HK1161880A1 - Modulators of toll-like receptors - Google Patents

Modulators of toll-like receptors

Info

Publication number
HK1161880A1
HK1161880A1 HK12102422.0A HK12102422A HK1161880A1 HK 1161880 A1 HK1161880 A1 HK 1161880A1 HK 12102422 A HK12102422 A HK 12102422A HK 1161880 A1 HK1161880 A1 HK 1161880A1
Authority
HK
Hong Kong
Prior art keywords
toll
modulators
receptors
Prior art date
Application number
HK12102422.0A
Other languages
English (en)
Chinese (zh)
Inventor
Manoj C Desai
Randall L Halcomb
Paul Hrvatin
Hon Chung Hui
Ryan Mc Fadden
Paul A Roethle
Hong Yang
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41621203&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1161880(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of HK1161880A1 publication Critical patent/HK1161880A1/xx

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/527—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim spiro-condensed
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/10—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with an aromatic or hetero-aromatic ring directly attached in position 2
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
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    • C07D487/04—Ortho-condensed systems
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
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HK12102422.0A 2008-12-09 2012-03-09 Modulators of toll-like receptors HK1161880A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US12106108P 2008-12-09 2008-12-09
US17040409P 2009-04-17 2009-04-17
US22438609P 2009-07-09 2009-07-09
US22737809P 2009-07-21 2009-07-21
US24263509P 2009-09-15 2009-09-15
PCT/US2009/067002 WO2010077613A1 (en) 2008-12-09 2009-12-07 Modulators of toll-like receptors

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HK1161880A1 true HK1161880A1 (en) 2012-08-10

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HK12102422.0A HK1161880A1 (en) 2008-12-09 2012-03-09 Modulators of toll-like receptors
HK15106200.6A HK1205737A1 (en) 2008-12-09 2015-06-30 Intermediates for the preparation of modulators of toll-like receptors

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US (8) US8367670B2 (xx)
EP (3) EP2818469B1 (xx)
JP (3) JP5600116B2 (xx)
KR (2) KR101787309B1 (xx)
CN (2) CN102272134B (xx)
AP (1) AP2011005745A0 (xx)
AR (1) AR074506A1 (xx)
AU (1) AU2009333559B2 (xx)
BR (1) BRPI0923305B1 (xx)
CA (1) CA2745295C (xx)
CL (1) CL2011001392A1 (xx)
CO (1) CO6362010A2 (xx)
CY (1) CY1115176T1 (xx)
DK (1) DK2364314T3 (xx)
EA (3) EA021377B9 (xx)
EC (2) ECSP11011189A (xx)
ES (2) ES2467108T3 (xx)
HK (2) HK1161880A1 (xx)
HR (1) HRP20140539T1 (xx)
IL (2) IL213101A (xx)
MX (1) MX2011006152A (xx)
NZ (2) NZ612380A (xx)
PE (1) PE20120106A1 (xx)
PL (1) PL2364314T3 (xx)
PT (2) PT2364314E (xx)
RS (1) RS53347B (xx)
SG (1) SG172060A1 (xx)
SI (1) SI2364314T1 (xx)
SM (1) SMT201400083B (xx)
TW (5) TWI534136B (xx)
UY (1) UY32306A (xx)
WO (1) WO2010077613A1 (xx)
ZA (1) ZA201104998B (xx)

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TW201639852A (zh) 2016-11-16
JP6104432B2 (ja) 2017-03-29
TWI557117B (zh) 2016-11-11
US20180085370A1 (en) 2018-03-29
AR074506A1 (es) 2011-01-19
BRPI0923305A2 (pt) 2016-12-13
CN103497192A (zh) 2014-01-08
SI2364314T1 (sl) 2014-07-31
TWI480268B (zh) 2015-04-11
EA201491607A1 (ru) 2015-07-30
HK1205737A1 (en) 2015-12-24
KR101787309B1 (ko) 2017-10-18
ES2467108T3 (es) 2014-06-11
IL213101A (en) 2014-12-31
PE20120106A1 (es) 2012-02-20
US8367670B2 (en) 2013-02-05
NZ612380A (en) 2015-01-30
EA201692167A1 (ru) 2017-07-31
US9127006B2 (en) 2015-09-08
IL236272A0 (en) 2015-01-29
EP2364314A1 (en) 2011-09-14
EA021377B1 (ru) 2015-06-30
ES2623794T3 (es) 2017-07-12
CA2745295A1 (en) 2010-07-08
AU2009333559A1 (en) 2011-07-14
US20190321366A1 (en) 2019-10-24
TWI432436B (zh) 2014-04-01
EA201190021A1 (ru) 2012-04-30
EP3210982A1 (en) 2017-08-30
JP5600116B2 (ja) 2014-10-01
US11110091B2 (en) 2021-09-07
TW201623255A (zh) 2016-07-01

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