IL176596A0 - Modified human interferon polypeptides and their uses - Google Patents

Modified human interferon polypeptides and their uses

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Publication number
IL176596A0
IL176596A0 IL176596A IL17659606A IL176596A0 IL 176596 A0 IL176596 A0 IL 176596A0 IL 176596 A IL176596 A IL 176596A IL 17659606 A IL17659606 A IL 17659606A IL 176596 A0 IL176596 A0 IL 176596A0
Authority
IL
Israel
Prior art keywords
modified human
human interferon
interferon polypeptides
polypeptides
modified
Prior art date
Application number
IL176596A
Other languages
English (en)
Original Assignee
Ambrx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambrx Inc filed Critical Ambrx Inc
Publication of IL176596A0 publication Critical patent/IL176596A0/en

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    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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    • A61K38/21Interferons [IFN]
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    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/61Growth hormone [GH], i.e. somatotropin
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    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • C08G65/333Polymers modified by chemical after-treatment with organic compounds containing nitrogen
    • C08G65/33396Polymers modified by chemical after-treatment with organic compounds containing nitrogen having oxygen in addition to nitrogen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875Nucleoproteins
    • GPHYSICS
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
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  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
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  • Virology (AREA)
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  • Food Science & Technology (AREA)
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IL176596A 2004-02-02 2006-06-28 Modified human interferon polypeptides and their uses IL176596A0 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US54152804P 2004-02-02 2004-02-02
US58131404P 2004-06-18 2004-06-18
US58088504P 2004-06-18 2004-06-18
US58117504P 2004-06-18 2004-06-18
US63861604P 2004-12-22 2004-12-22
PCT/US2005/002599 WO2005074524A2 (en) 2004-02-02 2005-01-28 Modified human interferon polypeptides and their uses

Publications (1)

Publication Number Publication Date
IL176596A0 true IL176596A0 (en) 2008-04-13

Family

ID=34842043

Family Applications (3)

Application Number Title Priority Date Filing Date
IL176594A IL176594A0 (en) 2004-02-02 2006-06-28 Modified human four helical bundle polypeptides and their uses
IL176596A IL176596A0 (en) 2004-02-02 2006-06-28 Modified human interferon polypeptides and their uses
IL176595A IL176595A (en) 2004-02-02 2006-06-28 Different human growth hormone polypeptides and their uses

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL176594A IL176594A0 (en) 2004-02-02 2006-06-28 Modified human four helical bundle polypeptides and their uses

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL176595A IL176595A (en) 2004-02-02 2006-06-28 Different human growth hormone polypeptides and their uses

Country Status (15)

Country Link
US (15) US8119603B2 (enExample)
EP (4) EP2327724A3 (enExample)
JP (3) JP4896745B2 (enExample)
KR (3) KR20060130182A (enExample)
CN (1) CN103755800B (enExample)
AT (1) ATE546463T1 (enExample)
AU (5) AU2005211362B2 (enExample)
BR (3) BRPI0507169A (enExample)
CA (3) CA2553035A1 (enExample)
GB (3) GB2429207A (enExample)
IL (3) IL176594A0 (enExample)
MX (3) MXPA06008507A (enExample)
NZ (4) NZ548255A (enExample)
SG (1) SG135176A1 (enExample)
WO (3) WO2005074546A2 (enExample)

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WO2005074546A2 (en) 2004-02-02 2005-08-18 Ambrx, Inc. Modified human growth hormone polypeptides and their uses
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EP1805217A2 (en) * 2004-10-18 2007-07-11 Novo Nordisk A/S Method for the preparation of oxime, thiazolidine, dithiane, dithiolane or hydrazone linked analogues of growth hormone
US7998930B2 (en) 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
EP2314618A3 (en) 2004-11-12 2011-10-19 Xencor Inc. Fc variants with altered binding to FcRn
US8802820B2 (en) 2004-11-12 2014-08-12 Xencor, Inc. Fc variants with altered binding to FcRn
MX2007007587A (es) * 2004-12-22 2007-12-11 Ambrx Inc Formulaciones de la hormona del crecimiento humano que comprenden un aminoacido codificado de manera no natural.
WO2006073846A2 (en) * 2004-12-22 2006-07-13 Ambrx, Inc. Methods for expression and purification of recombinant human growth hormone
KR20070090023A (ko) * 2004-12-22 2007-09-04 암브룩스, 인코포레이티드 변형 인간 성장 호르몬
ZA200704926B (en) * 2004-12-22 2008-12-31 Ambrx Inc Modified human growth hormone
ATE541934T1 (de) 2004-12-22 2012-02-15 Ambrx Inc Zusammensetzungen von aminoacyl-trna-synthetase und verwendungen davon
EP1861125A2 (en) * 2005-03-23 2007-12-05 Nektar Therapeutics Al, Corporation Conjugates of an hgh moiety and peg derivatives
US20080227205A1 (en) * 2005-06-03 2008-09-18 Ambrx, Inc. Incorporation on Non-Naturally Encoded Amino Acids Into Proteins
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