BR112012014677A2 - inibidores do vírus da hepatite c - Google Patents

inibidores do vírus da hepatite c

Info

Publication number
BR112012014677A2
BR112012014677A2 BR112012014677A BR112012014677A BR112012014677A2 BR 112012014677 A2 BR112012014677 A2 BR 112012014677A2 BR 112012014677 A BR112012014677 A BR 112012014677A BR 112012014677 A BR112012014677 A BR 112012014677A BR 112012014677 A2 BR112012014677 A2 BR 112012014677A2
Authority
BR
Brazil
Prior art keywords
hepatitis
virus inhibitors
compounds
virus
treatment
Prior art date
Application number
BR112012014677A
Other languages
English (en)
Inventor
bao-ning Su
Denis R St Laurent
Gan Wang
Jeffrey Lee Romine
John A Bender
John A Easter
Makonen Belema
Michael J Smith
Nicholas A Meanwell
Ningning Xu
Omar D Lopez
Piyasena Hewawasam
Qi Cheng
N Van Nguyen
Zhong Yang
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43479603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012014677(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of BR112012014677A2 publication Critical patent/BR112012014677A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

inibidores do vírus da hepatite c . a presente invenção refere-se aos compostos, composições e métodos para o tratamento de infecção pelo vírus da hepatite c (hcv). são também descritas composições farmacêuticas contendo tais compostos e métodos para usar estes compostos no tratamento de infecção por hcv.
BR112012014677A 2009-12-16 2010-12-13 inibidores do vírus da hepatite c BR112012014677A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28694209P 2009-12-16 2009-12-16
US12/957,512 US8377980B2 (en) 2009-12-16 2010-12-01 Hepatitis C virus inhibitors
PCT/US2010/060077 WO2011075439A1 (en) 2009-12-16 2010-12-13 Hepatitis c virus inhibitors

Publications (1)

Publication Number Publication Date
BR112012014677A2 true BR112012014677A2 (pt) 2015-09-15

Family

ID=43479603

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012014677A BR112012014677A2 (pt) 2009-12-16 2010-12-13 inibidores do vírus da hepatite c

Country Status (20)

Country Link
US (1) US8377980B2 (pt)
EP (1) EP2513091B1 (pt)
JP (1) JP5785189B2 (pt)
KR (1) KR20120107991A (pt)
CN (1) CN102741242B (pt)
AR (1) AR079634A1 (pt)
AU (1) AU2010332034B2 (pt)
BR (1) BR112012014677A2 (pt)
CA (1) CA2784662A1 (pt)
CL (1) CL2012001637A1 (pt)
CO (1) CO6561788A2 (pt)
EA (1) EA020815B1 (pt)
MA (1) MA33806B1 (pt)
MX (1) MX2012006635A (pt)
NZ (1) NZ601220A (pt)
PE (1) PE20121479A1 (pt)
SG (1) SG181700A1 (pt)
TN (1) TN2012000264A1 (pt)
TW (1) TWI487702B (pt)
WO (1) WO2011075439A1 (pt)

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MA33806B1 (fr) 2012-12-03
US8377980B2 (en) 2013-02-19
NZ601220A (en) 2014-07-25
EP2513091B1 (en) 2017-04-12
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TW201130825A (en) 2011-09-16
AU2010332034A1 (en) 2012-08-02
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WO2011075439A1 (en) 2011-06-23
JP5785189B2 (ja) 2015-09-24
AR079634A1 (es) 2012-02-08
KR20120107991A (ko) 2012-10-04
MX2012006635A (es) 2012-06-21
CN102741242B (zh) 2015-07-01
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CA2784662A1 (en) 2011-06-23
AU2010332034B2 (en) 2016-04-14
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