EA200201263A1 - СПОСОБЫ ЛЕЧЕНИЯ ИНФЕКЦИЙ, ВЫЗЫВАЕМЫХ ВИРУСОМ ГЕПАТИТА ДЕЛЬТА, С ИСПОЛЬЗОВАНИЕМ β-L-2'-ДЕЗОКСИНУКЛЕОЗИДОВ - Google Patents

СПОСОБЫ ЛЕЧЕНИЯ ИНФЕКЦИЙ, ВЫЗЫВАЕМЫХ ВИРУСОМ ГЕПАТИТА ДЕЛЬТА, С ИСПОЛЬЗОВАНИЕМ β-L-2'-ДЕЗОКСИНУКЛЕОЗИДОВ

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Publication number
EA200201263A1
EA200201263A1 EA200201263A EA200201263A EA200201263A1 EA 200201263 A1 EA200201263 A1 EA 200201263A1 EA 200201263 A EA200201263 A EA 200201263A EA 200201263 A EA200201263 A EA 200201263A EA 200201263 A1 EA200201263 A1 EA 200201263A1
Authority
EA
Eurasian Patent Office
Prior art keywords
deoxynucleosides
caused
methods
hepatitis delta
treating infections
Prior art date
Application number
EA200201263A
Other languages
English (en)
Other versions
EA005890B1 (ru
Inventor
Жан-Пьер Соммадосси
Мартин Л. Брайант
Original Assignee
Айденикс (Кайман) Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Айденикс (Кайман) Лимитед filed Critical Айденикс (Кайман) Лимитед
Publication of EA200201263A1 publication Critical patent/EA200201263A1/ru
Publication of EA005890B1 publication Critical patent/EA005890B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Abstract

Способ и композиция для лечения хозяина, инфицированного вирусом гепатита D, где указанный способ предусматривает введение эффективного для лечения гепатита D количества описанного 2'-дезокси-β-L-эритропентофуранонуклеозида или его фармацевтически приемлемой соли или пролекарства.Отчет о международном поиске был опубликован 2002.05.30.
EA200201263A 2000-05-26 2001-05-29 СПОСОБЫ ЛЕЧЕНИЯ ИНФЕКЦИЙ, ВЫЗЫВАЕМЫХ ВИРУСОМ ГЕПАТИТА ДЕЛЬТА, С ИСПОЛЬЗОВАНИЕМ β-L-2'-ДЕЗОКСИНУКЛЕОЗИДОВ EA005890B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20753800P 2000-05-26 2000-05-26
PCT/US2001/017301 WO2001091737A2 (en) 2000-05-26 2001-05-29 Methods for treating hepatitis delta virus infection with beta-l-2' deoxy-nucleosides

Publications (2)

Publication Number Publication Date
EA200201263A1 true EA200201263A1 (ru) 2003-06-26
EA005890B1 EA005890B1 (ru) 2005-06-30

Family

ID=22771005

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200201263A EA005890B1 (ru) 2000-05-26 2001-05-29 СПОСОБЫ ЛЕЧЕНИЯ ИНФЕКЦИЙ, ВЫЗЫВАЕМЫХ ВИРУСОМ ГЕПАТИТА ДЕЛЬТА, С ИСПОЛЬЗОВАНИЕМ β-L-2'-ДЕЗОКСИНУКЛЕОЗИДОВ

Country Status (18)

Country Link
US (1) US6596700B2 (ru)
EP (1) EP1292313B1 (ru)
JP (1) JP2004513070A (ru)
KR (1) KR100854398B1 (ru)
CN (1) CN100490818C (ru)
AT (1) ATE275406T1 (ru)
AU (3) AU2001263484B2 (ru)
BR (1) BR0111195A (ru)
CA (1) CA2410488C (ru)
DE (1) DE60105424T2 (ru)
EA (1) EA005890B1 (ru)
ES (1) ES2227203T3 (ru)
HK (1) HK1050999A1 (ru)
IL (1) IL153078A0 (ru)
MX (1) MXPA02011641A (ru)
TR (1) TR200402565T4 (ru)
WO (1) WO2001091737A2 (ru)
ZA (2) ZA200210100B (ru)

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WO2019009759A1 (ru) * 2017-07-03 2019-01-10 Александр Васильевич ИВАЩЕНКО Комбинированный лекарственный препарат для терапии вирусных инфекций
WO2019031981A1 (ru) * 2017-08-11 2019-02-14 Александр Васильевич ИВАЩЕНКО Ингибитор входа вируса гепатита и фармацевтическая композиция для лечения гепатита
US10683315B2 (en) 2017-02-28 2020-06-16 Alexandre Vasilievich Ivachtchenko Prodrug of an HCV NS5B polymerase inhibitor and method of production and application thereof

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Publication number Priority date Publication date Assignee Title
US10683315B2 (en) 2017-02-28 2020-06-16 Alexandre Vasilievich Ivachtchenko Prodrug of an HCV NS5B polymerase inhibitor and method of production and application thereof
WO2019009759A1 (ru) * 2017-07-03 2019-01-10 Александр Васильевич ИВАЩЕНКО Комбинированный лекарственный препарат для терапии вирусных инфекций
WO2019031981A1 (ru) * 2017-08-11 2019-02-14 Александр Васильевич ИВАЩЕНКО Ингибитор входа вируса гепатита и фармацевтическая композиция для лечения гепатита

Also Published As

Publication number Publication date
CA2410488A1 (en) 2001-12-06
HK1050999A1 (en) 2003-07-18
ZA200210100B (en) 2004-06-22
AU6348401A (en) 2001-12-11
AU2001263484B2 (en) 2006-12-14
DE60105424T2 (de) 2005-09-22
EA005890B1 (ru) 2005-06-30
ES2227203T3 (es) 2005-04-01
DE60105424D1 (de) 2004-10-14
WO2001091737A2 (en) 2001-12-06
CA2410488C (en) 2009-10-27
CN100490818C (zh) 2009-05-27
ATE275406T1 (de) 2004-09-15
EP1292313A2 (en) 2003-03-19
TR200402565T4 (tr) 2004-12-21
US6596700B2 (en) 2003-07-22
KR20030031487A (ko) 2003-04-21
BR0111195A (pt) 2004-07-20
CN1444483A (zh) 2003-09-24
WO2001091737A3 (en) 2002-05-30
KR100854398B1 (ko) 2008-08-26
IL153078A0 (en) 2003-06-24
MXPA02011641A (es) 2004-07-30
JP2004513070A (ja) 2004-04-30
EP1292313B1 (en) 2004-09-08
US20020035085A1 (en) 2002-03-21
AU2006252214A1 (en) 2007-01-18
ZA200404304B (en) 2005-03-30

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