AU2001271531A1 - Fatty acid synthase inhibitors - Google Patents

Fatty acid synthase inhibitors

Info

Publication number
AU2001271531A1
AU2001271531A1 AU2001271531A AU7153101A AU2001271531A1 AU 2001271531 A1 AU2001271531 A1 AU 2001271531A1 AU 2001271531 A AU2001271531 A AU 2001271531A AU 7153101 A AU7153101 A AU 7153101A AU 2001271531 A1 AU2001271531 A1 AU 2001271531A1
Authority
AU
Australia
Prior art keywords
fatty acid
acid synthase
synthase inhibitors
inhibitors
fatty
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001271531A
Inventor
Siegfried B. Christensen Iv
Robert A Daines
Martha S. Head
Jack D. Leber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of AU2001271531A1 publication Critical patent/AU2001271531A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001271531A 2000-06-27 2001-06-27 Fatty acid synthase inhibitors Abandoned AU2001271531A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21458600P 2000-06-27 2000-06-27
US60214586 2000-06-27
PCT/US2001/020475 WO2002000620A1 (en) 2000-06-27 2001-06-27 Fatty acid synthase inhibitors

Publications (1)

Publication Number Publication Date
AU2001271531A1 true AU2001271531A1 (en) 2002-01-08

Family

ID=22799651

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001271531A Abandoned AU2001271531A1 (en) 2000-06-27 2001-06-27 Fatty acid synthase inhibitors

Country Status (3)

Country Link
US (1) US6670388B1 (en)
AU (1) AU2001271531A1 (en)
WO (1) WO2002000620A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1242075A4 (en) * 1999-10-22 2002-12-04 Smithkline Beecham Corp Indole compounds
AU2004261667A1 (en) * 2003-08-01 2005-02-10 Genelabs Technologies, Inc. Bicyclic imidazol derivatives against Flaviviridae
US20060211698A1 (en) * 2005-01-14 2006-09-21 Genelabs, Inc. Bicyclic heteroaryl derivatives for treating viruses
CN101117328B (en) * 2006-08-01 2012-11-07 中国人民解放军军事医学科学院毒物药物研究所 Fatty acid synthetase inhibitor and application for treating bacterial infection
US8450350B2 (en) 2010-05-05 2013-05-28 Infinity Pharmaceuticals, Inc. Triazoles as inhibitors of fatty acid synthase
WO2011140190A1 (en) 2010-05-05 2011-11-10 Infinity Pharmaceuticals Tetrazolones as inhibitors of fatty acid synthase
AU2014249003A1 (en) 2013-03-13 2015-10-15 Forma Therapeutics, Inc. Novel compounds and compositions for inhibition of FASN
TWI767148B (en) 2018-10-10 2022-06-11 美商弗瑪治療公司 Inhibiting fatty acid synthase (fasn)
US10793554B2 (en) 2018-10-29 2020-10-06 Forma Therapeutics, Inc. Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684032A (en) 1994-12-13 1997-11-04 Smithkline Beecham Corporation Compounds
EP1021181A4 (en) * 1996-03-28 2002-06-26 Smithkline Beecham Corp Carboxylic acid indole inhibitors of chemokines
CA2264020A1 (en) * 1996-08-26 1998-03-05 Jean Bemis Inhibitors of phospholipase enzymes
ATE293599T1 (en) 1997-12-24 2005-05-15 Aventis Pharma Gmbh INDOLE DERIVATIVES AS FACTOR XA INHIBITORS
EE200000522A (en) * 1998-02-25 2002-02-15 Genetics Institute, Inc. Phospholipase A2 Enzyme Inhibitor, a Pharmaceutical Composition Containing It and a Method for Inhibiting the Phospholipase Enzyme Activity

Also Published As

Publication number Publication date
US6670388B1 (en) 2003-12-30
WO2002000620A1 (en) 2002-01-03

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