MXPA03000772A - Derivados de acido hexahidro-7-1h-azepin-2-il-hexanoico como inhibidores de oxido nitrico sintasa inducible. - Google Patents

Derivados de acido hexahidro-7-1h-azepin-2-il-hexanoico como inhibidores de oxido nitrico sintasa inducible.

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Publication number
MXPA03000772A
MXPA03000772A MXPA03000772A MXPA03000772A MXPA03000772A MX PA03000772 A MXPA03000772 A MX PA03000772A MX PA03000772 A MXPA03000772 A MX PA03000772A MX PA03000772 A MXPA03000772 A MX PA03000772A MX PA03000772 A MXPA03000772 A MX PA03000772A
Authority
MX
Mexico
Prior art keywords
azepin
hexahydro
inhibitors
acid derivatives
nitric oxide
Prior art date
Application number
MXPA03000772A
Other languages
English (en)
Inventor
Donald W Hansen
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of MXPA03000772A publication Critical patent/MXPA03000772A/es

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    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12Nitrogen atoms not forming part of a nitro radical
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    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D223/10Oxygen atoms attached in position 2

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MXPA03000772A 2000-08-01 2001-08-01 Derivados de acido hexahidro-7-1h-azepin-2-il-hexanoico como inhibidores de oxido nitrico sintasa inducible. MXPA03000772A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22217900P 2000-08-01 2000-08-01
PCT/US2001/024542 WO2002010139A1 (en) 2000-08-01 2001-08-01 Hexahydro-7-1h-azepin-2-yl-haxanoic acid derivatives as inhibitors of inducible nitric oxide synthase

Publications (1)

Publication Number Publication Date
MXPA03000772A true MXPA03000772A (es) 2003-06-04

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Application Number Title Priority Date Filing Date
MXPA03000772A MXPA03000772A (es) 2000-08-01 2001-08-01 Derivados de acido hexahidro-7-1h-azepin-2-il-hexanoico como inhibidores de oxido nitrico sintasa inducible.

Country Status (11)

Country Link
US (1) US6495544B2 (es)
EP (1) EP1305293A1 (es)
JP (1) JP2004512271A (es)
AR (1) AR032360A1 (es)
AU (1) AU2001281083A1 (es)
CA (1) CA2415851A1 (es)
EA (1) EA005817B1 (es)
MX (1) MXPA03000772A (es)
NZ (1) NZ523770A (es)
PE (1) PE20030413A1 (es)
WO (1) WO2002010139A1 (es)

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US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7718644B2 (en) 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
KR20050004155A (ko) * 2002-05-16 2005-01-12 파마시아 코포레이션 선택적 유도성 산화질소 신타아제 억제제를 이용한 호흡기질병 및 질환의 치료 방법
US7544678B2 (en) 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
WO2004062575A2 (en) * 2003-01-07 2004-07-29 Kemin Pharma Europe Bvba Bicyclic carbohydrate compounds useful in the treatment of infections caused by flaviviridae sp., such as hepatitis c and bovine viral diarrhea viruses
AU2004220548A1 (en) 2003-03-07 2004-09-23 The Trustees Of Columbia University, In The City Of New York Type 1 ryanodine receptor-based methods
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US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
CN102127053A (zh) * 2004-03-15 2011-07-20 武田药品工业株式会社 二肽基肽酶抑制剂
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