DK2447719T3 - Proteiner - Google Patents

Proteiner Download PDF

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Publication number
DK2447719T3
DK2447719T3 DK12152158T DK12152158T DK2447719T3 DK 2447719 T3 DK2447719 T3 DK 2447719T3 DK 12152158 T DK12152158 T DK 12152158T DK 12152158 T DK12152158 T DK 12152158T DK 2447719 T3 DK2447719 T3 DK 2447719T3
Authority
DK
Denmark
Prior art keywords
cancer
sequences
column
applications
identified
Prior art date
Application number
DK12152158T
Other languages
English (en)
Inventor
Christian Rohlff
Alasdair Stamps
Original Assignee
Oxford Biotherapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2007/055537 external-priority patent/WO2007141280A2/en
Priority claimed from PCT/GB2008/050124 external-priority patent/WO2008104803A2/en
Application filed by Oxford Biotherapeutics Ltd filed Critical Oxford Biotherapeutics Ltd
Application granted granted Critical
Publication of DK2447719T3 publication Critical patent/DK2447719T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (3)

1. Isoleret monoklonalt antistof, der er i stand til immun-specifik binding til CUB-domæne-holdigt protein 1 eller et fragment eller derivat deraf, der omfatter antigenbindingsdomænet, til anvendelse til behandling af lungecancer, hvor antistoffet eller fragmentet eller derivatet deraf er konjugeret til en cytotoksisk del eller en lægemiddeldel.
2. Isoleret monoklonalt antistof til anvendelse ifølge krav 1, hvor lungecanceren er en småcellet lungecancer.
3. Isoleret monoklonalt antistof til anvendelse ifølge krav 1 eller krav 2, hvor: (A) antistoffet er udvalgt fra gruppen bestående et kimærisk antistof, et humant antistof, et humaniseret antistof, et enkeltkædet antistof, et bispecifikt antistof og et ikke-fucosyleret antistof; (B) fragmentet er et domæneantistof.
DK12152158T 2007-02-26 2008-02-26 Proteiner DK2447719T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90350907P 2007-02-26 2007-02-26
US90351007P 2007-02-26 2007-02-26
PCT/EP2007/055537 WO2007141280A2 (en) 2006-06-06 2007-06-05 Proteins
PCT/GB2008/050124 WO2008104803A2 (en) 2007-02-26 2008-02-25 Proteins
EP08709645A EP2121745A2 (en) 2007-02-26 2008-02-26 Proteins

Publications (1)

Publication Number Publication Date
DK2447719T3 true DK2447719T3 (da) 2016-10-10

Family

ID=41213476

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12152158T DK2447719T3 (da) 2007-02-26 2008-02-26 Proteiner

Country Status (2)

Country Link
EP (3) EP3118221B1 (da)
DK (1) DK2447719T3 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110234348A (zh) 2016-12-16 2019-09-13 蓝鳍生物医药公司 抗-含cub结构域蛋白1(cdcp1)抗体、抗体药物缀合物及其使用方法
EP3629021A1 (en) * 2018-09-26 2020-04-01 Euroimmun Medizinische Labordiagnostika AG Diagnosis of a neuroautoimmune disease
CN117347621B (zh) * 2023-08-25 2024-03-12 广东省农业科学院农业生物基因研究中心 一种用蛋白模拟抗原-纳米抗体检测黄曲霉毒素b1的方法

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Also Published As

Publication number Publication date
EP3118221B1 (en) 2019-08-21
EP2121745A2 (en) 2009-11-25
EP2447719B1 (en) 2016-08-24
EP2447719A1 (en) 2012-05-02
EP3118221A1 (en) 2017-01-18

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