MX2020013416A - Compuestos de coumarina sustituidos con amina terciaria y sus usos como etiquetas fluorescentes. - Google Patents
Compuestos de coumarina sustituidos con amina terciaria y sus usos como etiquetas fluorescentes.Info
- Publication number
- MX2020013416A MX2020013416A MX2020013416A MX2020013416A MX2020013416A MX 2020013416 A MX2020013416 A MX 2020013416A MX 2020013416 A MX2020013416 A MX 2020013416A MX 2020013416 A MX2020013416 A MX 2020013416A MX 2020013416 A MX2020013416 A MX 2020013416A
- Authority
- MX
- Mexico
- Prior art keywords
- fluorescent labels
- tertiary amine
- amine substituted
- substituted coumarin
- coumarin compounds
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B57/00—Other synthetic dyes of known constitution
- C09B57/02—Coumarine dyes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Plural Heterocyclic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
Abstract
La presente solicitud se refiere a derivados de cumarina sustituidos con amina terciaria y sus usos como etiquetas fluorescentes. Estos compuestos se pueden usar como etiquetas fluorescentes para nucleótidos en aplicaciones de secuenciación de ácido nucleico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962812732P | 2019-03-01 | 2019-03-01 | |
PCT/EP2020/055257 WO2020178165A1 (en) | 2019-03-01 | 2020-02-28 | Tertiary amine substituted coumarin compounds and their uses as fluorescent labels |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020013416A true MX2020013416A (es) | 2021-04-28 |
Family
ID=69723946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020013416A MX2020013416A (es) | 2019-03-01 | 2020-02-28 | Compuestos de coumarina sustituidos con amina terciaria y sus usos como etiquetas fluorescentes. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20200277670A1 (es) |
EP (1) | EP3931190A1 (es) |
JP (1) | JP2022521866A (es) |
KR (1) | KR20210134210A (es) |
CN (1) | CN112654614A (es) |
AU (1) | AU2020233166A1 (es) |
BR (1) | BR112020026669A2 (es) |
CA (1) | CA3103636A1 (es) |
IL (1) | IL279660A (es) |
MX (1) | MX2020013416A (es) |
SG (1) | SG11202012554QA (es) |
WO (1) | WO2020178165A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20220107231A (ko) | 2019-11-27 | 2022-08-02 | 일루미나 케임브리지 리미티드 | 사이클로옥타테트라엔 함유 염료 및 조성물 |
US20220195516A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Methods, systems and compositions for nucleic acid sequencing |
US20220195518A1 (en) | 2020-12-22 | 2022-06-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing |
KR20240009435A (ko) | 2021-05-20 | 2024-01-22 | 일루미나, 인코포레이티드 | 합성에 의한 시퀀싱을 위한 조성물 및 방법 |
US20220403450A1 (en) | 2021-06-03 | 2022-12-22 | Illumina Software, Inc. | Systems and methods for sequencing nucleotides using two optical channels |
CN117580961A (zh) | 2021-09-01 | 2024-02-20 | Illumina公司 | 用于加速碱基判读的幅度调制 |
US20230183799A1 (en) | 2021-12-10 | 2023-06-15 | Illumina, Inc. | Parallel sample and index sequencing |
WO2023175041A1 (en) | 2022-03-15 | 2023-09-21 | Illumina, Inc. | Concurrent sequencing of forward and reverse complement strands on concatenated polynucleotides |
WO2023186815A1 (en) | 2022-03-28 | 2023-10-05 | Illumina Cambridge Limited | Labeled avidin and methods for sequencing |
US20230313292A1 (en) | 2022-03-29 | 2023-10-05 | Illumina Cambridge Limited | Chromenoquinoline dyes and uses in sequencing |
AU2023246851A1 (en) | 2022-03-31 | 2024-01-18 | Illumina, Inc. | Compositions and methods for improving sequencing signals |
CA3222797A1 (en) | 2022-03-31 | 2023-10-05 | Ramesh NEELAKANDAN | Nucleosides and nucleotides with 3' vinyl blocking group |
US20230383342A1 (en) | 2022-05-31 | 2023-11-30 | Illumina Cambridge Limited | Compositions and methods for nucleic acid sequencing |
US20230416279A1 (en) | 2022-06-28 | 2023-12-28 | Illumina Cambridge Limited | Fluorescent dyes containing fused tetracyclic bis-boron heterocycle and uses in sequencing |
US20240140939A1 (en) | 2022-09-30 | 2024-05-02 | Illumina Cambridge Limited | Compositions and methods for reducing photo damage during sequencing |
Family Cites Families (40)
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CH390250A (de) * | 1958-06-19 | 1965-07-30 | Geigy Ag J R | Verfahren zur Herstellung von fluoreszierenden Farbstoffen |
US5268486A (en) | 1986-04-18 | 1993-12-07 | Carnegie-Mellon Unversity | Method for labeling and detecting materials employing arylsulfonate cyanine dyes |
US5302509A (en) | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
US5459276A (en) * | 1994-05-20 | 1995-10-17 | Molecular Probes, Inc. | Benzazolylcoumarin-based ion indicators for heavy metals |
US5501980A (en) * | 1994-05-20 | 1996-03-26 | Molecular Probes, Inc. | Benzazolylcoumarin-based ion indicators |
JP2999841B2 (ja) * | 1991-04-03 | 2000-01-17 | 三井化学株式会社 | 発光スクリーン用樹脂組成物 |
ATE147400T1 (de) * | 1991-08-13 | 1997-01-15 | Bayer Ag | Fluoreszierendes etikett |
DE4302459A1 (de) * | 1993-01-29 | 1994-08-04 | Bayer Ag | Sulfocumarinhaltige Nukleotide und deren Verwendung in Nachweisverfahren für Nukleinsäuren |
JPH0743896A (ja) * | 1993-07-28 | 1995-02-14 | Toyobo Co Ltd | 光重合性組成物 |
US5846719A (en) | 1994-10-13 | 1998-12-08 | Lynx Therapeutics, Inc. | Oligonucleotide tags for sorting and identification |
DE69837913T2 (de) | 1997-04-01 | 2008-02-07 | Solexa Ltd., Saffron Walden | Verfahren zur vervielfältigung von nukleinsäure |
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JP2002521064A (ja) | 1998-07-30 | 2002-07-16 | ソレックサ リミテッド | アレイ生体分子およびシークエンシングにおけるその使用 |
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US10041937B2 (en) * | 2013-05-30 | 2018-08-07 | Canon Kabushiki Kaisha | Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent |
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CN108752327B (zh) * | 2018-04-17 | 2020-11-13 | 浙江工业大学 | 3-(2-苯并恶唑)香豆素酰胺化合物及其制备方法和应用 |
-
2020
- 2020-02-28 CA CA3103636A patent/CA3103636A1/en active Pending
- 2020-02-28 EP EP20707631.6A patent/EP3931190A1/en active Pending
- 2020-02-28 JP JP2020572442A patent/JP2022521866A/ja active Pending
- 2020-02-28 CN CN202080003505.7A patent/CN112654614A/zh active Pending
- 2020-02-28 SG SG11202012554QA patent/SG11202012554QA/en unknown
- 2020-02-28 AU AU2020233166A patent/AU2020233166A1/en active Pending
- 2020-02-28 US US16/805,125 patent/US20200277670A1/en active Pending
- 2020-02-28 WO PCT/EP2020/055257 patent/WO2020178165A1/en active Application Filing
- 2020-02-28 KR KR1020207037219A patent/KR20210134210A/ko unknown
- 2020-02-28 BR BR112020026669-8A patent/BR112020026669A2/pt unknown
- 2020-02-28 MX MX2020013416A patent/MX2020013416A/es unknown
- 2020-12-21 IL IL279660A patent/IL279660A/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL279660A (en) | 2021-03-01 |
BR112020026669A2 (pt) | 2021-09-08 |
EP3931190A1 (en) | 2022-01-05 |
JP2022521866A (ja) | 2022-04-13 |
WO2020178165A1 (en) | 2020-09-10 |
KR20210134210A (ko) | 2021-11-09 |
AU2020233166A1 (en) | 2021-01-07 |
SG11202012554QA (en) | 2021-01-28 |
CN112654614A (zh) | 2021-04-13 |
CA3103636A1 (en) | 2020-09-10 |
US20200277670A1 (en) | 2020-09-03 |
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