ES2570665T3 - Factor de permisividad celular para virus, y usos del mismo - Google Patents

Factor de permisividad celular para virus, y usos del mismo

Info

Publication number
ES2570665T3
ES2570665T3 ES12178283T ES12178283T ES2570665T3 ES 2570665 T3 ES2570665 T3 ES 2570665T3 ES 12178283 T ES12178283 T ES 12178283T ES 12178283 T ES12178283 T ES 12178283T ES 2570665 T3 ES2570665 T3 ES 2570665T3
Authority
ES
Spain
Prior art keywords
viruses
factor
polypeptide
permissiveness
cellular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12178283T
Other languages
English (en)
Inventor
Jay Gregory Calvert
Shelly Lynn Shields
David Ewell Slade
Siao-Kun Wan Welch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zoetis Services LLC
Original Assignee
Zoetis Services LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services LLC filed Critical Zoetis Services LLC
Application granted granted Critical
Publication of ES2570665T3 publication Critical patent/ES2570665T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C12N5/0686—Kidney cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0688—Cells from the lungs or the respiratory tract
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/12011—Asfarviridae
    • C12N2710/12051—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10051—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Un procedimiento in vitro para facilitar la infección de una célula de vertebrado por el VSRRP que comprende la etapa de (a) dirigir la expresión aumentada de un polipéptido de CD163 por dicha célula de vertebrado en el que dicho polipéptido de CD163 comprende un dominio transmembrana y dicho polipéptido de CD163 tiene (i) una identidad de al menos el 70 % con la SEQ ID NO: 2 o (ii) una identidad de al menos el 99 % con un polipéptido expuesto en la SEQ ID NO: 14 y en el que dicha expresión aumentada se logra mediante la introducción de ácido nucleico exógeno.
ES12178283T 2004-04-23 2005-04-05 Factor de permisividad celular para virus, y usos del mismo Active ES2570665T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56521404P 2004-04-23 2004-04-23
US63473604P 2004-12-09 2004-12-09

Publications (1)

Publication Number Publication Date
ES2570665T3 true ES2570665T3 (es) 2016-05-19

Family

ID=35320736

Family Applications (2)

Application Number Title Priority Date Filing Date
ES05736317T Active ES2530694T3 (es) 2004-04-23 2005-04-05 Factor de permisividad celular para virus, y usos del mismo
ES12178283T Active ES2570665T3 (es) 2004-04-23 2005-04-05 Factor de permisividad celular para virus, y usos del mismo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES05736317T Active ES2530694T3 (es) 2004-04-23 2005-04-05 Factor de permisividad celular para virus, y usos del mismo

Country Status (22)

Country Link
US (4) US7754464B2 (es)
EP (2) EP2520310B1 (es)
JP (2) JP5273642B2 (es)
CN (1) CN102220289B (es)
AR (3) AR049033A1 (es)
AU (2) AU2005240002B2 (es)
BR (1) BRPI0508928B1 (es)
CA (1) CA2564769C (es)
CL (1) CL2008002323A1 (es)
DK (1) DK1742658T3 (es)
EA (1) EA013071B1 (es)
ES (2) ES2530694T3 (es)
HK (1) HK1109065A1 (es)
IL (1) IL178160A0 (es)
MA (1) MA28544B1 (es)
MX (1) MXPA06012216A (es)
NO (1) NO341211B1 (es)
NZ (1) NZ550145A (es)
PL (1) PL1742658T3 (es)
TW (2) TWI354025B (es)
UY (1) UY28867A1 (es)
WO (1) WO2005107796A2 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2530694T3 (es) * 2004-04-23 2015-03-04 Zoetis P & U Llc Factor de permisividad celular para virus, y usos del mismo
CN101668846B (zh) 2007-01-12 2014-03-12 伊利诺伊大学评议会 用于猪繁殖与呼吸综合征（prrs）病毒生长的非猿猴细胞
CA2694476C (en) * 2007-07-27 2017-06-27 Universiteit Gent Permissive cells and uses thereof
UA108902C2 (uk) * 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
KR20150020209A (ko) * 2012-05-17 2015-02-25 조에티스 엘엘씨 이유 전 돼지 생식기 호흡기 증후군(prrs) 바이러스에 대한 효과적인 백신접종
CN103525766B (zh) * 2013-03-24 2015-06-17 西北农林科技大学 一种猪肾细胞系及其应用
GB201313235D0 (en) 2013-07-24 2013-09-04 Univ Edinburgh Antiviral Compositions Methods and Animals
CN104459160A (zh) * 2014-12-30 2015-03-25 洛阳普莱柯万泰生物技术有限公司 试剂盒及其制备方法和使用方法
GB201617559D0 (en) 2016-10-17 2016-11-30 University Court Of The University Of Edinburgh The Swine comprising modified cd163 and associated methods
CN110072547B (zh) * 2016-12-14 2024-04-30 硕腾服务有限责任公司 断奶前对抗欧洲猪繁殖与呼吸综合征(prrs)病毒株的有效疫苗接种
CN108103099B (zh) * 2017-12-18 2022-03-04 中山大学 一种抗蓝耳病Marc-145细胞系及其制备方法和应用
CN108893450B (zh) * 2018-08-13 2022-04-19 江苏省农业科学院 先天性免疫系统重构的bhk21细胞群及其细胞克隆增毒应用
CN111996213A (zh) * 2020-02-06 2020-11-27 广西大学 猪繁殖与呼吸综合征病毒双荧光标记基因重组毒株的构建方法
KR102254246B1 (ko) * 2020-03-23 2021-05-20 큐벳 주식회사 항-cd163 항체 또는 이의 항원 결합 단편을 인코딩하는 핵산 분자 및 이를 포함하는 아데노바이러스 벡터, 및 이의 아프리카 돼지열병의 예방 또는 치료용도
US11796548B2 (en) * 2020-04-22 2023-10-24 The United States Of America, As Represented By The Secretary Of Agriculture Continuous stable cell line for identification of infectious African swine fever virus in clinical samples

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Also Published As

Publication number Publication date
US9102912B2 (en) 2015-08-11
US20140141492A1 (en) 2014-05-22
JP5600340B2 (ja) 2014-10-01
AR049033A1 (es) 2006-06-21
TWI438278B (zh) 2014-05-21
MXPA06012216A (es) 2007-01-17
AR084530A2 (es) 2013-05-22
PL1742658T3 (pl) 2015-05-29
TWI354025B (en) 2011-12-11
JP2013078324A (ja) 2013-05-02
TW200604343A (en) 2006-02-01
US8486685B2 (en) 2013-07-16
NO20065115L (no) 2006-11-06
CA2564769C (en) 2013-12-17
UY28867A1 (es) 2005-11-30
JP5273642B2 (ja) 2013-08-28
AU2009202410A1 (en) 2009-07-09
US8058050B2 (en) 2011-11-15
WO2005107796A2 (en) 2005-11-17
CA2564769A1 (en) 2005-11-17
MA28544B1 (fr) 2007-04-03
EA200601677A1 (ru) 2007-10-26
US20100273238A1 (en) 2010-10-28
US20120015425A1 (en) 2012-01-19
ES2530694T3 (es) 2015-03-04
US20050271685A1 (en) 2005-12-08
JP2007533321A (ja) 2007-11-22
AR084529A2 (es) 2013-05-22
CN102220289A (zh) 2011-10-19
EP1742658A2 (en) 2007-01-17
NZ550145A (en) 2009-07-31
WO2005107796A3 (en) 2007-04-12
DK1742658T3 (en) 2015-01-19
BRPI0508928B1 (pt) 2015-10-06
NO341211B1 (no) 2017-09-11
EA013071B1 (ru) 2010-02-26
EP2520310A1 (en) 2012-11-07
EP1742658A4 (en) 2007-11-28
AU2005240002B2 (en) 2009-06-18
US7754464B2 (en) 2010-07-13
AU2005240002A1 (en) 2005-11-17
CL2008002323A1 (es) 2008-12-19
CN102220289B (zh) 2014-05-21
BRPI0508928A (pt) 2007-08-14
EP1742658B1 (en) 2014-12-24
HK1109065A1 (en) 2008-05-30
EP2520310B1 (en) 2016-03-30
TW201134944A (en) 2011-10-16
IL178160A0 (en) 2006-12-31

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