ATE554104T1 - Domänen der konstanten region von immunoglobulinen mit verbesserter stabilität - Google Patents
Domänen der konstanten region von immunoglobulinen mit verbesserter stabilitätInfo
- Publication number
- ATE554104T1 ATE554104T1 AT07755812T AT07755812T ATE554104T1 AT E554104 T1 ATE554104 T1 AT E554104T1 AT 07755812 T AT07755812 T AT 07755812T AT 07755812 T AT07755812 T AT 07755812T AT E554104 T1 ATE554104 T1 AT E554104T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- polypeptide
- immunoglobulin
- pro
- region domain
- Prior art date
Links
- 108060003951 Immunoglobulin Proteins 0.000 title abstract 6
- 102000018358 immunoglobulin Human genes 0.000 title abstract 6
- 229940072221 immunoglobulins Drugs 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 11
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 11
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 11
- 238000006467 substitution reaction Methods 0.000 abstract 5
- 239000012634 fragment Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 230000001594 aberrant effect Effects 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79420206P | 2006-04-21 | 2006-04-21 | |
| US86077406P | 2006-11-21 | 2006-11-21 | |
| PCT/US2007/009693 WO2007124077A2 (en) | 2006-04-21 | 2007-04-20 | Immunoglobulin constant region domains with enhanced stability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE554104T1 true ATE554104T1 (de) | 2012-05-15 |
Family
ID=38625624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07755812T ATE554104T1 (de) | 2006-04-21 | 2007-04-20 | Domänen der konstanten region von immunoglobulinen mit verbesserter stabilität |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2027154B1 (de) |
| AT (1) | ATE554104T1 (de) |
| AU (1) | AU2007240727B2 (de) |
| CA (1) | CA2649709A1 (de) |
| ES (1) | ES2387023T3 (de) |
| WO (1) | WO2007124077A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2011013455A (es) * | 2009-07-08 | 2012-02-13 | Amgen Inc | Diseño de moleculas de fc de anticuerpo estables y libres de agregacion a traves del diseño de la interfase del dominio de ch3. |
| EP3586860A1 (de) * | 2018-06-22 | 2020-01-01 | Universität Ulm | Komplement-inhibitoren und verwendungen davon |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
| US6277375B1 (en) * | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| EP1597372A2 (de) * | 2003-02-18 | 2005-11-23 | Syngeta Participations AG | Expression von e. coli enterotoxine spezifische antikörper in pflanzen |
-
2007
- 2007-04-20 AT AT07755812T patent/ATE554104T1/de active
- 2007-04-20 WO PCT/US2007/009693 patent/WO2007124077A2/en not_active Ceased
- 2007-04-20 ES ES07755812T patent/ES2387023T3/es active Active
- 2007-04-20 AU AU2007240727A patent/AU2007240727B2/en not_active Ceased
- 2007-04-20 CA CA002649709A patent/CA2649709A1/en not_active Abandoned
- 2007-04-20 EP EP07755812A patent/EP2027154B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP2027154A2 (de) | 2009-02-25 |
| WO2007124077A2 (en) | 2007-11-01 |
| EP2027154B1 (de) | 2012-04-18 |
| CA2649709A1 (en) | 2007-11-01 |
| AU2007240727A1 (en) | 2007-11-01 |
| ES2387023T3 (es) | 2012-09-11 |
| WO2007124077A3 (en) | 2008-08-07 |
| AU2007240727B2 (en) | 2013-12-19 |
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