|
US6982260B1
(en)
|
1999-11-22 |
2006-01-03 |
Warner-Lambert Company |
Quinazolines and their use for inhibiting cyclin-dependent kinase enzymes
|
|
US6660731B2
(en)
*
|
2000-09-15 |
2003-12-09 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
US7473691B2
(en)
*
|
2000-09-15 |
2009-01-06 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
EP1317450B1
(en)
*
|
2000-09-15 |
2006-11-22 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
US20020111353A1
(en)
*
|
2000-12-05 |
2002-08-15 |
Mark Ledeboer |
Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases
|
|
NZ526472A
(en)
*
|
2000-12-21 |
2004-04-30 |
Vertex Pharma |
Pyrazole compounds useful as protein kinase inhibitors
|
|
US20030125344A1
(en)
*
|
2001-03-23 |
2003-07-03 |
Bayer Corporation |
Rho-kinase inhibitors
|
|
US7034026B2
(en)
|
2001-04-10 |
2006-04-25 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
|
US7105667B2
(en)
*
|
2001-05-01 |
2006-09-12 |
Bristol-Myers Squibb Co. |
Fused heterocyclic compounds and use thereof
|
|
US7138404B2
(en)
*
|
2001-05-23 |
2006-11-21 |
Hoffmann-La Roche Inc. |
4-aminopyrimidine derivatives
|
|
US7115617B2
(en)
|
2001-08-22 |
2006-10-03 |
Amgen Inc. |
Amino-substituted pyrimidinyl derivatives and methods of use
|
|
US6939874B2
(en)
|
2001-08-22 |
2005-09-06 |
Amgen Inc. |
Substituted pyrimidinyl derivatives and methods of use
|
|
WO2003028720A1
(en)
|
2001-09-26 |
2003-04-10 |
Pharmacia Italia S.P.A. |
Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
|
|
WO2003026664A1
(en)
*
|
2001-09-26 |
2003-04-03 |
Bayer Corporation |
2-phenylamino-4- (5-pyrazolylamino) -pyramidine derivatives as kinase inhibitors, in particular, src kinase inhibitors
|
|
SE0104140D0
(sv)
|
2001-12-07 |
2001-12-07 |
Astrazeneca Ab |
Novel Compounds
|
|
US20030187026A1
(en)
|
2001-12-13 |
2003-10-02 |
Qun Li |
Kinase inhibitors
|
|
AU2002361846A1
(en)
*
|
2001-12-21 |
2003-07-15 |
Bayer Pharmaceuticals Corporation |
Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
|
|
AU2003235798A1
(en)
|
2002-01-10 |
2003-07-24 |
F. Hoffmann-La Roche Ag |
Use of a gsk-3beta inhibitor in the manufacture of a medicament for increasing bone formation
|
|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
EP1472245A2
(en)
*
|
2002-02-06 |
2004-11-03 |
Vertex Pharmaceuticals Incorporated |
Heteroaryl compounds useful as inhibitors of gsk-3
|
|
EP1485100B1
(en)
|
2002-03-15 |
2010-05-05 |
Vertex Pharmaceuticals Incorporated |
Azinylaminoazoles as inhibitors of protein kinases
|
|
DE60327999D1
(de)
|
2002-03-15 |
2009-07-30 |
Vertex Pharma |
Azolylaminoazine als inhibitoren von proteinkinasen
|
|
AU2003218215A1
(en)
|
2002-03-15 |
2003-09-29 |
Vertex Pharmaceuticals, Inc. |
Azolylaminoazines as inhibitors of protein kinases
|
|
US7223738B2
(en)
|
2002-04-08 |
2007-05-29 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
|
AU2003242252A1
(en)
|
2002-06-07 |
2003-12-22 |
Kyowa Hakko Kogyo Co., Ltd. |
Bicyclic pyrimidine derivatives
|
|
MY141867A
(en)
|
2002-06-20 |
2010-07-16 |
Vertex Pharma |
Substituted pyrimidines useful as protein kinase inhibitors
|
|
JP2005536517A
(ja)
*
|
2002-07-23 |
2005-12-02 |
スミスクライン ビーチャム コーポレーション |
キナーゼインヒビターとしてのピラゾロピリミジン
|
|
ES2445208T3
(es)
|
2002-07-29 |
2014-02-28 |
Rigel Pharmaceuticals, Inc. |
Compuestos de 2,4-pirimidindiamina para uso en métodos para tratar o prevenir enfermedades autoinmunitarias
|
|
EP1739087A1
(en)
*
|
2002-08-02 |
2007-01-03 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compositions useful as inhibitors of gsk-3
|
|
DK1532145T3
(da)
*
|
2002-08-02 |
2007-01-15 |
Vertex Pharma |
Pyrazolpræparater der er anvendelige som inhibitorer af GSK-3
|
|
BR0314098A
(pt)
*
|
2002-09-05 |
2005-07-19 |
Aventis Pharma Sa |
Derivados da aminoindazóis a tìtulo de medicamentos e composições farmacêuticas que os contêm
|
|
FR2844267B1
(fr)
*
|
2002-09-05 |
2008-02-15 |
Aventis Pharma Sa |
Nouveaux derives d'aminoindazoles a titre de medicaments et compositions pharmaceutiques les renfermant
|
|
AU2003255482A1
(en)
*
|
2002-10-02 |
2004-04-23 |
Merck Patent Gmbh |
Use of 4 amino-quinazolines as anti cancer agents
|
|
MXPA05003607A
(es)
|
2002-10-04 |
2005-11-17 |
Prana Biotechnology Ltd |
Compuestos neurologicamente activos.
|
|
KR100490893B1
(ko)
*
|
2002-10-11 |
2005-05-23 |
(주) 비엔씨바이오팜 |
2-메톡시-1,3,5-트리아진 유도체, 그 제조방법 및 이를 포함하는 항바이러스용 약학적 조성물
|
|
GB0226583D0
(en)
*
|
2002-11-14 |
2002-12-18 |
Cyclacel Ltd |
Compounds
|
|
US7309701B2
(en)
|
2002-11-19 |
2007-12-18 |
Sanofi-Aventis Deutschland Gmbh |
Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them
|
|
US7462613B2
(en)
|
2002-11-19 |
2008-12-09 |
Sanofi-Aventis Deutschland Gmbh |
Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them
|
|
FR2847253B1
(fr)
*
|
2002-11-19 |
2007-05-18 |
Aventis Pharma Sa |
Nouveaux derives de pyridazinones a titre de medicaments et compositions pharmaceutiques les renfermant
|
|
US7423148B2
(en)
*
|
2002-11-21 |
2008-09-09 |
Chiron Corporation |
Small molecule PI 3-kinase inhibitors and methods of their use
|
|
WO2004072029A2
(en)
*
|
2003-02-06 |
2004-08-26 |
Vertex Pharmaceuticals Incorporated |
Pyrazolopyridazines useful as inhibitors of protein kinases
|
|
US7157455B2
(en)
*
|
2003-02-10 |
2007-01-02 |
Hoffmann-La Roche Inc. |
4-Aminopyrimidine-5-one derivatives
|
|
WO2004087679A1
(en)
*
|
2003-04-01 |
2004-10-14 |
Aponetics Ag |
2, 4, 6-trisubstituted pyrimidine derivatives useful for the treatment of neoplastic and autoimmune diseases
|
|
ATE401080T1
(de)
*
|
2003-06-02 |
2008-08-15 |
Astrazeneca Ab |
(3-((chinazolin-4-yl)amino)-1h-pyrazol-1- yl)acetamid derivate und verwandte verbindungen als aurora kinase inhibitoren zur behandlung von proliferativen erkrankungen wie krebs
|
|
JP4869068B2
(ja)
*
|
2003-06-19 |
2012-02-01 |
スミスクライン ビーチャム コーポレーション |
化合物
|
|
TWI372050B
(en)
*
|
2003-07-03 |
2012-09-11 |
Astex Therapeutics Ltd |
(morpholin-4-ylmethyl-1h-benzimidazol-2-yl)-1h-pyrazoles
|
|
US8309562B2
(en)
|
2003-07-03 |
2012-11-13 |
Myrexis, Inc. |
Compounds and therapeutical use thereof
|
|
NZ544472A
(en)
|
2003-07-03 |
2009-04-30 |
Myriad Genetics Inc |
Compounds and therapeutical use thereof
|
|
GB0315966D0
(en)
*
|
2003-07-08 |
2003-08-13 |
Cyclacel Ltd |
Compounds
|
|
PL2256106T3
(pl)
|
2003-07-22 |
2015-08-31 |
Astex Therapeutics Ltd |
Związki 3,4-pochodne 1h-pirazolu i ich zastosowanie jako kinazy zależne od cyklin (cdk) i modulatory kinazy syntazy glikogenu-3 (gsk-3)
|
|
EP1648875A1
(en)
*
|
2003-07-30 |
2006-04-26 |
Cyclacel Limited |
2-aminophenyl-4-phenylpyrimidines as kinase inhibitors
|
|
BRPI0413018B8
(pt)
|
2003-07-30 |
2021-05-25 |
Rigel Pharmaceuticals Inc |
composto, e, uso de um composto
|
|
US7417726B2
(en)
*
|
2003-09-19 |
2008-08-26 |
Applied Biosystems Inc. |
Normalization of data using controls
|
|
US20060024690A1
(en)
*
|
2003-09-19 |
2006-02-02 |
Kao H P |
Normalization of data using controls
|
|
US20050221357A1
(en)
*
|
2003-09-19 |
2005-10-06 |
Mark Shannon |
Normalization of gene expression data
|
|
WO2005030131A2
(en)
*
|
2003-09-23 |
2005-04-07 |
Replidyne, Inc |
Bis-quinazoline compounds for the treatment of bacterial infections
|
|
WO2005040159A1
(en)
|
2003-10-17 |
2005-05-06 |
Astrazeneca Ab |
4-(pyrazol-3-ylamino) pyrimidine derivatives for use in the treatment of cancer
|
|
AU2004297235A1
(en)
*
|
2003-12-04 |
2005-06-23 |
Vertex Pharmaceuticals Incorporated |
Quinoxalines useful as inhibitors of protein kinases
|
|
RU2006124559A
(ru)
*
|
2003-12-09 |
2008-01-20 |
Вертекс Фармасьютикалз Инкорпорейтед (Us) |
Производные нафтиридина и применение указанных производныхых в качестве модуляторов мускариновых рецепторов
|
|
WO2005061519A1
(en)
|
2003-12-19 |
2005-07-07 |
Takeda San Diego, Inc. |
Kinase inhibitors
|
|
TW200530235A
(en)
|
2003-12-24 |
2005-09-16 |
Renovis Inc |
Bicycloheteroarylamine compounds as ion channel ligands and uses thereof
|
|
JP2007522233A
(ja)
*
|
2004-02-11 |
2007-08-09 |
アムジエン・インコーポレーテツド |
バニロイド受容体リガンド及び治療におけるそれらの使用
|
|
US20080050314A1
(en)
*
|
2004-02-26 |
2008-02-28 |
Bayer Healthcare Ag |
Diagnostics and Therapeutics for Diseases Associated With Glycogen Synthase Kinase 3 Beta (Gsk3b)
|
|
US7786165B2
(en)
*
|
2004-03-15 |
2010-08-31 |
Takeda Pharmaceutical Company Limited |
Aminophenylpropanoic acid derivative
|
|
WO2005099688A2
(en)
*
|
2004-04-07 |
2005-10-27 |
Takeda Pharmaceutical Company Limited |
Cyclic compounds
|
|
EP1742921A2
(en)
*
|
2004-04-21 |
2007-01-17 |
AstraZeneca AB |
Pyrazole derivatives useful for the treatment of cancer
|
|
WO2005105788A1
(en)
*
|
2004-04-23 |
2005-11-10 |
Takeda San Diego, Inc. |
Indole derivatives and use thereof as kinase inhibitors
|
|
EP1751136B1
(en)
*
|
2004-05-07 |
2014-07-02 |
Amgen Inc. |
Nitrogenated heterocyclic derivatives as protein kinase modulators and use for the treatment of angiogenesis and cancer
|
|
US7793137B2
(en)
|
2004-10-07 |
2010-09-07 |
Cisco Technology, Inc. |
Redundant power and data in a wired data telecommunincations network
|
|
ES2540987T3
(es)
*
|
2004-05-14 |
2015-07-15 |
Millennium Pharmaceuticals, Inc. |
Métodos para preparar inhibidores de la aurora cinasa
|
|
US20050255485A1
(en)
*
|
2004-05-14 |
2005-11-17 |
Livak Kenneth J |
Detection of gene duplications
|
|
EP1905773B1
(en)
*
|
2004-05-14 |
2012-07-18 |
Millennium Pharmaceuticals, Inc. |
Compounds and methods for inhibiting mitotic progression by inhibition of aurora kinase
|
|
AU2012200416B2
(en)
*
|
2004-05-14 |
2014-07-31 |
Millennium Pharmaceuticals, Inc. |
"Compounds and methods for inhibiting mitotic progression by inhibition of Aurora kinase"
|
|
JP4993604B2
(ja)
*
|
2004-05-14 |
2012-08-08 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
ピロリルピリミジンｅｒｋプロテインキナーゼインヒビターのプロドラッグ
|
|
JP2007538102A
(ja)
*
|
2004-05-20 |
2007-12-27 |
バイエル・フアーマシユーチカルズ・コーポレーシヨン |
糖尿病の処置に有用な５−アニリノ−４−ヘテロアリールピラゾール誘導体
|
|
KR20070034519A
(ko)
*
|
2004-05-27 |
2007-03-28 |
이 아이 듀폰 디 네모아 앤드 캄파니 |
광감성 중합체 보호층용 현상제
|
|
EP1765325A4
(en)
*
|
2004-07-01 |
2009-08-12 |
Synta Pharmaceuticals Corp |
HETEROARYL COMPOUNDS SUBSTITUTED IN 2
|
|
CN101031551A
(zh)
*
|
2004-07-06 |
2007-09-05 |
安吉永生物制药公司 |
针对癌症治疗的肝细胞生长因子/c－met活性的喹唑啉调节剂
|
|
EP1778669A2
(en)
|
2004-08-18 |
2007-05-02 |
Takeda San Diego, Inc. |
Kinase inhibitors
|
|
TW200624431A
(en)
|
2004-09-24 |
2006-07-16 |
Hoffmann La Roche |
Phthalazinone derivatives, their manufacture and use as pharmaceutical agents
|
|
US7285569B2
(en)
|
2004-09-24 |
2007-10-23 |
Hoff Hoffmann-La Roche Inc. |
Tricycles, their manufacture and use as pharmaceutical agents
|
|
CN101031550B
(zh)
*
|
2004-09-30 |
2015-05-27 |
泰博特克药品有限公司 |
抑制hiv的5-碳环-或杂环取代的嘧啶类
|
|
RU2405778C2
(ru)
*
|
2004-09-30 |
2010-12-10 |
Тиботек Фармасьютикалз Лтд. |
5-гетероциклилпиримидины, ингибирующие вич
|
|
ATE542802T1
(de)
*
|
2004-09-30 |
2012-02-15 |
Tibotec Pharm Ltd |
Hiv-inhibierende 5-substituierte pyrimidine
|
|
ATE479687T1
(de)
|
2004-10-15 |
2010-09-15 |
Takeda Pharmaceutical |
Kinaseinhibitoren
|
|
EP1813609B1
(en)
*
|
2004-10-29 |
2013-06-19 |
Msd K.K. |
Novel aminopyridine derivatives having selective aurora-a inhibitory effect
|
|
US7491720B2
(en)
|
2004-10-29 |
2009-02-17 |
Banyu Pharmaceutical Co., Ltd. |
Aminopyridine derivatives having Aurora A selective inhibitory action
|
|
US7767680B2
(en)
|
2004-11-03 |
2010-08-03 |
Vertex Pharmaceuticals Incorporated |
Ion channel modulators and methods of use
|
|
JP2008520713A
(ja)
*
|
2004-11-17 |
2008-06-19 |
ミイカナ セラピューティクス インコーポレイテッド |
キナーゼ阻害剤
|
|
EP1814878B1
(en)
|
2004-11-24 |
2012-01-04 |
Rigel Pharmaceuticals, Inc. |
Spiro-2, 4-pyrimidinediamine compounds and their uses
|
|
US20060128710A1
(en)
*
|
2004-12-09 |
2006-06-15 |
Chih-Hung Lee |
Antagonists to the vanilloid receptor subtype 1 (VR1) and uses thereof
|
|
JP2008525422A
(ja)
*
|
2004-12-23 |
2008-07-17 |
ファイザー・プロダクツ・インク |
抗癌剤として有用な複素芳香族誘導体
|
|
EP1833819A1
(en)
|
2004-12-30 |
2007-09-19 |
Astex Therapeutics Limited |
Pyrazole compounds that modulate the activity of cdk, gsk and aurora kinases
|
|
AU2005322855B2
(en)
|
2004-12-30 |
2012-09-20 |
Exelixis, Inc. |
Pyrimidine derivatives as kinase modulators and method of use
|
|
CA2592900A1
(en)
|
2005-01-03 |
2006-07-13 |
Myriad Genetics Inc. |
Nitrogen containing bicyclic compounds and therapeutical use thereof
|
|
US8258145B2
(en)
|
2005-01-03 |
2012-09-04 |
Myrexis, Inc. |
Method of treating brain cancer
|
|
DE602006010979D1
(de)
|
2005-01-19 |
2010-01-21 |
Rigel Pharmaceuticals Inc |
Prodrugs aus 2,4-pyrimidindiamin-verbindungen und ihre verwendungen
|
|
AR054425A1
(es)
|
2005-01-21 |
2007-06-27 |
Astex Therapeutics Ltd |
Sales de adicion de piperidin 4-il- amida de acido 4-(2,6-dicloro-benzoilamino) 1h-pirazol-3-carboxilico.
|
|
US8404718B2
(en)
|
2005-01-21 |
2013-03-26 |
Astex Therapeutics Limited |
Combinations of pyrazole kinase inhibitors
|
|
DE602006010991D1
(de)
*
|
2005-01-26 |
2010-01-21 |
Schering Corp |
3-(indazol-5-yl)-(1,2,4)triazinderivate und verwandte verbindungen als proteinkinaseinhibitoren zur behandlung von krebs
|
|
DK1846394T3
(da)
|
2005-02-04 |
2012-01-16 |
Astrazeneca Ab |
Pyrazolylaminopyridinderivater, der er egnede som kinaseinhibitorer
|
|
CA2598076A1
(en)
*
|
2005-02-16 |
2006-08-24 |
Astrazeneca Ab |
Chemical compounds
|
|
PT1853588E
(pt)
*
|
2005-02-16 |
2008-08-25 |
Astrazeneca Ab |
Compostos químicos
|
|
CA2600144A1
(en)
*
|
2005-03-15 |
2006-09-28 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
|
JP2008534481A
(ja)
*
|
2005-03-23 |
2008-08-28 |
アストラゼネカ アクチボラグ |
インスリン様増殖因子−１受容体活性の阻害剤としての２−アゼチジニル−４−（１ｈ−ピラゾール−３−イルアミノ）ピリミジン
|
|
US7297700B2
(en)
*
|
2005-03-24 |
2007-11-20 |
Renovis, Inc. |
Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
|
|
SI1869032T1
(sl)
*
|
2005-04-05 |
2008-12-31 |
Astrazeneca Ab |
Pirimidinski derivati za uporabo kot sredstva proti raku
|
|
GB0507347D0
(en)
*
|
2005-04-12 |
2005-05-18 |
Astrazeneca Ab |
Chemical compounds
|
|
US7462639B2
(en)
|
2005-04-14 |
2008-12-09 |
Hoffmann-La Roche Inc. |
Aminopyrazole derivatives
|
|
JP2008540335A
(ja)
*
|
2005-04-27 |
2008-11-20 |
アストラゼネカ・アクチエボラーグ |
ピラゾリル・ピリミジン誘導体の疼痛治療における使用
|
|
AU2006241825A1
(en)
|
2005-04-28 |
2006-11-09 |
Mitsubishi Tanabe Pharma Corporation |
Cyanopyridine derivative and use thereof as medicine
|
|
MX2007013595A
(es)
|
2005-05-04 |
2008-01-24 |
Renovis Inc |
Compuestos heterociclicos fusionados y composiciones y usos de estos.
|
|
US20080207594A1
(en)
|
2005-05-04 |
2008-08-28 |
Davelogen Aktiengesellschaft |
Use of Gsk-3 Inhibitors for Preventing and Treating Pancreatic Autoimmune Disorders
|
|
CN101218229A
(zh)
*
|
2005-05-05 |
2008-07-09 |
阿斯利康(瑞典)有限公司 |
吡唑基-氨基取代的嘧啶及其在癌症治疗中的应用
|
|
EP1899323A2
(en)
*
|
2005-05-16 |
2008-03-19 |
AstraZeneca AB |
Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors
|
|
WO2006133426A2
(en)
|
2005-06-08 |
2006-12-14 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
US8193206B2
(en)
|
2005-06-14 |
2012-06-05 |
Taigen Biotechnology Co., Ltd. |
Pyrimidine compounds
|
|
JP5118029B2
(ja)
|
2005-06-14 |
2013-01-16 |
タイゲン バイオテクノロジー カンパニー，リミテッド |
ピリミジン化合物
|
|
EP1746096A1
(en)
|
2005-07-15 |
2007-01-24 |
4Sc Ag |
2-Arylbenzothiazole analogues and uses thereof in the treatment of cancer
|
|
AU2006279376B2
(en)
*
|
2005-08-18 |
2011-04-14 |
Vertex Pharmaceuticals Incoporated |
Pyrazine kinase inhibitors
|
|
WO2007023382A2
(en)
*
|
2005-08-25 |
2007-03-01 |
Pfizer Inc. |
Pyrimidine amino pyrazole compounds, potent kinase inhibitors
|
|
EP2258358A3
(en)
|
2005-08-26 |
2011-09-07 |
Braincells, Inc. |
Neurogenesis with acetylcholinesterase inhibitor
|
|
EP1928437A2
(en)
|
2005-08-26 |
2008-06-11 |
Braincells, Inc. |
Neurogenesis by muscarinic receptor modulation
|
|
CA2622352C
(en)
*
|
2005-09-30 |
2014-05-27 |
Miikana Therapeutics, Inc. |
Substituted pyrazole compounds
|
|
CN101316587B
(zh)
*
|
2005-09-30 |
2013-04-03 |
迈卡纳治疗股份有限公司 |
取代的吡唑化合物
|
|
US8119655B2
(en)
|
2005-10-07 |
2012-02-21 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
|
EP1940389A2
(en)
|
2005-10-21 |
2008-07-09 |
Braincells, Inc. |
Modulation of neurogenesis by pde inhibition
|
|
WO2007049041A1
(en)
|
2005-10-28 |
2007-05-03 |
Astrazeneca Ab |
4- (3-aminopyrazole) pyrimidine derivatives for use as tyrosine kinase inhibitors in the treatment of cancer
|
|
US20070112017A1
(en)
|
2005-10-31 |
2007-05-17 |
Braincells, Inc. |
Gaba receptor mediated modulation of neurogenesis
|
|
NZ567858A
(en)
*
|
2005-11-01 |
2011-08-26 |
Array Biopharma Inc |
Pyridine compounds useful as Glucokinase activators
|
|
EP1954277B1
(en)
*
|
2005-11-03 |
2017-01-18 |
Vertex Pharmaceuticals Incorporated |
Aminopyrimidines useful as kinase inhibitors
|
|
CA2629781A1
(en)
*
|
2005-11-16 |
2007-05-24 |
Vertex Pharmaceuticals Incorporated |
Aminopyrimidines useful as kinase inhibitors
|
|
US8546404B2
(en)
|
2005-12-13 |
2013-10-01 |
Merck Sharp & Dohme |
Compounds that are ERK inhibitors
|
|
US7572809B2
(en)
|
2005-12-19 |
2009-08-11 |
Hoffmann-La Roche Inc. |
Isoquinoline aminopyrazole derivatives
|
|
EP1968579A1
(en)
|
2005-12-30 |
2008-09-17 |
Astex Therapeutics Limited |
Pharmaceutical compounds
|
|
WO2007081978A2
(en)
*
|
2006-01-11 |
2007-07-19 |
Angion Biomedica Corporation |
Modulators of hepatocyte growth factor / c-met activity
|
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
|
MX2008010635A
(es)
*
|
2006-02-16 |
2008-10-28 |
Schering Corp |
Derivados de pirrolidina como inhibidores de cinasa regulada por señales extracelulares.
|
|
US20100216734A1
(en)
|
2006-03-08 |
2010-08-26 |
Braincells, Inc. |
Modulation of neurogenesis by nootropic agents
|
|
PE20080145A1
(es)
*
|
2006-03-21 |
2008-02-11 |
Janssen Pharmaceutica Nv |
Tetrahidro-pirimidoazepinas como moduladores de trpv1
|
|
WO2007113254A1
(en)
|
2006-03-30 |
2007-10-11 |
Tibotec Pharmaceuticals Ltd. |
Hiv inhibiting 5-amido substituted pyrimidines
|
|
JP5255559B2
(ja)
*
|
2006-03-31 |
2013-08-07 |
アボット・ラボラトリーズ |
インダゾール化合物
|
|
ES2400375T3
(es)
|
2006-04-07 |
2013-04-09 |
Novartis Ag |
Combinación que comprende A) un compuesto de pirimidilaminobenzamida y B)un inhibidor de cinasa THR315LLE
|
|
KR20080109096A
(ko)
|
2006-04-14 |
2008-12-16 |
프라나 바이오테크놀로지 리미티드 |
연령 관련 황반 변성（에이엠디）의 치료 방법
|
|
AU2007244183B2
(en)
*
|
2006-04-27 |
2012-05-10 |
Msd K.K. |
Novel aminopyridine derivative having aurora-a-selective inhibitory activity
|
|
AU2007249399A1
(en)
|
2006-05-09 |
2007-11-22 |
Braincells, Inc. |
Neurogenesis by modulating angiotensin
|
|
WO2007134077A2
(en)
|
2006-05-09 |
2007-11-22 |
Braincells, Inc. |
5 ht receptor mediated neurogenesis
|
|
BRPI0713378A8
(pt)
|
2006-06-27 |
2018-01-02 |
Takeda Pharmaceutical |
composto, pró-droga, modulador da função do receptor gpr40, agente farmacêutico uso do composto, e, método de produção de uma forma opticamente ativa de um composto
|
|
WO2008001101A2
(en)
*
|
2006-06-29 |
2008-01-03 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
|
EP2049119A2
(en)
|
2006-06-29 |
2009-04-22 |
Astex Therapeutics Limited |
Pharmaceutical combinations of 1-cyclopropyl-3-[3-(5-morphoolin-4-ylmethyl-1h-benzoimidazol-2-yl)-1h-1-pyrazol-4-yl]-urea
|
|
WO2008001886A1
(en)
*
|
2006-06-30 |
2008-01-03 |
Kyowa Hakko Kirin Co., Ltd. |
Aurora inhibitor
|
|
JP2009541480A
(ja)
*
|
2006-06-30 |
2009-11-26 |
アストラゼネカ アクチボラグ |
癌の治療において有用なピリミジン誘導体
|
|
EP2043651A2
(en)
|
2006-07-05 |
2009-04-08 |
Exelixis, Inc. |
Methods of using igf1r and abl kinase modulators
|
|
JP2010500300A
(ja)
|
2006-08-08 |
2010-01-07 |
サノフィ−アベンティス |
アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用
|
|
US7718648B2
(en)
*
|
2006-08-09 |
2010-05-18 |
Millennium Pharmaceuticals, Inc. |
Pyridobenzazepine compounds and methods for inhibiting mitotic progression
|
|
US7744164B2
(en)
*
|
2006-08-11 |
2010-06-29 |
Schluimberger Technology Corporation |
Shield of a degradation assembly
|
|
JP2008081492A
(ja)
*
|
2006-08-31 |
2008-04-10 |
Banyu Pharmaceut Co Ltd |
オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
|
|
EP2068872A1
(en)
|
2006-09-08 |
2009-06-17 |
Braincells, Inc. |
Combinations containing a 4-acylaminopyridine derivative
|
|
US20100184806A1
(en)
|
2006-09-19 |
2010-07-22 |
Braincells, Inc. |
Modulation of neurogenesis by ppar agents
|
|
SG158147A1
(en)
|
2006-10-09 |
2010-01-29 |
Takeda Pharmaceutical |
Kinase inhibitors
|
|
EP2223925A1
(en)
*
|
2006-10-09 |
2010-09-01 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
|
JP5528807B2
(ja)
|
2006-10-12 |
2014-06-25 |
アステックス、セラピューティックス、リミテッド |
複合薬剤
|
|
WO2008044041A1
(en)
|
2006-10-12 |
2008-04-17 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
|
WO2008053812A1
(en)
*
|
2006-10-27 |
2008-05-08 |
Mitsubishi Tanabe Pharma Corporation |
Cyanopyridine derivative and medicinal use thereof
|
|
MX2009004807A
(es)
*
|
2006-11-02 |
2009-06-15 |
Vertex Pharma |
Aminopiridinas y aminopirimidinas utiles como inhibidores de proteina cinasa.
|
|
CL2007003244A1
(es)
|
2006-11-16 |
2008-04-04 |
Millennium Pharm Inc |
Compuestos derivados de pirimido[5,4-d][2]benzazepina; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento del cancer.
|
|
NZ577768A
(en)
*
|
2006-12-19 |
2012-01-12 |
Vertex Pharma |
Aminopyrimidines useful as inhibitors of protein kinases
|
|
JP5185283B2
(ja)
*
|
2006-12-29 |
2013-04-17 |
テイボテク・フアーマシユーチカルズ |
Ｈｉｖ阻害６−置換ピリミジン
|
|
EP2114902B1
(en)
*
|
2006-12-29 |
2014-09-17 |
Janssen R&D Ireland |
Hiv inhibiting 5,6-substituted pyrimidines
|
|
WO2008098058A1
(en)
|
2007-02-06 |
2008-08-14 |
Novartis Ag |
Pi 3-kinase inhibitors and methods of their use
|
|
KR20090115866A
(ko)
|
2007-03-05 |
2009-11-09 |
교와 핫꼬 기린 가부시키가이샤 |
의약 조성물
|
|
ATE526328T1
(de)
*
|
2007-03-09 |
2011-10-15 |
Vertex Pharma |
Als inhibitoren von proteinkinasen geeignete aminopyrimidine
|
|
MX2009009592A
(es)
|
2007-03-09 |
2009-11-10 |
Vertex Pharma |
Aminopiridinas utiles como inhibidores de proteinas cinasas.
|
|
MX2009009590A
(es)
*
|
2007-03-09 |
2009-11-10 |
Vertex Pharma |
Aminopirimidinas utiles como inhibidores de proteinas cinasas.
|
|
CA2682195A1
(en)
*
|
2007-03-20 |
2008-09-25 |
Vertex Pharmaceuticals Incorporated |
Aminopyrimidines useful as kinase inhibitors
|
|
WO2008117050A1
(en)
*
|
2007-03-27 |
2008-10-02 |
Astrazeneca Ab |
Pyrazolyl-amino-substituted pyrazines and their use for the treatment of cancer
|
|
AU2008240313A1
(en)
*
|
2007-04-13 |
2008-10-23 |
Aj Park |
Aminopyrimidines useful as kinase inhibitors
|
|
BRPI0810411B8
(pt)
|
2007-04-18 |
2021-05-25 |
Pfizer Prod Inc |
derivados de sulfonil amida para o tratamento de crescimento celular anormal, seu sos, bem como composição farmacêutica
|
|
WO2008129255A1
(en)
*
|
2007-04-18 |
2008-10-30 |
Astrazeneca Ab |
5-aminopyrazol-3-yl-3h-imidazo [4,5-b] pyridine derivatives and their use for the treatment of cancer
|
|
AU2008247592A1
(en)
|
2007-05-02 |
2008-11-13 |
Vertex Pharmaceuticals Incorporated |
Thiazoles and pyrazoles useful as kinase inhibitors
|
|
JP5389786B2
(ja)
|
2007-05-02 |
2014-01-15 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
キナーゼ阻害として有用なアミノピリミジン
|
|
CN101679387A
(zh)
*
|
2007-05-02 |
2010-03-24 |
沃泰克斯药物股份有限公司 |
可用作激酶抑制剂的氨基嘧啶类化合物
|
|
US20100137398A1
(en)
*
|
2007-05-04 |
2010-06-03 |
Novartis Ag |
Use of hdac inhibitors for the treatment of gastrointestinal cancers
|
|
UA99459C2
(en)
*
|
2007-05-04 |
2012-08-27 |
Астразенека Аб |
9-(pyrazol-3-yl)- 9h-purine-2-amine and 3-(pyraz0l-3-yl)-3h-imidazo[4,5-b]pyridin-5-amine derivatives and their use for the treatment of cancer
|
|
MX2009012719A
(es)
*
|
2007-05-24 |
2010-02-04 |
Vertex Pharma |
Tiazoles y pirazoles utiles como inhibidores de cinasa.
|
|
KR101294731B1
(ko)
*
|
2007-06-04 |
2013-08-16 |
삼성디스플레이 주식회사 |
어레이 기판, 이를 갖는 표시패널 및 이의 제조방법
|
|
AU2008262291A1
(en)
*
|
2007-06-11 |
2008-12-18 |
Miikana Therapeutics, Inc. |
Substituted pyrazole compounds
|
|
EP2178563A2
(en)
*
|
2007-07-06 |
2010-04-28 |
OSI Pharmaceuticals, Inc. |
Combination anti-cancer therapy comprising an inhibitor of both mtorc1 and mtorc2
|
|
WO2009007753A2
(en)
*
|
2007-07-11 |
2009-01-15 |
Astrazeneca Ab |
4- (3-aminopyrazole) -pyrimidine derivativee and their use as tyrosine kinase inhibitors for the treatment of cancer
|
|
KR20100038108A
(ko)
*
|
2007-07-25 |
2010-04-12 |
브리스톨-마이어스 스큅 컴퍼니 |
트리아진 키나제 억제제
|
|
WO2009013545A2
(en)
*
|
2007-07-26 |
2009-01-29 |
Astrazeneca Ab |
Chemical compounds
|
|
TW200906818A
(en)
*
|
2007-07-31 |
2009-02-16 |
Astrazeneca Ab |
Chemical compounds
|
|
CN101790532B
(zh)
*
|
2007-07-31 |
2013-11-20 |
沃泰克斯药物股份有限公司 |
5-氟-1H-吡唑并[3，4-b]吡啶-3-胺及其衍生物的制备方法
|
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
WO2009027736A2
(en)
*
|
2007-08-27 |
2009-03-05 |
Astrazeneca Ab |
2,4 diaminopyrimid'lnes for the treatment of myeloproliferative disorders and cancer
|
|
AU2008305294B2
(en)
|
2007-09-21 |
2012-11-29 |
Array Biopharma Inc. |
Pyridin-2 -yl-amino-1, 2, 4 -thiadiazole derivatives as glucokinase activators for the treatment of diabetes mellitus
|
|
JP5372943B2
(ja)
|
2007-10-11 |
2013-12-18 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー |
新規ｓＥＨ阻害剤およびそれらの使用
|
|
WO2009078999A1
(en)
|
2007-12-17 |
2009-06-25 |
Janssen Pharmaceutica N.V. |
Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of trpv1
|
|
US20090270418A1
(en)
*
|
2008-01-09 |
2009-10-29 |
Marianne Sloss |
Pyrazole pyrazine amine compounds as kinase inhibitors, compositions thereof and methods of treatment therewith
|
|
EP2242745A1
(de)
*
|
2008-02-07 |
2010-10-27 |
Sanofi-Aventis |
Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2009105500A1
(en)
|
2008-02-21 |
2009-08-27 |
Schering Corporation |
Compounds that are erk inhibitors
|
|
AU2009216062B2
(en)
*
|
2008-02-22 |
2013-02-07 |
Msd K.K. |
Novel aminopyridine derivatives having Aurora A selective inhibitory action
|
|
AU2008355098B2
(en)
|
2008-04-21 |
2012-11-15 |
Gpcr Therapeutics, Inc |
Heterocyclic compounds
|
|
WO2010011411A1
(en)
|
2008-05-27 |
2010-01-28 |
The Trustees Of Columbia University In The City Of New York |
Systems, methods, and media for detecting network anomalies
|
|
KR20110017445A
(ko)
*
|
2008-06-11 |
2011-02-21 |
아스트라제네카 아베 |
암 및 골수증식성 장애의 치료에 유용한 트리시클릭 2,4-디아미노-ｌ,3,5-트리아진 유도체
|
|
WO2010003624A2
(en)
|
2008-07-09 |
2010-01-14 |
Sanofi-Aventis |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
|
AR073354A1
(es)
*
|
2008-07-31 |
2010-11-03 |
Genentech Inc |
Compuestos de pirimidina, composiciones farmaceuticas y su uso en el tratamiento del cancer.
|
|
WO2010027921A1
(en)
*
|
2008-09-03 |
2010-03-11 |
Vertex Pharmaceuticals Incorporated |
Co-crystals and pharmaceutical formulations comprising the same
|
|
JP2012501654A
(ja)
*
|
2008-09-05 |
2012-01-26 |
アビラ セラピューティクス， インコーポレイテッド |
不可逆的インヒビターの設計のためのアルゴリズム
|
|
CN102264728B
(zh)
*
|
2008-09-15 |
2015-02-04 |
加利福尼亚大学董事会 |
用于调节ire1、src和abl活性的方法和组合物
|
|
CN102227422A
(zh)
*
|
2008-09-30 |
2011-10-26 |
阿斯利康(瑞典)有限公司 |
杂环jak激酶抑制剂
|
|
US8759362B2
(en)
*
|
2008-10-24 |
2014-06-24 |
Purdue Pharma L.P. |
Bicycloheteroaryl compounds and their use as TRPV1 ligands
|
|
WO2010056758A1
(en)
*
|
2008-11-12 |
2010-05-20 |
Yangbo Feng |
Quinazoline derivatives as kinase inhibitors
|
|
WO2010056847A2
(en)
|
2008-11-13 |
2010-05-20 |
Taigen Biotechnology Co., Ltd. |
Lyophilization formulation
|
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
|
PA8851101A1
(es)
|
2008-12-16 |
2010-07-27 |
Lilly Co Eli |
Compuesto amino pirazol
|
|
US8524707B2
(en)
*
|
2008-12-19 |
2013-09-03 |
Nerviano Medical Sciences S.R.L. |
Bicyclic pyrazoles as protein kinase inhibitors
|
|
RU2535032C2
(ru)
|
2008-12-22 |
2014-12-10 |
Милленниум Фармасьютикалз, Инк. |
Сочетание ингибиторов аврора киназы и анти-cd 20 антител
|
|
WO2010072155A1
(zh)
*
|
2008-12-26 |
2010-07-01 |
复旦大学 |
一种嘧啶类衍生物及其制备方法和用途
|
|
WO2010099217A1
(en)
|
2009-02-25 |
2010-09-02 |
Braincells, Inc. |
Modulation of neurogenesis using d-cycloserine combinations
|
|
AR075633A1
(es)
*
|
2009-02-27 |
2011-04-20 |
Ambit Biosciences Corp |
Compuestos moduladores de jak quinasa y sus metodos de uso
|
|
CA2660962A1
(en)
|
2009-03-31 |
2010-09-30 |
Astellas Pharma Inc. |
Novel pharmaceutical composition for treatment of schizophrenia
|
|
US8399663B2
(en)
|
2009-04-03 |
2013-03-19 |
Astellas Pharma Inc. |
Salt of 1,3,5-triazine-2,4,6-triamine derivative
|
|
JO3635B1
(ar)
|
2009-05-18 |
2020-08-27 |
Millennium Pharm Inc |
مركبات صيدلانية صلبة وطرق لانتاجها
|
|
AU2010259023A1
(en)
*
|
2009-06-08 |
2012-01-12 |
Nantbioscience, Inc. |
Triazine derivatives and their therapeutical applications
|
|
KR101460095B1
(ko)
*
|
2009-06-08 |
2014-11-10 |
캘리포니아 캐피탈 에쿼티, 엘엘씨 |
트리아진 유도체와 이들의 치료적 용도
|
|
WO2010144394A1
(en)
*
|
2009-06-09 |
2010-12-16 |
Abraxis Bioscience, Llc |
Benzyl substituted triazine derivatives and their therapeutical applications
|
|
KR101457027B1
(ko)
|
2009-06-09 |
2014-10-31 |
캘리포니아 캐피탈 에쿼티, 엘엘씨 |
트리아진 유도체와 이들의 치료적 용도
|
|
BRPI1011320A2
(pt)
*
|
2009-06-09 |
2016-06-21 |
California Capital Equity Llc |
derivados de estiril-triazina e suas aplicações terapêuticas
|
|
AU2010258825B2
(en)
*
|
2009-06-09 |
2014-08-21 |
Nantbio, Inc. |
Ureidophenyl substituted triazine derivatives and their therapeutical applications
|
|
EP2443106A1
(en)
*
|
2009-06-18 |
2012-04-25 |
Cellzome Limited |
Heterocyclylaminopyrimidines as kinase inhibitors
|
|
US8637525B2
(en)
|
2009-07-31 |
2014-01-28 |
Bristol-Myers Squibb Company |
Compounds for the reduction of beta-amyloid production
|
|
TWI468402B
(zh)
*
|
2009-07-31 |
2015-01-11 |
必治妥美雅史谷比公司 |
降低β－類澱粉生成之化合物
|
|
MX2012001729A
(es)
|
2009-08-26 |
2012-06-13 |
Sanofi Sa |
Nuevos hidratos cristalinos de fluoroglicosido heteroaromatico, productos farmaceuticos que comprenden estos compuestos, y su empleo.
|
|
NZ620174A
(en)
*
|
2009-09-16 |
2016-08-26 |
Celgene Avilomics Res Inc |
Protein kinase conjugates and inhibitors
|
|
KR101923049B1
(ko)
*
|
2009-11-13 |
2018-11-28 |
인튜어티브 서지컬 오퍼레이션즈 인코포레이티드 |
여분의 닫힘 메커니즘을 구비한 단부 작동기
|
|
US9180127B2
(en)
|
2009-12-29 |
2015-11-10 |
Dana-Farber Cancer Institute, Inc. |
Type II Raf kinase inhibitors
|
|
EP2519664A4
(en)
|
2009-12-30 |
2014-03-12 |
Avila Therapeutics Inc |
LIGAND-RELATED COVALENTS MODIFYING A PROTEIN
|
|
SA111320200B1
(ar)
*
|
2010-02-17 |
2014-02-16 |
ديبيوفارم اس ايه |
مركبات ثنائية الحلقة واستخداماتها كمثبطات c-src/jak مزدوجة
|
|
CA2788774A1
(en)
|
2010-02-19 |
2011-08-25 |
Millennium Pharmaceuticals, Inc. |
Crystalline forms of sodium 4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}-2-methoxybenzoate
|
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US20130059830A1
(en)
*
|
2010-05-20 |
2013-03-07 |
Fa-Xiang Ding |
Novel prolylcarboxypeptidase inhibitors
|
|
US8927547B2
(en)
|
2010-05-21 |
2015-01-06 |
Noviga Research Ab |
Pyrimidine derivatives
|
|
PT2576541T
(pt)
|
2010-06-04 |
2016-07-08 |
Hoffmann La Roche |
Derivados de aminopirimidina como moduladores de lrrk2
|
|
WO2011157827A1
(de)
|
2010-06-18 |
2011-12-22 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
|
WO2012013728A1
(en)
|
2010-07-29 |
2012-02-02 |
Oryzon Genomics S.A. |
Arylcyclopropylamine based demethylase inhibitors of lsd1 and their medical use
|
|
WO2012030948A1
(en)
*
|
2010-09-01 |
2012-03-08 |
Ambit Biosciences Corporation |
Quinazoline compounds and methods of use thereof
|
|
WO2012030918A1
(en)
*
|
2010-09-01 |
2012-03-08 |
Ambit Biosciences Corporation |
Adenosine a3 receptor modulating compounds and methods of use thereof
|
|
EP2611794A1
(en)
*
|
2010-09-01 |
2013-07-10 |
Ambit Biosciences Corporation |
4-azolylaminoquinazoline derivatives and methods of use thereof
|
|
ES2579942T3
(es)
|
2010-09-01 |
2016-08-17 |
Ambit Biosciences Corporation |
Pirazolilaminoquinazolina ópticamente activa y composiciones farmacéuticas y métodos de uso de la misma
|
|
CN103270030B
(zh)
*
|
2010-09-01 |
2016-01-20 |
埃姆比特生物科学公司 |
吡唑基氨基喹唑啉的氢溴酸盐
|
|
US20130296363A1
(en)
*
|
2010-09-01 |
2013-11-07 |
Ambit Biosciences Corporation |
Quinoline and isoquinoline derivatives for use as jak modulators
|
|
EP2611793A1
(en)
*
|
2010-09-01 |
2013-07-10 |
Ambit Biosciences Corporation |
2-cycloquinazoline derivatives and methods of use thereof
|
|
WO2012059932A1
(en)
|
2010-11-01 |
2012-05-10 |
Aurigene Discovery Technologies Limited |
2, 4 -diaminopyrimidine derivatives as protein kinase inhibitors
|
|
HRP20172006T1
(hr)
|
2010-11-10 |
2018-02-09 |
Genentech, Inc. |
Derivati pirazol-aminopiridina kao lrrk2-modulatori
|
|
EP2683702B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US8828995B2
(en)
|
2011-03-08 |
2014-09-09 |
Sanofi |
Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
|
EP2683701B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8871758B2
(en)
|
2011-03-08 |
2014-10-28 |
Sanofi |
Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
|
WO2012120052A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683698B1
(de)
|
2011-03-08 |
2017-10-04 |
Sanofi |
Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683699B1
(de)
|
2011-03-08 |
2015-06-24 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8895547B2
(en)
|
2011-03-08 |
2014-11-25 |
Sanofi |
Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
|
|
EP2683705B1
(de)
|
2011-03-08 |
2015-04-22 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
DK2688883T3
(en)
|
2011-03-24 |
2016-09-05 |
Noviga Res Ab |
pyrimidine
|
|
MX2014002208A
(es)
*
|
2011-08-25 |
2014-05-28 |
Hoffmann La Roche |
Inhibidores de serina/treonina quinasa.
|
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
KR20140059246A
(ko)
|
2011-09-22 |
2014-05-15 |
화이자 인코포레이티드 |
피롤로피리미딘 및 퓨린 유도체
|
|
KR20140069235A
(ko)
|
2011-09-27 |
2014-06-09 |
노파르티스 아게 |
돌연변이체 idh의 억제제로서의 3-피리미딘-4-일-옥사졸리딘-2-온
|
|
EP2760862B1
(en)
|
2011-09-27 |
2015-10-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
CA2856291C
(en)
|
2011-11-17 |
2020-08-11 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of c-jun-n-terminal kinase (jnk)
|
|
BR112014015549A8
(pt)
|
2011-12-22 |
2017-07-04 |
Hoffmann La Roche |
composto, método de inibição da atividade pak1, método para o tratamento, processo, composição, utilização de um composto e invenção
|
|
ES2655177T3
(es)
*
|
2012-02-17 |
2018-02-19 |
Abbvie Inc. |
Diaminopirimidinas útiles como inhibidores del virus respiratorio sincitial (VRS) humano
|
|
UY34632A
(es)
|
2012-02-24 |
2013-05-31 |
Novartis Ag |
Compuestos de oxazolidin- 2- ona y usos de los mismos
|
|
TWI485146B
(zh)
*
|
2012-02-29 |
2015-05-21 |
Taiho Pharmaceutical Co Ltd |
Novel piperidine compounds or salts thereof
|
|
KR20140138293A
(ko)
|
2012-03-16 |
2014-12-03 |
액시킨 파마수티컬스 인코포레이티드 |
3,5-다이아미노피라졸 키나아제 억제제
|
|
US20130303519A1
(en)
|
2012-03-20 |
2013-11-14 |
Millennium Pharmaceuticals, Inc. |
Methods of treating cancer using aurora kinase inhibitors
|
|
JP6378171B2
(ja)
|
2012-04-24 |
2018-08-22 |
バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ |
Ｄｎａ−ｐｋ阻害剤
|
|
EP2855451B1
(en)
*
|
2012-05-24 |
2017-10-04 |
Cellzome Limited |
Heterocyclyl pyrimidine analogues as tyk2 inhibitors
|
|
JP6280546B2
(ja)
|
2012-06-26 |
2018-02-14 |
デル マー ファーマシューティカルズ |
ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はａｈｉ１の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法
|
|
SG11201500005SA
(en)
*
|
2012-07-10 |
2015-01-29 |
Ares Trading Sa |
Pyrimidine pyrazolyl derivatives
|
|
MY183976A
(en)
*
|
2012-09-19 |
2021-03-17 |
Taiho Pharmaceutical Co Ltd |
Pharmaceutical composition for oral administration with improved dissolution and/or absorption
|
|
US9296733B2
(en)
|
2012-11-12 |
2016-03-29 |
Novartis Ag |
Oxazolidin-2-one-pyrimidine derivative and use thereof for the treatment of conditions, diseases and disorders dependent upon PI3 kinases
|
|
CN103059002B
(zh)
*
|
2012-12-31 |
2015-04-22 |
中山大学 |
具有Aurora激酶抑制活性的嘧啶衍生物及其制备方法以及应用
|
|
CN103191120B
(zh)
*
|
2012-12-31 |
2015-11-25 |
刘强 |
一种嘧啶衍生物在制备预防和/或治疗和/或辅助治疗肿瘤的药物中的用途
|
|
CN103202843B
(zh)
*
|
2012-12-31 |
2015-04-29 |
刘强 |
一种嘧啶衍生物在制备预防和/或治疗和/或辅助治疗癌症的药物中的用途
|
|
CN103910716A
(zh)
*
|
2013-01-07 |
2014-07-09 |
华东理工大学 |
2,4-二取代-环烷基[d]嘧啶类化合物及其用途
|
|
SI3527563T1
(sl)
|
2013-03-12 |
2022-01-31 |
Vertex Pharmaceuticals Incorporated |
Inhibitorji DNA-PK
|
|
EP2970240B1
(en)
|
2013-03-14 |
2018-01-10 |
Novartis AG |
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh
|
|
EP3842424B1
(en)
|
2013-03-15 |
2024-12-11 |
The Trustees of Columbia University in the City of New York |
Map kinase modulators and uses thereof in the tretament of tauopathies
|
|
WO2014153509A1
(en)
|
2013-03-22 |
2014-09-25 |
Millennium Pharmaceuticals, Inc. |
Combination of catalytic mtorc 1/2 inhibitors and selective inhibitors of aurora a kinase
|
|
WO2015003355A2
(en)
*
|
2013-07-11 |
2015-01-15 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
CN105764501A
(zh)
|
2013-07-26 |
2016-07-13 |
现代化制药公司 |
改善比生群治疗效益的组合物
|
|
WO2015028848A1
(en)
*
|
2013-09-02 |
2015-03-05 |
Piramal Enterprises Limited |
Bicyclic heterocyclic compounds as multi-kinase inhibitors
|
|
NZ631142A
(en)
|
2013-09-18 |
2016-03-31 |
Axikin Pharmaceuticals Inc |
Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
|
|
RU2675270C2
(ru)
|
2013-10-17 |
2018-12-18 |
Вертекс Фармасьютикалз Инкорпорейтед |
Сокристаллы и содержащие их фармацевтические композиции
|
|
EP3057955B1
(en)
|
2013-10-18 |
2018-04-11 |
Syros Pharmaceuticals, Inc. |
Heteroaromatic compounds useful for the treatment of prolferative diseases
|
|
US10047070B2
(en)
|
2013-10-18 |
2018-08-14 |
Dana-Farber Cancer Institute, Inc. |
Polycyclic inhibitors of cyclin-dependent kinase 7 (CDK7)
|
|
HRP20201384T1
(hr)
|
2014-01-01 |
2020-11-27 |
Medivation Technologies Llc |
Spojevi i postupci njihove upotrebe
|
|
US10258585B2
(en)
|
2014-03-13 |
2019-04-16 |
Neuroderm, Ltd. |
DOPA decarboxylase inhibitor compositions
|
|
ES2967693T3
(es)
|
2014-03-13 |
2024-05-03 |
Neuroderm Ltd |
Composiciones del inhibidor de la dopa descarboxilasa
|
|
MX2016012574A
(es)
*
|
2014-03-28 |
2017-09-26 |
Calitor Sciences Llc |
Compuestos heteroarilo sustituidos y metodos de uso.
|
|
NZ725860A
(en)
|
2014-04-04 |
2019-08-30 |
Iomet Pharma Ltd |
Indole derivatives for use in medicine
|
|
US20170165230A1
(en)
|
2014-04-09 |
2017-06-15 |
Christopher Rudd |
Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity
|
|
CN105367555B
(zh)
*
|
2014-08-07 |
2019-06-25 |
广东东阳光药业有限公司 |
取代的杂芳基化合物及其组合物和用途
|
|
EP3929190B1
(en)
|
2014-10-13 |
2024-12-25 |
Yuhan Corporation |
Compounds and compositions for modulating egfr mutant kinase activities
|
|
US9546163B2
(en)
|
2014-12-23 |
2017-01-17 |
Axikin Pharmaceuticals, Inc. |
3,5-diaminopyrazole kinase inhibitors
|
|
AU2015371251B2
(en)
|
2014-12-23 |
2020-06-11 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (CDK7)
|
|
US10227343B2
(en)
*
|
2015-01-30 |
2019-03-12 |
Vanderbilt University |
Isoquiniline and napthalene-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
|
|
HK1246645A1
(zh)
|
2015-03-27 |
2018-09-14 |
达纳-法伯癌症研究所股份有限公司 |
细胞周期蛋白依赖性激酶的抑制剂
|
|
AU2016247858B2
(en)
|
2015-04-17 |
2020-10-15 |
Ludwig Institute For Cancer Research Ltd. |
PLK4 inhibitors
|
|
JP6692836B2
(ja)
|
2015-05-28 |
2020-05-13 |
セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー |
Ｊａｋキナーゼ阻害剤としてのナフチリジン化合物
|
|
JP2018135268A
(ja)
*
|
2015-06-05 |
2018-08-30 |
大日本住友製薬株式会社 |
新規ヘテロアリールアミノ−３−ピラゾール誘導体およびその薬理学上許容される塩
|
|
JP2018524292A
(ja)
|
2015-07-21 |
2018-08-30 |
ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． |
オーロラキナーゼインヒビターと化学療法剤の投与
|
|
EP3347018B1
(en)
|
2015-09-09 |
2021-09-01 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinases
|
|
WO2017044434A1
(en)
|
2015-09-11 |
2017-03-16 |
Sunshine Lake Pharma Co., Ltd. |
Substituted heteroaryl compounds and methods of use
|
|
EA201800367A1
(ru)
*
|
2015-12-10 |
2019-02-28 |
ПиТиСи ТЕРАПЬЮТИКС, ИНК. |
Способы лечения болезни хантингтона
|
|
CN105399695B
(zh)
*
|
2015-12-11 |
2019-04-19 |
浙江大学 |
三嗪类化合物及其制备方法和用途
|
|
CN105384702B
(zh)
*
|
2015-12-11 |
2018-04-10 |
浙江大学 |
三取代均三嗪类化合物及其制备方法
|
|
CN105503754B
(zh)
*
|
2015-12-11 |
2017-11-17 |
浙江大学 |
2‑氨基‑4‑苄基‑6‑吗啉‑1,3,5‑三嗪及其制备和应用
|
|
WO2017102091A1
(en)
|
2015-12-18 |
2017-06-22 |
Bayer Pharma Aktiengesellschaft |
Heteroarylbenzimidazole compounds
|
|
MA43821A
(fr)
|
2016-03-14 |
2018-11-28 |
Afferent Pharmaceuticals Inc |
Pyrimidines et variantes de celles-ci, et leurs utilisations
|
|
MA44489A
(fr)
|
2016-03-25 |
2019-01-30 |
Afferent Pharmaceuticals Inc |
Pyrimidines et variants de celles-ci, et leurs utilisations
|
|
MX377180B
(es)
|
2016-04-28 |
2025-03-07 |
Theravance Biopharma R&D Ip Llc |
Compuestos de pirimidina como inhibidores de la quinasa jak.
|
|
WO2017207534A1
(en)
|
2016-06-03 |
2017-12-07 |
Bayer Pharma Aktiengesellschaft |
Substituted heteroarylbenzimidazole compounds
|
|
RU2758669C2
(ru)
|
2016-09-27 |
2021-11-01 |
Вертекс Фармасьютикалз Инкорпорейтед |
Способ лечения рака с применением сочетания днк-поражающих агентов и ингибиторов днк-пк
|
|
US10858319B2
(en)
|
2016-10-03 |
2020-12-08 |
Iomet Pharma Ltd. |
Indole derivatives for use in medicine
|
|
US10968227B2
(en)
*
|
2016-11-08 |
2021-04-06 |
Vanderbilt University |
Isoquinoline ether compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
|
|
CN108239071B
(zh)
*
|
2016-12-27 |
2020-12-04 |
沈阳药科大学 |
酰胺及硫代酰胺类衍生物及其制备方法和应用
|
|
FR3064275B1
(fr)
|
2017-03-21 |
2019-06-07 |
Arkema France |
Procede de chauffage et/ou climatisation d'un vehicule
|
|
EA201992764A1
(ru)
|
2017-05-30 |
2020-04-29 |
Басф Се |
Пиридиновые и пиразиновые соединения
|
|
EP3634953B1
(en)
|
2017-06-05 |
2024-01-03 |
PTC Therapeutics, Inc. |
Compounds for treating huntington's disease
|
|
MX2019015580A
(es)
|
2017-06-28 |
2020-07-28 |
Ptc Therapeutics Inc |
Metodos para tratar la enfermedad de huntington.
|
|
CN111182898B
(zh)
|
2017-06-28 |
2024-04-16 |
Ptc医疗公司 |
用于治疗亨廷顿氏病的方法
|
|
WO2019000682A1
(zh)
*
|
2017-06-30 |
2019-01-03 |
北京泰德制药股份有限公司 |
Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
|
|
CN110582489B
(zh)
|
2017-06-30 |
2023-10-27 |
北京泰德制药股份有限公司 |
Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
|
|
US10323023B2
(en)
|
2017-06-30 |
2019-06-18 |
Beijing Tide Pharmaceutical Co., Ltd. |
Rho-associated protein kinase inhibitor, pharmaceutical composition comprising the same, as well as preparation method and use thereof
|
|
EP3675860B1
(en)
*
|
2017-08-28 |
2023-03-08 |
Zhihong, Chen |
Substituted pyrimidines, pharmaceutical compositions and therapeutic methods thereof
|
|
WO2019046316A1
(en)
*
|
2017-08-28 |
2019-03-07 |
Acurastem Inc. |
PIKFYVE KINASE INHIBITORS
|
|
HRP20221221T1
(hr)
|
2017-10-27 |
2022-12-09 |
Theravance Biopharma R&D Ip, Llc |
Pirimidinski spoj kao inhibitor jak kinaze
|
|
KR20200090198A
(ko)
*
|
2017-11-23 |
2020-07-28 |
바이오메드 엑스 게엠베하 |
트로포미오신 수용체 키나제 A(TrkA) 저해제로서의 피리미딘 유도체
|
|
EP3720560A4
(en)
*
|
2017-12-06 |
2022-01-05 |
Ludwig Institute for Cancer Research Ltd |
METHOD OF TREATMENT OF CANCER WITH PLK4 INHIBITORS
|
|
KR20200143376A
(ko)
|
2018-03-13 |
2020-12-23 |
샤이어 휴먼 지네틱 테라피즈 인크. |
혈장 칼리크레인 억제제로서의 치환된 이미다조피리딘 및 이의 용도
|
|
EA202092001A1
(ru)
|
2018-03-27 |
2021-01-29 |
ПиТиСи ТЕРАПЬЮТИКС, ИНК. |
Соединения для лечения болезни гентингтона
|
|
US12187701B2
(en)
|
2018-06-25 |
2025-01-07 |
Dana-Farber Cancer Institute, Inc. |
Taire family kinase inhibitors and uses thereof
|
|
HRP20240935T1
(hr)
|
2018-06-27 |
2024-11-22 |
Ptc Therapeutics, Inc. |
Heterociklični i heteroaril spojevi za liječenje huntingtonove bolesti
|
|
EP3814360B8
(en)
|
2018-06-27 |
2024-11-06 |
PTC Therapeutics, Inc. |
Heteroaryl compounds for treating huntington's disease
|
|
WO2020005877A1
(en)
|
2018-06-27 |
2020-01-02 |
Ptc Therapeutics, Inc. |
Heteroaryl compounds for treating huntington's disease
|
|
KR102919209B1
(ko)
|
2018-08-10 |
2026-01-28 |
다이아핀 테라퓨틱스, 엘엘씨 |
트리-펩타이드 그리고 대사, 심장혈관 및 염증성 장애의 치료
|
|
JP2022510980A
(ja)
*
|
2018-11-30 |
2022-01-28 |
江▲蘇▼豪森▲薬▼▲業▼集▲団▼有限公司 |
ヘテロ芳香族誘導体調節因子、その製造方法及び使用
|
|
JP7660063B2
(ja)
|
2018-12-28 |
2025-04-10 |
ダナ－ファーバー キャンサー インスティテュート， インコーポレイテッド |
サイクリン依存性キナーゼ７のインヒビターおよびそれらの使用
|
|
TW202106681A
(zh)
|
2019-04-24 |
2021-02-16 |
美商施萬生物製藥研發Ｉｐ有限責任公司 |
用於治療皮膚疾病之嘧啶jak抑制劑
|
|
EP3958969B1
(en)
|
2019-04-24 |
2024-01-10 |
Theravance Biopharma R&D IP, LLC |
Ester and carbonate pyrimidine compounds as jak kinase inhibitors
|
|
JP7649257B2
(ja)
|
2019-05-13 |
2025-03-19 |
ピーティーシー セラピューティクス， インコーポレイテッド |
ハンチントン病を処置するための化合物
|
|
US12428395B2
(en)
|
2019-08-01 |
2025-09-30 |
Sperogenix Therapeutics Limited |
Heterocyclic compounds as kinase inhibitor and uses thereof
|
|
CN114667289B
(zh)
|
2019-09-18 |
2025-08-26 |
武田药品工业有限公司 |
杂芳基血浆激肽释放酶抑制剂
|
|
EP4031547B1
(en)
|
2019-09-18 |
2024-07-17 |
Takeda Pharmaceutical Company Limited |
Plasma kallikrein inhibitors and uses thereof
|
|
CN110483493A
(zh)
*
|
2019-09-19 |
2019-11-22 |
广东工业大学 |
一种二唑类衍生物及其制备方法和应用
|
|
KR20220140515A
(ko)
|
2020-01-13 |
2022-10-18 |
버지 애널리틱스, 인크. |
치환된 피라졸로-피리미딘 및 그의 용도
|
|
US11213502B1
(en)
|
2020-11-17 |
2022-01-04 |
Neuroderm, Ltd. |
Method for treatment of parkinson's disease
|
|
US11844754B2
(en)
|
2020-11-17 |
2023-12-19 |
Neuroderm, Ltd. |
Methods for treatment of Parkinson's disease
|
|
US11331293B1
(en)
|
2020-11-17 |
2022-05-17 |
Neuroderm, Ltd. |
Method for treatment of Parkinson's disease
|
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Ａｌｋ﹘５抑制劑和彼之用途
|
|
EP4308564A1
(en)
*
|
2021-03-17 |
2024-01-24 |
Takeda Pharmaceutical Company Limited |
Polycyclic inhibitors of plasma kallikrein
|
|
KR20230160350A
(ko)
*
|
2021-03-24 |
2023-11-23 |
아토스 테라퓨틱스, 인크. |
키나제-관련 질환의 치료를 위한 소분자
|
|
CN117355304A
(zh)
*
|
2021-03-26 |
2024-01-05 |
住友制药肿瘤公司 |
Alk-5抑制剂及其用途
|
|
CA3213359A1
(en)
*
|
2021-03-26 |
2022-09-29 |
Bettina FRANZ |
Alk-5 inhibitors and uses thereof
|
|
MX2023013225A
(es)
|
2021-05-11 |
2024-01-15 |
Oric Pharmaceuticals Inc |
Inhibidores de la cinasa 4 similar a polo.
|
|
US11932648B2
(en)
|
2021-06-28 |
2024-03-19 |
Blueprint Medicines Corporation |
CDK2 inhibitors
|
|
KR102692529B1
(ko)
*
|
2021-07-01 |
2024-08-08 |
한국원자력의학원 |
Mastl-pp2a를 표적화하는 암의 예방 또는 치료용 약학적 조성물
|
|
CN116354938B
(zh)
*
|
2021-12-28 |
2024-02-20 |
沈阳药科大学 |
一类喹唑啉衍生物与其类似物的制备方法及应用
|
|
CN114276302B
(zh)
*
|
2022-01-11 |
2023-07-25 |
山东百启生物医药有限公司 |
一种制备2,4-二氨基喹唑啉衍生物的方法
|
|
CN116813595B
(zh)
*
|
2022-03-28 |
2025-07-18 |
上海医药工业研究院有限公司 |
喹唑啉类衍生物、其制备方法、药物组合物及应用
|
|
WO2024003773A1
(en)
|
2022-07-01 |
2024-01-04 |
Pfizer Inc. |
2,7-naphthyridine compounds as mastl inhibitors
|
|
CN117736198A
(zh)
*
|
2022-09-21 |
2024-03-22 |
科辉智药生物科技(深圳)有限公司 |
大环含氮冠醚化合物及其作为蛋白激酶抑制剂的应用
|
|
CN115403568B
(zh)
*
|
2022-09-21 |
2023-09-29 |
中山大学 |
一种喹唑啉类Aurora A共价抑制剂及其制备方法和应用
|
|
US20240317777A1
(en)
*
|
2023-02-23 |
2024-09-26 |
Accutar Biotechnology Inc. |
Novel macrocyclic aminopyrazole compounds as cdk2 inhibitors
|
|
US12161612B2
(en)
|
2023-04-14 |
2024-12-10 |
Neuroderm, Ltd. |
Methods and compositions for reducing symptoms of Parkinson's disease
|
|
WO2026024674A1
(en)
|
2024-07-22 |
2026-01-29 |
Genesis Therapeutics, Inc. |
Methods of treating skp2-associated cancers
|