TWI480268B - 類鐸受體的調節劑 - Google Patents

類鐸受體的調節劑 Download PDF

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Publication number
TWI480268B
TWI480268B TW103102754A TW103102754A TWI480268B TW I480268 B TWI480268 B TW I480268B TW 103102754 A TW103102754 A TW 103102754A TW 103102754 A TW103102754 A TW 103102754A TW I480268 B TWI480268 B TW I480268B
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Taiwan
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formula
alkyl
compound
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TW103102754A
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TW201441204A (zh
Inventor
Manoj C Desai
Randall L Halcomb
Paul Hrvatin
Hon Chung Hui
Ryan Mcfadden
Paul A Roethle
Hong Yang
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Gilead Sciences Inc
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
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    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
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    • C07D475/10—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with an aromatic or hetero-aromatic ring directly attached in position 2
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    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
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TW103102754A 2008-12-09 2009-12-07 類鐸受體的調節劑 TWI480268B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12106108P 2008-12-09 2008-12-09
US17040409P 2009-04-17 2009-04-17
US22438609P 2009-07-09 2009-07-09
US22737809P 2009-07-21 2009-07-21
US24263509P 2009-09-15 2009-09-15

Publications (2)

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TW201441204A TW201441204A (zh) 2014-11-01
TWI480268B true TWI480268B (zh) 2015-04-11

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Family Applications (5)

Application Number Title Priority Date Filing Date
TW104102090A TWI534136B (zh) 2008-12-09 2009-12-07 用於製備可用作類鐸受體調節劑之化合物的中間體化合物
TW103102754A TWI480268B (zh) 2008-12-09 2009-12-07 類鐸受體的調節劑
TW105125448A TW201639852A (zh) 2008-12-09 2009-12-07 用於製備可用作類鐸受體調節劑之化合物的中間體化合物
TW105106322A TWI557117B (zh) 2008-12-09 2009-12-07 用於製備可用作類鐸受體調節劑之化合物的中間體化合物
TW98141711A TWI432436B (zh) 2008-12-09 2009-12-07 類鐸受體的調節劑

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TW104102090A TWI534136B (zh) 2008-12-09 2009-12-07 用於製備可用作類鐸受體調節劑之化合物的中間體化合物

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Application Number Title Priority Date Filing Date
TW105125448A TW201639852A (zh) 2008-12-09 2009-12-07 用於製備可用作類鐸受體調節劑之化合物的中間體化合物
TW105106322A TWI557117B (zh) 2008-12-09 2009-12-07 用於製備可用作類鐸受體調節劑之化合物的中間體化合物
TW98141711A TWI432436B (zh) 2008-12-09 2009-12-07 類鐸受體的調節劑

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US (8) US8367670B2 (es)
EP (3) EP2818469B1 (es)
JP (3) JP5600116B2 (es)
KR (2) KR101787309B1 (es)
CN (2) CN102272134B (es)
AP (1) AP2011005745A0 (es)
AR (1) AR074506A1 (es)
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