EA200601677A1 - Клеточный фактор пермиссивности в отношении вирусов и его применения - Google Patents

Клеточный фактор пермиссивности в отношении вирусов и его применения

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Publication number
EA200601677A1
EA200601677A1 EA200601677A EA200601677A EA200601677A1 EA 200601677 A1 EA200601677 A1 EA 200601677A1 EA 200601677 A EA200601677 A EA 200601677A EA 200601677 A EA200601677 A EA 200601677A EA 200601677 A1 EA200601677 A1 EA 200601677A1
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EA
Eurasian Patent Office
Prior art keywords
viruses
applications
performance factor
cellular performance
cellular
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EA200601677A
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English (en)
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EA013071B1 (ru
Inventor
Джей Грегори Калверт
Шелли Линн Шилдс
Дейвид Иуэлл Слейд
Сиао - Кун Ван Велч
Original Assignee
ФАРМАЦИЯ ЭНД АПДЖОН КОМПАНИ ЭлЭлСи
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Publication of EA200601677A1 publication Critical patent/EA200601677A1/ru
Publication of EA013071B1 publication Critical patent/EA013071B1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0684Cells of the urinary tract or kidneys
    • C12N5/0686Kidney cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0688Cells from the lungs or the respiratory tract
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2510/00Genetically modified cells
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    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
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    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10051Methods of production or purification of viral material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

В настоящем изобретении предложены способы и композиции, относящиеся к получению клеток-хозяев, пермиссивных в отношении роста вирусов, в частности вируса репродуктивно-респираторного синдрома свиней (PRRS).
EA200601677A 2004-04-23 2005-04-05 Способ получения вируса репродуктивно-респираторного синдрома свиней (pprsv) и способ получения pprsv вакцины EA013071B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56521404P 2004-04-23 2004-04-23
US63473604P 2004-12-09 2004-12-09
PCT/US2005/011502 WO2005107796A2 (en) 2004-04-23 2005-04-05 Cellular permissivity factor for viruses, and uses thereof

Publications (2)

Publication Number Publication Date
EA200601677A1 true EA200601677A1 (ru) 2007-10-26
EA013071B1 EA013071B1 (ru) 2010-02-26

Family

ID=35320736

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601677A EA013071B1 (ru) 2004-04-23 2005-04-05 Способ получения вируса репродуктивно-респираторного синдрома свиней (pprsv) и способ получения pprsv вакцины

Country Status (22)

Country Link
US (4) US7754464B2 (ru)
EP (2) EP2520310B1 (ru)
JP (2) JP5273642B2 (ru)
CN (1) CN102220289B (ru)
AR (3) AR049033A1 (ru)
AU (2) AU2005240002B2 (ru)
BR (1) BRPI0508928B1 (ru)
CA (1) CA2564769C (ru)
CL (1) CL2008002323A1 (ru)
DK (1) DK1742658T3 (ru)
EA (1) EA013071B1 (ru)
ES (2) ES2530694T3 (ru)
HK (1) HK1109065A1 (ru)
IL (1) IL178160A0 (ru)
MA (1) MA28544B1 (ru)
MX (1) MXPA06012216A (ru)
NO (1) NO341211B1 (ru)
NZ (1) NZ550145A (ru)
PL (1) PL1742658T3 (ru)
TW (2) TWI354025B (ru)
UY (1) UY28867A1 (ru)
WO (1) WO2005107796A2 (ru)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2530694T3 (es) * 2004-04-23 2015-03-04 Zoetis P & U Llc Factor de permisividad celular para virus, y usos del mismo
CN101668846B (zh) 2007-01-12 2014-03-12 伊利诺伊大学评议会 用于猪繁殖与呼吸综合征(prrs)病毒生长的非猿猴细胞
CA2694476C (en) * 2007-07-27 2017-06-27 Universiteit Gent Permissive cells and uses thereof
UA108902C2 (uk) * 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
KR20150020209A (ko) * 2012-05-17 2015-02-25 조에티스 엘엘씨 이유 전 돼지 생식기 호흡기 증후군(prrs) 바이러스에 대한 효과적인 백신접종
CN103525766B (zh) * 2013-03-24 2015-06-17 西北农林科技大学 一种猪肾细胞系及其应用
GB201313235D0 (en) 2013-07-24 2013-09-04 Univ Edinburgh Antiviral Compositions Methods and Animals
CN104459160A (zh) * 2014-12-30 2015-03-25 洛阳普莱柯万泰生物技术有限公司 试剂盒及其制备方法和使用方法
GB201617559D0 (en) 2016-10-17 2016-11-30 University Court Of The University Of Edinburgh The Swine comprising modified cd163 and associated methods
CN110072547B (zh) * 2016-12-14 2024-04-30 硕腾服务有限责任公司 断奶前对抗欧洲猪繁殖与呼吸综合征(prrs)病毒株的有效疫苗接种
CN108103099B (zh) * 2017-12-18 2022-03-04 中山大学 一种抗蓝耳病Marc-145细胞系及其制备方法和应用
CN108893450B (zh) * 2018-08-13 2022-04-19 江苏省农业科学院 先天性免疫系统重构的bhk21细胞群及其细胞克隆增毒应用
CN111996213A (zh) * 2020-02-06 2020-11-27 广西大学 猪繁殖与呼吸综合征病毒双荧光标记基因重组毒株的构建方法
KR102254246B1 (ko) * 2020-03-23 2021-05-20 큐벳 주식회사 항-cd163 항체 또는 이의 항원 결합 단편을 인코딩하는 핵산 분자 및 이를 포함하는 아데노바이러스 벡터, 및 이의 아프리카 돼지열병의 예방 또는 치료용도
US11796548B2 (en) * 2020-04-22 2023-10-24 The United States Of America, As Represented By The Secretary Of Agriculture Continuous stable cell line for identification of infectious African swine fever virus in clinical samples

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4517288A (en) 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
CA1291031C (en) 1985-12-23 1991-10-22 Nikolaas C.J. De Jaeger Method for the detection of specific binding agents and their correspondingbindable substances
CA1303983C (en) 1987-03-27 1992-06-23 Robert W. Rosenstein Solid phase assay
WO1990005183A1 (en) 1988-10-31 1990-05-17 Immunex Corporation Interleukin-4 receptors
GB2236186B (en) 1989-08-22 1994-01-05 Finnigan Mat Gmbh Process and device for laser desorption of analyte molecular ions, especially of biomolecules
AU645294B2 (en) 1989-12-22 1994-01-13 Merck Serono Sa Endogenous gene expression modification with regulatory element
AU651596B2 (en) 1990-06-05 1994-07-28 Immunex Corporation Type II interleukin-1 receptors
AU664847B2 (en) 1991-05-15 1995-12-07 Cell Genesys, Inc. Genomic modifications with homologous DNA targeting
US5846805A (en) 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
US5514545A (en) 1992-06-11 1996-05-07 Trustees Of The University Of Pennsylvania Method for characterizing single cells based on RNA amplification for diagnostics and therapeutics
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
ES2201077T3 (es) 1993-05-28 2004-03-16 Baylor College Of Medicine Metodo y espectrometro de masas para la desorcion e ionizacion de analitos.
DK0676467T3 (da) * 1994-04-11 2002-01-21 Akzo Nobel Nv Europæiske vaccinestammer af det porcine reproduktive respiratoriske syndromvirus (PRRSV)
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
WO1998035023A1 (en) * 1997-02-07 1998-08-13 Origen, Inc. Method for growing porcine reproductive and respiratory syndrome virus for use as vaccines and diagnostic assays
US6740490B2 (en) 2001-01-29 2004-05-25 Kansas State University Research Foundation Identification and applications of porcine reproductive and respiratory syndrome virus host susceptibility factor(s) for improved swine breeding
WO2003010200A2 (en) 2001-07-24 2003-02-06 Akzo Nobel, N.V. Nucleic acid encoding polypeptide involved in cellular entrance of the prrs virus
WO2003100419A1 (en) * 2002-05-27 2003-12-04 Bioceros B.V. Methods for using the cd163 pathway for modulating an immune response
ES2530694T3 (es) * 2004-04-23 2015-03-04 Zoetis P & U Llc Factor de permisividad celular para virus, y usos del mismo

Also Published As

Publication number Publication date
US9102912B2 (en) 2015-08-11
US20140141492A1 (en) 2014-05-22
ES2570665T3 (es) 2016-05-19
JP5600340B2 (ja) 2014-10-01
AR049033A1 (es) 2006-06-21
TWI438278B (zh) 2014-05-21
MXPA06012216A (es) 2007-01-17
AR084530A2 (es) 2013-05-22
PL1742658T3 (pl) 2015-05-29
TWI354025B (en) 2011-12-11
JP2013078324A (ja) 2013-05-02
TW200604343A (en) 2006-02-01
US8486685B2 (en) 2013-07-16
NO20065115L (no) 2006-11-06
CA2564769C (en) 2013-12-17
UY28867A1 (es) 2005-11-30
JP5273642B2 (ja) 2013-08-28
AU2009202410A1 (en) 2009-07-09
US8058050B2 (en) 2011-11-15
WO2005107796A2 (en) 2005-11-17
CA2564769A1 (en) 2005-11-17
MA28544B1 (fr) 2007-04-03
US20100273238A1 (en) 2010-10-28
US20120015425A1 (en) 2012-01-19
ES2530694T3 (es) 2015-03-04
US20050271685A1 (en) 2005-12-08
JP2007533321A (ja) 2007-11-22
AR084529A2 (es) 2013-05-22
CN102220289A (zh) 2011-10-19
EP1742658A2 (en) 2007-01-17
NZ550145A (en) 2009-07-31
WO2005107796A3 (en) 2007-04-12
DK1742658T3 (en) 2015-01-19
BRPI0508928B1 (pt) 2015-10-06
NO341211B1 (no) 2017-09-11
EA013071B1 (ru) 2010-02-26
EP2520310A1 (en) 2012-11-07
EP1742658A4 (en) 2007-11-28
AU2005240002B2 (en) 2009-06-18
US7754464B2 (en) 2010-07-13
AU2005240002A1 (en) 2005-11-17
CL2008002323A1 (es) 2008-12-19
CN102220289B (zh) 2014-05-21
BRPI0508928A (pt) 2007-08-14
EP1742658B1 (en) 2014-12-24
HK1109065A1 (en) 2008-05-30
EP2520310B1 (en) 2016-03-30
TW201134944A (en) 2011-10-16
IL178160A0 (en) 2006-12-31

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