FI884838A0 - Nytt s-timololderivat och foerfarande foer dess framstaellning. - Google Patents

Nytt s-timololderivat och foerfarande foer dess framstaellning.

Info

Publication number
FI884838A0
FI884838A0 FI884838A FI884838A FI884838A0 FI 884838 A0 FI884838 A0 FI 884838A0 FI 884838 A FI884838 A FI 884838A FI 884838 A FI884838 A FI 884838A FI 884838 A0 FI884838 A0 FI 884838A0
Authority
FI
Finland
Prior art keywords
timololderivat
nytt
foerfarande foer
och foerfarande
foer dess
Prior art date
Application number
FI884838A
Other languages
English (en)
Other versions
FI82240B (fi
FI82240C (fi
FI884838A (fi
Inventor
Markku Peraelampi
Original Assignee
Huhtamaeki Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huhtamaeki Oy filed Critical Huhtamaeki Oy
Publication of FI884838A0 publication Critical patent/FI884838A0/fi
Priority to FI884838A priority Critical patent/FI82240C/fi
Priority to US07/663,853 priority patent/US5231095A/en
Priority to PCT/FI1989/000196 priority patent/WO1990004592A1/en
Priority to JP1510608A priority patent/JP2949508B2/ja
Priority to AU43473/89A priority patent/AU624431B2/en
Priority to DE68918597T priority patent/DE68918597T2/de
Priority to AT89911378T priority patent/ATE112277T1/de
Priority to EP89911378A priority patent/EP0440684B1/en
Priority to NZ231057A priority patent/NZ231057A/en
Priority to CA002001083A priority patent/CA2001083C/en
Publication of FI884838A publication Critical patent/FI884838A/fi
Publication of FI82240B publication Critical patent/FI82240B/fi
Application granted granted Critical
Publication of FI82240C publication Critical patent/FI82240C/fi
Priority to NO911508A priority patent/NO179838C/no
Priority to DK199100725A priority patent/DK175377B1/da
Priority to US07/910,789 priority patent/US5354860A/en
Priority to US08/097,880 priority patent/US5496820A/en
Priority to US08/319,868 priority patent/US5574035A/en
Priority to US08/320,327 priority patent/US5541184A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/101,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Control Of El Displays (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
FI884838A 1988-10-20 1988-10-20 Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat. FI82240C (fi)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FI884838A FI82240C (fi) 1988-10-20 1988-10-20 Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.
US07/663,853 US5231095A (en) 1988-10-20 1989-10-13 S-timolol hemihydrate
PCT/FI1989/000196 WO1990004592A1 (en) 1988-10-20 1989-10-13 Novel s-timolol derivative and process for its preparation
JP1510608A JP2949508B2 (ja) 1988-10-20 1989-10-13 新規なs―チモロール誘導体及びその製造方法
AU43473/89A AU624431B2 (en) 1988-10-20 1989-10-13 Novel s-timolol derivative and process for its preparation
DE68918597T DE68918597T2 (de) 1988-10-20 1989-10-13 Neues S-Timolol Derivat und Verfahren zu seiner Herstellung.
AT89911378T ATE112277T1 (de) 1988-10-20 1989-10-13 Neues s-timolol derivat und verfahren zu seiner herstellung.
EP89911378A EP0440684B1 (en) 1988-10-20 1989-10-13 Novel s-timolol derivative and process for its preparation
NZ231057A NZ231057A (en) 1988-10-20 1989-10-18 S-timolol hemihydrate and pharmaceutical compositions
CA002001083A CA2001083C (en) 1988-10-20 1989-10-20 Novel s-timolol derivative and process for its preparation
NO911508A NO179838C (no) 1988-10-20 1991-04-17 Fremgangsmåte for fremstilling av S-(-)-3-morfolino-4-(3-tert-butylamino-2-hydroksypropoksy)-1,2,5-tiadiazol-hemihydrat
DK199100725A DK175377B1 (da) 1988-10-20 1991-04-19 Hidtil ukendt S-timolol-derivat samt fremgangsmåde til fremstilling deraf
US07/910,789 US5354860A (en) 1988-10-20 1992-07-08 Process for making pure S-timolol hemihydrate
US08/097,880 US5496820A (en) 1988-10-20 1993-07-27 Ophthalmic use of S-timolol hemihydrate
US08/319,868 US5574035A (en) 1988-10-20 1994-10-07 S-timolol hemihydrate composition and method of preparation therefor
US08/320,327 US5541184A (en) 1988-10-20 1994-10-11 S-timolol hemihydrate treatment process

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI884838A FI82240C (fi) 1988-10-20 1988-10-20 Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.
FI884838 1988-10-20

Publications (4)

Publication Number Publication Date
FI884838A0 true FI884838A0 (fi) 1988-10-20
FI884838A FI884838A (fi) 1990-04-21
FI82240B FI82240B (fi) 1990-10-31
FI82240C FI82240C (fi) 1991-02-11

Family

ID=8527232

Family Applications (1)

Application Number Title Priority Date Filing Date
FI884838A FI82240C (fi) 1988-10-20 1988-10-20 Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.

Country Status (12)

Country Link
US (4) US5231095A (fi)
EP (1) EP0440684B1 (fi)
JP (1) JP2949508B2 (fi)
AT (1) ATE112277T1 (fi)
AU (1) AU624431B2 (fi)
CA (1) CA2001083C (fi)
DE (1) DE68918597T2 (fi)
DK (1) DK175377B1 (fi)
FI (1) FI82240C (fi)
NO (1) NO179838C (fi)
NZ (1) NZ231057A (fi)
WO (1) WO1990004592A1 (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI82240C (fi) * 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.
US5496820A (en) * 1988-10-20 1996-03-05 Peraelampi; Markku Ophthalmic use of S-timolol hemihydrate
TW208013B (fi) * 1990-03-01 1993-06-21 Daiichi Co Ltd
SG49770A1 (en) * 1992-07-08 1998-06-15 Santen Oy Pharmaceutical preparation
US20060143783A1 (en) * 2004-12-15 2006-07-06 Berman Paul K Energy diffusing glove insert
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
JP5313125B2 (ja) 2007-02-28 2013-10-09 旭化成ファーマ株式会社 スルホンアミド誘導体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657237A (en) * 1968-05-22 1972-04-18 Frosst & Co Charles E Process for making 1 2 5-thiadiazoles in the sinister configuration
US4428883A (en) * 1981-03-06 1984-01-31 The University Of Kentucky Research Foundation Novel method of administering β-blockers and novel dosage forms containing same
FI71933C (fi) * 1984-03-30 1989-04-06 Star Oy Ab Nya l-vinsyra-0-monoestrar av 3-morfolino-4-(3'-tert.-butylamino-2'-hydroxipropoxi)-1,2,5-tiadiazol och deras anvaendning saosom mellanprodukter.
JPS60226855A (ja) * 1984-04-26 1985-11-12 Nippon Kayaku Co Ltd N−ベンジルオキシカルボニル−l−スレオニンアミド・1/2水和物およびその製造法
US4752478A (en) * 1984-12-17 1988-06-21 Merck & Co., Inc. Transdermal system for timolol
US4756710A (en) * 1985-04-05 1988-07-12 Merck & Co., Inc. pH-Mediated drug delivery system
FI82240C (fi) * 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.

Also Published As

Publication number Publication date
EP0440684B1 (en) 1994-09-28
CA2001083C (en) 1999-06-15
WO1990004592A1 (en) 1990-05-03
US5231095A (en) 1993-07-27
NO179838C (no) 1996-12-27
FI82240B (fi) 1990-10-31
EP0440684A1 (en) 1991-08-14
ATE112277T1 (de) 1994-10-15
DK175377B1 (da) 2004-09-20
DE68918597T2 (de) 1995-05-11
NO911508D0 (no) 1991-04-17
US5541184A (en) 1996-07-30
DE68918597D1 (de) 1994-11-03
FI82240C (fi) 1991-02-11
US5574035A (en) 1996-11-12
NO911508L (no) 1991-04-17
JPH04502612A (ja) 1992-05-14
NO179838B (no) 1996-09-16
US5354860A (en) 1994-10-11
AU4347389A (en) 1990-05-14
NZ231057A (en) 1990-11-27
DK72591A (da) 1991-04-19
JP2949508B2 (ja) 1999-09-13
AU624431B2 (en) 1992-06-11
CA2001083A1 (en) 1990-04-20
DK72591D0 (da) 1991-04-19
FI884838A (fi) 1990-04-21

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Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: SANTEN OY

FG Patent granted

Owner name: SANTEN PHARMACEUTICAL CO., LTD

MA Patent expired