AU2002222252A1 - Nitric oxide synthase inhibitor phosphate salt - Google Patents

Nitric oxide synthase inhibitor phosphate salt

Info

Publication number
AU2002222252A1
AU2002222252A1 AU2002222252A AU2002222252A AU2002222252A1 AU 2002222252 A1 AU2002222252 A1 AU 2002222252A1 AU 2002222252 A AU2002222252 A AU 2002222252A AU 2002222252 A AU2002222252 A AU 2002222252A AU 2002222252 A1 AU2002222252 A1 AU 2002222252A1
Authority
AU
Australia
Prior art keywords
nitric oxide
phosphate salt
oxide synthase
synthase inhibitor
inhibitor phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002222252A
Other versions
AU2002222252B2 (en
Inventor
David Box
David Colclough
Iain Gillies
Michael Simon Loft
Rebecca Moore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0031179.5A external-priority patent/GB0031179D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AU2002222252A1 publication Critical patent/AU2002222252A1/en
Application granted granted Critical
Publication of AU2002222252B2 publication Critical patent/AU2002222252B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002222252A 2000-12-21 2001-12-17 Nitric oxide synthase inhibitor phosphate salt Ceased AU2002222252B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0031179.5 2000-12-21
GBGB0031179.5A GB0031179D0 (en) 2000-12-21 2000-12-21 Nitric oxide synthase inhibitors
PCT/GB2001/005596 WO2002050021A1 (en) 2000-12-21 2001-12-17 Nitric oxide synthase inhibitor phosphate salt

Publications (2)

Publication Number Publication Date
AU2002222252A1 true AU2002222252A1 (en) 2002-09-05
AU2002222252B2 AU2002222252B2 (en) 2005-02-24

Family

ID=9905536

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2002222252A Ceased AU2002222252B2 (en) 2000-12-21 2001-12-17 Nitric oxide synthase inhibitor phosphate salt
AU2225202A Pending AU2225202A (en) 2000-12-21 2001-12-17 Nitric oxide synthase inhibitor phosphate salt

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2225202A Pending AU2225202A (en) 2000-12-21 2001-12-17 Nitric oxide synthase inhibitor phosphate salt

Country Status (19)

Country Link
US (1) US7317040B2 (en)
EP (1) EP1351929A1 (en)
JP (1) JP3971704B2 (en)
KR (1) KR100853049B1 (en)
CN (1) CN100369894C (en)
AR (1) AR031944A1 (en)
AU (2) AU2002222252B2 (en)
BR (1) BR0116369A (en)
CA (1) CA2432121C (en)
CZ (1) CZ301458B6 (en)
GB (1) GB0031179D0 (en)
HU (1) HUP0500736A3 (en)
IL (1) IL156305A0 (en)
MX (1) MXPA03005698A (en)
NO (1) NO328982B1 (en)
NZ (1) NZ526563A (en)
PL (1) PL207158B1 (en)
WO (1) WO2002050021A1 (en)
ZA (1) ZA200304683B (en)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0214147D0 (en) * 2002-06-19 2002-07-31 Glaxo Group Ltd Formulations
AU2003258327B2 (en) * 2002-08-23 2009-05-21 Pharmacia Corporation Crystalline solid form of (2S-5Z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid
TWI328009B (en) 2003-05-21 2010-08-01 Glaxo Group Ltd Quinoline derivatives as phosphodiesterase inhibitors
GB0316290D0 (en) 2003-07-11 2003-08-13 Glaxo Group Ltd Novel compounds
PE20060272A1 (en) 2004-05-24 2006-05-22 Glaxo Group Ltd (2R, 3R, 4S, 5R, 2'R, 3'R, 4'S, 5'S) -2.2 '- {TRANS-1,4-CYCLOHEXANODIYLBIS- [IMINO (2 - {[2- (1-METHYL- 1H-IMIDAZOL-4-IL) ETHYL] AMINO} -9H-PURIN-6,9-DIYL)]} BIS [5- (2-ETHYL-2H-TETRAZOLE-5-IL) TETRAHYDRO-3,4-FURANODIOL] AS AN A2A AGONIST
TWI307630B (en) 2004-07-01 2009-03-21 Glaxo Group Ltd Immunoglobulins
GB0418045D0 (en) 2004-08-12 2004-09-15 Glaxo Group Ltd Compounds
EP1841780B1 (en) 2005-01-10 2011-07-27 Glaxo Group Limited Androstane 17-alpha-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
PE20100741A1 (en) 2005-03-25 2010-11-25 Glaxo Group Ltd COMPOUNDS DERIVED FROM 3,4-DIHYDROPYRIMIDE [4,5-d] PYRIMIDIN-2 (1H) -ONE AS KINASE INHIBITORS p38
TWI389690B (en) 2005-03-25 2013-03-21 Glaxo Group Ltd Novel compounds
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
TW200730498A (en) 2005-12-20 2007-08-16 Glaxo Group Ltd Compounds
US7943651B2 (en) 2006-04-20 2011-05-17 Glaxo Group Limited Compounds
GB0611587D0 (en) 2006-06-12 2006-07-19 Glaxo Group Ltd Novel compounds
SI2046787T1 (en) 2006-08-01 2011-07-29 Glaxo Group Ltd PYRAZOLO?á3,4-B?åPYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS
US20080114021A1 (en) * 2006-11-09 2008-05-15 University Of Maryland Baltimore Use Of 5,6-Dimethylxanthenone-4-Acetic Acid as an Antimicrobial Agent
AR065804A1 (en) 2007-03-23 2009-07-01 Smithkline Beecham Corp COMPOSITE OF INDOL CARBOXAMIDE, PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS IT AND USE OF THIS COMPOUND TO PREPARE A MEDICINAL PRODUCT
MX2010012814A (en) 2008-05-23 2010-12-20 Amira Pharmaceuticals Inc 5-lipoxygenase-activating protein inhibitor.
ES2383246T3 (en) 2008-06-05 2012-06-19 Glaxo Group Limited 4-amino-indazoles
ES2566339T3 (en) 2008-06-05 2016-04-12 Glaxo Group Limited 4-Carboxamide indazole derivatives useful as PI3-kinase inhibitors
WO2010094643A1 (en) 2009-02-17 2010-08-26 Glaxo Group Limited Quinoline derivatives and their uses for rhinitis and urticaria
WO2010102958A1 (en) 2009-03-09 2010-09-16 Glaxo Group Limited 4-oxadiazol-2 -yl- indazoles as inhibitors of p13 kinases
EP2406249A1 (en) 2009-03-10 2012-01-18 Glaxo Group Limited Indole derivatives as ikk2 inhibitors
WO2010106016A1 (en) 2009-03-17 2010-09-23 Glaxo Group Limited Pyrimidine derivatives used as itk inhibitors
EP2408458A1 (en) 2009-03-19 2012-01-25 Merck Sharp&Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 (STAT6) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
EP2408915A2 (en) 2009-03-19 2012-01-25 Merck Sharp&Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF GATA BINDING PROTEIN 3 (GATA3) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
MX2011009724A (en) 2009-03-19 2011-10-14 Merck Sharp & Dohme RNA INTERFERENCE MEDIATED INHIBITION OF BTB AND CNC HOMOLOGY 1, BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR 1 (BACH 1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) SEQUENCE LISTING.
EP2408916A2 (en) 2009-03-19 2012-01-25 Merck Sharp&Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2010111471A2 (en) 2009-03-27 2010-09-30 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
EP2411520A2 (en) 2009-03-27 2012-02-01 Merck Sharp&Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF THE THYMIC STROMAL LYMPHOPOIETIN (TSLP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
JP2012521765A (en) 2009-03-27 2012-09-20 メルク・シャープ・エンド・ドーム・コーポレイション RNA interference-mediated inhibition of intracellular adhesion molecule 1 (ICAM-1) gene expression using small interfering nucleic acids (siNA)
US20120004281A1 (en) 2009-03-27 2012-01-05 Merck Sharp & Dohme Corp RNA Interference Mediated Inhibition of the Nerve Growth Factor Beta Chain (NGFB) Gene Expression Using Short Interfering Nucleic Acid (siNA)
WO2010111464A1 (en) 2009-03-27 2010-09-30 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
US20100273744A1 (en) 2009-04-24 2010-10-28 Paul Martin Gore Compounds
WO2010122088A1 (en) 2009-04-24 2010-10-28 Glaxo Group Limited Pyrazole and triazole carboxamides as crac channel inhibitors
BRPI1016219B8 (en) 2009-04-30 2021-05-25 Glaxo Group Ltd indazole compound substituted with oxazole, and pharmaceutical composition
WO2011067366A1 (en) 2009-12-03 2011-06-09 Glaxo Group Limited Indazole derivatives as pi 3 - kinase inhibitors
WO2011067364A1 (en) 2009-12-03 2011-06-09 Glaxo Group Limited Novel compounds
JP2013512879A (en) 2009-12-03 2013-04-18 グラクソ グループ リミテッド Benzpyrazole derivatives as inhibitors of PI3 kinase
EP2512438B1 (en) 2009-12-16 2017-01-25 3M Innovative Properties Company Formulations and methods for controlling mdi particle size delivery
TWI375671B (en) * 2010-03-01 2012-11-01 Univ China Medical Pharmaceutical compositions containing brazilin for inhibiting expression of cytokines of t helper cell type ii and/or inhibiting expression of chemokines and uses of the same
WO2011110575A1 (en) 2010-03-11 2011-09-15 Glaxo Group Limited Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
GB201007203D0 (en) 2010-04-29 2010-06-16 Glaxo Group Ltd Novel compounds
PL2614058T3 (en) 2010-09-08 2015-12-31 Glaxosmithkline Ip Dev Ltd POLYMORPHS AND SALTS OF N-[5-[4-(5-{[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]METHYL}-& xA;1,3-OXAZOL-2-YL)-1H-INDAZOL-6-YL]-2-(METHYLOXY)-3-PYRIDINYL]METHANESULFONAMIDE
ES2602972T3 (en) 2010-09-08 2017-02-23 Glaxosmithkline Intellectual Property Development Limited Indazole derivatives for use in the treatment of influenza virus infection
WO2012035055A1 (en) 2010-09-17 2012-03-22 Glaxo Group Limited Novel compounds
ES2532213T3 (en) 2010-10-21 2015-03-25 Glaxo Group Limited Pyrazole compounds that act against allergic, immune and inflammatory conditions
WO2012052459A1 (en) 2010-10-21 2012-04-26 Glaxo Group Limited Pyrazole compounds acting against allergic, inflammatory and immune disorders
GB201018124D0 (en) 2010-10-27 2010-12-08 Glaxo Group Ltd Polymorphs and salts
JP2012140390A (en) * 2011-01-06 2012-07-26 Sumitomo Chemical Co Ltd METHOD FOR PRODUCING α-AMINO-γ-BUTYROLACTONE
GB201104153D0 (en) 2011-03-11 2011-04-27 Glaxo Group Ltd Novel compounds
EP2683716A1 (en) 2011-03-11 2014-01-15 Glaxo Group Limited Pyrido[3,4-b]pyrazine derivatives as syk inhibitors
CN102344397B (en) * 2011-08-23 2013-09-04 浙江升华拜克生物股份有限公司 Method for purifying valnemulin hydrochloride
KR20160060100A (en) 2013-09-22 2016-05-27 칼리토르 사이언시즈, 엘엘씨 Substituted aminopyrimidine compounds and methods of use
EP3122730B1 (en) 2014-03-28 2020-03-25 Calitor Sciences, LLC Substituted heteroaryl compounds and methods of use
WO2015173701A2 (en) 2014-05-12 2015-11-19 Glaxosmithkline Intellectual Property (No. 2) Limited Pharmaceutical compositions for treating infectious diseases
EP3347097B1 (en) 2015-09-11 2021-02-24 Sunshine Lake Pharma Co., Ltd. Substituted aminopyrimidine derivatives as modulators of the kinases jak, flt3 and aurora
WO2017214159A1 (en) 2016-06-06 2017-12-14 The Regents Of The University Of California A host cell modified to produce lactams
WO2019099311A1 (en) 2017-11-19 2019-05-23 Sunshine Lake Pharma Co., Ltd. Substituted heteroaryl compounds and methods of use
EP3740468A4 (en) 2018-01-20 2021-10-06 Sunshine Lake Pharma Co., Ltd. Substituted aminopyrimidine compounds and methods of use
CN109369432B (en) * 2018-11-02 2021-06-25 永农生物科学有限公司 Preparation method of (S) -4-chloro-2-aminobutyrate
EP4125919A1 (en) 2020-03-26 2023-02-08 GlaxoSmithKline Intellectual Property Development Limited Cathepsin inhibitors for preventing or treating viral infections

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE191470T1 (en) 1994-06-15 2000-04-15 Wellcome Found ENZYME INHIBITORS
ES2151075T3 (en) 1994-07-04 2000-12-16 Schering Ag LOW DOSE STEROID TABLETS, CONTAINING GALIC ACID ESTERS AS AN ANTIOXIDANT, PROCESS FOR ITS MANUFACTURE AND USE.
MY117948A (en) * 1997-01-13 2004-08-30 Glaxo Group Ltd Nitride oxide synthase inhibitors.
ATE277894T1 (en) 1998-03-11 2004-10-15 Searle & Co HALOGENATED AMINO ACID DERIVATIVES AS INHIBITORS OF NITROGEN MONOXIDE SYNTHASE
GB9810299D0 (en) 1998-05-15 1998-07-15 Glaxo Group Ltd Use of nitric oxide synthase inhibitors

Similar Documents

Publication Publication Date Title
AU2002222252A1 (en) Nitric oxide synthase inhibitor phosphate salt
AU2225202A (en) Nitric oxide synthase inhibitor phosphate salt
AU4430599A (en) Inhibitors of nitric oxide synthase
HK1034241A1 (en) Nitric oxide synthase inhibitors
AU4774501A (en) Amidino compounds useful as nitric oxide synthase inhibitors
AU2001258771A1 (en) -secretase inhibitors
AP9901603A0 (en) Nitric oxide synthase inhibitors
AU2625201A (en) Glycogen synthase kinase-3 inhibitors
AU2002213048A1 (en) Phosphate transport inhibitors
ZA991894B (en) Halogenated amidino amino acid derivatives useful as nitric oxide synthase inhibitors.
AU2001236052A1 (en) Urease inhibitors
AU2001259354A1 (en) Phosphate transport inhibitors
IL153230A0 (en) Liposomal benzoquinazoline thymidylate synthase inhibitor formulations
AU2001270200A1 (en) Fatty acid synthase inhibitors
AU2001281059A1 (en) Fatty acid synthase inhibitors
AU2002224550A1 (en) Corrosion inhibitors
AU2001282746A1 (en) Novel phenylheteroazetidines, useful as nitric oxide synthase inhibitors
AU2001271531A1 (en) Fatty acid synthase inhibitors
GB9810299D0 (en) Use of nitric oxide synthase inhibitors
AU2002350575A1 (en) Selective neuronal nitric oxide synthase inhibitors
AU2002243439A1 (en) Fatty acid synthase inhibitors
AU1539399A (en) Inhibitors of nitric oxide synthase
AU2001271718A1 (en) Fatty acid synthase inhibitors
AU2001284705A1 (en) Fatty acid synthase inhibitors
AU2001291160A1 (en) Fatty acid synthase inhibitors