AU2001255495A1 - Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rnain patients having chronic hepatitis c infection - Google Patents
Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rnain patients having chronic hepatitis c infectionInfo
- Publication number
- AU2001255495A1 AU2001255495A1 AU2001255495A AU5549501A AU2001255495A1 AU 2001255495 A1 AU2001255495 A1 AU 2001255495A1 AU 2001255495 A AU2001255495 A AU 2001255495A AU 5549501 A AU5549501 A AU 5549501A AU 2001255495 A1 AU2001255495 A1 AU 2001255495A1
- Authority
- AU
- Australia
- Prior art keywords
- rnain
- ribavirin
- infection
- patients
- combination therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19880100P | 2000-04-20 | 2000-04-20 | |
US60198801 | 2000-04-20 | ||
PCT/US2001/012760 WO2001081359A1 (en) | 2000-04-20 | 2001-04-18 | Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rna in patients having chronic hepatitis c infection |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001255495A1 true AU2001255495A1 (en) | 2001-11-07 |
Family
ID=22734903
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001255495A Abandoned AU2001255495A1 (en) | 2000-04-20 | 2001-04-18 | Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rnain patients having chronic hepatitis c infection |
Country Status (5)
Country | Link |
---|---|
US (2) | US6924270B2 (en) |
EP (1) | EP1282632A1 (en) |
AR (1) | AR031572A1 (en) |
AU (1) | AU2001255495A1 (en) |
WO (1) | WO2001081359A1 (en) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001255495A1 (en) | 2000-04-20 | 2001-11-07 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rnain patients having chronic hepatitis c infection |
MY164523A (en) * | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
US6812219B2 (en) | 2000-05-26 | 2004-11-02 | Idenix Pharmaceuticals, Inc. | Methods and compositions for treating flaviviruses and pestiviruses |
US20060024270A1 (en) * | 2000-08-23 | 2006-02-02 | The New York Hospital Medical Center Of Queens | Compositions and methods for preventing or treating encephalitis with interferon |
CN1516599A (en) * | 2000-10-18 | 2004-07-28 | ���鹫˾ | Method for joint treatment of chronic hepatitis C infection using ribavirin-polyvinyl glycol interferon alpha |
US7608600B2 (en) | 2002-06-28 | 2009-10-27 | Idenix Pharmaceuticals, Inc. | Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections |
KR20050048544A (en) | 2002-06-28 | 2005-05-24 | 이데닉스 (케이만) 리미티드 | Modified 2' and 3'-nucleoside prodrugs for treating flaviviridae infections |
MXPA04012802A (en) * | 2002-06-28 | 2005-04-19 | Idenix Cayman Ltd | 2aCOE-C-METHYL-3aCOE-O-L-VALINE ESTER RIBOFURANOSYL CYTIDINE FOR TREATMENT OF FLAVIVIRIDAE INFECTIONS. |
CN101172993A (en) * | 2002-06-28 | 2008-05-07 | 埃迪尼克斯(开曼)有限公司 | 2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections |
US8476254B2 (en) | 2002-07-02 | 2013-07-02 | Corcept Therapeutics, Inc. | Methods for treating psychosis associated with interferson-α therapy |
RU2005118421A (en) * | 2002-11-15 | 2006-01-20 | Айденикс (Кайман) Лимитед (Ky) | 2'-BRANCHED NUCLEOSIDES AND MUTATION FLAVIVIRIDAE |
RU2005121904A (en) * | 2002-12-12 | 2006-01-20 | Айденикс (Кайман) Лимитед (Ky) | METHOD FOR PRODUCING 2`-BRANCHED NUCLEOSIDES |
US20040181051A1 (en) * | 2002-12-23 | 2004-09-16 | Richard Storer | Process for the production of 3'-nucleoside prodrugs |
ES2726998T3 (en) | 2003-05-30 | 2019-10-11 | Gilead Pharmasset Llc | Modified fluorinated nucleoside analogs |
EP1668031B1 (en) | 2003-08-07 | 2008-03-12 | ZymoGenetics, Inc. | Homogeneous preparations of il-29 |
ZA200601181B (en) * | 2003-08-13 | 2007-04-25 | Smith Howard J & Ass Pty Ltd | Method of treating viral infections |
CA2537849A1 (en) * | 2003-09-11 | 2005-03-17 | F. Hoffmann-La Roche Ag | Process for preparing antiviral nucleoside derivatives |
US20050244423A1 (en) * | 2004-04-02 | 2005-11-03 | Klucher Kevin M | Methods for treating viral infection using IL-28 and IL-29 cysteine mutants |
BRPI0512360A (en) * | 2004-06-23 | 2008-03-11 | Idenix Cayman Ltd | 5-aza-7-deazapurine derivatives for the treatment of flaviviridae |
EP3109244B1 (en) | 2004-09-14 | 2019-03-06 | Gilead Pharmasset LLC | Preparation of 2'fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives |
CN101048172A (en) * | 2004-10-29 | 2007-10-03 | 英特塞尔股份公司 | Hcv vaccines for chronic hcv patients |
JP5409008B2 (en) | 2005-11-11 | 2014-02-05 | バーテックス ファーマシューティカルズ インコーポレイテッド | Hepatitis C virus variant |
US7705138B2 (en) * | 2005-11-11 | 2010-04-27 | Vertex Pharmaceuticals Incorporated | Hepatitis C virus variants |
ES2422290T3 (en) * | 2005-12-23 | 2013-09-10 | Idenix Pharmaceuticals Inc | Procedure for preparing a synthetic intermediate for the preparation of branched nucleosides |
US7964580B2 (en) | 2007-03-30 | 2011-06-21 | Pharmasset, Inc. | Nucleoside phosphoramidate prodrugs |
NZ593648A (en) | 2008-12-23 | 2013-09-27 | Gilead Pharmasset Llc | Nucleoside phosphoramidates |
TW201031675A (en) | 2008-12-23 | 2010-09-01 | Pharmasset Inc | Synthesis of purine nucleosides |
CN102753563A (en) | 2008-12-23 | 2012-10-24 | 吉利德制药有限责任公司 | Nucleoside analogs |
US8618076B2 (en) | 2009-05-20 | 2013-12-31 | Gilead Pharmasset Llc | Nucleoside phosphoramidates |
TWI576352B (en) | 2009-05-20 | 2017-04-01 | 基利法瑪席特有限責任公司 | Nucleoside phosphoramidates |
CN102858790A (en) | 2010-03-31 | 2013-01-02 | 吉利德制药有限责任公司 | Nucleoside Phosphoramidates |
AU2011268498A1 (en) | 2010-06-24 | 2013-01-31 | Genoscience Pharma Sas | Treatment of hepatitis C virus related diseases using hydroxychloroquine or a combination of hydroxychloroquine and an anti-viral agent |
JP2013542206A (en) | 2010-10-05 | 2013-11-21 | ノバルティス アーゲー | New treatment of hepatitis C virus infection |
AU2011336632B2 (en) | 2010-11-30 | 2015-09-03 | Gilead Pharmasset Llc | Compounds |
EP2646038A1 (en) * | 2010-11-30 | 2013-10-09 | Novartis AG | New treatments of hepatitis c virus infection |
CN103476409A (en) | 2011-03-31 | 2013-12-25 | 诺华股份有限公司 | Alisporivir to treat hepatitis C virus infection |
CN103648516A (en) | 2011-04-13 | 2014-03-19 | 诺华股份有限公司 | Treatment of hepatitis c virus infection with alisporivir |
WO2012176149A1 (en) | 2011-06-23 | 2012-12-27 | Panmed Ltd. | Treatment of hepatitis c virus |
EP2709613B2 (en) | 2011-09-16 | 2020-08-12 | Gilead Pharmasset LLC | Methods for treating hcv |
AU2012314517A1 (en) * | 2011-09-27 | 2014-04-17 | Novartis Ag | Alisporivr for treatment of Hepatis C virus infection |
US8889159B2 (en) | 2011-11-29 | 2014-11-18 | Gilead Pharmasset Llc | Compositions and methods for treating hepatitis C virus |
WO2014120981A1 (en) | 2013-01-31 | 2014-08-07 | Gilead Pharmasset Llc | Combination formulation of two antiviral compounds |
WO2014122537A2 (en) | 2013-02-05 | 2014-08-14 | Genoscience Sa | Pharmaceutical compositions and methods of treating hepatitis c virus infection using a combination of hydroxychloroquine and ribavirin |
NZ716840A (en) | 2013-08-27 | 2017-06-30 | Gilead Pharmasset Llc | Combination formulation of two antiviral compounds |
CN111320662B (en) * | 2020-02-17 | 2022-11-25 | 南京医科大学 | N-benzyl substituted diamidinonazine derivative and pharmaceutical application thereof |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4211771A (en) * | 1971-06-01 | 1980-07-08 | Robins Ronald K | Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide |
US3984396A (en) * | 1971-06-01 | 1976-10-05 | Icn Pharmaceuticals, Inc. | 1-(β,-D-ribofuranosyl)-1,2,4-triazole acid esters |
GB1482736A (en) | 1974-03-18 | 1977-08-10 | Icn Pharmaceuticals | 1-(beta-d-ribofuranosyl)-1,2,4-triazole acid derivatives |
US4544741A (en) | 1982-03-29 | 1985-10-01 | Robins Roland K | Azole dinucleotide compounds and methods for their production |
US5674911A (en) | 1987-02-20 | 1997-10-07 | Cytrx Corporation | Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use |
US4925930A (en) | 1988-11-02 | 1990-05-15 | Nucleic Acid Research Institute | Synthesis and anti-leukemic activity of alkyl-1-(β-D-ribofuranosyl)[1,2,4]triazole-3-carboximidates |
EP0625991B1 (en) * | 1992-02-10 | 1999-04-28 | Interferon Sciences, Inc. | Improved alpha interferon composition and method for its production from human peripheral blood leukocytes |
GB9307043D0 (en) * | 1993-04-05 | 1993-05-26 | Norsk Hydro As | Chemical compounds |
US5681811A (en) | 1993-05-10 | 1997-10-28 | Protein Delivery, Inc. | Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same |
US6387365B1 (en) * | 1995-05-19 | 2002-05-14 | Schering Corporation | Combination therapy for chronic hepatitis C infection |
US5981507A (en) | 1995-12-14 | 1999-11-09 | Advanced Magnetics, Inc. | Polymeric carriers linked to nucleotide analogues via a phosphoramide bond |
TW517067B (en) | 1996-05-31 | 2003-01-11 | Hoffmann La Roche | Interferon conjugates |
WO1998021223A1 (en) | 1996-11-12 | 1998-05-22 | Medivir Ab | Nucleosides |
US6403564B1 (en) * | 1998-10-16 | 2002-06-11 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection |
RU2001113268A (en) * | 1998-10-16 | 2003-09-27 | Шеринг Корпорейшн (US) | Combined therapy with ribavirin and interferon α to remove hepatitis C virus detected RNA in patients with chronic hepatitis C |
US6277830B1 (en) * | 1998-10-16 | 2001-08-21 | Schering Corporation | 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon |
AU2001255495A1 (en) | 2000-04-20 | 2001-11-07 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rnain patients having chronic hepatitis c infection |
US6673775B2 (en) | 2001-04-18 | 2004-01-06 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection |
-
2001
- 2001-04-18 AU AU2001255495A patent/AU2001255495A1/en not_active Abandoned
- 2001-04-18 US US09/837,491 patent/US6924270B2/en not_active Expired - Fee Related
- 2001-04-18 EP EP01928662A patent/EP1282632A1/en not_active Withdrawn
- 2001-04-18 WO PCT/US2001/012760 patent/WO2001081359A1/en active Application Filing
- 2001-04-19 AR ARP010101840A patent/AR031572A1/en unknown
-
2004
- 2004-07-06 US US10/885,374 patent/US7115578B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AR031572A1 (en) | 2003-09-24 |
US6924270B2 (en) | 2005-08-02 |
US20020055473A1 (en) | 2002-05-09 |
US7115578B2 (en) | 2006-10-03 |
EP1282632A1 (en) | 2003-02-12 |
US20050004053A1 (en) | 2005-01-06 |
WO2001081359A1 (en) | 2001-11-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2001255495A1 (en) | Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rnain patients having chronic hepatitis c infection | |
AU1197600A (en) | Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rnain patients having chronic hepatitis c infection | |
ZA988466B (en) | Combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection | |
HK1016505A1 (en) | Combination therapy for eradicating detectable hcv-rna in patients having chronic hepatitis c infection | |
DE60212048D1 (en) | Catheter with improved distal pushing ability | |
AU4806600A (en) | Medical suction valve | |
IL196301A0 (en) | Medicament for the treatment of hapatitis c | |
AU2002321888A1 (en) | Medical needle | |
AU2001265173A1 (en) | Flexible endodontic syringe | |
AU2001234425A1 (en) | Multi-lumen medical device | |
AU2002220268A1 (en) | Anti-drawback medical valve | |
AU2001241963A1 (en) | Improved medical procedure | |
AUPQ893200A0 (en) | Medical residue treatment | |
AU2002254724A1 (en) | Dual-profile steerable catheter | |
AU2002222853A1 (en) | Therapeutic compounds | |
AU2002230684A1 (en) | Dual element sensor medical electrode | |
AU2002303502A1 (en) | Improved leads for the treatment of patients with chf | |
AU2002355230A1 (en) | Blood dialyzer | |
HUP0200447A2 (en) | Ribavirin-interferon alfa combination theory for eradicating detectable hcv-rna in patients having chronic hepatitis c infection | |
AU2001243299A1 (en) | Luminescent medical bandage | |
AU2001243515A1 (en) | Combination drug therapy | |
AU2002322082A1 (en) | Pharmaceutical composition for the treatment of viral infection | |
MXPA03006412A (en) | Methods of administering epothilone analogs for the treatment of cancer. | |
AU2001232053A1 (en) | System for the extracorporeal treatment of blood | |
AU2002213420A1 (en) | Single-use syringe |