FR2640638B1
(fr)
|
1988-12-20 |
1991-02-15 |
Commissariat Energie Atomique |
Bioreacteur et dispositif pour la culture de cellules animales
|
WO1991018088A1
(en)
|
1990-05-23 |
1991-11-28 |
The United States Of America, Represented By The Secretary, United States Department Of Commerce |
Adeno-associated virus (aav)-based eucaryotic vectors
|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
GB9027917D0
(en)
*
|
1990-12-21 |
1991-02-13 |
Ici Plc |
Expression systems
|
US5252479A
(en)
|
1991-11-08 |
1993-10-12 |
Research Corporation Technologies, Inc. |
Safe vector for gene therapy
|
US5587308A
(en)
|
1992-06-02 |
1996-12-24 |
The United States Of America As Represented By The Department Of Health & Human Services |
Modified adeno-associated virus vector capable of expression from a novel promoter
|
US6268213B1
(en)
|
1992-06-03 |
2001-07-31 |
Richard Jude Samulski |
Adeno-associated virus vector and cis-acting regulatory and promoter elements capable of expressing at least one gene and method of using same for gene therapy
|
US5693531A
(en)
|
1993-11-24 |
1997-12-02 |
The United States Of America As Represented By The Department Of Health And Human Services |
Vector systems for the generation of adeno-associated virus particles
|
ATE386131T1
(de)
|
1994-04-13 |
2008-03-15 |
Univ Rockefeller |
Aav-vermittelte überbringung von dna in zellen des nervensystems
|
US5658785A
(en)
|
1994-06-06 |
1997-08-19 |
Children's Hospital, Inc. |
Adeno-associated virus materials and methods
|
US20020159979A1
(en)
|
1994-06-06 |
2002-10-31 |
Children's Hospital, Inc. |
Adeno-associated virus materials and methods
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
US5856152A
(en)
|
1994-10-28 |
1999-01-05 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV vector and methods of use therefor
|
US5625048A
(en)
|
1994-11-10 |
1997-04-29 |
The Regents Of The University Of California |
Modified green fluorescent proteins
|
US5652224A
(en)
|
1995-02-24 |
1997-07-29 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for gene therapy for the treatment of defects in lipoprotein metabolism
|
US5741657A
(en)
|
1995-03-20 |
1998-04-21 |
The Regents Of The University Of California |
Fluorogenic substrates for β-lactamase and methods of use
|
US5756283A
(en)
|
1995-06-05 |
1998-05-26 |
The Trustees Of The University Of Pennsylvania |
Method for improved production of recombinant adeno-associated viruses for gene therapy
|
US6281010B1
(en)
|
1995-06-05 |
2001-08-28 |
The Trustees Of The University Of Pennsylvania |
Adenovirus gene therapy vehicle and cell line
|
US5688676A
(en)
|
1995-06-07 |
1997-11-18 |
Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
US5741683A
(en)
|
1995-06-07 |
1998-04-21 |
The Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
US6197293B1
(en)
|
1997-03-03 |
2001-03-06 |
Calydon, Inc. |
Adenovirus vectors specific for cells expressing androgen receptor and methods of use thereof
|
US6676935B2
(en)
|
1995-06-27 |
2004-01-13 |
Cell Genesys, Inc. |
Tissue specific adenoviral vectors
|
US6143548A
(en)
|
1995-08-30 |
2000-11-07 |
Genzyme Corporation |
Chromatographic purification of adeno-associated virus (AAV)
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
US5846528A
(en)
|
1996-01-18 |
1998-12-08 |
Avigen, Inc. |
Treating anemia using recombinant adeno-associated virus virions comprising an EPO DNA sequence
|
US5858351A
(en)
|
1996-01-18 |
1999-01-12 |
Avigen, Inc. |
Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors
|
US5962313A
(en)
|
1996-01-18 |
1999-10-05 |
Avigen, Inc. |
Adeno-associated virus vectors comprising a gene encoding a lyosomal enzyme
|
US5952221A
(en)
|
1996-03-06 |
1999-09-14 |
Avigen, Inc. |
Adeno-associated virus vectors comprising a first and second nucleic acid sequence
|
US7026468B2
(en)
|
1996-07-19 |
2006-04-11 |
Valentis, Inc. |
Process and equipment for plasmid purification
|
IL128736A0
(en)
|
1996-09-06 |
2000-01-31 |
Univ Pennsylvania |
Methods using cre-lox for production of recombinant adeno-associated viruses
|
WO1998010088A1
(en)
|
1996-09-06 |
1998-03-12 |
Trustees Of The University Of Pennsylvania |
An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
|
WO1998009657A2
(en)
|
1996-09-06 |
1998-03-12 |
Trustees Of The University Of Pennsylvania |
Method for recombinant adeno-associated virus-directed gene therapy
|
US5866552A
(en)
|
1996-09-06 |
1999-02-02 |
The Trustees Of The University Of Pennsylvania |
Method for expressing a gene in the absence of an immune response
|
AU4255397A
(en)
|
1996-09-06 |
1998-03-26 |
Trustees Of The University Of Pennsylvania, The |
Chimpanzee adenovirus vectors
|
US20020037867A1
(en)
|
1999-02-26 |
2002-03-28 |
James M. Wilson |
Method for recombinant adeno-associated virus-directed gene therapy
|
WO1998011244A2
(en)
|
1996-09-11 |
1998-03-19 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Aav4 vector and uses thereof
|
US7732129B1
(en)
|
1998-12-01 |
2010-06-08 |
Crucell Holland B.V. |
Method for the production and purification of adenoviral vectors
|
CA2272820C
(en)
|
1996-11-20 |
2012-09-11 |
Introgen Therapeutics, Inc. |
An improved method for the production and purification of adenoviral vectors
|
US6541258B2
(en)
|
1996-12-18 |
2003-04-01 |
Targeted Genetics Corporation |
AAV split-packaging genes and cell lines comprising such genes for use in the production of recombinant AAV vectors
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
US6710036B2
(en)
|
1997-07-25 |
2004-03-23 |
Avigen, Inc. |
Induction of immune response to antigens expressed by recombinant adeno-associated virus
|
US6251677B1
(en)
|
1997-08-25 |
2001-06-26 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
US6989264B2
(en)
|
1997-09-05 |
2006-01-24 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
US6566118B1
(en)
|
1997-09-05 |
2003-05-20 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
AU9319198A
(en)
|
1997-09-19 |
1999-04-05 |
Trustees Of The University Of Pennsylvania, The |
Methods and vector constructs useful for production of recombinant aav
|
AU9774998A
(en)
|
1997-09-19 |
1999-04-12 |
Trustees Of The University Of Pennsylvania, The |
Method for gene transfer using bcl2 and compositions useful therein
|
CA2304168A1
(en)
|
1997-09-19 |
1999-04-01 |
The Trustees Of The University Of Pennsylvania |
Methods and cell line useful for production of recombinant adeno-associated viruses
|
US6642051B1
(en)
|
1997-10-21 |
2003-11-04 |
Targeted Genetics Corporation |
Amplifiable adeno-associated virus(AAV) packaging cassettes for the production of recombinant AAV vectors
|
IT1297074B1
(it)
|
1997-11-21 |
1999-08-03 |
Angeletti P Ist Richerche Bio |
Forme ormone-dipendenti delle proteine rep del virus adeno-associato (aav-2), sequenze di dna codificanti per esse, vettori che le
|
NZ505325A
(en)
|
1997-12-23 |
2003-07-25 |
Crucell Holland B |
Adeno-associated virus and adenovirus chimeric recombinant viruses useful for the integration of foreign genetic information into the chromosomal dna of target cells
|
US6410300B1
(en)
|
1998-01-12 |
2002-06-25 |
The University Of North Carolina At Chapel Hill |
Methods and formulations for mediating adeno-associated virus (AAV) attachment and infection and methods for purifying AAV
|
WO1999043360A1
(en)
|
1998-02-26 |
1999-09-02 |
The Trustees Of The University Of Pennsylvania |
Stable protection from dystrophic sarcolemmal degeneration and restoration of the sarcoglycan complex
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
US6521426B1
(en)
|
1998-04-08 |
2003-02-18 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Preparation of recombinant adenovirus carrying a rep gene of adeno-associated virus
|
FR2778413B1
(fr)
|
1998-05-07 |
2000-08-04 |
Immunotech Sa |
Nouveaux reactifs et methode de lyse des erythrocytes
|
EP1078096A1
(en)
|
1998-05-11 |
2001-02-28 |
Ariad Gene Therapeutics, Inc. |
Multiviral compositions and uses thereof
|
US6436392B1
(en)
|
1998-05-20 |
2002-08-20 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors
|
EP1849872A1
(en)
|
1998-05-20 |
2007-10-31 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors and uses thereof
|
EP1080218A1
(en)
|
1998-05-27 |
2001-03-07 |
University of Florida |
Method of preparing recombinant adeno-associated virus compositions by using an iodixanol gradient
|
EP1621625B1
(en)
|
1998-05-27 |
2009-05-13 |
Genzyme Corporation |
AAV vectors for the manufacture of medicaments for convection enhanced delivery
|
WO1999061595A2
(en)
|
1998-05-27 |
1999-12-02 |
Cell Genesys, Inc. |
Adeno-associated viral vector-mediated expression of factor viii activity
|
ES2326893T3
(es)
|
1998-05-27 |
2009-10-21 |
Genzyme Corporation |
Vectores aav para la fabricacion de medicamentos para administracion potenciada por conveccion.
|
JP4060531B2
(ja)
|
1998-05-28 |
2008-03-12 |
アメリカ合衆国 |
Aav5ベクターおよびその使用
|
US6984517B1
(en)
|
1998-05-28 |
2006-01-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector and uses thereof
|
GB2338236B
(en)
|
1998-06-13 |
2003-04-09 |
Aea Technology Plc |
Microbiological cell processing
|
US6900049B2
(en)
|
1998-09-10 |
2005-05-31 |
Cell Genesys, Inc. |
Adenovirus vectors containing cell status-specific response elements and methods of use thereof
|
US6416992B1
(en)
|
1998-10-13 |
2002-07-09 |
Avigen, Inc. |
Compositions and methods for producing recombinant adeno-associated virus
|
US6200560B1
(en)
|
1998-10-20 |
2001-03-13 |
Avigen, Inc. |
Adeno-associated virus vectors for expression of factor VIII by target cells
|
US6221349B1
(en)
|
1998-10-20 |
2001-04-24 |
Avigen, Inc. |
Adeno-associated vectors for expression of factor VIII by target cells
|
EP1124976A1
(en)
|
1998-10-27 |
2001-08-22 |
Crucell Holland B.V. |
Improved aav vector production
|
US6759237B1
(en)
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
US6689600B1
(en)
|
1998-11-16 |
2004-02-10 |
Introgen Therapeutics, Inc. |
Formulation of adenovirus for gene therapy
|
US6759050B1
(en)
|
1998-12-03 |
2004-07-06 |
Avigen, Inc. |
Excipients for use in adeno-associated virus pharmaceutical formulations, and pharmaceutical formulations made therewith
|
US6225113B1
(en)
|
1998-12-04 |
2001-05-01 |
Genvec, Inc. |
Use of trans-activation and cis-activation to modulate the persistence of expression of a transgene in an at least E4-deficient adenovirus
|
US6387368B1
(en)
|
1999-02-08 |
2002-05-14 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
DE19905501B4
(de)
|
1999-02-10 |
2005-05-19 |
MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie |
Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
|
US6509150B1
(en)
|
1999-03-05 |
2003-01-21 |
Universite De Nantes |
Compositions and methods for recombinant Adeno-Associated Virus production
|
US6258595B1
(en)
|
1999-03-18 |
2001-07-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
JP4693244B2
(ja)
|
1999-03-18 |
2011-06-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
|
CA2368194A1
(en)
|
1999-04-30 |
2000-11-09 |
University Of Florida |
Adeno-associated virus-delivered ribozyme compositions and methods of use
|
JP2003501067A
(ja)
|
1999-06-02 |
2003-01-14 |
トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
ヘルパーウイルスを要求する組み換えウイルス産生のために有用な組成物及び方法
|
CA2382483A1
(en)
|
1999-08-20 |
2001-03-01 |
Johns Hopkins University School Of Medicine |
Methods and compositions for the construction and use of fusion libraries
|
US6365394B1
(en)
|
1999-09-29 |
2002-04-02 |
The Trustees Of The University Of Pennsylvania |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
|
JP2003523320A
(ja)
|
1999-09-29 |
2003-08-05 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
ウイルスベクターの迅速なpeg改変方法、高められた遺伝子形質導入のための組成物、高められた物理的安定性を伴う組成物、およびそのための用途
|
EP1224313A1
(en)
|
1999-10-07 |
2002-07-24 |
University of Iowa Research Foundation |
Adeno-associated viruses and uses thereof
|
US7241447B1
(en)
|
1999-10-07 |
2007-07-10 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors and uses thereof
|
AU1436401A
(en)
|
1999-10-21 |
2001-05-14 |
Board Of Trustees Of The University Of Arkansas, The |
RepO-associated virus AAV REP78 major regulatory protein, mutants thereof and uses thereof
|
AU3642601A
(en)
|
1999-11-05 |
2001-05-30 |
Avigen, Inc. |
Ecdysone-inducible adeno-associated virus expression vectors
|
WO2001036603A2
(en)
|
1999-11-17 |
2001-05-25 |
Avigen, Inc. |
Recombinant adeno-associated virus virions for the treatment of lysosomal disorders
|
IL149667A0
(en)
|
1999-12-10 |
2002-11-10 |
Ariad Gene Therapeutics Inc Un |
Methods for expression of genes in primates
|
EP1228234A2
(en)
|
2000-03-14 |
2002-08-07 |
Neurologix, Inc. |
Production of chimeric capsid vectors
|
US7638120B2
(en)
|
2000-03-14 |
2009-12-29 |
Thomas Jefferson University |
High transgene expression of a pseudotyped adeno-associated virus type
|
US6468524B1
(en)
|
2000-03-22 |
2002-10-22 |
The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
AAV4 vector and uses thereof
|
US6855314B1
(en)
|
2000-03-22 |
2005-02-15 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector for transducing brain cells and lung cells
|
US7048920B2
(en)
|
2000-03-24 |
2006-05-23 |
Cell Genesys, Inc. |
Recombinant oncolytic adenovirus for human melanoma
|
GB0009887D0
(en)
|
2000-04-20 |
2000-06-07 |
Btg Int Ltd |
Cytotoxic agents
|
CA2406743A1
(en)
|
2000-04-28 |
2001-11-08 |
The Trustees Of The University Of Pennsylvania |
Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids
|
US20030013189A1
(en)
|
2000-04-28 |
2003-01-16 |
Wilson James M. |
Compositions and methods useful for non-invasive delivery of therapeutic molecules to the bloodstream
|
US7125705B2
(en)
|
2000-04-28 |
2006-10-24 |
Genzyme Corporation |
Polynucleotides for use in recombinant adeno-associated virus virion production
|
EP1299126B1
(en)
|
2000-05-23 |
2004-10-27 |
Neurologix, Inc. |
Glutamic acid decarboxylase (gad) delivery system for treating neurodegenerative diseases
|
US20020106381A1
(en)
|
2000-06-13 |
2002-08-08 |
High Katherine A. |
Methods for administering recombinant adeno-associated virus virions to humans previously exposed to adeno-associated virus
|
WO2002006483A1
(fr)
|
2000-07-18 |
2002-01-24 |
Takeda Chemical Industries, Ltd. |
Nouveau peptide actif sur le plan physiologique et utilisation associee
|
US6329181B1
(en)
|
2000-08-07 |
2001-12-11 |
Neurologix, Inc. |
Helper functions for recombinant vector production
|
US6593123B1
(en)
|
2000-08-07 |
2003-07-15 |
Avigen, Inc. |
Large-scale recombinant adeno-associated virus (rAAV) production and purification
|
AU2001294096A1
(en)
|
2000-08-17 |
2002-02-25 |
Uichi Ikeda |
Adeno-associated virus-mediated delivery of angiogenic factors
|
DE10044384A1
(de)
|
2000-09-08 |
2002-04-18 |
Medigene Ag |
Wirtszellen zur Verpackung von rekombinantem Adeno-assoziiertem Virus (rAAV), Verfahren zu ihrer Herstellung und deren Verwendung
|
FR2813891B1
(fr)
|
2000-09-14 |
2005-01-14 |
Immunotech Sa |
Reactif multifonctionnel pour erythrocytes mettant en jeu des carbamates et applications
|
GB0024550D0
(es)
*
|
2000-10-06 |
2000-11-22 |
Oxford Biomedica Ltd |
|
JP2002153278A
(ja)
|
2000-11-22 |
2002-05-28 |
Hisamitsu Pharmaceut Co Inc |
ウイルスベクターの製造に用いられる細胞、その製法およびその細胞を用いたウイルスベクターの製造方法
|
WO2002070719A2
(en)
|
2001-01-19 |
2002-09-12 |
Trustees Of The University Of Pennsylvania |
Regulatable gene expression system
|
US7588757B2
(en)
|
2001-03-14 |
2009-09-15 |
Genzyme Corporation |
Methods of treating Parkinson's disease using recombinant adeno-associated virus virions
|
WO2002071843A1
(en)
|
2001-03-14 |
2002-09-19 |
Genteric, Inc. |
Recombinant adeno-assocaited virus-mediated gene transfer via retroductal infusion of virions
|
US6841357B1
(en)
|
2001-03-30 |
2005-01-11 |
Stratagene California |
Method and kits for titering adeno-associated virus vectors
|
US7182944B2
(en)
|
2001-04-25 |
2007-02-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
Methods of increasing distribution of nucleic acids
|
US20030096264A1
(en)
|
2001-06-18 |
2003-05-22 |
Psychiatric Genomics, Inc. |
Multi-parameter high throughput screening assays (MPHTS)
|
US20040136963A1
(en)
|
2001-06-22 |
2004-07-15 |
The Trustees Of The University Of Pennsylvania |
Simian adenovirus vectors and methods of use
|
EP1409748B1
(en)
|
2001-06-22 |
2011-10-26 |
The Trustees of The University of Pennsylvania |
Recombinant Adenoviruses comprising simian adenovirus proteins and uses thereof.
|
US8241622B2
(en)
|
2001-07-13 |
2012-08-14 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors with intravector heterologous terminal palindromic sequences
|
EP1279740A1
(en)
|
2001-07-26 |
2003-01-29 |
Vrije Universiteit Brussel |
Recombinant vector derived from adeno-associated virus for gene therapy
|
US7319002B2
(en)
|
2001-08-08 |
2008-01-15 |
The Trustees Of The University Of Pennsylvania |
Method for purification of viral vectors having proteins which bind sialic acid
|
US20030092161A1
(en)
|
2001-09-19 |
2003-05-15 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for production of recombinant viruses, and uses therefor
|
US6723551B2
(en)
|
2001-11-09 |
2004-04-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Production of adeno-associated virus in insect cells
|
AU2002360355B2
(en)
|
2001-11-09 |
2005-07-07 |
Government Of The United States Of America, Department Of Health And Human Services |
Production of adeno-associated virus in insect cells
|
NZ578982A
(en)
|
2001-11-13 |
2011-03-31 |
Univ Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
|
EP1944043A1
(en)
|
2001-11-21 |
2008-07-16 |
The Trustees of the University of Pennsylvania |
Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
|
CA2852277C
(en)
|
2001-11-21 |
2018-02-20 |
Guangping Gao |
Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
|
CA2469623C
(en)
|
2001-12-12 |
2012-05-29 |
F H Faulding & Co Limited |
Composition for the preservation of viruses
|
ES2717377T3
(es)
|
2001-12-17 |
2019-06-20 |
Univ Pennsylvania |
Secuencias de serotipo 8 de virus adeno-asociado (AAV), vectores que las contienen y usos de las mismas
|
EP3339430A1
(en)
|
2001-12-17 |
2018-06-27 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses thereof
|
EP1463530A4
(en)
|
2001-12-19 |
2006-09-06 |
Lijun Wang |
ADENO-ASSOCIATED VIRUS-RELATED DELIVERY OF GDNF TO SKELETAL MUSCLES
|
CN1617938A
(zh)
|
2002-01-16 |
2005-05-18 |
戴诺生物技术有限公司 |
从单个样品中分离核酸和蛋白质的方法
|
EP1504108B1
(en)
|
2002-02-01 |
2013-04-17 |
Oxford Biomedica (UK) Limited |
Lentiviral vector
|
GB0208390D0
(en)
|
2002-04-11 |
2002-05-22 |
Univ London |
Adeno-associated virus producer system
|
US20030198620A1
(en)
|
2002-04-16 |
2003-10-23 |
Keiya Ozawa |
Method of treating amino acid metabolic disorders using recombinant adeno-associated virus virions
|
AU2003231031A1
(en)
|
2002-04-29 |
2003-11-17 |
The Trustees Of The University Of Pennsylvania |
Method for direct rescue and amplification of integrated viruses from cellular dna of tissues
|
MXPA04010603A
(es)
|
2002-04-30 |
2004-12-13 |
Oncolytics Biotech Inc |
Metodos mejorados de purificacion viral.
|
WO2004027019A2
(en)
|
2002-05-01 |
2004-04-01 |
University Of Florida Research Foundation, Inc. |
Improved raav expression systems for genetic modification of specific capsid proteins
|
AU2003229060A1
(en)
|
2002-05-14 |
2003-12-02 |
Merck And Co., Inc. |
Methods of adenovirus purification
|
US7419817B2
(en)
|
2002-05-17 |
2008-09-02 |
The United States Of America As Represented By The Secretary Department Of Health And Human Services, Nih. |
Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography
|
AU2003274397A1
(en)
|
2002-06-05 |
2003-12-22 |
University Of Florida |
Production of pseudotyped recombinant aav virions
|
EP2801614B1
(en)
|
2002-08-29 |
2019-05-15 |
The Board of Trustees of the Leland Stanford Junior University |
Circular nucleic acid vectors and methods for making and using the same
|
TW200509968A
(en)
|
2002-11-01 |
2005-03-16 |
Elan Pharm Inc |
Prevention and treatment of synucleinopathic disease
|
EP1418185A1
(en)
|
2002-11-11 |
2004-05-12 |
Aventis Pharma Deutschland GmbH |
Use of EDG2 receptor in an animal model of heart failure
|
US7169612B2
(en)
|
2002-11-11 |
2007-01-30 |
Sanofi-Aventis Deutschland Gmbh |
Use of EDG2 receptor in an animal model of heart failure
|
WO2004075861A2
(en)
|
2003-02-26 |
2004-09-10 |
Children's Hospital, Inc. |
Recombinant adeno-associated virus production
|
US20070172460A1
(en)
|
2003-03-19 |
2007-07-26 |
Jurgen Kleinschmidt |
Random peptide library displayed on aav vectors
|
WO2004108922A2
(en)
|
2003-04-25 |
2004-12-16 |
The Trustees Of The University Of Pennsylvania |
Use of aav comprising a capsid protein from aav7 or aav8 for the delivery of genes encoding apoprotein a or e genes to the liver
|
US8927269B2
(en)
|
2003-05-19 |
2015-01-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Avian adenoassociated virus and uses thereof
|
PL2277996T3
(pl)
|
2003-05-21 |
2015-03-31 |
Genzyme Corp |
Sposoby wytwarzania preparatów rekombinowanych wirionów AAV zasadniczo niezawierających pustych kapsydów
|
EP1486567A1
(en)
|
2003-06-11 |
2004-12-15 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Improved adeno-associated virus (AAV) vector for gene therapy
|
JP4888876B2
(ja)
|
2003-06-13 |
2012-02-29 |
田平 武 |
アルツハイマー病の治療のための組換えアデノ随伴ウィルスベクター
|
PT3235827T
(pt)
|
2003-06-19 |
2021-04-09 |
Genzyme Corp |
Viriões aav com imunorreatividade diminuída e seus usos
|
EP1636370B1
(en)
|
2003-06-20 |
2014-04-16 |
The Trustees of The University of Pennsylvania |
Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses
|
US7291498B2
(en)
|
2003-06-20 |
2007-11-06 |
The Trustees Of The University Of Pennsylvania |
Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
WO2005012537A2
(en)
|
2003-07-25 |
2005-02-10 |
Genvec, Inc. |
Adenoviral vector-based vaccines
|
WO2005013901A2
(en)
|
2003-07-31 |
2005-02-17 |
Isis Pharmaceuticals, Inc. |
Oligomeric compounds and compositions for use in modulation of small non-coding rnas
|
US20070073264A1
(en)
|
2003-09-26 |
2007-03-29 |
The Trustees Of The University Of Pennsylvania |
Methods, compositions and apparatus for delivering heterologous molecules to cells
|
EP3910063A1
(en)
|
2003-09-30 |
2021-11-17 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
US20060239966A1
(en)
*
|
2003-10-20 |
2006-10-26 |
Tornoee Jens |
In vivo gene therapy of parkinson's disease
|
US8394386B2
(en)
|
2004-04-28 |
2013-03-12 |
The Trustees Of The University Of Pennsylvania |
Sequential delivery of immunogenic molecules via adenovirus and adeno-associated virus-mediated administrations
|
WO2005116224A2
(en)
*
|
2004-05-18 |
2005-12-08 |
Children's Memorial Hospital |
Tetracycline-regulated adeno-associated viral (aav) vectors for gene delivery to the nervous system
|
JP2008501339A
(ja)
|
2004-06-01 |
2008-01-24 |
ジェンザイム・コーポレイション |
Aavベクターの凝集を防ぐための組成物およびその方法
|
ES2531425T3
(es)
|
2004-10-05 |
2015-03-13 |
Genzyme Corp |
Cánula escalonada
|
US7901921B2
(en)
|
2004-10-22 |
2011-03-08 |
Oncolytics Biotech Inc. |
Viral purification methods
|
CN1286981C
(zh)
|
2004-11-30 |
2006-11-29 |
华中科技大学同济医学院附属同济医院 |
表达人类cyp2j2反义基因的重组腺相关病毒及其制备方法
|
WO2006063247A2
(en)
|
2004-12-09 |
2006-06-15 |
Genzyme Corporation |
Regulated expression of transgenes in the central nervous system of mammals
|
US8614101B2
(en)
|
2008-05-20 |
2013-12-24 |
Rapid Pathogen Screening, Inc. |
In situ lysis of cells in lateral flow immunoassays
|
US7625570B1
(en)
|
2005-03-10 |
2009-12-01 |
The Regents Of The University Of California |
Methods for purifying adeno-associated virus
|
WO2006102072A2
(en)
|
2005-03-23 |
2006-09-28 |
The Trustees Of The University Of Pennsylvania |
Use of a pa131 polypeptide in treatment of atherosclerosis
|
EP2359865B1
(en)
|
2005-04-07 |
2013-10-02 |
The Trustees of The University of Pennsylvania |
Method of increasing the function of an AAV vector
|
WO2006119432A2
(en)
|
2005-04-29 |
2006-11-09 |
The Government Of The U.S.A., As Rep. By The Sec., Dept. Of Health & Human Services |
Isolation, cloning and characterization of new adeno-associated virus (aav) serotypes
|
PL2420256T3
(pl)
|
2005-05-02 |
2016-12-30 |
|
Terapia genowa dla zaburzeń neurometabolicznych
|
CA2619882C
(en)
|
2005-08-23 |
2015-05-26 |
The Regents Of The University Of California |
Reflux resistant cannula and system for chronic delivery of therapeutic agents using convection-enhanced delivery
|
ES2937245T3
(es)
|
2005-08-23 |
2023-03-27 |
Univ Pennsylvania |
ARN que contiene nucleósidos modificados y métodos de uso del mismo
|
EP1857552A1
(en)
|
2006-05-20 |
2007-11-21 |
Cargill Incorporated |
Thermostable xylose isomerase enzyme
|
PL1945779T3
(pl)
|
2005-10-20 |
2013-08-30 |
Uniqure Ip Bv |
Ulepszone wektory AAV produkowane w komórkach owadzich
|
US9150882B2
(en)
|
2006-01-31 |
2015-10-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Self-complementary parvoviral vectors, and methods for making and using the same
|
US7588772B2
(en)
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
SI2019683T2
(sl)
|
2006-04-25 |
2022-10-28 |
The Regents Of The University Of California |
Dajanje rastnih faktorjev za zdravljenje motenj CŽS
|
JP2009535339A
(ja)
|
2006-04-28 |
2009-10-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
低下されたキャプシド免疫原性を有する改変aavベクターおよびその使用
|
EP2018421B1
(en)
|
2006-04-28 |
2012-12-19 |
The Trustees of the University of Pennsylvania |
Scalable production method for aav
|
EP2012822B1
(en)
|
2006-04-28 |
2010-01-20 |
The Trustees of the University of Pennsylvania |
Modified adenovirus hexon protein and uses thereof
|
WO2007130519A2
(en)
|
2006-05-02 |
2007-11-15 |
Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services |
Viral nucleic acid microarray and method of use
|
WO2007139982A2
(en)
|
2006-05-25 |
2007-12-06 |
Sangamo Biosciences, Inc. |
Methods and compositions for gene inactivation
|
DK2687223T3
(en)
|
2006-05-30 |
2017-10-23 |
Mayo Foundation |
Detection and treatment of dementia
|
HUE044182T2
(hu)
|
2006-06-07 |
2019-10-28 |
Genzyme Corp |
Génterápia amiotrófiás laterális szklerózis és más gerincvelõ-rendellenességek kezelésére
|
EP2037892B1
(en)
|
2006-06-19 |
2015-03-18 |
Asklepios Biopharmaceutical, Inc. |
Modified factor viii and factor ix genes and vectors for gene therapy
|
CA2921594A1
(en)
|
2006-06-21 |
2007-12-27 |
Uniqure Ip B.V. |
Aav vectors with improved rep coding sequences for production in insect cells
|
DK2048955T3
(da)
|
2006-07-21 |
2013-09-02 |
California Inst Of Techn |
Målrettet gen-tilførsel til dendrit-cellevaccination
|
CN101522903B
(zh)
|
2006-08-24 |
2013-07-31 |
威洛克有限公司 |
具有重叠开放阅读框的基因在昆虫细胞中的表达及其方法和组合物
|
EP2097095B1
(en)
|
2006-11-29 |
2016-01-27 |
Nationwide Children's Hospital |
Myostatin inhibition for enhancing muscle and/or improving muscle function
|
AU2008214337B2
(en)
|
2007-02-02 |
2012-07-05 |
Biogen Ma Inc. |
Use of semaphorin 6A for promoting myelination and oligodendrocyte differentiation
|
US20120322861A1
(en)
|
2007-02-23 |
2012-12-20 |
Barry John Byrne |
Compositions and Methods for Treating Diseases
|
EP2191001B1
(en)
|
2007-04-09 |
2016-06-08 |
University of Florida Research Foundation, Inc. |
Raav vector compositions having tyrosine-modified capsid proteins and methods for use
|
US9611302B2
(en)
|
2007-04-09 |
2017-04-04 |
University Of Florida Research Foundation, Inc. |
High-transduction-efficiency RAAV vectors, compositions, and methods of use
|
US9725485B2
(en)
|
2012-05-15 |
2017-08-08 |
University Of Florida Research Foundation, Inc. |
AAV vectors with high transduction efficiency and uses thereof for gene therapy
|
WO2008128251A1
(en)
|
2007-04-17 |
2008-10-23 |
The Children's Hospital Of Philadelphia |
Humanized viral vectors and methods of use thereof
|
WO2008145400A2
(en)
|
2007-05-31 |
2008-12-04 |
Medigene Ag |
Mutated structural protein of a parvovirus
|
EP2012122A1
(en)
|
2007-07-06 |
2009-01-07 |
Medigene AG |
Mutated parvovirus structural proteins as vaccines
|
DK2158322T3
(en)
|
2007-06-06 |
2017-08-28 |
Genzyme Corp |
GENTERAPY AGAINST LYSOSOMAL STORAGE DISEASES
|
AU2008271658B8
(en)
|
2007-06-29 |
2013-07-04 |
F. Hoffmann-La Roche Ag |
Promoter
|
DK2176283T3
(en)
|
2007-07-14 |
2017-02-13 |
Univ Iowa Res Found |
METHODS AND COMPOSITIONS FOR TREATMENT OF BRAIN DISEASES
|
DK3093345T3
(da)
|
2007-07-26 |
2019-06-24 |
Uniqure Ip Bv |
Baculovirusvektorer omfattende gentagne kodende sekvenser med differentielle foretrukne kodoner
|
WO2009030025A1
(en)
|
2007-09-04 |
2009-03-12 |
Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health |
Porcine adeno-associated viruses
|
WO2009038462A1
(en)
|
2007-09-19 |
2009-03-26 |
Amsterdam Molecular Therapeutics B.V. |
Use of aav replication machinery for improved protein production
|
WO2009051421A2
(en)
|
2007-10-18 |
2009-04-23 |
Lg Electronics Inc. |
Method and system for transmitting and receiving signals
|
WO2009059192A1
(en)
|
2007-11-02 |
2009-05-07 |
Cornell University |
Materials and methods for gene mediated therapy of psychiatric disorders
|
LT2220242T
(lt)
|
2007-11-28 |
2017-04-10 |
The Trustees Of The University Of Pennsylvania |
Simian pošeimio b adenovirusai sadv-28,27,-29,-32,-33 ir -35 ir jų panaudojimas
|
DK2220241T3
(en)
|
2007-11-28 |
2017-01-09 |
Univ Pennsylvania |
Adenovirus comprising a simian adenovirus E-SAdV-39-capsidhexonprotein and uses thereof
|
MX2010005860A
(es)
|
2007-11-28 |
2010-06-22 |
Univ Pennsylvania |
Adenovirus simianos de la subfamilia c sadv-40, sadv-31 y sadv-34 y usos de los mismos.
|
CA2710398A1
(en)
|
2008-01-18 |
2009-10-15 |
Genentech, Inc. |
Methods and compositions for targeting polyubiquitin
|
DK2242840T3
(da)
|
2008-01-29 |
2019-10-21 |
Applied Genetic Tech Corporation |
Produktion af rekombinant adeno-associeret virus under anvendelse af bhk-celler i suspension
|
CA2715924C
(en)
|
2008-02-19 |
2021-01-12 |
Andrew Christian BAKKER |
Optimisation of expression of parvoviral rep and cap proteins in insect cells
|
CN102016011B
(zh)
|
2008-03-04 |
2013-12-11 |
宾夕法尼亚大学托管会 |
猿猴腺病毒sadv-36、-42.1、-42.2和-44及其应用
|
WO2009134681A2
(en)
|
2008-04-30 |
2009-11-05 |
The Trustees Of The University Of Pennsylvania |
Aav7 viral vectors for targeted delivery of rpe cells
|
WO2009137006A2
(en)
|
2008-04-30 |
2009-11-12 |
The University Of North Carolina At Chapel Hill |
Directed evolution and in vivo panning of virus vectors
|
AU2009274482A1
(en)
|
2008-05-20 |
2010-01-28 |
Eos Neuroscience, Inc. |
Vectors for delivery of light-sensitive proteins and methods of use
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
US20110171262A1
(en)
|
2008-06-17 |
2011-07-14 |
Andrew Christian Bakker |
Parvoviral capsid with incorporated gly-ala repeat region
|
US8945885B2
(en)
|
2008-07-03 |
2015-02-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Minicircle DNA vector preparations and methods of making and using the same
|
WO2010036118A1
(en)
|
2008-09-29 |
2010-04-01 |
Amsterdam Molecular Therapeutics (Amt) B.V. |
Porphobilinogen deaminase gene therapy
|
DK2350269T3
(en)
|
2008-10-31 |
2015-12-07 |
Univ Pennsylvania |
ABE ADENOVIRUS WITH SADV-46 HEXONCAPSIDE PROTEINS AND APPLICATIONS THEREOF
|
EP2362912A1
(en)
|
2008-11-14 |
2011-09-07 |
Life Technologies Corporation |
Compositions and methods for engineering cells
|
US9415121B2
(en)
|
2008-12-19 |
2016-08-16 |
Nationwide Children's Hospital |
Delivery of MECP2 polynucleotide using recombinant AAV9
|
ES2634118T3
(es)
|
2009-02-11 |
2017-09-26 |
The University Of North Carolina At Chapel Hill |
Vectores de virus modificados y métodos para fabricar y utilizar los mismos
|
MX2011009193A
(es)
|
2009-03-04 |
2011-12-16 |
Deutsches Krebsforsch |
Proteina activadora del ensamblaje (aap) y su uso para la fabricacion de particulas de parvovirus que consisten esencialmente de vp3.
|
CA2756596A1
(en)
|
2009-03-27 |
2010-09-30 |
Proyecto De Biomedicina Cima, S.L. |
Methods and compositions for the treatment of cirrhosis and liver fibrosis
|
DK2425000T3
(da)
|
2009-04-30 |
2019-05-13 |
Univ Pennsylvania |
Sammensætninger rettet mod ledende luftvejsceller omfattende konstrukter af adeno-associeret virus
|
NZ595710A
(en)
|
2009-05-01 |
2013-10-25 |
Redbiotec Ag |
Recombinant virus-like particles encoded by multi-gene vector
|
JP5879256B2
(ja)
|
2009-05-02 |
2016-03-08 |
ジェンザイム・コーポレーション |
神経変性障害のための遺伝子治療
|
US8734809B2
(en)
|
2009-05-28 |
2014-05-27 |
University Of Massachusetts |
AAV's and uses thereof
|
US8476418B2
(en)
|
2009-05-28 |
2013-07-02 |
Deutsches Krebsforschungszentrum |
Modified AAV capsid polypeptides
|
WO2010138675A1
(en)
|
2009-05-29 |
2010-12-02 |
The Trustees Of The University Of Pennsylvania |
Simian adenovirus 41 and uses thereof
|
LT3067417T
(lt)
|
2009-06-16 |
2018-11-12 |
Genzyme Corporation |
Pagerinti rekombinantinių aav vektorių gryninimo būdai
|
BR112012000421A2
(pt)
|
2009-07-06 |
2019-09-24 |
Alnylam Pharmaceuticals Inc |
composições e métodos para intensificar a produção de um produto biológico.
|
EP2292781A1
(en)
|
2009-08-17 |
2011-03-09 |
Genethon |
Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions
|
WO2011038187A1
(en)
|
2009-09-25 |
2011-03-31 |
The Trustees Of The University Of Pennsylvania |
Controlled adeno-associated virus (aav) diversification and libraries prepared therefrom
|
KR20120089743A
(ko)
|
2009-11-09 |
2012-08-13 |
제네포드 테라퓨틱스 에이비 |
생체 내에서 최적화된 뉴런 특이적 연속 도파 합성을 위한 신규한 바이러스 벡터 구성물
|
WO2011069529A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Mannose-containing solution for lyophilization, transfection and/or injection of nucleic acids
|
US9169494B2
(en)
|
2010-01-12 |
2015-10-27 |
The University Of North Carolina At Chapel Hill |
Restrictive inverted terminal repeats for viral vectors
|
EP2528941A4
(en)
|
2010-01-25 |
2013-05-29 |
Univ New York |
RECOMBINANT BOTULINUM NEUROTOXIN DERIVATIVES MODIFIED FOR TRAFFIC STUDIES AND NEURONAL DELIVERY
|
CA2788682C
(en)
|
2010-02-05 |
2019-03-05 |
The University Of North Carolina At Chapel Hill |
Compositions and methods for enhanced parvovirus transduction
|
EP2545165B1
(en)
|
2010-03-11 |
2020-07-29 |
uniQure IP B.V. |
Mutated rep encoding sequences for use in aav production
|
US9546112B2
(en)
|
2010-03-22 |
2017-01-17 |
Association Institut De Myologie |
Methods of increasing efficiency of vector penetration of target tissue
|
MX342858B
(es)
|
2010-03-29 |
2016-10-13 |
The Trustees Of The Univ Of Pennsylvania * |
Sistema de ablacion transgenica inducida farmacologicamente.
|
US9315825B2
(en)
|
2010-03-29 |
2016-04-19 |
The Trustees Of The University Of Pennsylvania |
Pharmacologically induced transgene ablation system
|
WO2011122950A1
(en)
|
2010-04-01 |
2011-10-06 |
Amsterdam Molecular Therapeutics (Amt) Ip B.V. |
Monomeric duplex aav vectors
|
EP2561075B1
(en)
|
2010-04-23 |
2018-06-27 |
University of Massachusetts |
Aav-based treatment of cholesterol-related disorders
|
CA2833905C
(en)
|
2010-04-23 |
2019-09-10 |
University Of Massachusetts |
Multicistronic expression constructs
|
DK2561073T3
(en)
|
2010-04-23 |
2016-12-12 |
Univ Massachusetts |
Aav vectors targeted to central nervous system and methods of use thereof
|
US9839696B2
(en)
|
2010-04-30 |
2017-12-12 |
City Of Hope |
Recombinant adeno-associated vectors for targeted treatment
|
US8927514B2
(en)
|
2010-04-30 |
2015-01-06 |
City Of Hope |
Recombinant adeno-associated vectors for targeted treatment
|
CA3128549A1
(en)
|
2010-07-12 |
2012-01-19 |
Universitat Autonoma De Barcelona |
Gene therapy composition for use in diabetes treatment
|
US8808684B2
(en)
|
2010-09-10 |
2014-08-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Epidermal growth factor receptor (EGFR) and methods of use in adenoviral-associated virus type 6 (AAV6) transduction
|
KR101362111B1
(ko)
|
2010-10-05 |
2014-02-12 |
다카라 바이오 가부시키가이샤 |
바이러스 벡터의 제조방법
|
US8663624B2
(en)
|
2010-10-06 |
2014-03-04 |
The Regents Of The University Of California |
Adeno-associated virus virions with variant capsid and methods of use thereof
|
US9175280B2
(en)
|
2010-10-12 |
2015-11-03 |
Sangamo Biosciences, Inc. |
Methods and compositions for treating hemophilia B
|
CN103189507A
(zh)
*
|
2010-10-27 |
2013-07-03 |
学校法人自治医科大学 |
用于向神经系统细胞导入基因的腺相关病毒粒子
|
US9116157B2
(en)
|
2010-11-05 |
2015-08-25 |
Brandeis University |
Ice-cleaved alpha-synuclein as a biomarker
|
WO2012064920A1
(en)
|
2010-11-11 |
2012-05-18 |
University Of Miami |
Methods, compositions, cells, and kits for treating ischemic injury
|
AU2011332025B2
(en)
|
2010-11-23 |
2015-06-25 |
The Trustees Of The University Of Pennsylvania |
Subfamily E simian adenoviruses A1321, A1325, A1295, A1309 and A1322 and uses thereof
|
JP6042825B2
(ja)
*
|
2011-02-10 |
2016-12-14 |
ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
改変された形質導入プロファイルを有するウイルスベクターならびにその製造および使用の方法
|
JP6224459B2
(ja)
|
2011-02-17 |
2017-11-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組織特異性を改変し、aav9媒介遺伝子導入を改善するための組成物および方法
|
EP2678433B1
(en)
*
|
2011-02-22 |
2017-05-03 |
California Institute of Technology |
Delivery of proteins using adeno-associated virus (aav) vectors
|
GB201103062D0
(en)
|
2011-02-22 |
2011-04-06 |
Isis Innovation |
Method
|
US20120220648A1
(en)
*
|
2011-02-24 |
2012-08-30 |
National Taiwan University Hospital |
Method of Treating Aromatic L-Amino Acid Decarboxylase (AADC) Deficiency Using Adeno-Associated Virus (AAV)-AADC Vector
|
EP2500434A1
(en)
|
2011-03-12 |
2012-09-19 |
Association Institut de Myologie |
Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
|
JP6007463B2
(ja)
|
2011-04-18 |
2016-10-12 |
国立研究開発法人国立精神・神経医療研究センター |
薬剤送達粒子及びその製造方法
|
WO2012145572A1
(en)
|
2011-04-20 |
2012-10-26 |
The Trustees Of The University Of Pennsylvania |
Regimens and compositions for aav-mediated passive immunization of airborne pathogens
|
AU2012245328B2
(en)
|
2011-04-22 |
2016-09-29 |
The Regents Of The University Of California |
Adeno-associated virus virions with variant capsid and methods of use thereof
|
US9249425B2
(en)
|
2011-05-16 |
2016-02-02 |
The Trustees Of The University Of Pennslyvania |
Proviral plasmids and production of recombinant adeno-associated virus
|
US9598468B2
(en)
|
2011-05-18 |
2017-03-21 |
University Of Florida Research Foundation, Incorporated |
Polypeptides and vectors for targeting HER2/neu expressing cells and uses thereof
|
US20120295960A1
(en)
*
|
2011-05-20 |
2012-11-22 |
Oxford Biomedica (Uk) Ltd. |
Treatment regimen for parkinson's disease
|
KR20140023326A
(ko)
|
2011-06-06 |
2014-02-26 |
비오까르띠 에스아 |
이온성 계면활성제에 의한 세포의 선택적 용해
|
EP2737071B1
(en)
|
2011-07-27 |
2017-03-15 |
Genethon |
Improved baculovirus expression systems
|
CN107502597A
(zh)
|
2011-09-08 |
2017-12-22 |
尤尼克尔Ip股份有限公司 |
从aav制剂中去除污染病毒
|
US9056892B2
(en)
|
2011-09-09 |
2015-06-16 |
University Of Washington |
Retrograde transport peptide and use of same for delivery to central nervous system
|
GB201118636D0
(en)
|
2011-10-28 |
2011-12-07 |
Oxford Biomedica Ltd |
Nucleotide sequence
|
ES2609860T3
(es)
|
2011-10-28 |
2017-04-24 |
The University Of North Carolina At Chapel Hill |
Línea celular para la producción de virus adenoasociado
|
AU2012340567B2
(en)
|
2011-11-22 |
2017-11-23 |
The Children's Hospital Of Philadelphia |
Virus vectors for highly efficient transgene delivery
|
WO2013078316A1
(en)
|
2011-11-23 |
2013-05-30 |
Nationwide Children's Hospital, Inc. |
Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides
|
WO2013078199A2
(en)
|
2011-11-23 |
2013-05-30 |
Children's Medical Center Corporation |
Methods for enhanced in vivo delivery of synthetic, modified rnas
|
WO2013103896A1
(en)
|
2012-01-06 |
2013-07-11 |
Mayo Foundation For Medical Education And Research |
Treating cardiovascular or renal diseases
|
PT2814513T
(pt)
|
2012-02-14 |
2018-03-02 |
Univ California |
Entrega sistémica e expressão regulada de genes parácrinos para doenças cardiovasculares e outras doenças
|
EP2814958B1
(en)
|
2012-02-17 |
2019-08-07 |
The Children's Hospital of Philadelphia |
Aav vector compositions and methods for gene transfer to cells, organs and tissues
|
PL2839014T3
(pl)
|
2012-04-18 |
2021-08-23 |
The Children's Hospital Of Philadelphia |
Kompozycja i sposoby na wysoko wydajny transfer genu za pomocą kapsydu wariantów aav
|
EP2660325A3
(en)
|
2012-05-02 |
2014-02-12 |
Christian Medical College |
AAV vectors and corresponding nucleotide sequences and methods
|
US9163259B2
(en)
|
2012-05-04 |
2015-10-20 |
Novartis Ag |
Viral vectors for the treatment of retinal dystrophy
|
AU2013259892B2
(en)
|
2012-05-08 |
2017-09-14 |
Alectos Therapeutics Inc. |
Permeable glycosidase inhibitors and uses thereof
|
EP2847337A4
(en)
|
2012-05-09 |
2016-04-27 |
Univ Oregon Health & Science |
PLASMIDS AND VIRAL VECTORS ASSOCIATED WITH ADENOVIRUS
|
TWI698240B
(zh)
|
2012-05-15 |
2020-07-11 |
澳大利亞商艾佛蘭屈澳洲私營有限公司 |
使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd)
|
US10294281B2
(en)
|
2012-05-15 |
2019-05-21 |
University Of Florida Research Foundation, Incorporated |
High-transduction-efficiency rAAV vectors, compositions, and methods of use
|
SG11201407343XA
(en)
|
2012-05-18 |
2014-12-30 |
Univ Pennsylvania |
Subfamily e simian adenoviruses a1302, a1320, a1331 and a1337 and uses thereof
|
BR112015000161A2
(pt)
|
2012-07-06 |
2017-06-27 |
Univ Iowa Res Found |
composições de vetor de vírus adeno-associado modificado
|
US9422576B2
(en)
|
2012-07-06 |
2016-08-23 |
Takara Bio Inc. |
Cell capable of producing adeno-associated virus vector
|
US20150252384A1
(en)
|
2012-08-01 |
2015-09-10 |
National Children's Hospital |
Intrathecal delivery of recombinant adeno-associated virus 9
|
CA2882763C
(en)
|
2012-08-31 |
2019-01-15 |
The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Aav mediated aquaporin gene transer to treat sjogren's syndrome
|
CN104797593B
(zh)
|
2012-09-28 |
2020-05-08 |
北卡罗来纳-查佩尔山大学 |
靶向少突胶质细胞的aav载体
|
SG10201912328UA
(en)
|
2012-12-12 |
2020-02-27 |
Broad Inst Inc |
Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Therapeutic Applications
|
WO2014103957A1
(ja)
|
2012-12-25 |
2014-07-03 |
タカラバイオ株式会社 |
Aav変異体
|
DK2943567T3
(en)
|
2013-01-08 |
2018-01-02 |
Genzyme Corp |
USE OF INOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE
|
US9066966B2
(en)
|
2013-02-01 |
2015-06-30 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods and pharmaceutical compositions for the treatment of cardiomyopathy due to friedreich ataxia
|
EP2954051B1
(en)
|
2013-02-08 |
2019-03-27 |
The Trustees Of The University Of Pennsylvania |
Modified aav8 capsid for gene transfer for retinal therapies
|
AU2014244167A1
(en)
|
2013-03-13 |
2015-10-08 |
The Children's Hospital Of Philadelphia |
Adeno-associated virus vectors and methods of use thereof
|
WO2014143932A1
(en)
|
2013-03-15 |
2014-09-18 |
The University Of North Carolina At Chapel Hill |
Synthetic adeno-associated virus inverted terminal repeats
|
JP2016517278A
(ja)
|
2013-03-15 |
2016-06-16 |
ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia |
スタッファー/フィラーポリヌクレオチド配列を含むベクターおよびその使用方法
|
CA2909085C
(en)
|
2013-04-08 |
2023-08-29 |
University Of Iowa Research Foundation |
Chimeric adeno-associated virus/ bocavirus parvovirus vector
|
EP2792742A1
(en)
|
2013-04-17 |
2014-10-22 |
Universitätsklinikum Hamburg-Eppendorf (UKE) |
Gene-therapy vectors for treating cardiomyopathy
|
MX365711B
(es)
|
2013-04-18 |
2019-06-11 |
Fond Telethon |
Administración efectiva de genes grandes por vectores aav duales.
|
MX2015014712A
(es)
|
2013-04-20 |
2016-04-27 |
Res Inst Nationwide Childrens Hospital |
Administración de virus adeno-asociado recombinante de construcciones de polinucléotidos u7snrna dirigida al exon 2.
|
WO2015012924A2
(en)
|
2013-04-29 |
2015-01-29 |
The Trustees Of The University Of Pennsylvania |
Tissue preferential codon modified expression cassettes, vectors containing same, and use thereof
|
CA3209821A1
(en)
|
2013-05-15 |
2014-11-20 |
Regents Of The University Of Minnesota |
Adeno-associated virus mediated gene transfer to the central nervous system
|
WO2014186746A1
(en)
|
2013-05-16 |
2014-11-20 |
University Of Florida Research Foundation, Inc. |
HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN TRANSLATION
|
WO2014194132A1
(en)
|
2013-05-31 |
2014-12-04 |
The Regents Of The University Of California |
Adeno-associated virus variants and methods of use thereof
|
WO2014201308A1
(en)
|
2013-06-12 |
2014-12-18 |
Washington University |
Endothelial-targeted adenoviral vectors, methods and uses therefor
|
WO2014201252A2
(en)
|
2013-06-13 |
2014-12-18 |
Shire Human Genetic Therapies, Inc. |
Messenger rna based viral production
|
CN105579465B
(zh)
|
2013-07-22 |
2019-09-10 |
费城儿童医院 |
用于基因转移到细胞、器官和组织中的变异aav和组合物、方法及用途
|
EP3024497B1
(en)
|
2013-07-26 |
2021-01-13 |
University of Iowa Research Foundation |
Methods and compositions for treating brain diseases
|
ITTO20130669A1
(it)
|
2013-08-05 |
2015-02-06 |
Consiglio Nazionale Ricerche |
Vettore adeno-associato ricombinante muscolo-specifico e suo impiego nel trattamento di patologie muscolari
|
EP3039129B1
(en)
|
2013-08-30 |
2018-06-27 |
Amgen Inc. |
High titer recombinant aav vector production in adherent and suspension cells
|
EP3770169A1
(en)
|
2013-09-12 |
2021-01-27 |
BioMarin Pharmaceutical Inc. |
Adeno-associated virus factor viii vectors
|
EP3564379A1
(en)
|
2013-09-13 |
2019-11-06 |
California Institute of Technology |
Selective recovery
|
WO2015044292A1
(en)
|
2013-09-26 |
2015-04-02 |
Universitat Autonoma De Barcelona |
Gene therapy compositions for use in the prevention and/or treatment of non-alcoholic fatty liver disease
|
JP6985795B2
(ja)
|
2013-09-26 |
2021-12-22 |
ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド |
標的遺伝子治療のための合成コンビナトリアルaavカプシドライブラリー
|
NZ718926A
(en)
|
2013-10-11 |
2021-12-24 |
Massachusetts Eye & Ear Infirmary |
Methods of predicting ancestral virus sequences and uses thereof
|
US20160243260A1
(en)
|
2013-10-24 |
2016-08-25 |
Uniqure Ip B.V. |
Treatment of neurological diseases using adeno-associated virus (AAV) comprising AAV-5 capsid proteins
|
EP3066195A4
(en)
|
2013-11-08 |
2017-06-28 |
The Board of Trustees of the University of Arkansas |
Adeno-associated virus "x" oncogene
|
MX2016006774A
(es)
|
2013-11-26 |
2016-10-13 |
Us Health |
Vectores de virus adeno-asociado para el tratamiento de la enfermedad de almacenamiento de glucogeno.
|
CN105765066B
(zh)
|
2013-11-29 |
2018-12-14 |
宝生物工程株式会社 |
用于定量腺伴随病毒的方法
|
EP3080269B1
(en)
|
2013-12-09 |
2019-05-22 |
Baylor College of Medicine |
Hippo and dystrophin complex signaling in cardiomyocyte renewal
|
KR20160097331A
(ko)
|
2013-12-12 |
2016-08-17 |
더 브로드 인스티튜트, 인코퍼레이티드 |
뉴클레오티드 반복 장애에서의 crispr-cas 시스템의 조성물 및 방법 및 용도
|
GB201322798D0
(en)
|
2013-12-20 |
2014-02-05 |
Oxford Biomedica Ltd |
Production system
|
PL3092493T3
(pl)
|
2014-01-09 |
2019-09-30 |
Genethon |
Sposoby diagnozowania lub monitorowania dystrofii mięśniowych
|
US20150197809A1
(en)
|
2014-01-13 |
2015-07-16 |
Trustees Of Boston University |
Methods and assays relating to huntingtons disease and parkinson's disease
|
GB201401707D0
(en)
|
2014-01-31 |
2014-03-19 |
Sec Dep For Health The |
Adeno-associated viral vectors
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
WO2015124546A1
(en)
|
2014-02-19 |
2015-08-27 |
Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii- Cnic |
Aav vectors for the treatment of ischemic and non-ischemic heart disease
|
SG11201606824VA
(en)
|
2014-02-19 |
2016-09-29 |
Hoffmann La Roche |
Blood brain barrier shuttle
|
WO2015127128A2
(en)
|
2014-02-19 |
2015-08-27 |
University Of Massachusetts |
Recombinant aavs having useful transcytosis properties
|
WO2015126972A1
(en)
|
2014-02-21 |
2015-08-27 |
University Of Florida Research Foundation, Inc. |
Methods and compositions for gene delivery to on bipolar cells
|
US10272117B2
(en)
|
2014-02-24 |
2019-04-30 |
Celgene Corporation |
Methods of using an activator of cereblon for neural cell expansion and the treatment of central nervous system disorders
|
WO2015131076A1
(en)
|
2014-02-27 |
2015-09-03 |
Yale University |
Nlrp6 inflammasome intestinal epithelium mucus secretion
|
ES2768763T3
(es)
|
2014-03-04 |
2020-06-23 |
Univ Florida |
Vectores rAAV mejorados y métodos para la transducción de fotorreceptores y células EPR
|
CA2941357A1
(en)
|
2014-03-07 |
2015-09-11 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Non-narcotic crmp2 peptides targeting sodium channels for chronic pain
|
BR112016020688B1
(pt)
|
2014-03-09 |
2024-01-30 |
The Trustees Of The University Of Pennsylvania |
Vetores virais recombinantes, vírus adenoassociado recombinante, composição farmacêutica, bem como uso dos mesmos
|
BR112016020783A2
(pt)
|
2014-03-10 |
2017-10-03 |
Uniqure Ip Bv |
Vetores de aav adicionalmente melhorados produzidos em células de inseto
|
EP3129485B2
(en)
|
2014-04-09 |
2022-12-21 |
Editas Medicine, Inc. |
Crispr/cas-related methods and compositions for treating cystic fibrosis
|
EP2933335A1
(en)
|
2014-04-18 |
2015-10-21 |
Genethon |
A method of treating peripheral neuropathies and motor neuron diseases
|
CA2946392A1
(en)
|
2014-04-25 |
2015-10-29 |
James M. Wilson |
Ldlr variants and their use in compositions for reducing cholesterol levels
|
WO2015164786A1
(en)
|
2014-04-25 |
2015-10-29 |
University Of Massachusetts |
Recombinant aav vectors useful for reducing immunity against transgene products
|
WO2015173436A1
(en)
|
2014-05-16 |
2015-11-19 |
Vrije Universiteit Brussel |
Genetic correction of myotonic dystrophy type 1
|
WO2015191508A1
(en)
|
2014-06-09 |
2015-12-17 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
WO2015192063A1
(en)
|
2014-06-13 |
2015-12-17 |
Yasuhiro Ikeda |
Methods and materials for increasing viral vector infectivity
|
WO2015196179A1
(en)
|
2014-06-20 |
2015-12-23 |
University Of Florida Research Foundation, Inc. |
Methods of packaging multiple adeno-associated virus vectors
|
EP2960336A1
(en)
|
2014-06-27 |
2015-12-30 |
Genethon |
Efficient systemic treatment of dystrophic muscle pathologies
|
US10526583B2
(en)
|
2014-07-02 |
2020-01-07 |
University Of Florida Research Foundation, Incorporated |
Compositions and methods for purifying recombinant adeno-associated virus
|
US10023846B2
(en)
|
2014-07-10 |
2018-07-17 |
Takara Bio Inc. |
Production method for non-enveloped virus particles
|
US9616090B2
(en)
|
2014-07-30 |
2017-04-11 |
Sangamo Biosciences, Inc. |
Gene correction of SCID-related genes in hematopoietic stem and progenitor cells
|
WO2016019364A1
(en)
|
2014-08-01 |
2016-02-04 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for self-regulated inducible gene expression
|
JP6842410B2
(ja)
|
2014-10-03 |
2021-03-17 |
ユニバーシティ オブ マサチューセッツ |
新規の高効率ライブラリーにより同定されるaavベクター
|
US10370432B2
(en)
|
2014-10-03 |
2019-08-06 |
University Of Massachusetts |
Heterologous targeting peptide grafted AAVS
|
US10842886B2
(en)
|
2014-10-10 |
2020-11-24 |
Research Institute At Nationwide Children's Hospital |
Guided injections for AAV gene transfer to muscle
|
JP7023108B2
(ja)
|
2014-10-21 |
2022-02-21 |
ユニバーシティ オブ マサチューセッツ |
組み換えaavバリアントおよびその使用
|
AU2015342997B2
(en)
|
2014-11-05 |
2021-11-18 |
Research Institute At Nationwide Children's Hospital |
Methods and materials for producing recombinant viruses in eukaryotic microalgae
|
CA2966620A1
(en)
|
2014-11-05 |
2016-05-12 |
Voyager Therapeutics, Inc. |
Aadc polynucleotides for the treatment of parkinson's disease
|
RU2730668C2
(ru)
|
2014-11-19 |
2020-08-24 |
Аксон Ньюросайенс Се |
Гуманизированные тау-антитела при болезни альцгеймера
|
WO2016081927A2
(en)
|
2014-11-21 |
2016-05-26 |
University Of Florida Research Foundation, Inc. |
Genome-modified recombinant adeno-associated virus vectors
|
EP3221453A4
(en)
|
2014-11-21 |
2018-09-12 |
The University of North Carolina at Chapel Hill |
Aav vectors targeted to the central nervous system
|
FI3224376T4
(fi)
|
2014-11-28 |
2023-08-31 |
|
Dna-epäpuhtaudet koostumuksessa, joka käsittää parvovirusvirionin
|
EP3230441A4
(en)
|
2014-12-12 |
2018-10-03 |
Voyager Therapeutics, Inc. |
Compositions and methods for the production of scaav
|
CA3221229A1
(en)
|
2015-01-14 |
2016-07-21 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for targeted gene transfer
|
JP2018506530A
(ja)
|
2015-01-30 |
2018-03-08 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
脊柱軟膜下遺伝子送達システム
|
WO2016126857A1
(en)
|
2015-02-03 |
2016-08-11 |
University Of Florida Research Foundation, Inc. |
Recombinant aav1, aav5, and aav6 capsid mutants and uses thereof
|
EP4219728A3
(en)
|
2015-02-10 |
2023-08-23 |
Genzyme Corporation |
Enhanced delivery of viral particles to the striatum and cortex
|
WO2016137949A1
(en)
|
2015-02-23 |
2016-09-01 |
Voyager Therapeutics, Inc. |
Regulatable expression using adeno-associated virus (aav)
|
EP3268024B1
(en)
|
2015-03-10 |
2020-09-09 |
The Trustees of Columbia University in the City of New York |
Recombinant glut1 adeno-associated viral vector constructs and related methods for restoring glut1 expression
|
WO2016154055A1
(en)
|
2015-03-20 |
2016-09-29 |
Bluebird Bio, Inc. |
Vector formulations
|
JP6836999B2
(ja)
|
2015-03-24 |
2021-03-03 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California |
アデノ随伴ウイルス変異体及びその使用方法
|
WO2016161388A1
(en)
|
2015-04-03 |
2016-10-06 |
University Of Massachusetts |
Fully stabilized asymmetric sirna
|
US10081659B2
(en)
|
2015-04-06 |
2018-09-25 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Adeno-associated vectors for enhanced transduction and reduced immunogenicity
|
TWI707951B
(zh)
|
2015-04-08 |
2020-10-21 |
美商健臻公司 |
過大腺相關載體之製造
|
ES2763551T3
(es)
|
2015-04-16 |
2020-05-29 |
Univ Emory |
Promotores y vectores recombinantes para la expresión de proteínas en el hígado y uso de los mismos
|
WO2016172155A1
(en)
|
2015-04-23 |
2016-10-27 |
University Of Massachusetts |
Modulation of aav vector transgene expression
|
WO2016172008A1
(en)
|
2015-04-24 |
2016-10-27 |
University Of Massachusetts |
Modified aav constructions and uses thereof
|
WO2016179038A1
(en)
|
2015-05-01 |
2016-11-10 |
Spark Therapeutics, Inc. |
ADENO-ASSOCIATED VIRUS-MEDIATED CRISPR-Cas9 TREATMENT OF OCULAR DISEASE
|
WO2016179496A1
(en)
|
2015-05-07 |
2016-11-10 |
Massachusetts Eye And Ear Infirmary |
Methods of delivering an agent to the eye
|
CN107735140B
(zh)
|
2015-05-11 |
2021-04-20 |
亚克安娜生命科学有限公司 |
药物输送系统和方法
|
US11447797B2
(en)
|
2015-05-12 |
2022-09-20 |
The United States Of America,As Represented By The Secretary, Department Of Health And Human Service |
AAV with unique capsid protein VP1 and methods of using for treatment
|
US20170067028A1
(en)
|
2015-05-15 |
2017-03-09 |
Douglas J. Ballon |
Radiolabeling of adeno associated virus
|
US10729790B2
(en)
|
2015-05-26 |
2020-08-04 |
Salk Institute For Biological Studies |
Motor neuron-specific expression vectors
|
JP6573991B2
(ja)
|
2015-05-28 |
2019-09-11 |
コーネル ユニヴァーシティー |
血管性浮腫の治療としてのc1eiのアデノ随伴ウイルス介在性送達
|
WO2016196507A1
(en)
|
2015-05-29 |
2016-12-08 |
University Of Iowa Research Foundation |
Methods of delivery of transgenes for treating brain diseases
|
US11542500B2
(en)
|
2015-05-29 |
2023-01-03 |
The Trustees Of The University Of Pennsylvania |
TRIM11 for degradation of protein aggregates
|
IL256517B1
(en)
|
2015-06-23 |
2024-02-01 |
Childrens Hospital Philadelphia |
Modified factor IX, and preparations, methods and uses for gene transfer to cells, organs and tissues
|
US11266748B2
(en)
|
2015-07-02 |
2022-03-08 |
University Of Florida Research Foundation, Incorporated |
Recombinant adeno-associated virus vectors to target medullary thyroid carcinoma
|
US20170007669A1
(en)
|
2015-07-07 |
2017-01-12 |
Mayo Foundation For Medical Education And Research |
Peptide-mediated delivery of active agents across the blood-brain barrier
|
EP3320101B1
(en)
|
2015-07-07 |
2021-08-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for expressing a polynucleotide of interest in the peripheral nervous system of a subject
|
US20180216133A1
(en)
|
2015-07-17 |
2018-08-02 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for achieving high levels of transduction in human liver cells
|
CA2988471A1
(en)
|
2015-07-28 |
2017-02-02 |
University Of Massachusetts |
Transgenic expression of dnase i in vivo delivered by an adeno-associated virus vector
|
US10738087B2
(en)
|
2015-07-30 |
2020-08-11 |
Massachusetts Eye And Ear Infirmary |
Ancestral virus sequences and uses thereof
|
US20190000940A1
(en)
|
2015-07-31 |
2019-01-03 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of aadc deficiency
|
WO2017024198A1
(en)
|
2015-08-06 |
2017-02-09 |
The Trustees Of The University Of Pennsylvania |
Glp-1 and use thereof in compositions for treating metabolic diseases
|
CN108778323A
(zh)
|
2015-09-24 |
2018-11-09 |
生物马林药物股份有限公司 |
腺相关病毒因子viii载体、相关病毒粒子以及包含其的治疗配制品
|
SG10202107733QA
(en)
|
2015-09-28 |
2021-09-29 |
Univ North Carolina Chapel Hill |
Methods and compositions for antibody-evading virus vectors
|
SG10202111233SA
(en)
|
2015-10-09 |
2021-11-29 |
Genzyme Corp |
Improved flare (flow cytometry attenuated reporter expression) technology for rapid bulk sorting
|
US10123969B2
(en)
|
2015-10-15 |
2018-11-13 |
Wisconsin Alumni Research Foundation |
Osmotic enhancement of drug/therapeutic delivery to the brain following infusion or injection into the cerebrospinal fluid
|
CA3002982A1
(en)
|
2015-10-22 |
2017-04-27 |
University Of Massachusetts |
Methods and compositions for treating metabolic imbalance in neurodegenerative disease
|
WO2017070476A2
(en)
|
2015-10-22 |
2017-04-27 |
University Of Florida Research Foundation, Inc. |
Synthetic combinatorial aav3 capsid library
|
CA3002980A1
(en)
|
2015-10-22 |
2017-04-27 |
University Of Massachusetts |
Prostate-targeting adeno-associated virus serotype vectors
|
BR112018008069A2
(pt)
|
2015-10-23 |
2018-11-13 |
Univ Iowa Res Found |
métodos de tratamento de doenças neurodegenerati-vas usando terapia gênica para retardar o início e progressão da doença ao mesmo tempo em que fornece proteção cognitiva
|
US20180230489A1
(en)
|
2015-10-28 |
2018-08-16 |
Voyager Therapeutics, Inc. |
Regulatable expression using adeno-associated virus (aav)
|
CN108779167A
(zh)
|
2015-10-28 |
2018-11-09 |
宾夕法尼亚州大学信托人 |
鞘内施用腺伴随病毒载体用于基因治疗
|
EP3371217A1
(en)
|
2015-11-08 |
2018-09-12 |
H. Hoffnabb-La Roche Ag |
Methods of screening for multispecific antibodies
|
WO2017083423A1
(en)
|
2015-11-10 |
2017-05-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for modulating aav infection
|
US20170151416A1
(en)
|
2015-12-01 |
2017-06-01 |
Invivo Therapeutics Corporation |
Methods and Systems for Delivery of a Trail of a Therapeutic Substance into an Anatomical Space
|
CN108603174A
(zh)
|
2015-12-01 |
2018-09-28 |
星火治疗有限公司 |
在适用于临床应用的无血清悬浮细胞培养体系中产生重组腺相关病毒(aav)载体的可扩展方法
|
WO2017096164A1
(en)
|
2015-12-02 |
2017-06-08 |
The Board Of Trustees Of The Leland Stanford Junior University |
Novel recombinant adeno-associated virus capsids with enhanced human skeletal muscle tropism
|
US10406244B2
(en)
|
2015-12-02 |
2019-09-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
AAV vectors with expanded packaging capacity
|
EP3383896A1
(en)
|
2015-12-03 |
2018-10-10 |
Genethon |
Compositions and methods for improving viral vector efficiency
|
EP3992283A1
(en)
|
2015-12-11 |
2022-05-04 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aavrh10
|
WO2017100674A1
(en)
|
2015-12-11 |
2017-06-15 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aav1
|
WO2017160360A2
(en)
|
2015-12-11 |
2017-09-21 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aav9
|
RU2727672C2
(ru)
|
2015-12-11 |
2020-07-22 |
Калифорния Инститьют Оф Текнолоджи |
Нацеливающие пептиды для направленной доставки аденоассоциированных вирусов (aav)
|
EP4215605A1
(en)
|
2015-12-11 |
2023-07-26 |
The Trustees of The University of Pennsylvania |
Scalable purification method for aav8
|
CN116478254A
(zh)
|
2015-12-14 |
2023-07-25 |
北卡罗来纳大学教堂山分校 |
增强细小病毒载体递送的修饰衣壳蛋白
|
WO2017112948A1
(en)
|
2015-12-24 |
2017-06-29 |
University Of Florida Research Foundation, Inc. |
Improved aav production using suspension adapted cells
|
WO2017123934A1
(en)
|
2016-01-13 |
2017-07-20 |
Merial, Inc. |
Recombinant aav vectors expressing osteoprotective genes, including has2 and lubricin, useful in the treatment of osteoarthritis and related joint conditions in mammals
|
US20190022251A1
(en)
|
2016-01-15 |
2019-01-24 |
Jichi Medical University |
Adeno-Associated Virus Virions for Treatment of Epilepsy
|
EP3411059A4
(en)
|
2016-02-02 |
2019-10-16 |
University Of Massachusetts |
METHOD FOR INCREASING THE EFFECTIVENESS OF THE SYSTEMIC DELIVERY OF AVV GENES TO THE CENTRAL NERVOUS SYSTEM
|
DK3411484T3
(da)
|
2016-02-05 |
2023-11-20 |
Univ Emory |
Injektion af enkeltstrenget eller selvkomplementær adeno-associeret virus 9 i cerebrospinalvæsken
|
WO2017139381A1
(en)
|
2016-02-08 |
2017-08-17 |
University Of Iowa Research Foundation |
Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
|
WO2017143100A1
(en)
|
2016-02-16 |
2017-08-24 |
The Board Of Trustees Of The Leland Stanford Junior University |
Novel recombinant adeno-associated virus capsids resistant to pre-existing human neutralizing antibodies
|
WO2017147477A1
(en)
|
2016-02-26 |
2017-08-31 |
University Of Florida Research Foundation, Inc. |
Aav heparin mutants that display significantly improved eye and brain transduction
|
CA3016314A1
(en)
|
2016-03-02 |
2017-09-08 |
Julianne REIDERS |
Therapy for frontotemporal dementia
|
IL302398A
(en)
|
2016-03-03 |
2023-06-01 |
Univ Massachusetts |
End-capped linear double-stranded DNA for non-viral gene transfer
|
MX2018010842A
(es)
|
2016-03-07 |
2019-07-04 |
Univ Iowa Res Found |
Expresion mediada por el virus adeno-asociado (aav) usando un promotor y pontenciador sintetico.
|
WO2017165167A1
(en)
|
2016-03-23 |
2017-09-28 |
The Regents Of The University Of California |
Methods of treating mitochondrial disorders
|
WO2017165859A1
(en)
|
2016-03-24 |
2017-09-28 |
Research Institute At Nationwide Children's Hospital |
Modified viral capsid proteins
|
CA3039910A1
(en)
|
2016-03-28 |
2017-10-05 |
The Regents Of The University Of California |
Anti-ryk antibodies and methods of using the same
|
KR102389674B1
(ko)
|
2016-03-28 |
2022-04-21 |
울트라제닉스 파마수티컬 인코포레이티드 |
아데노바이러스의 열 불활성화 방법
|
EP3436576A4
(en)
|
2016-03-30 |
2019-10-30 |
Spark Therapeutics, Inc. |
CELL LINE FOR THE PRODUCTION OF RECOMBINANT PROTEIN AND / OR A RECOMBINANT VIRAL VECTOR
|
WO2017173283A1
(en)
|
2016-03-31 |
2017-10-05 |
Spark Therapeutics, Inc. |
Column-based fully scalable raav manufacturing process
|
SG10202009852PA
(en)
|
2016-04-15 |
2020-11-27 |
Univ Pennsylvania |
Novel aav8 mutant capsids and compositions containing same
|
MX2018012663A
(es)
|
2016-04-16 |
2019-07-08 |
Univ Florida |
Metodos para aumentar la capacidad de actividad biológica del virus adenoasociado recombinante producido mediante el sistema baculovirus.
|
KR20180134846A
(ko)
|
2016-04-21 |
2018-12-19 |
바이로베크 인코포레이티드 |
곤충 세포에서의 aav 생산, 및 이를 위한 방법 및 조성물
|
EP3235516B1
(en)
|
2016-04-22 |
2019-06-26 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin |
Regulatable adeno-associated virus (aav) vector
|
EP3449250B1
(en)
|
2016-04-28 |
2020-11-04 |
Indiana University Research & Technology Corporation |
Methods and compositions for resolving components of a virus preparation
|
AU2017261249B2
(en)
|
2016-05-03 |
2021-05-06 |
Children's Medical Research Institute |
Adeno-associated virus polynucleotides, polypeptides and virions
|
WO2017192750A1
(en)
|
2016-05-04 |
2017-11-09 |
Oregon Health & Science University |
Recombinant adeno-associated viral vectors
|
MX2019012113A
(es)
|
2017-04-14 |
2020-09-10 |
Univ Nat Taiwan |
Terapia génica para la deficiencia de la aadc.
|