US5643889A
(en)
*
|
1984-07-11 |
1997-07-01 |
Temple University-Of The Commonwealth System Of Pennsylvania |
Cholesterol conjugates of 2'5'-oligoadenylate derivatives and antiviral uses thereof
|
US5550111A
(en)
*
|
1984-07-11 |
1996-08-27 |
Temple University-Of The Commonwealth System Of Higher Education |
Dual action 2',5'-oligoadenylate antiviral derivatives and uses thereof
|
US5108921A
(en)
*
|
1989-04-03 |
1992-04-28 |
Purdue Research Foundation |
Method for enhanced transmembrane transport of exogenous molecules
|
US5688488A
(en)
*
|
1989-04-03 |
1997-11-18 |
Purdue Research Foundation |
Composition and method for tumor imaging
|
US6753423B1
(en)
|
1990-01-11 |
2004-06-22 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for enhanced biostability and altered biodistribution of oligonucleotides in mammals
|
US6153737A
(en)
*
|
1990-01-11 |
2000-11-28 |
Isis Pharmaceuticals, Inc. |
Derivatized oligonucleotides having improved uptake and other properties
|
US6395492B1
(en)
*
|
1990-01-11 |
2002-05-28 |
Isis Pharmaceuticals, Inc. |
Derivatized oligonucleotides having improved uptake and other properties
|
US6114513A
(en)
|
1990-01-11 |
2000-09-05 |
Isis Pharmaceuticals, Inc. |
Thiol-derivatized oligonucleotides
|
US7037646B1
(en)
|
1990-01-11 |
2006-05-02 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
US20040142899A1
(en)
*
|
1990-01-11 |
2004-07-22 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for enhanced biostability and altered biodistribution of oligonucleotides in mammals
|
AU2160992A
(en)
*
|
1991-06-05 |
1993-01-12 |
Board Of Regents Acting For And On Behalf Of The University Of Michigan, The |
Targeted delivery of genes encoding secretory proteins
|
US6287792B1
(en)
*
|
1991-06-17 |
2001-09-11 |
The Regents Of The University Of California |
Drug delivery of antisense oligonucleotides and peptides to tissues in vivo and to cells using avidin-biotin technology
|
NZ244306A
(en)
*
|
1991-09-30 |
1995-07-26 |
Boehringer Ingelheim Int |
Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
|
US5254342A
(en)
*
|
1991-09-30 |
1993-10-19 |
University Of Southern California |
Compositions and methods for enhanced transepithelial and transendothelial transport or active agents
|
US5981273A
(en)
*
|
1991-09-30 |
1999-11-09 |
Boehringer Ingelheim Int'l. Gmbh |
Composition comprising an endosomolytic agent for introducing nucleic acid complexes into higher eucaryotic cells
|
US6335434B1
(en)
|
1998-06-16 |
2002-01-01 |
Isis Pharmaceuticals, Inc., |
Nucleosidic and non-nucleosidic folate conjugates
|
US6831166B2
(en)
*
|
1992-10-23 |
2004-12-14 |
Isis Pharmaceuticals, Inc. |
Derivatized oligonucleotides having improved uptake and other properties
|
US6033884A
(en)
*
|
1992-03-20 |
2000-03-07 |
Baylor College Of Medicine |
Nucleic acid transporter systems and methods of use
|
CA2131620A1
(en)
*
|
1992-03-20 |
1993-09-30 |
Louis C. Smith |
A dna transporter system and method of use
|
WO1994004194A1
(en)
*
|
1992-08-14 |
1994-03-03 |
Massachusetts Institute Of Technology |
Nucleic acid recognition and transport
|
US20020173474A1
(en)
*
|
1993-02-12 |
2002-11-21 |
President And Fellows Of Harvard College |
Methods & materials involving dimerization-mediated regulation of biological events
|
US5993860A
(en)
*
|
1993-06-17 |
1999-11-30 |
Venture Lending |
NSADI delivery employing a powdered hydrocolloid gum obtainable from higher plants
|
CA2170869C
(en)
|
1993-09-03 |
1999-09-14 |
Phillip Dan Cook |
Amine-derivatized nucleosides and oligonucleosides
|
US6653458B1
(en)
|
1993-09-03 |
2003-11-25 |
Isis Pharmaceuticals, Inc. |
Modified oligonucleotides
|
US5635385A
(en)
*
|
1993-09-15 |
1997-06-03 |
Temple University-Of The Commonwealth System Of Higher Education |
Multi-unit ribozyme inhibition of oncogene gene expression
|
US5844107A
(en)
*
|
1994-03-23 |
1998-12-01 |
Case Western Reserve University |
Compacted nucleic acids and their delivery to cells
|
EP0752005B1
(de)
*
|
1994-03-23 |
2008-10-08 |
Ohio University |
Kompaktnukleinsäure und ihre verabreichung in zellen
|
US5972901A
(en)
|
1994-03-23 |
1999-10-26 |
Case Western Reserve University |
Serpin enzyme complex receptor--mediated gene transfer
|
US6077835A
(en)
*
|
1994-03-23 |
2000-06-20 |
Case Western Reserve University |
Delivery of compacted nucleic acid to cells
|
US5837523A
(en)
*
|
1994-05-05 |
1998-11-17 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of treating tumors
|
US5670347A
(en)
|
1994-05-11 |
1997-09-23 |
Amba Biosciences Llc |
Peptide-mediated gene transfer
|
ATE268186T1
(de)
*
|
1994-06-06 |
2004-06-15 |
Thejmde Trust |
Biotinverbindungen zum zielen auf tumore und infektionsherde
|
US5716594A
(en)
*
|
1994-06-06 |
1998-02-10 |
The Jmde Trust |
Biotin compounds for targetting tumors and sites of infection
|
US5837533A
(en)
*
|
1994-09-28 |
1998-11-17 |
American Home Products Corporation |
Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent
|
JPH10507915A
(ja)
|
1994-10-19 |
1998-08-04 |
ヒューマン ジノーム サイエンシーズ, インコーポレイテッド |
ヒトヒポキサンチン−(グアニン)ホスホリボシルトランスフェラーゼ−2
|
IL114615A0
(en)
|
1995-07-16 |
1995-11-27 |
Yeda Res & Dev |
Modulators of the function of fas receptors and other proteins
|
EP0888128A2
(de)
|
1995-02-10 |
1999-01-07 |
The Worcester Foundation For Biomedical Research |
Abgabe von exogenen verbindungen
|
US5846743A
(en)
*
|
1995-02-22 |
1998-12-08 |
Brigham And Women's Hospital, Inc. |
Polyphoshoinositide binding peptides for intracellular drug delivery
|
US5674748A
(en)
|
1995-03-14 |
1997-10-07 |
Thomas Jefferson University |
Human cyclin-dependent kinase-like proteins and methods of using the same
|
US5547668A
(en)
*
|
1995-05-05 |
1996-08-20 |
The Board Of Trustees Of The University Of Illinois |
Conjugates of folate anti-effector cell antibodies
|
US5672500A
(en)
*
|
1995-05-18 |
1997-09-30 |
Thomas Jefferson University |
Mch2, an apoptotic cysteine protease, and compositions for making and methods of using the same
|
US6420549B1
(en)
|
1995-06-06 |
2002-07-16 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide analogs having modified dimers
|
US5817789A
(en)
|
1995-06-06 |
1998-10-06 |
Transkaryotic Therapies, Inc. |
Chimeric proteins for use in transport of a selected substance into cells
|
WO1997007827A1
(en)
*
|
1995-08-22 |
1997-03-06 |
Thomas Jefferson University |
Gab1, A Grb2 BINDING PROTEIN, AND COMPOSITIONS FOR MAKING AND METHODS OF USING THE SAME
|
US20030119724A1
(en)
*
|
1995-11-22 |
2003-06-26 |
Ts`O Paul O.P. |
Ligands to enhance cellular uptake of biomolecules
|
CA2279675A1
(en)
*
|
1995-12-15 |
1997-06-16 |
Enzo Therapeutics, Inc. |
Property effecting and/or property exhibiting constructs for localizing a nucleic acid construct within a cell for therapeutic and diagnostic uses
|
US6392069B2
(en)
|
1996-01-08 |
2002-05-21 |
Canji, Inc. |
Compositions for enhancing delivery of nucleic acids to cells
|
US7002027B1
(en)
|
1996-01-08 |
2006-02-21 |
Canji, Inc. |
Compositions and methods for therapeutic use
|
US20040014709A1
(en)
*
|
1996-01-08 |
2004-01-22 |
Canji, Inc. |
Methods and compositions for interferon therapy
|
US6344436B1
(en)
|
1996-01-08 |
2002-02-05 |
Baylor College Of Medicine |
Lipophilic peptides for macromolecule delivery
|
US5789244A
(en)
*
|
1996-01-08 |
1998-08-04 |
Canji, Inc. |
Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems
|
US6180767B1
(en)
|
1996-01-11 |
2001-01-30 |
Thomas Jefferson University |
Peptide nucleic acid conjugates
|
US6060587A
(en)
|
1996-01-29 |
2000-05-09 |
The Trustees Of The University Of Pennsylvania |
Cellular receptor for HIV-1 VPR essential for G2/M phase transition of the cell cycle
|
US5783566A
(en)
*
|
1996-05-10 |
1998-07-21 |
California Institute Of Technology |
Method for increasing or decreasing transfection efficiency
|
CA2174803C
(en)
*
|
1996-04-23 |
2000-07-11 |
Jonathan P. Wong |
Use of liposome encapsulated ciprofloxacin as an immunotherapeutic drug
|
US6072041A
(en)
|
1996-06-03 |
2000-06-06 |
Case Western Reserve University |
Fusion proteins for protein delivery
|
US6261787B1
(en)
|
1996-06-03 |
2001-07-17 |
Case Western Reserve University |
Bifunctional molecules for delivery of therapeutics
|
US6310052B1
(en)
|
1996-06-04 |
2001-10-30 |
Queen's University At Kingston |
Nitrate esters and their use for neurological conditions
|
JPH09324000A
(ja)
*
|
1996-06-05 |
1997-12-16 |
Suntory Ltd |
インターロイキン−2受容体を特異的に認識する因子とリボヌクレアーゼとの接合体
|
US20050042647A1
(en)
*
|
1996-06-06 |
2005-02-24 |
Baker Brenda F. |
Phosphorous-linked oligomeric compounds and their use in gene modulation
|
US9096636B2
(en)
|
1996-06-06 |
2015-08-04 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
US20050119470A1
(en)
*
|
1996-06-06 |
2005-06-02 |
Muthiah Manoharan |
Conjugated oligomeric compounds and their use in gene modulation
|
US20070275921A1
(en)
*
|
1996-06-06 |
2007-11-29 |
Isis Pharmaceuticals, Inc. |
Oligomeric Compounds That Facilitate Risc Loading
|
US5898031A
(en)
|
1996-06-06 |
1999-04-27 |
Isis Pharmaceuticals, Inc. |
Oligoribonucleotides for cleaving RNA
|
US7812149B2
(en)
|
1996-06-06 |
2010-10-12 |
Isis Pharmaceuticals, Inc. |
2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
|
WO2005121368A1
(en)
*
|
2004-06-03 |
2005-12-22 |
Isis Pharmaceuticals, Inc. |
Chimeric gapped oligomeric compositions
|
US20040171031A1
(en)
*
|
1996-06-06 |
2004-09-02 |
Baker Brenda F. |
Sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation
|
US6797276B1
(en)
|
1996-11-14 |
2004-09-28 |
The United States Of America As Represented By The Secretary Of The Army |
Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
|
AU7737196A
(en)
*
|
1996-11-14 |
1998-06-03 |
Brigham And Women's Hospital |
Polyphosphoinositide binding peptides for intracellular drug delivery
|
US5980898A
(en)
*
|
1996-11-14 |
1999-11-09 |
The United States Of America As Represented By The U.S. Army Medical Research & Material Command |
Adjuvant for transcutaneous immunization
|
US20060002959A1
(en)
*
|
1996-11-14 |
2006-01-05 |
Government Of The United States |
Skin-sctive adjuvants for transcutaneous immuization
|
US20060002949A1
(en)
*
|
1996-11-14 |
2006-01-05 |
Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. |
Transcutaneous immunization without heterologous adjuvant
|
CA2277519A1
(en)
|
1997-01-10 |
1998-07-16 |
Massachusetts Institute Of Technology |
Treatments for neurotoxicity in alzheimer's disease by .beta.-amyloid peptides
|
US6942963B1
(en)
|
1997-01-10 |
2005-09-13 |
Massachusetts Institute Of Technology |
Methods for identifying treatments for neurotoxicity in Alzheimer's disease caused by β-amyloid peptides
|
JP3816111B2
(ja)
|
1997-04-09 |
2006-08-30 |
インテレクト・ニューロサイエンシズ・インコーポレーテッド |
β−アミロイド末端に特異的な組換え抗体、それをコードするDNA及びその使用法
|
US6716625B1
(en)
|
1997-04-16 |
2004-04-06 |
Claude Selitrennikoff |
Histidine kinases of Aspergillus and other fungal species, related compositions, and methods of use
|
US6037461A
(en)
|
1997-05-20 |
2000-03-14 |
Thomas Jefferson University |
FADD-like anti-apoptotic molecules, methods of using the same, and compositions for and methods of making the same
|
CA2294988C
(en)
|
1997-07-01 |
2015-11-24 |
Isis Pharmaceuticals Inc. |
Compositions and methods for the delivery of oligonucleotides via the alimentary canal
|
WO1999013896A1
(en)
|
1997-09-18 |
1999-03-25 |
The Trustees Of The University Of Pennsylvania |
Attenuated vif dna immunization cassettes for genetic vaccines
|
US6417160B1
(en)
|
1997-10-14 |
2002-07-09 |
Nadine A. Tatton |
Methods for increasing schwann cell survival
|
GB9721901D0
(en)
|
1997-10-16 |
1997-12-17 |
Univ Manchester |
Particles
|
US20040258703A1
(en)
*
|
1997-11-14 |
2004-12-23 |
The Government Of The Us, As Represented By The Secretary Of The Army |
Skin-active adjuvants for transcutaneous immunization
|
WO1999039744A1
(en)
*
|
1998-02-10 |
1999-08-12 |
The Ohio State University Research Foundation |
Compositions and methods for polynucleotide delivery
|
US20040002079A1
(en)
*
|
1998-02-11 |
2004-01-01 |
Gunn Robert B. |
Sodium-phosphate cotransporter in lithium therapy for the treatment of mental illness
|
US20020137786A1
(en)
*
|
1998-02-12 |
2002-09-26 |
William G. Tatton |
Deprenyl compounds to treat viral infections and reduce tissue damage associated therewith
|
US20090011984A1
(en)
*
|
1998-02-23 |
2009-01-08 |
Seppo Yla-Herttuala |
Biotin-binding receptor molecules
|
US6417168B1
(en)
|
1998-03-04 |
2002-07-09 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of treating tumors
|
US6329356B1
(en)
|
1998-04-10 |
2001-12-11 |
Neurochem, Inc. |
Phosphono-carboxylate compounds for treating amyloidosis
|
US6093382A
(en)
|
1998-05-16 |
2000-07-25 |
Bracco Research Usa Inc. |
Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
|
WO1999060012A1
(en)
*
|
1998-05-21 |
1999-11-25 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for non-parenteral delivery of oligonucleotides
|
US6300319B1
(en)
|
1998-06-16 |
2001-10-09 |
Isis Pharmaceuticals, Inc. |
Targeted oligonucleotide conjugates
|
US20030219427A1
(en)
*
|
1998-08-18 |
2003-11-27 |
Allen Hamish J. |
TPL-2/COT kinase and methods of use
|
US6077709A
(en)
|
1998-09-29 |
2000-06-20 |
Isis Pharmaceuticals Inc. |
Antisense modulation of Survivin expression
|
US6448078B1
(en)
|
1998-10-09 |
2002-09-10 |
The Trustees Of The University Of Pennsylvania |
Cellular receptor for HIV-1 Vpr essential for G2/M phase transition of the cell cycle
|
ATE483816T1
(de)
|
1998-11-19 |
2010-10-15 |
Univ Georgetown |
Systemisches virus/ligand genabgabemittel und gentherapie
|
US20050063950A1
(en)
*
|
1998-11-19 |
2005-03-24 |
Georgetown University |
Systemic viral/ligand gene delivery system and gene therapy
|
WO2000035422A2
(en)
*
|
1998-12-18 |
2000-06-22 |
Hadasit Medical Research Services & Development Ltd. |
Method of administering a compound to multi-drug resistant cells
|
US6974698B1
(en)
|
1999-01-15 |
2005-12-13 |
The United States Of America As Represented By The Department Of Health And Human Services |
Methods for delivering biologically active molecules into cells
|
EP1216309A2
(de)
*
|
1999-03-01 |
2002-06-26 |
Variagenics, Inc. |
Verfahren zum auffinden von molekülen, die an rns binden
|
US6713280B1
(en)
|
1999-04-07 |
2004-03-30 |
Thomas Jefferson University |
Enhancement of peptide cellular uptake
|
US7098192B2
(en)
|
1999-04-08 |
2006-08-29 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of STAT3 expression
|
AU4188100A
(en)
*
|
1999-04-08 |
2000-11-14 |
Gregory M. Glenn |
Dry formulation for transcutaneous immunization
|
GB9908195D0
(en)
|
1999-04-09 |
1999-06-02 |
Microbiological Res Authority |
Treatment of intracellular infection
|
IL146143A0
(en)
*
|
1999-04-28 |
2002-07-25 |
Univ Kingston |
Compositions and methods for treating amyloidosis
|
US6609113B1
(en)
*
|
1999-05-03 |
2003-08-19 |
The Chase Manhattan Bank |
Method and system for processing internet payments using the electronic funds transfer network
|
AUPQ014699A0
(en)
*
|
1999-05-04 |
1999-05-27 |
Access Pharmaceuticals Australia Pty Limited |
Amplification of folate-mediated targeting to tumor cells using nanoparticles
|
US6562836B1
(en)
*
|
1999-05-24 |
2003-05-13 |
Queen's University Of Kingston |
Methods and compounds for inhibiting amyloid deposits
|
US6656730B1
(en)
*
|
1999-06-15 |
2003-12-02 |
Isis Pharmaceuticals, Inc. |
Oligonucleotides conjugated to protein-binding drugs
|
CA2391348A1
(en)
*
|
1999-07-29 |
2001-02-08 |
Assem Ziady |
Enhanced delivery via serpin enzyme complex receptor
|
MXPA02001911A
(es)
|
1999-08-24 |
2003-07-21 |
Medarex Inc |
Anticuerpos ctla-4 humanos y sus usos.
|
EP1212096A2
(de)
*
|
1999-08-26 |
2002-06-12 |
Sydney Brenner |
Arzneimittelkonjugate und verfahren zur herstellung
|
US6692724B1
(en)
|
1999-10-25 |
2004-02-17 |
Board Of Regents, The University Of Texas System |
Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
|
US7067111B1
(en)
*
|
1999-10-25 |
2006-06-27 |
Board Of Regents, University Of Texas System |
Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
|
CA2391534A1
(en)
*
|
1999-11-15 |
2001-05-25 |
Drug Innovation & Design, Inc. |
Selective cellular targeting: multifunctional delivery vehicles
|
US8571975B1
(en)
|
1999-11-24 |
2013-10-29 |
Jpmorgan Chase Bank, N.A. |
System and method for sending money via E-mail over the internet
|
WO2001041784A1
(en)
*
|
1999-12-09 |
2001-06-14 |
The Regents Of The University Of California |
Methods and compositions for use in the treatment of filovirus mediated disease conditions
|
US6933108B2
(en)
*
|
1999-12-09 |
2005-08-23 |
The Regents Of The University Of California |
Methods and compositions for use in the treatment of filovirus mediated disease conditions
|
US20020055479A1
(en)
|
2000-01-18 |
2002-05-09 |
Cowsert Lex M. |
Antisense modulation of PTP1B expression
|
US6261840B1
(en)
|
2000-01-18 |
2001-07-17 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of PTP1B expression
|
GB0002814D0
(en)
|
2000-02-09 |
2000-03-29 |
Univ York |
Nucleic acids and their uses
|
WO2005041859A2
(en)
*
|
2003-04-30 |
2005-05-12 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery.
|
US7833992B2
(en)
*
|
2001-05-18 |
2010-11-16 |
Merck Sharpe & Dohme |
Conjugates and compositions for cellular delivery
|
AU3811101A
(en)
*
|
2000-02-11 |
2001-08-20 |
Lawrence Blatt |
Method and reagent for the modulation and diagnosis of cd20 and nogo gene expression
|
US8202979B2
(en)
*
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
US7491805B2
(en)
*
|
2001-05-18 |
2009-02-17 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
US20030176385A1
(en)
*
|
2000-02-15 |
2003-09-18 |
Jingfang Ju |
Antisense modulation of protein expression
|
US7033594B2
(en)
*
|
2000-03-31 |
2006-04-25 |
Purdue Research Foundation |
Method of treatment using ligand-immunogen conjugates
|
CN1095472C
(zh)
*
|
2000-04-17 |
2002-12-04 |
上海复康医药科技发展有限公司 |
叶酸-多聚糖复合物,其制备方法和以该复合物为活性成分的药物组合物
|
US7560534B2
(en)
|
2000-05-08 |
2009-07-14 |
Celldex Research Corporation |
Molecular conjugates comprising human monoclonal antibodies to dendritic cells
|
KR100881471B1
(ko)
|
2000-05-08 |
2009-02-05 |
셀덱스 쎄라퓨틱스, 인크. |
수상세포에 대한 인간 모노클로날 항체
|
US6680172B1
(en)
|
2000-05-16 |
2004-01-20 |
Regents Of The University Of Michigan |
Treatments and markers for cancers of the central nervous system
|
BRPI0111220B8
(pt)
*
|
2000-06-02 |
2021-07-27 |
Univ Texas |
conjugados de fármacos com etilenodicisteína (ec)
|
US20080032942A1
(en)
*
|
2000-08-30 |
2008-02-07 |
Mcswiggen James |
RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
|
US20050209179A1
(en)
*
|
2000-08-30 |
2005-09-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
|
EP1341497A4
(de)
*
|
2000-11-02 |
2005-10-19 |
Smithkline Beecham Corp |
Rezeptor-antagonisten-lipid-konjugate und diese enthaltende abgabeträger
|
US7067550B2
(en)
*
|
2000-11-03 |
2006-06-27 |
Massachusetts Institute Of Technology |
Treatments for neurotoxicity in Alzheimer's Disease
|
WO2002035987A2
(en)
*
|
2000-11-03 |
2002-05-10 |
Massachusetts Institute Of Technology |
METHODS FOR IDENTIFYING TREATMENTS FOR NEUROTOXICITY IN ALZHEIMER'S DISEASE CAUSED BY β-AMYLOID PEPTIDES
|
EP1355672A2
(de)
|
2000-12-01 |
2003-10-29 |
Cell Works Inc. |
"konjugate von glykosylierten/galaktosylierten peptiden, bifunktionellen linkern und nukleotid?monomeren/polymeren, damit zusammenhängende zusammensetzungen, sowie verfahren zu ihrer verwendung"
|
ATE398461T1
(de)
*
|
2001-02-13 |
2008-07-15 |
Us Gov Sec Army |
Impstoffe zur transkutanen immunisierung gegen reisediarrhö
|
DE60231868D1
(de)
*
|
2001-04-24 |
2009-05-20 |
Purdue Research Foundation |
Folat-mimetika und deren folatrezeptorbindende konjugate
|
EP1389090A2
(de)
*
|
2001-04-26 |
2004-02-18 |
Board of Regents, The University of Texas System |
Diagnostische bildgebende zusammensetzungen, ihre syntheseverfahren und ihre verwendung
|
WO2002087424A2
(en)
*
|
2001-05-02 |
2002-11-07 |
Purdue Research Foundation |
Treatment and diagnosis of macrophage mediated disease
|
US20060142226A1
(en)
*
|
2001-05-18 |
2006-06-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cholesteryl ester transfer protein (CETP) gene expression using short interfering nucleic acid (siNA)
|
US20030130186A1
(en)
*
|
2001-07-20 |
2003-07-10 |
Chandra Vargeese |
Conjugates and compositions for cellular delivery
|
US20050222066A1
(en)
*
|
2001-05-18 |
2005-10-06 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20050014172A1
(en)
*
|
2002-02-20 |
2005-01-20 |
Ivan Richards |
RNA interference mediated inhibition of muscarinic cholinergic receptor gene expression using short interfering nucleic acid (siNA)
|
US20050130181A1
(en)
*
|
2001-05-18 |
2005-06-16 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of wingless gene expression using short interfering nucleic acid (siNA)
|
US20050176664A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cholinergic muscarinic receptor (CHRM3) gene expression using short interfering nucleic acid (siNA)
|
US20050119211A1
(en)
*
|
2001-05-18 |
2005-06-02 |
Sirna Therapeutics, Inc. |
RNA mediated inhibition connexin gene expression using short interfering nucleic acid (siNA)
|
EP1572067A4
(de)
|
2001-05-18 |
2009-05-13 |
Sirna Therapeutics Inc |
Konjugate und zusammensetzungen für die zelluläre freisetzung
|
US20050136436A1
(en)
*
|
2001-05-18 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of G72 and D-amino acid oxidase (DAAO) gene expression using short interfering nucleic acid (siNA)
|
US20050288242A1
(en)
*
|
2001-05-18 |
2005-12-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)
|
US20050191638A1
(en)
*
|
2002-02-20 |
2005-09-01 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)
|
US20060211642A1
(en)
*
|
2001-05-18 |
2006-09-21 |
Sirna Therapeutics, Inc. |
RNA inteference mediated inhibition of hepatitis C virus (HVC) gene expression using short interfering nucleic acid (siNA)
|
US20050079610A1
(en)
*
|
2001-05-18 |
2005-04-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA)
|
US7109165B2
(en)
*
|
2001-05-18 |
2006-09-19 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
US20050153914A1
(en)
*
|
2001-05-18 |
2005-07-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of MDR P-glycoprotein gene expression using short interfering nucleic acid (siNA)
|
US20080188430A1
(en)
*
|
2001-05-18 |
2008-08-07 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)
|
US20040198682A1
(en)
*
|
2001-11-30 |
2004-10-07 |
Mcswiggen James |
RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (siNA)
|
US20050182006A1
(en)
*
|
2001-05-18 |
2005-08-18 |
Sirna Therapeutics, Inc |
RNA interference mediated inhibition of protein kinase C alpha (PKC-alpha) gene expression using short interfering nucleic acid (siNA)
|
US7517864B2
(en)
*
|
2001-05-18 |
2009-04-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20080161256A1
(en)
*
|
2001-05-18 |
2008-07-03 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
US20050124566A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)
|
US20050143333A1
(en)
*
|
2001-05-18 |
2005-06-30 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
|
US20060142225A1
(en)
*
|
2001-05-18 |
2006-06-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cyclin dependent kinase-2 (CDK2) gene expression using short interfering nucleic acid (siNA)
|
US20050164968A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of ADAM33 gene expression using short interfering nucleic acid (siNA)
|
US20050287128A1
(en)
*
|
2001-05-18 |
2005-12-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of TGF-beta and TGF-beta receptor gene expression using short interfering nucleic acid (siNA)
|
US20050196765A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of checkpoint Kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)
|
US20050182009A1
(en)
*
|
2001-05-18 |
2005-08-18 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of NF-Kappa B / REL-A gene expression using short interfering nucleic acid (siNA)
|
US20050233344A1
(en)
*
|
2001-05-18 |
2005-10-20 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of platelet derived growth factor (PDGF) and platelet derived growth factor receptor (PDGFR) gene expression using short interfering nucleic acid (siNA)
|
US20050233996A1
(en)
*
|
2002-02-20 |
2005-10-20 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hairless (HR) gene expression using short interfering nucleic acid (siNA)
|
US20050119212A1
(en)
*
|
2001-05-18 |
2005-06-02 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of FAS and FASL gene expression using short interfering nucleic acid (siNA)
|
US20050159379A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc |
RNA interference mediated inhibition of gastric inhibitory polypeptide (GIP) and gastric inhibitory polypeptide receptor (GIPR) gene expression using short interfering nucleic acid (siNA)
|
US20050187174A1
(en)
*
|
2001-05-18 |
2005-08-25 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
|
US20050203040A1
(en)
*
|
2001-05-18 |
2005-09-15 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)
|
US20050164966A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of type 1 insulin-like growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20070270579A1
(en)
*
|
2001-05-18 |
2007-11-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
US20060019913A1
(en)
*
|
2001-05-18 |
2006-01-26 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibtion of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)
|
US20050233997A1
(en)
*
|
2001-05-18 |
2005-10-20 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)
|
US20050196767A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acis (siNA)
|
US9994853B2
(en)
|
2001-05-18 |
2018-06-12 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
US20050176666A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of GPRA and AAA1 gene expression using short interfering nucleic acid (siNA)
|
US20050256068A1
(en)
*
|
2001-05-18 |
2005-11-17 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of stearoyl-CoA desaturase (SCD) gene expression using short interfering nucleic acid (siNA)
|
US20050124567A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of TRPM7 gene expression using short interfering nucleic acid (siNA)
|
US20050227935A1
(en)
*
|
2001-05-18 |
2005-10-13 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of TNF and TNF receptor gene expression using short interfering nucleic acid (siNA)
|
US20050267058A1
(en)
*
|
2001-05-18 |
2005-12-01 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (sINA)
|
US20050159376A1
(en)
*
|
2002-02-20 |
2005-07-21 |
Slrna Therapeutics, Inc. |
RNA interference mediated inhibition 5-alpha reductase and androgen receptor gene expression using short interfering nucleic acid (siNA)
|
US20050153915A1
(en)
*
|
2001-05-18 |
2005-07-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of early growth response gene expression using short interfering nucleic acid (siNA)
|
US20050164224A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)
|
US20050176665A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hairless (HR) gene expression using short interfering nucleic acid (siNA)
|
US20050159382A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)
|
US20050182007A1
(en)
*
|
2001-05-18 |
2005-08-18 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
|
US20070042983A1
(en)
*
|
2001-05-18 |
2007-02-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
US20050080031A1
(en)
*
|
2001-05-18 |
2005-04-14 |
Sirna Therapeutics, Inc. |
Nucleic acid treatment of diseases or conditions related to levels of Ras, HER2 and HIV
|
US20050054598A1
(en)
*
|
2002-02-20 |
2005-03-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition hairless (HR) gene expression using short interfering nucleic acid (siNA)
|
US20050124568A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of acetyl-CoA-carboxylase gene expression using short interfering nucleic acid (siNA)
|
US20050282188A1
(en)
*
|
2001-05-18 |
2005-12-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
US20060241075A1
(en)
*
|
2001-05-18 |
2006-10-26 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of desmoglein gene expression using short interfering nucleic acid (siNA)
|
US20050209180A1
(en)
*
|
2001-05-18 |
2005-09-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hepatitis C virus (HCV) expression using short interfering nucleic acid (siNA)
|
US20040209831A1
(en)
*
|
2002-02-20 |
2004-10-21 |
Mcswiggen James |
RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)
|
US20050137155A1
(en)
*
|
2001-05-18 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of Parkinson disease using short interfering nucleic acid (siNA)
|
US20050164967A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA)
|
US20050159380A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of angiopoietin gene expression using short interfering nucleic acid (siNA)
|
US20050107595A1
(en)
*
|
2001-06-20 |
2005-05-19 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
EP2000545B1
(de)
|
2001-06-20 |
2011-08-31 |
Genentech, Inc. |
Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Lungentumoren
|
US7803915B2
(en)
*
|
2001-06-20 |
2010-09-28 |
Genentech, Inc. |
Antibody compositions for the diagnosis and treatment of tumor
|
WO2003000707A2
(en)
|
2001-06-21 |
2003-01-03 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of superoxide dismutase 1, soluble expression
|
EP1409017A4
(de)
*
|
2001-06-25 |
2006-05-24 |
Drug Innovation & Design Inc |
Zelltargeting, zusammensetzungen, verfahren und krebsbehandlungen auf basis exponentieller mustererkennung
|
US6964950B2
(en)
|
2001-07-25 |
2005-11-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of C-reactive protein expression
|
US7425545B2
(en)
|
2001-07-25 |
2008-09-16 |
Isis Pharmaceuticals, Inc. |
Modulation of C-reactive protein expression
|
US20030096772A1
(en)
|
2001-07-30 |
2003-05-22 |
Crooke Rosanne M. |
Antisense modulation of acyl CoA cholesterol acyltransferase-2 expression
|
US7407943B2
(en)
|
2001-08-01 |
2008-08-05 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein B expression
|
US7227014B2
(en)
|
2001-08-07 |
2007-06-05 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein (a) expression
|
KR101008758B1
(ko)
|
2001-09-18 |
2011-01-14 |
제넨테크, 인크. |
종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물
|
ES2338305T3
(es)
*
|
2001-09-28 |
2010-05-06 |
Purdue Research Foundation |
Metodo de tratamiento que utiliza conjugados ligando-inmunogeno.
|
US6750019B2
(en)
|
2001-10-09 |
2004-06-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of insulin-like growth factor binding protein 5 expression
|
AU2002334895B2
(en)
|
2001-10-09 |
2006-10-19 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of insulin-like growth factor binding protein 5 expression
|
EP2325193A3
(de)
|
2001-11-02 |
2012-05-02 |
Insert Therapeutics, Inc. |
Verfahren und Zusammensetzungen zur therapeutischen Verwendung von RNA-Interferenz
|
US6965025B2
(en)
|
2001-12-10 |
2005-11-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of connective tissue growth factor expression
|
US7261875B2
(en)
*
|
2001-12-21 |
2007-08-28 |
Board Of Regents, The University Of Texas System |
Dendritic poly (amino acid) carriers and methods of use
|
US7255874B1
(en)
|
2001-12-21 |
2007-08-14 |
Closure Medical Corporation |
Biocompatible polymers and adhesives: compositions, methods of making and uses related thereto
|
KR100623128B1
(ko)
|
2002-01-02 |
2006-09-14 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
US8043602B2
(en)
|
2002-02-07 |
2011-10-25 |
Endocyte, Inc. |
Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
|
US8043603B2
(en)
*
|
2002-02-07 |
2011-10-25 |
Endocyte, Inc. |
Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
|
US20050096284A1
(en)
*
|
2002-02-20 |
2005-05-05 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)
|
US9657294B2
(en)
|
2002-02-20 |
2017-05-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
US20050222064A1
(en)
*
|
2002-02-20 |
2005-10-06 |
Sirna Therapeutics, Inc. |
Polycationic compositions for cellular delivery of polynucleotides
|
US9181551B2
(en)
|
2002-02-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
US20050137153A1
(en)
*
|
2002-02-20 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of alpha-1 antitrypsin (AAT) gene expression using short interfering nucleic acid (siNA)
|
US20030191075A1
(en)
*
|
2002-02-22 |
2003-10-09 |
Cook Phillip Dan |
Method of using modified oligonucleotides for hepatic delivery
|
US20030180712A1
(en)
|
2002-03-20 |
2003-09-25 |
Biostratum Ab |
Inhibition of the beta3 subunit of L-type Ca2+ channels
|
DK2264172T3
(da)
|
2002-04-05 |
2017-11-27 |
Roche Innovation Ct Copenhagen As |
Oligomerforbindelser til modulering af HIF-1á-ekspression
|
MXPA04010092A
(es)
|
2002-04-16 |
2004-12-13 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento de tumores.
|
CN1662251B
(zh)
*
|
2002-04-19 |
2012-10-10 |
恩多塞特公司 |
佐剂增强的免疫应用
|
US20030206916A1
(en)
*
|
2002-05-03 |
2003-11-06 |
Rush-Presbyterian-St. Luke's Medical Center |
Immunogenic peptides
|
AU2003266014B2
(en)
|
2002-05-06 |
2009-05-14 |
Alnylam Pharmaceuticals, Inc. |
Methods for delivery of nucleic acids
|
DE60326833D1
(de)
*
|
2002-05-15 |
2009-05-07 |
Endocyte Inc |
Vitamin-mitomycin-konjugate
|
US7199107B2
(en)
|
2002-05-23 |
2007-04-03 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of kinesin-like 1 expression
|
WO2004009779A2
(en)
|
2002-07-19 |
2004-01-29 |
University Of South Carolina |
Compositions and methods for the modulation of gene expression in plants
|
CA2493364A1
(en)
|
2002-07-26 |
2004-02-12 |
Basf Plant Science Gmbh |
Inversion of the negative-selective effect of negative marker proteins using selection methods
|
EP2277551B1
(de)
|
2002-09-06 |
2013-05-08 |
Cerulean Pharma Inc. |
Polymere auf basis von cyclodextrin zur verabreichung von an diese kovalent gebundene arzneimittel
|
EP1537208A1
(de)
|
2002-09-13 |
2005-06-08 |
Replicor, Inc. |
Nicht-sequenzkomplementäre antivirale oligonukleotide
|
EP1549767A4
(de)
|
2002-09-26 |
2006-06-07 |
Amgen Inc |
Modulation der expression von forkhead-box o1a
|
WO2004035607A2
(en)
|
2002-10-17 |
2004-04-29 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
AU2003304203A1
(en)
*
|
2002-10-29 |
2005-01-04 |
Pharmacia Corporation |
Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same
|
WO2004044136A2
(en)
|
2002-11-05 |
2004-05-27 |
Isis Pharmaceuticals, Inc. |
Compositions comprising alternating 2’-modified nucleosides for use in gene modulation
|
EP1560839A4
(de)
|
2002-11-05 |
2008-04-23 |
Isis Pharmaceuticals Inc |
Chimäre oligomere verbindungen und derenverwendung in der genmodulation
|
CA2505537A1
(en)
*
|
2002-11-07 |
2004-05-27 |
Board Of Regents, The University Of Texas System |
Ethylenedicysteine (ec)-drug conjugates, compositions and methods for tissue specific disease imaging
|
WO2004058939A2
(en)
*
|
2002-11-12 |
2004-07-15 |
The Research Foundation Of The State University Of New York |
TRANSLATIONAL CONTROL BY SMALL, NON-TRANSLATABLE RNAs
|
JP4986109B2
(ja)
|
2002-11-13 |
2012-07-25 |
ジェンザイム・コーポレーション |
アポリポタンパク質b発現のアンチセンス調節
|
PT2336318E
(pt)
|
2002-11-13 |
2013-06-12 |
Genzyme Corp |
Modulação anti-sentido da expressão de apolipoproteína b
|
AU2002953073A0
(en)
*
|
2002-11-21 |
2003-01-16 |
Access Pharmaceuticals Australia Pty Limited |
Amplification of biotin-mediated targeting
|
DE10254601A1
(de)
|
2002-11-22 |
2004-06-03 |
Ganymed Pharmaceuticals Ag |
Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
|
US7144999B2
(en)
|
2002-11-23 |
2006-12-05 |
Isis Pharmaceuticals, Inc. |
Modulation of hypoxia-inducible factor 1 alpha expression
|
US20040231231A1
(en)
*
|
2002-12-20 |
2004-11-25 |
Cataldo Dominic A. |
Use of colloidal clays for sustained release of active ingredients
|
EP2529758A3
(de)
|
2003-01-27 |
2013-01-02 |
Endocyte, Inc. |
Vitaminrezeptorbindende Wirkstofffreisetzungskonjugate
|
US7713738B2
(en)
*
|
2003-02-10 |
2010-05-11 |
Enzon Pharmaceuticals, Inc. |
Oligomeric compounds for the modulation of survivin expression
|
WO2004072284A1
(en)
|
2003-02-11 |
2004-08-26 |
Antisense Therapeutics Ltd |
Modulation of insulin like growth factor i receptor expression
|
US7803781B2
(en)
|
2003-02-28 |
2010-09-28 |
Isis Pharmaceuticals, Inc. |
Modulation of growth hormone receptor expression and insulin-like growth factor expression
|
US20040185559A1
(en)
|
2003-03-21 |
2004-09-23 |
Isis Pharmaceuticals Inc. |
Modulation of diacylglycerol acyltransferase 1 expression
|
US7598227B2
(en)
|
2003-04-16 |
2009-10-06 |
Isis Pharmaceuticals Inc. |
Modulation of apolipoprotein C-III expression
|
AU2004231740A1
(en)
*
|
2003-04-17 |
2004-11-04 |
The Trustees Of Columbia University In The City Ofnew York |
Desmoglein 4 is a novel gene involved in hair growth
|
CA2523142A1
(en)
|
2003-04-23 |
2004-11-04 |
Medarex, Inc. |
Humanized antibodies to interferon alpha receptor-1 (ifnar-1)
|
US7399853B2
(en)
|
2003-04-28 |
2008-07-15 |
Isis Pharmaceuticals |
Modulation of glucagon receptor expression
|
CA2524441C
(en)
*
|
2003-05-06 |
2012-03-20 |
Purdue Research Foundation |
Treatment of lupus targeting the macrophages or the folate receptor
|
CA2527196C
(en)
*
|
2003-05-30 |
2012-10-16 |
Purdue Research Foundation |
Diagnostic method for atherosclerosis
|
IL156263A0
(en)
*
|
2003-06-02 |
2004-01-04 |
Hadasit Med Res Service |
Livin-derived peptides, compositions and uses thereof
|
BRPI0410886A
(pt)
|
2003-06-03 |
2006-07-04 |
Isis Pharmaceuticals Inc |
composto de filamento duplo, composição farmacêutica, sal farmaceuticamente aceitável, métodos de modificação do ácido nucleico que codifica a survivina humana, de inibição da expressão da suvivina em células ou tecidos, e de tratamento de uma condição associada com a expressão ou superexpressão da suvivina, e, oligonucleotìdeo de rnai de filamento único
|
CA2527658A1
(en)
*
|
2003-06-04 |
2004-12-16 |
Canji, Inc. |
Methods and compositions for interferon therapy
|
US7754684B2
(en)
*
|
2003-06-11 |
2010-07-13 |
Access Pharmaceuticals, Inc. |
Macromolecular platinum chelates
|
US20070010573A1
(en)
*
|
2003-06-23 |
2007-01-11 |
Xianqi Kong |
Methods and compositions for treating amyloid-related diseases
|
US20050142191A1
(en)
|
2003-06-23 |
2005-06-30 |
Neurochem (International) Limited |
Pharmaceutical formulations of amyloid inhibiting compounds
|
US7244764B2
(en)
*
|
2003-06-23 |
2007-07-17 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
US7414076B2
(en)
*
|
2003-06-23 |
2008-08-19 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
WO2005007673A2
(en)
*
|
2003-07-03 |
2005-01-27 |
Rush University Medical Center |
Immunogenic peptides
|
US7683036B2
(en)
|
2003-07-31 |
2010-03-23 |
Regulus Therapeutics Inc. |
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
|
EP1502954A1
(de)
|
2003-07-31 |
2005-02-02 |
greenovation Biotech GmbH |
Gebrauch von Konstrukten mit rekombinanten Sequenzmotifen zur Erhöhung der Genexpression in Moosen
|
US7825235B2
(en)
|
2003-08-18 |
2010-11-02 |
Isis Pharmaceuticals, Inc. |
Modulation of diacylglycerol acyltransferase 2 expression
|
US20070123480A1
(en)
*
|
2003-09-11 |
2007-05-31 |
Replicor Inc. |
Oligonucleotides targeting prion diseases
|
EP1668130A2
(de)
|
2003-09-18 |
2006-06-14 |
Isis Pharmaceuticals, Inc. |
Modulation der eif4e-expression
|
US7662929B2
(en)
|
2003-10-10 |
2010-02-16 |
Alchemia Oncology Pty Limited |
Antibody that specifically binds hyaluronan synthase
|
US20050191653A1
(en)
|
2003-11-03 |
2005-09-01 |
Freier Susan M. |
Modulation of SGLT2 expression
|
US7601511B2
(en)
*
|
2003-11-12 |
2009-10-13 |
University Of Georgia Research Foundation, Inc. |
Biotin-facilitated transport in gram negative bacteria
|
SI2161283T1
(sl)
|
2003-11-17 |
2014-10-30 |
Genentech, Inc. |
Sestavki, ki obsegajo protitelesa proti CD79b, konjugirana na sredstvo, ki inhibira rast, ali na citotoksično sredstvo, in postopki za zdravljenje tumorja hematopoetskega izvora
|
US20050118124A1
(en)
*
|
2003-12-01 |
2005-06-02 |
Reinhart Gale M. |
Compositions for treating keratinous surfaces
|
KR101374514B1
(ko)
|
2003-12-10 |
2014-03-13 |
메다렉스, 인코포레이티드 |
Ip―10 항체 및 그의 용도
|
DK2418220T3
(da)
|
2003-12-10 |
2017-11-06 |
Squibb & Sons Llc |
Interferon-alpha-antistoffer og anvendelser deraf
|
US9050378B2
(en)
*
|
2003-12-10 |
2015-06-09 |
Board Of Regents, The University Of Texas System |
N2S2 chelate-targeting ligand conjugates
|
FR2864085B1
(fr)
*
|
2003-12-18 |
2010-09-17 |
Centre Nat Rech Scient |
Nouveaux modulateurs du proteasome
|
US7622453B2
(en)
|
2003-12-23 |
2009-11-24 |
Santaris Pharma A/S |
Oligomeric compounds for the modulation of Bcl-2
|
US20050164271A1
(en)
|
2004-01-20 |
2005-07-28 |
Sanjay Bhanot |
Modulation of glucocorticoid receptor expression
|
EP1732608A2
(de)
*
|
2004-01-22 |
2006-12-20 |
Immunomedics, Inc. |
Folatkonjugate und komplexe
|
US7468431B2
(en)
|
2004-01-22 |
2008-12-23 |
Isis Pharmaceuticals, Inc. |
Modulation of eIF4E-BP2 expression
|
EP1713900A4
(de)
*
|
2004-01-27 |
2009-06-17 |
Compugen Ltd |
Verfahren und systeme zur kommentierung biomolekularer sequenzen
|
US20050232919A1
(en)
*
|
2004-02-12 |
2005-10-20 |
Morphotek, Inc. |
Monoclonal antibodies that specifically block biological activity of a tumor antigen
|
US8569474B2
(en)
|
2004-03-09 |
2013-10-29 |
Isis Pharmaceuticals, Inc. |
Double stranded constructs comprising one or more short strands hybridized to a longer strand
|
US8790919B2
(en)
|
2004-03-15 |
2014-07-29 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for optimizing cleavage of RNA by RNase H
|
NZ550705A
(en)
|
2004-03-22 |
2010-12-24 |
Kode Biotech Ltd |
Synthetic membrane anchors
|
US10858384B2
(en)
|
2004-03-22 |
2020-12-08 |
Kode Biotech Limited |
Synthetic molecule constructs
|
EP1730280B1
(de)
*
|
2004-03-26 |
2018-10-24 |
Curis, Inc. |
Rna-interferenz modulator des hedgehog-signaltransduktionsweges und deren verwendungen
|
WO2006073419A2
(en)
*
|
2004-04-01 |
2006-07-13 |
Gang Zheng |
Lipoprotein nanoplatforms
|
US20050244869A1
(en)
*
|
2004-04-05 |
2005-11-03 |
Brown-Driver Vickie L |
Modulation of transthyretin expression
|
EP1750776A2
(de)
*
|
2004-04-30 |
2007-02-14 |
Alnylam Pharmaceuticals Inc. |
Oligonukleotide mit c5-modifiziertem pyrimidin
|
DE102004024617A1
(de)
|
2004-05-18 |
2005-12-29 |
Ganymed Pharmaceuticals Ag |
Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
|
US10508277B2
(en)
|
2004-05-24 |
2019-12-17 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
US20050287667A1
(en)
|
2004-06-01 |
2005-12-29 |
Pronai Therapeutics, Inc. |
Methods and compositions for the inhibition of gene expression
|
US20050272100A1
(en)
*
|
2004-06-02 |
2005-12-08 |
Arthur Karlin |
Separation and quantification of biotinylated macromolecules
|
US8394947B2
(en)
|
2004-06-03 |
2013-03-12 |
Isis Pharmaceuticals, Inc. |
Positionally modified siRNA constructs
|
US20090048192A1
(en)
*
|
2004-06-03 |
2009-02-19 |
Isis Pharmaceuticals, Inc. |
Double Strand Compositions Comprising Differentially Modified Strands for Use in Gene Modulation
|
EP1765415A4
(de)
*
|
2004-06-03 |
2010-03-24 |
Isis Pharmaceuticals Inc |
Oligomere verbindungen zur erleichterung der risc-beladung
|
LT2662390T
(lt)
|
2004-06-21 |
2017-10-10 |
E. R. Squibb & Sons, L.L.C. |
Interferono-alfa receptoriaus-1 antikūnai ir jų panaudojimas
|
CA2571243A1
(en)
|
2004-06-21 |
2006-01-05 |
The Board Of Trustees Of The Leland Stanford Junior University |
Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder
|
US8288557B2
(en)
|
2004-07-23 |
2012-10-16 |
Endocyte, Inc. |
Bivalent linkers and conjugates thereof
|
US7884086B2
(en)
|
2004-09-08 |
2011-02-08 |
Isis Pharmaceuticals, Inc. |
Conjugates for use in hepatocyte free uptake assays
|
JP5101288B2
(ja)
*
|
2004-10-05 |
2012-12-19 |
カリフォルニア インスティテュート オブ テクノロジー |
アプタマー調節される核酸及びその利用
|
AU2005304112B2
(en)
*
|
2004-11-09 |
2009-06-04 |
Roche Innovation Center Copenhagen A/S |
Potent LNA oligonucleotides for the inhibition of HIF-1a expression
|
US9447138B2
(en)
|
2004-11-09 |
2016-09-20 |
Roche Innovation Center Copenhagen A/S |
Potent LNA oligonucleotides for the inhibition of HIF-1a expression
|
MX2007005557A
(es)
*
|
2004-11-09 |
2008-02-15 |
Santaris Pharma As |
Oligonucleotidos lna y el tratamiento de cancer.
|
US20080207522A1
(en)
|
2004-11-12 |
2008-08-28 |
Hancock Robert E W |
Antimicrobial Peptides
|
BRPI0517790A
(pt)
*
|
2004-11-12 |
2008-10-21 |
Neurochem Int Ltd |
métodos e composições fluoradas para tratar doenças relacionadas à amilóide
|
US20060167057A1
(en)
*
|
2004-11-16 |
2006-07-27 |
Xianqi Kong |
Compounds for the treatment of CNS and amyloid associated diseases
|
US8044100B2
(en)
*
|
2004-12-22 |
2011-10-25 |
Bellus Health Inc. |
Methods and compositions for treating amyloid-related diseases
|
CA2592302C
(en)
*
|
2004-12-23 |
2013-10-29 |
Purdue Research Foundation |
Positron emission tomography imaging method
|
AU2006213686A1
(en)
|
2005-02-09 |
2006-08-17 |
Avi Bio Pharma, Inc. |
Antisense composition and method for treating muscle atrophy
|
CA2597325A1
(en)
|
2005-03-10 |
2006-09-21 |
Genentech, Inc. |
Methods and compositions for modulating vascular integrity
|
US8044200B2
(en)
*
|
2005-03-16 |
2011-10-25 |
Endocyte, Inc. |
Synthesis and purification of pteroic acid and conjugates thereof
|
ES2716874T3
(es)
|
2005-03-23 |
2019-06-17 |
Genmab As |
Anticuerpos contra cd38 para el tratamiento del mieloma múltiple
|
ES2381201T3
(es)
|
2005-03-31 |
2012-05-24 |
Calando Pharmaceuticals, Inc. |
Inhibidores de la subunidad 2 de la ribonucleótido-reductasa y utilizaciones de los mismos
|
EP2172487A1
(de)
|
2005-04-22 |
2010-04-07 |
Morphotek Inc. |
Antikörper mit Immuneffektoraktivität, die in Folatrezeptor alpha-positive Zellen internalisiert werden
|
EP3530736A3
(de)
|
2005-05-09 |
2019-11-06 |
ONO Pharmaceutical Co., Ltd. |
Humane monoklonale antikörper für den programmierten tod 1 (pd-1) und verfahren zur behandlung von krebs mit pd-1-antikörpern allein oder in kombination mit anderen immunotherapeutika
|
US8097703B2
(en)
|
2005-06-20 |
2012-01-17 |
Medarex, Inc. |
CD19 antibodies and their uses
|
SI1907424T1
(sl)
|
2005-07-01 |
2015-12-31 |
E. R. Squibb & Sons, L.L.C. |
Humana monoklonska protitelesa proti programiranem smrtnem ligandu 1 (PD-L1)
|
JP5175723B2
(ja)
|
2005-07-05 |
2013-04-03 |
パーデュー・リサーチ・ファウンデーション |
単球介在性疾患を治療するための組成物の調製
|
US20090176725A1
(en)
*
|
2005-08-17 |
2009-07-09 |
Sirna Therapeutics Inc. |
Chemically modified short interfering nucleic acid molecules that mediate rna interference
|
KR101364912B1
(ko)
*
|
2005-08-19 |
2014-02-21 |
엔도사이트, 인코포레이티드 |
복수-약제 리간드 공액체
|
WO2007022493A2
(en)
*
|
2005-08-19 |
2007-02-22 |
Endocyte, Inc. |
Ligand conjugates of vinca alkaloids, analogs, and derivatives
|
US8507439B2
(en)
|
2005-08-29 |
2013-08-13 |
Angela Shashoua |
Neuroprotective and neurorestorative method and compositions
|
EP1762575A1
(de)
|
2005-09-12 |
2007-03-14 |
Ganymed Pharmaceuticals AG |
Identifizierung Tumor-assoziierter Antigene für Diagnoseund Therapie
|
KR20080068019A
(ko)
*
|
2005-09-15 |
2008-07-22 |
산타리스 팔마 에이/에스 |
아포지단백질-b100 발현 억제용 rna 길항제 화합물
|
EP1940473A2
(de)
*
|
2005-09-23 |
2008-07-09 |
Purdue Research Foundation |
Verfahren und vorrichtung für die multiphotonen-in-vivo-durchflusszytometrie
|
EA016186B1
(ru)
|
2005-09-26 |
2012-03-30 |
Медарекс, Инк. |
Человеческие моноклональные антитела к cd70 и их применение
|
JP5006330B2
(ja)
|
2005-10-21 |
2012-08-22 |
ノバルティス アーゲー |
Il13に対するヒト抗体および治療的使用
|
US20070099246A1
(en)
*
|
2005-11-03 |
2007-05-03 |
Sandy John D |
Antibodies, assays and kits to quantitate cartilage destruction
|
EP2564864B8
(de)
|
2005-11-12 |
2015-05-13 |
The Board of Trustees of The Leland Stanford Junior University |
Verfahren im Zusammenhang mit FGF2 zur Diagnose und Behandlung von Depressionen
|
US7807652B2
(en)
|
2005-11-21 |
2010-10-05 |
Isis Pharmaceuticals, Inc. |
Modulation of eIF4E-BP2 expression
|
EP1790664A1
(de)
|
2005-11-24 |
2007-05-30 |
Ganymed Pharmaceuticals AG |
Monoklonale Antikörper gegen Claudin-18 zur Behandlung von Krebs
|
EP3000480A1
(de)
|
2005-12-01 |
2016-03-30 |
ProNAi Therapeutics, Inc. |
Krebstherapien und dabei verwendete pharmazeutische zusammensetzungen
|
JP5512128B2
(ja)
|
2005-12-08 |
2014-06-04 |
メダレックス・リミテッド・ライアビリティ・カンパニー |
フコシルgm1に対するヒトモノクローナル抗体および抗フコシルgm1を使用するための方法
|
IL173104A0
(en)
|
2006-01-12 |
2006-06-11 |
Yeda Res & Dev |
Siva and ubiquintination
|
EP1976883B1
(de)
|
2006-01-17 |
2012-10-03 |
Medarex, Inc. |
Monoklonale antikörper gegen cd30 ohne fucosyl- und xylosylreste
|
WO2007089584A2
(en)
|
2006-01-26 |
2007-08-09 |
Isis Pharmaceuticals, Inc. |
Compositions and their uses directed to huntingtin
|
WO2007092299A2
(en)
*
|
2006-02-03 |
2007-08-16 |
Purdue Research Foundation |
Targeted conjugates and radiation
|
GB0603683D0
(en)
|
2006-02-23 |
2006-04-05 |
Novartis Ag |
Organic compounds
|
US20070232556A1
(en)
*
|
2006-03-31 |
2007-10-04 |
Montine Thomas J |
Methods and compositions for the treatment of neurological diseases and disorders
|
EP2007428A2
(de)
|
2006-04-05 |
2008-12-31 |
Genentech, Inc. |
Verfahren zur verwendung von boc/cdo zur modulation der hedgehog-signalisierung
|
US8758723B2
(en)
|
2006-04-19 |
2014-06-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for cellular imaging and therapy
|
ATE554104T1
(de)
|
2006-04-21 |
2012-05-15 |
Amgen Inc |
Domänen der konstanten region von immunoglobulinen mit verbesserter stabilität
|
EP2021030A2
(de)
*
|
2006-04-21 |
2009-02-11 |
Amgen, Inc. |
Puffermittel für biopharmazeutische formulierungen
|
US20070258941A1
(en)
*
|
2006-05-02 |
2007-11-08 |
Pfister Brian E |
Methods and compositions for remediation of disc herniation by modifying structure
|
EP2013344B1
(de)
*
|
2006-05-03 |
2012-08-29 |
Baltic Technology Development, Ltd. |
Antisense-agentien mit kombination von mit stark gebundener base modifiziertem oligonukleotid und künstlicher nuklease
|
WO2007131034A1
(en)
*
|
2006-05-03 |
2007-11-15 |
The Regents Of The University Of Michigan |
Pyrimidone derivatives which are modulators of heat shock protein (hsp) 70
|
EP2023938A4
(de)
*
|
2006-05-23 |
2010-11-10 |
Isis Pharmaceuticals Inc |
Modulation von chrebp-expression
|
US20100226967A1
(en)
*
|
2006-05-23 |
2010-09-09 |
Purdue Research Foundation |
Imaging and therapeutic method using progenitor cells
|
PE20080102A1
(es)
*
|
2006-05-25 |
2008-02-11 |
Bristol Myers Squibb Co |
Conjugados de analogos de aziridinil-epotilona y composiciones farmaceuticas que comprenden los mismos
|
PE20080316A1
(es)
|
2006-05-25 |
2008-04-10 |
Bristol Myers Squibb Co |
Compuestos de aziridinil-epotilona
|
ES2286951B1
(es)
*
|
2006-05-26 |
2008-10-01 |
Instituto Cientifico Y Tecnologico De Navarra, S.A |
Nanoparticulas bioadhesivas para la administracion de moleculas biologicamente activas.
|
ATE544468T1
(de)
|
2006-06-28 |
2012-02-15 |
Yeda Res & Dev |
Caspase-8 und wundheilung
|
US8198253B2
(en)
|
2006-07-19 |
2012-06-12 |
Isis Pharmaceuticals, Inc. |
Compositions and their uses directed to HBXIP
|
WO2008019394A2
(en)
*
|
2006-08-11 |
2008-02-14 |
The Government Of The United States Of America As Represented By The Secretary, Dept Of Health And Human Services |
Methods for treatment and diagnosis of psychiatric disorders
|
BRPI0714893A2
(pt)
|
2006-09-05 |
2013-05-28 |
Medarex Inc |
anticorpo monoclonal isolado ou uma porÇço de ligaÇço ao seu antÍgeno, um fragmento de anticorpo, um anticorpo mimÉtico, imunoconjugado, composiÇço molÉcula de Ácido nuclÉico isolada, vetor de expressço, cÉlula hospedeira, mÉtodo para preparar um anticorpo anti-bmp2 ou anti-bmp4, mÉtodo para tratar ou prevenir uma doenÇa associada com formaÇço àssea normal e ossificaÇço, hibridoma e metodo para preparar o anticorpo
|
ES2625798T3
(es)
|
2006-10-02 |
2017-07-20 |
E. R. Squibb & Sons, L.L.C. |
Anticuerpos humanos que se unen a CXCR4 y usos de los mismos
|
US10925977B2
(en)
*
|
2006-10-05 |
2021-02-23 |
Ceil>Point, LLC |
Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
|
WO2008045373A2
(en)
*
|
2006-10-06 |
2008-04-17 |
Amgen Inc. |
Stable antibody formulations
|
FI3851447T3
(fi)
|
2006-10-12 |
2023-11-15 |
Bellus Health Inc |
Menetelmiä, yhdisteitä, koostumuksia ja vehikkeleitä 3-amino-1-propaanisulfonihapon vapauttamiseksi
|
EP2094247B1
(de)
*
|
2006-10-20 |
2022-06-29 |
Amgen Inc. |
Stabile polypeptid-formulierungen
|
US8618248B2
(en)
|
2006-10-31 |
2013-12-31 |
President And Fellows Of Harvard College |
Phosphopeptide compositions and anti-phosphopeptide antibody compositions and methods of detecting phosphorylated peptides
|
EP2087337A4
(de)
*
|
2006-11-03 |
2010-09-08 |
Purdue Research Foundation |
Verfahren und vorrichtung für ex-vivo-durchflusszytometrie
|
US8158595B2
(en)
*
|
2006-11-09 |
2012-04-17 |
California Institute Of Technology |
Modular aptamer-regulated ribozymes
|
AU2007334264A1
(en)
|
2006-11-15 |
2008-06-26 |
Medarex, Inc. |
Human monoclonal antibodies to BTLA and methods of use
|
CN101626782B
(zh)
|
2006-12-01 |
2013-03-27 |
梅达雷克斯公司 |
结合cd22的人抗体及其用途
|
CL2007003622A1
(es)
|
2006-12-13 |
2009-08-07 |
Medarex Inc |
Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales.
|
AU2007333098A1
(en)
|
2006-12-14 |
2008-06-19 |
Medarex, Inc. |
Human antibodies that bind CD70 and uses thereof
|
US8048998B2
(en)
*
|
2007-01-19 |
2011-11-01 |
Exiqon A/S |
Mediated cellular delivery of LNA oligonucleotides
|
JP2010516625A
(ja)
|
2007-01-24 |
2010-05-20 |
インサート セラピューティクス, インコーポレイテッド |
制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート
|
EP2114981B1
(de)
|
2007-01-29 |
2013-05-08 |
Isis Pharmaceuticals, Inc. |
Verbindungen und Methoden zur Modulation der Proteinexpression
|
AU2008213702B2
(en)
*
|
2007-02-07 |
2014-04-24 |
Purdue Research Foundation |
Positron emission tomography imaging method
|
US20100104626A1
(en)
*
|
2007-02-16 |
2010-04-29 |
Endocyte, Inc. |
Methods and compositions for treating and diagnosing kidney disease
|
EP3248617A3
(de)
|
2007-02-16 |
2018-02-21 |
Merrimack Pharmaceuticals, Inc. |
Antikörper gegen erbb3 und verwendungen davon
|
WO2008103962A2
(en)
|
2007-02-22 |
2008-08-28 |
Genentech, Inc. |
Methods for detecting inflammatory bowel disease
|
EP1970384A1
(de)
*
|
2007-03-14 |
2008-09-17 |
Ganymed Pharmaceuticals AG |
Monoklonale Antikörper zur Krebsbehandlung
|
NZ580132A
(en)
*
|
2007-03-14 |
2012-11-30 |
Endocyte Inc |
Binding ligand linked drug delivery conjugates of tubulysins to vitamins
|
CA2681661C
(en)
|
2007-03-23 |
2015-11-24 |
New York University |
Methods of increasing nitrogen-assimilation capacity in transgenic plants expressing cca1 and glk1
|
JP5779350B2
(ja)
|
2007-03-27 |
2015-09-16 |
シー レーン バイオテクノロジーズ, エルエルシー |
抗体代替軽鎖配列を含む構築物およびライブラリー
|
GB2463584B
(en)
|
2007-04-27 |
2012-02-01 |
Kode Biotech Ltd |
Carbohydrate-lipid constructs and their use in preventing or treating viral infection
|
GB0709835D0
(en)
|
2007-05-22 |
2007-07-04 |
Plant Bioscience Ltd |
Composition and method for modulating plant root hair development
|
AU2008257419B2
(en)
|
2007-05-23 |
2013-10-24 |
The Trustees Of The University Of Pennsylvania |
Targeted carriers for intracellular drug delivery
|
US8961926B2
(en)
*
|
2007-05-25 |
2015-02-24 |
Purdue Research Foundation |
Method of imaging localized infections
|
JP2010528115A
(ja)
|
2007-05-25 |
2010-08-19 |
ブリストル−マイヤーズ スクイブ カンパニー |
エポチロン化合物およびアナログの製造方法
|
EP1997832A1
(de)
|
2007-05-29 |
2008-12-03 |
Ganymed Pharmaceuticals AG |
Monoklonale Antikörper gegen Claudin-18 zur Behandlung von Krebs
|
US9877965B2
(en)
|
2007-06-25 |
2018-01-30 |
Endocyte, Inc. |
Vitamin receptor drug delivery conjugates for treating inflammation
|
AU2008268432B2
(en)
*
|
2007-06-25 |
2015-01-15 |
Endocyte, Inc. |
Conjugates containing hydrophilic spacer linkers
|
US20090082217A1
(en)
*
|
2007-07-16 |
2009-03-26 |
California Institute Of Technology |
Selection of nucleic acid-based sensor domains within nucleic acid switch platform
|
WO2009018386A1
(en)
|
2007-07-31 |
2009-02-05 |
Medimmune, Llc |
Multispecific epitope binding proteins and uses thereof
|
EP2185692A4
(de)
|
2007-08-10 |
2012-05-02 |
Medarex Inc |
Hco32 und hco27 sowie entsprechende beispiele
|
US8367815B2
(en)
*
|
2007-08-28 |
2013-02-05 |
California Institute Of Technology |
Modular polynucleotides for ligand-controlled regulatory systems
|
US20120165387A1
(en)
|
2007-08-28 |
2012-06-28 |
Smolke Christina D |
General composition framework for ligand-controlled RNA regulatory systems
|
US8394391B2
(en)
*
|
2007-08-31 |
2013-03-12 |
University Of Utah Research Foundation |
Drug delivery vehicle that mimics viral properties
|
PL2769729T3
(pl)
|
2007-09-04 |
2019-09-30 |
Compugen Ltd. |
Polipeptydy i polinukleotydy i ich zastosowanie jako cel dla leków do wytwarzania leków i środków biologicznych
|
US8865667B2
(en)
*
|
2007-09-12 |
2014-10-21 |
California Institute Of Technology |
Higher-order cellular information processing devices
|
AU2008307482B2
(en)
|
2007-10-02 |
2012-07-12 |
Amgen Inc. |
Increasing erythropoietin using nucleic acids hybridizable to micro-RNA and precursors thereof
|
AR068767A1
(es)
|
2007-10-12 |
2009-12-02 |
Novartis Ag |
Anticuerpos contra esclerostina, composiciones y metodos de uso de estos anticuerpos para tratar un trastorno patologico mediado por esclerostina
|
EP2209374B1
(de)
|
2007-10-25 |
2014-12-03 |
Endocyte, Inc. |
Tubulysine und verfahren zu ihrer herstellung
|
EA201000718A1
(ru)
|
2007-11-02 |
2011-06-30 |
Новартис Аг |
Молекулы и способы, предназначенные для модуляции родственного рецептору липопротеидов низкой плотности белка 6 (lrp6)
|
EP2217705A2
(de)
*
|
2007-11-05 |
2010-08-18 |
Baltic Technology Development, Ltd. |
Verwendung von oligonukleotiden mit modifizierten basen bei der hybridisierung von nukleinsäuren
|
ES2445755T3
(es)
|
2007-11-07 |
2014-03-05 |
Celldex Therapeutics, Inc. |
Anticuerpos que se unen a células dendríticas y epiteliales humanas 205 (DEC-205)
|
EP2222328A4
(de)
*
|
2007-11-15 |
2013-06-05 |
Endocyte Inc |
Verfahren zur verabreichung von konjugaten
|
BRPI0819063A2
(pt)
|
2007-11-27 |
2020-08-18 |
The University Of British Columbia |
método para tratamento de artrite, anticorpo, hibridoma, antagonista de 14-3-3, usos de um antagonista de 14-3-3, composições farmacêuticas, método para redução da expressão de mmp no sinóvio de um paciente e usos de uma composição farmacêutica
|
US8507455B2
(en)
|
2007-12-04 |
2013-08-13 |
Alnylam Pharmaceuticals, Inc. |
Folate conjugates
|
CA2910760C
(en)
|
2007-12-04 |
2019-07-09 |
Muthiah Manoharan |
Targeting lipids
|
US9029524B2
(en)
*
|
2007-12-10 |
2015-05-12 |
California Institute Of Technology |
Signal activated RNA interference
|
ES2613963T3
(es)
|
2008-01-18 |
2017-05-29 |
Medimmune, Llc |
Anticuerpos manipulados con cisteína para conjugación específica de sitio
|
EP2641612A1
(de)
|
2008-02-05 |
2013-09-25 |
Bristol-Myers Squibb Company |
Alpha-5-Beta-1-Antikörper und ihre Verwendungen
|
SI2250279T1
(sl)
|
2008-02-08 |
2016-10-28 |
Medimmune, Llc |
Protitelesa anti-IFNAR1 z zmanjšano afiniteto do FC liganda
|
US8470772B2
(en)
|
2008-02-27 |
2013-06-25 |
Temple University—Of the Commonwealth System of Higher Education |
Leptin agonist and methods of use
|
AU2009223838B2
(en)
|
2008-03-03 |
2012-07-26 |
The University Of Miami |
Allogeneic cancer cell-based immunotherapy
|
CA2718884C
(en)
|
2008-03-20 |
2016-11-22 |
University Of Miami |
Heat shock protein gp96 vaccination and methods of using same
|
AU2009232355A1
(en)
|
2008-04-04 |
2009-10-08 |
Calando Pharmaceuticals, Inc. |
Compositions and use of EPAS1 inhibitors
|
JP5788312B2
(ja)
|
2008-04-11 |
2015-09-30 |
アルニラム ファーマスーティカルズ インコーポレイテッドAlnylam Pharmaceuticals, Inc. |
標的リガンドをエンドソーム分解性成分と組み合わせることによる核酸の部位特異的送達
|
US10485879B2
(en)
|
2008-04-15 |
2019-11-26 |
Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health |
Plasma cell cytokine vehicle containing fusion proteins for targeted introduction of siRNA into cells and tissues
|
AU2009236270B2
(en)
|
2008-04-15 |
2014-06-26 |
Government Of The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Compositions and methods for delivering inhibitory oligonucleotides
|
PT2274331E
(pt)
|
2008-05-02 |
2014-02-27 |
Novartis Ag |
Moléculas de ligação baseadas em fibronectina melhoradas e suas utilizações
|
JP5735417B2
(ja)
|
2008-05-30 |
2015-06-17 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
減数分裂期キネシンに関連する疾患を治療する方法
|
WO2010008582A2
(en)
|
2008-07-18 |
2010-01-21 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell drug delivery system
|
EP2323667A4
(de)
*
|
2008-08-07 |
2012-07-25 |
Isis Pharmaceuticals Inc |
Modulierung der transthyretin-expression durch behandlung von zns-erkrankungen
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
NZ591416A
(en)
|
2008-08-25 |
2012-11-30 |
Excaliard Pharmaceuticals Inc |
Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
|
EP2166021A1
(de)
*
|
2008-09-16 |
2010-03-24 |
Ganymed Pharmaceuticals AG |
Monoklonale Antikörper zur Krebsbehandlung
|
EP2949752B1
(de)
|
2008-09-22 |
2017-12-20 |
RXi Pharmaceuticals Corporation |
Selbstfreisetzende rnai-verbindungen von reduzierter grösse
|
DK2342226T3
(en)
|
2008-09-26 |
2016-09-26 |
Dana Farber Cancer Inst Inc |
HUMAN ANTI-PD-1, PD-L1 AND PD-L2 ANTIBODIES AND APPLICATIONS THEREOF
|
CA2736729A1
(en)
|
2008-09-29 |
2010-04-01 |
Ben Gurion University Of The Negev Research And Development Authority |
Amyloid beta-peptides and methods of use thereof
|
GB2465748B
(en)
|
2008-11-25 |
2012-04-25 |
Algentech Sas |
Plant cell transformation method
|
GB2465749B
(en)
|
2008-11-25 |
2013-05-08 |
Algentech Sas |
Plant cell transformation method
|
ES2629630T3
(es)
|
2008-12-04 |
2017-08-11 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con eritropoyetina (EPO) mediante inhibición del transcrito antisentido natural a EPO
|
MX2011005918A
(es)
|
2008-12-04 |
2011-06-17 |
Opko Curna Llc |
Tratamiento de enfermedades relacionadas con un gen supresor de tumor mediante inhibicion del transcrito antisentido natural para el gen.
|
WO2010065662A2
(en)
|
2008-12-04 |
2010-06-10 |
Curna, Inc. |
Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirtuin 1
|
EP2865689A1
(de)
|
2008-12-08 |
2015-04-29 |
Compugen Ltd. |
FAM26F Polypeptide und Polynukleotide und Verwendungen davon als Arzneimittel-Target zur Herstellung von Arzneimitteln und Biologika
|
WO2010078536A1
(en)
|
2009-01-05 |
2010-07-08 |
Rxi Pharmaceuticals Corporation |
Inhibition of pcsk9 through rnai
|
GB2467167B
(en)
|
2009-01-26 |
2013-09-11 |
Algentech Sas |
Gene targeting in plants
|
WO2010090762A1
(en)
|
2009-02-04 |
2010-08-12 |
Rxi Pharmaceuticals Corporation |
Rna duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
|
CA2752237C
(en)
|
2009-02-12 |
2020-03-24 |
Opko Curna, Llc |
Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf
|
JP6066035B2
(ja)
|
2009-02-12 |
2017-01-25 |
クルナ・インコーポレーテッド |
グリア細胞由来神経栄養因子(gdnf)関連疾病の、gdnfに対する天然アンチセンス転写物の抑制による治療
|
US8329882B2
(en)
|
2009-02-18 |
2012-12-11 |
California Institute Of Technology |
Genetic control of mammalian cells with synthetic RNA regulatory systems
|
ES2845644T3
(es)
|
2009-03-04 |
2021-07-27 |
Curna Inc |
Tratamiento de enfermedades relacionadas con sirtuina1 (SIRT1) mediante inhibición del transcrito del antisentido natural a sirtuina 1
|
EA028336B1
(ru)
|
2009-03-05 |
2017-11-30 |
МЕДАРЕКС Л.Л.Си. |
Полностью человеческие антитела, специфические в отношении cadm1
|
CA2755409C
(en)
|
2009-03-16 |
2019-04-30 |
Joseph Collard |
Treatment of nuclear factor (erythroid-derived 2)-like 2 (nrf2) related diseases by inhibition of natural antisense transcript to nrf2
|
CA2755404C
(en)
|
2009-03-17 |
2020-03-24 |
Joseph Collard |
Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1
|
CN102356155B
(zh)
|
2009-03-18 |
2016-02-24 |
肿瘤疗法科学股份有限公司 |
Neil3肽及包含它的疫苗
|
US9145555B2
(en)
|
2009-04-02 |
2015-09-29 |
California Institute Of Technology |
Integrated—ligand-responsive microRNAs
|
CA2759538C
(en)
|
2009-04-20 |
2018-07-24 |
Oxford Biotherapeutics Ltd |
Antibodies specific to cadherin-17
|
EP3248618A1
(de)
|
2009-04-22 |
2017-11-29 |
Massachusetts Institute Of Technology |
Angeborene immununterdrückung mit ermöglichung der wiederholten verabreichung von langen rna-molekülen
|
MA33279B1
(fr)
|
2009-04-27 |
2012-05-02 |
Novartis Ag |
Compositions et procédés pour l'augmentation de la croissance des muscles
|
EA201101572A1
(ru)
|
2009-04-27 |
2012-05-30 |
Новартис Аг |
Композиции и способы применения терапевтических антител, специфичных в отношении субъединицы бета1 рецептора il-12
|
NO2424987T3
(de)
|
2009-05-01 |
2018-04-14 |
|
|
PL2448970T3
(pl)
|
2009-05-04 |
2014-12-31 |
Abbvie Res B V |
Przeciwciało przeciwko czynnikowi wzrostu nerwów (NGF) ze zwiększoną stabilnością in vivo
|
CA2761142C
(en)
|
2009-05-06 |
2021-06-08 |
Opko Curna, Llc |
Treatment of tristetraproline (ttp) related diseases by inhibition of natural antisense transcript to ttp
|
CN103223177B
(zh)
|
2009-05-06 |
2016-08-10 |
库尔纳公司 |
通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病
|
CN102482345A
(zh)
|
2009-05-13 |
2012-05-30 |
航道生物技术有限责任公司 |
针对流感病毒的中和分子
|
CN102575251B
(zh)
|
2009-05-18 |
2018-12-04 |
库尔纳公司 |
通过抑制针对重编程因子的天然反义转录物来治疗重编程因子相关的疾病
|
US20120128673A1
(en)
|
2009-05-20 |
2012-05-24 |
Schering Corporation |
Modulation of pilr receptors to treat microbial infections
|
US8895527B2
(en)
|
2009-05-22 |
2014-11-25 |
Curna, Inc. |
Treatment of transcription factor E3 (TFE3) and insulin receptor substrate 2(IRS2) related diseases by inhibition of natural antisense transcript to TFE3
|
TWI507204B
(zh)
|
2009-05-26 |
2015-11-11 |
Oncotherapy Science Inc |
Cdc45l胜肽與含此胜肽之疫苗
|
CA2764683A1
(en)
|
2009-05-28 |
2010-12-02 |
Joseph Collard |
Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene
|
EP2443241A1
(de)
|
2009-06-15 |
2012-04-25 |
Plant Bioscience Limited |
Herstellung von viralen kapsiden
|
JP6128846B2
(ja)
|
2009-06-16 |
2017-05-17 |
クルナ・インコーポレーテッド |
パラオキソナーゼ(pon1)に対する天然アンチセンス転写物の抑制によるpon1遺伝子関連疾患の治療
|
ES2620960T3
(es)
|
2009-06-16 |
2017-06-30 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con un gen de colágeno mediante la inhibición de un transcrito antisentido natural a un gen de colágeno
|
AU2010270979B2
(en)
|
2009-06-22 |
2015-04-23 |
Medimmune, Llc |
Engineered Fc regions for site-specific conjugation
|
JP6073133B2
(ja)
|
2009-06-24 |
2017-02-01 |
クルナ・インコーポレーテッド |
腫瘍壊死因子受容体2(tnfr2)に対する天然アンチセンス転写物の抑制によるtnfr2関連疾患の治療
|
WO2010151674A2
(en)
|
2009-06-26 |
2010-12-29 |
Curna, Inc. |
Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene
|
US8394922B2
(en)
|
2009-08-03 |
2013-03-12 |
Medarex, Inc. |
Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof
|
KR101802536B1
(ko)
|
2009-08-05 |
2017-11-28 |
큐알엔에이, 인크. |
인슐린 유전자 (ins)에 대한 자연 안티센스 전사체의 저해에 의한 인슐린 유전자 (ins) 관련된 질환의 치료
|
US20120131701A1
(en)
|
2009-08-05 |
2012-05-24 |
Chromocell Corporation |
Improved plants, microbes, and organisms
|
JP5964232B2
(ja)
|
2009-08-25 |
2016-08-03 |
カッパーアールエヌエー,インコーポレイテッド |
‘iqモチーフ含有gtpアーゼ活性化タンパク質’(iqgap)に対する天然アンチセンス転写産物の阻害によるiqgap関連疾患の治療
|
US20110059111A1
(en)
|
2009-09-01 |
2011-03-10 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Mammalian receptors as targets for antibody and active vaccination therapy against mold infections
|
DK2473522T3
(en)
|
2009-09-02 |
2016-11-28 |
Genentech Inc |
Smoothened MUTANT AND METHODS OF USING THE SAME
|
WO2011029823A1
(en)
|
2009-09-09 |
2011-03-17 |
Novartis Ag |
Monoclonal antibody reactive with cd63 when expressed at the surface of degranulated mast cells
|
EP4089169A1
(de)
|
2009-10-12 |
2022-11-16 |
Larry J. Smith |
Verfahren und zusammensetzungen zum modulieren der genexpression mit in-vivo oder in-vitro verabreichten arzneistoffen auf oligonukleotidbasis
|
US20120231004A1
(en)
|
2009-10-13 |
2012-09-13 |
Oxford Biotherapeutic Ltd. |
Antibodies
|
RU2539772C2
(ru)
|
2009-10-22 |
2015-01-27 |
Дженентек, Инк. |
Способы и композиции для модуляции гепсином стимулирующего макрофаги белка
|
EP2357239A1
(de)
|
2009-10-29 |
2011-08-17 |
Universität zu Köln |
Verfahren und Mittel für ein auswählbares Markierungssystem bei Pflanzen
|
WO2011051327A2
(en)
|
2009-10-30 |
2011-05-05 |
Novartis Ag |
Small antibody-like single chain proteins
|
WO2011051466A1
(en)
|
2009-11-02 |
2011-05-05 |
Novartis Ag |
Anti-idiotypic fibronectin-based binding molecules and uses thereof
|
US20120244169A1
(en)
|
2009-11-06 |
2012-09-27 |
Fibrogen, Inc. |
Treatment for Radiation-Induced Disorders
|
CN102781237A
(zh)
*
|
2009-11-23 |
2012-11-14 |
天蓝制药公司 |
用于传递治疗剂的基于环糊精的聚合物
|
MX2012006072A
(es)
|
2009-11-30 |
2012-07-23 |
Genentech Inc |
Composiciones y metodos para el diagnostico y el tratamiento de tumores.
|
US9428586B2
(en)
|
2009-12-01 |
2016-08-30 |
Compugen Ltd |
Heparanase splice variant
|
EP2509953B1
(de)
|
2009-12-11 |
2016-03-30 |
Genecode AS |
Verfahren für das überleben von nervenzellen mit ligandenmimetika der gdnf-familie oder aktivatoren des ret-signalweges
|
TW201136604A
(en)
|
2009-12-14 |
2011-11-01 |
Oncotherapy Science Inc |
TMEM22 peptides and vaccines including the same
|
DK2513310T3
(en)
|
2009-12-16 |
2018-02-05 |
Curna Inc |
TREATMENT OF DISEASES CONNECTED WITH MEMBRANE-BONDED TRANSCRIPTION FACTOR Peptidase, site 1 (MBTPS1), BY INHIBITION OF NATURAL ANTISENCE TRANSCRIPTION TO MBTPS1
|
US8691227B2
(en)
|
2009-12-17 |
2014-04-08 |
Merck Sharp & Dohme Corp. |
Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
|
EP3000885B1
(de)
|
2009-12-18 |
2018-07-25 |
Arrowhead Pharmaceuticals, Inc. |
Organische zusammensetzungen zur behandlung von hsf1-bedingten erkrankungen
|
EP2515947B1
(de)
|
2009-12-23 |
2021-10-06 |
CuRNA, Inc. |
Behandlung von durch das uncoupling protein 2 (ucp2) bedingten erkrankungen mittels hemmung des natürlichen antisense-transkripts für ucp2
|
DK2516648T3
(en)
|
2009-12-23 |
2018-02-12 |
Curna Inc |
TREATMENT OF HEPATOCYTE GROWTH FACTOR (HGF) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT AGAINST HGF
|
JP5993744B2
(ja)
|
2009-12-29 |
2016-09-14 |
カッパーアールエヌエー,インコーポレイテッド |
核呼吸因子1(nrf1)に対する天然アンチセンス転写物の阻害による核呼吸因子1関連疾患の治療
|
EP2519634B1
(de)
|
2009-12-29 |
2016-06-01 |
CuRNA, Inc. |
Behandlung von durch das tumorprotein 63 (p63) vermittelten erkrankungen durch das natürliche antisense-transkript für p63
|
EP2521784B1
(de)
|
2010-01-04 |
2017-12-06 |
CuRNA, Inc. |
Behandlung von erkrankungen im zusammenhang mit dem interferonregulierungsfaktor 8 (irf8) mittels hemmung des natürlichen antisense-transkripts gegen irf8
|
EP2521785B1
(de)
|
2010-01-06 |
2022-03-09 |
CuRNA, Inc. |
Inhibition des natürlichen antisense-transkripts des pankreasentwicklungsgens zur verwendung in der behandlung von pankreatischen entwicklungsgenbezogenen krankheiten
|
ES2664866T3
(es)
|
2010-01-11 |
2018-04-23 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con la globulina fijadora de hormonas sexuales (shbg) mediante inhibición del transcrito antisentido natural a shbg
|
WO2011090971A2
(en)
|
2010-01-19 |
2011-07-28 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for male reproductive disorders
|
DK2529015T3
(en)
|
2010-01-25 |
2018-02-26 |
Curna Inc |
TREATMENT OF RNASE H1-RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO RNASE H1
|
WO2011092233A1
(en)
|
2010-01-29 |
2011-08-04 |
Novartis Ag |
Yeast mating to produce high-affinity combinations of fibronectin-based binders
|
WO2011098449A1
(en)
|
2010-02-10 |
2011-08-18 |
Novartis Ag |
Methods and compounds for muscle growth
|
CA2790506A1
(en)
|
2010-02-22 |
2011-08-25 |
Curna, Inc. |
Treatment of pyrroline-5-carboxylate reductase 1 (pycr1) related diseases by inhibition of natural antisense transcript to pycr1
|
AU2011221226A1
(en)
|
2010-02-23 |
2012-08-16 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
KR20220017432A
(ko)
|
2010-02-24 |
2022-02-11 |
이뮤노젠 아이엔씨 |
엽산염 수용체 1 항체와 면역접합체 및 이들의 용도
|
BR112012022641A2
(pt)
|
2010-03-11 |
2017-02-14 |
Oncotherapy Science Inc |
peptídeos hjurp e vacinas que incluem os mesmos
|
JP2013522313A
(ja)
|
2010-03-17 |
2013-06-13 |
アボツト・リサーチ・ベー・フエー |
抗神経成長因子(ngf)抗体組成物
|
EP2371864A1
(de)
|
2010-03-23 |
2011-10-05 |
Ganymed Pharmaceuticals AG |
Monoklonale Antikörper zur Krebsbehandlung
|
RU2615143C2
(ru)
|
2010-03-24 |
2017-04-04 |
Адвирна |
Самодоставляющие PHKi соединения уменьшенного размера
|
CN107098958B
(zh)
|
2010-03-26 |
2021-11-05 |
达特茅斯大学理事会 |
Vista调节性t细胞介体蛋白、vista结合剂及其用途
|
US20150231215A1
(en)
|
2012-06-22 |
2015-08-20 |
Randolph J. Noelle |
VISTA Antagonist and Methods of Use
|
US10745467B2
(en)
|
2010-03-26 |
2020-08-18 |
The Trustees Of Dartmouth College |
VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
|
TWI538685B
(zh)
|
2010-04-02 |
2016-06-21 |
腫瘤療法 科學股份有限公司 |
Ect2胜肽及含此胜肽之疫苗
|
TWI644675B
(zh)
|
2010-04-09 |
2018-12-21 |
可娜公司 |
藉由抑制纖維母細胞生長因子21(fgf21)之天然反義轉錄物以治療fgf21相關疾病
|
EA024701B1
(ru)
|
2010-04-13 |
2016-10-31 |
Селлдекс Терапьютикс Инк. |
Антитела, связывающие cd27 человека, и их применение
|
WO2011130716A2
(en)
|
2010-04-16 |
2011-10-20 |
Access Pharmaceuticals, Inc. |
A nanostructures containing vitamin b12 for facilitated delivery of drugs across biological barriers
|
CN102985544A
(zh)
|
2010-04-23 |
2013-03-20 |
诺瓦提斯公司 |
治疗β-ENaC-相关疾病的有机组合物
|
WO2011139917A1
(en)
|
2010-04-29 |
2011-11-10 |
Isis Pharmaceuticals, Inc. |
Modulation of transthyretin expression
|
CN107090045A
(zh)
|
2010-05-03 |
2017-08-25 |
霍夫曼-拉罗奇有限公司 |
用于肿瘤诊断和治疗的组合物和方法
|
KR20130101442A
(ko)
|
2010-05-03 |
2013-09-13 |
큐알엔에이, 인크. |
시르투인 (sirt)에 대한 자연 안티센스 전사체의 저해에 의한 시르투인 (sirt) 관련된 질환의 치료
|
WO2011140151A1
(en)
|
2010-05-04 |
2011-11-10 |
Dyax Corp. |
Antibodies against epidermal growth factor receptor (egfr)
|
CN102958924B
(zh)
|
2010-05-05 |
2017-06-27 |
伊利诺伊大学评议会 |
治疗脑病症的化合物和方法
|
ES2949159T3
(es)
|
2010-05-06 |
2023-09-26 |
Novartis Ag |
Composiciones y métodos de uso para anticuerpos terapéuticos de proteína 6 relacionada con lipoproteínas de baja densidad (LRP6)
|
KR20130066631A
(ko)
|
2010-05-06 |
2013-06-20 |
노파르티스 아게 |
치료적 저밀도 지단백질-관련 단백질 6 (lrp6) 다가 항체에 대한 조성물 및 사용 방법
|
US9457079B2
(en)
|
2010-05-12 |
2016-10-04 |
The Trustees Of Columbia University In The City Of New York |
Methods for producing enteroendocrine cells that make and secrete insulin
|
TWI531370B
(zh)
|
2010-05-14 |
2016-05-01 |
可娜公司 |
藉由抑制par4天然反股轉錄本治療par4相關疾病
|
GB201008720D0
(en)
|
2010-05-25 |
2010-07-07 |
Univ Aberdeen |
RxLR-leader peptides and protein translocation
|
JP5973996B2
(ja)
|
2010-05-26 |
2016-08-23 |
カッパーアールエヌエー,インコーポレイテッド |
Atoh1に対する天然アンチセンス転写物の阻害による無調ホモログ1(atoh1)関連疾患の治療
|
WO2016030888A1
(en)
|
2014-08-26 |
2016-03-03 |
Compugen Ltd. |
Polypeptides and uses thereof as a drug for treatment of autoimmune disorders
|
EP2588123A2
(de)
|
2010-06-30 |
2013-05-08 |
Compugen Ltd. |
C1orf32 zur behandlung von multipler sklerose, rheumatoider arthritis und anderen autoimmunerkrankungen
|
RU2611190C2
(ru)
|
2010-07-14 |
2017-02-21 |
Курна, Инк. |
Лечение заболеваний, связанных с геном dlg, путем ингибирования природного антисмыслового транскрипта гена dlg
|
GB201012420D0
(en)
|
2010-07-23 |
2010-09-08 |
Univ Erasmus Medical Ct |
Foetal heamoglobin inhibitor
|
WO2012022734A2
(en)
|
2010-08-16 |
2012-02-23 |
Medimmune Limited |
Anti-icam-1 antibodies and methods of use
|
PT2606070T
(pt)
|
2010-08-20 |
2017-03-31 |
Novartis Ag |
Anticorpos para o recetor 3 do fator de crescimento epidérmico (her3)
|
EP2609093B1
(de)
|
2010-08-24 |
2018-10-17 |
SGC Pharma Inc. |
Salzverbindung
|
US8999335B2
(en)
|
2010-09-17 |
2015-04-07 |
Compugen Ltd. |
Compositions and methods for treatment of drug resistant multiple myeloma
|
CN103153332A
(zh)
|
2010-09-28 |
2013-06-12 |
卡尔医疗有限公司 |
用于治疗血液恶性肿瘤的组合物和方法
|
EP3828205A1
(de)
|
2010-10-01 |
2021-06-02 |
Oxford BioTherapeutics Ltd |
Anti-ror1-antikörper
|
CN103154037A
(zh)
|
2010-10-05 |
2013-06-12 |
诺瓦提斯公司 |
抗IL12Rβ1抗体及它们在治疗自身免疫病和炎性疾病中的用途
|
EP2625197B1
(de)
|
2010-10-05 |
2016-06-29 |
Genentech, Inc. |
Smoothened-mutant und verfahren zu seiner anwendung
|
US8993533B2
(en)
|
2010-10-06 |
2015-03-31 |
Curna, Inc. |
Treatment of sialidase 4 (NEU4) related diseases by inhibition of natural antisense transcript to NEU4
|
US9222088B2
(en)
|
2010-10-22 |
2015-12-29 |
Curna, Inc. |
Treatment of alpha-L-iduronidase (IDUA) related diseases by inhibition of natural antisense transcript to IDUA
|
RU2611195C2
(ru)
|
2010-10-27 |
2017-02-21 |
Курна, Инк. |
Лечение заболеваний, связанных с интерферон- связанным регулятором развития 1 (ifrd1), путем ингибирования природного антисмыслового транскрипта к ifrd1
|
US9260471B2
(en)
|
2010-10-29 |
2016-02-16 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)
|
US20140134181A1
(en)
|
2010-11-05 |
2014-05-15 |
Kenneth E. Lipson |
Treatment Method For Lung Remodeling Diseases
|
KR102010598B1
(ko)
|
2010-11-23 |
2019-08-13 |
큐알엔에이, 인크. |
Nanog에 대한 자연 안티센스 전사체의 저해에 의한 nanog 관련된 질환의 치료
|
EP2643353A1
(de)
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispezifische moleküle
|
PL2670411T3
(pl)
|
2011-02-02 |
2019-09-30 |
Excaliard Pharmaceuticals, Inc. |
Związki antysensowne ukierunkowane na czynnik wzrostu tkanki łącznej (ctgf) do leczenia bliznowców lub blizn przerostowych
|
WO2012109495A1
(en)
|
2011-02-09 |
2012-08-16 |
Metabolic Solutions Development Company, Llc |
Cellular targets of thiazolidinediones
|
WO2012119989A2
(en)
|
2011-03-04 |
2012-09-13 |
Oryzon Genomics, S.A. |
Methods and antibodies for the diagnosis and treatment of cancer
|
CN103501821A
(zh)
|
2011-03-08 |
2014-01-08 |
艾克塞斯制药公司 |
用于递送活性剂穿过生物膜的靶向纳米载体系统
|
MX346555B
(es)
|
2011-04-01 |
2017-03-24 |
Immunogen Inc |
Metodos para aumentar la eficacia de la terapia contra el cancer con receptor 1 de folato (folr1).
|
CN103547588B
(zh)
|
2011-04-13 |
2016-06-29 |
Isis制药公司 |
Ptp1b表达的反义调节
|
CN105601741A
(zh)
|
2011-04-15 |
2016-05-25 |
卡姆普根有限公司 |
多肽和多核苷酸及其用于治疗免疫相关失调和癌症的用途
|
CN103620036B
(zh)
|
2011-06-09 |
2016-12-21 |
库尔纳公司 |
通过抑制共济蛋白(fxn)的天然反义转录物而治疗fxn 相关疾病
|
EP2721156B1
(de)
|
2011-06-16 |
2016-12-21 |
Ionis Pharmaceuticals, Inc. |
Antisense-modulierung der expression des fibroblastenwachstumsfaktor-rezeptors 4
|
PT2726508T
(pt)
|
2011-06-28 |
2017-09-26 |
Oxford Biotherapeutics Ltd |
Anticorpos para adp-ribosil ciclase 2
|
AU2012277376B2
(en)
|
2011-06-30 |
2016-11-24 |
Compugen Ltd. |
Polypeptides and uses thereof for treatment of autoimmune disorders and infection
|
HUE040455T2
(hu)
|
2011-06-30 |
2019-03-28 |
Genzyme Corp |
T-sejt aktiválás inhibitorai
|
HUE040276T2
(hu)
|
2011-07-01 |
2019-02-28 |
Novartis Ag |
Eljárás metabolikus rendellenességek kezelésére
|
US9238689B2
(en)
|
2011-07-15 |
2016-01-19 |
Morpho Sys AG |
Antibodies that are cross-reactive for macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT)
|
US9549981B2
(en)
|
2011-07-19 |
2017-01-24 |
Philogen S.P.A. |
Sequential antibody therapy
|
CA2842860A1
(en)
|
2011-07-28 |
2013-01-31 |
Sea Lane Biotechnologies, Llc |
Sur-binding proteins
|
WO2013030778A2
(en)
|
2011-09-02 |
2013-03-07 |
Novartis Ag |
Organic compositions to treat hsf1-related diseases
|
UY34317A
(es)
|
2011-09-12 |
2013-02-28 |
Genzyme Corp |
Anticuerpo antireceptor de célula T (alfa)/ß
|
AU2012312433B2
(en)
|
2011-09-20 |
2017-07-06 |
Ionis Pharmaceuticals, Inc. |
Antisense modulation of GCGR expression
|
US20130071403A1
(en)
|
2011-09-20 |
2013-03-21 |
Vical Incorporated |
Synergistic anti-tumor efficacy using alloantigen combination immunotherapy
|
US20130085139A1
(en)
|
2011-10-04 |
2013-04-04 |
Royal Holloway And Bedford New College |
Oligomers
|
BR112014009790A2
(pt)
|
2011-10-25 |
2018-05-15 |
Isis Pharmaceuticals Inc |
composto para modulação antisense da expressão de gccr, seu uso e composição
|
CA2852633C
(en)
|
2011-10-28 |
2021-08-03 |
Oncotherapy Science, Inc. |
Topk peptides and vaccines including the same
|
KR102083957B1
(ko)
|
2011-12-05 |
2020-03-04 |
노파르티스 아게 |
표피 성장 인자 수용체 3 (her3)에 대한 항체
|
KR20140103135A
(ko)
|
2011-12-05 |
2014-08-25 |
노파르티스 아게 |
Her3의 도메인 ii에 대해 지시된 표피 성장 인자 수용체 3 (her3)에 대한 항체
|
WO2013084208A2
(pt)
|
2011-12-07 |
2013-06-13 |
Universidade Do Minho |
Lipossomas e respetivo método de produção
|
ES2710916T3
(es)
|
2011-12-22 |
2019-04-29 |
I2 Pharmaceuticals Inc |
Proteínas de unión sustitutas
|
EP3539982A3
(de)
|
2011-12-23 |
2020-01-15 |
Pfizer Inc |
Konstante regionen gentechnisch hergestellter antikörper für stellenspezifische konjugation sowie verfahren und verwendungen dafür
|
CA2860676A1
(en)
|
2012-01-09 |
2013-07-18 |
Novartis Ag |
Organic compositions to treat beta-catenin-related diseases
|
CN104185681A
(zh)
|
2012-02-01 |
2014-12-03 |
卡姆普根有限公司 |
C1orf32抗体及其用于治疗癌症的用途
|
PE20141791A1
(es)
|
2012-02-13 |
2014-11-19 |
Bristol Myers Squibb Co |
Compuestos de enediino, conjugados de los mismos y sus usos y metodos
|
WO2013126797A1
(en)
|
2012-02-24 |
2013-08-29 |
Purdue Research Foundation |
Cholecystokinin b receptor targeting for imaging and therapy
|
HUE040179T2
(hu)
|
2012-03-15 |
2019-02-28 |
Curna Inc |
Agyi eredetû neutrotróf faktorral (Brain-derived neurotrophic factor, BDNF) összefüggõ betegségek kezelése a BDNF-fel kapcsolatos természetes antiszensz transzkriptumok gátlása révén
|
NZ631034A
(en)
|
2012-03-16 |
2016-06-24 |
Merck Patent Gmbh |
Targeting aminoacid lipids
|
ES2700742T3
(es)
|
2012-03-16 |
2019-02-19 |
Merck Patent Gmbh |
Lípidos aminoácidos
|
WO2013142796A2
(en)
|
2012-03-23 |
2013-09-26 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla4 antibodies
|
US20140080175A1
(en)
|
2012-03-29 |
2014-03-20 |
Endocyte, Inc. |
Processes for preparing tubulysin derivatives and conjugates thereof
|
US9181572B2
(en)
|
2012-04-20 |
2015-11-10 |
Abbvie, Inc. |
Methods to modulate lysine variant distribution
|
WO2013167153A1
(en)
|
2012-05-09 |
2013-11-14 |
Ganymed Pharmaceuticals Ag |
Antibodies useful in cancer diagnosis
|
CA3062003C
(en)
|
2012-05-17 |
2022-01-11 |
Extend Biosciences, Inc. |
Vitamin d as a targeting group for therapeutic peptides
|
WO2013176754A1
(en)
|
2012-05-24 |
2013-11-28 |
Abbvie Inc. |
Novel purification of antibodies using hydrophobic interaction chromatography
|
EP2855520B1
(de)
|
2012-06-04 |
2018-09-26 |
Novartis AG |
Verfahren zur stellenspezifischen markierung und dadurch hergestellte moleküle
|
US9890215B2
(en)
|
2012-06-22 |
2018-02-13 |
King's College London |
Vista modulators for diagnosis and treatment of cancer
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
PL2890717T3
(pl)
|
2012-08-31 |
2020-08-10 |
Immunogen, Inc. |
Testy i zestawy diagnostyczne do wykrywania receptora folianu
|
CA2884704C
(en)
|
2012-09-07 |
2023-04-04 |
Randolph J. Noelle |
Vista modulators for diagnosis and treatment of cancer
|
US20160136159A1
(en)
|
2012-09-17 |
2016-05-19 |
Chemedest Ltd. |
Method for Treating Peripheral Neuropathy
|
WO2014055493A1
(en)
|
2012-10-02 |
2014-04-10 |
Cerulean Pharma Inc. |
Methods and systems for polymer precipitation and generation of particles
|
CA2887727A1
(en)
|
2012-10-16 |
2014-04-24 |
Endocyte, Inc. |
Drug delivery conjugates containing unnatural amino acids and methods for using
|
AU2013335004B2
(en)
|
2012-10-22 |
2018-06-28 |
Oneness Biotech Co. LTD |
Antibodies to interleukin-6 and uses thereof
|
US20150299803A1
(en)
|
2012-11-05 |
2015-10-22 |
Pronai Therapeutics, Inc. |
Methods of Using Biomarkers for the Treatment of Cancer by Modulation of BCL2 Expression
|
JP2015536339A
(ja)
|
2012-11-09 |
2015-12-21 |
ファイザー・インク |
血小板由来増殖因子b特異的抗体ならびにこれらの組成物および使用
|
KR102182523B1
(ko)
|
2012-12-18 |
2020-11-25 |
노파르티스 아게 |
안정화된 인슐린-유사 성장 인자 폴리펩티드
|
DK2953976T3
(da)
|
2013-02-08 |
2021-06-21 |
Novartis Ag |
Specifikke modificeringssteder i antistoffer til fremstilling af immunkonjugater
|
WO2014124258A2
(en)
|
2013-02-08 |
2014-08-14 |
Irm Llc |
Specific sites for modifying antibodies to make immunoconjugates
|
UY35315A
(es)
|
2013-02-08 |
2014-09-30 |
Novartis Ag |
Anticuerpos anti-il-17a y su uso en el tratamiento de trastornos autoinmunes e inflamatorios
|
MX356698B
(es)
|
2013-02-14 |
2018-06-11 |
Bristol Myers Squibb Co |
Compuestos de tubulisina, metodos para obtenerlos y uso.
|
US9498532B2
(en)
|
2013-03-13 |
2016-11-22 |
Novartis Ag |
Antibody drug conjugates
|
WO2014159239A2
(en)
|
2013-03-14 |
2014-10-02 |
Novartis Ag |
Antibodies against notch 3
|
CA2899449A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbvie Inc. |
Low acidic species compositions and methods for producing the same using displacement chromatography
|
BR112015017307A2
(pt)
|
2013-03-14 |
2017-11-21 |
Abbvie Inc |
composições de espécies com baixa acidez e métodos para produção e uso das mesmas
|
US9308236B2
(en)
|
2013-03-15 |
2016-04-12 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
|
US10052364B2
(en)
|
2013-03-15 |
2018-08-21 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for cognitive disorders
|
EP2968590B1
(de)
|
2013-03-15 |
2018-09-05 |
Novartis AG |
Antikörper-wirkstoff-konjugate
|
WO2014197938A1
(en)
|
2013-06-13 |
2014-12-18 |
Antisense Therapeutics Ltd |
Combination therapy
|
US9718811B2
(en)
|
2013-06-26 |
2017-08-01 |
Helmholtz Zentrum München—Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
(S)-enantiomer of mepazine
|
HUE042903T2
(hu)
|
2013-08-14 |
2019-07-29 |
Inst Of Genetics And Developmental Biology |
Eljárások mag- és szervméret modulálására növényekben
|
WO2015031815A2
(en)
|
2013-08-30 |
2015-03-05 |
Immunogen, Inc. |
Antibodies and assays for detection of folate receptor 1
|
CN111235149B
(zh)
|
2013-09-05 |
2024-04-16 |
萨罗塔治疗公司(美国) |
酸性α-葡糖苷酶中反义诱导的外显子2纳入
|
WO2015036643A2
(es)
|
2013-09-13 |
2015-03-19 |
Sierra Jiménez Angels |
Marcador para predecir metástasis del cancer de mama
|
US10036020B2
(en)
|
2013-09-19 |
2018-07-31 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Compositions and methods for inhibiting JC virus (JCV)
|
WO2015050959A1
(en)
|
2013-10-01 |
2015-04-09 |
Yale University |
Anti-kit antibodies and methods of use thereof
|
WO2015049630A1
(en)
|
2013-10-02 |
2015-04-09 |
Novartis Ag |
Insulin-like growth factor mimetics for use in therapy
|
PE20160561A1
(es)
|
2013-10-11 |
2016-06-03 |
Oxford Biotherapeutics Ltd |
Anticuerpos conjugados contra ly75 para el tratamiento de cancer
|
GB201319876D0
(en)
|
2013-11-11 |
2013-12-25 |
Plant Bioscience Ltd |
Methods of modulating seed and organ size in plants
|
SG10201810298VA
(en)
|
2013-11-13 |
2018-12-28 |
Pfizer |
Tumor necrosis factor-like ligand 1a specific antibodies and compositions and uses thereof
|
US11162937B2
(en)
|
2013-11-19 |
2021-11-02 |
Purdue Research Foundation |
Patient selection method for inflammation
|
UY35874A
(es)
|
2013-12-12 |
2015-07-31 |
Novartis Ag |
Un proceso para la preparación de una composición de proteínas pegiladas
|
MX369173B
(es)
|
2013-12-24 |
2019-10-30 |
Janssen Pharmaceutica Nv |
Anticuerpos y fragmentos anti-vista.
|
US11014987B2
(en)
|
2013-12-24 |
2021-05-25 |
Janssen Pharmaceutics Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
WO2015109212A1
(en)
|
2014-01-17 |
2015-07-23 |
Pfizer Inc. |
Anti-il-2 antibodies and compositions and uses thereof
|
WO2015116902A1
(en)
|
2014-01-31 |
2015-08-06 |
Genentech, Inc. |
G-protein coupled receptors in hedgehog signaling
|
AU2015214264B2
(en)
|
2014-02-04 |
2018-12-20 |
Curis, Inc. |
Mutant Smoothened and methods of using the same
|
CN106659800A
(zh)
|
2014-03-12 |
2017-05-10 |
诺华股份有限公司 |
用于修饰抗体以制备免疫缀合物的特定位点
|
WO2015171918A2
(en)
|
2014-05-07 |
2015-11-12 |
Louisiana State University And Agricultural And Mechanical College |
Compositions and uses for treatment thereof
|
GB201408623D0
(en)
|
2014-05-15 |
2014-07-02 |
Santaris Pharma As |
Oligomers and oligomer conjugates
|
SG10201810507WA
(en)
|
2014-06-06 |
2018-12-28 |
Bristol Myers Squibb Co |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
CN107073109B
(zh)
|
2014-06-11 |
2021-08-06 |
凯西·A·格林 |
Vista激动剂和拮抗剂抑制或增强体液免疫的用途
|
EP3161001A2
(de)
|
2014-06-25 |
2017-05-03 |
Novartis AG |
Il17-a spezifische antikörper die mit hyaluronan bindenden peptid-marker fusioniert sind
|
WO2015200901A1
(en)
|
2014-06-26 |
2015-12-30 |
The Trustees Of Columbia University In The City Of New York |
Inhibition of serotonin expression in gut enteroendocrine cells results in conversion to insulin-positive cells
|
US20170226552A1
(en)
|
2014-07-03 |
2017-08-10 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using cobalt
|
US20160185848A1
(en)
|
2014-07-09 |
2016-06-30 |
Abbvie Inc. |
Methods for modulating the glycosylation profile of recombinant proteins using sugars
|
US20170291956A1
(en)
|
2014-07-16 |
2017-10-12 |
David Livingston |
HER3 Inhibition in Low-grade Serous Ovarian Cancers
|
US10786578B2
(en)
|
2014-08-05 |
2020-09-29 |
Novartis Ag |
CKIT antibody drug conjugates
|
EP3180024B1
(de)
|
2014-08-11 |
2022-05-18 |
University of Massachusetts |
Anti-ospa-antikörper und verfahren zur verwendung
|
WO2016024195A1
(en)
|
2014-08-12 |
2016-02-18 |
Novartis Ag |
Anti-cdh6 antibody drug conjugates
|
WO2016033424A1
(en)
|
2014-08-29 |
2016-03-03 |
Genzyme Corporation |
Methods for the prevention and treatment of major adverse cardiovascular events using compounds that modulate apolipoprotein b
|
EP2993174A1
(de)
|
2014-09-08 |
2016-03-09 |
Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH |
Pyrazolopyridinderivate und deren Verwendung in der Therapie
|
US9732119B2
(en)
|
2014-10-10 |
2017-08-15 |
Bristol-Myers Squibb Company |
Immunomodulators
|
US9616109B2
(en)
|
2014-10-22 |
2017-04-11 |
Extend Biosciences, Inc. |
Insulin vitamin D conjugates
|
EP3220961B1
(de)
|
2014-10-22 |
2023-07-05 |
Extend Biosciences, Inc. |
Therapeutische vitamin-d-konjugate
|
US9789197B2
(en)
|
2014-10-22 |
2017-10-17 |
Extend Biosciences, Inc. |
RNAi vitamin D conjugates
|
WO2016075137A1
(en)
|
2014-11-10 |
2016-05-19 |
Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Spiropyrazine derivatives as inhibitors of non-apoptotic regulated cell-death
|
US10077287B2
(en)
|
2014-11-10 |
2018-09-18 |
Bristol-Myers Squibb Company |
Tubulysin analogs and methods of making and use
|
JOP20200092A1
(ar)
|
2014-11-10 |
2017-06-16 |
Alnylam Pharmaceuticals Inc |
تركيبات iRNA لفيروس الكبد B (HBV) وطرق لاستخدامها
|
US9856292B2
(en)
|
2014-11-14 |
2018-01-02 |
Bristol-Myers Squibb Company |
Immunomodulators
|
UY36401A
(es)
|
2014-11-14 |
2016-06-30 |
Novartis Ag |
Conjugados anticuerpos-fármacos
|
JP7175608B2
(ja)
|
2014-11-19 |
2022-11-21 |
ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク |
加齢に伴うフレイルのための治療としてのオステオカルシン
|
NZ731633A
(en)
|
2014-11-21 |
2022-01-28 |
Bristol Myers Squibb Co |
Antibodies against cd73 and uses thereof
|
PL3221346T3
(pl)
|
2014-11-21 |
2021-03-08 |
Bristol-Myers Squibb Company |
Przeciwciała ze zmodyfikowanym regionem stałym łańcucha ciężkiego
|
EA037590B1
(ru)
|
2014-11-25 |
2021-04-19 |
Бристол-Майерс Сквибб Компани |
Связывающиеся с pd-l1 полипептиды на основе 10fn3 домена для визуализации
|
BR112017010414A2
(pt)
|
2014-11-25 |
2018-05-15 |
Bristol-Myers Squibb Company |
métodos e composições para radiomarcação com 18f de substâncias biológicas
|
EP3227341A1
(de)
|
2014-12-02 |
2017-10-11 |
CeMM - Forschungszentrum für Molekulare Medizin GmbH |
Anti-mutante calreticulin-antikörper und deren verwendung bei der diagnose und therapie von myeloiden malignomen
|
WO2016090347A1
(en)
|
2014-12-05 |
2016-06-09 |
Immunext, Inc. |
Identification of vsig8 as the putative vista receptor and its use thereof to produce vista/vsig8 modulators
|
WO2016092508A1
(en)
|
2014-12-12 |
2016-06-16 |
Massachusetts General Hospital |
Treatment of breast cancer brain metastases
|
US9861680B2
(en)
|
2014-12-18 |
2018-01-09 |
Bristol-Myers Squibb Company |
Immunomodulators
|
EP3945096A1
(de)
|
2014-12-19 |
2022-02-02 |
Regenesance B.V. |
Antikörper zur bindung von humanem c6 und verwendungen davon
|
US9944678B2
(en)
|
2014-12-19 |
2018-04-17 |
Bristol-Myers Squibb Company |
Immunomodulators
|
SG10202006538TA
(en)
|
2014-12-23 |
2020-08-28 |
Bristol Myers Squibb Co |
Antibodies to tigit
|
ES2747386T3
(es)
|
2015-01-14 |
2020-03-10 |
Bristol Myers Squibb Co |
Dímeros de benzodiacepina unidos por heteroarileno, conjugados de los mismos y métodos de preparación y uso
|
TW201632202A
(zh)
|
2015-01-30 |
2016-09-16 |
諾華公司 |
乳癌之治療
|
US20160222060A1
(en)
|
2015-02-04 |
2016-08-04 |
Bristol-Myers Squibb Company |
Immunomodulators
|
WO2016144773A1
(en)
|
2015-03-06 |
2016-09-15 |
Abbvie Inc. |
Arabinosylated glycoproteins
|
WO2016145085A2
(en)
|
2015-03-09 |
2016-09-15 |
Celldex Therapeutics, Inc. |
Cd27 agonists
|
US9809625B2
(en)
|
2015-03-18 |
2017-11-07 |
Bristol-Myers Squibb Company |
Immunomodulators
|
MA41795A
(fr)
|
2015-03-18 |
2018-01-23 |
Sarepta Therapeutics Inc |
Exclusion d'un exon induite par des composés antisens dans la myostatine
|
CA2979826A1
(en)
|
2015-04-10 |
2016-10-13 |
Ruth Brack-Werner |
Pyrone derivatives for use in therapy
|
KR20170141692A
(ko)
|
2015-05-01 |
2017-12-26 |
알리스타 파마슈티컬즈, 인크. |
안구 장애를 치료하기 위한 아디포넥틴 펩티드모방체
|
AU2016263198C1
(en)
|
2015-05-15 |
2023-10-05 |
The General Hospital Corporation |
Antagonistic anti-tumor necrosis factor receptor superfamily antibodies
|
WO2016188932A2
(en)
|
2015-05-22 |
2016-12-01 |
Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Combination compositions and their use in methods for treating obesity and obesity-related disorders
|
JP2018522825A
(ja)
*
|
2015-05-26 |
2018-08-16 |
ザ ジェネラル ホスピタル コーポレイション |
リポソームナノ構造並びにそれを製造及び使用する方法
|
PE20180926A1
(es)
|
2015-05-29 |
2018-06-08 |
Bristol Myers Squibb Co |
Anticuerpos contra el miembro 4 de la superfamilia del receptor del factor de necrosis tumoral (ox40) y sus usos
|
MA50829A
(fr)
|
2015-06-01 |
2018-04-11 |
Sarepta Therapeutics Inc |
Exclusion d'exon induite pat technologie antisens dans le collagène de type vii
|
US20190194315A1
(en)
|
2015-06-17 |
2019-06-27 |
Novartis Ag |
Antibody drug conjugates
|
BR112017027870A2
(pt)
|
2015-06-24 |
2018-08-28 |
Janssen Pharmaceutica Nv |
anticorpos e fragmentos anti-vista
|
JP2018526977A
(ja)
|
2015-06-29 |
2018-09-20 |
ザ ロックフェラー ユニヴァーシティ |
アゴニスト活性が増強されたcd40に対する抗体
|
ES2896055T3
(es)
|
2015-07-13 |
2022-02-23 |
Compugen Ltd |
Composiciones de HIDE1 y métodos
|
US11066481B2
(en)
|
2015-07-23 |
2021-07-20 |
The Regents Of The University Of California |
Antibodies to coagulation factor XIa and uses thereof
|
US9862760B2
(en)
|
2015-09-16 |
2018-01-09 |
Novartis Ag |
Polyomavirus neutralizing antibodies
|
WO2017049149A1
(en)
|
2015-09-17 |
2017-03-23 |
Immunogen, Inc. |
Therapeutic combinations comprising anti-folr1 immunoconjugates
|
RU2638457C2
(ru)
|
2015-09-28 |
2017-12-13 |
Общество С Ограниченной Ответственностью "Онкомакс" |
Антитела, специфически связывающие рецептор 1 типа фактора роста фибробластов, применение антител для лечения онкологического заболевания, способ получения антител
|
US10954300B2
(en)
|
2015-09-28 |
2021-03-23 |
The Trustees Of Columbia University In The City Of New York |
Use of pentoxifylline with immune checkpoint-blockade therapies for the treatment of melanoma
|
WO2017059132A1
(en)
|
2015-09-29 |
2017-04-06 |
The General Hospital Corporation |
Methods of treating and diagnosing disease using biomarkers for bcg therapy
|
WO2017062835A2
(en)
|
2015-10-09 |
2017-04-13 |
Sarepta Therapeutics, Inc. |
Compositions and methods for treating duchenne muscular dystrophy and related disorders
|
EP3365369A1
(de)
|
2015-10-23 |
2018-08-29 |
Pfizer Inc |
Anti-il-2-antikörper sowie zusammensetzungen und verwendungen davon
|
MA44334A
(fr)
|
2015-10-29 |
2018-09-05 |
Novartis Ag |
Conjugués d'anticorps comprenant un agoniste du récepteur de type toll
|
CA3007424A1
(en)
|
2015-11-05 |
2017-05-11 |
Children's Hospital Los Angeles |
"mobilizing leukemia cells"
|
CN106699889A
(zh)
|
2015-11-18 |
2017-05-24 |
礼进生物医药科技(上海)有限公司 |
抗pd-1抗体及其治疗用途
|
WO2017087678A2
(en)
|
2015-11-19 |
2017-05-26 |
Bristol-Myers Squibb Company |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
PT3383920T
(pt)
|
2015-11-30 |
2024-04-15 |
Univ California |
Entrega de carga útil específica para tumores e ativação imune utilizando um anticorpo humano que tem como alvo um antigénio altamente específico da superfície das células tumorais
|
EP3383903A1
(de)
|
2015-11-30 |
2018-10-10 |
Bristol-Myers Squibb Company |
Humane ip-10-antikörper und deren verwendung
|
SG11201805341RA
(en)
|
2015-12-23 |
2018-07-30 |
Univ Queensland Technology |
Nucleic acid oligomers and uses therefor
|
EP3851457A1
(de)
|
2016-01-21 |
2021-07-21 |
Novartis AG |
Gegen cll-1 gerichtete multispezifische moleküle
|
AU2017213826A1
(en)
|
2016-02-04 |
2018-08-23 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
BR112018016461A2
(pt)
|
2016-02-12 |
2019-10-01 |
Janssen Pharmaceutica Nv |
anticorpos e fragmentos anti-vista, usos dos mesmos e métodos de identificação dos mesmos
|
BR112018015690A2
(pt)
|
2016-02-17 |
2018-12-26 |
Novartis Ag |
anticorpos tgfbeta 2
|
MX2018010672A
(es)
|
2016-03-04 |
2019-05-27 |
Univ Rockefeller |
Anticuerpos para cumulo de diferenciación 40 (cd40) con actividad agonista mejorada.
|
US10143746B2
(en)
|
2016-03-04 |
2018-12-04 |
Bristol-Myers Squibb Company |
Immunomodulators
|
EA201891983A8
(ru)
|
2016-03-04 |
2020-05-28 |
Бристол-Майерс Сквибб Компани |
Комбинированная терапия антителами к cd73
|
US10358463B2
(en)
|
2016-04-05 |
2019-07-23 |
Bristol-Myers Squibb Company |
Immunomodulators
|
MX2018012469A
(es)
|
2016-04-15 |
2019-07-04 |
Immunext Inc |
Anticuerpos vista antihumanos y uso de los mismos.
|
EA201892366A1
(ru)
|
2016-04-18 |
2019-03-29 |
Сарепта Терапьютикс, Инк. |
Антисмысловые олигомеры и способы их применения для лечения заболеваний, связанных с геном кислой альфа-глюкозидазы
|
EA201892362A1
(ru)
|
2016-04-18 |
2019-04-30 |
Селлдекс Терапьютикс, Инк. |
Агонистические антитела, которые связываются с cd40 человека, и варианты их применения
|
KR102565881B1
(ko)
|
2016-04-22 |
2023-08-10 |
비온테크 에스이 |
단일가닥 rna 제공 방법
|
LT3458111T
(lt)
|
2016-05-19 |
2021-05-25 |
Bristol-Myers Squibb Company |
Pet vizualizacijos imunomoduliatoriai
|
WO2017210302A1
(en)
|
2016-06-01 |
2017-12-07 |
Bristol-Myers Squibb Company |
Pet imaging with pd-l1 binding polypeptides
|
WO2017210335A1
(en)
|
2016-06-01 |
2017-12-07 |
Bristol-Myers Squibb Company |
Imaging methods using 18f-radiolabeled biologics
|
US20180002417A1
(en)
|
2016-06-15 |
2018-01-04 |
Celimmune Llc |
Methods and Compositions for the Treatment of Celiac Disease, Non-Celiac Gluten Sensitivity, and Refractory Celiac Disease
|
EP3260542A1
(de)
|
2016-06-20 |
2017-12-27 |
Algentech |
Proteinproduktion in pflanzenzellen
|
SG11201900026TA
(en)
|
2016-07-14 |
2019-01-30 |
Bristol Myers Squibb Co |
Antibodies against tim3 and uses thereof
|
JP7023933B2
(ja)
|
2016-08-19 |
2022-02-22 |
ブリストル-マイヤーズ スクイブ カンパニー |
セコ-シクロプロパピロロインドール化合物、その抗体-薬物コンジュゲート、ならびに製造および使用方法
|
WO2018044970A1
(en)
|
2016-08-31 |
2018-03-08 |
University Of Rochester |
Human monoclonal antibodies to human endogenous retrovirus k envelope (herv-k) and uses thereof
|
EP3305781A1
(de)
|
2016-10-07 |
2018-04-11 |
Deutsches Krebsforschungszentrum |
Chemische substanzen welche die enzymatische aktivität der humanen kallikrein-related peptidase 6 (klk6) hemmen.
|
CU20210030A7
(es)
|
2016-10-13 |
2021-11-04 |
Massachusetts Inst Technology |
Anticuerpos que se unen a la proteína de envoltura del virus zika
|
US10988507B2
(en)
|
2016-11-07 |
2021-04-27 |
Bristol-Myers Squibb Company |
Immunomodulators
|
US10538556B2
(en)
|
2016-11-07 |
2020-01-21 |
Colorado State University Research Foundation |
Anti-HIV peptides
|
US11434301B2
(en)
|
2016-11-11 |
2022-09-06 |
The Regents Of The University Of California |
Anti-CD46 antibodies and methods of use
|
CA3047707A1
(en)
|
2017-01-05 |
2018-07-12 |
Kahr Medical Ltd. |
A pd1-41bbl fusion protein and methods of use thereof
|
PT3565828T
(pt)
|
2017-01-05 |
2022-02-08 |
Kahr Medical Ltd |
Proteína de fusão sirp1 alfa-41bbl e seus métodos de utilização
|
JP7252526B2
(ja)
|
2017-01-23 |
2023-04-05 |
スチョー アルファマブ カンパニー リミテッド |
Pd-l1結合ポリペプチド又は化合物
|
JOP20190187A1
(ar)
|
2017-02-03 |
2019-08-01 |
Novartis Ag |
مترافقات عقار جسم مضاد لـ ccr7
|
JP7136790B2
(ja)
|
2017-02-17 |
2022-09-13 |
ブリストル-マイヤーズ スクイブ カンパニー |
アルファ-シヌクレインに対する抗体およびその使用
|
GB201703876D0
(en)
|
2017-03-10 |
2017-04-26 |
Berlin-Chemie Ag |
Pharmaceutical combinations
|
WO2018185618A1
(en)
|
2017-04-03 |
2018-10-11 |
Novartis Ag |
Anti-cdh6 antibody drug conjugates and anti-gitr antibody combinations and methods of treatment
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
US11324820B2
(en)
|
2017-04-18 |
2022-05-10 |
Alnylam Pharmaceuticals, Inc. |
Methods for the treatment of subjects having a hepatitis b virus (HBV) infection
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
WO2018209288A1
(en)
|
2017-05-12 |
2018-11-15 |
Massachusetts Institute Of Technology |
Argonaute protein-double stranded rna complexes and uses related thereto
|
EP3625251A1
(de)
|
2017-05-15 |
2020-03-25 |
University Of Rochester |
Breit neutralisierende monoklonale anti-influenza-antikörper und verwendungen davon
|
KR20200013241A
(ko)
|
2017-05-25 |
2020-02-06 |
브리스톨-마이어스 스큅 컴퍼니 |
변형된 중쇄 불변 영역을 포함하는 항체
|
WO2018226992A1
(en)
|
2017-06-07 |
2018-12-13 |
Adrx, Inc. |
Tau aggregation inhibitors
|
CA3068338A1
(en)
|
2017-06-23 |
2018-12-27 |
Suzhou Bojuhua Biomedical Technology Co. Ltd |
Monoclonal antibody targeting human tumor stem cells and use thereof
|
KR20200020858A
(ko)
|
2017-06-23 |
2020-02-26 |
브리스톨-마이어스 스큅 컴퍼니 |
Pd-1의 길항제로서 작용하는 면역조정제
|
EP3668886A2
(de)
|
2017-08-18 |
2020-06-24 |
Adrx, Inc. |
Peptidinhibitoren der tau-aggregation
|
JP2020531041A
(ja)
|
2017-08-28 |
2020-11-05 |
上海易楽生物技術有限公司 |
ポリペプチドとポリペプチドに結合される抗体
|
WO2019055460A1
(en)
|
2017-09-13 |
2019-03-21 |
The Children's Medical Center Corporation |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF TRANSPOSON-ASSOCIATED DISEASES
|
KR20200058506A
(ko)
|
2017-10-03 |
2020-05-27 |
브리스톨-마이어스 스큅 컴퍼니 |
면역조정제
|
WO2019075090A1
(en)
|
2017-10-10 |
2019-04-18 |
Tilos Therapeutics, Inc. |
ANTI-LAP ANTIBODIES AND USES THEREOF
|
EP3697910A4
(de)
|
2017-10-18 |
2021-07-14 |
Sarepta Therapeutics, Inc. |
Antisense-oligomer-verbindungen
|
US10973878B2
(en)
|
2017-10-26 |
2021-04-13 |
Immuneonco Biopharmaceuticals (Shanghai) Co., Ltd. |
Recombinant fusion protein containing an anti-PD-L1 antibody
|
KR20200074214A
(ko)
|
2017-11-01 |
2020-06-24 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하는데 사용하기 위한 면역자극 효능작용 항체
|
BR112020008438A2
(pt)
|
2017-11-02 |
2020-10-20 |
Oxford Biotherapeutics Ltd |
anticorpos e métodos de uso
|
CN111417651B
(zh)
|
2017-12-01 |
2023-09-29 |
诺华股份有限公司 |
多瘤病毒中和抗体
|
US10875915B2
(en)
|
2017-12-01 |
2020-12-29 |
Pfizer Inc. |
Anti-CXCR5 antibodies and compositions and uses thereof
|
RU2756100C1
(ru)
|
2017-12-20 |
2021-09-28 |
Харбор Байомед (Шанхай) Ко., Лтд |
Антитела, связывающие ctla-4, и их применение
|
JP2021507944A
(ja)
|
2017-12-21 |
2021-02-25 |
グリアファーム エスエー |
運動ニューロン疾患を含む神経障害のための組成物および治療方法
|
KR20200103680A
(ko)
|
2017-12-21 |
2020-09-02 |
글리아팜 에스에이 |
치매를 포함하는 신경 장애에 대한 치료 조성물 및 방법
|
EP3732198A1
(de)
|
2017-12-27 |
2020-11-04 |
Bristol-Myers Squibb Company |
Anti-cd40-antikörper und verwendungen davon
|
CN111886255A
(zh)
|
2018-01-12 |
2020-11-03 |
百时美施贵宝公司 |
抗tim3抗体及其用途
|
JP7416705B2
(ja)
|
2018-03-15 |
2024-01-17 |
バイオエヌテック エスエー |
5’キャップトリヌクレオチドまたはより高級のオリゴヌクレオチド化合物、ならびにrnaの安定化、タンパク質の発現および治療法におけるそれらの使用
|
TW202003565A
(zh)
|
2018-03-23 |
2020-01-16 |
美商必治妥美雅史谷比公司 |
抗mica及/或micb抗體及其用途
|
EP3777889A4
(de)
|
2018-03-26 |
2022-01-26 |
Shanghai Yile Biotechnology Co., Ltd. |
Verwendung von probdnf-regulator in b-zell-verwandten krankheiten
|
WO2019185129A1
(en)
|
2018-03-27 |
2019-10-03 |
The University Court Of The University Of Glasgow |
Bacterial pathogen derived resistance in plants
|
EP3774863A1
(de)
|
2018-03-29 |
2021-02-17 |
Pfizer Inc |
Lfa3-varianten sowie zusammensetzungen und verwendungen davon
|
EA202092302A1
(ru)
|
2018-04-02 |
2021-02-02 |
Бристол-Майерс Сквибб Компани |
Антитела к trem-1 и их применения
|
AU2019247490A1
(en)
|
2018-04-06 |
2020-10-22 |
Children's Medical Center Corporation |
Compositions and methods for somatic cell reprogramming and modulating imprinting
|
EP3773714A1
(de)
|
2018-04-12 |
2021-02-17 |
Bristol-Myers Squibb Company |
Antikrebs-kombinationstherapie mit cd73-antagonist-antikörper und pd-1/pd-l1-achsen-antagonist-antikörper
|
KR20210011919A
(ko)
|
2018-04-17 |
2021-02-02 |
셀덱스 쎄라퓨틱스, 인크. |
항-cd27 항체 및 항-pd-l1 항체 및 이중특이적 작제물
|
US20210179602A1
(en)
|
2018-04-20 |
2021-06-17 |
Iomx Therapeutics Ag |
A 5-thiazolecarboxamide kinase inhibitor and uses thereof
|
EP3787678A1
(de)
|
2018-05-03 |
2021-03-10 |
University Of Rochester |
Monoklonale neuraminidase-antikörper gegen influenza und ihre verwendungen
|
US11932681B2
(en)
|
2018-05-31 |
2024-03-19 |
Novartis Ag |
Hepatitis B antibodies
|
BR112020024351A2
(pt)
|
2018-06-01 |
2021-02-23 |
Novartis Ag |
moléculas de ligação contra bcma e usos das mesmas
|
GB201809746D0
(en)
|
2018-06-14 |
2018-08-01 |
Berlin Chemie Ag |
Pharmaceutical combinations
|
EP3826659B1
(de)
|
2018-07-10 |
2024-06-19 |
Rush University Medical Center |
Immunmodulator zur verwendung bei der behandlung einer bakteriellen infektion
|
US20210214417A1
(en)
|
2018-07-11 |
2021-07-15 |
Kahr Medical Ltd. |
SIRPalpha-4-1BBL VARIANT FUSION PROTEIN AND METHODS OF USE THEREOF
|
JP7193058B2
(ja)
|
2018-08-08 |
2022-12-20 |
イミューンオンコ バイオファーマシューティカルズ (シャンハイ) インコーポレイテッド |
Cd47およびher2を標的とする組換え二機能性タンパク質
|
MX2021001056A
(es)
|
2018-08-13 |
2021-04-12 |
Alnylam Pharmaceuticals Inc |
Composiciones de agente de acido ribonucleico bicatenario (arnbc) de virus de la hepatitis b (vhb) y metodos de uso de las mismas.
|
EP3847194A1
(de)
|
2018-09-07 |
2021-07-14 |
Pfizer Inc. |
Anti-avb8-antikörper sowie zusammensetzungen und verwendungen davon
|
WO2020053742A2
(en)
|
2018-09-10 |
2020-03-19 |
Novartis Ag |
Anti-hla-hbv peptide antibodies
|
CN113164780A
(zh)
|
2018-10-10 |
2021-07-23 |
泰洛斯治疗公司 |
抗lap抗体变体及其用途
|
WO2020084005A1
(en)
|
2018-10-23 |
2020-04-30 |
Myelopro Diagnostics And Research Gmbh |
Compounds targeting mutant calreticulin
|
EP3643713A1
(de)
|
2018-10-23 |
2020-04-29 |
iOmx Therapeutics AG |
Heterocyclische kinasehemmer und verwendungen davon
|
CA3117945A1
(en)
|
2018-11-09 |
2020-05-14 |
University Of Massachusetts |
Anti-cfae antibodies and methods of use
|
US11274150B2
(en)
|
2018-11-16 |
2022-03-15 |
Bristol-Myers Squibb Company |
Anti-human natural killer cell inhibitory receptor group 2A protein (NKG2A) antibodies
|
CN113348177A
(zh)
|
2018-11-28 |
2021-09-03 |
百时美施贵宝公司 |
包含经修饰的重链恒定区的抗体
|
TW202039554A
(zh)
|
2018-12-19 |
2020-11-01 |
瑞士商諾華公司 |
抗TNF-α抗體
|
CN113195541A
(zh)
|
2018-12-21 |
2021-07-30 |
诺华股份有限公司 |
针对pmel17的抗体及其缀合物
|
US20220056135A1
(en)
|
2018-12-21 |
2022-02-24 |
Ose Immunotherapeutics |
Bifunctional anti-pd-1/sirpa molecule
|
CA3122899A1
(en)
|
2018-12-21 |
2020-06-25 |
Ose Immunotherapeutics |
Bifunctional molecule directed against human pd-1
|
JP2022514702A
(ja)
|
2018-12-21 |
2022-02-14 |
オーエスイー・イミュノセラピューティクス |
二機能性抗pd-1/il-7分子
|
WO2020127366A1
(en)
|
2018-12-21 |
2020-06-25 |
Ose Immunotherapeutics |
Humanized anti-human-pd-1 antibody
|
WO2020132378A2
(en)
|
2018-12-22 |
2020-06-25 |
Gliapharm Sa |
Compositions and methods of treatment for neurological disorders comprising depression
|
CN109762067B
(zh)
|
2019-01-17 |
2020-02-28 |
北京天广实生物技术股份有限公司 |
结合人Claudin 18.2的抗体及其用途
|
WO2020165374A1
(en)
|
2019-02-14 |
2020-08-20 |
Ose Immunotherapeutics |
Bifunctional molecule comprising il-15ra
|
AU2020234394B2
(en)
|
2019-03-08 |
2024-02-15 |
AbTis Co., Ltd. |
Site-specific antibody conjugation and antibody-drug conjugate as specific example thereof
|
CA3135032A1
(en)
|
2019-04-03 |
2020-10-08 |
Genzyme Corporation |
Anti-alpha beta tcr binding polypeptides with reduced fragmentation
|
CN113853219A
(zh)
|
2019-05-20 |
2021-12-28 |
诺华股份有限公司 |
具有包含亲水性基团的接头的抗体药物缀合物
|
WO2020237081A1
(en)
|
2019-05-21 |
2020-11-26 |
Bristol-Myers Squibb Company |
Immunomodulators
|
EP3994172A1
(de)
|
2019-07-03 |
2022-05-11 |
Oxford BioTherapeutics Ltd |
Antikörper und verfahren zur verwendung
|
WO2021005599A1
(en)
|
2019-07-11 |
2021-01-14 |
Kahr Medical Ltd. |
Heterodimers and methods of use thereof
|
EP3999541A1
(de)
|
2019-07-15 |
2022-05-25 |
Bristol-Myers Squibb Company |
Antikörper gegen menschlichen trem-1 und ihre verwendungen
|
CN114174536A
(zh)
|
2019-07-15 |
2022-03-11 |
百时美施贵宝公司 |
抗trem-1抗体及其用途
|
KR20220088868A
(ko)
|
2019-10-30 |
2022-06-28 |
브리스톨-마이어스 스큅 컴퍼니 |
면역조정제
|
ES2970395T3
(es)
|
2019-11-19 |
2024-05-28 |
Bristol Myers Squibb Co |
Péptidos macrocíclicos como inhibidores de PD-L1 e inmunomoduladores para el tratamiento de cáncer y enfermedades infecciosas
|
KR20220122752A
(ko)
|
2020-01-06 |
2022-09-02 |
브리스톨-마이어스 스큅 컴퍼니 |
면역조정제
|
US20230063238A1
(en)
|
2020-01-06 |
2023-03-02 |
Bristol-Myers Squibb Company |
Immunomodulators
|
KR20220147642A
(ko)
|
2020-02-27 |
2022-11-03 |
치아타이 티안큉 파마수티컬 그룹 주식회사 |
Il4r에 결합하는 항체 및 이의 용도
|
WO2021174045A1
(en)
|
2020-02-28 |
2021-09-02 |
Bristol-Myers Squibb Company |
Radiolabeled fibronectin based scaffolds and antibodies and theranostic uses thereof
|
EP4118118A1
(de)
|
2020-03-09 |
2023-01-18 |
Bristol-Myers Squibb Company |
Antikörper gegen cd40 mit verbesserter agonistenaktivität
|
CN115485288A
(zh)
|
2020-03-16 |
2022-12-16 |
百时美施贵宝公司 |
免疫调节剂
|
WO2021202501A1
(en)
|
2020-03-30 |
2021-10-07 |
Bristol-Myers Squibb Company |
Immunomodulators
|
CA3170570A1
(en)
|
2020-04-01 |
2021-10-07 |
James J. KOBIE |
Monoclonal antibodies against the hemagglutinin (ha) and neuraminidase (na) of influenza h3n2 viruses
|
EP4132971A1
(de)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinitätsgereifte anti-lap-antikörper und verwendungen davon
|
EP3901151A1
(de)
|
2020-04-21 |
2021-10-27 |
iOmx Therapeutics AG |
Halogenierte heteroaryl- und andere heterocyclische kinaseinhibitoren und verwendungen davon
|
EP3921034A2
(de)
|
2020-04-28 |
2021-12-15 |
The Rockefeller University |
Neutralisierende anti-sars-cov-2-antikörper und verfahren zu deren verwendung
|
IL297714A
(en)
|
2020-04-28 |
2022-12-01 |
Iomx Therapeutics Ag |
Bicyclic kinase inhibitors and their uses
|
US20230181756A1
(en)
|
2020-04-30 |
2023-06-15 |
Novartis Ag |
Ccr7 antibody drug conjugates for treating cancer
|
JP2023523760A
(ja)
|
2020-05-01 |
2023-06-07 |
ノバルティス アーゲー |
免疫グロブリン変異体
|
JP2023523794A
(ja)
|
2020-05-01 |
2023-06-07 |
ノバルティス アーゲー |
人工操作免疫グロブリン
|
JP2023524813A
(ja)
|
2020-05-08 |
2023-06-13 |
ブリストル-マイヤーズ スクイブ カンパニー |
免疫調節剤
|
US20230192867A1
(en)
|
2020-05-15 |
2023-06-22 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
US20230277524A1
(en)
|
2020-05-22 |
2023-09-07 |
Trailhead Biosystems Inc. |
Combination therapy for treatment of viral infections
|
JP2023534765A
(ja)
|
2020-08-07 |
2023-08-10 |
フォーティス セラピューティクス,インク. |
免疫複合体を標的とするcd46およびその使用方法
|
CA3191819A1
(en)
|
2020-09-09 |
2022-03-17 |
Hazel Szeto |
Methods and compositions for delivery of biotin to mitochondria
|
EP4221841A1
(de)
|
2020-10-02 |
2023-08-09 |
Bristol-Myers Squibb Company |
Makrocyclische peptidboronat-immunmodulatoren
|
WO2022076794A1
(en)
|
2020-10-08 |
2022-04-14 |
Bristol-Myers Squibb Company |
Dimeric milla immunomodulators
|
EP4225774A1
(de)
|
2020-10-09 |
2023-08-16 |
Bristol-Myers Squibb Company |
Makrocyclische immunomodulatoren
|
AR123997A1
(es)
|
2020-11-04 |
2023-02-01 |
Univ Rockefeller |
ANTICUERPOS NEUTRALIZANTES CONTRA EL SARS-CoV-2
|
IL302412A
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Anti-CD19 and B-cell targeting agent combination therapy for the treatment of B-cell malignancies
|
KR20230104651A
(ko)
|
2020-11-06 |
2023-07-10 |
노파르티스 아게 |
Cd19 결합 분자 및 이의 용도
|
JP2023547499A
(ja)
|
2020-11-06 |
2023-11-10 |
ノバルティス アーゲー |
抗体Fc変異体
|
KR20230107281A
(ko)
|
2020-11-11 |
2023-07-14 |
비온테크 에스이 |
프로그램된 사멸-1 단백질에 대한 모노클로날 항체 및 의약에서의 용도
|
CN114685669A
(zh)
|
2020-12-30 |
2022-07-01 |
和铂医药(苏州)有限公司 |
结合trop2的抗体及其用途
|
WO2022155324A1
(en)
|
2021-01-15 |
2022-07-21 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies
|
CN117157306A
(zh)
|
2021-03-24 |
2023-12-01 |
百时美施贵宝公司 |
免疫调节剂
|
CN117545773A
(zh)
|
2021-04-09 |
2024-02-09 |
塞德斯医疗公司 |
抗ilt4的抗体、双特异性抗ilt4/pd-l1抗体及其用途
|
JP2024516369A
(ja)
|
2021-04-12 |
2024-04-15 |
ブリストル-マイヤーズ スクイブ カンパニー |
環状ペプチド免疫調節剤
|
BR112023021475A2
(pt)
|
2021-04-16 |
2023-12-19 |
Novartis Ag |
Conjugados anticorpo-fármaco e métodos para produzir os mesmos
|
CA3214540A1
(en)
|
2021-04-22 |
2022-10-27 |
Pasi A. Janne |
Compositions and methods for treating cancer
|
WO2022235867A2
(en)
|
2021-05-06 |
2022-11-10 |
The Rockefeller University |
Neutralizing anti-sars- cov-2 antibodies and methods of use thereof
|
EP4346882A1
(de)
|
2021-05-26 |
2024-04-10 |
Oxford BioTherapeutics Ltd |
Pharmazeutische kombination mit einem anti-cd205-antikörper und einem immun-checkpoint-inhibitor
|
CA3217100A1
(en)
|
2021-06-09 |
2022-12-15 |
Gerald BURGSTALLER |
Novel anti-fibrotic drugs
|
EP4352077A1
(de)
|
2021-06-09 |
2024-04-17 |
Bristol-Myers Squibb Company |
Zyklische peptidimmunmodulatoren
|
KR20240034211A
(ko)
|
2021-07-12 |
2024-03-13 |
브리스톨-마이어스 스큅 컴퍼니 |
마크로시클릭 면역조정제
|
EP4373835A1
(de)
|
2021-07-19 |
2024-05-29 |
Bristol-Myers Squibb Company |
Makrocyclische immunmodulatoren
|
CN113773401B
(zh)
|
2021-09-15 |
2023-06-20 |
宜明昂科生物医药技术(上海)股份有限公司 |
靶向cd47和pd-l1的重组融合蛋白及其制备和用途
|
CN113956363B
(zh)
|
2021-10-13 |
2023-03-31 |
宜明昂科生物医药技术(上海)股份有限公司 |
靶向cd47和cd24的重组融合蛋白及其制备和用途
|
AU2022364888A1
(en)
|
2021-10-14 |
2024-05-30 |
Latticon (Suzhou) Biopharmaceuticals Co., Ltd. |
Novel antibody-cytokine fusion protein, preparation method therefor and use thereof
|
CN118159549A
(zh)
|
2021-10-20 |
2024-06-07 |
百时美施贵宝公司 |
免疫调节剂
|
WO2023073599A1
(en)
|
2021-10-28 |
2023-05-04 |
Novartis Ag |
Engineered fc variants
|
WO2023077521A1
(en)
|
2021-11-08 |
2023-05-11 |
Celldex Therapeutics, Inc |
Anti-ilt4 and anti-pd-1 bispecific constructs
|
WO2023089314A1
(en)
|
2021-11-18 |
2023-05-25 |
Oxford Biotherapeutics Limited |
Pharmaceutical combinations
|
WO2023102507A1
(en)
|
2021-12-03 |
2023-06-08 |
Bristol-Myers Squibb Company |
Macrocyclic immunomodulators
|
WO2023147399A1
(en)
|
2022-01-27 |
2023-08-03 |
The Rockefeller University |
Broadly neutralizing anti-sars-cov-2 antibodies targeting the n-terminal domain of the spike protein and methods of use thereof
|
WO2023192873A1
(en)
|
2022-03-28 |
2023-10-05 |
Bristol-Myers Squibb Company |
Macrocyclic immunomodulators
|
EP4257132A1
(de)
|
2022-04-08 |
2023-10-11 |
iOmx Therapeutics AG |
Sik3-inhibitoren zum behandeln von krankheiten, die gegen death-rezeptor -signaltransduktion resistent sind
|
EP4257609A1
(de)
|
2022-04-08 |
2023-10-11 |
iOmx Therapeutics AG |
Kombinationstherapien basierend auf pd-1-inhibitoren und sik3-inhibitoren
|
TW202400658A
(zh)
|
2022-04-26 |
2024-01-01 |
瑞士商諾華公司 |
靶向il—13和il—18的多特異性抗體
|
US11932693B2
(en)
|
2022-05-12 |
2024-03-19 |
BioNTech SE |
Monoclonal antibodies directed against programmed death-1 protein and their use in medicine
|
WO2023225661A1
(en)
|
2022-05-20 |
2023-11-23 |
Bristol-Myers Squibb Company |
Macrocyclic immunomodulators
|
WO2024059472A1
(en)
|
2022-09-12 |
2024-03-21 |
Bristol-Myers Squibb Company |
Macrocyclic immunomodulators
|
WO2024062074A1
(en)
|
2022-09-21 |
2024-03-28 |
Sanofi Biotechnology |
Humanized anti-il-1r3 antibody and methods of use
|