BRPI0516221A - método de produção de vìrus de uma cultura de células, composição, e, método de produção de reovìrus infeccioso - Google Patents
método de produção de vìrus de uma cultura de células, composição, e, método de produção de reovìrus infecciosoInfo
- Publication number
- BRPI0516221A BRPI0516221A BRPI0516221-1A BRPI0516221A BRPI0516221A BR PI0516221 A BRPI0516221 A BR PI0516221A BR PI0516221 A BRPI0516221 A BR PI0516221A BR PI0516221 A BRPI0516221 A BR PI0516221A
- Authority
- BR
- Brazil
- Prior art keywords
- virus
- production
- cell culture
- composition
- infectious
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12051—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
MéTODO DE PRODUçãO DE VìRUS DE UMA CULTURA DE CéLULAS, COMPOSIçãO, E, MéTODO DE PRODUçãO DE REOVìRUS INFECCIOSO. A invenção refere-se a um método melhorado de purificação de vírus, particularmente reovírus. O vírus infeccioso pode ser extraído de uma cultura celular com um detergente para produzir altos títulos de vírus, e o vírus pode então ser purificado por etapas simples, tais como filtração e cromatografia em coluna. Os vírus e as composições que compreendem os vírus preparados de acordo com a presente invenção são também providos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62125704P | 2004-10-22 | 2004-10-22 | |
PCT/CA2005/001617 WO2006042414A1 (en) | 2004-10-22 | 2005-10-21 | Improved viral purification methods |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0516221A true BRPI0516221A (pt) | 2008-08-26 |
Family
ID=36202651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0516221-1A BRPI0516221A (pt) | 2004-10-22 | 2005-10-21 | método de produção de vìrus de uma cultura de células, composição, e, método de produção de reovìrus infeccioso |
Country Status (15)
Country | Link |
---|---|
US (1) | US7901921B2 (pt) |
EP (1) | EP1814982B1 (pt) |
JP (2) | JP4898690B2 (pt) |
CN (2) | CN105062980A (pt) |
AU (1) | AU2005297372B2 (pt) |
BR (1) | BRPI0516221A (pt) |
CA (1) | CA2584142C (pt) |
DK (1) | DK1814982T3 (pt) |
ES (1) | ES2562237T3 (pt) |
HK (1) | HK1100959A1 (pt) |
IL (1) | IL182562A0 (pt) |
MX (1) | MX2007004696A (pt) |
SG (1) | SG156673A1 (pt) |
WO (1) | WO2006042414A1 (pt) |
ZA (1) | ZA200704034B (pt) |
Families Citing this family (60)
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WO2003093463A1 (en) * | 2002-04-30 | 2003-11-13 | Oncolytics Biotech Inc. | Improved viral purification methods |
US10668119B2 (en) | 2005-08-01 | 2020-06-02 | Virocure, Inc. | Attenuated reovirus |
EP1917351A4 (en) * | 2005-08-01 | 2009-12-16 | Univ Technologies Int | ATTENUATED REOVIRUS |
US20080131955A1 (en) * | 2006-11-30 | 2008-06-05 | Canon U.S. Life Sciences, Inc. | Method of Separating Target DNA from Mixed DNA |
US10369171B2 (en) | 2007-03-13 | 2019-08-06 | Virocure, Inc. | Attenuated reoviruses for selection of cell populations |
EP2240573A4 (en) * | 2008-02-12 | 2011-08-31 | Sanofi Pasteur Ltd | METHOD USING ION EXCHANGE AND GELFILTRATION CHROMATOGRAPHY FOR POXVIRUS CLEANING |
CN101270350A (zh) * | 2008-03-05 | 2008-09-24 | 辽宁依生生物制药有限公司 | 一种提取狂犬病病毒的方法 |
US8445270B2 (en) | 2009-05-12 | 2013-05-21 | Transgene S.A. | Immortalized avian cell lines and use thereof |
CN102191226A (zh) * | 2010-03-08 | 2011-09-21 | 北京清大天一科技有限公司 | 细胞培养混合物的分离纯化方法 |
US9644187B2 (en) | 2010-04-14 | 2017-05-09 | Emd Millipore Corporation | Methods of producing high titer, high purity virus stocks and methods of use thereof |
TW201233802A (en) | 2010-12-02 | 2012-08-16 | Oncolytics Biotech Inc | Liquid viral formulations |
DK2646052T3 (en) | 2010-12-02 | 2017-07-17 | Oncolytics Biotech Inc | LYOPHILIZED VIRAL FORMULATIONS |
DK2702147T3 (da) | 2011-04-29 | 2020-09-28 | Oncolytics Biotech Inc | Fremgangsmåder til oprensning af vira ved hjælp af gelpermeationskromatografi |
CN102628030B (zh) * | 2012-01-20 | 2013-12-04 | 宁波大学 | 三疣梭子蟹呼肠孤病毒的鸡胚培养方法 |
CN103571800B (zh) * | 2012-07-27 | 2018-04-24 | 江苏康润生物科技有限公司 | 一种去除疫苗中宿主dna的方法 |
US10577627B2 (en) | 2014-06-09 | 2020-03-03 | Voyager Therapeutics, Inc. | Chimeric capsids |
EP3172317B1 (en) * | 2014-07-24 | 2019-05-01 | Janssen Vaccines & Prevention B.V. | Process for the purification of poliovirus from cell cultures |
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EP3218484A4 (en) | 2014-11-14 | 2018-05-30 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
RU2749882C2 (ru) | 2014-11-14 | 2021-06-18 | Вояджер Терапьютикс, Инк. | Модулирующие полинуклеотиды |
US11697825B2 (en) | 2014-12-12 | 2023-07-11 | Voyager Therapeutics, Inc. | Compositions and methods for the production of scAAV |
EP3054007A1 (en) | 2015-02-09 | 2016-08-10 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Recombinant adeno-associated virus particle purification comprising an immuno-affinity purification step |
WO2016201224A1 (en) * | 2015-06-10 | 2016-12-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Processes for production and purification of nucleic acid-containing compositions |
US20180230489A1 (en) | 2015-10-28 | 2018-08-16 | Voyager Therapeutics, Inc. | Regulatable expression using adeno-associated virus (aav) |
EP3448874A4 (en) | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
US11299751B2 (en) | 2016-04-29 | 2022-04-12 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
JP7220080B2 (ja) | 2016-05-18 | 2023-02-09 | ボイジャー セラピューティクス インコーポレイテッド | ハンチントン病治療組成物及び方法 |
RU2758488C2 (ru) | 2016-05-18 | 2021-10-28 | Вояджер Терапьютикс, Инк. | Модулирующие полинуклеотиды |
EP3506817A4 (en) | 2016-08-30 | 2020-07-22 | The Regents of The University of California | METHOD FOR BIOMEDICAL TARGETING AND RELEASE, AND DEVICES AND SYSTEMS FOR IMPLEMENTING THEM |
WO2018204786A1 (en) | 2017-05-05 | 2018-11-08 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
WO2018204803A1 (en) | 2017-05-05 | 2018-11-08 | Voyager Therapeutics, Inc. | Compositions and methods of treating huntington's disease |
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US10851350B1 (en) * | 2017-06-27 | 2020-12-01 | Genelux Corporation | Bioreactor production of virus from adherent cells |
JP7229989B2 (ja) | 2017-07-17 | 2023-02-28 | ボイジャー セラピューティクス インコーポレイテッド | 軌道アレイガイドシステム |
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EP3697908A1 (en) | 2017-10-16 | 2020-08-26 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (als) |
EP4124658A3 (en) | 2017-10-16 | 2023-04-19 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (als) |
US11603527B2 (en) * | 2017-12-27 | 2023-03-14 | Global Life Sciences Solutions Usa Llc | Method and kit for viral vector isolation |
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US11690907B2 (en) | 2018-06-12 | 2023-07-04 | Kbio Holdings Limited | Vaccines formed by virus and antigen conjugation |
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US11999975B2 (en) * | 2018-07-04 | 2024-06-04 | Probiogen Ag | Method for purifying an enveloped virus |
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US20220064671A1 (en) | 2019-01-18 | 2022-03-03 | Voyager Therapeutics, Inc. | Methods and systems for producing aav particles |
KR102228267B1 (ko) * | 2019-01-25 | 2021-03-17 | 바이로큐어 주식회사 | Bhk-21 세포를 이용한 바이러스 생산방법 |
EP3962536A1 (en) | 2019-04-29 | 2022-03-09 | Voyager Therapeutics, Inc. | Systems and methods for producing baculoviral infected insect cells (biics) in bioreactors |
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US20220364114A1 (en) | 2019-08-26 | 2022-11-17 | Voyager Therapeutics, Inc. | Controlled expression of viral proteins |
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-
2005
- 2005-10-20 US US11/255,800 patent/US7901921B2/en active Active
- 2005-10-21 BR BRPI0516221-1A patent/BRPI0516221A/pt not_active IP Right Cessation
- 2005-10-21 EP EP05799134.1A patent/EP1814982B1/en active Active
- 2005-10-21 CN CN201510475203.0A patent/CN105062980A/zh active Pending
- 2005-10-21 MX MX2007004696A patent/MX2007004696A/es active IP Right Grant
- 2005-10-21 JP JP2007537090A patent/JP4898690B2/ja active Active
- 2005-10-21 CN CNA2005800444124A patent/CN101098959A/zh active Pending
- 2005-10-21 ES ES05799134.1T patent/ES2562237T3/es active Active
- 2005-10-21 ZA ZA200704034A patent/ZA200704034B/xx unknown
- 2005-10-21 SG SG200907055-8A patent/SG156673A1/en unknown
- 2005-10-21 DK DK05799134.1T patent/DK1814982T3/en active
- 2005-10-21 CA CA2584142A patent/CA2584142C/en active Active
- 2005-10-21 WO PCT/CA2005/001617 patent/WO2006042414A1/en active Application Filing
- 2005-10-21 AU AU2005297372A patent/AU2005297372B2/en active Active
-
2007
- 2007-04-16 IL IL182562A patent/IL182562A0/en unknown
- 2007-08-20 HK HK07109008.4A patent/HK1100959A1/xx unknown
-
2011
- 2011-11-28 JP JP2011258983A patent/JP2012040026A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1814982A4 (en) | 2009-03-04 |
WO2006042414A1 (en) | 2006-04-27 |
ES2562237T3 (es) | 2016-03-03 |
US7901921B2 (en) | 2011-03-08 |
IL182562A0 (en) | 2007-07-24 |
JP2008516616A (ja) | 2008-05-22 |
MX2007004696A (es) | 2007-06-14 |
CN105062980A (zh) | 2015-11-18 |
JP4898690B2 (ja) | 2012-03-21 |
SG156673A1 (en) | 2009-11-26 |
EP1814982A1 (en) | 2007-08-08 |
CA2584142A1 (en) | 2006-04-27 |
US20060088869A1 (en) | 2006-04-27 |
DK1814982T3 (en) | 2016-03-21 |
ZA200704034B (en) | 2008-08-27 |
HK1100959A1 (en) | 2007-10-05 |
CA2584142C (en) | 2011-11-29 |
EP1814982B1 (en) | 2015-12-23 |
AU2005297372B2 (en) | 2010-08-26 |
JP2012040026A (ja) | 2012-03-01 |
AU2005297372A1 (en) | 2006-04-27 |
CN101098959A (zh) | 2008-01-02 |
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