UA76934C2
(en)
*
|
1996-10-04 |
2006-10-16 |
Chugai Pharmaceutical Co Ltd |
Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
|
ES2301198T3
(es)
*
|
1997-06-12 |
2008-06-16 |
Novartis International Pharmaceutical Ltd. |
Polipeptidos artificiales de anticuerpos.
|
AU771224B2
(en)
*
|
1998-07-13 |
2004-03-18 |
Board Of Regents, The University Of Texas System |
Cancer treatment methods using antibodies to aminophospholipids
|
JP2002530081A
(ja)
|
1998-11-18 |
2002-09-17 |
ジェネンテック・インコーポレーテッド |
親抗体より高度な結合親和性を持つ抗体変異体
|
CN101289511A
(zh)
|
2000-04-11 |
2008-10-22 |
杰南技术公司 |
多价抗体及其应用
|
JP4955185B2
(ja)
*
|
2000-06-29 |
2012-06-20 |
アボット・ラボラトリーズ |
二重特異性抗体ならびに作製方法および使用方法
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
US7829084B2
(en)
*
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
DK2163256T3
(da)
|
2001-05-11 |
2015-12-07 |
Ludwig Inst For Cancer Res Ltd |
Specifikke bindende proteiner og anvendelse deraf
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
US20100081792A1
(en)
*
|
2001-06-28 |
2010-04-01 |
Smithkline Beecham Corporation |
Ligand
|
US20060073141A1
(en)
*
|
2001-06-28 |
2006-04-06 |
Domantis Limited |
Compositions and methods for treating inflammatory disorders
|
JP2005289809A
(ja)
*
|
2001-10-24 |
2005-10-20 |
Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) |
突然変異重鎖抗体
|
US20060002935A1
(en)
|
2002-06-28 |
2006-01-05 |
Domantis Limited |
Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor
|
EP1517921B1
(en)
|
2002-06-28 |
2006-06-07 |
Domantis Limited |
Dual specific ligands with increased serum half-life
|
US7696320B2
(en)
*
|
2004-08-24 |
2010-04-13 |
Domantis Limited |
Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
|
US9321832B2
(en)
*
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
US9028822B2
(en)
|
2002-06-28 |
2015-05-12 |
Domantis Limited |
Antagonists against TNFR1 and methods of use therefor
|
EP1539235A2
(en)
|
2002-07-01 |
2005-06-15 |
Human Genome Sciences, Inc. |
Antibodies that specifically bind to reg iv
|
ATE512364T1
(de)
|
2002-08-07 |
2011-06-15 |
Ablynx Nv |
Modulation der blutplättchen-adhäsion basierend auf dem oberflächen-exponierten beta-switch loop des blutplättchen-glycoproteins ib-alpha
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
EP2267032A3
(en)
*
|
2002-11-08 |
2011-11-09 |
Ablynx N.V. |
Method of administering therapeutic polypeptides, and polypeptides therefor
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
WO2004041862A2
(en)
*
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
KR20050086628A
(ko)
*
|
2002-11-15 |
2005-08-30 |
젠맵 에이/에스 |
Cd25에 대한 인간 모노클로날 항체
|
US9498530B2
(en)
|
2002-12-24 |
2016-11-22 |
Rinat Neuroscience Corp. |
Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
|
ZA200504866B
(en)
*
|
2002-12-24 |
2006-11-29 |
Rinat Neuroscience Corp |
Anti-ngf antibodies and methods using same
|
EP1587838B1
(en)
|
2003-01-10 |
2015-04-15 |
Ablynx N.V. |
Therapeutic polypeptides, homologues thereof, fragments thereof and their use in modulating platelet-mediated aggregation
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
ES2527871T3
(es)
*
|
2003-05-01 |
2015-02-02 |
Imclone Llc |
Anticuerpos completamente humanos dirigidos contra el receptor del factor de crecimiento 1 similar a la insulina humana
|
JP5091476B2
(ja)
|
2003-06-27 |
2012-12-05 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
均質な抗体溶液の生成のための疎水性相互作用クロマトグラフィーまたはヒンジ領域改変の使用
|
ES2315664T3
(es)
*
|
2003-06-30 |
2009-04-01 |
Domantis Limited |
Anticuerpos de dominio unico (dab) pegilados.
|
EP1531162A1
(en)
*
|
2003-11-14 |
2005-05-18 |
Heinz Vollmers |
Adenocarcinoma specific antibody SAM-6, and uses thereof
|
US9200061B2
(en)
|
2004-02-06 |
2015-12-01 |
Morpho Sys AG |
Generation and profiling of fully human HuCAL gold®-derived therapeutic antibodies specific for human CD3i
|
MXPA06008700A
(es)
|
2004-02-06 |
2007-01-19 |
Morphosys Ag |
Anticuerpos anti-cd38 humanos y usos para los mismos.
|
EP2168986A3
(en)
*
|
2004-02-19 |
2010-07-28 |
Genentech, Inc. |
CDR-repaired antibodies
|
WO2005118642A2
(en)
*
|
2004-06-01 |
2005-12-15 |
Domantis Limited |
Bispecific fusion antibodies with enhanced serum half-life
|
ATE548387T1
(de)
*
|
2004-06-29 |
2012-03-15 |
Brahms Gmbh |
Neue monoklonale schilddrüsen-stimulierende oder -blockierende antikörper, korrespondierende peptidesquenzen ihrer variablen regionen, und deren verwendung in diagnostik, präventiver und therapeutischer medizin
|
JP2008504356A
(ja)
*
|
2004-06-30 |
2008-02-14 |
ドマンティス リミテッド |
炎症性疾患を治療するための組成物及び方法
|
EP2322554A1
(en)
*
|
2004-06-30 |
2011-05-18 |
Domantis Limited |
Composition comprising an anti-TNF-alpha domain antibody for the treatment of rheumatoid arthritis
|
EP2199801B1
(en)
*
|
2004-07-14 |
2013-05-29 |
The Regents of The University of California |
Biomarkers for early detection of ovarian cancer
|
PT2311874T
(pt)
|
2004-07-22 |
2017-08-25 |
Univ Erasmus Med Ct Rotterdam |
Moléculas de ligação
|
EP1791563A4
(en)
|
2004-07-26 |
2009-07-08 |
Biogen Idec Inc |
ANTI-CD154 ANTIBODIES
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
CN101724071A
(zh)
*
|
2004-10-08 |
2010-06-09 |
杜门蒂斯有限公司 |
抗肿瘤坏死因子受体1的单域抗体及其使用方法
|
EP1799259B1
(en)
*
|
2004-10-12 |
2012-12-05 |
Crucell Holland B.V. |
Binding molecules for the detection of cancer
|
EP1814514A2
(en)
*
|
2004-11-25 |
2007-08-08 |
Unilever Naamloze Vennootschap |
Heavy chain and single domain antibodies
|
US20090111745A1
(en)
*
|
2004-12-02 |
2009-04-30 |
Domantis Limited |
Plad Domain Peptides With Increased Serum Half Life Due To Conjugation To Domain Antibodies
|
GB0521621D0
(en)
|
2005-10-24 |
2005-11-30 |
Domantis Ltd |
Tumor necrosis factor receptor 1 antagonists for treating respiratory diseases
|
AU2005311099B2
(en)
*
|
2004-12-02 |
2012-02-02 |
Domantis Limited |
Bispecific domain antibodies targeting serum albumin and GLP-1 or PYY
|
CN101133084A
(zh)
*
|
2004-12-02 |
2008-02-27 |
多曼蒂斯有限公司 |
采用白细胞介素-1ⅰ型受体拮抗剂治疗呼吸道疾病的方法
|
FR2879605B1
(fr)
|
2004-12-16 |
2008-10-17 |
Centre Nat Rech Scient Cnrse |
Production de formats d'anticorps et applications immunologiques de ces formats
|
ES2557587T3
(es)
|
2004-12-28 |
2016-01-27 |
Innate Pharma |
Anticuerpos monoclonales contra NKG2A
|
EP1838736B1
(en)
*
|
2005-01-05 |
2013-03-06 |
Biogen Idec MA Inc. |
Cripto binding molecules
|
EP3072522B1
(en)
|
2005-01-06 |
2019-04-24 |
Novo Nordisk A/S |
Anti-kir combination treatments and methods
|
WO2006074947A2
(en)
|
2005-01-14 |
2006-07-20 |
Ablynx N.V. |
METHODS AND ASSAYS FOR DISTINGUISHING BETWEEN DIFFERENT FORMS OF DISEASES AND DISORDERS CHARACTERIZED BY THROMBOCYTOPENIA AND/OR BY SPONTANEOUS INTERACTION BETWEEN VON WILLEBRAND FACTOR (vWF) AND PLATELETS
|
JP2008537673A
(ja)
*
|
2005-01-31 |
2008-09-25 |
ジェネンテック・インコーポレーテッド |
抗ephb2抗体とその使用方法
|
PL1853718T3
(pl)
|
2005-02-15 |
2016-01-29 |
Univ Duke |
Przeciwciała anty-CD19 i zastosowania w onkologii
|
JP5167473B2
(ja)
|
2005-03-03 |
2013-03-21 |
コヴェックス・テクノロジーズ・アイルランド・リミテッド |
抗血管新生化合物
|
AU2006224438A1
(en)
*
|
2005-03-18 |
2006-09-21 |
Antonio Cassone |
Antibodies against Candida antigens
|
US8759490B2
(en)
|
2005-03-24 |
2014-06-24 |
Millennium Pharamaceuticals, Inc. |
Antibodies that bind OV064 and methods of use therefor
|
EP3058955B1
(en)
*
|
2005-03-24 |
2019-05-29 |
Millennium Pharmaceuticals, Inc. |
Antibodies that bind ov064 and methods of use therefor
|
EP2377936A3
(en)
|
2005-03-25 |
2012-06-13 |
National Research Council of Canada |
Method for isolation of soluble polypeptides
|
US9493569B2
(en)
|
2005-03-31 |
2016-11-15 |
Chugai Seiyaku Kabushiki Kaisha |
Structural isomers of sc(Fv)2
|
JP5039027B2
(ja)
*
|
2005-04-15 |
2012-10-03 |
ネオジェニックス オンコロジー, インコーポレイテッド |
結腸癌および膵臓癌のための、組換え型モノクローナル抗体および対応する抗原
|
EP2444421A1
(en)
*
|
2005-04-26 |
2012-04-25 |
Pfizer Inc. |
P-Cadherin antibodies
|
JP5047947B2
(ja)
|
2005-05-05 |
2012-10-10 |
デューク ユニバーシティ |
自己免疫疾患のための抗cd19抗体治療
|
WO2006122787A1
(en)
|
2005-05-18 |
2006-11-23 |
Ablynx Nv |
Serum albumin binding proteins
|
KR101414438B1
(ko)
|
2005-05-20 |
2014-07-10 |
아블린쓰 엔.브이. |
폰 빌레브란트 인자에 대한 단일 도메인 vhh 항체
|
DE102005023617A1
(de)
|
2005-05-21 |
2006-11-23 |
Aspre Ag |
Verfahren zum Mischen von Farben in einem Display
|
WO2006129843A2
(en)
*
|
2005-05-31 |
2006-12-07 |
Canon Kabushiki Kaisha |
Bispecific capturing molecule
|
JP2007008925A
(ja)
*
|
2005-05-31 |
2007-01-18 |
Canon Inc |
標的物質捕捉分子
|
WO2006129828A2
(en)
|
2005-05-31 |
2006-12-07 |
Canon Kabushiki Kaisha |
Target substance capturing molecule
|
AU2006256041B2
(en)
|
2005-06-10 |
2012-03-29 |
Chugai Seiyaku Kabushiki Kaisha |
Stabilizer for protein preparation comprising meglumine and use thereof
|
KR101360671B1
(ko)
|
2005-06-10 |
2014-02-07 |
추가이 세이야쿠 가부시키가이샤 |
sc(Fv)2를 함유하는 의약조성물
|
JP2009501141A
(ja)
|
2005-06-17 |
2009-01-15 |
イムクローン システムズ インコーポレイテッド |
転移性骨癌の治療のための受容体アンタゴニスト
|
ES2460517T3
(es)
|
2005-07-25 |
2014-05-13 |
Emergent Product Development Seattle, Llc |
Reducción de células b mediante el uso de moléculas de unión específica a cd37 y de unión específica a cd20
|
ZA200802246B
(en)
*
|
2005-08-15 |
2009-09-30 |
Arana Therapeutics Ltd |
Engineered antibodies with new world primate framework regions
|
CA2625951A1
(en)
*
|
2005-09-01 |
2007-03-08 |
National Research Council Of Canada |
Anti-apoptotic protein antibodies
|
EP3284756B1
(en)
|
2005-10-12 |
2021-05-05 |
MorphoSys AG |
Generation and profiling of fully human hucal gold-derived therapeutic antibodies specific for human cd38
|
WO2007056441A2
(en)
*
|
2005-11-07 |
2007-05-18 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
|
PE20070684A1
(es)
|
2005-11-14 |
2007-08-06 |
Amgen Inc |
MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
|
BRPI0618705B8
(pt)
|
2005-11-14 |
2021-05-25 |
Labrys Biologics Inc |
anticorpos antagonistas humanizados direcionados contra peptídeo relacionado ao gene da calcitonina, composição farmacêutica e uso dos mesmos
|
CN117903302A
(zh)
|
2005-11-30 |
2024-04-19 |
Abbvie 公司 |
抗-Aβ球聚体抗体,其相关产品,生产所述抗体的方法,所述抗体的应用以及使用方法
|
PL1976877T5
(pl)
|
2005-11-30 |
2017-09-29 |
Abbvie Inc |
Przeciwciała monoklonalne przeciwko białku amyloidu beta oraz ich zastosowania
|
CN101466734A
(zh)
*
|
2005-12-01 |
2009-06-24 |
杜门蒂斯有限公司 |
与白细胞介素-1受体1型结合的竞争性域抗体形式
|
JP2009519011A
(ja)
*
|
2005-12-01 |
2009-05-14 |
ドマンティス リミテッド |
インターロイキン1受容体1型に結合する非競合ドメイン抗体フォーマット
|
WO2007066109A1
(en)
*
|
2005-12-06 |
2007-06-14 |
Domantis Limited |
Bispecific ligands with binding specificity to cell surface targets and methods of use therefor
|
EA013878B1
(ru)
*
|
2005-12-06 |
2010-08-30 |
Домантис Лимитед |
Лиганды, имеющие специфичность связывания в отношении рецептора эпидермального фактора роста (egfr) и/или сосудистого эндотелиального фактора роста (vegf), и способы их применения
|
EP3309170B1
(en)
|
2005-12-15 |
2019-05-22 |
Genentech, Inc. |
Polyubiquitin antibodies
|
ES2291103B1
(es)
|
2005-12-30 |
2009-02-01 |
Universidad Publica De Navarra |
Metodo y sistema de control del convertidor de una instalacion de generacion electrica conectada a una red electrica ante la presencia de huecos de tension en dicha red.
|
EP1806365A1
(en)
|
2006-01-05 |
2007-07-11 |
Boehringer Ingelheim International GmbH |
Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them
|
WO2007085815A2
(en)
*
|
2006-01-24 |
2007-08-02 |
Domantis Limited |
Ligands that bind il-4 and/or il-13
|
JP5259423B2
(ja)
|
2006-02-01 |
2013-08-07 |
セファロン・オーストラリア・ピーティーワイ・リミテッド |
ドメイン抗体構築物
|
JP5198289B2
(ja)
*
|
2006-02-03 |
2013-05-15 |
イムクローン・リミテッド・ライアビリティ・カンパニー |
前立腺癌の治療用アジュバントとしてのigf−irアンタゴニスト
|
US8389688B2
(en)
|
2006-03-06 |
2013-03-05 |
Aeres Biomedical, Ltd. |
Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
US20100226920A1
(en)
*
|
2006-03-27 |
2010-09-09 |
Ablynx N.V. |
Medical delivery device for therapeutic proteins based on single domain antibodies
|
US9670269B2
(en)
|
2006-03-31 |
2017-06-06 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of modifying antibodies for purification of bispecific antibodies
|
US20070269422A1
(en)
*
|
2006-05-17 |
2007-11-22 |
Ablynx N.V. |
Serum albumin binding proteins with long half-lives
|
US20070274985A1
(en)
*
|
2006-05-26 |
2007-11-29 |
Stefan Dubel |
Antibody
|
GB0611116D0
(en)
|
2006-06-06 |
2006-07-19 |
Oxford Genome Sciences Uk Ltd |
Proteins
|
AU2007257949B2
(en)
*
|
2006-06-12 |
2013-08-01 |
Centocor, Inc. |
Method for detecting IL-16 activity and modulation of IL-16 activity based on rantes proxy levels
|
KR101571027B1
(ko)
|
2006-06-12 |
2015-11-23 |
이머전트 프로덕트 디벨롭먼트 시애틀, 엘엘씨 |
효과기 기능을 갖는 단일쇄 다가 결합 단백질
|
MX2008015830A
(es)
|
2006-06-30 |
2009-01-09 |
Novo Nordisk As |
Anticuerpos anti-nkg2a y usos de los mismos.
|
KR101429783B1
(ko)
*
|
2006-07-12 |
2014-08-18 |
가부시키가이샤 진 테크노 사이언스 |
항 인간 α9 인테그린 항체와 그 용도
|
EA201201533A1
(ru)
*
|
2006-08-18 |
2014-11-28 |
Новартис Аг |
Prlr-специфическое антитело и его применения
|
CA2661042C
(en)
|
2006-08-18 |
2012-12-11 |
Armagen Technologies, Inc. |
Agents for blood-brain barrier delivery
|
PL2059533T3
(pl)
|
2006-08-30 |
2013-04-30 |
Genentech Inc |
Przeciwciała wieloswoiste
|
MX2009002418A
(es)
|
2006-09-05 |
2009-04-23 |
Medarex Inc |
Anticuerpos para las proteinas morfogenicas oseas y receptores de estas y metodos para su uso.
|
EP1900752A1
(en)
*
|
2006-09-15 |
2008-03-19 |
DOMPE' pha.r.ma s.p.a. |
Human anti-folate receptor alpha antibodies and antibody fragments for the radioimmunotherapy of ovarian carcinoma
|
GB0619291D0
(en)
*
|
2006-09-29 |
2006-11-08 |
Ucb Sa |
Altered antibodies
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
MX2009003306A
(es)
|
2006-10-02 |
2009-04-23 |
Medarex Inc |
Anticuerpos humanos que se unen a cxcr4 y sus usos.
|
JP2010505435A
(ja)
*
|
2006-10-11 |
2010-02-25 |
アブリンクス エン.ヴェー. |
本質的にpHに非依存的に血清タンパク質に結合するアミノ酸配列、それを含む化合物、およびその使用
|
CN101594883B
(zh)
*
|
2006-10-12 |
2018-04-10 |
中外制药株式会社 |
使用抗ereg抗体的癌症的诊断和治疗
|
GB0621513D0
(en)
|
2006-10-30 |
2006-12-06 |
Domantis Ltd |
Novel polypeptides and uses thereof
|
AU2007318912B2
(en)
|
2006-11-10 |
2011-03-03 |
Covx Technologies Ireland Limited |
Anti-angiogenic compounds
|
CN103073641B
(zh)
*
|
2006-11-10 |
2015-01-21 |
株式会社立富泰克 |
在体内具有抗肿瘤活性的抗人Dlk-1抗体
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
CN101626782B
(zh)
|
2006-12-01 |
2013-03-27 |
梅达雷克斯公司 |
结合cd22的人抗体及其用途
|
CL2007003622A1
(es)
|
2006-12-13 |
2009-08-07 |
Medarex Inc |
Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales.
|
RU2448979C2
(ru)
|
2006-12-14 |
2012-04-27 |
Ридженерон Фармасьютикалз, Инк. |
Антитела человека к дельта-подобному лиганду-4 человека
|
EP2097534A4
(en)
|
2006-12-14 |
2010-05-12 |
Medarex Inc |
HUMAN ANTIBODIES BINDING TO CD70 AND USES THEREOF
|
US20100111852A1
(en)
*
|
2006-12-14 |
2010-05-06 |
Forerunner Pharma Research Co., Ltd. |
Anti-Claudin 3 Monoclonal Antibody and Treatment and Diagnosis of Cancer Using the Same
|
WO2008074840A2
(en)
|
2006-12-19 |
2008-06-26 |
Ablynx N.V. |
Amino acid sequences directed against a metalloproteinase from the adam family and polypeptides comprising the same for the treatment of adam-related diseases and disorders
|
EP2557090A3
(en)
|
2006-12-19 |
2013-05-29 |
Ablynx N.V. |
Amino acid sequences directed against GPCRs and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
|
EP2114443A4
(en)
*
|
2006-12-29 |
2011-08-10 |
Abbott Lab |
IL-1A / IL-1B ANTIBODY WITH DOUBLE SPECIFICITY
|
ES2609094T3
(es)
|
2007-01-25 |
2017-04-18 |
Dana-Farber Cancer Institute, Inc. |
Uso de anticuerpos anti-EGFR en el tratamiento de enfermedades mediadas por un EGFR mutante
|
EP2647388A1
(en)
|
2007-02-16 |
2013-10-09 |
Merrimack Pharmaceuticals, Inc. |
Antibodies Against ERBB3 and Uses Thereof
|
WO2008104803A2
(en)
|
2007-02-26 |
2008-09-04 |
Oxford Genome Sciences (Uk) Limited |
Proteins
|
DK2447719T3
(da)
|
2007-02-26 |
2016-10-10 |
Oxford Biotherapeutics Ltd |
Proteiner
|
EP2486928A1
(en)
|
2007-02-27 |
2012-08-15 |
Abbott GmbH & Co. KG |
Method for the treatment of amyloidoses
|
EP2121920B1
(en)
*
|
2007-03-01 |
2011-08-24 |
Symphogen A/S |
Method for cloning cognate antibodies
|
CN101688229B
(zh)
|
2007-03-15 |
2013-06-12 |
路德维格癌症研究所 |
包含egfr抗体和src抑制剂的组合物及其在制备用于治疗哺乳动物癌症的药物中的用途
|
CA2681530C
(en)
*
|
2007-03-22 |
2017-03-28 |
Biogen Idec Ma Inc. |
Binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind cd154
|
AU2008230795B2
(en)
|
2007-03-27 |
2014-05-29 |
Bioassets, Llc |
Constructs and libraries comprising antibody surrogate light chain sequences
|
WO2008122039A2
(en)
*
|
2007-04-02 |
2008-10-09 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Selenocysteine mediated hybrid antibody molecules
|
CA2722304A1
(en)
*
|
2007-04-23 |
2009-02-19 |
Sudhir Paul |
Immunoglobulins directed to bacterial, viral and endogeneous polypeptides
|
AU2008246442B2
(en)
*
|
2007-05-04 |
2014-07-03 |
Technophage, Investigacao E Desenvolvimento Em Biotecnologia, Sa |
Engineered rabbit antibody variable domains and uses thereof
|
WO2008137915A2
(en)
|
2007-05-07 |
2008-11-13 |
Medimmune, Llc |
Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
DK2164992T3
(da)
*
|
2007-05-30 |
2016-08-15 |
Lpath Inc |
Sammensætninger og fremgangsmåder til binding af lysophosphatidsyre
|
US9163091B2
(en)
|
2007-05-30 |
2015-10-20 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
AU2008262384B9
(en)
|
2007-06-05 |
2014-11-27 |
Yale University |
Inhibitors of receptor tyrosine kinases and methods of use thereof
|
GB0724331D0
(en)
*
|
2007-12-13 |
2008-01-23 |
Domantis Ltd |
Compositions for pulmonary delivery
|
CA2688433A1
(en)
|
2007-06-06 |
2008-12-11 |
Domantis Limited |
Methods for selecting protease resistant polypeptides
|
PE20090368A1
(es)
|
2007-06-19 |
2009-04-28 |
Boehringer Ingelheim Int |
Anticuerpos anti-igf
|
EP2997976A1
(en)
|
2007-07-27 |
2016-03-23 |
Armagen Technologies, Inc. |
Methods and compositions for increasing alpha-l-iduronidase activity in the cns
|
US9283276B2
(en)
|
2007-08-14 |
2016-03-15 |
Ludwig Institute For Cancer Research Ltd. |
Monoclonal antibody 175 targeting the EGF receptor and derivatives and uses thereof
|
CN101842387B
(zh)
*
|
2007-09-26 |
2014-05-07 |
Ucb医药有限公司 |
双特异性抗体融合物
|
KR20100091170A
(ko)
|
2007-11-02 |
2010-08-18 |
노파르티스 아게 |
저밀도-지단백질 수용체-관련 단백질 6 (lrp6)을 조정하기 위한 분자 및 방법
|
KR20100100912A
(ko)
|
2007-11-27 |
2010-09-15 |
더 유니버시티 오브 브리티쉬 콜롬비아 |
관절염의 진단과 치료를 위한 14-3-3 에타 항체 및 이의 용도
|
BRPI0819656A2
(pt)
|
2007-11-27 |
2015-06-23 |
Ablynx Nv |
Seqüências de aminoácidos contras citocinas heterodiméricas e/ou seus receptores e polipeptídeos compreendendo as mesmas
|
EP3239178A1
(en)
|
2007-12-14 |
2017-11-01 |
Bristol-Myers Squibb Company |
Binding molecules to the human ox40 receptor
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
US8574577B2
(en)
|
2008-01-03 |
2013-11-05 |
The Scripps Research Institute |
VEGF antibodies comprising modular recognition domains
|
US8557243B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
EFGR antibodies comprising modular recognition domains
|
US8454960B2
(en)
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
US20110189206A1
(en)
|
2008-01-03 |
2011-08-04 |
Barbas Iii Carlos F |
Antibody Targeting Through a Modular Recognition Domain
|
US8557242B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
ERBB2 antibodies comprising modular recognition domains
|
WO2009089295A2
(en)
*
|
2008-01-07 |
2009-07-16 |
Government Of The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Anti-hiv domain antibodies and method of making and using same
|
CN101918450A
(zh)
*
|
2008-01-11 |
2010-12-15 |
国立大学法人东京大学 |
抗cldn6抗体
|
CN102015769B
(zh)
*
|
2008-01-17 |
2014-12-10 |
Irm责任有限公司 |
改进的抗-trkb抗体
|
US8133488B2
(en)
|
2008-01-18 |
2012-03-13 |
Genentech, Inc. |
Methods and compositions for targeting polyubiquitin
|
US8796427B2
(en)
|
2008-01-24 |
2014-08-05 |
Novo Nordisk A/S |
Humanized anti-human NKG2A monoclonal antibody
|
EP2265287B1
(en)
|
2008-03-04 |
2018-09-05 |
Teva Pharmaceuticals International GmbH |
Methods of treating chronic pain
|
EP2247616A2
(en)
|
2008-03-05 |
2010-11-10 |
Ablynx N.V. |
Novel antigen binding dimer-complexes, methods of making and uses thereof
|
ES2527521T3
(es)
*
|
2008-03-17 |
2015-01-26 |
Livtech Inc. |
Anticuerpos antihumanos frente a Dlk-1 que tienen actividad antitumoral
|
MX2010010480A
(es)
*
|
2008-03-25 |
2010-10-15 |
Schering Corp |
Metodos de tratamiento o prevencion del cancer colorrectal.
|
CA2719201A1
(en)
|
2008-03-28 |
2009-10-01 |
Sea Lane Biotechnologies, Llc. |
Neutralizing molecules to viral antigens
|
JP5555223B2
(ja)
*
|
2008-04-02 |
2014-07-23 |
マクロジェニクス,インコーポレーテッド |
HER2/neu特異的抗体およびその使用方法
|
EP2260058A2
(en)
|
2008-04-07 |
2010-12-15 |
Ablynx N.V. |
Single variable domains against the notch pathways
|
CN102099377A
(zh)
|
2008-04-11 |
2011-06-15 |
新兴产品开发西雅图有限公司 |
Cd37免疫治疗剂及其与双功能化学治疗剂的联合
|
US8217140B2
(en)
|
2008-04-17 |
2012-07-10 |
Ablynx N.V. |
Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same
|
ES2704835T3
(es)
|
2008-04-28 |
2019-03-20 |
Humanigen Inc |
Anticuerpos contra el factor estimulante de colonias de granulocitos y macrófagos
|
SI2285408T1
(sl)
|
2008-06-05 |
2019-02-28 |
Ablynx N.V. |
Aminokislinska zaporedja usmerjena proti proteinom ovojnicam virusa in polipeptidi, ki zaporedja vsebujejo za zdravljenje virusnih bolezni
|
CA2728733A1
(en)
|
2008-06-18 |
2009-12-23 |
California Institute Of Technology |
Multi-ligand capture agents and related compositions, methods and systems
|
US8444976B2
(en)
|
2008-07-02 |
2013-05-21 |
Argen-X B.V. |
Antigen binding polypeptides
|
EP2700651B1
(en)
|
2008-07-18 |
2019-04-10 |
Bristol-Myers Squibb Company |
Compositions monovalent for CD28 binding and methods of use
|
JP5924937B2
(ja)
|
2008-07-25 |
2016-05-25 |
エックス−ボディ インコーポレイテッド |
タンパク質スクリーニング法
|
PE20120015A1
(es)
|
2008-08-15 |
2012-01-26 |
Merrimack Pharmaceuticals Inc |
Metodos y sistemas para predecir la respuesta de las celulas tumorales a un agente terapeutico
|
WO2010027767A1
(en)
*
|
2008-08-27 |
2010-03-11 |
Schering Corporation |
Engineered anti-il-23r antibodies
|
US8193321B2
(en)
|
2008-09-03 |
2012-06-05 |
Genentech, Inc. |
Multispecific antibodies
|
WO2010027488A2
(en)
*
|
2008-09-04 |
2010-03-11 |
Vet Therapeutics, Inc. |
Monoclonal antibodies
|
WO2010035012A1
(en)
*
|
2008-09-26 |
2010-04-01 |
Ucb Pharma S.A. |
Biological products
|
WO2010037838A2
(en)
*
|
2008-10-01 |
2010-04-08 |
Micromet Ag |
Cross-species-specific single domain bispecific single chain antibody
|
NZ592054A
(en)
*
|
2008-10-13 |
2013-06-28 |
Inst Research In Biomedicine |
Dengue virus neutralizing antibodies and uses thereof
|
EP3011953A1
(en)
|
2008-10-29 |
2016-04-27 |
Ablynx N.V. |
Stabilised formulations of single domain antigen binding molecules
|
WO2010056550A1
(en)
|
2008-10-29 |
2010-05-20 |
Wyeth Llc |
Methods for purification of single domain antigen binding molecules
|
EP2358392B1
(en)
|
2008-11-12 |
2019-01-09 |
MedImmune, LLC |
Antibody formulation
|
PE20120415A1
(es)
|
2008-12-12 |
2012-05-09 |
Boehringer Ingelheim Int |
Anticuerpos anti-igf
|
ES2701649T3
(es)
|
2009-01-14 |
2019-02-25 |
Ablynx Nv |
Administración pulmonar de dominios variables individuales de inmunoglobulina y constructos de los mismos
|
US20120058131A1
(en)
|
2009-01-21 |
2012-03-08 |
Oxford Biotherapeutics Ltd |
Pta089 protein
|
US20100260752A1
(en)
|
2009-01-23 |
2010-10-14 |
Biosynexus Incorporated |
Opsonic and protective antibodies specific for lipoteichoic acid of gram positive bacteria
|
WO2010088444A1
(en)
*
|
2009-01-29 |
2010-08-05 |
Medimmune, Llc |
Human anti-il-6 antibodies with extended in vivo half-life and their use in treatment of oncology, autoimmune diseases and inflammatory diseases
|
WO2010088739A1
(en)
*
|
2009-02-09 |
2010-08-12 |
Patrys Limited |
Sam-6 variants, target and methods of use
|
EA022925B1
(ru)
|
2009-02-19 |
2016-03-31 |
Глаксо Груп Лимитед |
Улучшенные полипептиды, вариабельные домены антител и антагонисты против tnfr1
|
CN102405232B
(zh)
|
2009-02-19 |
2015-08-19 |
葛兰素集团有限公司 |
改良的抗血清清蛋白结合变体
|
SG173489A1
(en)
|
2009-02-19 |
2011-09-29 |
Glaxo Group Ltd |
Improved anti-serum albumin binding variants
|
EP2401298A1
(en)
|
2009-02-24 |
2012-01-04 |
Glaxo Group Limited |
Antigen-binding constructs
|
ES2639026T3
(es)
|
2009-03-05 |
2017-10-25 |
Oxford Biotherapeutics Ltd. |
Anticuerpos totalmente humanos específicos para CADM1
|
EP2403873A1
(en)
|
2009-03-05 |
2012-01-11 |
Ablynx N.V. |
Novel antigen binding dimer-complexes, methods of making/avoiding and uses thereof
|
CA2748889A1
(en)
|
2009-03-18 |
2010-09-23 |
Armagen Technologies, Inc. |
Compositions and methods for blood-brain barrier delivery of igg-decoy receptor fusion proteins
|
MA33198B1
(fr)
*
|
2009-03-20 |
2012-04-02 |
Genentech Inc |
Anticorps anti-her di-spécifiques
|
US8569460B2
(en)
|
2009-03-25 |
2013-10-29 |
Vet Therapeutics, Inc. |
Antibody constant domain regions and uses thereof
|
WO2010112193A1
(en)
*
|
2009-04-02 |
2010-10-07 |
Roche Glycart Ag |
Multispecific antibodies comprising full length antibodies and single chain fab fragments
|
PT2417156E
(pt)
|
2009-04-07 |
2015-04-29 |
Roche Glycart Ag |
Anticorpos trivalentes, biespecíficos
|
CN102388069B
(zh)
|
2009-04-10 |
2016-01-20 |
埃博灵克斯股份有限公司 |
用于治疗il-6r相关疾病和病症的改进的针对il-6r的氨基酸序列和包含其的多肽
|
UA108201C2
(xx)
|
2009-04-20 |
2015-04-10 |
|
Антитіла, специфічні для кадгерину-17
|
WO2010122090A1
(en)
|
2009-04-24 |
2010-10-28 |
Glaxo Group Limited |
Fgfr1c antibody combinations
|
EP2430047B1
(en)
|
2009-05-13 |
2018-03-28 |
i2 Pharmaceuticals, Inc. |
Neutralizing molecules to influenza viruses
|
JP5808052B2
(ja)
|
2009-05-29 |
2015-11-10 |
中外製薬株式会社 |
Egfファミリーリガンドのアンタゴニストを成分とする医薬組成物
|
RU2016103067A
(ru)
|
2009-06-05 |
2018-11-20 |
Аблинкс Нв |
Улучшенные аминокислотные последовательности, направленные против респираторно-синцитиального вируса человека (hrsv), и полипептиды, включающие такие последовательности, для профилактики и/или лечения инфекций дыхательных путей
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
EP2448966B1
(en)
*
|
2009-07-03 |
2018-11-14 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
EP2453920A2
(en)
|
2009-07-16 |
2012-05-23 |
Glaxo Group Limited |
Antagonists, uses & methods for partially inhibiting tnfr1
|
CA2768462A1
(en)
|
2009-07-16 |
2011-01-20 |
Glaxo Group Ltd. |
Improved anti-serum albumin binding single variable domains
|
BR112012001977A2
(pt)
|
2009-07-29 |
2017-01-31 |
Glaxo Group Ltd |
domínio variável único de imunoglobulina, polipeptídeo isolado, ligante, proteína de fusão, ácido nucleico isolado, molécula de ácido nucleico isolado, vetor, célula hospedeira, métodos para produzir um polipeptídeo e para tratar e/ou prevenir uma condição, composição farmacêutica, uso de um domínio variável único, e, dispositivo de dispensação pulmonar.
|
EP2470207A1
(en)
|
2009-08-28 |
2012-07-04 |
Rinat Neuroscience Corporation |
Methods for treating visceral pain by administering antagonist antibodies directed against calcitonin gene-related peptide
|
NZ598524A
(en)
|
2009-08-29 |
2014-06-27 |
Abbvie Inc |
Therapeutic dll4 binding proteins
|
SG179196A1
(en)
|
2009-09-16 |
2012-04-27 |
Genentech Inc |
Coiled coil and/or tether containing protein complexes and uses thereof
|
EP2480661A1
(en)
|
2009-09-24 |
2012-08-01 |
UCB Pharma, S.A. |
Bacterial host strain
|
GB201005063D0
(en)
|
2010-03-25 |
2010-05-12 |
Ucb Pharma Sa |
Biological products
|
AU2010303415B2
(en)
|
2009-10-07 |
2015-02-19 |
Macrogenics, Inc. |
Fc region-containing polypeptides that exhibit improved effector function due to alterations of the extent of fucosylation, and methods for their use
|
HUE044865T2
(hu)
|
2009-10-09 |
2019-11-28 |
Armagen Inc |
Eljárások és készítmények a központi idegrendszerben iduronát-2-szulfatáz-aktivitás növelésére
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
US20120231004A1
(en)
|
2009-10-13 |
2012-09-13 |
Oxford Biotherapeutic Ltd. |
Antibodies
|
US8577467B2
(en)
|
2011-09-30 |
2013-11-05 |
Nyxoah SA |
Apparatus and method for controlling energy delivery as a function of degree of coupling
|
UA107200C2
(uk)
|
2009-10-27 |
2014-12-10 |
Ґлаксо Ґруп Лімітед |
ОДИНИЧНИЙ ВАРІАБЕЛЬНИЙ ДОМЕН ІМУНОГЛОБУЛІНУ ПРОТИ РЕЦЕПТОРА ТИПУ 1 TNFα
|
US20120282177A1
(en)
|
2009-11-02 |
2012-11-08 |
Christian Rohlff |
ROR1 as Therapeutic and Diagnostic Target
|
JP2013509869A
(ja)
|
2009-11-05 |
2013-03-21 |
ノバルティス アーゲー |
線維症の進行の予測用バイオマーカー
|
US9644022B2
(en)
|
2009-11-30 |
2017-05-09 |
Ablynx N.V. |
Amino acid sequences directed against human respiratory syncytial virus (HRSV) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
|
DK2954779T3
(da)
|
2009-12-10 |
2019-05-13 |
Regeneron Pharma |
Mus, der frembringer tungkædeantistoffer
|
US8962807B2
(en)
|
2009-12-14 |
2015-02-24 |
Ablynx N.V. |
Single variable domain antibodies against OX40L, constructs and therapeutic use
|
US9315581B2
(en)
*
|
2009-12-23 |
2016-04-19 |
A Vipep Pty Limited |
Immuno-conjugates and methods for producing them
|
WO2011083141A2
(en)
|
2010-01-08 |
2011-07-14 |
Ablynx Nv |
Method for generation of immunoglobulin sequences by using lipoprotein particles
|
GB201000590D0
(en)
|
2010-01-14 |
2010-03-03 |
Ucb Pharma Sa |
Bacterial host strain
|
GB201000591D0
(en)
|
2010-01-14 |
2010-03-03 |
Ucb Pharma Sa |
Bacterial hoist strain
|
GB201000587D0
(en)
|
2010-01-14 |
2010-03-03 |
Ucb Pharma Sa |
Bacterial hoist strain
|
SG10201604093XA
(en)
|
2010-01-15 |
2016-07-28 |
Kirin Amgen Inc |
Antibody formulation and therapeutic regimens
|
TWI513466B
(zh)
|
2010-01-20 |
2015-12-21 |
Boehringer Ingelheim Int |
抗凝血劑解毒劑
|
EP2531523A1
(en)
|
2010-02-05 |
2012-12-12 |
Ablynx N.V. |
Peptides capable of binding to serum albumin and compounds, constructs and polypeptides comprising the same
|
IN2012DN06588A
(da)
|
2010-02-10 |
2015-10-23 |
Novartis Ag |
|
US9120855B2
(en)
|
2010-02-10 |
2015-09-01 |
Novartis Ag |
Biologic compounds directed against death receptor 5
|
MX341687B
(es)
|
2010-02-10 |
2016-08-30 |
Immunogen Inc |
"anticuerpos cd20 y su utilización".
|
WO2011098518A2
(en)
|
2010-02-11 |
2011-08-18 |
Ablynx Nv |
Delivery of immunoglobulin variable domains and constructs thereof
|
CN105037543B
(zh)
|
2010-03-02 |
2020-11-03 |
Abbvie 公司 |
治疗性dll4结合蛋白
|
US9616120B2
(en)
|
2010-03-04 |
2017-04-11 |
Vet Therapeutics, Inc. |
Monoclonal antibodies directed to CD20
|
US8652470B2
(en)
|
2010-03-04 |
2014-02-18 |
Vet Therapeutics, Inc. |
Monoclonal antibodies directed to CD52
|
DK2544680T3
(da)
|
2010-03-11 |
2015-04-27 |
Merrimack Pharmaceuticals Inc |
Anvendelse af erbb3-hæmmere i behandlingen af triple-negativ brystcancer
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
CA2796339C
(en)
|
2010-04-15 |
2020-03-31 |
Abbott Laboratories |
Amyloid-beta binding proteins
|
CA2793503A1
(en)
|
2010-04-15 |
2011-10-20 |
Genentech, Inc. |
Anti-polyubiquitin antibodies and methods of use
|
EP2560992A2
(en)
|
2010-04-21 |
2013-02-27 |
Glaxo Group Limited |
Binding domains
|
AU2011249782B2
(en)
|
2010-05-06 |
2014-10-02 |
Novartis Ag |
Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (LRP6) multivalent antibodies
|
BR112012028306A2
(pt)
|
2010-05-06 |
2020-11-03 |
Novartis Ag |
anticorpos para proteína 6 relacionada com lipoproteína de baixa densidade (lrp6) e seus fragmentos, seu uso, ácidos nucléicos, vetores, bem como composições farmacêuticas e combinações
|
US9040668B2
(en)
|
2010-05-20 |
2015-05-26 |
Glaxo Group Limited |
Anti-serum albumin binding variants
|
CN102906118B
(zh)
|
2010-05-20 |
2017-07-28 |
埃博灵克斯股份有限公司 |
与her3相关的生物材料
|
WO2011163401A2
(en)
|
2010-06-22 |
2011-12-29 |
Neogenix Oncology, Inc. |
Colon and pancreas cancer specific antigens and antibodies
|
WO2011161263A1
(en)
|
2010-06-25 |
2011-12-29 |
Ablynx Nv |
Pharmaceutical compositions for cutaneous administration
|
WO2012009705A1
(en)
|
2010-07-15 |
2012-01-19 |
Zyngenia, Inc. |
Ang-2 binding complexes and uses thereof
|
AU2011277983C1
(en)
|
2010-07-16 |
2016-09-29 |
Ablynx Nv |
Modified single domain antigen binding molecules and uses thereof
|
GB201012599D0
(en)
|
2010-07-27 |
2010-09-08 |
Ucb Pharma Sa |
Process for purifying proteins
|
NZ707327A
(en)
|
2010-08-02 |
2017-01-27 |
Regeneron Pharma |
Mice that make binding proteins comprising vl domains
|
AR082461A1
(es)
|
2010-08-03 |
2012-12-12 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
AU2011288412A1
(en)
|
2010-08-13 |
2013-02-21 |
Medimmune Limited |
Monomeric polypeptides comprising variant Fc regions and methods of use
|
JP2013538566A
(ja)
|
2010-08-13 |
2013-10-17 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
改良された抗血清アルブミン結合変異体
|
CA2808187A1
(en)
|
2010-08-14 |
2012-02-23 |
Abbvie Inc. |
Amyloid-beta binding proteins
|
WO2012022734A2
(en)
|
2010-08-16 |
2012-02-23 |
Medimmune Limited |
Anti-icam-1 antibodies and methods of use
|
PT2606070T
(pt)
|
2010-08-20 |
2017-03-31 |
Novartis Ag |
Anticorpos para o recetor 3 do fator de crescimento epidérmico (her3)
|
GB201014033D0
(en)
|
2010-08-20 |
2010-10-06 |
Ucb Pharma Sa |
Biological products
|
KR20130055663A
(ko)
|
2010-08-20 |
2013-05-28 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
개선된 항-혈청 알부민 결합 변이체
|
JP5758004B2
(ja)
|
2010-08-24 |
2015-08-05 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
ジスルフィドによって安定化されたFv断片を含む二重特異性抗体
|
RU2551963C2
(ru)
|
2010-09-09 |
2015-06-10 |
Пфайзер Инк. |
Молекулы, связывающиеся с 4-1вв
|
WO2012062713A1
(en)
|
2010-11-08 |
2012-05-18 |
Novartis Ag |
Cxcr2 binding polypeptides
|
JP6173216B2
(ja)
|
2010-11-26 |
2017-08-02 |
モレキュラー・パートナーズ・アーゲーMolecular Partners Ag |
設計アンキリンリピートタンパク質のための改善されたキャッピングモジュール
|
EP4303236A3
(en)
*
|
2010-11-30 |
2024-03-20 |
Chugai Seiyaku Kabushiki Kaisha |
Cytotoxicity-inducing therapeutic agent
|
US9884909B2
(en)
|
2010-12-01 |
2018-02-06 |
Alderbio Holdings Llc |
Anti-NGF compositions and use thereof
|
US11214610B2
(en)
|
2010-12-01 |
2022-01-04 |
H. Lundbeck A/S |
High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
|
EP2646467A2
(en)
|
2010-12-01 |
2013-10-09 |
Glaxo Group Limited |
Improved anti-serum albumin binding single variable domains
|
US9539324B2
(en)
|
2010-12-01 |
2017-01-10 |
Alderbio Holdings, Llc |
Methods of preventing inflammation and treating pain using anti-NGF compositions
|
CN103619879A
(zh)
|
2010-12-01 |
2014-03-05 |
奥尔德生物控股有限责任公司 |
抗ngf组合物及其用途
|
US9078878B2
(en)
|
2010-12-01 |
2015-07-14 |
Alderbio Holdings Llc |
Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
|
US9067988B2
(en)
|
2010-12-01 |
2015-06-30 |
Alderbio Holdings Llc |
Methods of preventing or treating pain using anti-NGF antibodies
|
WO2012085111A1
(en)
|
2010-12-23 |
2012-06-28 |
F. Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
AU2011353197B2
(en)
*
|
2010-12-27 |
2017-04-20 |
Apo-T B.V. |
A cross linking polypeptide comprising an hexameric single chain antibody binding MHC-MAGE complex that induces apoptosis
|
JP6062375B2
(ja)
|
2011-01-06 |
2017-01-18 |
グラクソ グループ リミテッドGlaxo Group Limited |
Tgf−ベータ受容体iiに結合するリガンド
|
JP2014505698A
(ja)
|
2011-02-02 |
2014-03-06 |
グラクソ グループ リミテッド |
新規抗原結合タンパク質
|
US20140088019A1
(en)
|
2011-02-11 |
2014-03-27 |
Zyngenia, Inc. |
Monovalent and Multivalent Multispecific Complexes and Uses Thereof
|
CA2824824A1
(en)
|
2011-02-28 |
2012-09-07 |
F. Hoffmann-La Roche Ag |
Monovalent antigen binding proteins
|
CN103502271B
(zh)
|
2011-02-28 |
2016-10-26 |
霍夫曼-拉罗奇有限公司 |
抗原结合蛋白
|
MX2013010011A
(es)
|
2011-03-01 |
2014-10-24 |
Amgen Inc |
Agentes de unión biespecífica.
|
CA2812739A1
(en)
|
2011-03-25 |
2012-10-04 |
Glenmark Pharmaceuticals S.A. |
Hetero-dimeric immunoglobulins
|
CN106039306A
(zh)
|
2011-03-30 |
2016-10-26 |
埃博灵克斯股份有限公司 |
使用针对TNFα的单结构域抗体治疗免疫病症的方法
|
CA2827787A1
(en)
|
2011-03-30 |
2012-10-04 |
Boehringer Ingelheim International Gmbh |
Anticoagulant antidotes
|
JP6178785B2
(ja)
|
2011-04-01 |
2017-08-09 |
イェール ユニバーシティーYale University |
細胞浸透性抗dna抗体およびdna修復を阻害するためのその使用
|
UA117218C2
(uk)
|
2011-05-05 |
2018-07-10 |
Мерк Патент Гмбх |
Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
|
EA201891284A1
(ru)
|
2011-05-20 |
2018-11-30 |
Олдербайо Холдингз Ллк |
Композиции антител против cgrp и их применение
|
EA033109B1
(ru)
|
2011-05-20 |
2019-08-30 |
Олдербайо Холдингз Ллк |
Способы ингибирования, профилактики или лечения диареи и/или поддержания соответствующих уровней электролитов и жидкости в толстой кишке субъекта, подвергающегося связанному с диареей состоянию, с помощью антитела против cgrp или фрагмента антитела против cgrp
|
CN108014334B
(zh)
|
2011-05-20 |
2021-11-30 |
H.伦德贝克公司 |
抗cgrp抗体和抗体片段用于在有需要的受试者中预防或抑制畏光或厌光的用途
|
CN106432506A
(zh)
|
2011-05-24 |
2017-02-22 |
泽恩格尼亚股份有限公司 |
多价和单价多特异性复合物及其用途
|
RU2661677C2
(ru)
|
2011-05-27 |
2018-07-18 |
Аблинкс Нв |
Ингибирование резорбции кости с помощью связывающих rank-l пептидов
|
US9580480B2
(en)
|
2011-05-31 |
2017-02-28 |
Massachusetts Institute Of Technology |
Cell-directed synthesis of multifunctional nanopatterns and nanomaterials
|
CN103635487B
(zh)
|
2011-06-17 |
2016-10-12 |
诺沃—诺迪斯克有限公司 |
选择性消除侵蚀性细胞
|
CN104271598A
(zh)
|
2011-06-23 |
2015-01-07 |
埃博灵克斯股份有限公司 |
针对IgE的免疫球蛋白单可变结构域
|
GEP201706667B
(en)
|
2011-06-28 |
2017-05-25 |
Berlin - Chemie Ag |
Antibodies to adp-ribosyl cyclase 2
|
PT2726094T
(pt)
|
2011-06-28 |
2017-02-10 |
Oxford Biotherapeutics Ltd |
Alvo terapêutico e de diagnóstico
|
CN105601748B
(zh)
|
2011-07-01 |
2021-08-27 |
恩格姆生物制药公司 |
用于代谢病症和疾病治疗的组合物、应用和方法
|
MX348738B
(es)
|
2011-07-13 |
2017-06-27 |
Ucb Pharma Sa |
Cepa huesped bacteriana que expresa dsbc recombinante.
|
WO2013016220A1
(en)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
CA2842860A1
(en)
|
2011-07-28 |
2013-01-31 |
Sea Lane Biotechnologies, Llc |
Sur-binding proteins
|
KR20140054177A
(ko)
|
2011-08-05 |
2014-05-08 |
제넨테크, 인크. |
항-폴리유비퀴틴 항체 및 이용 방법
|
CN108178800B
(zh)
|
2011-08-17 |
2022-06-17 |
葛兰素集团有限公司 |
具有降低的与抗药物抗体结合的经修饰的单可变结构域抗体
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
ES2806146T3
(es)
|
2011-09-22 |
2021-02-16 |
Amgen Inc |
Proteínas de unión al antígeno CD27L
|
JP2014530001A
(ja)
*
|
2011-09-23 |
2014-11-17 |
テクノファージ, インベスティガサン エデセンボルビメント エム ビオテクノロジア,エスエー |
抗腫瘍壊死因子−α剤及びその使用
|
EP3311837A1
(en)
|
2011-09-23 |
2018-04-25 |
Ablynx NV |
Prolonged inhibition of interleukin-6 mediated signaling
|
EP2760892A1
(en)
|
2011-09-29 |
2014-08-06 |
Apo-T B.V. |
Multi-specific binding molecules targeting aberrant cells
|
US9127056B2
(en)
|
2011-10-17 |
2015-09-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monospecific and bispecific human monoclonal antibodies targeting insulin-like growth factor II (IGF-II)
|
US20130122005A1
(en)
|
2011-10-27 |
2013-05-16 |
Paul Adam |
Anticancer combination therapy
|
CA2853230C
(en)
|
2011-10-31 |
2021-11-23 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule having regulated conjugation between heavy-chain and light-chain
|
AU2012332587B2
(en)
|
2011-11-01 |
2017-02-23 |
Bionomics, Inc. |
Antibodies and methods of treating cancer
|
ES2697674T3
(es)
|
2011-11-01 |
2019-01-25 |
Bionomics Inc |
Procedimientos para bloquear el crecimiento de células madre cancerosas
|
ES2666856T3
(es)
|
2011-11-04 |
2018-05-08 |
Novartis Ag |
Proteína 6 relacionada con lipoproteínas de baja densidad (LRP6) - constructos extensores de la vida media
|
SI2776466T1
(sl)
|
2011-11-11 |
2017-12-29 |
Ucb Biopharma Sprl |
Protitelesa, ki se vežejo na albumin in njihovi vezavni fragmenti
|
AU2012346448B2
(en)
|
2011-12-02 |
2017-09-14 |
Armagen, Inc. |
Methods and compositions for increasing arylsulfatase A activity in the CNS
|
BR112014013412A8
(pt)
|
2011-12-05 |
2021-06-08 |
Novartis Ag |
anticorpos para o receptor 3 do fator de crescimento epidérmico (her3), e seus usos
|
AU2012349736A1
(en)
|
2011-12-05 |
2014-06-26 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (HER3) directed to domain II of HER3
|
SI2793567T1
(sl)
|
2011-12-20 |
2019-05-31 |
Regeneron Pharmaceuticals, Inc. |
Humanizirane lahkoverižne miši
|
EP3446707A1
(en)
|
2011-12-22 |
2019-02-27 |
i2 Pharmaceuticals, Inc. |
Surrogate binding proteins
|
TWI593705B
(zh)
|
2011-12-28 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Humanized anti-epiregulin antibody and cancer therapeutic agent containing the antibody as an active ingredient
|
EP2802356A1
(en)
|
2012-01-13 |
2014-11-19 |
Apo-T B.V. |
Aberrant cell-restricted immunoglobulins provided with a toxic moiety
|
RU2693264C2
(ru)
*
|
2012-02-03 |
2019-07-01 |
Ф.Хоффман-Ля Рош Аг |
Молекулы биспецифических антител и т-клетки, трансфецированные антигеном, и их применение в медицине
|
MX2014009565A
(es)
*
|
2012-02-10 |
2014-11-10 |
Genentech Inc |
Anticuerpos monocatenarios y otros heteromultimeros.
|
GB201203051D0
(en)
*
|
2012-02-22 |
2012-04-04 |
Ucb Pharma Sa |
Biological products
|
GB201203071D0
(en)
*
|
2012-02-22 |
2012-04-04 |
Ucb Pharma Sa |
Biological products
|
KR101505157B1
(ko)
*
|
2012-05-08 |
2015-03-24 |
주식회사 종근당 |
항―ErbB2 항체 변이체
|
US9328174B2
(en)
|
2012-05-09 |
2016-05-03 |
Novartis Ag |
Chemokine receptor binding polypeptides
|
GB201208367D0
(en)
|
2012-05-14 |
2012-06-27 |
Ucb Pharma Sa |
Biological product
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
KR101718200B1
(ko)
*
|
2012-05-21 |
2017-03-21 |
제넨테크, 인크. |
항-Ly6E 항체 및 면역접합체 및 사용 방법
|
RU2014149681A
(ru)
*
|
2012-05-24 |
2016-07-20 |
Ф. Хоффманн-Ля Рош Аг |
Антитела с множественной специфичностью
|
US11339208B1
(en)
|
2012-05-31 |
2022-05-24 |
United States Of America As Represented By The Secretary Of The Air Force |
Camelidae single-domain antibodies against Yersinia pestis and methods of use
|
BR112014032193A2
(pt)
|
2012-06-27 |
2017-06-27 |
Hoffmann La Roche |
métodos de produção de anticorpos biespecíficos e de determinação de combinação, anticorpo biespecífico, formulação e uso de anticorpo biespecífico
|
WO2014001325A1
(en)
|
2012-06-27 |
2014-01-03 |
F. Hoffmann-La Roche Ag |
Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof
|
GB201213652D0
(en)
|
2012-08-01 |
2012-09-12 |
Oxford Biotherapeutics Ltd |
Therapeutic and diagnostic target
|
WO2014022540A1
(en)
*
|
2012-08-02 |
2014-02-06 |
Regeneron Pharmaceuticals, Inc. |
Multivalent antigen-binding proteins
|
WO2014029752A1
(en)
|
2012-08-22 |
2014-02-27 |
Glaxo Group Limited |
Anti lrp6 antibodies
|
RS57120B1
(sr)
|
2012-10-03 |
2018-06-29 |
Chiome Bioscience Inc |
Anti-humano dlk-1 antitelo koje ima in vivo aktivnost protiv tumora
|
KR20210111353A
(ko)
|
2012-11-01 |
2021-09-10 |
애브비 인코포레이티드 |
항-vegf/dll4 이원 가변 도메인 면역글로불린 및 이의 용도
|
WO2014085365A2
(en)
|
2012-11-28 |
2014-06-05 |
Ngm Biopharmaceuticals, Inc. |
Compositions and methods for treatment of metabolic disorders and diseases
|
PT2925782T
(pt)
|
2012-12-03 |
2020-04-22 |
Novimmune Sa |
Anticorpos anti-cd47 e métodos de utilização destes
|
WO2014086496A1
(en)
*
|
2012-12-05 |
2014-06-12 |
Dutalys Gmbh |
Dual targeting
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
CN105008548B
(zh)
|
2012-12-27 |
2020-11-27 |
恩格姆生物制药公司 |
用于调节胆汁酸体内稳态以及治疗胆汁酸紊乱和疾病的方法
|
WO2014111550A1
(en)
|
2013-01-17 |
2014-07-24 |
Glaxosmithkline Intellectual Property Development Limited |
Modified anti-serum albumin binding proteins
|
ES2728936T3
(es)
|
2013-01-25 |
2019-10-29 |
Amgen Inc |
Anticuerpos dirigidos contra CDH19 para melanoma
|
JO3519B1
(ar)
*
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
WO2014120916A1
(en)
|
2013-02-01 |
2014-08-07 |
Bristol-Myers Squibb Company |
Pegylated domain antibodies monovalent for cd28 binding and methods of use
|
GB201302447D0
(en)
|
2013-02-12 |
2013-03-27 |
Oxford Biotherapeutics Ltd |
Therapeutic and diagnostic target
|
DK2962100T3
(da)
|
2013-02-28 |
2021-11-01 |
Caprion Proteomics Inc |
Tuberkulosebiomarkører og anvendelser deraf
|
US20140255413A1
(en)
|
2013-03-07 |
2014-09-11 |
Boehringer Ingelheim International Gmbh |
Combination therapy for neoplasia treatment
|
WO2014159239A2
(en)
|
2013-03-14 |
2014-10-02 |
Novartis Ag |
Antibodies against notch 3
|
US10993420B2
(en)
|
2013-03-15 |
2021-05-04 |
Erasmus University Medical Center |
Production of heavy chain only antibodies in transgenic mammals
|
CN105530959B
(zh)
*
|
2013-03-15 |
2021-09-17 |
纪念斯隆-凯特琳癌症中心 |
多聚化技术
|
AR095374A1
(es)
*
|
2013-03-15 |
2015-10-14 |
Amgen Res (Munich) Gmbh |
Moléculas de unión para bcma y cd3
|
EP2970484B2
(en)
*
|
2013-03-15 |
2022-09-21 |
Amgen Inc. |
Heterodimeric bispecific antibodies
|
EP2968541A4
(en)
|
2013-03-15 |
2017-02-08 |
Zyngenia, Inc. |
Multivalent and monovalent multispecific complexes and their uses
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
SG10201708048XA
(en)
|
2013-03-18 |
2017-10-30 |
Biocerox Prod Bv |
Humanized anti-cd134 (ox40) antibodies and uses thereof
|
CN110511279B
(zh)
|
2013-05-30 |
2024-03-29 |
基尼克萨制药有限公司 |
制瘤素m受体抗原结合蛋白
|
WO2014198748A1
(en)
*
|
2013-06-11 |
2014-12-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-her2 single domain antibodies, polypeptides comprising thereof and their use for treating cancer
|
EP4067383A1
(en)
*
|
2013-07-25 |
2022-10-05 |
Cytomx Therapeutics Inc. |
Multispecific antibodies, multispecific activatable antibodies and methods of using the same
|
TWI671317B
(zh)
|
2013-08-02 |
2019-09-11 |
輝瑞大藥廠 |
抗cxcr4抗體及抗體-藥物結合物
|
UA117493C2
(uk)
*
|
2013-08-30 |
2018-08-10 |
Апрілбіо Ко., Лтд |
Гібридна конструкція, що включає антигенсполучний фрагмент, специфічний до сироваткового альбуміну, й ефекторний компонент, та способи її одержання
|
WO2015050959A1
(en)
|
2013-10-01 |
2015-04-09 |
Yale University |
Anti-kit antibodies and methods of use thereof
|
CN105848722B
(zh)
|
2013-10-02 |
2021-09-03 |
免疫医疗有限责任公司 |
中和抗甲型流感抗体及其用途
|
JP6422956B2
(ja)
|
2013-10-11 |
2018-11-14 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
多重特異性ドメイン交換共通可変軽鎖抗体
|
KR102178323B1
(ko)
*
|
2013-11-29 |
2020-11-13 |
삼성전자주식회사 |
항 c-Met/항 Ang2 이중 특이 항체
|
JP7325166B2
(ja)
*
|
2013-12-20 |
2023-08-14 |
ジェネンテック, インコーポレイテッド |
二重特異性抗体
|
WO2015100459A2
(en)
|
2013-12-27 |
2015-07-02 |
Merrimack Pharmaceuticals, Inc. |
Biomarker profiles for predicting outcomes of cancer therapy with erbb3 inhibitors and/or chemotherapies
|
RU2019119857A
(ru)
|
2014-02-20 |
2019-07-12 |
Аллерган, Инк. |
Антитела к компоненту комплемента c5
|
WO2015130826A1
(en)
|
2014-02-27 |
2015-09-03 |
Allergan, Inc. |
COMPLEMENT FACTOR Bb ANTIBODIES
|
JP6568099B2
(ja)
|
2014-03-21 |
2019-08-28 |
テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーTeva Pharmaceuticals International GmbH |
カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体及びその使用方法
|
CN106255410B
(zh)
|
2014-03-21 |
2020-01-10 |
瑞泽恩制药公司 |
产生单结构域结合蛋白的非人动物
|
SG10201808083VA
(en)
|
2014-03-21 |
2018-10-30 |
Regeneron Pharma |
Vl antigen binding proteins exhibiting distinct binding characteristics
|
US10556945B2
(en)
|
2014-03-21 |
2020-02-11 |
Teva Pharmaceuticals International Gmbh |
Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
|
WO2015153916A1
(en)
|
2014-04-04 |
2015-10-08 |
Bionomics, Inc. |
Humanized antibodies that bind lgr5
|
DK3129470T3
(da)
*
|
2014-04-07 |
2021-07-05 |
Novartis Ag |
Behandling af cancer ved anvendelse af anti-CD19-kimær antigenreceptor
|
NZ724710A
(en)
|
2014-04-07 |
2024-02-23 |
Chugai Pharmaceutical Co Ltd |
Immunoactivating antigen-binding molecule
|
TW201623333A
(zh)
|
2014-05-13 |
2016-07-01 |
Chugai Pharmaceutical Co Ltd |
對具有免疫抑制機能之細胞的t細胞重定向抗原結合分子
|
JP7325928B2
(ja)
|
2014-05-16 |
2023-08-15 |
アブリンクス エン.ヴェー. |
改善された免疫グロブリン可変ドメイン
|
NL2013661B1
(en)
|
2014-10-21 |
2016-10-05 |
Ablynx Nv |
KV1.3 Binding immunoglobulins.
|
US10238742B2
(en)
*
|
2014-06-25 |
2019-03-26 |
Yale University |
Cell penetrating nucleolytic antibody based cancer therapy
|
CN107108738A
(zh)
|
2014-07-25 |
2017-08-29 |
西托姆克斯治疗公司 |
抗cd3抗体、可活化抗cd3抗体、多特异性抗cd3抗体、多特异性可活化抗cd3抗体及其使用方法
|
JP6749312B2
(ja)
|
2014-07-31 |
2020-09-02 |
アムゲン リサーチ (ミュンヘン) ゲーエムベーハーAMGEN Research(Munich)GmbH |
最適化された種間特異的二重特異性単鎖抗体コンストラクト
|
AR101669A1
(es)
*
|
2014-07-31 |
2017-01-04 |
Amgen Res (Munich) Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
KR102259232B1
(ko)
*
|
2014-08-25 |
2021-05-31 |
삼성전자주식회사 |
항 c-Met/항 Ang2 이중 특이 항체
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
IL251834B2
(en)
|
2014-10-23 |
2023-09-01 |
Ngm Biopharmaceuticals Inc |
Pharmaceutical compositions containing peptide variants and methods of using them
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
CN107074941A
(zh)
|
2014-11-10 |
2017-08-18 |
豪夫迈·罗氏有限公司 |
双特异性抗体和用于眼科学的方法
|
BR112017009817A2
(pt)
|
2014-11-10 |
2018-02-14 |
Hoffmann La Roche |
anticorpos anti-il-1beta e métodos de utilização
|
CA2963606A1
(en)
*
|
2014-11-10 |
2016-05-19 |
F.Hoffmann-La Roche Ag |
Anti-ang2 antibodies and methods of use
|
JP6721590B2
(ja)
|
2014-12-03 |
2020-07-15 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
多重特異性抗体
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
WO2016097313A1
(en)
|
2014-12-19 |
2016-06-23 |
Ablynx N.V. |
Cysteine linked nanobody dimers
|
US10538589B2
(en)
|
2015-01-14 |
2020-01-21 |
Armagen Inc. |
Methods and compositions for increasing N-acetylglucosaminidase (NAGLU) activity in the CNS using a fusion antibody comprising an anti-human insulin receptor antibody and NAGLU
|
AU2016214317B2
(en)
*
|
2015-02-05 |
2022-01-13 |
Ablynx N.V. |
Nanobody dimers linked via C-terminally engineered cysteins
|
CA2979702A1
(en)
|
2015-03-19 |
2016-09-22 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals that select for light chain variable regions that bind antigen
|
KR20170134642A
(ko)
|
2015-04-08 |
2017-12-06 |
노파르티스 아게 |
Cd20 요법, cd22 요법, 및 cd19 키메라 항원 수용체 (car) - 발현 세포와의 조합 요법
|
EP3297672B1
(en)
|
2015-05-21 |
2021-09-01 |
Harpoon Therapeutics, Inc. |
Trispecific binding proteins and methods of use
|
US10184006B2
(en)
|
2015-06-04 |
2019-01-22 |
Merrimack Pharmaceuticals, Inc. |
Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
CA2999138C
(en)
|
2015-09-21 |
2024-05-21 |
Aptevo Research And Development Llc |
Cd3 binding polypeptides
|
CA3082794A1
(en)
|
2015-11-09 |
2017-05-18 |
Ngm Biopharmaceuticals Inc. |
Methods for treatment of bile acid-related disorders
|
JP6931329B2
(ja)
|
2015-11-18 |
2021-09-01 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するt細胞リダイレクト抗原結合分子を用いた併用療法
|
US11649293B2
(en)
|
2015-11-18 |
2023-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Method for enhancing humoral immune response
|
KR20180091918A
(ko)
|
2015-12-28 |
2018-08-16 |
추가이 세이야쿠 가부시키가이샤 |
Fc 영역 함유 폴리펩타이드의 정제를 효율화하기 위한 방법
|
MX2018010988A
(es)
|
2016-03-14 |
2019-01-21 |
Chugai Pharmaceutical Co Ltd |
Farmaco terapeutico que induce lesion celular para usarse en terapia de cancer.
|
WO2017161414A1
(en)
|
2016-03-22 |
2017-09-28 |
Bionomics Limited |
Administration of an anti-lgr5 monoclonal antibody
|
KR20180131557A
(ko)
|
2016-04-05 |
2018-12-10 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
면역요법에서의 tgf베타의 억제
|
LT3458478T
(lt)
|
2016-05-18 |
2021-02-10 |
Boehringer Ingelheim International Gmbh |
Antikūnai prieš pd-1 ir lag-3, skirti vėžio gydymui
|
KR102365977B1
(ko)
|
2016-05-20 |
2022-02-22 |
하푼 테라퓨틱스, 인크. |
단일 쇄 가변 단편 cd3 결합 단백질
|
JP7101621B2
(ja)
|
2016-05-20 |
2022-07-15 |
ハープーン セラピューティクス,インク. |
単一ドメイン血清アルブミン結合タンパク質
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
EP3463430A4
(en)
|
2016-06-03 |
2020-02-12 |
Janssen Biotech, Inc. |
SERUM ALBUMIN BINDING FIBRONECTIN TYPE III DOMAINS
|
WO2017218825A1
(en)
|
2016-06-15 |
2017-12-21 |
Yale University |
Antibody-mediated autocatalytic, targeted delivery of nanocarriers to tumors
|
WO2018007442A1
(en)
|
2016-07-06 |
2018-01-11 |
Ablynx N.V. |
Treatment of il-6r related diseases
|
WO2018020000A1
(en)
|
2016-07-29 |
2018-02-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies targeting tumor associated macrophages and uses thereof
|
WO2018029182A1
(en)
|
2016-08-08 |
2018-02-15 |
Ablynx N.V. |
Il-6r single variable domain antibodies for treatment of il-6r related diseases
|
KR20220031944A
(ko)
|
2016-09-23 |
2022-03-14 |
테바 파마슈티컬스 인터내셔널 게엠베하 |
불응성 편두통의 치료
|
US10525083B2
(en)
|
2016-10-07 |
2020-01-07 |
Novartis Ag |
Nucleic acid molecules encoding chimeric antigen receptors comprising a CD20 binding domain
|
WO2018091606A1
(en)
|
2016-11-16 |
2018-05-24 |
Ablynx Nv |
T cell recruiting polypeptides capable of binding cd123 and tcr alpha/beta
|
EP3544997A4
(en)
|
2016-11-23 |
2020-07-01 |
Harpoon Therapeutics, Inc. |
PROSTATE SPECIFIC MEMBRANE ANTIGEN BINDING PROTEIN
|
BR112019010602A2
(pt)
|
2016-11-23 |
2019-12-17 |
Harpoon Therapeutics Inc |
proteínas trispecíficas para psma e métodos de uso
|
CN110049997B
(zh)
|
2016-12-07 |
2023-09-22 |
埃博灵克斯股份有限公司 |
改进的血清白蛋白结合免疫球蛋白单可变结构域
|
EP3360898A1
(en)
|
2017-02-14 |
2018-08-15 |
Boehringer Ingelheim International GmbH |
Bispecific anti-tnf-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer
|
WO2018129029A1
(en)
|
2017-01-04 |
2018-07-12 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
BR112019014600A2
(pt)
|
2017-01-17 |
2020-02-18 |
Ablynx N.V. |
Ligantes de albumina sérica melhorados
|
US11414481B2
(en)
|
2017-01-17 |
2022-08-16 |
Ablynx N.V. |
Serum albumin binders
|
EP3576790A4
(en)
|
2017-02-01 |
2020-12-23 |
Yale University |
TREATMENT OF DIURETIC RESISTANCE
|
US11535668B2
(en)
|
2017-02-28 |
2022-12-27 |
Harpoon Therapeutics, Inc. |
Inducible monovalent antigen binding protein
|
CN110392697A
(zh)
|
2017-03-02 |
2019-10-29 |
国家医疗保健研究所 |
对nectin-4具有特异性的抗体及其用途
|
JP7090347B2
(ja)
|
2017-05-12 |
2022-06-24 |
ハープーン セラピューティクス,インク. |
メソテリン結合タンパク質
|
EP3621648A4
(en)
|
2017-05-12 |
2021-01-20 |
Harpoon Therapeutics, Inc. |
TRISPECIFIC PROTEINS MSLN AND METHOD OF USE
|
AU2018276409A1
(en)
*
|
2017-05-31 |
2019-10-31 |
Boehringer Ingelheim International Gmbh |
Polypeptides antagonizing Wnt signaling in tumor cells
|
IL253015B2
(en)
|
2017-06-18 |
2023-07-01 |
Israel Aerospace Ind Ltd |
System and method for refueling aerial vehicles
|
IL253407B
(en)
|
2017-07-10 |
2020-08-31 |
Israel Aerospace Ind Ltd |
refueling station
|
WO2019020480A1
(en)
|
2017-07-24 |
2019-01-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
ANTIBODIES AND PEPTIDES FOR TREATING HCMV RELATED DISEASES
|
WO2019036855A1
(en)
|
2017-08-21 |
2019-02-28 |
Adagene Inc. |
ANTI-CD137 MOLECULES AND THEIR USE
|
MA50352A
(fr)
|
2017-10-10 |
2020-08-19 |
Numab Therapeutics AG |
Anticorps multispécifiques
|
EP3470426A1
(en)
|
2017-10-10 |
2019-04-17 |
Numab Therapeutics AG |
Multispecific antibody
|
AU2018346955A1
(en)
|
2017-10-13 |
2020-04-30 |
Harpoon Therapeutics, Inc. |
B cell maturation antigen binding proteins
|
CN111630070A
(zh)
|
2017-10-13 |
2020-09-04 |
哈普恩治疗公司 |
三特异性蛋白质及使用方法
|
KR20200064096A
(ko)
|
2017-10-14 |
2020-06-05 |
싸이톰스 테라퓨틱스, 인크. |
항체, 활성화 가능한 항체, 이중특이적 항체 및 이중특이적 활성화 가능한 항체 및 이들의 사용 방법
|
CA3087699A1
(en)
|
2018-01-05 |
2019-07-11 |
Corvidia Therapeutics, Inc. |
Methods for treating il-6 mediated inflammation without immunosuppression
|
WO2019148444A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Anti-ctla4 antibodies and methods of making and using the same
|
WO2019148445A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Precision/context-dependent activatable antibodies, and methods of making and using the same
|
EP3569618A1
(en)
|
2018-05-19 |
2019-11-20 |
Boehringer Ingelheim International GmbH |
Antagonizing cd73 antibody
|
DE202019005887U1
(de)
|
2018-07-03 |
2023-06-14 |
Marengo Therapeutics, Inc. |
Anti-TCR-Antikörpermoleküle und Verwendungen davon
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
US20220047701A1
(en)
|
2018-09-10 |
2022-02-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combination of her2/neu antibody with heme for treating cancer
|
JP7425049B2
(ja)
|
2018-09-25 |
2024-01-30 |
ハープーン セラピューティクス,インク. |
Dll3結合タンパク質および使用方法
|
CA3117520A1
(en)
|
2018-10-25 |
2020-04-30 |
Polpharma Biologics Utrecht B.V. |
Anti-human cd89 antibodies and uses thereof
|
GB201818477D0
(en)
|
2018-11-13 |
2018-12-26 |
Emstopa Ltd |
Tissue plasminogen activator antibodies and method of use thereof
|
WO2020114615A1
(en)
*
|
2018-12-07 |
2020-06-11 |
Baxalta GmbH |
Bispecific antibodies binding factor ixa and factor x
|
WO2020115283A1
(en)
*
|
2018-12-07 |
2020-06-11 |
Baxalta GmbH |
Bispecific antibodies binding factor ixa and factor x
|
JP2022516956A
(ja)
|
2019-01-08 |
2022-03-03 |
ハー・ルンドベック・アクチエゼルスカベット |
抗cgrp抗体を用いた頭痛の急性治療及び迅速治療
|
US20220177558A1
(en)
|
2019-03-25 |
2022-06-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Treatment of taupathy disorders by targeting new tau species
|
WO2020198731A2
(en)
|
2019-03-28 |
2020-10-01 |
Danisco Us Inc |
Engineered antibodies
|
WO2021058729A1
(en)
|
2019-09-27 |
2021-04-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-müllerian inhibiting substance type i receptor antibodies and uses thereof
|
EP4034560A1
(en)
|
2019-09-27 |
2022-08-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-müllerian inhibiting substance antibodies and uses thereof
|
EP3816185A1
(en)
|
2019-11-04 |
2021-05-05 |
Numab Therapeutics AG |
Multispecific antibody directed against pd-l1 and a tumor-associated antigen
|
WO2021116119A1
(en)
|
2019-12-09 |
2021-06-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies having specificity to her4 and uses thereof
|
GB201919061D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Multi-specific antibody
|
US20230052646A1
(en)
|
2019-12-24 |
2023-02-16 |
Jjp Biologics Sp. Z O.O. |
Anti-Human Hvem (TNFRSF14) Antibodies And Uses Thereof
|
CN113248611A
(zh)
|
2020-02-13 |
2021-08-13 |
湖南华康恒健生物技术有限公司 |
抗bcma抗体、其药物组合物及应用
|
JP2023527609A
(ja)
|
2020-02-21 |
2023-06-30 |
ハープーン セラピューティクス,インク. |
Flt3結合タンパク質および使用方法
|
WO2021205183A1
(en)
|
2020-04-09 |
2021-10-14 |
Autolus Limited |
Polypeptide
|
AU2021259052A1
(en)
|
2020-04-21 |
2022-12-01 |
Jjp Biologics Sp. Z O.O. |
Humanized anti-human CD89 antibodies and uses thereof
|
US20230181753A1
(en)
|
2020-05-12 |
2023-06-15 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
New method to treat cutaneous t-cell lymphomas and tfh derived lymphomas
|
GB202007441D0
(en)
|
2020-05-19 |
2020-07-01 |
Autolus Ltd |
Polypeptide
|
BR112022021447A2
(pt)
|
2020-05-19 |
2022-12-13 |
Boehringer Ingelheim Int |
Moléculas de ligação para o tratamento de câncer
|
EP3915580A1
(en)
|
2020-05-29 |
2021-12-01 |
Numab Therapeutics AG |
Multispecific antibody
|
CN114106173A
(zh)
|
2020-08-26 |
2022-03-01 |
上海泰槿生物技术有限公司 |
抗ox40抗体、其药物组合物及应用
|
US20230312689A1
(en)
|
2020-08-26 |
2023-10-05 |
National University Corporation Kumamoto University |
Human antibody or antigen-binding fragment thereof against coronavirus spike protein
|
EP4232474A1
(en)
|
2020-10-21 |
2023-08-30 |
Boehringer Ingelheim International GmbH |
Bispecific anti-vegf and anti-trkb binding molecules for the treatment of eye diseases
|
EP3988568A1
(en)
|
2020-10-21 |
2022-04-27 |
Numab Therapeutics AG |
Combination treatment
|
WO2022098745A1
(en)
|
2020-11-03 |
2022-05-12 |
Indi Molecular, Inc. |
Compositions, delivery systems, and methods useful in tumor therapy
|
WO2022098743A1
(en)
|
2020-11-03 |
2022-05-12 |
Indi Molecular, Inc. |
Compositions, imaging, and therapeutic methods targeting folate receptor 1 (folr1)
|
JP2023551981A
(ja)
|
2020-12-07 |
2023-12-13 |
ユーシービー バイオファルマ エスアールエル |
多重特異性抗体及び抗体の組み合わせ
|
AU2022215847A1
(en)
|
2021-02-02 |
2023-08-10 |
Numab Therapeutics AG |
Multispecific antibodies having specificity for ror1 and cd3
|
AU2022224636A1
(en)
|
2021-02-19 |
2023-09-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies that neutralize sars-cov-2
|
CN117597359A
(zh)
|
2021-04-08 |
2024-02-23 |
马伦戈治疗公司 |
与tcr结合的多功能分子及其用途
|
TW202317625A
(zh)
|
2021-06-17 |
2023-05-01 |
德商百靈佳殷格翰國際股份有限公司 |
新穎三特異性結合分子
|
EP4183800A1
(en)
|
2021-11-19 |
2023-05-24 |
Medizinische Hochschule Hannover |
Novel sars-cov-2 neutralizing antibodies
|
WO2023175171A1
(en)
|
2022-03-18 |
2023-09-21 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Bk polyomavirus antibodies and uses thereof
|
WO2023196932A2
(en)
*
|
2022-04-06 |
2023-10-12 |
The Regents Of The University Of California |
Isolating active t-cell cars from bulk transduced human t-cells
|
US20240052065A1
(en)
|
2022-07-15 |
2024-02-15 |
Boehringer Ingelheim International Gmbh |
Binding molecules for the treatment of cancer
|
WO2024038095A1
(en)
|
2022-08-16 |
2024-02-22 |
Iome Bio |
NOVEL ANTI-RGMb ANTIBODIES
|
WO2024052503A1
(en)
|
2022-09-08 |
2024-03-14 |
Institut National de la Santé et de la Recherche Médicale |
Antibodies having specificity to ltbp2 and uses thereof
|
WO2024056668A1
(en)
|
2022-09-12 |
2024-03-21 |
Institut National de la Santé et de la Recherche Médicale |
New anti-itgb8 antibodies and its uses thereof
|
WO2024083843A1
(en)
|
2022-10-18 |
2024-04-25 |
Confo Therapeutics N.V. |
Amino acid sequences directed against the melanocortin 4 receptor and polypeptides comprising the same for the treatment of mc4r-related diseases and disorders
|