US20030206887A1
(en)
*
|
1992-05-14 |
2003-11-06 |
David Morrissey |
RNA interference mediated inhibition of hepatitis B virus (HBV) using short interfering nucleic acid (siNA)
|
US20030216335A1
(en)
*
|
2001-11-30 |
2003-11-20 |
Jennifer Lockridge |
Method and reagent for the modulation of female reproductive diseases and conditions
|
US9096636B2
(en)
|
1996-06-06 |
2015-08-04 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
NZ547283A
(en)
|
1998-03-20 |
2008-06-30 |
Commw Scient Ind Res Org |
Control of gene expression
|
AUPP249298A0
(en)
|
1998-03-20 |
1998-04-23 |
Ag-Gene Australia Limited |
Synthetic genes and genetic constructs comprising same I
|
EP1147204A1
(en)
*
|
1999-01-28 |
2001-10-24 |
Medical College Of Georgia Research Institute, Inc. |
Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna
|
DE19956568A1
(de)
|
1999-01-30 |
2000-08-17 |
Roland Kreutzer |
Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
|
US7601494B2
(en)
|
1999-03-17 |
2009-10-13 |
The University Of North Carolina At Chapel Hill |
Method of screening candidate compounds for susceptibility to biliary excretion
|
US20070021979A1
(en)
*
|
1999-04-16 |
2007-01-25 |
Cosentino Daniel L |
Multiuser wellness parameter monitoring system
|
WO2000063364A2
(en)
*
|
1999-04-21 |
2000-10-26 |
American Home Products Corporation |
Methods and compositions for inhibiting the function of polynucleotide sequences
|
US6423885B1
(en)
|
1999-08-13 |
2002-07-23 |
Commonwealth Scientific And Industrial Research Organization (Csiro) |
Methods for obtaining modified phenotypes in plant cells
|
US7067722B2
(en)
|
1999-08-26 |
2006-06-27 |
Monsanto Technology Llc |
Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
|
JP4744049B2
(ja)
|
1999-08-26 |
2011-08-10 |
モンサント・カンパニー |
改質したポリ不飽和脂肪酸を有する植物
|
US7531718B2
(en)
|
1999-08-26 |
2009-05-12 |
Monsanto Technology, L.L.C. |
Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
|
GB9925459D0
(en)
*
|
1999-10-27 |
1999-12-29 |
Plant Bioscience Ltd |
Gene silencing
|
GB9927444D0
(en)
*
|
1999-11-19 |
2000-01-19 |
Cancer Res Campaign Tech |
Inhibiting gene expression
|
US7829693B2
(en)
|
1999-11-24 |
2010-11-09 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a target gene
|
DE10100586C1
(de)
|
2001-01-09 |
2002-04-11 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines Ziegens
|
DE10160151A1
(de)
*
|
2001-01-09 |
2003-06-26 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines vorgegebenen Zielgens
|
WO2003070918A2
(en)
|
2002-02-20 |
2003-08-28 |
Ribozyme Pharmaceuticals, Incorporated |
Rna interference by modified short interfering nucleic acid
|
WO2005041859A2
(en)
|
2003-04-30 |
2005-05-12 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery.
|
US7491805B2
(en)
|
2001-05-18 |
2009-02-17 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
US7833992B2
(en)
|
2001-05-18 |
2010-11-16 |
Merck Sharpe & Dohme |
Conjugates and compositions for cellular delivery
|
WO2002081628A2
(en)
|
2001-04-05 |
2002-10-17 |
Ribozyme Pharmaceuticals, Incorporated |
Modulation of gene expression associated with inflammation proliferation and neurite outgrowth, using nucleic acid based technologies
|
US8202979B2
(en)
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
US8273866B2
(en)
|
2002-02-20 |
2012-09-25 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA)
|
US8202846B2
(en)
|
2000-03-16 |
2012-06-19 |
Cold Spring Harbor Laboratory |
Methods and compositions for RNA interference
|
JP2003526367A
(ja)
|
2000-03-16 |
2003-09-09 |
ジェネティカ インコーポレイテッド |
Rna干渉の方法とrna干渉組成物
|
AU2001249622B2
(en)
*
|
2000-03-30 |
2007-06-07 |
Massachusetts Institute Of Technology |
RNA sequence-specific mediators of RNA interference
|
PT2361981E
(pt)
*
|
2000-03-30 |
2013-06-12 |
Max Planck Gesellschaft |
Mediadores de interferência por rna específicos de sequência de rna
|
US20080032942A1
(en)
|
2000-08-30 |
2008-02-07 |
Mcswiggen James |
RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
|
US20030190635A1
(en)
*
|
2002-02-20 |
2003-10-09 |
Mcswiggen James A. |
RNA interference mediated treatment of Alzheimer's disease using short interfering RNA
|
AU2001297906B2
(en)
*
|
2000-10-31 |
2007-07-19 |
Commonwealth Scientific And Industrial Research Organisation |
Method and means for producing barley yellow dwarf virus resistant cereal plants
|
US20020173478A1
(en)
*
|
2000-11-14 |
2002-11-21 |
The Trustees Of The University Of Pennsylvania |
Post-transcriptional gene silencing by RNAi in mammalian cells
|
WO2002044321A2
(en)
|
2000-12-01 |
2002-06-06 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Rna interference mediating small rna molecules
|
US7767802B2
(en)
|
2001-01-09 |
2010-08-03 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of anti-apoptotic genes
|
US8546143B2
(en)
|
2001-01-09 |
2013-10-01 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a target gene
|
US7423142B2
(en)
|
2001-01-09 |
2008-09-09 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of anti-apoptotic genes
|
DE10100587C1
(de)
*
|
2001-01-09 |
2002-11-21 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines Zielgens
|
WO2003035869A1
(de)
*
|
2001-10-26 |
2003-05-01 |
Ribopharma Ag |
Verwendung einer doppelsträngigen ribonukleinsäure zur gezielten hemmung der expression eines vorgegebenen zielgens
|
DE10100588A1
(de)
*
|
2001-01-09 |
2002-07-18 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines Zielgens
|
GB0104948D0
(en)
*
|
2001-02-28 |
2001-04-18 |
Novartis Res Foundation |
Novel methods
|
US20050143333A1
(en)
*
|
2001-05-18 |
2005-06-30 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
|
US20050148530A1
(en)
|
2002-02-20 |
2005-07-07 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20050159378A1
(en)
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA)
|
US20050196767A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acis (siNA)
|
US20050159382A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)
|
WO2003102131A2
(en)
*
|
2002-04-22 |
2003-12-11 |
Sirna Therapeutics Inc. |
Nucleic acid mediated disruption of hiv fusogenic peptide interactions
|
US20050196765A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of checkpoint Kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)
|
WO2003070897A2
(en)
*
|
2002-02-20 |
2003-08-28 |
Ribozyme Pharmaceuticals, Incorporated |
RNA INTERFERENCE MEDIATED INHIBITION OF TNF AND TNF RECEPTOR SUPERFAMILY GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US9994853B2
(en)
|
2001-05-18 |
2018-06-12 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
US20050124566A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)
|
US20050203040A1
(en)
*
|
2001-05-18 |
2005-09-15 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)
|
US20050176025A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)
|
WO2003070969A2
(en)
*
|
2002-02-20 |
2003-08-28 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF BCL2 GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US20040198682A1
(en)
*
|
2001-11-30 |
2004-10-07 |
Mcswiggen James |
RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (siNA)
|
EP3231445A1
(en)
|
2001-05-18 |
2017-10-18 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
US20050182007A1
(en)
*
|
2001-05-18 |
2005-08-18 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
|
US20050014172A1
(en)
|
2002-02-20 |
2005-01-20 |
Ivan Richards |
RNA interference mediated inhibition of muscarinic cholinergic receptor gene expression using short interfering nucleic acid (siNA)
|
US20040019001A1
(en)
*
|
2002-02-20 |
2004-01-29 |
Mcswiggen James A. |
RNA interference mediated inhibition of protein typrosine phosphatase-1B (PTP-1B) gene expression using short interfering RNA
|
CA2526831C
(en)
*
|
2001-05-18 |
2012-07-31 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina)
|
WO2003070972A2
(en)
*
|
2002-02-20 |
2003-08-28 |
Sirna Therapeutics Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF CHROMOSOME TRANSLOCATION GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
WO2003070888A2
(en)
*
|
2002-02-20 |
2003-08-28 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of checkpoint kinase-1 (chk-1) gene expression using short interfering nucleic acid
|
US20050256068A1
(en)
|
2001-05-18 |
2005-11-17 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of stearoyl-CoA desaturase (SCD) gene expression using short interfering nucleic acid (siNA)
|
WO2003070197A2
(en)
*
|
2002-02-20 |
2003-08-28 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF TGF-BETA AND TGF-BETA RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US20030175950A1
(en)
*
|
2001-05-29 |
2003-09-18 |
Mcswiggen James A. |
RNA interference mediated inhibition of HIV gene expression using short interfering RNA
|
US20050288242A1
(en)
*
|
2001-05-18 |
2005-12-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)
|
US20050158735A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of proliferating cell nuclear antigen (PCNA) gene expression using short interfering nucleic acid (siNA)
|
WO2005014811A2
(en)
*
|
2003-08-08 |
2005-02-17 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF XIAP GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US20050159381A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of chromosome translocation gene expression using short interfering nucleic acid (siNA)
|
WO2003070884A2
(en)
*
|
2002-02-20 |
2003-08-28 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF MDR P-GLYCOPROTEIN GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US20050233997A1
(en)
*
|
2001-05-18 |
2005-10-20 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)
|
WO2003072705A2
(en)
*
|
2002-02-20 |
2003-09-04 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of cyclin d1 gene expression using short interfering nucleic acid (sina)
|
WO2004097020A2
(en)
*
|
2003-04-25 |
2004-11-11 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of map kinase gene expression
|
US7109165B2
(en)
|
2001-05-18 |
2006-09-19 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
US8008472B2
(en)
|
2001-05-29 |
2011-08-30 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of human immunodeficiency virus (HIV) gene expression using short interfering nucleic acid (siNA)
|
WO2003006477A1
(en)
|
2001-07-12 |
2003-01-23 |
University Of Massachusetts |
IN VIVO PRODUCTION OF SMALL INTERFERING RNAs THAT MEDIATE GENE SILENCING
|
US8022272B2
(en)
|
2001-07-13 |
2011-09-20 |
Sungene Gmbh & Co. Kgaa |
Expression cassettes for transgenic expression of nucleic acids
|
EP1432799A2
(en)
*
|
2001-07-17 |
2004-06-30 |
Anne Josephine Milner |
Silencing of gene expression by sirna
|
JP2005508306A
(ja)
|
2001-07-23 |
2005-03-31 |
ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ |
哺乳類における遺伝子発現のRNAiによる阻害に関する方法および組成物
|
US10590418B2
(en)
|
2001-07-23 |
2020-03-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for RNAi mediated inhibition of gene expression in mammals
|
US7456335B2
(en)
*
|
2001-09-03 |
2008-11-25 |
Basf Plant Science Gmbh |
Nucleic acid sequences and their use in methods for achieving pathogen resistance in plants
|
US7745418B2
(en)
|
2001-10-12 |
2010-06-29 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting viral replication
|
DE10163098B4
(de)
|
2001-10-12 |
2005-06-02 |
Alnylam Europe Ag |
Verfahren zur Hemmung der Replikation von Viren
|
US20040248835A1
(en)
*
|
2001-10-26 |
2004-12-09 |
Anja Krebs |
Use of a double-stranded ribonucleic acid for treating an infection with a positivestrand rna-virus
|
WO2003035083A1
(de)
*
|
2001-10-26 |
2003-05-01 |
Ribopharma Ag |
Medikament zur behandlung einer fibrotischen erkrankung durch rna interferenz
|
DE10230996A1
(de)
*
|
2001-10-26 |
2003-07-17 |
Ribopharma Ag |
Medikament zur Behandlung eines Pankreaskarzinoms
|
DE10202419A1
(de)
*
|
2002-01-22 |
2003-08-07 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines durch eine Chromosomen-Aberration entstandenen Zielgens
|
US20040014956A1
(en)
*
|
2002-02-01 |
2004-01-22 |
Sequitur, Inc. |
Double-stranded oligonucleotides
|
EP1572902B1
(en)
*
|
2002-02-01 |
2014-06-11 |
Life Technologies Corporation |
HIGH POTENCY siRNAS FOR REDUCING THE EXPRESSION OF TARGET GENES
|
US20060009409A1
(en)
*
|
2002-02-01 |
2006-01-12 |
Woolf Tod M |
Double-stranded oligonucleotides
|
GB2397062B
(en)
*
|
2002-02-20 |
2005-06-15 |
Sirna Therapeutics Inc |
RNA interference mediated inhibition of hepatitis c virus (HCV) gene expression using short interfering nucleic acid (siNA)
|
US7662952B2
(en)
|
2002-02-20 |
2010-02-16 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acid (siNA)
|
US7935812B2
(en)
|
2002-02-20 |
2011-05-03 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of hepatitis C virus (HCV) expression using short interfering nucleic acid (siNA)
|
US20090137510A1
(en)
*
|
2002-02-20 |
2009-05-28 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF NF-KAPPA B/ REL-A GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US20090253774A1
(en)
|
2002-02-20 |
2009-10-08 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF PLATELET DERIVED GROWTH FACTOR (PDGF) AND PLATELET DERIVED GROWTH FACTOR RECEPTOR (PDGFR) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US20090099117A1
(en)
|
2002-02-20 |
2009-04-16 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF MYOSTATIN GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US20090192105A1
(en)
|
2002-02-20 |
2009-07-30 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF INTERCELLULAR ADHESION MOLECULE (ICAM) GENE EXPRESSION USING SHORT INTERFERING NUCELIC ACID (siNA)
|
US7897757B2
(en)
|
2002-02-20 |
2011-03-01 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)
|
US7683165B2
(en)
|
2002-02-20 |
2010-03-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA)
|
US7678897B2
(en)
|
2002-02-20 |
2010-03-16 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA)
|
US20090247613A1
(en)
*
|
2002-02-20 |
2009-10-01 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF B-CELL CLL/LYMPHOMA-2 (BCL2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US8232383B2
(en)
*
|
2002-02-20 |
2012-07-31 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
US9657294B2
(en)
|
2002-02-20 |
2017-05-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
EP1741781A3
(en)
*
|
2002-02-20 |
2007-06-06 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
|
US7667029B2
(en)
|
2002-02-20 |
2010-02-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)
|
US8258288B2
(en)
|
2002-02-20 |
2012-09-04 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of respiratory syncytial virus (RSV) expression using short interfering nucleic acid (siNA)
|
US7691999B2
(en)
|
2002-02-20 |
2010-04-06 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering nucleic acid (siNA)
|
US7897752B2
(en)
|
2002-02-20 |
2011-03-01 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)
|
US7897753B2
(en)
|
2002-02-20 |
2011-03-01 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of XIAP gene expression using short interfering nucleic acid (siNA)
|
US9181551B2
(en)
|
2002-02-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
EP1501853A4
(en)
*
|
2002-02-20 |
2005-11-16 |
Sirna Therapeutics Inc |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION OF AN EPIDERMAL GROWTH FACTOR RECEPTOR USING SHORT INTERFERING NUCLEIC ACIDS
|
WO2003070966A2
(en)
*
|
2002-02-20 |
2003-08-28 |
Sirna Therapeutics, Inc |
RNA INTERFERENCE MEDIATED TARGET DISCOVERY AND TARGET VALIDATION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
AU2003207708A1
(en)
|
2002-02-20 |
2003-09-09 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of map kinase genes
|
US20090253773A1
(en)
|
2002-02-20 |
2009-10-08 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF TNF AND TNF RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US7928219B2
(en)
|
2002-02-20 |
2011-04-19 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (SINA)
|
US7893248B2
(en)
|
2002-02-20 |
2011-02-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA)
|
US7910724B2
(en)
|
2002-02-20 |
2011-03-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA)
|
US7928218B2
(en)
|
2002-02-20 |
2011-04-19 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)
|
EP1472265A4
(en)
*
|
2002-02-20 |
2005-06-15 |
Sirna Therapeutics Inc |
INHIBITION OF POLYCOMB GROUP PROTEIN EZH2 GENERATED BY RNA INTERFERENCE USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US7928220B2
(en)
|
2002-02-20 |
2011-04-19 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of stromal cell-derived factor-1 (SDF-1) gene expression using short interfering nucleic acid (siNA)
|
US7667030B2
(en)
|
2002-02-20 |
2010-02-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)
|
EP1710307A3
(en)
*
|
2002-02-20 |
2007-06-06 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
US8013143B2
(en)
|
2002-02-20 |
2011-09-06 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)
|
US8067575B2
(en)
|
2002-02-20 |
2011-11-29 |
Merck, Sharp & Dohme Corp. |
RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)
|
US7683166B2
(en)
|
2002-02-20 |
2010-03-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA)
|
US7700760B2
(en)
|
2002-02-20 |
2010-04-20 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)
|
US7795422B2
(en)
|
2002-02-20 |
2010-09-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)
|
MXPA04009134A
(es)
|
2002-03-21 |
2005-01-25 |
Monsanto Technology Llc |
Construcciones de acidos nucleicos y metodos para producir composiciones alteradas de aceite de semilla.
|
US7166771B2
(en)
|
2002-06-21 |
2007-01-23 |
Monsanto Technology Llc |
Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs
|
US7566813B2
(en)
|
2002-03-21 |
2009-07-28 |
Monsanto Technology, L.L.C. |
Nucleic acid constructs and methods for producing altered seed oil compositions
|
US20050222061A1
(en)
|
2002-04-18 |
2005-10-06 |
Schulte Ralf W |
Means and methods for the specific inhibition of genes in cells and tissue of the cns and/or eye
|
US20040180438A1
(en)
|
2002-04-26 |
2004-09-16 |
Pachuk Catherine J. |
Methods and compositions for silencing genes without inducing toxicity
|
AU2003283951A1
(en)
|
2002-05-23 |
2004-03-03 |
Ceptyr, Inc. |
Modulation of biological signal transduction by rna interference
|
US20100075423A1
(en)
*
|
2002-06-12 |
2010-03-25 |
Life Technologies Corporation |
Methods and compositions relating to polypeptides with rnase iii domains that mediate rna interference
|
AU2003243541A1
(en)
*
|
2002-06-12 |
2003-12-31 |
Ambion, Inc. |
Methods and compositions relating to labeled rna molecules that reduce gene expression
|
US20040248094A1
(en)
*
|
2002-06-12 |
2004-12-09 |
Ford Lance P. |
Methods and compositions relating to labeled RNA molecules that reduce gene expression
|
US7655790B2
(en)
|
2002-07-12 |
2010-02-02 |
Sirna Therapeutics, Inc. |
Deprotection and purification of oligonucleotides and their derivatives
|
US7148342B2
(en)
|
2002-07-24 |
2006-12-12 |
The Trustees Of The University Of Pennyslvania |
Compositions and methods for sirna inhibition of angiogenesis
|
US7399851B2
(en)
|
2002-07-25 |
2008-07-15 |
Dana Farber Cancer Institute, Inc. |
Composition and method for imaging cells
|
EP1527183B1
(de)
|
2002-07-26 |
2008-08-20 |
BASF Plant Science GmbH |
Neue selektionsverfahren
|
US20050042646A1
(en)
|
2002-08-05 |
2005-02-24 |
Davidson Beverly L. |
RNA interference suppresion of neurodegenerative diseases and methods of use thereof
|
EP1527176B2
(en)
|
2002-08-05 |
2017-03-22 |
Silence Therapeutics GmbH |
Further novel forms of interfering rna molecules
|
US20040023390A1
(en)
*
|
2002-08-05 |
2004-02-05 |
Davidson Beverly L. |
SiRNA-mediated gene silencing with viral vectors
|
US20040241854A1
(en)
|
2002-08-05 |
2004-12-02 |
Davidson Beverly L. |
siRNA-mediated gene silencing
|
DK1389637T3
(da)
*
|
2002-08-05 |
2012-09-03 |
Silence Therapeutics Ag |
Interfererende RNA-molekyler med stumpe ender
|
US20050255086A1
(en)
*
|
2002-08-05 |
2005-11-17 |
Davidson Beverly L |
Nucleic acid silencing of Huntington's Disease gene
|
US20080274989A1
(en)
|
2002-08-05 |
2008-11-06 |
University Of Iowa Research Foundation |
Rna Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof
|
WO2004014933A1
(en)
|
2002-08-07 |
2004-02-19 |
University Of Massachusetts |
Compositions for rna interference and methods of use thereof
|
EP2278018A3
(en)
|
2002-08-07 |
2012-01-04 |
BASF Plant Science GmbH |
Nucleic acid sequences encoding proteins associated with abiotic stress response
|
US20040029275A1
(en)
*
|
2002-08-10 |
2004-02-12 |
David Brown |
Methods and compositions for reducing target gene expression using cocktails of siRNAs or constructs expressing siRNAs
|
DE60328214D1
(de)
|
2002-08-12 |
2009-08-13 |
New England Biolabs Inc |
Verfahren und zusammensetzungen in verbindung mit gen-silencing
|
DE60325740D1
(de)
|
2002-08-14 |
2009-02-26 |
Silence Therapeutics Ag |
Verwendung von protein-kinase-n-beta
|
EP1393742A1
(en)
|
2002-08-14 |
2004-03-03 |
atugen AG |
Use of protein kinase N beta
|
US20060030534A1
(en)
|
2002-09-04 |
2006-02-09 |
Gabriele Dorn |
Treatment of neurological disorders by dsrna administration
|
US7956176B2
(en)
|
2002-09-05 |
2011-06-07 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
US20040053289A1
(en)
*
|
2002-09-09 |
2004-03-18 |
The Regents Of The University Of California |
Short interfering nucleic acid hybrids and methods thereof
|
US20040242518A1
(en)
*
|
2002-09-28 |
2004-12-02 |
Massachusetts Institute Of Technology |
Influenza therapeutic
|
CA2501752A1
(en)
|
2002-10-10 |
2004-04-22 |
Wyeth |
Compositions, organisms and methodologies employing a novel human kinase
|
CA2501333A1
(en)
|
2002-10-18 |
2004-04-29 |
Atugen Ag |
Factor involved in metastasis and uses thereof
|
US7208306B2
(en)
|
2002-10-24 |
2007-04-24 |
Wyeth |
Compositions employing a novel human protein phosphatase
|
US7521431B2
(en)
|
2002-11-01 |
2009-04-21 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for siRNA inhibition of HIF-1 alpha
|
EP1560839A4
(en)
|
2002-11-05 |
2008-04-23 |
Isis Pharmaceuticals Inc |
CHIMERIC OLIGOMER COMPOUNDS AND THEIR USE IN GENE MODULATION
|
AU2003287502B2
(en)
|
2002-11-05 |
2010-12-09 |
Isis Pharmaceuticals, Inc. |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
|
US9150606B2
(en)
|
2002-11-05 |
2015-10-06 |
Isis Pharmaceuticals, Inc. |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
|
US9150605B2
(en)
|
2002-11-05 |
2015-10-06 |
Isis Pharmaceuticals, Inc. |
Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
|
AU2003291753B2
(en)
|
2002-11-05 |
2010-07-08 |
Isis Pharmaceuticals, Inc. |
Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation
|
CA2505403A1
(en)
*
|
2002-11-07 |
2004-05-27 |
Lung-Ji Chang |
Modified dendritic cells
|
US10011836B2
(en)
|
2002-11-14 |
2018-07-03 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
US9771586B2
(en)
|
2002-11-14 |
2017-09-26 |
Thermo Fisher Scientific Inc. |
RNAi targeting ZNF205
|
US9719094B2
(en)
|
2002-11-14 |
2017-08-01 |
Thermo Fisher Scientific Inc. |
RNAi targeting SEC61G
|
US9839649B2
(en)
|
2002-11-14 |
2017-12-12 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
WO2006006948A2
(en)
|
2002-11-14 |
2006-01-19 |
Dharmacon, Inc. |
METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY
|
US9879266B2
(en)
|
2002-11-14 |
2018-01-30 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
US9719092B2
(en)
|
2002-11-14 |
2017-08-01 |
Thermo Fisher Scientific Inc. |
RNAi targeting CNTD2
|
US9228186B2
(en)
|
2002-11-14 |
2016-01-05 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
CA2505416A1
(en)
|
2002-11-21 |
2004-06-10 |
Wyeth |
Methods for diagnosing rcc and other solid tumors
|
JP4526228B2
(ja)
*
|
2002-11-22 |
2010-08-18 |
隆 森田 |
RNAiによる新規治療法および治療剤
|
AU2003290664A1
(en)
|
2002-11-27 |
2004-06-23 |
Wei Liu |
Compositions, organisms and methodologies employing a novel human kinase
|
ATE477337T1
(de)
|
2003-01-16 |
2010-08-15 |
Univ Pennsylvania |
Zusammensetzungen und verfahren zur sirna-hemmung von icam-1
|
WO2004074321A2
(en)
|
2003-02-14 |
2004-09-02 |
Sagres Discovery, Inc. |
Therapeutic gpcr targets in cancer
|
CA2518475C
(en)
|
2003-03-07 |
2014-12-23 |
Alnylam Pharmaceuticals, Inc. |
Irna agents comprising asymmetrical modifications
|
DE602004023279D1
(de)
*
|
2003-03-21 |
2009-11-05 |
Santaris Pharma As |
Analoga kurzer interferierender rna (sirna)
|
AU2004229519B2
(en)
|
2003-04-09 |
2011-07-21 |
Alnylam Pharmaceuticals, Inc. |
iRNA conjugates
|
US20090298914A1
(en)
*
|
2003-04-15 |
2009-12-03 |
Sirna Therapeutics, Inc. |
RNA Interference Mediated Inhibition of Severe Acute Respiratory Syndrome (SARS) Virus Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
WO2004092383A2
(en)
*
|
2003-04-15 |
2004-10-28 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF SEVERE ACUTE RESPIRATORY SYNDROME (SARS) VIRUS GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US7851615B2
(en)
|
2003-04-17 |
2010-12-14 |
Alnylam Pharmaceuticals, Inc. |
Lipophilic conjugated iRNA agents
|
EP1625138A4
(en)
|
2003-04-17 |
2010-06-23 |
Alnylam Pharmaceuticals Inc |
PROTECTED MONOMERS
|
US8017762B2
(en)
|
2003-04-17 |
2011-09-13 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
US7723509B2
(en)
|
2003-04-17 |
2010-05-25 |
Alnylam Pharmaceuticals |
IRNA agents with biocleavable tethers
|
US8796436B2
(en)
|
2003-04-17 |
2014-08-05 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
JP4597976B2
(ja)
|
2003-04-17 |
2010-12-15 |
アルナイラム ファーマシューティカルズ インコーポレイテッド |
修飾iRNA剤
|
JP2006523464A
(ja)
|
2003-04-18 |
2006-10-19 |
ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア |
アンジオポエチン1、2、及びそれらの受容体TIE2のsiRNA阻害のための組成物及びその方法
|
CN1984921B
(zh)
|
2003-06-03 |
2010-06-16 |
Isis药物公司 |
存活蛋白表达的调节
|
US7595306B2
(en)
|
2003-06-09 |
2009-09-29 |
Alnylam Pharmaceuticals Inc |
Method of treating neurodegenerative disease
|
AU2004263830B2
(en)
|
2003-06-13 |
2008-12-18 |
Alnylam Pharmaceuticals, Inc. |
Double-stranded ribonucleic acid with increased effectiveness in an organism
|
AU2004252559B2
(en)
*
|
2003-06-25 |
2010-07-29 |
Gencia Corporation |
Modified vectors for organelle transfection
|
CA2528963A1
(en)
*
|
2003-06-27 |
2005-01-13 |
Sirna Therapeutics, Inc. |
Rna interference mediated treatment of alzheimer's disease using short interfering nucleic acid (sina)
|
WO2005007859A2
(en)
*
|
2003-07-11 |
2005-01-27 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF ACETYL-COA CARBOXYLASE GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
CA2532312A1
(en)
|
2003-08-01 |
2005-02-17 |
Basf Plant Science Gmbh |
Process for the production of fine chemicals in plants
|
AU2004269150C1
(en)
|
2003-08-28 |
2010-11-18 |
Novartis Ag |
Interfering RNA duplex having blunt-ends and 3'-modifications
|
US20070202505A1
(en)
*
|
2003-09-08 |
2007-08-30 |
Alex Chenchik |
Methods for gene function analysis
|
WO2005045037A2
(en)
*
|
2003-10-23 |
2005-05-19 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF 5-ALPHA REDUCTASE AND ANDROGEN RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
WO2005047506A1
(en)
|
2003-11-04 |
2005-05-26 |
Geron Corporation |
Rna amidates and thioamidates for rnai
|
AU2004294567A1
(en)
*
|
2003-11-26 |
2005-06-16 |
University Of Massachusetts |
Sequence-specific inhibition of small RNA function
|
CN1922332B
(zh)
|
2003-12-31 |
2013-06-12 |
宾夕法尼亚州研究基金会 |
预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法
|
US20080249039A1
(en)
*
|
2004-01-30 |
2008-10-09 |
Santaris Pharma A/S |
Modified Short Interfering Rna (Modified Sirna)
|
JP4755113B2
(ja)
|
2004-01-30 |
2011-08-24 |
クアーク・ファーマスーティカルス、インコーポレイテッド |
線維性状態およびその他の疾患の治療のための、オリゴリボヌクレオチドおよびその使用方法
|
US20070269889A1
(en)
*
|
2004-02-06 |
2007-11-22 |
Dharmacon, Inc. |
Stabilized siRNAs as transfection controls and silencing reagents
|
US20090280567A1
(en)
*
|
2004-02-06 |
2009-11-12 |
Dharmacon, Inc. |
Stabilized sirnas as transfection controls and silencing reagents
|
EP1747284A4
(en)
|
2004-02-06 |
2009-03-11 |
Wyeth Corp |
DIAGNOSTICS AND THERAPEUTICS OF CANCER
|
US7858769B2
(en)
|
2004-02-10 |
2010-12-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using multifunctional short interfering nucleic acid (multifunctional siNA)
|
US20060019914A1
(en)
|
2004-02-11 |
2006-01-26 |
University Of Tennessee Research Foundation |
Inhibition of tumor growth and invasion by anti-matrix metalloproteinase DNAzymes
|
ES2368741T3
(es)
|
2004-02-25 |
2011-11-21 |
Dana-Farber Cancer Institute, Inc. |
Inhibidores del receptor 1 del factor de crecimiento de tipo insulina para inhibir el crecimiento de células tumorales.
|
WO2005089224A2
(en)
|
2004-03-12 |
2005-09-29 |
Alnylam Pharmaceuticals, Inc. |
iRNA AGENTS TARGETING VEGF
|
KR101147147B1
(ko)
*
|
2004-04-01 |
2012-05-25 |
머크 샤프 앤드 돔 코포레이션 |
Rna 간섭의 오프 타겟 효과 감소를 위한 변형된폴리뉴클레오타이드
|
RS52918B
(en)
|
2004-04-02 |
2014-02-28 |
The Regents Of The University Of California |
PROCEDURES AND MIXTURES FOR TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH ALFA V BETA 5 INTEGRINE
|
WO2005105157A2
(en)
|
2004-04-23 |
2005-11-10 |
The Trustees Of Columbia University In The City Ofnew York |
INHIBITION OF HAIRLESS PROTEIN mRNA
|
DE102004025881A1
(de)
|
2004-05-19 |
2006-01-05 |
Beiersdorf Ag |
Oligoribonukleotide zur Beeinflussung des Haarwachstums
|
US10508277B2
(en)
|
2004-05-24 |
2019-12-17 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
JP5435864B2
(ja)
|
2004-05-28 |
2014-03-05 |
アシュラジェン インコーポレイテッド |
マイクロrnaに関与する方法および組成物
|
US8394947B2
(en)
|
2004-06-03 |
2013-03-12 |
Isis Pharmaceuticals, Inc. |
Positionally modified siRNA constructs
|
EP1602926A1
(en)
|
2004-06-04 |
2005-12-07 |
University of Geneva |
Novel means and methods for the treatment of hearing loss and phantom hearing
|
US20060003410A1
(en)
*
|
2004-06-10 |
2006-01-05 |
Lee-Ming Chuang |
Prostaglandin reductase
|
EP2298896A1
(en)
|
2004-06-22 |
2011-03-23 |
The Board of Trustees of the University of Illinois |
Methods of inhibiting tumor cell proliferation with FOXM1 siRNA
|
CA2572439A1
(en)
|
2004-07-02 |
2006-01-12 |
Protiva Biotherapeutics, Inc. |
Immunostimulatory sirna molecules and uses therefor
|
AU2005321630A1
(en)
|
2004-07-02 |
2006-07-06 |
Metanomics Gmbh |
Process for the production of fine chemicals
|
US7968762B2
(en)
|
2004-07-13 |
2011-06-28 |
Van Andel Research Institute |
Immune-compromised transgenic mice expressing human hepatocyte growth factor (hHGF)
|
US20060024677A1
(en)
|
2004-07-20 |
2006-02-02 |
Morris David W |
Novel therapeutic targets in cancer
|
US20100132058A1
(en)
|
2004-07-23 |
2010-05-27 |
Diatchenko Luda B |
Methods and materials for determining pain sensitivity and predicting and treating related disorders
|
CA2834275A1
(en)
|
2004-08-02 |
2006-02-09 |
Basf Plant Science Gmbh |
Method for isolation of transcription termination sequences
|
US7846438B2
(en)
|
2004-08-03 |
2010-12-07 |
Biogen Idec Ma Inc. |
Methods of promoting neurite outgrowth with soluble TAJ polypeptides
|
JP5192234B2
(ja)
|
2004-08-10 |
2013-05-08 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
化学修飾オリゴヌクレオチド
|
CN101123994B
(zh)
|
2004-08-16 |
2012-11-14 |
夸克医药公司 |
Rtp801的抑制剂的治疗性用途
|
EP1786905B1
(en)
|
2004-08-18 |
2011-08-03 |
Lorus Therapeutics Inc. |
Small interfering rna molecules against ribonucleotide reductase and uses thereof
|
US7884086B2
(en)
|
2004-09-08 |
2011-02-08 |
Isis Pharmaceuticals, Inc. |
Conjugates for use in hepatocyte free uptake assays
|
US20090170794A1
(en)
|
2004-09-10 |
2009-07-02 |
Somagenics Inc. |
Small interfering rnas that efficiently inhibit viral expression and methods of use thereof
|
AU2005286427B2
(en)
|
2004-09-24 |
2011-09-15 |
Basf Plant Science Gmbh |
Plant cells and plants with increased tolerance to environmental stress
|
CN102643818B
(zh)
|
2004-09-28 |
2014-04-09 |
夸克制药公司 |
寡核糖核苷酸以及其用于治疗脱发、肾衰竭和其它疾病的方法
|
EP1645633B1
(en)
|
2004-10-05 |
2011-09-21 |
SunGene GmbH |
Constitutive expression cassettes for regulation of plant expression
|
WO2006044480A2
(en)
|
2004-10-13 |
2006-04-27 |
University Of Georgia Research Foundation, Inc. |
Nematode resistant transgenic plants
|
WO2007001448A2
(en)
|
2004-11-04 |
2007-01-04 |
Massachusetts Institute Of Technology |
Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
|
EP1655364A3
(en)
|
2004-11-05 |
2006-08-02 |
BASF Plant Science GmbH |
Expression cassettes for seed-preferential expression in plants
|
DK2302055T3
(da)
|
2004-11-12 |
2014-10-13 |
Asuragen Inc |
Fremgangsmåder og sammensætninger involverende miRNA og miRNA-inhibitormolekyler
|
US7923206B2
(en)
*
|
2004-11-22 |
2011-04-12 |
Dharmacon, Inc. |
Method of determining a cellular response to a biological agent
|
US7923207B2
(en)
|
2004-11-22 |
2011-04-12 |
Dharmacon, Inc. |
Apparatus and system having dry gene silencing pools
|
US7935811B2
(en)
*
|
2004-11-22 |
2011-05-03 |
Dharmacon, Inc. |
Apparatus and system having dry gene silencing compositions
|
EP2163631B1
(en)
|
2004-11-25 |
2013-05-22 |
SunGene GmbH |
Expression cassettes for guard cell-preferential expression in plants
|
EP1666599A3
(en)
|
2004-12-04 |
2006-07-12 |
SunGene GmbH |
Expression cassettes for mesophyll- and/or epidermis-preferential expression in plants
|
EP2072620B1
(en)
|
2004-12-08 |
2013-05-08 |
SunGene GmbH |
Expression casstettes for vascular tissue-preferential expression in plants
|
EP1669456A3
(en)
|
2004-12-11 |
2006-07-12 |
SunGene GmbH |
Expression cassettes for meristem-preferential expression in plants
|
CA2585798A1
(en)
|
2004-12-17 |
2006-06-17 |
Metanomics Gmbh |
Process for the control of production of fine chemicals
|
US20060142228A1
(en)
*
|
2004-12-23 |
2006-06-29 |
Ambion, Inc. |
Methods and compositions concerning siRNA's as mediators of RNA interference
|
TWI386225B
(zh)
|
2004-12-23 |
2013-02-21 |
Alcon Inc |
用於治療眼睛病症的結締組織生長因子(CTGF)RNA干擾(RNAi)抑制技術
|
BRPI0519468A2
(pt)
|
2004-12-27 |
2009-01-27 |
Silence Therapeutics Ag |
complexos de lipÍdeos revestido e seu uso
|
MX2007008065A
(es)
*
|
2004-12-30 |
2008-03-04 |
Todd M Hauser |
Composiciones y metodos para modular la expresion genica usando oligonucleotidos autoprotegidos.
|
WO2006072887A1
(en)
|
2005-01-05 |
2006-07-13 |
Eyegate Pharma Sa |
Ocular iontophoresis device for delivering sirna and aptamers
|
DK1841793T3
(da)
|
2005-01-07 |
2010-07-19 |
Diadexus Inc |
Ovr110-antistofsammensætninger og fremgangsmåder til anvendelse deraf
|
TW200639253A
(en)
|
2005-02-01 |
2006-11-16 |
Alcon Inc |
RNAi-mediated inhibition of ocular targets
|
CN103184218A
(zh)
|
2005-02-09 |
2013-07-03 |
巴斯福植物科学有限公司 |
在单子叶植物中调控表达的表达盒
|
CA2598307C
(en)
|
2005-02-26 |
2014-12-30 |
Basf Plant Science Gmbh |
Expression cassettes for seed-preferential expression in plants
|
JPWO2006093083A1
(ja)
*
|
2005-03-03 |
2008-08-07 |
和光純薬工業株式会社 |
架橋剤、架橋法、遺伝子発現調節法及び遺伝子機能調査法
|
CA2599405A1
(en)
|
2005-03-08 |
2006-09-14 |
Basf Plant Science Gmbh |
Expression enhancing intron sequences
|
JP2008533050A
(ja)
|
2005-03-11 |
2008-08-21 |
アルコン,インコーポレイテッド |
緑内障を処置するためのフリッツルド関連蛋白質―1のrnai媒介性阻害
|
US20060223777A1
(en)
*
|
2005-03-29 |
2006-10-05 |
Dharmacon, Inc. |
Highly functional short hairpin RNA
|
AU2006230436B2
(en)
|
2005-03-31 |
2011-11-24 |
Calando Pharmaceuticals, Inc. |
Inhibitors of ribonucleotide reductase subunit 2 and uses thereof
|
US20090220495A1
(en)
|
2005-04-07 |
2009-09-03 |
Abdallah Fanidi |
Cancer Related Genes (PRLR)
|
US20090214536A1
(en)
|
2005-04-07 |
2009-08-27 |
Guoying Yu |
CACNA1E in Cancer Diagnosis, Detection and Treatment
|
JP4967137B2
(ja)
*
|
2005-04-18 |
2012-07-04 |
国立大学法人浜松医科大学 |
癌治療用組成物
|
WO2006113743A2
(en)
*
|
2005-04-18 |
2006-10-26 |
Massachusetts Institute Of Technology |
Compositions and methods for rna interference with sialidase expression and uses thereof
|
EP1882037A2
(en)
|
2005-05-10 |
2008-01-30 |
BASF Plant Science GmbH |
Expression cassettes for seed-preferential expression in plants
|
CA2605508A1
(en)
|
2005-05-12 |
2006-11-23 |
Wisconsin Alumni Research Foundation |
Blockade of pin1 prevents cytokine production by activated immune cells
|
FR2885808B1
(fr)
|
2005-05-19 |
2007-07-06 |
Oreal |
Vectorisation de dsrna par des particules cationiques et utilisation topique.
|
US7994399B2
(en)
|
2005-06-23 |
2011-08-09 |
Basf Plant Science Gmbh |
Methods for the production of stably transformed, fertile Zea mays plants
|
US8703769B2
(en)
|
2005-07-15 |
2014-04-22 |
The University Of North Carolina At Chapel Hill |
Use of EGFR inhibitors to prevent or treat obesity
|
EP1764107A1
(en)
*
|
2005-09-14 |
2007-03-21 |
Gunther Hartmann |
Compositions comprising immunostimulatory RNA oligonucleotides and methods for producing said RNA oligonucleotides
|
CN101268194A
(zh)
|
2005-09-20 |
2008-09-17 |
巴斯福植物科学有限公司 |
使用ta-siRNA调控基因表达的方法
|
EP1934348B1
(en)
|
2005-10-11 |
2018-05-02 |
Ben-Gurion University Of The Negev Research And Development Authority |
Compositions for silencing the expression of vdac1 and uses thereof
|
CA2627025A1
(en)
|
2005-10-28 |
2007-05-03 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of huntingtin gene
|
WO2007051303A1
(en)
|
2005-11-02 |
2007-05-10 |
Protiva Biotherapeutics, Inc. |
MODIFIED siRNA MOLECULES AND USES THEREOF
|
WO2007056326A2
(en)
|
2005-11-04 |
2007-05-18 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of nav1.8 gene
|
AU2006311089C1
(en)
|
2005-11-08 |
2012-11-08 |
Basf Plant Science Gmbh |
Use of armadillo repeat (ARM1) polynucleotides for obtaining pathogen resistance in plants
|
AU2006311730B2
(en)
|
2005-11-09 |
2010-12-02 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of Factor V Leiden mutant gene
|
EP2468901B1
(en)
|
2005-11-29 |
2017-04-05 |
Cambridge Enterprise Limited |
Markers for breast cancer
|
WO2007070682A2
(en)
|
2005-12-15 |
2007-06-21 |
Massachusetts Institute Of Technology |
System for screening particles
|
DE602006020617D1
(de)
|
2005-12-30 |
2011-04-21 |
Evonik Roehm Gmbh |
Lactoferrin-peptide, geeignet als in die zelle eindringende peptide
|
CA2636070A1
(en)
|
2006-01-06 |
2007-08-02 |
North Carolina State University |
Cyst nematode resistant transgenic plants
|
WO2007080143A1
(en)
|
2006-01-12 |
2007-07-19 |
Basf Plant Science Gmbh |
Use of stomatin (stm1) polynucleotides for achieving a pathogen resistance in plants
|
US7825099B2
(en)
|
2006-01-20 |
2010-11-02 |
Quark Pharmaceuticals, Inc. |
Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
|
DOP2007000015A
(es)
|
2006-01-20 |
2007-08-31 |
Quark Biotech Inc |
Usos terapéuticos de inhibidores de rtp801
|
BRPI0707276B1
(pt)
|
2006-01-27 |
2021-08-31 |
Biogen Ma Inc |
Polipeptídeo de fusão antagonista de receptor nogo
|
CA2638837A1
(en)
*
|
2006-01-27 |
2007-08-02 |
Santaris Pharma A/S |
Lna modified phosphorothiolated oligonucleotides
|
CN101421406B
(zh)
|
2006-02-13 |
2016-08-31 |
孟山都技术有限公司 |
用于产生改变的种子油组成的核酸构建体和方法
|
US7910566B2
(en)
|
2006-03-09 |
2011-03-22 |
Quark Pharmaceuticals Inc. |
Prevention and treatment of acute renal failure and other kidney diseases by inhibition of p53 by siRNA
|
AU2007229161B2
(en)
|
2006-03-23 |
2012-07-12 |
Roche Innovation Center Copenhagen A/S |
Small internally segmented interfering RNA
|
FR2898908A1
(fr)
|
2006-03-24 |
2007-09-28 |
Agronomique Inst Nat Rech |
Procede de preparation de cellules aviaires differenciees et genes impliques dans le maintien de la pluripotence
|
US8968702B2
(en)
|
2006-03-30 |
2015-03-03 |
Duke University |
Inhibition of HIF-1 activation for anti-tumor and anti-inflammatory responses
|
JP5704741B2
(ja)
|
2006-03-31 |
2015-04-22 |
アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. |
Eg5遺伝子発現の抑制のための組成物および方法
|
EP2090662A3
(en)
|
2006-04-05 |
2012-10-31 |
Metanomics GmbH |
Process for the production of a fine chemical
|
TW200813231A
(en)
|
2006-04-13 |
2008-03-16 |
Novartis Vaccines & Diagnostic |
Methods of treating, diagnosing or detecting cancer
|
JP4812874B2
(ja)
|
2006-04-28 |
2011-11-09 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
Jcウイルス遺伝子の発現を抑制するための組成物および方法
|
GB0608838D0
(en)
|
2006-05-04 |
2006-06-14 |
Novartis Ag |
Organic compounds
|
AU2007249329C1
(en)
|
2006-05-11 |
2011-03-24 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of the PCSK9 gene
|
EP2019691B1
(en)
|
2006-05-15 |
2020-08-12 |
Massachusetts Institute of Technology |
Polymers for functional particles
|
EP2392583A1
(en)
|
2006-05-19 |
2011-12-07 |
Alnylam Europe AG. |
RNAi modulation of Aha and therapeutic uses thereof
|
EP2584051B1
(en)
|
2006-05-22 |
2014-07-16 |
Alnylam Pharmaceuticals Inc. |
Compositions and methods for inhibiting expressions of IKK-B gene
|
WO2007141796A2
(en)
|
2006-06-09 |
2007-12-13 |
Quark Pharmaceuticals, Inc. |
Therapeutic uses of inhibitors of rtp801l
|
US7915399B2
(en)
|
2006-06-09 |
2011-03-29 |
Protiva Biotherapeutics, Inc. |
Modified siRNA molecules and uses thereof
|
WO2007150030A2
(en)
|
2006-06-23 |
2007-12-27 |
Massachusetts Institute Of Technology |
Microfluidic synthesis of organic nanoparticles
|
EP2037737B1
(en)
|
2006-07-11 |
2014-04-02 |
University Of Medicine And Dentistry Of New Jersey |
Cell membrane repair proteins, nucleic acids encoding the same and associated methods of use
|
WO2008009477A2
(en)
|
2006-07-21 |
2008-01-24 |
Silence Therapeutics Ag |
Means for inhibiting the expression of protein kinase 3
|
US7666423B2
(en)
|
2006-07-28 |
2010-02-23 |
Children's Memorial Hospital |
Methods of inhibiting tumor cell aggressiveness using the microenvironment of human embryonic stem cells
|
US7872118B2
(en)
|
2006-09-08 |
2011-01-18 |
Opko Ophthalmics, Llc |
siRNA and methods of manufacture
|
WO2008036638A2
(en)
|
2006-09-18 |
2008-03-27 |
Alnylam Pharmaceuticals, Inc. |
Rnai modulation of scap and therapeutic uses thereof
|
WO2008036933A2
(en)
|
2006-09-21 |
2008-03-27 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of the hamp gene
|
JP5352462B2
(ja)
*
|
2006-09-22 |
2013-11-27 |
ダーマコン, インコーポレイテッド |
二本鎖オリゴヌクレオチド複合体、rna干渉による遺伝子サイレンシング方法、および医薬品組成物
|
JP2010507387A
(ja)
|
2006-10-25 |
2010-03-11 |
クアーク・ファーマスーティカルス、インコーポレイテッド |
新規のsiRNAおよびその使用方法
|
ATE508191T1
(de)
|
2006-11-01 |
2011-05-15 |
Medical Res And Infrastructure Fund Of The Tel Aviv Sourasky Medical Ct |
Adipozytenspezifische konstrukte und verfahren zur hemmung der expression von blutplättchen-typ- 12-lipoxygenase
|
US20080199475A1
(en)
|
2006-11-27 |
2008-08-21 |
Patrys Limited |
Novel glycosylated peptide target in neoplastic cells
|
WO2008067283A2
(en)
|
2006-11-27 |
2008-06-05 |
Diadexus, Inc. |
Ovr110 antibody compositions and methods of use
|
EP2097448A4
(en)
|
2006-12-22 |
2010-07-21 |
Univ Utah Res Found |
METHOD FOR DETECTING DISEASES AND OCULAR DISEASE CONDITIONS AND TREATMENT THEREOF
|
US8592652B2
(en)
|
2007-01-15 |
2013-11-26 |
Basf Plant Science Gmbh |
Use of subtilisin-like RNR9 polynucleotide for achieving pathogen resistance in plants
|
CA2676143A1
(en)
|
2007-01-26 |
2008-07-31 |
University Of Louisville Research Foundation, Inc. |
Modification of exosomal components for use as a vaccine
|
US9217129B2
(en)
|
2007-02-09 |
2015-12-22 |
Massachusetts Institute Of Technology |
Oscillating cell culture bioreactor
|
EP2074219B1
(en)
|
2007-02-16 |
2013-11-20 |
BASF Plant Science GmbH |
Nucleic acid sequences for regulation of embryo-specific expression in monocotyledonous plants
|
EP2137205A2
(en)
|
2007-02-26 |
2009-12-30 |
Quark Pharmaceuticals, Inc. |
Inhibitors of rtp801 and their use in disease treatment
|
EP2125898B1
(en)
|
2007-03-14 |
2013-05-15 |
Novartis AG |
Apcdd1 inhibitors for treating, diagnosing or detecting cancer
|
US7812002B2
(en)
|
2007-03-21 |
2010-10-12 |
Quark Pharmaceuticals, Inc. |
Oligoribonucleotide inhibitors of NRF2 and methods of use thereof for treatment of cancer
|
JP5759673B2
(ja)
|
2007-03-21 |
2015-08-05 |
ブルックヘブン サイエンス アソシエイツ,エルエルシー |
組み合わされたヘアピン−アンチセンス組成物および発現を調節するための方法
|
PE20090064A1
(es)
|
2007-03-26 |
2009-03-02 |
Novartis Ag |
Acido ribonucleico de doble cadena para inhibir la expresion del gen e6ap humano y composicion farmaceutica que lo comprende
|
AU2008232891B2
(en)
|
2007-03-29 |
2012-01-12 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a gene from the Ebola
|
EP2144600A4
(en)
|
2007-04-04 |
2011-03-16 |
Massachusetts Inst Technology |
POLY (AMINIC ACID) TARGET MOLECULES
|
MX2009011218A
(es)
|
2007-04-17 |
2010-02-11 |
Baxter Int |
Microparticulas de acido nucleico para administracion pulmonar.
|
WO2009014565A2
(en)
|
2007-04-26 |
2009-01-29 |
Ludwig Institute For Cancer Research, Ltd. |
Methods for diagnosing and treating astrocytomas
|
WO2008137115A1
(en)
|
2007-05-03 |
2008-11-13 |
The Brigham And Women's Hospital, Inc. |
Multipotent stem cells and uses thereof
|
JP5296328B2
(ja)
|
2007-05-09 |
2013-09-25 |
独立行政法人理化学研究所 |
1本鎖環状rnaおよびその製造方法
|
DE112008001453T5
(de)
|
2007-05-22 |
2010-04-29 |
Basf Plant Science Gmbh |
Pflanzenzellen und Pflanzen mit erhöhter Toleranz und/oder Resistenz gegenüber Umweltstress und erhöhter Biomasseproduktion-KO
|
EP2162538B1
(en)
|
2007-05-22 |
2016-04-20 |
Arcturus Therapeutics, Inc. |
Oligomers for therapeutics
|
US8097422B2
(en)
|
2007-06-20 |
2012-01-17 |
Salk Institute For Biological Studies |
Kir channel modulators
|
EP2170403B1
(en)
|
2007-06-27 |
2014-04-16 |
Quark Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of pro-apoptotic genes
|
CN101688206B
(zh)
|
2007-07-05 |
2013-05-15 |
诺瓦提斯公司 |
用于治疗病毒感染的dsRNA
|
US9689031B2
(en)
|
2007-07-14 |
2017-06-27 |
Ionian Technologies, Inc. |
Nicking and extension amplification reaction for the exponential amplification of nucleic acids
|
WO2009012263A2
(en)
|
2007-07-18 |
2009-01-22 |
The Trustees Of Columbia University In The City Of New York |
Tissue-specific micrornas and compositions and uses thereof
|
MX2010001307A
(es)
|
2007-08-02 |
2010-07-30 |
Novimmune Sa |
Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos.
|
CN102316888A
(zh)
*
|
2007-08-23 |
2012-01-11 |
利兰斯坦福青年大学托管委员会 |
突触发生的调控
|
US8183221B2
(en)
|
2007-09-05 |
2012-05-22 |
Medtronic, Inc. |
Suppression of SCN9A gene expression and/or function for the treatment of pain
|
EP2198050A1
(en)
|
2007-09-14 |
2010-06-23 |
Asuragen, INC. |
Micrornas differentially expressed in cervical cancer and uses thereof
|
WO2009039300A2
(en)
*
|
2007-09-18 |
2009-03-26 |
Intradigm Corporation |
Compositions comprising hif-1 alpha sirna and methods of use thereof
|
CA2704737A1
(en)
*
|
2007-09-18 |
2009-09-03 |
Intradigm Corporation |
Compositions comprising k-ras sirna and methods of use
|
WO2009039173A2
(en)
|
2007-09-19 |
2009-03-26 |
Applied Biosystems Inc. |
SiRNA SEQUENCE-INDEPENDENT MODIFICATION FORMATS FOR REDUCING OFF-TARGET PHENOTYPIC EFFECTS IN RNAi, AND STABILIZED FORMS THEREOF
|
PL2644594T3
(pl)
|
2007-09-28 |
2018-01-31 |
Pfizer |
Ukierunkowanie na komórki nowotworowe za pomocą nanocząstek
|
RU2487716C2
(ru)
|
2007-10-03 |
2013-07-20 |
Кварк Фармасьютикалс, Инк. |
Новые структуры малых интерферирующих рнк (sirna)
|
BRPI0817664A2
(pt)
|
2007-10-12 |
2015-03-24 |
Massachusetts Inst Technology |
Nanopartículas, método para preparar nanopartículas e método para tratar terapeuticamente ou profilaticamente um indivíduo
|
US8097712B2
(en)
|
2007-11-07 |
2012-01-17 |
Beelogics Inc. |
Compositions for conferring tolerance to viral disease in social insects, and the use thereof
|
EP4074344A1
(en)
|
2007-12-04 |
2022-10-19 |
Arbutus Biopharma Corporation |
Targeting lipids
|
US7871985B2
(en)
|
2007-12-10 |
2011-01-18 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of factor VII gene
|
US20100204305A1
(en)
*
|
2007-12-11 |
2010-08-12 |
Lorus Therapeutics Inc. |
Small interfering rna molecules against ribonucleotide reductase and uses thereof
|
US8614311B2
(en)
|
2007-12-12 |
2013-12-24 |
Quark Pharmaceuticals, Inc. |
RTP801L siRNA compounds and methods of use thereof
|
EP2240587A2
(en)
*
|
2007-12-21 |
2010-10-20 |
BASF Plant Science GmbH |
Plants with increased yield (ko nue)
|
EP2242854A4
(en)
*
|
2008-01-15 |
2012-08-15 |
Quark Pharmaceuticals Inc |
COMPOUNDS AND USES THEREOF
|
US8188060B2
(en)
|
2008-02-11 |
2012-05-29 |
Dharmacon, Inc. |
Duplex oligonucleotides with enhanced functionality in gene regulation
|
WO2009102427A2
(en)
|
2008-02-11 |
2009-08-20 |
Rxi Pharmaceuticals Corp. |
Modified rnai polynucleotides and uses thereof
|
EA019531B1
(ru)
|
2008-03-05 |
2014-04-30 |
Элнилэм Фармасьютикалз, Инк. |
КОМПОЗИЦИИ И СПОСОБЫ ИНГИБИРОВАНИЯ ЭКСПРЕССИИ ГЕНОВ Eg5 И VEGF
|
WO2009114726A1
(en)
*
|
2008-03-12 |
2009-09-17 |
Intradigm Corporation |
Compositions comprising notch1 sirna and methods of use thereof
|
CA2720473A1
(en)
|
2008-04-04 |
2009-10-08 |
Calando Pharmaceuticals, Inc. |
Compositions and use of epas1 inhibitors
|
EP3604533A1
(en)
|
2008-04-11 |
2020-02-05 |
Arbutus Biopharma Corporation |
Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
|
US8278287B2
(en)
|
2008-04-15 |
2012-10-02 |
Quark Pharmaceuticals Inc. |
siRNA compounds for inhibiting NRF2
|
GB0807018D0
(en)
|
2008-04-17 |
2008-05-21 |
Fusion Antibodies Ltd |
Antibodies and treatment
|
EP2285960B1
(en)
|
2008-05-08 |
2015-07-08 |
Asuragen, INC. |
Compositions and methods related to mir-184 modulation of neovascularization or angiogenesis
|
JP5524189B2
(ja)
|
2008-06-06 |
2014-06-18 |
クォーク ファーマシューティカルズ インコーポレーティッド |
耳障害治療のための組成物および方法
|
TWI455944B
(zh)
|
2008-07-01 |
2014-10-11 |
Daiichi Sankyo Co Ltd |
雙股多核苷酸
|
WO2010008582A2
(en)
|
2008-07-18 |
2010-01-21 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell drug delivery system
|
EP2326351B1
(en)
|
2008-08-19 |
2017-12-27 |
Nektar Therapeutics |
Conjugates of small-interfering nucleic acids
|
EP2690175B1
(en)
|
2008-09-02 |
2016-12-28 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for combined inhibition of mutant EGFR gene and IL-6 expression
|
WO2011028218A1
(en)
|
2009-09-02 |
2011-03-10 |
Alnylam Pharmaceuticals, Inc. |
Process for triphosphate oligonucleotide synthesis
|
EP2165710A1
(en)
|
2008-09-19 |
2010-03-24 |
Institut Curie |
Tyrosine kinase receptor Tyro3 as a therapeutic target in the treatment of a bladder tumor
|
EP2949752B1
(en)
|
2008-09-22 |
2017-12-20 |
RXi Pharmaceuticals Corporation |
Reduced size self-delivering rnai compounds
|
EP3587434A1
(en)
|
2008-09-23 |
2020-01-01 |
Alnylam Pharmaceuticals Inc. |
Chemical modifications of monomers and oligonucleotides with click components for conjugation with ligands
|
CA2739170A1
(en)
|
2008-09-25 |
2010-04-01 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene
|
MX356687B
(es)
|
2008-09-29 |
2018-06-07 |
Monsanto Technology Llc |
Evento transgénico de frijol de soya mon87705 y métodos para detección del mismo.
|
US8591905B2
(en)
|
2008-10-12 |
2013-11-26 |
The Brigham And Women's Hospital, Inc. |
Nicotine immunonanotherapeutics
|
US8277812B2
(en)
|
2008-10-12 |
2012-10-02 |
Massachusetts Institute Of Technology |
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
|
US8343497B2
(en)
|
2008-10-12 |
2013-01-01 |
The Brigham And Women's Hospital, Inc. |
Targeting of antigen presenting cells with immunonanotherapeutics
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
WO2010045384A2
(en)
*
|
2008-10-15 |
2010-04-22 |
Somagenics Inc. |
Short hairpin rnas for inhibition of gene expression
|
CN103937793B
(zh)
|
2008-10-20 |
2017-08-11 |
阿尔尼拉姆医药品有限公司 |
抑制运甲状腺素蛋白表达的组合物和方法
|
US9289475B2
(en)
|
2008-11-06 |
2016-03-22 |
The Johns Hopkins University |
Treatment of chronic inflammatory respiratory disorders
|
EP3808177A1
(en)
|
2008-11-10 |
2021-04-21 |
Arbutus Biopharma Corporation |
Novel lipids and compositions for the delivery of therapeutics
|
US8735082B2
(en)
|
2008-11-10 |
2014-05-27 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Gene signature for predicting prognosis of patients with solid tumors
|
WO2010059226A2
(en)
|
2008-11-19 |
2010-05-27 |
Rxi Pharmaceuticals Corporation |
Inhibition of map4k4 through rnai
|
CN104673798B
(zh)
|
2008-12-03 |
2018-03-20 |
阿克丘勒斯治疗公司 |
UsiRNA复合物
|
WO2010065834A1
(en)
|
2008-12-04 |
2010-06-10 |
Opko Ophthalmics, Llc |
Compositions and methods for selective inhibition of pro-angiogenic vegf isoforms
|
EP3225281A1
(en)
|
2008-12-10 |
2017-10-04 |
Alnylam Pharmaceuticals, Inc. |
Gnaq targeted dsrna compositions and methods for inhibiting expression
|
EP2198879A1
(en)
|
2008-12-11 |
2010-06-23 |
Institut Curie |
CD74 modulator agent for regulating dendritic cell migration and device for studying the motility capacity of a cell
|
US20100233172A1
(en)
|
2008-12-16 |
2010-09-16 |
Bristol-Myers Squibb Company |
Methods of inhibiting quiescent tumor proliferation
|
WO2010080452A2
(en)
|
2008-12-18 |
2010-07-15 |
Quark Pharmaceuticals, Inc. |
siRNA COMPOUNDS AND METHODS OF USE THEREOF
|
EP2379076B1
(en)
|
2008-12-23 |
2014-11-12 |
The Trustees of Columbia University in the City of New York |
Phosphodiesterase inhibitors and uses thereof
|
WO2010074783A1
(en)
|
2008-12-23 |
2010-07-01 |
The Trustees Of Columbia University In The City Of New York |
Phosphodiesterase inhibitors and uses thereof
|
WO2010078536A1
(en)
|
2009-01-05 |
2010-07-08 |
Rxi Pharmaceuticals Corporation |
Inhibition of pcsk9 through rnai
|
US9745574B2
(en)
|
2009-02-04 |
2017-08-29 |
Rxi Pharmaceuticals Corporation |
RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
|
JP6066035B2
(ja)
*
|
2009-02-12 |
2017-01-25 |
クルナ・インコーポレーテッド |
グリア細胞由来神経栄養因子(gdnf)関連疾病の、gdnfに対する天然アンチセンス転写物の抑制による治療
|
CN101525388B
(zh)
*
|
2009-02-20 |
2012-02-01 |
中国人民解放军第四军医大学 |
特异性双链rna结合蛋白嵌合体及其在病毒感染性疾病中的应用
|
US20120041051A1
(en)
|
2009-02-26 |
2012-02-16 |
Kevin Fitzgerald |
Compositions And Methods For Inhibiting Expression Of MIG-12 Gene
|
CA2753975C
(en)
|
2009-03-02 |
2017-09-26 |
Alnylam Pharmaceuticals, Inc. |
Nucleic acid chemical modifications
|
US20100267806A1
(en)
|
2009-03-12 |
2010-10-21 |
David Bumcrot |
LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES
|
EP2408916A2
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
WO2010107957A2
(en)
|
2009-03-19 |
2010-09-23 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF GATA BINDING PROTEIN 3 (GATA3) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
CA2755773A1
(en)
|
2009-03-19 |
2010-09-23 |
Merck Sharp & Dohme Corp. |
Rna interference mediated inhibition of btb and cnc homology 1, basic leucine zipper transcription factor 1 (bach 1) gene expression using short interfering nucleic acid (sina)
|
EP2408458A1
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 (STAT6) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
EP2411019A2
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
WO2010111464A1
(en)
|
2009-03-27 |
2010-09-30 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
JP2012521762A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いた神経成長因子β鎖(NGFβ)遺伝子発現のRNA干渉媒介性阻害
|
SG174581A1
(en)
|
2009-03-27 |
2011-10-28 |
Merck Sharp & Dohme |
RNA INTERFERENCE MEDIATED INHIBITION OF THE INTERCELLULAR ADHESION MOLECULE 1 (ICAM-1)GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
EP2411520A2
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE THYMIC STROMAL LYMPHOPOIETIN (TSLP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
WO2010118243A2
(en)
|
2009-04-08 |
2010-10-14 |
Genentech, Inc. |
Use of il-27 antagonists to treat lupus
|
US8283332B2
(en)
|
2009-04-17 |
2012-10-09 |
University Of Louisville Research Foundation, Inc. |
PFKFB4 inhibitors and methods of using the same
|
EP2421976B1
(en)
|
2009-04-22 |
2015-09-16 |
BASF Plant Science Company GmbH |
Whole seed specific promoter
|
WO2010128465A1
(en)
|
2009-05-05 |
2010-11-11 |
Beeologics, Llc |
Prevention and treatment of nosema disease in bees
|
US9200276B2
(en)
|
2009-06-01 |
2015-12-01 |
Halo-Bio Rnai Therapeutics, Inc. |
Polynucleotides for multivalent RNA interference, compositions and methods of use thereof
|
EP2258858A1
(en)
|
2009-06-05 |
2010-12-08 |
Universitätsklinikum Freiburg |
Transgenic LSD1 animal model for cancer
|
PL3431076T3
(pl)
|
2009-06-10 |
2022-01-31 |
Arbutus Biopharma Corporation |
Ulepszona formulacja lipidowa
|
US9051567B2
(en)
|
2009-06-15 |
2015-06-09 |
Tekmira Pharmaceuticals Corporation |
Methods for increasing efficacy of lipid formulated siRNA
|
EP2266550A1
(en)
|
2009-06-15 |
2010-12-29 |
Institut Curie |
Antagonists of ß-catenin for preventing and/or treating neurodegenerative disorders
|
KR20120050429A
(ko)
|
2009-06-15 |
2012-05-18 |
알닐람 파마슈티칼스 인코포레이티드 |
Pcsk9 유전자를 표적으로 하는 지질 제형된 dsrna
|
WO2011003901A1
(en)
|
2009-07-10 |
2011-01-13 |
Basf Plant Science Company Gmbh |
Expression cassettes for endosperm-specific expression in plants
|
US8871730B2
(en)
|
2009-07-13 |
2014-10-28 |
Somagenics Inc. |
Chemical modification of short small hairpin RNAs for inhibition of gene expression
|
PL2453923T3
(pl)
|
2009-07-14 |
2016-06-30 |
Mayo Found Medical Education & Res |
Niekowalencyjne dostarczanie aktywnych czynników przez barierę krew-mózg przy udziale peptydów
|
SI2769737T1
(sl)
|
2009-07-20 |
2017-06-30 |
Bristol-Myers Squibb Company |
Kombinacija anti-ctla4 protitelesa z etoposidom za sinergistično zdravljenje proliferativnih bolezni
|
CN102481347A
(zh)
|
2009-07-24 |
2012-05-30 |
加州大学董事会 |
治疗和预防整合素αvβ5相关疾病的方法及组合物
|
US20110039789A1
(en)
*
|
2009-08-14 |
2011-02-17 |
Institut Curie |
Use of Huntingtin Protein for the Diagnosis and the Treatment of Cancer
|
WO2011020023A2
(en)
|
2009-08-14 |
2011-02-17 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated compositions and methods for inhibiting expression of a gene from the ebola virus
|
US8916693B2
(en)
|
2009-09-17 |
2014-12-23 |
Nektar Therapeutics |
Monoconjugated chitosans as delivery agents for small interfering nucleic acids
|
US20150025122A1
(en)
|
2009-10-12 |
2015-01-22 |
Larry J. Smith |
Methods and Compositions for Modulating Gene Expression Using Oligonucleotide Based Drugs Administered in vivo or in vitro
|
US8962584B2
(en)
|
2009-10-14 |
2015-02-24 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. |
Compositions for controlling Varroa mites in bees
|
CN102695798A
(zh)
|
2009-11-23 |
2012-09-26 |
水慷科技公司 |
母系诱导的动物不育
|
WO2011066475A1
(en)
|
2009-11-26 |
2011-06-03 |
Quark Pharmaceuticals, Inc. |
Sirna compounds comprising terminal substitutions
|
WO2011067712A1
(en)
|
2009-12-03 |
2011-06-09 |
Basf Plant Science Company Gmbh |
Expression cassettes for embryo-specific expression in plants
|
CA2783372C
(en)
|
2009-12-07 |
2019-07-16 |
Muthiah Manoharan |
Compositions for nucleic acid delivery
|
EP2509628B1
(en)
|
2009-12-07 |
2017-10-25 |
The Johns Hopkins University |
Sr-bi as a predictor of human female infertility and responsiveness to treatment
|
US8778904B2
(en)
|
2009-12-09 |
2014-07-15 |
Quark Pharmaceuticals, Inc. |
Methods and compositions for treating diseases, disorders or injury of the CNS
|
CN102741410B
(zh)
|
2009-12-09 |
2016-11-16 |
日东电工株式会社 |
Hsp47表达的调节
|
US10640457B2
(en)
|
2009-12-10 |
2020-05-05 |
The Trustees Of Columbia University In The City Of New York |
Histone acetyltransferase activators and uses thereof
|
ES2764999T3
(es)
|
2009-12-10 |
2020-06-05 |
Univ Columbia |
Activadores de histona acetiltransferasa y usos de los mismos
|
AU2010330814B2
(en)
|
2009-12-18 |
2017-01-12 |
Acuitas Therapeutics Inc. |
Methods and compositions for delivery of nucleic acids
|
US8293718B2
(en)
|
2009-12-18 |
2012-10-23 |
Novartis Ag |
Organic compositions to treat HSF1-related diseases
|
AU2010334911A1
(en)
|
2009-12-23 |
2012-07-12 |
Novartis Ag |
Lipids, lipid compositions, and methods of using them
|
WO2011084193A1
(en)
|
2010-01-07 |
2011-07-14 |
Quark Pharmaceuticals, Inc. |
Oligonucleotide compounds comprising non-nucleotide overhangs
|
CA2787994C
(en)
|
2010-01-26 |
2021-01-12 |
National Jewish Health |
Diagnosis and prognosis of idiopathic interstitial pneumonia by rs35705950 snp in muc5b gene promoter
|
WO2011100131A2
(en)
|
2010-01-28 |
2011-08-18 |
Alnylam Pharmacuticals, Inc. |
Monomers and oligonucleotides comprising cycloaddition adduct(s)
|
WO2011094580A2
(en)
|
2010-01-28 |
2011-08-04 |
Alnylam Pharmaceuticals, Inc. |
Chelated copper for use in the preparation of conjugated oligonucleotides
|
EP2534489A1
(en)
|
2010-02-10 |
2012-12-19 |
Novartis AG |
Methods and compounds for muscle growth
|
CN106074591B
(zh)
|
2010-03-24 |
2020-01-14 |
菲奥医药公司 |
眼部症候中的rna干扰
|
RU2615143C2
(ru)
|
2010-03-24 |
2017-04-04 |
Адвирна |
Самодоставляющие PHKi соединения уменьшенного размера
|
CN110042099A
(zh)
|
2010-03-24 |
2019-07-23 |
菲奥医药公司 |
皮肤与纤维化症候中的rna干扰
|
WO2011120953A1
(en)
|
2010-03-29 |
2011-10-06 |
Universite De Strasbourg |
Polymers for delivering molecules of interest
|
CA2792291A1
(en)
|
2010-03-29 |
2011-10-06 |
Kumamoto University |
Sirna therapy for transthyretin (ttr) related ocular amyloidosis
|
US9102938B2
(en)
|
2010-04-01 |
2015-08-11 |
Alnylam Pharmaceuticals, Inc. |
2′ and 5′ modified monomers and oligonucleotides
|
EP2555778A4
(en)
|
2010-04-06 |
2014-05-21 |
Alnylam Pharmaceuticals Inc |
COMPOSITIONS AND METHODS FOR INHIBITING CD274 / PD-L1 GENE EXPRESSION
|
US10913767B2
(en)
|
2010-04-22 |
2021-02-09 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising acyclic and abasic nucleosides and analogs
|
WO2011133868A2
(en)
|
2010-04-22 |
2011-10-27 |
Alnylam Pharmaceuticals, Inc. |
Conformationally restricted dinucleotide monomers and oligonucleotides
|
WO2011133871A2
(en)
|
2010-04-22 |
2011-10-27 |
Alnylam Pharmaceuticals, Inc. |
5'-end derivatives
|
WO2011133931A1
(en)
|
2010-04-22 |
2011-10-27 |
Genentech, Inc. |
Use of il-27 antagonists for treating inflammatory bowel disease
|
WO2011131707A1
(en)
|
2010-04-23 |
2011-10-27 |
Novartis Ag |
ORGANIC COMPOSITIONS TO TREAT BETA-ENaC-RELATED DISEASES
|
KR101223660B1
(ko)
|
2010-05-20 |
2013-01-17 |
광주과학기술원 |
HIF-2α 억제제를 유효성분으로 포함하는 관절염 예방 또는 치료용 약제학적 조성물
|
EP2571987B1
(en)
|
2010-05-21 |
2017-03-01 |
Peptimed, Inc. |
Reagents for treating cancer
|
CN107080839A
(zh)
|
2010-05-26 |
2017-08-22 |
西莱克塔生物科技公司 |
多价的合成纳米载体疫苗
|
US20130149320A1
(en)
|
2010-05-31 |
2013-06-13 |
Centre National De La Recherche Scientifique |
Asf1b as a Prognosis Marker and Therapeutic Target in Human Cancer
|
CA3102008A1
(en)
|
2010-06-02 |
2011-12-08 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods directed to treating liver fibrosis
|
US20130236968A1
(en)
|
2010-06-21 |
2013-09-12 |
Alnylam Pharmaceuticals, Inc. |
Multifunctional copolymers for nucleic acid delivery
|
WO2011163466A1
(en)
|
2010-06-23 |
2011-12-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Regulation of skin pigmentation by neuregulin-1 (nrg-1)
|
WO2012016188A2
(en)
|
2010-07-30 |
2012-02-02 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
WO2012016184A2
(en)
|
2010-07-30 |
2012-02-02 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
US8518907B2
(en)
|
2010-08-02 |
2013-08-27 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
|
EP2606134B1
(en)
|
2010-08-17 |
2019-04-10 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS B VIRUS (HBV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US9243246B2
(en)
|
2010-08-24 |
2016-01-26 |
Sirna Therapeutics, Inc. |
Single-stranded RNAi agents containing an internal, non-nucleic acid spacer
|
EP2609106A4
(en)
|
2010-08-26 |
2014-03-19 |
Merck Sharp & Dohme |
RNA INTERFERENCE-MEDIATED INHIBITION OF EXPRESSION OF PHD2 GENE (PROLYL HYDROXYLASE DOMAIN 2) USING SMALL INTERFERING NUCLEIC ACID (PANI)
|
EP2433644A1
(en)
|
2010-09-22 |
2012-03-28 |
IMBA-Institut für Molekulare Biotechnologie GmbH |
Breast cancer therapeutics
|
US20140134231A1
(en)
|
2010-10-11 |
2014-05-15 |
Sanford-Burnham Medical Research Institute |
Mir-211 expression and related pathways in human melanoma
|
AR083445A1
(es)
|
2010-10-14 |
2013-02-27 |
Univ Mie |
siARN CONTRA LA FIBROSIS
|
WO2012051567A2
(en)
|
2010-10-15 |
2012-04-19 |
The Trustees Of Columbia University In The City Of New York |
Obesity-related genes and their proteins and uses thereof
|
EP3766975A1
(en)
|
2010-10-29 |
2021-01-20 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of gene expression using short interfering nucleic acid (sina)
|
WO2012061443A2
(en)
|
2010-11-01 |
2012-05-10 |
NanoOncology, Inc. |
Compositions of a peptide-based system for cell-specific targeting
|
JP5948337B2
(ja)
|
2010-11-02 |
2016-07-06 |
ザ トラスティース オブ コロンビア ユニバーシティ インザ シティ オブ ニューヨーク |
脱毛症の治療方法
|
US9198911B2
(en)
|
2010-11-02 |
2015-12-01 |
The Trustees Of Columbia University In The City Of New York |
Methods for treating hair loss disorders
|
US9339513B2
(en)
|
2010-11-09 |
2016-05-17 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated compositions and methods for inhibiting expression of Eg5 and VEGF genes
|
EP2455456A1
(en)
|
2010-11-22 |
2012-05-23 |
Institut Curie |
Use of kinesin inhibitors in HIV infection treatment and a method for screening them
|
AU2011338682B2
(en)
|
2010-12-06 |
2017-04-27 |
Quark Pharmaceuticals, Inc. |
Double stranded oligonucleotide compounds comprising threose modifications
|
US9150926B2
(en)
|
2010-12-06 |
2015-10-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Diagnosis and treatment of adrenocortical tumors using human microRNA-483
|
US10202615B2
(en)
|
2010-12-10 |
2019-02-12 |
Vanderbilt University |
Mammalian genes involved in toxicity and infection
|
ES2820863T3
(es)
|
2010-12-22 |
2021-04-22 |
Univ Columbia |
Moduladores de histona acetiltransferasa y usos de los mismos
|
US20140056811A1
(en)
|
2010-12-27 |
2014-02-27 |
Compugen Ltd. |
New cell-penetrating peptides and uses thereof
|
EP3202760B1
(en)
|
2011-01-11 |
2019-08-21 |
Alnylam Pharmaceuticals, Inc. |
Pegylated lipids and their use for drug delivery
|
SG10201604479YA
(en)
|
2011-03-03 |
2016-07-28 |
Quark Pharmaceuticals Inc |
Oligonucleotide Modulators Of The Toll-Like Receptor Pathway
|
AU2012223365B2
(en)
|
2011-03-03 |
2016-11-10 |
Quark Pharmaceuticals, Inc. |
Compositions and methods for treating lung disease and injury
|
US9796979B2
(en)
|
2011-03-03 |
2017-10-24 |
Quark Pharmaceuticals Inc. |
Oligonucleotide modulators of the toll-like receptor pathway
|
WO2012119764A1
(en)
|
2011-03-08 |
2012-09-13 |
Società Bulloneria Europea S.B.E. Spa |
A high load flanged fastener to be installed by tensioning tools
|
JP2014515012A
(ja)
|
2011-03-15 |
2014-06-26 |
ユニヴァーシティー オブ ユタ リサーチ ファウンデーション |
血管関連黄斑症およびその症状の診断および治療方法
|
KR101291668B1
(ko)
|
2011-04-21 |
2013-08-01 |
서울대학교산학협력단 |
미코박테리아―대장균용 셔틀 벡터 및 이의 용도
|
US10196637B2
(en)
|
2011-06-08 |
2019-02-05 |
Nitto Denko Corporation |
Retinoid-lipid drug carrier
|
TWI658830B
(zh)
|
2011-06-08 |
2019-05-11 |
日東電工股份有限公司 |
Hsp47表現調控強化用類視色素脂質體
|
WO2012177949A2
(en)
|
2011-06-21 |
2012-12-27 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibition of expression of protein c (proc) genes
|
KR102540778B1
(ko)
|
2011-06-21 |
2023-06-07 |
알닐람 파마슈티칼스 인코포레이티드 |
아포리포단백질 c-iii(apoc3) 유전자의 발현 억제를 위한 조성물 및 방법
|
WO2012177906A1
(en)
|
2011-06-21 |
2012-12-27 |
Alnylam Pharmaceuticals, Inc. |
Assays and methods for determining activity of a therapeutic agent in a subject
|
WO2012177921A2
(en)
|
2011-06-21 |
2012-12-27 |
Alnylam Pharmaceuticals, Inc |
Compositions and methods for inhibiting hepcidin antimicrobial peptide (hamp) or hamp-related gene expression
|
WO2012178033A2
(en)
|
2011-06-23 |
2012-12-27 |
Alnylam Pharmaceuticals, Inc. |
Serpina1 sirnas: compositions of matter and methods of treatment
|
WO2013003697A1
(en)
|
2011-06-30 |
2013-01-03 |
Trustees Of Boston University |
Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1)
|
AU2012301617A1
(en)
|
2011-09-02 |
2014-04-17 |
Salk Institute For Biological Studies |
CaMKII, IP3R, calcineurin, p38 and MK2/3 inhibitors to treat metabolic disturbances of obesity
|
CA2847283C
(en)
|
2011-09-02 |
2023-03-14 |
Novartis Ag |
Organic compositions to treat hsf1-related diseases
|
WO2013040251A2
(en)
|
2011-09-13 |
2013-03-21 |
Asurgen, Inc. |
Methods and compositions involving mir-135b for distinguishing pancreatic cancer from benign pancreatic disease
|
US9352312B2
(en)
|
2011-09-23 |
2016-05-31 |
Alere Switzerland Gmbh |
System and apparatus for reactions
|
CA2849476A1
(en)
|
2011-09-27 |
2013-04-04 |
Alnylam Pharmaceuticals, Inc. |
Di-aliphatic substituted pegylated lipids
|
CN108373506A
(zh)
|
2011-10-14 |
2018-08-07 |
霍夫曼-拉罗奇有限公司 |
抗HtrA1抗体及使用方法
|
AU2012325997C1
(en)
|
2011-10-18 |
2018-07-05 |
Dicerna Pharmaceuticals, Inc. |
Amine cationic lipids and uses thereof
|
EP2773758B1
(en)
|
2011-11-03 |
2017-06-07 |
Quark Pharmaceuticals, Inc. |
Compositions for use in neuroprotection
|
EP2776565A1
(en)
|
2011-11-08 |
2014-09-17 |
Quark Pharmaceuticals, Inc. |
Methods and compositions for treating diseases, disorders or injury of the nervous system
|
US10023862B2
(en)
|
2012-01-09 |
2018-07-17 |
Arrowhead Pharmaceuticals, Inc. |
Organic compositions to treat beta-catenin-related diseases
|
KR101371696B1
(ko)
|
2012-02-02 |
2014-03-07 |
세종대학교산학협력단 |
벼도열병 발병인자의 스크리닝 방법
|
CN107982548A
(zh)
|
2012-02-07 |
2018-05-04 |
全球生物疗法有限公司 |
核酸输送的区室化方法及其组合物和应用
|
JP6212107B2
(ja)
|
2012-03-29 |
2017-10-11 |
ザ トラスティース オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク |
脱毛障害を処置するための方法
|
WO2013165816A2
(en)
|
2012-05-02 |
2013-11-07 |
Merck Sharp & Dohme Corp. |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
|
EP2844757A2
(en)
|
2012-05-02 |
2015-03-11 |
Novartis AG |
Organic compositions to treat kras-related diseases
|
US9133515B2
(en)
|
2012-05-16 |
2015-09-15 |
Silence Therapeutics Gmbh |
Use of VEGFR1 as a biomarker
|
WO2013187556A1
(en)
|
2012-06-14 |
2013-12-19 |
Scripps Korea Antibody Institute |
Novel antibody specific for clec14a and uses thereof
|
US9726661B2
(en)
|
2012-07-06 |
2017-08-08 |
Institut Gustave-Roussy |
Simultaneous detection of cannibalism and senescence as prognostic marker for cancer
|
EP2877494B1
(en)
|
2012-07-23 |
2020-07-15 |
La Jolla Institute for Allergy and Immunology |
Ptprs and proteoglycans in autoimmune disease
|
WO2014018375A1
(en)
|
2012-07-23 |
2014-01-30 |
Xenon Pharmaceuticals Inc. |
Cyp8b1 and uses thereof in therapeutic and diagnostic methods
|
EP2700949A1
(en)
|
2012-08-24 |
2014-02-26 |
IMG Institut für medizinische Genomforschung Planungsgesellschaft M.B.H. |
Use of biliverdin reductase proteins as cancer marker
|
EP3677310A1
(en)
|
2012-10-08 |
2020-07-08 |
St. Jude Children's Research Hospital |
Therapies based on control of regulatory t cell stability and function via a neuropilin-1:semaphorin axis
|
WO2014068072A1
(en)
|
2012-10-31 |
2014-05-08 |
Institut Gustave-Roussy |
Identification, assessment and therapy of essential thrombocythemia with resistance to jak2 inhibitors
|
SG11201506805QA
(en)
|
2013-02-28 |
2015-09-29 |
Arrowhead Res Corp |
Organic compositions to treat epas1-related diseases
|
WO2014135655A1
(en)
|
2013-03-06 |
2014-09-12 |
Institut Curie |
Compositions and methods for treating muscle-invasive bladder cancer
|
EP3608308B1
(en)
|
2013-03-08 |
2021-07-21 |
Novartis AG |
Lipids and lipid compositions for the delivery of active agents
|
MX360560B
(es)
|
2013-03-13 |
2018-11-07 |
Geneweave Biosciences Inc |
Partículas de transducción no replicativas y sistemas indicadores a base de partículas de transducción.
|
CA2907152A1
(en)
|
2013-03-15 |
2014-09-25 |
The Trustees Of Columbia University In The City Of New York |
Fusion proteins and methods thereof
|
AU2014233198B2
(en)
|
2013-03-15 |
2019-06-27 |
Sutter West Bay Hospitals |
Falz for use as a target for therapies to treat cancer
|
US9937231B2
(en)
|
2013-03-27 |
2018-04-10 |
The General Hospital Corporation |
Methods and agents for treating Alzheimer's disease
|
JP6896420B2
(ja)
|
2013-07-03 |
2021-06-30 |
シティ・オブ・ホープCity of Hope |
抗癌組成物
|
BR112016000395B1
(pt)
|
2013-07-10 |
2022-12-06 |
Basf Se |
Molécula de dsrna, sequência de dna, métodos para controlar um fitopatógeno e composição para controlar um fitopatógeno
|
BR112016000555B1
(pt)
|
2013-07-19 |
2022-12-27 |
Monsanto Technology Llc |
Método para controlar uma infestação da espécie de leptinotarsa em uma planta, composição inseticida e construção de dna recombinante
|
US9889200B2
(en)
|
2013-07-31 |
2018-02-13 |
Qbi Enterprises Ltd. |
Sphingolipid-polyalkylamine-oligonucleotide compounds
|
EP3027223A1
(en)
|
2013-07-31 |
2016-06-08 |
QBI Enterprises Ltd. |
Methods of use of sphingolipid polyalkylamine oligonucleotide compounds
|
ES2647789T3
(es)
|
2013-08-08 |
2017-12-26 |
Global Bio Therapeutics, Inc. |
Dispositivo de inyección para procedimientos mínimamente invasivos
|
CA2920261C
(en)
|
2013-08-08 |
2018-04-03 |
Global Bio Therapeutics, Inc. |
Clamp device for minimally invasive procedures and uses thereof
|
EP3052107B1
(en)
|
2013-10-04 |
2018-05-02 |
Novartis AG |
Organic compounds to treat hepatitis b virus
|
WO2015051135A2
(en)
|
2013-10-04 |
2015-04-09 |
Novartis Ag |
Organic compositions to treat hepcidin-related diseases
|
WO2015051044A2
(en)
|
2013-10-04 |
2015-04-09 |
Novartis Ag |
Novel formats for organic compounds for use in rna interference
|
US9988627B2
(en)
|
2013-10-04 |
2018-06-05 |
Novartis Ag |
Formats for organic compounds for use in RNA interference
|
WO2015051045A2
(en)
|
2013-10-04 |
2015-04-09 |
Novartis Ag |
3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE
|
EP3055426B1
(en)
|
2013-10-09 |
2019-06-19 |
The United States of America as represented by The Secretary Department of Health and Human Services |
Detection of hepatitis delta virus (hdv) for the diagnosis and treatment of sjögren's syndrome and lymphoma
|
CA2926084A1
(en)
|
2013-10-11 |
2015-04-16 |
Genentech, Inc. |
Nsp4 inhibitors and methods of use
|
AU2014346457A1
(en)
|
2013-11-11 |
2016-06-02 |
Sirna Therapeutics, Inc. |
Systemic delivery of myostatin short interfering nucleic acids (siNA) conjugated to a lipophilic moiety
|
CN106061488B
(zh)
|
2013-12-02 |
2021-04-09 |
菲奥医药公司 |
癌症的免疫治疗
|
EP4019506A1
(en)
|
2013-12-19 |
2022-06-29 |
Novartis AG |
Lipids and lipid compositions for the delivery of active agents
|
WO2015095340A1
(en)
|
2013-12-19 |
2015-06-25 |
Novartis Ag |
Lipids and lipid compositions for the delivery of active agents
|
US9682123B2
(en)
|
2013-12-20 |
2017-06-20 |
The Trustees Of Columbia University In The City Of New York |
Methods of treating metabolic disease
|
US9274117B2
(en)
|
2013-12-21 |
2016-03-01 |
Catholic University Industry Academic |
Use of SIRT7 as novel cancer therapy target and method for treating cancer using the same
|
WO2015098113A1
(ja)
|
2013-12-27 |
2015-07-02 |
独立行政法人医薬基盤研究所 |
悪性腫瘍の治療薬
|
WO2015118167A1
(en)
|
2014-02-10 |
2015-08-13 |
Institut Curie |
Use of mcoln-1 modulators to regulate cell migration
|
PT3116902T
(pt)
|
2014-03-11 |
2020-04-03 |
Cellectis |
Método para gerar células t compatíveis para transplante alogénico
|
JP6771387B2
(ja)
|
2014-03-25 |
2020-10-21 |
アークトゥラス・セラピューティクス・インコーポレイテッドArcturus Therapeutics,Inc. |
遺伝子サイレンシング用トランスサイレチン対立遺伝子選択的unaオリゴマー
|
US9856475B2
(en)
|
2014-03-25 |
2018-01-02 |
Arcturus Therapeutics, Inc. |
Formulations for treating amyloidosis
|
AU2015236215B2
(en)
|
2014-03-25 |
2020-03-19 |
Arcturus Therapeutics, Inc. |
UNA oligomers having reduced off-target effects in gene silencing
|
CA2943405A1
(en)
|
2014-03-31 |
2015-10-08 |
Debiopharm International Sa |
Fgfr fusions
|
US11091770B2
(en)
|
2014-04-01 |
2021-08-17 |
Monsanto Technology Llc |
Compositions and methods for controlling insect pests
|
US11279934B2
(en)
|
2014-04-28 |
2022-03-22 |
Phio Pharmaceuticals Corp. |
Methods for treating cancer using nucleic acids targeting MDM2 or MYCN
|
KR101633881B1
(ko)
|
2014-05-08 |
2016-06-28 |
고려대학교 산학협력단 |
도파민 의존성 신경장애 치료를 위한 REV-ERBα 유전자의 용도
|
KR101633876B1
(ko)
|
2014-05-08 |
2016-06-28 |
고려대학교 산학협력단 |
정서장애 및 중독질환 치료를 위한 REV-ERBα 유전자의 용도
|
WO2016011123A1
(en)
|
2014-07-16 |
2016-01-21 |
Arrowhead Research Corporation |
Organic compositions to treat apoc3-related diseases
|
WO2016010840A1
(en)
|
2014-07-16 |
2016-01-21 |
Novartis Ag |
Method of encapsulating a nucleic acid in a lipid nanoparticle host
|
US10378012B2
(en)
|
2014-07-29 |
2019-08-13 |
Monsanto Technology Llc |
Compositions and methods for controlling insect pests
|
JP6968696B2
(ja)
|
2014-08-22 |
2021-11-17 |
インファン・リウ |
異常なレベル及び/又は活性のifp35ファミリーのタンパク質に関連する疾患又は障害を治療及び/又は予防するための方法及び組成物
|
ES2969956T3
(es)
|
2014-09-05 |
2024-05-23 |
Novartis Ag |
Lípidos y composiciones lipídicas para el suministro de agentes activos
|
US10900039B2
(en)
|
2014-09-05 |
2021-01-26 |
Phio Pharmaceuticals Corp. |
Methods for treating aging and skin disorders using nucleic acids targeting Tyr or MMP1
|
JP6841753B2
(ja)
|
2014-09-15 |
2021-03-10 |
ザ チルドレンズ メディカル センター コーポレーション |
ヒストンh3−リジントリメチル化を除去することによって体細胞核移入(scnt)効率を増加させるための方法および組成物
|
CA2962406A1
(en)
|
2014-09-25 |
2016-03-31 |
Cold Spring Harbor Laboratory |
Treatment of rett syndrome
|
US20170304459A1
(en)
|
2014-10-10 |
2017-10-26 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for inhalation delivery of conjugated oligonucleotide
|
AU2015346281B2
(en)
|
2014-11-12 |
2021-12-02 |
Nmc, Inc. |
Transgenic plants with engineered redox sensitive modulation of photosynthetic antenna complex pigments and methods for making the same
|
EP3925979A3
(en)
|
2014-12-23 |
2022-03-23 |
The Trustees of Columbia University in the City of New York |
Fgfr-tacc fusion proteins and methods thereof
|
US10264976B2
(en)
|
2014-12-26 |
2019-04-23 |
The University Of Akron |
Biocompatible flavonoid compounds for organelle and cell imaging
|
CN108064288B
(zh)
|
2015-01-22 |
2021-11-26 |
孟山都技术公司 |
用于控制叶甲属的组合物和方法
|
AU2016226414B2
(en)
|
2015-03-02 |
2021-09-09 |
180 Therapeutics Lp |
Method of treating a localized fibrotic disorder using an IL-33 antagonist
|
CN107429251A
(zh)
|
2015-03-09 |
2017-12-01 |
肯塔基大学研究基金会 |
用于治疗乳腺癌的miRNA
|
WO2016145003A1
(en)
|
2015-03-09 |
2016-09-15 |
University Of Kentucky Research Foundation |
Rna nanoparticle for treatment of gastric cancer
|
US10584144B2
(en)
|
2015-03-09 |
2020-03-10 |
University Of Kentucky Research Foundation |
RNA nanoparticles for brain tumor treatment
|
KR101797569B1
(ko)
|
2015-03-18 |
2017-11-22 |
한국교통대학교산학협력단 |
금속 나노입자 기반 간 표적성 핵산 전달체 및 이의 제조방법
|
US10519447B2
(en)
|
2015-04-01 |
2019-12-31 |
Arcturus Therapeutics, Inc. |
Therapeutic UNA oligomers and uses thereof
|
US11279768B1
(en)
|
2015-04-03 |
2022-03-22 |
Precision Biologics, Inc. |
Anti-cancer antibodies, combination therapies, and uses thereof
|
CN107614685B
(zh)
|
2015-04-17 |
2021-10-19 |
肯塔基大学研究基金会 |
Rna纳米颗粒及其使用方法
|
WO2016176617A2
(en)
|
2015-04-29 |
2016-11-03 |
New York University |
Method for treating high-grade gliomas
|
CN116063499A
(zh)
|
2015-06-12 |
2023-05-05 |
艾利妥 |
抗cd33抗体及其使用方法
|
JP7497953B2
(ja)
|
2015-06-12 |
2024-06-11 |
アレクトル エルエルシー |
抗cd33抗体及びその使用方法
|
US10669528B2
(en)
|
2015-06-25 |
2020-06-02 |
Children's Medical Center Corporation |
Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance
|
EP3862005A1
(en)
|
2015-07-06 |
2021-08-11 |
Phio Pharmaceuticals Corp. |
Nucleic acid molecules targeting superoxide dismutase 1 (sod1)
|
WO2017007825A1
(en)
|
2015-07-06 |
2017-01-12 |
Rxi Pharmaceuticals Corporation |
Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach
|
WO2017013270A1
(en)
|
2015-07-23 |
2017-01-26 |
Universite De Strasbourg |
Use of leptin signaling inhibitor for protecting kidneys from patients having ciliopathy
|
WO2017015671A1
(en)
|
2015-07-23 |
2017-01-26 |
Arcturus Therapeutics, Inc. |
Compositions for treating amyloidosis
|
CA2995995A1
(en)
|
2015-08-24 |
2017-03-02 |
Halo-Bio Rnai Therapeutics, Inc. |
Polynucleotide nanoparticles for the modulation of gene expression and uses thereof
|
US10072065B2
(en)
|
2015-08-24 |
2018-09-11 |
Mayo Foundation For Medical Education And Research |
Peptide-mediated delivery of immunoglobulins across the blood-brain barrier
|
CN108137702B
(zh)
|
2015-08-28 |
2023-01-06 |
艾利妥 |
抗siglec-7抗体及其使用方法
|
KR20180051550A
(ko)
|
2015-09-02 |
2018-05-16 |
알닐람 파마슈티칼스 인코포레이티드 |
프로그램된 세포사 1 리간드 1 (PD-L1) iRNA 조성물 및 그의 사용 방법
|
EP3347486A4
(en)
|
2015-09-09 |
2019-06-19 |
The Trustees of Columbia University in the City of New York |
REDUCTION OF ER-MAM-LOCALIZED APP-C99 AND METHOD FOR THE TREATMENT OF ALZHEIMER DISEASE
|
WO2017059113A1
(en)
|
2015-09-29 |
2017-04-06 |
Duke University |
Compositions and methods for identifying and treating dystonia disorders
|
EP4435105A2
(en)
|
2015-09-29 |
2024-09-25 |
Amgen Inc. |
Asgr inhibitors for reduzing cholesterol levels
|
EP3365446A4
(en)
|
2015-10-19 |
2019-06-26 |
Phio Pharmaceuticals Corp. |
SELF ADMINISTRATION-REDUCED SIZE NUCLEIC ACID COMPOUNDS TARGETING LONGS NON-CODING LONGS
|
JP7060502B2
(ja)
|
2015-10-29 |
2022-04-26 |
アレクトル エルエルシー |
抗Siglec-9抗体及びその使用方法
|
WO2017075212A1
(en)
|
2015-10-30 |
2017-05-04 |
Genentech, Inc. |
Anti-htra1 antibodies and methods of use thereof
|
CA3005937C
(en)
|
2015-12-13 |
2021-11-09 |
Nitto Denko Corporation |
Sirna structures for high activity and reduced off target
|
US11072777B2
(en)
|
2016-03-04 |
2021-07-27 |
University Of Louisville Research Foundation, Inc. |
Methods and compositions for ex vivo expansion of very small embryonic-like stem cells (VSELs)
|
US20190119642A1
(en)
|
2016-03-15 |
2019-04-25 |
Children's Medical Center Corporation |
Methods and compositions relating to hematopoietic stem cell expansion
|
US10883108B2
(en)
|
2016-03-31 |
2021-01-05 |
The Schepens Eye Research Institute, Inc. |
Endomucin inhibitor as an anti-angiogenic agent
|
MA45328A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Compositions acide nucléique-polypeptide et utilisations de celles-ci
|
MA45470A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques kras et leurs utilisations
|
MA45469A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques de bêta-caténine et leurs utilisations
|
MA45349A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques egfr et leurs utilisations
|
RU2725286C2
(ru)
|
2016-05-13 |
2020-06-30 |
4Д Молекьюлар Терапьютикс Инк. |
Варианты капсидов аденоассоциированного вируса и способы их применения
|
WO2018020012A1
(en)
|
2016-07-29 |
2018-02-01 |
Danmarks Tekniske Universitet |
Methods for decoupling cell growth from production of biochemicals and recombinant polypeptides
|
EP3516062A1
(en)
|
2016-09-21 |
2019-07-31 |
Alnylam Pharmaceuticals, Inc. |
Myostatin irna compositions and methods of use thereof
|
JP2019535839A
(ja)
|
2016-11-29 |
2019-12-12 |
ピュアテック ヘルス エルエルシー |
治療剤の送達のためのエクソソーム
|
US11147249B2
(en)
|
2016-12-08 |
2021-10-19 |
Alector Llc |
Siglec transgenic mice and methods of use thereof
|
US10894837B2
(en)
|
2016-12-16 |
2021-01-19 |
Université De Bordeaux |
MMP9 inhibitors and uses thereof in the prevention or treatment of a depigmenting disorder
|
US11359014B2
(en)
|
2017-05-16 |
2022-06-14 |
Alector Llc |
Anti-siglec-5 antibodies and methods of use thereof
|
EP3624841A4
(en)
|
2017-06-15 |
2021-01-27 |
Cancer Advances, Inc., |
COMPOSITIONS AND METHODS OF INDUCING HUMORAL AND CELLULAR IMMUNITIES AGAINST TUMORS AND CANCER
|
US20200199541A1
(en)
|
2017-06-16 |
2020-06-25 |
Imba - Institut Für Molekulare Biotechnologie Gmbh |
Blood vessel organoid, methods of producing and using said organoids
|
WO2019028283A1
(en)
|
2017-08-03 |
2019-02-07 |
Alector Llc |
ANTI-CD33 ANTIBODIES AND METHODS OF USE
|
CN111433360B
(zh)
|
2017-09-07 |
2024-01-12 |
北京泰德制药股份有限公司 |
靶向ckip-1的双链rna分子及其用途
|
CR20200108A
(es)
|
2017-09-11 |
2020-06-28 |
Arrowhead Pharmaceuticals Inc |
Rnai agents and compositions for inhibiting expression of apolipoprotein c-iii (apoc3)
|
BR112020005436B1
(pt)
|
2017-09-20 |
2022-08-02 |
4D Molecular Therapeutics Inc |
Proteína do capsídeo de variante do vírus adenoassociado, virion do aav recombinante (raav) infeccioso, composições, composições farmacêuticas e usos de virion de raav ou de composições farmacêuticas
|
PT3717636T
(pt)
|
2017-11-27 |
2023-05-30 |
4D Molecular Therapeutics Inc |
Cápsides variantes de vírus adeno-associado e utilização para inibir a angiogénese
|
MX2020005860A
(es)
|
2017-12-06 |
2020-09-09 |
Avidity Biosciences Inc |
Composiciones y metodos de tratamiento de atrofia muscular y distrofia miotonica.
|
US11470827B2
(en)
|
2017-12-12 |
2022-10-18 |
Alector Llc |
Transgenic mice expressing human TREM proteins and methods of use thereof
|
AU2018392782B2
(en)
|
2017-12-21 |
2023-08-31 |
Alnylam Pharmaceuticals, Inc. |
Chirally-enriched double-stranded RNA agents
|
US20210162007A1
(en)
|
2018-04-09 |
2021-06-03 |
President And Fellows Of Harvard College |
Modulating nuclear receptors and methods of using same
|
JP7512207B2
(ja)
|
2018-05-24 |
2024-07-08 |
サーナオミクス インコーポレイテッド |
核酸治療薬のための調節可能な共カップリングポリペプチドナノ粒子送達系の組成物および方法
|
MA53328A
(fr)
|
2018-07-27 |
2021-06-09 |
Alector Llc |
Anticorps anti-siglec-5 et leurs procédés d'utilisation
|
JP2022501388A
(ja)
|
2018-09-19 |
2022-01-06 |
ラホヤ インスティチュート フォー イミュノロジー |
関節リウマチにおけるptprs及びプロテオグリカン
|
US11708575B2
(en)
|
2018-11-16 |
2023-07-25 |
Nitto Denko Corporation |
RNA interference delivery formulation and methods for malignant tumors
|
JP2022546040A
(ja)
|
2019-08-27 |
2022-11-02 |
サノフイ |
Pcsk9を阻害するための組成物および方法
|
KR102100163B1
(ko)
|
2019-09-24 |
2020-04-13 |
테고사이언스 (주) |
켈로이드 또는 비후성 반흔 예방 또는 치료용 조성물
|
CR20220278A
(es)
|
2019-12-18 |
2022-07-01 |
Novartis Ag |
Derivados de 3-(5-metoxi-1-oxoisoindolin-2-il)piperidin-2,6-diona y usos de los mismos
|
CN115176005A
(zh)
|
2019-12-18 |
2022-10-11 |
诺华股份有限公司 |
用于治疗血红蛋白病的组合物和方法
|
US20210253685A1
(en)
|
2020-01-08 |
2021-08-19 |
Regeneron Pharmaceuticals, Inc. |
Treatment of fibrodysplasia ossificans progressiva
|
WO2021150300A1
(en)
|
2020-01-22 |
2021-07-29 |
Massachusetts Institute Of Technology |
Inducible tissue constructs and uses thereof
|
US11642407B2
(en)
|
2020-02-28 |
2023-05-09 |
Massachusetts Institute Of Technology |
Identification of variable influenza residues and uses thereof
|
CA3172111A1
(en)
|
2020-03-19 |
2021-09-23 |
Barbora MALECOVA |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
WO2022147481A1
(en)
|
2020-12-30 |
2022-07-07 |
Ansun Biopharma Inc. |
Combination therapy of an oncolytic virus delivering a foreign antigen and an engineered immune cell expressing a chimeric receptor targeting the foreign antigen
|
JP2024519888A
(ja)
|
2021-05-28 |
2024-05-21 |
上海瑞宏迪医薬有限公司 |
カプシド変異を有する組換えアデノ随伴ウイルス及びその応用
|
EP4359527A2
(en)
|
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Novartis AG |
Compositions and methods for the treatment of hemoglobinopathies
|
WO2023012165A1
(en)
|
2021-08-02 |
2023-02-09 |
Universite De Montpellier |
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|
KR20240099259A
(ko)
|
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아스널 바이오사이언시스, 인크. |
공동 발현된 shrna 및 논리 게이트 시스템을 갖는 면역 세포
|
TW202417626A
(zh)
|
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具有共表現的tgfbr shrna之免疫細胞
|
WO2024059824A2
(en)
|
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Arsenal Biosciences, Inc. |
Immune cells with combination gene perturbations
|
WO2024186656A1
(en)
|
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Arsenal Biosciences, Inc. |
Systems targeting psma and ca9
|