JP5006485B2 - Ｒｎａを切断するオリゴリボヌクレオチドおよびリボヌクレアーゼ - Google Patents

Ｒｎａを切断するオリゴリボヌクレオチドおよびリボヌクレアーゼ Download PDF

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JP5006485B2
JP5006485B2 JP53566397A JP53566397A JP5006485B2 JP 5006485 B2 JP5006485 B2 JP 5006485B2 JP 53566397 A JP53566397 A JP 53566397A JP 53566397 A JP53566397 A JP 53566397A JP 5006485 B2 JP5006485 B2 JP 5006485B2
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rna
nucleoside
segment
oligoribonucleotides
compound
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Expired - Lifetime
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Japanese (ja)
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JP2000510446A5 (cg-RX-API-DMAC10.html
JP2000510446A (ja
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クローケ，スタンレー・ティー
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Ionis Pharmaceuticals Inc
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Ionis Pharmaceuticals Inc
Isis Pharmaceuticals Inc
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP53566397A 1996-06-06 1997-06-06 Ｒｎａを切断するオリゴリボヌクレオチドおよびリボヌクレアーゼ Expired - Lifetime JP5006485B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/659,440 1996-06-06
US08/659,440 US5898031A (en) 1996-06-06 1996-06-06 Oligoribonucleotides for cleaving RNA
PCT/US1997/009963 WO1997046570A1 (en) 1996-06-06 1997-06-06 Oligoribonucleotides and ribonucleases for cleaving rna

Related Child Applications (1)

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JP2011017207A Division JP2011142911A (ja) 1996-06-06 2011-01-28 Ｒｎａを切断するオリゴリボヌクレオチドおよびリボヌクレアーゼ

Publications (3)

Publication Number Publication Date
JP2000510446A JP2000510446A (ja) 2000-08-15
JP2000510446A5 JP2000510446A5 (cg-RX-API-DMAC10.html) 2005-02-10
JP5006485B2 true JP5006485B2 (ja) 2012-08-22

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ID=24645410

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JP53566397A Expired - Lifetime JP5006485B2 (ja) 1996-06-06 1997-06-06 Ｒｎａを切断するオリゴリボヌクレオチドおよびリボヌクレアーゼ
JP2011017207A Pending JP2011142911A (ja) 1996-06-06 2011-01-28 Ｒｎａを切断するオリゴリボヌクレオチドおよびリボヌクレアーゼ

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JP2011017207A Pending JP2011142911A (ja) 1996-06-06 2011-01-28 Ｒｎａを切断するオリゴリボヌクレオチドおよびリボヌクレアーゼ

Country Status (7)

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US (10) US5898031A (cg-RX-API-DMAC10.html)
EP (4) EP1600506A3 (cg-RX-API-DMAC10.html)
JP (2) JP5006485B2 (cg-RX-API-DMAC10.html)
AT (1) ATE292141T1 (cg-RX-API-DMAC10.html)
AU (1) AU3383297A (cg-RX-API-DMAC10.html)
DE (1) DE69732911T2 (cg-RX-API-DMAC10.html)
WO (1) WO1997046570A1 (cg-RX-API-DMAC10.html)

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US20040142895A1 (en) * 1995-10-26 2004-07-22 Sirna Therapeutics, Inc. Nucleic acid-based modulation of gene expression in the vascular endothelial growth factor pathway
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