EA020671B1 - ПРОИЗВОДНЫЕ 1,2,4-ТРИАЗОЛО[4,3-a]ПИРИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПОЛОЖИТЕЛЬНЫХ АЛЛОСТЕРИЧЕСКИХ МОДУЛЯТОРОВ РЕЦЕПТОРОВ mGluR2 - Google Patents

ПРОИЗВОДНЫЕ 1,2,4-ТРИАЗОЛО[4,3-a]ПИРИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПОЛОЖИТЕЛЬНЫХ АЛЛОСТЕРИЧЕСКИХ МОДУЛЯТОРОВ РЕЦЕПТОРОВ mGluR2 Download PDF

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Publication number
EA020671B1
EA020671B1 EA201190301A EA201190301A EA020671B1 EA 020671 B1 EA020671 B1 EA 020671B1 EA 201190301 A EA201190301 A EA 201190301A EA 201190301 A EA201190301 A EA 201190301A EA 020671 B1 EA020671 B1 EA 020671B1
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Eurasian Patent Office
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formula
disorders
chloro
mmol
alkyl
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EA201190301A
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English (en)
Russian (ru)
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EA201190301A1 (ru
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Хосе Мария Сид-Нуньес
Ана Изабель Де Лукас Оливарес
Андрес Авелино Трабанко-Суарес
Грегор Джеймс Макдональд
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Янссен Фармасьютикалз, Инк.
Аддекс Фарма С.А.
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Publication of EA201190301A1 publication Critical patent/EA201190301A1/ru
Publication of EA020671B1 publication Critical patent/EA020671B1/ru

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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EA201190301A 2009-05-12 2010-05-11 ПРОИЗВОДНЫЕ 1,2,4-ТРИАЗОЛО[4,3-a]ПИРИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПОЛОЖИТЕЛЬНЫХ АЛЛОСТЕРИЧЕСКИХ МОДУЛЯТОРОВ РЕЦЕПТОРОВ mGluR2 EA020671B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09160067 2009-05-12
PCT/EP2010/002908 WO2010130422A1 (en) 2009-05-12 2010-05-11 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors

Publications (2)

Publication Number Publication Date
EA201190301A1 EA201190301A1 (ru) 2012-06-29
EA020671B1 true EA020671B1 (ru) 2014-12-30

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EA201190301A EA020671B1 (ru) 2009-05-12 2010-05-11 ПРОИЗВОДНЫЕ 1,2,4-ТРИАЗОЛО[4,3-a]ПИРИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПОЛОЖИТЕЛЬНЫХ АЛЛОСТЕРИЧЕСКИХ МОДУЛЯТОРОВ РЕЦЕПТОРОВ mGluR2

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US (1) US8946205B2 (enExample)
EP (1) EP2430031B1 (enExample)
JP (1) JP5707390B2 (enExample)
KR (1) KR20120035158A (enExample)
CN (1) CN102439015B (enExample)
AR (1) AR076859A1 (enExample)
AU (1) AU2010246607B2 (enExample)
BR (1) BRPI1010831A2 (enExample)
CA (1) CA2760259C (enExample)
CL (1) CL2011002837A1 (enExample)
EA (1) EA020671B1 (enExample)
ES (1) ES2409006T3 (enExample)
IL (1) IL215910A (enExample)
MX (1) MX2011011962A (enExample)
MY (1) MY153912A (enExample)
NZ (1) NZ596053A (enExample)
SG (1) SG176018A1 (enExample)
TW (1) TW201100417A (enExample)
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US8765767B2 (en) 2012-03-16 2014-07-01 Bristol-Myers Squibb Company Positive allosteric modulators of mGluR2
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
WO2015042243A1 (en) 2013-09-19 2015-03-26 Bristol-Myers Squibb Company Triazolopyridine ether derivatives and their use in neurological and pyschiatric disorders
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EA202192105A3 (ru) 2014-02-04 2022-02-28 Янссен Фармацевтика Нв Комбинации, содержащие положительные аллостерические модуляторы или ортостерические агонисты метаботропного глутаматергического рецептора 2 подтипа, и их применение
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JP2012526735A (ja) 2012-11-01
AR076859A1 (es) 2011-07-13
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