EA200201262A1 - Композиции для лечения флавивирусных и пестивирусных инфекций и способы их применения - Google Patents

Композиции для лечения флавивирусных и пестивирусных инфекций и способы их применения

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Publication number
EA200201262A1
EA200201262A1 EA200201262A EA200201262A EA200201262A1 EA 200201262 A1 EA200201262 A1 EA 200201262A1 EA 200201262 A EA200201262 A EA 200201262A EA 200201262 A EA200201262 A EA 200201262A EA 200201262 A1 EA200201262 A1 EA 200201262A1
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EA
Eurasian Patent Office
Prior art keywords
flavivirus
compositions
treatment
methods
application
Prior art date
Application number
EA200201262A
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English (en)
Other versions
EA007867B1 (ru
Inventor
Жан-Пьер Соммадосси
Паоло Лаколла
Original Assignee
Айденикс (Кайман) Лимитед
Университа Дельи Студи Ди Кальяри
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26902464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200201262(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Айденикс (Кайман) Лимитед, Университа Дельи Студи Ди Кальяри filed Critical Айденикс (Кайман) Лимитед
Publication of EA200201262A1 publication Critical patent/EA200201262A1/ru
Publication of EA007867B1 publication Critical patent/EA007867B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/00—Medicinal preparations containing peptides
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
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    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
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    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
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    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
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    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Abstract

Настоящее изобретение относится к композиции и способу для лечения хозяина, инфицированного флавивирусом или пестивирусом, который включает введение эффективного для уничтожения флавивируса или пестивируса количества описанного 1'-, 2'- или 3'-модифицированного нуклеозида, его фармацевтически приемлемой соли или пролекарства.Отчет о международном поиске был опубликован 2002.05.02.
EA200201262A 2000-05-26 2001-05-23 Композиции для лечения флавивирусных и пестивирусных инфекций и способы их применения EA007867B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20767400P 2000-05-26 2000-05-26
US28327601P 2001-04-11 2001-04-11
PCT/US2001/016687 WO2001092282A2 (en) 2000-05-26 2001-05-23 Methods and compositions for treating flaviviruses and pestiviruses

Publications (2)

Publication Number Publication Date
EA200201262A1 true EA200201262A1 (ru) 2003-08-28
EA007867B1 EA007867B1 (ru) 2007-02-27

Family

ID=26902464

Family Applications (2)

Application Number Title Priority Date Filing Date
EA200601591A EA200601591A1 (ru) 2000-05-26 2001-05-23 Применение рибонуклеозидных соединений для лечения флавивирусных и пестивирусных инфекций
EA200201262A EA007867B1 (ru) 2000-05-26 2001-05-23 Композиции для лечения флавивирусных и пестивирусных инфекций и способы их применения

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA200601591A EA200601591A1 (ru) 2000-05-26 2001-05-23 Применение рибонуклеозидных соединений для лечения флавивирусных и пестивирусных инфекций

Country Status (24)

Country Link
US (9) US6812219B2 (ru)
EP (2) EP1736478B1 (ru)
JP (2) JP5230052B2 (ru)
KR (2) KR20030036189A (ru)
CN (2) CN101099745A (ru)
AP (2) AP1727A (ru)
AR (1) AR032883A1 (ru)
AU (2) AU2001272923A1 (ru)
BR (1) BR0111196A (ru)
CA (1) CA2410579C (ru)
CZ (1) CZ301182B6 (ru)
EA (2) EA200601591A1 (ru)
IL (1) IL153020A0 (ru)
MA (1) MA26916A1 (ru)
MX (1) MXPA02011691A (ru)
NO (1) NO327249B1 (ru)
NZ (2) NZ536570A (ru)
OA (1) OA12382A (ru)
PE (1) PE20020051A1 (ru)
PL (1) PL359169A1 (ru)
TW (1) TW200425898A (ru)
WO (1) WO2001092282A2 (ru)
YU (1) YU92202A (ru)
ZA (2) ZA200210112B (ru)

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AR032883A1 (es) 2003-12-03
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US20060166865A1 (en) 2006-07-27
AU2007202602A1 (en) 2007-07-19
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