ES2622087T3 - Vacuna recombinante contra paramyxovirus aviar y procedimiento de fabricación y utilización de la misma - Google Patents

Vacuna recombinante contra paramyxovirus aviar y procedimiento de fabricación y utilización de la misma Download PDF

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Publication number
ES2622087T3
ES2622087T3 ES10747133T ES10747133T ES2622087T3 ES 2622087 T3 ES2622087 T3 ES 2622087T3 ES 10747133 T ES10747133 T ES 10747133T ES 10747133 T ES10747133 T ES 10747133T ES 2622087 T3 ES2622087 T3 ES 2622087T3
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polynucleotide
ampv
viral vector
open reading
pathogen
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Michel Bublot
Teshome Mebatsion
Joyce Pritchard
Egbert Mundt
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University of Georgia
University of Georgia Research Foundation Inc UGARF
Boehringer Ingelheim Animal Health USA Inc
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University of Georgia
University of Georgia Research Foundation Inc UGARF
Merial Inc
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61P31/18—Antivirals for RNA viruses for HIV
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
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    • C12N2760/18011—Paramyxoviridae
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Abstract

Vacuna que comprende (i) un vector viral AMPV recombinante y (ii) un portador farmacéutica o veterinariamente aceptable, en la que el vector viral AMPV es AMPV-8 y en la que el vector viral AMPV comprende un polinucleótido que tiene al menos un 90% de identidad de secuencia con un polinucleótido que tiene la secuencia como está expuesta en la SEQ ID NO: 1 o un polinucleótido complementario a un polinucleótido que tiene al menos un 90% de identidad de secuencia con un polinucleótido que tiene la secuencia como se expone en SEQ ID NO: 1; en la que el vector viral APMV comprende además un polinucleótido aislado que codifica un antígeno de un patógeno, en la que el patógeno es un patógeno aviar, felino, canino, equino, bovino, ovino, caprino o porcino, en la que el polinucleótido se inserta en una región no esencial del genoma de APMV, y además en la que la región no esencial se selecciona entre las regiones que consisten en la región no traducida situada en dirección 5' del marco de lectura abierto de NP, las regiones intergénicas entre dos marcos de lectura abiertos del genoma de APMV, y la región no traducida localizada en dirección 3' del marco de lectura abierto de L.
ES10747133T 2009-08-21 2010-08-20 Vacuna recombinante contra paramyxovirus aviar y procedimiento de fabricación y utilización de la misma Active ES2622087T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23591209P 2009-08-21 2009-08-21
PCT/US2010/046179 WO2011022656A2 (en) 2009-08-21 2010-08-20 Recombinant avian paramyxovirus vaccine and method for making and using thereof

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ES2622087T3 true ES2622087T3 (es) 2017-07-05

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ES16204538T Active ES2867457T3 (es) 2009-08-21 2010-08-20 Vacuna recombinante contra paramyxovirus aviar y procedimiento de fabricación y utilización de la misma
ES10747133T Active ES2622087T3 (es) 2009-08-21 2010-08-20 Vacuna recombinante contra paramyxovirus aviar y procedimiento de fabricación y utilización de la misma

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US (1) US8486418B2 (es)
EP (2) EP2467158B1 (es)
JP (2) JP6221167B2 (es)
KR (1) KR101745029B1 (es)
CN (2) CN105331633A (es)
BR (1) BR112012003837B8 (es)
CA (1) CA2771540C (es)
CL (2) CL2012000447A1 (es)
CO (1) CO6511253A2 (es)
ES (2) ES2867457T3 (es)
HU (2) HUE053237T2 (es)
MX (1) MX2012002114A (es)
PL (2) PL2467158T3 (es)
PT (2) PT3210622T (es)
RU (2) RU2592544C2 (es)
SG (2) SG10201405123WA (es)
UA (1) UA110328C2 (es)
WO (1) WO2011022656A2 (es)
ZA (1) ZA201201245B (es)

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CN102573901B (zh) 2015-11-25
UA110328C2 (en) 2015-12-25
BR112012003837A2 (pt) 2016-11-16
EP2467158B1 (en) 2017-01-25
BR112012003837B8 (pt) 2022-10-18
PT2467158T (pt) 2017-05-04
EP3210622A2 (en) 2017-08-30
CN105331633A (zh) 2016-02-17
US20110081374A1 (en) 2011-04-07
RU2016112465A3 (es) 2020-01-28
JP6221167B2 (ja) 2017-11-01
RU2592544C2 (ru) 2016-07-20
PL3210622T3 (pl) 2021-06-28
SG10201405123WA (en) 2014-12-30
HUE033886T2 (en) 2018-01-29
CN102573901A (zh) 2012-07-11
WO2011022656A3 (en) 2011-05-05
KR101745029B1 (ko) 2017-06-08
JP2013502225A (ja) 2013-01-24
CL2012000447A1 (es) 2012-08-31
CA2771540A1 (en) 2011-02-24
JP2016041079A (ja) 2016-03-31
PT3210622T (pt) 2021-03-03
CO6511253A2 (es) 2012-08-31
CL2015002175A1 (es) 2016-04-22
ES2867457T3 (es) 2021-10-20
SG178523A1 (en) 2012-03-29
ZA201201245B (en) 2012-10-31
EP3210622A3 (en) 2017-11-29
MX2012002114A (es) 2012-08-08
KR20120059570A (ko) 2012-06-08
PL2467158T3 (pl) 2017-07-31
RU2016112465A (ru) 2018-11-27
EP2467158A2 (en) 2012-06-27
US8486418B2 (en) 2013-07-16
RU2012110576A (ru) 2013-09-27
EP3210622B1 (en) 2020-12-16
CA2771540C (en) 2019-01-15
HUE053237T2 (hu) 2021-06-28
WO2011022656A2 (en) 2011-02-24

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