CN110869072A - 用于穿戴式注射器的模块化驱动机构 - Google Patents
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Abstract
模块化驱动机构选择性地可固定在穿戴式注射器内。所述驱动系统包括箱架和安装在所述箱架内的伸缩式驱动组件。所述驱动组件包括相对于所述箱架可旋转的第一轴以及与所述第一轴连接并且相对第一轴轴向可移动的第二轴。所述第一轴的旋转轴向驱动第二轴。所述箱架包括轴承和从所述箱架的后端向前轴向突出到所述箱架中的弹性可扩展的轴环之一，且所述第一轴包括所述轴承和从所述第一轴的后端向后轴向突出的所述弹性可扩展的轴环中的另一个。所述轴环被配置为弹性地卡接到所述轴承的过盈元件上，通过所述轴环与所述轴承的啮合轴向地将所述第一轴固定到所述箱架并且允许所述第一轴绕所述轴承旋转。
Description
相关申请的交叉引用
该申请要求2017年5月30日提交的第62/512505号、标题为“模块化驱动装置-允许TSA反向的轴承卡件”的美国临时专利申请的优先权，其全部内容通过引用包含于此。
技术领域
本公开总地针对模块化驱动机构，更具体地说，针对在穿戴式注射器中可固定的模块化驱动机构。
背景技术
穿戴式注射器是一种复杂的医疗设备，包括组装在其中的许多相互连接的操作部件。典型地，例如，注射器驱动系统包括多个操作上相互连接的复杂零件组成，用于通过注射针或插管将物质从注射器内的储存器驱动和注射到用户。众所周知，操作部件及其组装成本、以及为了尽量减少不合格设备的制造和交付而采用的质量控制程序的成本，构成了消费者购买医疗设备的成本。
因此，希望使元件成本最小化并最大限度地简化设备组装。从多个可拆卸模块构造该设备能够有助于简化组装(通过在组装设备之前组装各个模块)，同时也简化了替换有缺陷的部件/模块(作为质量控制的一部分)。此外，用聚合物部件构造模块能够进一步降低成本。
因此，制造可固定到注射器的模块化驱动机构组件是有利的，该模块化驱动机构组件可至少部分地包括聚合物部件。
发明内容
简而言之，本公开的一方面涉及一种用于容置有药筒的穿戴式注射器的模块化驱动机构，其中所述药筒在一端由活塞密封。所述驱动机构包括在所述注射器内选择性地可固定的箱架以及安装在所述箱架内的伸缩式驱动组件。所述伸缩式驱动组件包括相对于所述箱架可旋转的第一轴，以及与所述第一轴伸缩式连接并且相对于所述第一轴轴向可移动的第二轴。所述第一轴的旋转将所述第二轴从缩回组态轴向驱动到延伸组态，从而在所述药筒内啮合并推进所述活塞。所述第二轴相对于所述箱架可旋转地固定。所述箱架包括轴承和从所述箱架的后端向前轴向突出到所述箱架中的弹性可扩展的轴环之一，且所述第一轴包括所述轴承和从所述第一轴的后端向后轴向突出的所述弹性可扩展的轴环中的另一个。所述轴环被配置为弹性地卡接到所述轴承的过盈元件上，通过所述轴环与所述轴承的啮合轴向地将所述第一轴固定到所述箱架并且允许所述第一轴绕所述轴承旋转。
本公开的另一方面涉及一种用于容置有药筒的穿戴式注射器的模块化驱动机构，其中所述药筒在一端由活塞密封。所述驱动机构包括伸缩式驱动组件和致动器。所述伸缩式驱动组件包括可旋转的第一轴，以及与所述第一轴伸缩式连接并且相对于所述第一轴轴向可移动的第二轴。所述第一轴的旋转将所述第二轴从缩回组态轴向驱动到延伸组态，从而在所述药筒内啮合并推进所述活塞。所述第二轴可旋转地固定。致动器旋转所述伸缩式驱动组件的所述第一轴。箱架在所述注射器内选择性地可固定。所述箱架包括第一套筒和基本与所述第一套筒平行的第二套筒。所述伸缩式驱动可滑动地容置在所述第一套筒内，且所述第一轴轴向地固定到所述第一套筒。所述致动器可滑动地容置在所述第二套筒内。
附图说明
结合附图阅读时，将更好地理解以下详细描述的关于本公开的各个方面。然而，应当理解，本发明不限制于所示的精确布置和机构。在附图中：
图1示出穿戴式注射器的部分透视图，其中固定有根据本公开实施例的模块化驱动机构；
图2是图1的模块化驱动机构的部分分解透视图；
图3是沿图1的剖面线3-3获取的图1的模块化驱动机构的部分剖面图，其伸缩式驱动组件处于延伸组态；
图4A是沿图1中的剖面线4-4获取的图1的模块化驱动机构中的第一套筒剖面图，所述伸缩式驱动组件处于缩回组态；
图4B示出沿图1中的剖面线4-4获取的图1中模块化驱动信息中的所述第一套筒的替代结构的剖面图，所述伸缩式驱动组件的替代结构处于缩回组态；以及
图5是沿图1中的剖面线5-5获取的图1的模块化驱动机构的剖面图。
具体实施方式
以下描述中使用的某些术语仅为方便起见，不受限制。所述“下”、“底部”、“上部”和“上”等描述指定了参照附图图纸方向。根据本公开，所述“向内”、“向外”、“向上”和“向下”实质分别朝向和远离模块化驱动机构的几何中心及其指定部件的方向。除非本文特别规定，否则术语“”、“所述”不限于元素，而是应理解为“至少”的含义，术语包括上述词语、其派生词和类似含义的词语。
还应理解，本公开中使用的术语“近似”、“大约”、“一般”、“基本上”等类似术语表明，所描述的维数/特征不是严格的边界或参数，不排除由此产生的在功能上类似的微小变化。至少，包括数值参数的类似参考将包括使用本领域所接受的数学和工业原理(例如，舍入、测量或其他系统误差、制造公差等)不会改变最低有效数字的变化。
详细参照附图，其中相同的附图标记表示相同的元件，图1-5中示出根据本公开实施例的模块化驱动机构，一般地指定为10。通常，模块化驱动机构10用于穿戴式注射器(贴片注射器)50，例如，没有限制地，穿戴式药物注射器。本领域普通技术人员应当理解，如图1所示，穿戴式注射器通常包括壳体52，壳体52容置其中容纳物质的药筒或储存器54，其中药筒54的一端由活塞54a密封(参见图3)。药筒54可与注射针流体连接，以将药筒54内的物质通过针注射给用户。
如图2所示，在模块化驱动机构10包括箱架12、致动器14、伸缩式驱动组件16、以及传动齿轮18，箱架12选择性地可固定在注射器50的壳体52内。在实施例中，箱架12能够以可移除的方式固定在壳体52内。或者，箱架12可以永久地(即，不可移除地)固定在壳体52内，例如，非限制地，通过粘合或焊接的方式。致动器14和可伸缩驱动组件16安装在箱架12内(下面将进一步详细说明)。在所示的实施例中，致动器14采用马达的形式，但本公开不限于此。例如，致动器14可以采用弹簧致动器、气体致动器、化学致动器、电动致动器、机电致动器或者其组合等形式。致动器14驱动伸缩式驱动组件16的扩张并通过传动齿轮18连接到伸缩驱动组件16(下面将进一步详细说明)。
箱架12包括第一套筒26和第二套筒28，第二套筒28基本平行于第一套筒26，第三套筒30位于第一套筒26和第二套筒28之间。伸缩式驱动组件16可滑动地容置在第一套筒26内，致动器14可滑动地容置在第二套筒28内，传动齿轮18安装到第三套筒30。第二套筒28在尺寸和形状上基本与致动器14相对应。在所示的实施例中，致动器14和第二套筒28分别包括互补的(即，彼此相互作用的)卡接连接部件14a、28a,以可滑动地将致动器14固定并锁定到第二套筒28中。如图2所示，第二套筒28的卡接部件28a采取从第二套筒28的侧壁朝第二套筒28的径向中心逐渐向内突出的柔性构件的形式。柔性构件28a沿致动器14的插入方向进一步逐渐向内延伸。致动器14的卡接部件14a采用径向唇或肩的形式。因此，当致动器14插入第二套筒28时，径向唇14a向外弹性偏置柔性构件28a，在滑过柔性构件28a后，柔性构件28a弹回其原来方向，抵接径向唇14a并将致动器14固定在第二套筒28内，即，防止致动器14在与其插入方向相反的方向上缩回。然而，本领域普通技术人员应当理解，致动器14可以通过当前已知或以后已知的其他耦合方法固定到第二套筒28内。第二套筒28在其尾端还包括停止构件28b从而在致动器14插入时抵接致动器14。在所示实施例中，停止构件28b采用径向向内延伸唇的形式，但本公开不限于此。有利地，不需要用于将致动器14固定在第二套筒28内的额外工具。
对于伸缩式驱动组件16，伸缩式驱动组件16被配置成与活塞54啮合并通过药筒54推进活塞54a，从而将物质从药筒54中推出。美国专利申请号14/725009中描述了伸缩式驱动组件16的一个非限制性示例，其标题为“用于伸缩式注射器阻挡器驱动器驱动组件的线性旋转稳定器”，其全部内容通过引用并入于此。
在所示实施例中，如图3所示，伸缩式驱动组件16包括第一轴20和第二轴22，第二轴22与第一轴20可伸缩地连接，并且相对于第一轴20可轴向移动。第一轴20的旋转轴向驱动第二轴22从缩回组态(图2、4A、4B)至延伸组态(图3)，从而与活塞54啮合并通过药筒54推进活塞54a。在所示的实施例中，如图3所示，可选的第三轴24螺纹连接到第一轴20并螺纹连接到第二轴22，将第一轴20连接到第二轴22。因此，旋转的第一轴20旋转并轴向地驱动第三轴24，转而，第三轴24又轴向驱动第二轴22(下面将进一步说明)。
如图3-5所示，第一轴20容置于并轴向固定到第一套筒26(下面将进一步说明)。伸缩驱动组件16还包括相对于第一套筒26和第二轴22旋转固定并可轴向滑动的防转套筒30。例如，如图5所示，箱架12的第一套筒26基本与防转套筒30同心，防转套筒30基本与第二轴22同心(至少在驱动组件16的缩回组态中)。在所示的实施例中，防转套筒30键接到第一套筒26，第二轴22键接到防转套筒30。特别地，第一套筒26沿着其内侧侧壁限定至少一个轴向延伸的槽32，并且防转套筒30包括至少一个径向向外延伸到槽32中的相应的肋34。沿槽32可滑动的肋34允许防转套筒30相对于箱架12的第一套筒26轴向移动，同时防止他们之间的相对旋转。
类似地，防转套筒30沿着其内侧侧壁限定至少一个轴向延伸槽36，第二轴22包括至少一个径向向外延伸到槽36中的相应肋38。肋38沿槽36可滑动，允许第二轴22相对于防转套筒30轴向运动，同时防止其间的相对转动。因此，第二轴22通过防转套筒30相对于箱架12的第一套筒26可旋转地固定并可轴向滑动。然而，本领域普通技术人员应当理解，第二轴22可以通过当前已知或以后已知的其它耦合方法相对于箱架12可旋转地固定并可轴向滑动。因此，与第一轴20和第二轴22中的每个螺纹连接的第三轴24相对于第一轴20可旋转并可轴向移动。第二轴22相对于第一轴20和第三轴24可轴向移动。因此，第一、第三和第二轴20、24、22形成轴向伸缩式组件。
参见图3-4B，第一套筒26在尺寸和形状上基本对应于伸缩式驱动组件16，以在其中滑动地接收伸缩驱动组件16。如图4A所示，第一套筒26包括轴承40，该轴承40轴向地向前突出，即，从第一套筒26后端向内进入第一套筒26。第一轴20包括从第一轴20的后端轴向地向后突出的相应的弹性可扩张的轴环42。轴环42配置成弹性地卡接在轴承40的过盈元件40b上，即在过盈元件40b上扩张，然后基本上缩回到其初始形态。有利的是，当轴环42与轴承40啮合时，轴承40的位置使伸缩式驱动组件16与第一套筒26自对准，而无需添加连接器或工具。
如图4A所示，轴承40包括基本棒状的芯40a，并且过盈元件40b采用在棒状的芯40a上的至少一个径向向外突出的凸片的形式。在一实施例中，凸片40b可以采用绕棒状的芯40a的环形唇的形式。如图2所示，相应的轴环42基本上是圆筒形的，并且包括多个角度上间隔开且径向向外的柔性弓形构件42a。在所示实施例中，弓形构件42a采用两个正相对的半圆构件42a的形式，但本公开不仅限于此。弓形构件42a在啮合凸片40b时径向地向外弹性地弯曲，并弹回在40b，以将第一轴20固定到第一套筒26。或者，轴环42可以采用基本上连续的圆筒形式，归因于其材料特性至少部分地可弹性扩展。轴环42与轴承40的啮合允许第一轴20绕轴承40旋转，以驱动伸缩式驱动组件16，同时在伸缩式驱动组件16的轴向扩展过程(以推进活塞54a)中或伸缩式驱动组件16轴向缩回过程中轴向地将第一轴20固定到第一套筒26。也就是说，第一轴20相对于第三轴24的旋转导致第三轴24轴向地向前推进，并且第三轴24相对于第二轴22的旋转导致第二轴22轴向向前移动。
如图3-4A所示，轴承40限定棒状的芯40a的基本平坦的前端40c。相反，轴环42的内封闭端42b(与轴环42的外开放端相对)限定朝向外开放端的凸面。当轴环42卡接到轴承40上时，轴环42的内封闭端42b的凸面的顶点接触轴承40的基本平坦前端40c。因此，轴环42和轴承40之间的接触有利地最小化，从而减少第一轴20旋转期间产生的旋转摩擦。本领域普通技术人员应当理解的是，轴环42的封闭端可替代地定义基本平坦表面，轴承40的端面40c可定义朝向套环42的封闭端42b的凸面，从而实现轴承40和轴环42之间的相同接触关系。
如图4B所示，第一套筒26可替代地包括从其后端轴向向前突出到第一套筒26内的弹性可扩展轴环42，并且第一轴20可包括从第一轴20的后端轴向向后突出的相应的轴承40。轴环42的封闭端42b可以定义基本平坦的表面，轴承40的端面40c可以定义朝向轴环42的封闭端42b的凸面，从而实现轴承40和轴环42之间的相同接触关系。然而，本领域普通技术人员应当理解，轴承40可以限定基本平坦的端面40c，轴环42的封闭端42b可以限定朝向轴承40的平面端面40c的凸面。
如图1-3所示，箱架12的第二套筒28限定至少部分开放的前端和后端，使得固定在其中的致动器14可以在任一端啮合其他操作部件。当致动器14固定在套筒28内时，致动器14的致动器齿轮14b与第二套筒28的后端相邻定位，并与传动齿轮18啮合。第一轴20还包括与轴环42的内封闭端42b相邻的伸缩组件旋转齿轮44。传动齿轮18通过第一套筒26中的开口46啮合旋转齿轮44。因此，致动器14操作上与伸缩式驱动组件16啮合。
在操作中，致动器14、伸缩式驱动组件16和传动齿轮18以前面公开的方式固定在箱架12内。当固定到箱架12时，致动器14与伸缩式驱动组件16操作上啮合，使得致动器齿轮14b的旋转驱动伸缩式驱动组件16。当模块化驱动机构10固定到壳体52时，伸缩式驱动组件16与药筒54的隔仓/轨道对准。一旦药筒54被插入其隔仓/轨道中，并且注射器50被激活，则致动器14驱动伸缩式驱动系统16扩展、与活塞54a啮合并推进活塞54a向前通过药筒54从而从药筒54推出药物。
有利地，致动器14、伸缩式驱动组件16和传动齿轮18每个都可在没有工具的情况下轴向插入箱架12(如上所述，通过各自的卡接机构)。更有利的是，驱动机构10的装配可以在注射器50外部进行，并且组装好的驱动机构10可以作为单个模块单元固定到注射器50中。更有利的是，伸缩式驱动组件16、传动齿轮18和箱架12可以由模制聚合物(例如，塑料零件)构成。
本领域技术人员应当理解，可以在不脱离其广泛发明构思的情况下对上述实施例进行修改。因此可以理解，本公开不限于所公开的特定实施例，而是意在涵盖所附权利要求阐明的本发明的精神和范围内的修改。
Claims (20)
1.一种用于容置有药筒的穿戴式注射器的模块化驱动机构，其中所述药筒在一端由活塞密封，所述驱动机构包括：
在所述注射器内选择性地可固定的箱架；以及
安装在所述箱架内的伸缩式驱动组件，所述伸缩式驱动组件包括：
相对于所述箱架可旋转的第一轴，以及；
与所述第一轴伸缩式连接并且相对于所述第一轴轴向可移动的第二轴，其中所述第一轴的旋转将所述第二轴从缩回组态轴向驱动到延伸组态，从而在所述药筒内啮合并推进所述活塞，所述第二轴相对于所述箱架可旋转地固定；
其中所述箱架包括轴承和从所述箱架的后端向前轴向突出到所述箱架中的弹性可扩展的轴环之一，且其中所述第一轴包括所述轴承和从所述第一轴的后端向后轴向突出的所述弹性可扩展的轴环中的另一个，所述轴环被配置为弹性地卡接到所述轴承的过盈元件上，通过所述轴环与所述轴承的啮合轴向地将所述第一轴固定到所述箱架并且允许所述第一轴绕所述轴承旋转。
2.根据权利要求1所述的模块化驱动机构，其中所述轴承包括基本上棒状的芯以及且所述轴承的所述过盈元件包括所述棒状的芯上的至少一个径向外向突出的凸片。
3.根据权利要求2所述的模块化驱动机构，其中所述轴环基本上为圆筒形。
4.根据权利要求3所述的模块化驱动机构，其中所述轴环包括多个角度上间隔开且径向上柔性的弓形构件。
5.根据权利要求1所述的模块化驱动机构，其中所述轴承基本上为棒状并限定基本平坦的前端，且其中所述轴环基本上为圆筒形并包括封闭端和开放端，所述封闭端限定朝向所述轴承的所述平坦的前端的凸面，其中所述轴环的所述封闭端的所述凸面的顶点配置成当所述轴环卡接到所述轴承上时接触所述轴承的所述基本平坦的前端，从而减少两者之间的接触并进而减少旋转摩擦。
6.根据权利要求1所述的模块化驱动机构，其中所述轴环基本上为圆筒形并且包括基本平坦的封闭端和开放端，且所述轴承基本上为棒状并限定朝向所述轴环的所述平坦的封闭端的凸端面，其中，所述轴承的所述凸端面的顶点配置成当所述轴环卡接到所述轴承上时接触所述轴环的基本平坦的封闭端，从而减少两者之间的接触并进而减少旋转摩擦。
7.根据权利要求1所述的模块化驱动机构，其中所述箱架包括第一套筒，且所述轴承从所述第一套筒的后端轴向地向前突出到所述第一套筒，所述伸缩式驱动组件可滑动地容置在所述第一套筒内。
8.根据权利要求7所述的模块化驱动机构，其中所述第二轴可旋转地固定到所述第一套筒。
9.根据权利要求7所述的模块化驱动机构，还包括致动器，用于旋转所述伸缩式驱动组件的所述第一轴，且所述箱架还包括第二套筒，所述致动器可滑动地容置在所述第二套筒内。
10.根据权利要求9所述的模块化驱动机构，其中所述第二套筒以及所述致动器包括互补的卡接连接部件，从而将所述致动器可滑动地固定并锁定在所述第二套筒内。
11.根据权利要求9所述的模块化驱动机构，还包括传动齿轮，所述传动齿轮连接所述致动器和所述伸缩式驱动组件的所述第一轴，且所述箱架还包括第三套筒，所述传动齿轮安装到所述第三套筒。
12.根据权利要求1所述的模块化驱动机构，其中所述伸缩式驱动组件还包括第三轴，所述第三轴连接所述第一轴和所述第二轴，所述第三轴螺纹连接至所述第一轴且螺纹连接至所述第二轴，所述第三轴相对于所述第一轴可旋转且可轴向移动，并且所述第二轴相对于所述第一轴和第三轴可轴向移动，且其中所述伸缩式驱动组件还包括防转套筒，所述防转套筒相对于所述箱架可旋转地固定并可轴向滑动且相对于所述第二轴可旋转地固定并可轴向滑动。
13.一种用于容置有药筒的穿戴式注射器的模块化驱动机构，其中所述药筒在一端由活塞密封，所述驱动机构包括：
伸缩式驱动组件，所述伸缩式驱动组件包括：
可旋转的第一轴可旋转，以及
第二轴，与所述第一轴伸缩式连接并且相对于所述第一轴轴向可移动，其中所述第一轴的旋转将所述第二轴从缩回组态轴向驱动到延伸组态，从而在所述药筒内啮合并推进所述活塞，所述第二轴可旋转地固定；
致动器，用于旋转所述伸缩式驱动组件的所述第一轴，以及
箱架，在所述注射器内选择性地可固定，所述箱架包括：
第一套筒，所述伸缩式驱动可滑动地容置在所述第一套筒内，且所述第一轴轴向地固定到所述第一套筒，以及
第二套筒，基本与所述第一套筒平行，所述致动器可滑动地容置在所述第二套筒内。
14.根据权利要求13所述的模块化驱动机构，还包括传动齿轮，所述传动齿轮连接所述致动器和所述伸缩式驱动组件的所述第一轴，且其中所述箱架还包括连接所述第一和第二套筒的第三套筒，所述传动齿轮安装到所述第三套筒。
15.根据权利要求14所述的模块化驱动机构，其中所述第一轴包括伸缩式组件旋转齿轮且所述第一套筒包括相邻的开口，所述传动齿轮通过所述开口与所述伸缩式组件旋转齿轮啮合。
16.根据权利要求15所述的模块化驱动机构，其中所述第二轴限定开放前端和开放后端，所述致动器包括与所述开放后端相邻定位的致动器齿轮，所述致动器齿轮与所述传动齿轮啮合。
17.根据权利要求13所述的模块化驱动机构，其中所述第二套筒和所述致动器包括互补的卡接连接部件，从而将所述致动器可滑动地固定并锁定在所述第二套筒内。
18.根据权利要求13所述的模块化驱动机构，其中所述第一套筒包括轴承和从所述第一套筒的封闭后端向前轴向突出到所述第一套筒中的弹性可扩展的轴环之一，且其中所述第一轴包括所述轴承和从所述第一轴的后端向后轴向突出的所述弹性可扩展的轴环中的另一个，所述轴环被配置为弹性地卡接到所述轴承的过盈元件上，通过所述轴环与所述轴承的啮合轴向地将所述第一轴固定到所述第一套筒并且允许所述第一轴绕所述轴承旋转。
19.根据权利要求18所述的模块化驱动机构，其中所述轴承包括基本上棒状的芯以及且所述轴承的所述过盈元件包括所述棒状的芯上的至少一个径向外向突出的凸片。
20.根据权利要求18所述的模块化驱动机构，其中所述轴承基本上为棒状并限定基本平坦的前端，且其中所述轴环基本上为圆筒形并包括封闭端和开放端，所述封闭端限定朝向所述轴承的所述平坦的前端的凸面，其中所述轴环的所述封闭端的所述凸面的顶点配置成当所述轴环卡接到所述轴承上时接触所述轴承的所述基本平坦的前端，从而减少两者之间的接触并进而减少旋转摩擦。
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| WO2022105466A1 (zh) * | 2020-11-18 | 2022-05-27 | 洁霺生医科技股份有限公司 | 多段式气体致动供药装置及方法 |
| TWI806182B (zh) * | 2020-11-18 | 2023-06-21 | 潔霺生醫科技股份有限公司 | 多段式氣體致動供藥裝置及方法 |
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Also Published As
| Publication number | Publication date |
|---|---|
| JP6921997B2 (ja) | 2021-08-18 |
| JP2020521579A (ja) | 2020-07-27 |
| EP3630226A1 (en) | 2020-04-08 |
| WO2018222521A1 (en) | 2018-12-06 |
| US11819666B2 (en) | 2023-11-21 |
| CN110869072B (zh) | 2021-12-10 |
| US20210138157A1 (en) | 2021-05-13 |
| CN113855913A (zh) | 2021-12-31 |
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