SI2161283T1 - Sestavki, ki obsegajo protitelesa proti CD79b, konjugirana na sredstvo, ki inhibira rast, ali na citotoksično sredstvo, in postopki za zdravljenje tumorja hematopoetskega izvora - Google Patents

Sestavki, ki obsegajo protitelesa proti CD79b, konjugirana na sredstvo, ki inhibira rast, ali na citotoksično sredstvo, in postopki za zdravljenje tumorja hematopoetskega izvora

Info

Publication number
SI2161283T1
SI2161283T1 SI200432184T SI200432184T SI2161283T1 SI 2161283 T1 SI2161283 T1 SI 2161283T1 SI 200432184 T SI200432184 T SI 200432184T SI 200432184 T SI200432184 T SI 200432184T SI 2161283 T1 SI2161283 T1 SI 2161283T1
Authority
SI
Slovenia
Prior art keywords
compositions
tumor
treatment
methods
conjugated
Prior art date
Application number
SI200432184T
Other languages
English (en)
Inventor
Craig Crowley
Frederic J. Desauvage
Dan L. Eaton
Allen Ebens Jr.
Andrew Polson
Victoria Smith
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of SI2161283T1 publication Critical patent/SI2161283T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
SI200432184T 2003-11-17 2004-11-16 Sestavki, ki obsegajo protitelesa proti CD79b, konjugirana na sredstvo, ki inhibira rast, ali na citotoksično sredstvo, in postopki za zdravljenje tumorja hematopoetskega izvora SI2161283T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52084203P 2003-11-17 2003-11-17
US53242603P 2003-12-24 2003-12-24
EP09004091.6A EP2161283B1 (en) 2003-11-17 2004-11-16 Compositions comprising antibodies against CD79b conjugated to a growth inhibitory agent or cytotoxic agent and methods for the treatment of tumor of hematopoietic origin

Publications (1)

Publication Number Publication Date
SI2161283T1 true SI2161283T1 (sl) 2014-10-30

Family

ID=34623150

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200432184T SI2161283T1 (sl) 2003-11-17 2004-11-16 Sestavki, ki obsegajo protitelesa proti CD79b, konjugirana na sredstvo, ki inhibira rast, ali na citotoksično sredstvo, in postopki za zdravljenje tumorja hematopoetskega izvora
SI200432166T SI2295073T1 (sl) 2003-11-17 2004-11-16 Protitelo proti CD22 za zdravljenje tumorja hematopoetskega izvora

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200432166T SI2295073T1 (sl) 2003-11-17 2004-11-16 Protitelo proti CD22 za zdravljenje tumorja hematopoetskega izvora

Country Status (14)

Country Link
EP (5) EP1689432B1 (sl)
JP (4) JP4901478B2 (sl)
AT (1) ATE453405T1 (sl)
AU (2) AU2004291141B2 (sl)
CA (2) CA2546285C (sl)
DE (1) DE602004024921D1 (sl)
DK (2) DK2295073T3 (sl)
ES (3) ES2472690T3 (sl)
HK (1) HK1153931A1 (sl)
NZ (5) NZ578351A (sl)
PL (2) PL2161283T3 (sl)
PT (2) PT2161283E (sl)
SI (2) SI2161283T1 (sl)
WO (1) WO2005049075A2 (sl)

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US20110045005A1 (en) 2001-10-19 2011-02-24 Craig Crowley Compositions and methods for the treatment of tumor of hematopoietic origin
US20090068178A1 (en) * 2002-05-08 2009-03-12 Genentech, Inc. Compositions and Methods for the Treatment of Tumor of Hematopoietic Origin
WO2005117986A2 (en) 2004-06-01 2005-12-15 Genentech, Inc. Antibody drug conjugates and methods
CA2546285C (en) 2003-11-17 2015-12-29 Genentech, Inc. Compositions and methods for the treatment of tumor of hematopoietic origin
JP4658967B2 (ja) * 2003-12-24 2011-03-23 ジェネンテック， インコーポレイテッド 造血系起源の腫瘍の治療のための組成物と方法
KR20140085544A (ko) 2006-05-30 2014-07-07 제넨테크, 인크. 항체 및 면역접합체 및 이들의 용도
PT2474557E (pt) 2007-07-16 2014-12-03 Genentech Inc Anticorpos e imunoconjugados anti-cd79b e métodos de utilização
BRPI0813514A2 (pt) 2007-07-16 2019-09-24 Genentech Inc anticorpos anti-cd79b humanizados e imunoconjugados e métodos de uso
SI2247620T1 (sl) 2008-01-31 2016-09-30 Genentech, Inc. Protitelesa proti CD79b in imunokonjugati in postopki za uporabo
DK2260111T3 (en) 2008-03-14 2015-09-14 Genentech Inc Genetic variations that are associated with drug resistance
US11098115B2 (en) 2011-09-29 2021-08-24 Apo-T B.V. Multi-specific binding molecules targeting aberrant cells
US10946104B2 (en) * 2012-01-13 2021-03-16 Apo-Tb.V. Aberrant cell-restricted immunoglobulins provided with a toxic moiety
SG11201601005XA (en) 2013-08-12 2016-03-30 Genentech Inc 1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
WO2015095212A1 (en) 2013-12-16 2015-06-25 Genentech, Inc. 1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
GB201412658D0 (en) 2014-07-16 2014-08-27 Ucb Biopharma Sprl Molecules
AU2015320678B2 (en) 2014-09-23 2021-07-22 Genentech, Inc. Method of using anti-CD79b immunoconjugates
GB201601077D0 (en) 2016-01-20 2016-03-02 Ucb Biopharma Sprl Antibody molecule
GB201601075D0 (en) 2016-01-20 2016-03-02 Ucb Biopharma Sprl Antibodies molecules
GB201601073D0 (en) 2016-01-20 2016-03-02 Ucb Biopharma Sprl Antibodies
WO2017112829A1 (en) * 2015-12-22 2017-06-29 Abbvie Stemcentrx Llc Novel anti-upk1b antibodies and methods of use
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN111254156A (zh) * 2019-06-05 2020-06-09 南京艾德免疫治疗研究院有限公司 靶向人源化cd22的嵌合抗原受体及其用途

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