I G |
Verwendung von Enzyminhibitoren der Dipeptidylpeptidase IV sowie der Aminopeptidase N und pharmazeutischen Zubereitungen daraus zur Prävention und/oder Therapie Ischämie-bedingter akuter und chronischer neurodegenerativer Prozesse und Erkrankungen
|
|
JP2004520330A
(ja)
|
2001-01-02 |
2004-07-08 |
インスティテュート ヒューア メディツィンテクノロギー マグデブルク ゲーエムベーハー イーエムテーエム |
動脈硬化症の治療と予防的治療、ゲル−クームズ分類ｉ型のアレルギー反応の治療と予防、ならびに、毛包性および表皮性の過角化症とケラチノサイトの促進された増殖を伴う皮膚病の治療と予防のための、酵素阻害因子およびその薬剤化合物の併用
|
|
WO2002059301A1
(en)
|
2001-01-27 |
2002-08-01 |
K.U. Leuven Research And Development |
Chemokines
|
|
CN1500080A
(zh)
|
2001-02-02 |
2004-05-26 |
����ҩƷ��ҵ��ʽ���� |
稠合杂环化合物
|
|
TWI255817B
(en)
|
2001-02-14 |
2006-06-01 |
Kissei Pharmaceutical |
Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
|
|
WO2002066627A1
(en)
|
2001-02-16 |
2002-08-29 |
Bayer Aktiengesellschaft |
Regulation of human dipeptidyl peptidase 8
|
|
KR100926247B1
(ko)
|
2001-02-24 |
2009-11-12 |
베링거 잉겔하임 파르마 게엠베하 운트 코 카게 |
크산틴 유도체를 포함하는 약제학적 조성물 및 이의제조방법
|
|
US6337069B1
(en)
|
2001-02-28 |
2002-01-08 |
B.M.R.A. Corporation B.V. |
Method of treating rhinitis or sinusitis by intranasally administering a peptidase
|
|
JP4178816B2
(ja)
|
2001-03-15 |
2008-11-12 |
田辺三菱製薬株式会社 |
医薬組成物
|
|
SK287334B6
(sk)
|
2001-03-19 |
2010-07-07 |
Novartis Ag |
Kombinácia protihnačkového činidla a epotilónu alebo jeho derivátu, farmaceutická kompozícia a obchodné balenie, ktoré ju obsahujú, a jej použitie
|
|
ATE395912T1
(de)
|
2001-03-27 |
2008-06-15 |
Merck & Co Inc |
Dipeptidylpeptidase-hemmer für die behandlung oder prävention von diabetes
|
|
FR2822826B1
(fr)
*
|
2001-03-28 |
2003-05-09 |
Servier Lab |
Nouveaux derives sulfonyles d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
DE10115921A1
(de)
|
2001-03-30 |
2002-10-02 |
Boehringer Ingelheim Pharma |
Verfahren zur Herstellung von 4,6-Diaminopyrimido[5,4-d]pyrimidinen
|
|
US6890905B2
(en)
|
2001-04-02 |
2005-05-10 |
Prosidion Limited |
Methods for improving islet signaling in diabetes mellitus and for its prevention
|
|
GB0109146D0
(en)
|
2001-04-11 |
2001-05-30 |
Ferring Bv |
Treatment of type 2 diabetes
|
|
US6573287B2
(en)
|
2001-04-12 |
2003-06-03 |
Bristo-Myers Squibb Company |
2,1-oxazoline and 1,2-pyrazoline-based inhibitors of dipeptidyl peptidase IV and method
|
|
PE20021080A1
(es)
|
2001-04-12 |
2003-02-12 |
Boehringer Ingelheim Int |
Un anticuerpo especifico fapo bibh1 en el tratamiento del cancer
|
|
EP1392361A4
(en)
|
2001-05-11 |
2009-08-05 |
Univ Texas |
ANTI-CD26 MONOCLONAL ANTIBODIES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH CD26 EXPRESSIVE CELLS
|
|
FR2824825B1
(fr)
*
|
2001-05-15 |
2005-05-06 |
Servier Lab |
Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
US20030060494A1
(en)
|
2001-05-18 |
2003-03-27 |
Nobuyuki Yasuda |
Pharmaceutical use of N-carbamoylazole derivatives
|
|
IL143366A0
(en)
|
2001-05-24 |
2002-04-21 |
Harasit Medical Res Services & |
Treatment of renal fibrosis
|
|
US7105556B2
(en)
|
2001-05-30 |
2006-09-12 |
Bristol-Myers Squibb Company |
Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method
|
|
US6794379B2
(en)
|
2001-06-06 |
2004-09-21 |
Tularik Inc. |
CXCR3 antagonists
|
|
ES2257555T3
(es)
|
2001-06-20 |
2006-08-01 |
MERCK & CO., INC. |
Inhibidores de dipeptidilpeptidasa para el tratamiento de la diabetes.
|
|
EP1406872B1
(en)
|
2001-06-20 |
2007-12-19 |
Merck & Co., Inc. |
Dipeptidyl peptidase inhibitors for the treatment of diabetes
|
|
GB0115517D0
(en)
|
2001-06-25 |
2001-08-15 |
Ferring Bv |
Novel antidiabetic agents
|
|
CA2418543A1
(en)
|
2001-06-27 |
2003-01-09 |
Probiodrug Ag |
New dipeptidyl peptidase iv inhibitors and their uses as anti-cancer agents
|
|
DE60221983T2
(de)
|
2001-06-27 |
2008-05-15 |
Smithkline Beecham Corp. |
Fluorpyrrolidine als dipeptidyl-peptidase inhibitoren
|
|
ES2296979T3
(es)
|
2001-06-27 |
2008-05-01 |
Smithkline Beecham Corporation |
Fluoropirrolidinas como inhibidores de dipeptidil peptidasa.
|
|
US20030130199A1
(en)
|
2001-06-27 |
2003-07-10 |
Von Hoersten Stephan |
Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
|
|
US7368421B2
(en)
|
2001-06-27 |
2008-05-06 |
Probiodrug Ag |
Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
|
|
DE10154689A1
(de)
|
2001-11-09 |
2003-05-22 |
Probiodrug Ag |
Substituierte Aminoketonverbindungen
|
|
DE10150203A1
(de)
|
2001-10-12 |
2003-04-17 |
Probiodrug Ag |
Peptidylketone als Inhibitoren der DPIV
|
|
US20030135023A1
(en)
|
2001-06-27 |
2003-07-17 |
Hans-Ulrich Demuth |
Peptide structures useful for competitive modulation of dipeptidyl peptidase IV catalysis
|
|
JP4300108B2
(ja)
|
2001-06-27 |
2009-07-22 |
スミスクライン ビーチャム コーポレーション |
ジペプチジルペプチダーゼ阻害剤としてのピロリジン類
|
|
US6869947B2
(en)
|
2001-07-03 |
2005-03-22 |
Novo Nordisk A/S |
Heterocyclic compounds that are inhibitors of the enzyme DPP-IV
|
|
WO2003004496A1
(en)
|
2001-07-03 |
2003-01-16 |
Novo Nordisk A/S |
Dpp-iv-inhibiting purine derivatives for the treatment of diabetes
|
|
UA74912C2
(en)
|
2001-07-06 |
2006-02-15 |
Merck & Co Inc |
Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
|
|
WO2003007888A2
(en)
|
2001-07-20 |
2003-01-30 |
Adipogenix, Inc. |
Fat accumulation-modulating compounds
|
|
WO2003010197A2
(en)
|
2001-07-25 |
2003-02-06 |
Genset S.A. |
Gmg-1 polynucleotides and polypeptides and uses thereof
|
|
IL159872A0
(en)
|
2001-07-26 |
2004-06-20 |
Genset Sa |
Gmg-2 polypeptides and their use
|
|
BR0211414A
(pt)
|
2001-07-30 |
2004-08-17 |
Novo Nordisk As |
Composto, uso do mesmo, composição farmacêutica, e, métodos para o tratamento e/ou prevenção de condições mediadas pelos receptores nucleares e de diabetes tipo i, diabetes tipo ii, tolerância à glicose, resistência à insulina ou obesidade prejudicadas
|
|
JP2004536152A
(ja)
|
2001-07-30 |
2004-12-02 |
ノボ ノルディスク アクティーゼルスカブ |
新規ビニルｎ−（２−ベンゾイルフェニル）−ｌ−チロシン誘導体及び抗糖尿病剤等へのそれらの使用
|
|
EP1411968B1
(en)
|
2001-07-31 |
2008-09-17 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Glp-1 exendin-4 peptide analogs and uses thereof
|
|
US20040002468A1
(en)
|
2001-08-08 |
2004-01-01 |
Genzyme Corporation |
Methods of treating diabetes and other blood sugar disorders
|
|
AU2002328946A1
(en)
|
2001-08-13 |
2003-03-03 |
Probiodrug Ag |
Irreversible cysteine protease inhibitors of legumain
|
|
EP1285922A1
(en)
|
2001-08-13 |
2003-02-26 |
Warner-Lambert Company |
1-Alkyl or 1-cycloalkyltriazolo[4,3-a]quinazolin-5-ones as phosphodiesterase inhibitors
|
|
JP2003128551A
(ja)
|
2001-08-15 |
2003-05-08 |
Sankyo Co Ltd |
新規抗糖尿病医薬組成物
|
|
DE10143840A1
(de)
|
2001-09-06 |
2003-03-27 |
Probiodrug Ag |
Neue Inhibitoren der Dipeptidylpeptidase I
|
|
US6844316B2
(en)
|
2001-09-06 |
2005-01-18 |
Probiodrug Ag |
Inhibitors of dipeptidyl peptidase I
|
|
US20030186963A1
(en)
|
2001-09-14 |
2003-10-02 |
Dorwald Florencio Zaragoza |
Substituted piperidines
|
|
WO2003024942A1
(en)
|
2001-09-14 |
2003-03-27 |
Mitsubishi Pharma Corporation |
Thiazolidine derivative and medicinal use thereof
|
|
US6673829B2
(en)
|
2001-09-14 |
2004-01-06 |
Novo Nordisk A/S |
Aminoazetidine,-pyrrolidine and -piperidine derivatives
|
|
EP1463727A2
(en)
|
2001-09-19 |
2004-10-06 |
Novo Nordisk A/S |
Heterocyclic compounds that are inhibitors of the enzyme dpp-iv
|
|
CA2461202C
(en)
|
2001-09-21 |
2011-07-12 |
Donald Pinto |
Lactam-containing compounds and derivatives thereof as factor xa inhibitors
|
|
AU2002337499B2
(en)
|
2001-09-21 |
2007-08-23 |
Mitsubishi Pharma Corporation |
3-substituted-4-pyrimidone derivatives
|
|
KR100754596B1
(ko)
|
2001-09-21 |
2007-09-05 |
미쯔비시 웰 파마 가부시키가이샤 |
3-치환-4-피리미돈 유도체
|
|
US7019010B2
(en)
|
2001-09-27 |
2006-03-28 |
Novertis Ag |
Combinations
|
|
CA2462112A1
(en)
*
|
2001-10-01 |
2003-04-10 |
Bristol-Myers Squibb Company |
Spiro-hydantoin compounds useful as anti-inflammatory agents
|
|
WO2003030946A1
(en)
|
2001-10-09 |
2003-04-17 |
Novartis Ag |
Regulation of insulin production
|
|
US7064135B2
(en)
|
2001-10-12 |
2006-06-20 |
Novo Nordisk Inc. |
Substituted piperidines
|
|
CA2463908A1
(en)
|
2001-10-18 |
2003-04-24 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
TWI301834B
(en)
|
2001-10-22 |
2008-10-11 |
Eisai R&D Man Co Ltd |
Pyrimidone compound and pharmaceutical composition including the same
|
|
GB0125446D0
(en)
|
2001-10-23 |
2001-12-12 |
Ferring Bv |
Novel anti-diabetic agents
|
|
GB0125445D0
(en)
|
2001-10-23 |
2001-12-12 |
Ferring Bv |
Protease Inhibitors
|
|
US6861440B2
(en)
|
2001-10-26 |
2005-03-01 |
Hoffmann-La Roche Inc. |
DPP IV inhibitors
|
|
CA2464995A1
(en)
|
2001-10-31 |
2003-05-08 |
Novartis Ag |
Methods to treat diabetes and related conditions based on polymorphisms in the tcf1 gene
|
|
EP1442028A4
(en)
|
2001-11-06 |
2009-11-04 |
Bristol Myers Squibb Co |
SUBSTITUTED ACID DERIVATIVES, WHICH APPRECIATE AS ANTIDIBILICS AND AGENTS AGAINST OBESITAS, AND METHODS
|
|
US20030125304A1
(en)
|
2001-11-09 |
2003-07-03 |
Hans-Ulrich Demuth |
Substituted amino ketone compounds
|
|
US20030089935A1
(en)
|
2001-11-13 |
2003-05-15 |
Macronix International Co., Ltd. |
Non-volatile semiconductor memory device with multi-layer gate insulating structure
|
|
IL161717A0
(en)
|
2001-11-26 |
2004-09-27 |
Schering Corp |
Piperidine-based mch antagonists for treatment of obesity and cns disorders
|
|
EP1469873A4
(en)
|
2001-11-26 |
2007-10-03 |
Tufts College |
PEPTIDOMIMETIC INHIBITORS FROM BEHIND PROLIN SPLENDING ENZYMES
|
|
WO2003045228A2
(en)
|
2001-11-26 |
2003-06-05 |
Trustees Of Tufts College |
Methods for treating autoimmune disorders, and reagents related thereto
|
|
AU2002350217A1
(en)
|
2001-12-04 |
2003-06-17 |
Bristol-Myers Squibb Company |
Glycinamides as factor xa inhibitors
|
|
KR20040068240A
(ko)
|
2001-12-14 |
2004-07-30 |
노보 노르디스크 에이/에스 |
호르몬 민감성 리파아제의 활성을 감소시키기 위한 화합물및 그들의 사용
|
|
GB0129988D0
(en)
|
2001-12-14 |
2002-02-06 |
Ferring Bv |
Imidazolidineacetic acid derivatives
|
|
SE0104340D0
(sv)
|
2001-12-20 |
2001-12-20 |
Astrazeneca Ab |
New compounds
|
|
TW200301698A
(en)
|
2001-12-21 |
2003-07-16 |
Bristol Myers Squibb Co |
Acridone inhibitors of IMPDH enzyme
|
|
WO2003055482A1
(en)
|
2001-12-21 |
2003-07-10 |
Novo Nordisk A/S |
Amide derivatives as gk activators
|
|
AU2002360732A1
(en)
|
2001-12-26 |
2003-07-24 |
Guilford Pharmaceuticals |
Change inhibitors of dipeptidyl peptidase iv
|
|
US6727261B2
(en)
|
2001-12-27 |
2004-04-27 |
Hoffman-La Roche Inc. |
Pyrido[2,1-A]Isoquinoline derivatives
|
|
JP2005516968A
(ja)
|
2001-12-29 |
2005-06-09 |
ノボ ノルディスク アクティーゼルスカブ |
Ｇｌｐ−１化合物と糖尿病後期合併症モジュレーターの組み合わせ使用
|
|
JP2005513165A
(ja)
|
2002-01-11 |
2005-05-12 |
ノボ ノルディスク アクティーゼルスカブ |
糖尿病、高血圧、慢性心不全および体液貯留状態の治療のための方法および組成物
|
|
AU2003218969A1
(en)
|
2002-02-01 |
2003-09-02 |
Probiodrug Ag |
Modulation of t lymphocytes using dp iv inhibitors
|
|
US7101898B2
(en)
|
2002-02-01 |
2006-09-05 |
Novo Nordisk A/S |
Amides of aminoalkyl-substituted azetidines, pyrrolidines, piperidines and azepanes
|
|
WO2003065983A2
(en)
|
2002-02-01 |
2003-08-14 |
Merck & Co., Inc. |
11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia
|
|
KR100608414B1
(ko)
*
|
2002-02-13 |
2006-08-02 |
에프. 호프만-라 로슈 아게 |
신규한 피리딘- 및 피리미딘-유도체
|
|
ES2252656T3
(es)
|
2002-02-13 |
2006-05-16 |
F. Hoffmann-La Roche Ag |
Nuevos derivados de piridina y quinolina.
|
|
NZ534582A
(en)
|
2002-02-27 |
2006-03-31 |
Pfizer Prod Inc |
ACC inhibitors
|
|
JP2005527504A
(ja)
|
2002-02-28 |
2005-09-15 |
プロシディオン・リミテッド |
グルタミニルを基礎するｄｐｉｖ阻害剤
|
|
HUP0200849A2
(hu)
|
2002-03-06 |
2004-08-30 |
Sanofi-Synthelabo |
N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
|
|
ES2361403T3
(es)
|
2002-03-07 |
2011-06-16 |
X-Ceptor Therapeutics, Inc. |
Moduladores de quinazolinona de receptores nucleares.
|
|
CN1274668C
(zh)
|
2002-03-11 |
2006-09-13 |
诺瓦提斯公司 |
那格列奈的盐
|
|
DK1483247T3
(da)
|
2002-03-13 |
2009-08-17 |
Euro Celtique Sa |
Arylsubstituerede pyrimidiner og anvendelsen deraf
|
|
DE10211555A1
(de)
|
2002-03-15 |
2003-10-02 |
Imtm Inst Fuer Medizintechnolo |
Verwendung der Inhibitoren von Enzymen mit Aktivitäten der Aminopeptidase N und/oder der Dipeptidylpeptidase IV und pharmazeutischen Zubereitungen daraus zur Therapie und Prävention dermatologischer Erkrankungen mit sebozytärer Hyperproliferation und veränderten Differenzierungszuständen
|
|
TW200810743A
(en)
|
2002-03-22 |
2008-03-01 |
Novartis Ag |
Combination of organic compounds
|
|
ATE373660T1
(de)
|
2002-03-25 |
2007-10-15 |
Merck & Co Inc |
Heterocyclische beta-aminoverbindungen als inhibitoren der dipeptidylpeptidase zur behandlung bzw. prävention von diabetes
|
|
WO2003080633A1
(fr)
|
2002-03-25 |
2003-10-02 |
Nippon Kayaku Kabushiki Kaisha |
Nouveau derive d'$g(a)-amino-n-(diaminophosphinyl)lactame
|
|
US20030232761A1
(en)
|
2002-03-28 |
2003-12-18 |
Hinke Simon A. |
Novel analogues of glucose-dependent insulinotropic polypeptide
|
|
PE20040079A1
(es)
|
2002-04-03 |
2004-04-19 |
Novartis Ag |
Derivados de indolilmaleimida
|
|
BR0308816A
(pt)
|
2002-04-08 |
2005-03-22 |
Torrent Pharmaceuticals Ltd |
Tiazolidina-4-carbonitrilas e análogos e seus usos como inibidores da dipeptil-peptidas
|
|
US20040106802A1
(en)
|
2002-04-08 |
2004-06-03 |
Torrent Pharmaceuticals Ltd. |
Novel compounds and therapeutic uses thereof
|
|
AU2003228793B2
(en)
|
2002-04-30 |
2008-01-03 |
Trustees Of Tufts College |
Smart Pro-Drugs of Serine Protease Inhibitors
|
|
TW200307667A
(en)
|
2002-05-06 |
2003-12-16 |
Bristol Myers Squibb Co |
Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors
|
|
US7057046B2
(en)
*
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
|
TW200407143A
(en)
|
2002-05-21 |
2004-05-16 |
Bristol Myers Squibb Co |
Pyrrolotriazinone compounds and their use to treat diseases
|
|
WO2003099818A1
(en)
|
2002-05-23 |
2003-12-04 |
Chiron Corporation |
Substituted quinazolinone compounds
|
|
JP4141864B2
(ja)
*
|
2002-05-23 |
2008-08-27 |
株式会社オーエス |
自立式手動昇降スクリーン
|
|
GB0212412D0
(en)
|
2002-05-29 |
2002-07-10 |
Novartis Ag |
Combination of organic compounds
|
|
JP2005533771A
(ja)
|
2002-06-04 |
2005-11-10 |
ファイザー・プロダクツ・インク |
ジペプチジルペプチダーゼｉｖ阻害剤としてのフッ素化環式アミド
|
|
WO2003101449A2
(en)
*
|
2002-06-04 |
2003-12-11 |
Pfizer Products Inc. |
Process for the preparation of 3,3,4,4-tetrafluoropyrrolidine and derivatives thereof
|
|
US6710040B1
(en)
*
|
2002-06-04 |
2004-03-23 |
Pfizer Inc. |
Fluorinated cyclic amides as dipeptidyl peptidase IV inhibitors
|
|
MXPA04012226A
(es)
|
2002-06-06 |
2005-04-08 |
Eisai Co Ltd |
Nuevos derivados de imidazola.
|
|
AR040241A1
(es)
|
2002-06-10 |
2005-03-23 |
Merck & Co Inc |
Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia
|
|
HUP0202001A2
(hu)
|
2002-06-14 |
2005-08-29 |
Sanofi-Aventis |
DDP-IV gátló hatású azabiciklooktán- és nonánszármazékok
|
|
WO2003106628A2
(en)
|
2002-06-17 |
2003-12-24 |
Bristol-Myers Squibb Company |
Benzodiazepine inhibitors of mitochondial f1f0 atp hydrolase and methods of inhibiting f1f0 atp hydrolase
|
|
PL374963A1
(en)
|
2002-06-17 |
2005-11-14 |
Smithkline Beecham Corporation |
Chemical process
|
|
US20040006004A1
(en)
|
2002-06-27 |
2004-01-08 |
Markku Koulu |
Method for prevention and treatment of diseases or disorders related to excessive formation of vascular tissue or blood vessels
|
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
|
US20040054171A1
(en)
|
2002-07-04 |
2004-03-18 |
Jensen Anette Frost |
Polymorphic forms of a 4H-thieno[3,2-E]-1,2,4-thiadiazine 1,1-dioxide derivative
|
|
US20050084490A1
(en)
|
2002-07-09 |
2005-04-21 |
Point Therapeutics, Inc. |
Boroproline compound combination therapy
|
|
BR0312503A
(pt)
|
2002-07-09 |
2007-06-26 |
Bristol Myers Squibb Co |
derivados heterocìclicos substituìdos úteis como agentes antidiabéticos e antiobesidade, composição farmacêutica, uso e combinação dos mesmos
|
|
AU2003259131A1
(en)
|
2002-07-09 |
2004-01-23 |
Bristol-Myers Squibb Company |
Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method
|
|
JP2004099600A
(ja)
|
2002-07-19 |
2004-04-02 |
Sankyo Co Ltd |
二環性アミノ基置換化合物を含有する医薬組成物
|
|
AU2003254852A1
(en)
|
2002-08-08 |
2004-02-25 |
Takeda Pharmaceutical Company Limited |
Fused heterocyclic compounds as peptidase inhibitors
|
|
EP1528931B1
(en)
|
2002-08-09 |
2008-05-07 |
Prosidion Ltd. |
Dipeptidyl peptidase iv inhibitors for decreasing the rate of chronic weight gain
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
EP1532149B9
(de)
|
2002-08-21 |
2011-04-20 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
8-[3-amino-piperidin-1-yl] -xanthine, deren herstellung und deren verwendung als arzneimittel
|
|
DE10238477A1
(de)
|
2002-08-22 |
2004-03-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Purinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7495005B2
(en)
|
2002-08-22 |
2009-02-24 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, their preparation and their use in pharmaceutical compositions
|
|
DE10238470A1
(de)
|
2002-08-22 |
2004-03-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
ZA200501418B
(en)
|
2002-08-29 |
2006-10-25 |
Taisho Pharmaceutical Co Ltd |
Benzenesulfonate salts of 4-fluoro-2-cyanopyrrolidine derivatives
|
|
US6998502B1
(en)
|
2002-09-05 |
2006-02-14 |
Sabinsa Corporation |
Convenient process of manufacture for difluoromethylornithine and related compounds
|
|
EP1398032A1
(en)
|
2002-09-10 |
2004-03-17 |
PheneX Pharmaceuticals AG |
4-Oxo-quinazolines as LXR nuclear receptor binding compounds
|
|
JP2004123738A
(ja)
|
2002-09-11 |
2004-04-22 |
Takeda Chem Ind Ltd |
徐放性製剤
|
|
WO2004024184A1
(ja)
|
2002-09-11 |
2004-03-25 |
Takeda Pharmaceutical Company Limited |
徐放性製剤
|
|
US20040058876A1
(en)
*
|
2002-09-18 |
2004-03-25 |
Torsten Hoffmann |
Secondary binding site of dipeptidyl peptidase IV (DP IV)
|
|
WO2004031374A2
(en)
|
2002-09-18 |
2004-04-15 |
Prosidion Ltd. |
Secondary binding site of dipeptidyl peptidase iv (dp iv)
|
|
ATE368647T1
(de)
|
2002-09-19 |
2007-08-15 |
Abbott Lab |
Pharmazeutische zusammensetzung und ihre verwendung als inhibitoren von der dipeptidyl peptidase iv (dpp-iv)
|
|
US7262207B2
(en)
|
2002-09-19 |
2007-08-28 |
Abbott Laboratories |
Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
|
|
AU2003266559B2
(en)
|
2002-09-26 |
2008-01-24 |
Eisai R&D Management Co., Ltd. |
Combination drug
|
|
US6869966B2
(en)
|
2002-09-30 |
2005-03-22 |
Banyu Pharmaceutical Co., Ltd. |
N-substituted-2-oxodihydropyridine derivatives
|
|
ATE370141T1
(de)
|
2002-10-07 |
2007-09-15 |
Merck & Co Inc |
Antidiabetische heterocyclische beta- aminoverbindungen als inhibitoren von dipeptidylpeptidase
|
|
AU2003269850A1
(en)
|
2002-10-08 |
2004-05-04 |
Novo Nordisk A/S |
Hemisuccinate salts of heterocyclic dpp-iv inhibitors
|
|
WO2004032861A2
(en)
|
2002-10-11 |
2004-04-22 |
Bristol-Myers Squibb Company |
Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents
|
|
KR20050067418A
(ko)
|
2002-10-18 |
2005-07-01 |
머크 앤드 캄파니 인코포레이티드 |
당뇨병을 치료 또는 예방하기 위한 베타-아미노헤테로사이클릭 디펩티딜 펩티다제 억제제
|
|
US20040132732A1
(en)
|
2002-10-21 |
2004-07-08 |
Wei Han |
Quinazolinones and derivatives thereof as factor Xa inhibitors
|
|
DE60332856D1
(de)
|
2002-10-23 |
2010-07-15 |
Bristol Myers Squibb Co |
Auf glycinnitril basierende hemmer der dipeptidylpeptidase iv
|
|
WO2004041795A1
(en)
|
2002-10-30 |
2004-05-21 |
Guilford Pharmaceuticals Inc. |
Novel inhibitors of dipeptidyl peptidase iv
|
|
EP1562925B1
(en)
|
2002-11-07 |
2007-01-03 |
Merck & Co., Inc. |
Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
US7482337B2
(en)
|
2002-11-08 |
2009-01-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
EP1565437A1
(en)
|
2002-11-18 |
2005-08-24 |
Pfizer Products Inc. |
Dipeptidyl peptidase iv inhibiting fluorinated cyclic amides
|
|
DE10254304A1
(de)
|
2002-11-21 |
2004-06-03 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
AU2002952946A0
(en)
|
2002-11-27 |
2002-12-12 |
Fujisawa Pharmaceutical Co., Ltd. |
Dpp-iv inhibitor
|
|
UY28103A1
(es)
|
2002-12-03 |
2004-06-30 |
Boehringer Ingelheim Pharma |
Nuevas imidazo-piridinonas sustituidas, su preparación y su empleo como medicacmentos
|
|
US7109192B2
(en)
*
|
2002-12-03 |
2006-09-19 |
Boehringer Ingelheim Pharma Gmbh & Co Kg |
Substituted imidazo-pyridinones and imidazo-pyridazinones, the preparation thereof and their use as pharmaceutical compositions
|
|
AU2003297564A1
(en)
|
2002-12-04 |
2004-06-23 |
Merck & Co., Inc. |
Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
JP4279784B2
(ja)
|
2002-12-04 |
2009-06-17 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
１，３−ジヒドロ−イミダゾール縮合環化合物
|
|
US7420079B2
(en)
|
2002-12-09 |
2008-09-02 |
Bristol-Myers Squibb Company |
Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof
|
|
WO2004058266A1
(en)
|
2002-12-20 |
2004-07-15 |
Merck & Co., Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
WO2004062613A2
(en)
|
2003-01-13 |
2004-07-29 |
Bristol-Myers Squibb Company |
Hiv integrase inhibitors
|
|
WO2004064778A2
(en)
|
2003-01-17 |
2004-08-05 |
Merck & Co. Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
WO2004069162A2
(en)
|
2003-01-31 |
2004-08-19 |
Merck & Co., Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
PT1595866T
(pt)
|
2003-01-31 |
2016-09-14 |
Sanwa Kagaku Kenkyusho Co |
Cianopirrolidinas úteis para o tratamento entre outras de síndrome metabólica
|
|
WO2004071454A2
(en)
|
2003-02-13 |
2004-08-26 |
Guilford Pharmaceuticals Inc. |
Substituted azetidine compounds as inhibitors of dipeptidyl peptidase iv
|
|
US7148246B2
(en)
|
2003-02-27 |
2006-12-12 |
Sanofi-Aventis Deutschland Gmbh |
Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
|
|
DE10308356A1
(de)
|
2003-02-27 |
2004-09-09 |
Aventis Pharma Deutschland Gmbh |
Cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
|
|
DE10308351A1
(de)
|
2003-02-27 |
2004-11-25 |
Aventis Pharma Deutschland Gmbh |
1,3-substituierte Cycloalkylderivate mit sauren, meist heterocyclischen Gruppen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
DE10308353A1
(de)
|
2003-02-27 |
2004-12-02 |
Aventis Pharma Deutschland Gmbh |
Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
AU2003207881A1
(en)
|
2003-02-28 |
2004-09-17 |
Aic |
Dipeptidyl peptidase inhibitors
|
|
WO2004076434A1
(en)
|
2003-02-28 |
2004-09-10 |
Aic |
Dipeptidyl peptidase inhibitors
|
|
WO2004078777A2
(en)
|
2003-03-04 |
2004-09-16 |
Biorexis Pharmaceutical Corporation |
Dipeptidyl-peptidase protected proteins
|
|
AR043443A1
(es)
|
2003-03-07 |
2005-07-27 |
Merck & Co Inc |
Procedimiento de preparacion de tetrahidrotriazolopirazinas y productos intermedios
|
|
US20050014732A1
(en)
|
2003-03-14 |
2005-01-20 |
Pharmacia Corporation |
Combination of an aldosterone receptor antagonist and an anti-diabetic agent
|
|
AR043505A1
(es)
|
2003-03-18 |
2005-08-03 |
Merck & Co Inc |
Preparacion de beta-cetoamidas e intermediarios de reaccion
|
|
WO2004085661A2
(en)
|
2003-03-24 |
2004-10-07 |
Merck & Co., Inc |
Process to chiral beta-amino acid derivatives
|
|
US7550590B2
(en)
|
2003-03-25 |
2009-06-23 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
TWI357408B
(en)
|
2003-03-26 |
2012-02-01 |
Mitsubishi Tanabe Pharma Corp |
3-substituted-4-pyrimidone derivatives
|
|
JP2006521400A
(ja)
|
2003-03-26 |
2006-09-21 |
バイエル・フアーマシユーチカルズ・コーポレーシヨン |
糖尿病及び関連障害の処置のための化合物及びそれらの使用
|
|
WO2004087650A2
(en)
|
2003-03-27 |
2004-10-14 |
Merck & Co. Inc. |
Process and intermediates for the preparation of beta-amino acid amide dipeptidyl peptidase-iv inhibitors
|
|
WO2004089362A1
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
2-cyanopyrroles and their analogues as ddp-iv inhibitors
|
|
WO2004096806A1
(ja)
|
2003-04-30 |
2004-11-11 |
Sumitomo Pharmaceuticals Co. Ltd. |
縮合イミダゾール誘導体
|
|
JP5690463B2
(ja)
|
2003-05-05 |
2015-03-25 |
プロビオドルグ エージー |
グルタミニル、及びグルタミン酸シクラーゼのエフェクターの使用
|
|
JP4806628B2
(ja)
|
2003-05-05 |
2011-11-02 |
プロビオドルグ エージー |
グルタミニルシクラーゼ阻害剤
|
|
US20040229848A1
(en)
|
2003-05-05 |
2004-11-18 |
Hans-Ulrich Demuth |
Glutaminyl based DP IV-inhibitors
|
|
KR20110059664A
(ko)
|
2003-05-05 |
2011-06-02 |
프로비오드룩 아게 |
글루타미닐 및 글루타메이트 사이클라제의 이펙터의 용도
|
|
AU2003902260A0
(en)
|
2003-05-09 |
2003-05-29 |
Fujisawa Pharmaceutical Co., Ltd. |
Dpp-iv inhibitor
|
|
WO2004103993A1
(en)
|
2003-05-14 |
2004-12-02 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
|
WO2004103276A2
(en)
|
2003-05-14 |
2004-12-02 |
Merck & Co., Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
EP1627870A1
(en)
|
2003-05-15 |
2006-02-22 |
Taisho Pharmaceutical Co., Ltd |
Cyanofluoropyrrolidine derivative
|
|
EP1631680A2
(en)
|
2003-05-21 |
2006-03-08 |
Bayer HealthCare AG |
Diagnostics and therapeutics for diseases associated with dipeptidylpeptidase iv (dpp4)
|
|
WO2004104215A2
(en)
|
2003-05-21 |
2004-12-02 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with dipeptidylpeptidase 7 (dpp7)
|
|
WO2004110436A1
(en)
|
2003-06-06 |
2004-12-23 |
Merck & Co., Inc. |
Fused indoles as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
AU2003902946A0
(en)
|
2003-06-12 |
2003-06-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Dpp-iv inhibitor
|
|
CN1809544A
(zh)
|
2003-06-17 |
2006-07-26 |
麦克公司 |
作为二肽基肽酶抑制剂用于治疗或预防糖尿病的环己基甘氨酸衍生物
|
|
US7566707B2
(en)
|
2003-06-18 |
2009-07-28 |
Boehringer Ingelheim International Gmbh |
Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
DE10327439A1
(de)
|
2003-06-18 |
2005-01-05 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Imidazopyridazinon- und Imidazopyridonderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
ES2355105T3
(es)
|
2003-06-20 |
2011-03-22 |
F. Hoffmann-La Roche Ag |
Pirido(2,1-a)isoquinolina como inhibidores de la dpp-iv.
|
|
RU2339636C2
(ru)
|
2003-06-20 |
2008-11-27 |
Ф.Хоффманн-Ля Рош Аг |
Гексагидропиридоизохинолины в качестве ингибиторов дипептидилпептидазы iv (dpp-iv)
|
|
JO2625B1
(en)
*
|
2003-06-24 |
2011-11-01 |
ميرك شارب اند دوم كوربوريشن |
Phosphoric acid salts of dipeptidyl betidase inhibitor 4
|
|
DE10330842A1
(de)
|
2003-07-08 |
2005-02-10 |
Institut für Medizintechnologie Magdeburg GmbH, IMTM |
Verwendung der Inhibitoren von Enzymen mit Aktivitäten der Aminopeptidase N und/oder der Dipeptidylpeptidase IV und pharmazeutischen Zubereitungen daraus zur Therapie und Prävention dermatologischer Erkrankungen mit Hyperproliferation und veränderten Differenzierungszuständen von Fibroblasten
|
|
AU2004261186A1
(en)
|
2003-07-31 |
2005-02-10 |
Merck & Co., Inc. |
Hexahydrodiazepinones as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
|
US6995183B2
(en)
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
KR20060041309A
(ko)
|
2003-08-13 |
2006-05-11 |
다케다 야쿠힌 고교 가부시키가이샤 |
４-피리미돈 유도체 및 펩티딜 펩티다제 저해제로서의 그의용도
|
|
WO2005019168A2
(en)
|
2003-08-20 |
2005-03-03 |
Pfizer Products Inc. |
Fluorinated lysine derivatives as dipeptidyl peptidase iv inhibitors
|
|
US7790734B2
(en)
*
|
2003-09-08 |
2010-09-07 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
WO2005030751A2
(en)
*
|
2003-09-08 |
2005-04-07 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
EP1532980A1
(en)
|
2003-11-24 |
2005-05-25 |
Novo Nordisk A/S |
N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes
|
|
US7304086B2
(en)
|
2004-02-05 |
2007-12-04 |
Probiodrug Ag |
Inhibitors of glutaminyl cyclase
|
|
CN102127057A
(zh)
*
|
2004-03-15 |
2011-07-20 |
武田药品工业株式会社 |
二肽基肽酶抑制剂
|
|
WO2006068978A2
(en)
|
2004-12-21 |
2006-06-29 |
Takeda Pharmaceutial Company Limited |
Dipeptidyl peptidase inhibitors
|
|
PL1931350T5
(pl)
|
2005-09-14 |
2021-11-15 |
Takeda Pharmaceutical Company Limited |
Podanie inhibitorów dipeptydylo-peptydazy
|
|
GEP20135838B
(en)
*
|
2005-09-14 |
2013-06-10 |
Takeda Pharmaceutical |
Dipeptidyl peptidase inhibitors usage at diabetes treatment
|
|
EP2073810B1
(en)
*
|
2006-09-13 |
2011-08-31 |
Takeda Pharmaceutical Company Limited |
Use of 2-6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2h-pyrimidin-1-ylmethyl-4-fluoro-benzonitrile for treating diabetes, cancer, autoimmune disorders and hiv infection
|
|
PE20070622A1
(es)
|
2005-09-14 |
2007-08-22 |
Takeda Pharmaceutical |
Administracion de inhibidores de dipeptidil peptidasa
|
|
CN101360723A
(zh)
*
|
2005-09-16 |
2009-02-04 |
武田药品工业株式会社 |
制备嘧啶二酮衍生物的方法
|
|
TW200745079A
(en)
|
2005-09-16 |
2007-12-16 |
Takeda Pharmaceuticals Co |
Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
|
|
EP1999108A1
(en)
*
|
2006-03-28 |
2008-12-10 |
Takeda Pharmaceutical Company Limited |
Preparation of (r)-3-aminopiperidine dihydrochloride
|
|
TW200838536A
(en)
*
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|