ATE446294T1 - N4-phenyl-chinazolin-4-aminderivate und verwandte verbindungen als inhibitoren der erbb-typ-i- rezeptortyrosinkinase zur behandlung hyperproliferativer krankheiten - Google Patents

N4-phenyl-chinazolin-4-aminderivate und verwandte verbindungen als inhibitoren der erbb-typ-i- rezeptortyrosinkinase zur behandlung hyperproliferativer krankheiten

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Publication number
ATE446294T1
ATE446294T1 AT06837728T AT06837728T ATE446294T1 AT E446294 T1 ATE446294 T1 AT E446294T1 AT 06837728 T AT06837728 T AT 06837728T AT 06837728 T AT06837728 T AT 06837728T AT E446294 T1 ATE446294 T1 AT E446294T1
Authority
AT
Austria
Prior art keywords
treatment
tyrosine kinase
kinase inhibitors
quinazoline
receptor tyrosine
Prior art date
Application number
AT06837728T
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English (en)
Inventor
Joseph Lyssikatos
Fredrik Marmsater
Qian Zhao
Julie Greschuk
Original Assignee
Array Biopharma Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38022019&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE446294(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
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Publication of ATE446294T1 publication Critical patent/ATE446294T1/de

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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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AT06837728T 2005-11-15 2006-11-15 N4-phenyl-chinazolin-4-aminderivate und verwandte verbindungen als inhibitoren der erbb-typ-i- rezeptortyrosinkinase zur behandlung hyperproliferativer krankheiten ATE446294T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73628905P 2005-11-15 2005-11-15
US81701906P 2006-06-28 2006-06-28
PCT/US2006/044431 WO2007059257A2 (en) 2005-11-15 2006-11-15 N4-phenyl-quinaz0line-4 -amine derivatives and related compounds as erbb type i receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases

Publications (1)

Publication Number Publication Date
ATE446294T1 true ATE446294T1 (de) 2009-11-15

Family

ID=38022019

Family Applications (2)

Application Number Title Priority Date Filing Date
AT09157031T ATE507224T1 (de) 2005-11-15 2006-11-15 Verfahren und zwischenverbindungen zur herstellung von n4-phenyl-quinazolin-4-amin derivaten
AT06837728T ATE446294T1 (de) 2005-11-15 2006-11-15 N4-phenyl-chinazolin-4-aminderivate und verwandte verbindungen als inhibitoren der erbb-typ-i- rezeptortyrosinkinase zur behandlung hyperproliferativer krankheiten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT09157031T ATE507224T1 (de) 2005-11-15 2006-11-15 Verfahren und zwischenverbindungen zur herstellung von n4-phenyl-quinazolin-4-amin derivaten

Country Status (28)

Country Link
US (6) US8648087B2 (de)
EP (2) EP2090575B1 (de)
JP (2) JP5134548B2 (de)
KR (1) KR101086967B1 (de)
CN (2) CN102887891B (de)
AT (2) ATE507224T1 (de)
AU (2) AU2006315383B2 (de)
BR (2) BRPI0618668B1 (de)
CA (2) CA2755268C (de)
CY (3) CY1110583T1 (de)
DE (2) DE602006009968D1 (de)
DK (2) DK2090575T3 (de)
ES (2) ES2335535T3 (de)
FI (1) FIC20210022I1 (de)
FR (1) FR21C1031I2 (de)
HU (1) HUS2100028I1 (de)
IL (2) IL239149A (de)
LT (1) LTC1971601I2 (de)
LU (1) LUC00217I2 (de)
NL (1) NL301113I2 (de)
NO (1) NO342413B1 (de)
PL (2) PL2090575T3 (de)
PT (2) PT2090575E (de)
RU (2) RU2592703C9 (de)
SG (1) SG152230A1 (de)
SI (2) SI1971601T1 (de)
WO (1) WO2007059257A2 (de)
ZA (1) ZA200804498B (de)

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NZ545459A (en) 2003-08-14 2009-12-24 Array Biopharma Inc Quinazoline analogs as receptor tyrosine kinase inhibitors
GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
DE602006009968D1 (de) 2005-11-15 2009-12-03 Array Biopharma Inc N4-phenyl-chinazolin-4-aminderivate und verwandte verbindungen als inhibitoren der erbb-typ-i-rezeptortyrosinkinase zur behandlung hyperproliferativer krankheiten
TWI417095B (zh) 2006-03-15 2013-12-01 Janssen Pharmaceuticals Inc １，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
AU2007296744A1 (en) * 2006-09-11 2008-03-20 Curis, Inc. Multi-functional small molecules as anti-proliferative agents
EP2061773A4 (de) * 2006-09-11 2011-01-19 Curis Inc Chinazolin-basierte egfr-hemmer mit einem zinkbindenden teil
US7547781B2 (en) 2006-09-11 2009-06-16 Curis, Inc. Quinazoline based EGFR inhibitors containing a zinc binding moiety
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
CL2008001626A1 (es) * 2007-06-05 2009-06-05 Takeda Pharmaceuticals Co Compuestos derivados de heterociclos fusionados, agente farmaceutico que los comprende y su uso en la profilaxis y tratamiento del cancer.
JP5433579B2 (ja) 2007-09-14 2014-03-05 ジャンセン ファーマシューティカルズ， インコーポレイテッド． １，３−二置換−４−フェニル−１ｈ−ピリジン−２−オン
ATE516272T1 (de) 2007-09-14 2011-07-15 Ortho Mcneil Janssen Pharm 1,3-disubstituierte 4-(aryl-x-phenyl)-1h-pyridin- 2-one
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DE602006021645D1 (de) 2011-06-09
PL2090575T3 (pl) 2011-09-30
US20230142839A1 (en) 2023-05-11
US12171739B2 (en) 2024-12-24
BRPI0618668A2 (pt) 2011-09-06
IL248993A0 (en) 2017-01-31
NO20082598L (no) 2008-08-06
WO2007059257A3 (en) 2007-08-23
DK1971601T3 (da) 2010-02-08
ATE507224T1 (de) 2011-05-15
US20110034689A1 (en) 2011-02-10
US20140023643A1 (en) 2014-01-23
IL239149A (en) 2016-11-30
CY2021019I1 (el) 2021-10-15
EP1971601A2 (de) 2008-09-24
AU2010202330B2 (en) 2012-07-19
ES2364901T3 (es) 2011-09-16
CA2755268A1 (en) 2007-05-24
JP2009515988A (ja) 2009-04-16
AU2006315383A1 (en) 2007-05-24
EP2090575A1 (de) 2009-08-19
LTPA2021516I1 (de) 2021-08-10
ES2335535T3 (es) 2010-03-29
FIC20210022I1 (fi) 2021-07-09
WO2007059257A2 (en) 2007-05-24
RU2592703C9 (ru) 2016-10-20
SI1971601T1 (sl) 2010-03-31
NL301113I1 (nl) 2021-07-01
FR21C1031I2 (fr) 2022-07-15
CN102887891A (zh) 2013-01-23
BR122018075851B1 (pt) 2022-01-11
CY2021019I2 (el) 2021-12-31
US10780073B2 (en) 2020-09-22
EP1971601B1 (de) 2009-10-21
IL239149A0 (en) 2015-07-30
US20170252317A1 (en) 2017-09-07
RU2011122539A (ru) 2012-12-10
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PL1971601T3 (pl) 2010-03-31
US20180271824A1 (en) 2018-09-27

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