JP5133416B2 - １’，３’−二置換−４−フェニル−３，４，５，６−テトラヒドロ−２ｈ，１’ｈ−［１，４’］ビピリジニル−２’−オン - Google Patents

１’，３’−二置換−４−フェニル−３，４，５，６−テトラヒドロ−２ｈ，１’ｈ−［１，４’］ビピリジニル−２’−オン Download PDF

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JP5133416B2
JP5133416B2 JP2010524405A JP2010524405A JP5133416B2 JP 5133416 B2 JP5133416 B2 JP 5133416B2 JP 2010524405 A JP2010524405 A JP 2010524405A JP 2010524405 A JP2010524405 A JP 2010524405A JP 5133416 B2 JP5133416 B2 JP 5133416B2
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JP2010539121A (ja
JP2010539121A5 (https=
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ホセ， マリア シドゥ−ヌネズ，
アンドレ， アヴェリノ トラバンコ−スアレス，
グレゴール， ジェームス マクドナルド，
ギラーム， アルバート， ジャックス ドゥベーイ，
ロバート， ヨハネス リッツェンス，
テリー， パトリック フィン，
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オルソー−マクニール−ジャンセン ファーマシューティカルズ， インコーポレイテッド．
アデックス ファーマ エス エー
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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JP2010524405A 2007-09-14 2008-09-12 １’，３’−二置換−４−フェニル−３，４，５，６−テトラヒドロ−２ｈ，１’ｈ−［１，４’］ビピリジニル−２’−オン Active JP5133416B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07116390.1 2007-09-14
EP07116390 2007-09-14
PCT/EP2008/007551 WO2009033704A1 (en) 2007-09-14 2008-09-12 1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h, 1'h-[1, 4'] bipyridinyl-2'-ones

Publications (3)

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JP2010539121A JP2010539121A (ja) 2010-12-16
JP2010539121A5 JP2010539121A5 (https=) 2012-11-01
JP5133416B2 true JP5133416B2 (ja) 2013-01-30

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US (6) US9114138B2 (https=)
EP (1) EP2203439B1 (https=)
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KR (2) KR101520086B1 (https=)
CN (2) CN101801951B (https=)
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AT (1) ATE496906T1 (https=)
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GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
TWI417095B (zh) 2006-03-15 2013-12-01 Janssen Pharmaceuticals Inc １，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
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JP2010539121A (ja) 2010-12-16
AU2008297878A1 (en) 2009-03-19
BRPI0816767A2 (pt) 2017-05-16
IL204032A (en) 2013-11-28
AU2008297878B2 (en) 2011-07-07
US20130197019A1 (en) 2013-08-01
PL2203439T3 (pl) 2011-06-30
HRP20110278T1 (hr) 2011-05-31
EA017648B1 (ru) 2013-02-28
CL2008002745A1 (es) 2009-05-22
TW201412313A (zh) 2014-04-01
DE602008004794D1 (de) 2011-03-10
IL229304A0 (en) 2013-12-31
RS51660B (sr) 2011-10-31
US9114138B2 (en) 2015-08-25
WO2009033704A1 (en) 2009-03-19
AR068511A1 (es) 2009-11-18
TWI475995B (zh) 2015-03-11
EP2203439B1 (en) 2011-01-26
ATE496906T1 (de) 2011-02-15
CA2696948A1 (en) 2009-03-19
HK1143820A1 (en) 2011-01-14
KR20140034904A (ko) 2014-03-20
TW200927108A (en) 2009-07-01
ES2356032T3 (es) 2011-04-04
CN103342695B (zh) 2015-04-22
UA100126C2 (en) 2012-11-26
CN101801951B (zh) 2013-11-13
EP2203439A1 (en) 2010-07-07
MX2010002536A (es) 2010-08-10
US20100240688A1 (en) 2010-09-23
CN103342695A (zh) 2013-10-09
CA2696948C (en) 2013-04-30
KR101520086B1 (ko) 2015-05-14
TWI445532B (zh) 2014-07-21
US20220000856A1 (en) 2022-01-06
ZA201001151B (en) 2011-04-28
US20200038391A1 (en) 2020-02-06
MY152078A (en) 2014-08-15
US11071729B2 (en) 2021-07-27
IL229304A (en) 2015-08-31
US20150336930A1 (en) 2015-11-26
KR101533440B1 (ko) 2015-07-03
DK2203439T3 (da) 2011-04-18
BRPI0816767B1 (pt) 2021-03-09

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