|
EP0642589A4
(en)
*
|
1992-05-11 |
1997-05-21 |
Ribozyme Pharm Inc |
METHOD AND REAGENT TO INHIBIT VIRAL REPLICATION.
|
|
US20030206887A1
(en)
*
|
1992-05-14 |
2003-11-06 |
David Morrissey |
RNA interference mediated inhibition of hepatitis B virus (HBV) using short interfering nucleic acid (siNA)
|
|
US5639647A
(en)
*
|
1994-03-29 |
1997-06-17 |
Ribozyme Pharmaceuticals, Inc. |
2'-deoxy-2'alkylnucleotide containing nucleic acid
|
|
US5898031A
(en)
|
1996-06-06 |
1999-04-27 |
Isis Pharmaceuticals, Inc. |
Oligoribonucleotides for cleaving RNA
|
|
US9096636B2
(en)
|
1996-06-06 |
2015-08-04 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
|
US7812149B2
(en)
|
1996-06-06 |
2010-10-12 |
Isis Pharmaceuticals, Inc. |
2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
|
|
US7994295B2
(en)
*
|
1997-12-22 |
2011-08-09 |
The University Of Tennessee Research Corporation |
Recombinant viruses comprising the membrane-proximal domain of VSV G protein
|
|
US6506559B1
(en)
|
1997-12-23 |
2003-01-14 |
Carnegie Institute Of Washington |
Genetic inhibition by double-stranded RNA
|
|
KR20010042069A
(ko)
|
1998-03-20 |
2001-05-25 |
베니텍 오스트레일리아 리미티드 |
유전자 발현 조절방법
|
|
AUPP249298A0
(en)
*
|
1998-03-20 |
1998-04-23 |
Ag-Gene Australia Limited |
Synthetic genes and genetic constructs comprising same I
|
|
US20030228597A1
(en)
*
|
1998-04-13 |
2003-12-11 |
Cowsert Lex M. |
Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation
|
|
AU3751299A
(en)
*
|
1998-04-20 |
1999-11-08 |
Ribozyme Pharmaceuticals, Inc. |
Nucleic acid molecules with novel chemical compositions capable of modulating gene expression
|
|
US20040242521A1
(en)
*
|
1999-10-25 |
2004-12-02 |
Board Of Regents, The University Of Texas System |
Thio-siRNA aptamers
|
|
US20060172925A1
(en)
*
|
1998-10-26 |
2006-08-03 |
Board Of Regents, The University Of Texas System |
Thio-siRNA aptamers
|
|
EP2314700A1
(en)
*
|
1999-01-28 |
2011-04-27 |
Medical College of Georgia Research Institute, Inc |
Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA
|
|
DE19956568A1
(de)
*
|
1999-01-30 |
2000-08-17 |
Roland Kreutzer |
Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
|
|
US6987025B1
(en)
|
1999-02-11 |
2006-01-17 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Dwf4 polynucleotides, polypeptides and uses thereof
|
|
US7601494B2
(en)
|
1999-03-17 |
2009-10-13 |
The University Of North Carolina At Chapel Hill |
Method of screening candidate compounds for susceptibility to biliary excretion
|
|
BR0009884A
(pt)
*
|
1999-04-21 |
2002-01-08 |
American Home Prod |
Processos e composições para a inibição da função das sequências de polinucleotìdeos
|
|
US20040138168A1
(en)
*
|
1999-04-21 |
2004-07-15 |
Wyeth |
Methods and compositions for inhibiting the function of polynucleotide sequences
|
|
US20040002153A1
(en)
*
|
1999-07-21 |
2004-01-01 |
Monia Brett P. |
Modulation of PTEN expression via oligomeric compounds
|
|
US6423885B1
(en)
*
|
1999-08-13 |
2002-07-23 |
Commonwealth Scientific And Industrial Research Organization (Csiro) |
Methods for obtaining modified phenotypes in plant cells
|
|
GB9925459D0
(en)
*
|
1999-10-27 |
1999-12-29 |
Plant Bioscience Ltd |
Gene silencing
|
|
US7829693B2
(en)
*
|
1999-11-24 |
2010-11-09 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a target gene
|
|
DE10100586C1
(de)
|
2001-01-09 |
2002-04-11 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines Ziegens
|
|
DE10160151A1
(de)
*
|
2001-01-09 |
2003-06-26 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines vorgegebenen Zielgens
|
|
US20050032733A1
(en)
*
|
2001-05-18 |
2005-02-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
|
|
US8202979B2
(en)
*
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
|
US20050020525A1
(en)
*
|
2002-02-20 |
2005-01-27 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US20080039414A1
(en)
*
|
2002-02-20 |
2008-02-14 |
Sima Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US20070026394A1
(en)
*
|
2000-02-11 |
2007-02-01 |
Lawrence Blatt |
Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies
|
|
US8273866B2
(en)
|
2002-02-20 |
2012-09-25 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA)
|
|
US20030084471A1
(en)
*
|
2000-03-16 |
2003-05-01 |
David Beach |
Methods and compositions for RNA interference
|
|
US8202846B2
(en)
|
2000-03-16 |
2012-06-19 |
Cold Spring Harbor Laboratory |
Methods and compositions for RNA interference
|
|
EP1272630A2
(en)
*
|
2000-03-16 |
2003-01-08 |
Genetica, Inc. |
Methods and compositions for rna interference
|
|
CA2403162A1
(en)
*
|
2000-03-17 |
2001-09-27 |
Benitec Australia Ltd. |
Genetic silencing
|
|
BRPI0117341B1
(pt)
*
|
2000-03-30 |
2016-06-21 |
Massachusetts Inst Technology |
método para avaliar um agente agindo em um produto de gene, método para avaliar se um produto de gene é um alvo adequado para descoberta de drogas e método para avaliar se um produto de gene é um alvo adequado para avaliar a habilidade de um agente agir no produto de gene
|
|
PT1309726E
(pt)
*
|
2000-03-30 |
2010-03-08 |
Whitehead Biomedical Inst |
Mediadores de interferência por rna específicos de sequência de rna
|
|
US7691991B2
(en)
|
2000-04-17 |
2010-04-06 |
Ceres, Inc. |
Sequence-determined DNA fragments encoding cytochrome P450 proteins
|
|
AU2001284160A1
(en)
*
|
2000-08-19 |
2002-03-04 |
Axordia Limited |
Modulation of stem cell differentiation
|
|
US20030190635A1
(en)
*
|
2002-02-20 |
2003-10-09 |
Mcswiggen James A. |
RNA interference mediated treatment of Alzheimer's disease using short interfering RNA
|
|
US20020165192A1
(en)
|
2000-09-19 |
2002-11-07 |
Kerr William G. |
Control of NK cell function and survival by modulation of ship activity
|
|
EP1666595A1
(en)
|
2000-10-26 |
2006-06-07 |
Beth Israel Deaconess Medical Center, Inc. |
GAB2 (P97) gene and methods of use thereof
|
|
AU2013201799B2
(en)
*
|
2000-12-01 |
2014-08-14 |
Europaisches Laboratorium Fur Molekularbiologie (Embl) |
Rna interference mediating small rna molecules
|
|
KR100909681B1
(ko)
|
2000-12-01 |
2009-07-29 |
막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. |
Rna 간섭을 매개하는 작은 rna 분자
|
|
US7385046B2
(en)
|
2001-01-03 |
2008-06-10 |
Ceres, Inc. |
Sequence-determined DNA fragments encoding ethylene responsive element binding proteins
|
|
US8546143B2
(en)
|
2001-01-09 |
2013-10-01 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a target gene
|
|
US7423142B2
(en)
*
|
2001-01-09 |
2008-09-09 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of anti-apoptotic genes
|
|
US7767802B2
(en)
|
2001-01-09 |
2010-08-03 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of anti-apoptotic genes
|
|
US20020132257A1
(en)
*
|
2001-01-31 |
2002-09-19 |
Tony Giordano |
Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
|
|
JP3765574B2
(ja)
*
|
2001-02-22 |
2006-04-12 |
三菱化学株式会社 |
逆向き反復配列を含む組み換え遺伝子及びその利用
|
|
US20050159378A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA)
|
|
US20050124566A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)
|
|
US20050159381A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of chromosome translocation gene expression using short interfering nucleic acid (siNA)
|
|
US20050196781A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of STAT3 gene expression using short interfering nucleic acid (siNA)
|
|
US7517864B2
(en)
|
2001-05-18 |
2009-04-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
US20050143333A1
(en)
*
|
2001-05-18 |
2005-06-30 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
|
|
US20050176666A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of GPRA and AAA1 gene expression using short interfering nucleic acid (siNA)
|
|
US20050136436A1
(en)
*
|
2001-05-18 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of G72 and D-amino acid oxidase (DAAO) gene expression using short interfering nucleic acid (siNA)
|
|
US20050176663A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sima Therapeutics, Inc. |
RNA interference mediated inhibition of protein tyrosine phosphatase type IVA (PRL3) gene expression using short interfering nucleic acid (siNA)
|
|
WO2004111237A1
(en)
*
|
2003-04-16 |
2004-12-23 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF PLATELET-DERIVED ENDOTHELIAL CELL GROWTH FACTOR (ECGF1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
US20050153914A1
(en)
*
|
2001-05-18 |
2005-07-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of MDR P-glycoprotein gene expression using short interfering nucleic acid (siNA)
|
|
US7109165B2
(en)
*
|
2001-05-18 |
2006-09-19 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
|
US20050176025A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)
|
|
US20050171040A1
(en)
*
|
2001-05-18 |
2005-08-04 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cholesteryl ester transfer protein (CEPT) gene expression using short interfering nucleic acid (siNA)
|
|
US20050277133A1
(en)
*
|
2001-05-18 |
2005-12-15 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)
|
|
US20050233344A1
(en)
*
|
2001-05-18 |
2005-10-20 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of platelet derived growth factor (PDGF) and platelet derived growth factor receptor (PDGFR) gene expression using short interfering nucleic acid (siNA)
|
|
US20070042983A1
(en)
*
|
2001-05-18 |
2007-02-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
|
US20050048529A1
(en)
*
|
2002-02-20 |
2005-03-03 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
|
|
US9994853B2
(en)
|
2001-05-18 |
2018-06-12 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
|
US20050222066A1
(en)
*
|
2001-05-18 |
2005-10-06 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
US20050119212A1
(en)
*
|
2001-05-18 |
2005-06-02 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of FAS and FASL gene expression using short interfering nucleic acid (siNA)
|
|
US20050137155A1
(en)
*
|
2001-05-18 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of Parkinson disease using short interfering nucleic acid (siNA)
|
|
US20080188430A1
(en)
*
|
2001-05-18 |
2008-08-07 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)
|
|
US20040019001A1
(en)
*
|
2002-02-20 |
2004-01-29 |
Mcswiggen James A. |
RNA interference mediated inhibition of protein typrosine phosphatase-1B (PTP-1B) gene expression using short interfering RNA
|
|
WO2005078097A2
(en)
|
2004-02-10 |
2005-08-25 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING MULTIFUNCTIONAL SHORT INTERFERING NUCLEIC ACID (Multifunctional siNA)
|
|
US20040198682A1
(en)
*
|
2001-11-30 |
2004-10-07 |
Mcswiggen James |
RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (siNA)
|
|
US20030175950A1
(en)
*
|
2001-05-29 |
2003-09-18 |
Mcswiggen James A. |
RNA interference mediated inhibition of HIV gene expression using short interfering RNA
|
|
US20050261219A1
(en)
*
|
2001-05-18 |
2005-11-24 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA)
|
|
US20050158735A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of proliferating cell nuclear antigen (PCNA) gene expression using short interfering nucleic acid (siNA)
|
|
US20050124569A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)
|
|
US20050191618A1
(en)
*
|
2001-05-18 |
2005-09-01 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of human immunodeficiency virus (HIV) gene expression using short interfering nucleic acid (siNA)
|
|
US20050054596A1
(en)
*
|
2001-11-30 |
2005-03-10 |
Mcswiggen James |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
AU2004266311B2
(en)
*
|
2001-05-18 |
2009-07-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US20060217331A1
(en)
*
|
2001-05-18 |
2006-09-28 |
Sirna Therapeutics, Inc. |
Chemically modified double stranded nucleic acid molecules that mediate RNA interference
|
|
US20080161256A1
(en)
*
|
2001-05-18 |
2008-07-03 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
|
US20060142225A1
(en)
*
|
2001-05-18 |
2006-06-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cyclin dependent kinase-2 (CDK2) gene expression using short interfering nucleic acid (siNA)
|
|
US20050159380A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of angiopoietin gene expression using short interfering nucleic acid (siNA)
|
|
US20050196767A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acis (siNA)
|
|
US20090299045A1
(en)
*
|
2001-05-18 |
2009-12-03 |
Sirna Therapeutics, Inc. |
RNA Interference Mediated Inhibition Of Interleukin and Interleukin Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
|
US20050267058A1
(en)
*
|
2001-05-18 |
2005-12-01 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (sINA)
|
|
US20070093437A1
(en)
*
|
2001-05-18 |
2007-04-26 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of xiap gene expression using short interfering nucleic acid (sina)
|
|
US20050209180A1
(en)
*
|
2001-05-18 |
2005-09-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hepatitis C virus (HCV) expression using short interfering nucleic acid (siNA)
|
|
US20060211642A1
(en)
*
|
2001-05-18 |
2006-09-21 |
Sirna Therapeutics, Inc. |
RNA inteference mediated inhibition of hepatitis C virus (HVC) gene expression using short interfering nucleic acid (siNA)
|
|
US20060241075A1
(en)
*
|
2001-05-18 |
2006-10-26 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of desmoglein gene expression using short interfering nucleic acid (siNA)
|
|
US20050182007A1
(en)
*
|
2001-05-18 |
2005-08-18 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
|
|
US20070270579A1
(en)
*
|
2001-05-18 |
2007-11-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
|
US20050196765A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of checkpoint Kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)
|
|
US20050159382A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)
|
|
US20050164224A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)
|
|
US20050148530A1
(en)
|
2002-02-20 |
2005-07-07 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
US20050159379A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc |
RNA interference mediated inhibition of gastric inhibitory polypeptide (GIP) and gastric inhibitory polypeptide receptor (GIPR) gene expression using short interfering nucleic acid (siNA)
|
|
US20050164968A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of ADAM33 gene expression using short interfering nucleic acid (siNA)
|
|
US20050287128A1
(en)
*
|
2001-05-18 |
2005-12-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of TGF-beta and TGF-beta receptor gene expression using short interfering nucleic acid (siNA)
|
|
US20050282188A1
(en)
*
|
2001-05-18 |
2005-12-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
|
US20050079610A1
(en)
*
|
2001-05-18 |
2005-04-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA)
|
|
US20050203040A1
(en)
*
|
2001-05-18 |
2005-09-15 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)
|
|
US20050164967A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA)
|
|
US20050288242A1
(en)
*
|
2001-05-18 |
2005-12-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)
|
|
US20050187174A1
(en)
*
|
2001-05-18 |
2005-08-25 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
|
|
EP1390472A4
(en)
*
|
2001-05-29 |
2004-11-17 |
Sirna Therapeutics Inc |
NUCLEIC ACID TREATMENT OF DISEASES OR SIDES RELATED TO RAS, HER2 AND HIV LEVELS
|
|
WO2003001877A2
(en)
*
|
2001-06-26 |
2003-01-09 |
Gene Logic, Inc. |
Methods for the diagnosis and treatment of cardiac tissue rejection
|
|
IL159756A0
(en)
|
2001-07-12 |
2004-06-20 |
Univ Massachusetts |
IN VIVO PRODUCTION OF SMALL INTERFERING RNAs THAT MEDIATE GENE SILENCING
|
|
US10590418B2
(en)
*
|
2001-07-23 |
2020-03-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for RNAi mediated inhibition of gene expression in mammals
|
|
ES2546829T3
(es)
*
|
2001-07-23 |
2015-09-29 |
The Board Of Trustees Of The Leland Stanford Junior University |
Métodos y composiciones para la inhibición mediada por iARN de la expresión génica en mamíferos
|
|
US20030198627A1
(en)
*
|
2001-09-01 |
2003-10-23 |
Gert-Jan Arts |
siRNA knockout assay method and constructs
|
|
US7745418B2
(en)
*
|
2001-10-12 |
2010-06-29 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting viral replication
|
|
DE10163098B4
(de)
|
2001-10-12 |
2005-06-02 |
Alnylam Europe Ag |
Verfahren zur Hemmung der Replikation von Viren
|
|
CN1608133A
(zh)
*
|
2001-10-26 |
2005-04-20 |
里伯药品公司 |
双链核糖核酸用于治疗正(+)链rna病毒感染的用途
|
|
DE10230996A1
(de)
*
|
2001-10-26 |
2003-07-17 |
Ribopharma Ag |
Medikament zur Behandlung eines Pankreaskarzinoms
|
|
WO2003035870A1
(de)
*
|
2001-10-26 |
2003-05-01 |
Ribopharma Ag |
Medikament zur behandlung eines pankreaskarzinoms
|
|
JP2005512976A
(ja)
*
|
2001-10-26 |
2005-05-12 |
リボファーマ アーゲー |
Rna干渉により線維化疾患を処置するための医薬
|
|
DE10230997A1
(de)
*
|
2001-10-26 |
2003-07-17 |
Ribopharma Ag |
Medikament zur Erhöhung der Wirksamkeit eines Rezeptor-vermittelt Apoptose in Tumorzellen auslösenden Arzneimittels
|
|
US20040121348A1
(en)
*
|
2001-10-26 |
2004-06-24 |
Ribopharma Ag |
Compositions and methods for treating pancreatic cancer
|
|
US20040063654A1
(en)
*
|
2001-11-02 |
2004-04-01 |
Davis Mark E. |
Methods and compositions for therapeutic use of RNA interference
|
|
AU2002338926B2
(en)
|
2001-11-05 |
2007-05-24 |
Janssen Pharmaceutica N.V. |
Method for the in vitro synthesis of short double stranded RNAs
|
|
FR2832154B1
(fr)
*
|
2001-11-09 |
2007-03-16 |
Centre Nat Rech Scient |
Oligonucleotides inhibiteurs et leur utilisation pour reprimer specifiquement un gene
|
|
WO2003043580A2
(en)
*
|
2001-11-19 |
2003-05-30 |
Proteologics, Inc. |
Methods for identifying and validating potential drug targets
|
|
EP1445312B1
(en)
*
|
2001-11-21 |
2012-12-26 |
Astellas Pharma Inc. |
Method of inhibiting gene expression
|
|
US20040138163A1
(en)
*
|
2002-05-29 |
2004-07-15 |
Mcswiggen James |
RNA interference mediated inhibition of vascular edothelial growth factor and vascular edothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
US20050075304A1
(en)
*
|
2001-11-30 |
2005-04-07 |
Mcswiggen James |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
US7871619B2
(en)
|
2001-11-30 |
2011-01-18 |
Chemocentryx, Inc. |
Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
|
|
US20070203333A1
(en)
*
|
2001-11-30 |
2007-08-30 |
Mcswiggen James |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
US7294504B1
(en)
|
2001-12-27 |
2007-11-13 |
Allele Biotechnology & Pharmaceuticals, Inc. |
Methods and compositions for DNA mediated gene silencing
|
|
JP4491240B2
(ja)
|
2002-01-17 |
2010-06-30 |
ザ ユニバーシティ オブ ブリティッシュ コロンビア |
Igfbp−2およびigfbp−5を阻害する二重特異性アンチセンスオリゴヌクレオチド、並びにこれらの使用方法
|
|
DE10202419A1
(de)
*
|
2002-01-22 |
2003-08-07 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines durch eine Chromosomen-Aberration entstandenen Zielgens
|
|
US20060009409A1
(en)
*
|
2002-02-01 |
2006-01-12 |
Woolf Tod M |
Double-stranded oligonucleotides
|
|
WO2003064625A2
(en)
*
|
2002-02-01 |
2003-08-07 |
Sequitur, Inc. |
Oligonucleotide compositions with enhanced efficiency
|
|
EP1572902B1
(en)
*
|
2002-02-01 |
2014-06-11 |
Life Technologies Corporation |
HIGH POTENCY siRNAS FOR REDUCING THE EXPRESSION OF TARGET GENES
|
|
ATE407138T1
(de)
*
|
2002-02-14 |
2008-09-15 |
Hope City |
Verfahren zur herstellung interferierender rna- moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle
|
|
US9181551B2
(en)
|
2002-02-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US20050096284A1
(en)
*
|
2002-02-20 |
2005-05-05 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)
|
|
ATE519774T1
(de)
|
2002-02-20 |
2011-08-15 |
Sirna Therapeutics Inc |
Durch eine störung der rna vermittelte inhibierung der genexpression des hepatitis c virus (hcv) mit kurzer, störender nukleinsäure (short interfering nucleic acid, sina)
|
|
US8067575B2
(en)
*
|
2002-02-20 |
2011-11-29 |
Merck, Sharp & Dohme Corp. |
RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)
|
|
AU2003207708A1
(en)
|
2002-02-20 |
2003-09-09 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of map kinase genes
|
|
US20090099117A1
(en)
*
|
2002-02-20 |
2009-04-16 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF MYOSTATIN GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
WO2003106476A1
(en)
*
|
2002-02-20 |
2003-12-24 |
Sirna Therapeutics, Inc |
Nucleic acid mediated inhibition of enterococcus infection and cytolysin toxin activity
|
|
US9657294B2
(en)
|
2002-02-20 |
2017-05-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US20050004008A1
(en)
*
|
2002-03-01 |
2005-01-06 |
Frackelton A. Raymond |
SHC proteins as therapeutic targets in proliferative diseases
|
|
AU2003218045A1
(en)
|
2002-03-11 |
2003-09-29 |
Ortho Mcneil Pharmaceutical, Inc |
Methods for shp1 mediated neuroprotection
|
|
US20030180712A1
(en)
|
2002-03-20 |
2003-09-25 |
Biostratum Ab |
Inhibition of the beta3 subunit of L-type Ca2+ channels
|
|
WO2003079757A2
(en)
*
|
2002-03-20 |
2003-10-02 |
Massachusetts Institute Of Technology |
Hiv therapeutic
|
|
US7357928B2
(en)
|
2002-04-08 |
2008-04-15 |
University Of Louisville Research Foundation, Inc. |
Method for the diagnosis and prognosis of malignant diseases
|
|
US7541150B2
(en)
|
2002-04-08 |
2009-06-02 |
University Of Louisville Research Foundation, Inc |
Method for the diagnosis and prognosis of malignant diseases
|
|
CA2482904A1
(en)
*
|
2002-04-18 |
2003-10-23 |
Lynkeus Biotech Gmbh |
Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification
|
|
US20040180438A1
(en)
|
2002-04-26 |
2004-09-16 |
Pachuk Catherine J. |
Methods and compositions for silencing genes without inducing toxicity
|
|
WO2003093430A2
(en)
*
|
2002-05-03 |
2003-11-13 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for use in preparing sirnas
|
|
WO2003093441A2
(en)
|
2002-05-03 |
2003-11-13 |
Duke University |
A method of regulating gene expression
|
|
AU2003239897A1
(en)
|
2002-05-23 |
2003-12-12 |
Ceptyr, Inc. |
Modulation of ptp1b signal transduction by rna interference
|
|
WO2003099298A1
(en)
*
|
2002-05-24 |
2003-12-04 |
Max-Planck Gesellschaft zur Förderung der Wissenschaften e.V. |
Rna interference mediating small rna molecules
|
|
US20100075423A1
(en)
*
|
2002-06-12 |
2010-03-25 |
Life Technologies Corporation |
Methods and compositions relating to polypeptides with rnase iii domains that mediate rna interference
|
|
US20040248094A1
(en)
*
|
2002-06-12 |
2004-12-09 |
Ford Lance P. |
Methods and compositions relating to labeled RNA molecules that reduce gene expression
|
|
WO2003106617A2
(en)
*
|
2002-06-12 |
2003-12-24 |
Tel Aviv Medical Center Research Development Fund |
Oligonucleotides antibodies and kits including same for treating prostate cancer and determining predisposition thereto
|
|
AU2003243541A1
(en)
*
|
2002-06-12 |
2003-12-31 |
Ambion, Inc. |
Methods and compositions relating to labeled rna molecules that reduce gene expression
|
|
WO2004001045A1
(en)
*
|
2002-06-20 |
2003-12-31 |
Dsm Ip Assets B.V. |
Inhibition of nuclear receptors
|
|
WO2004001013A2
(en)
*
|
2002-06-24 |
2003-12-31 |
Baylor College Of Medicine |
Inhibition of gene expression in vertebrates using double-stranded rna (rnai)
|
|
EP2267117A3
(en)
|
2002-06-27 |
2011-07-13 |
Verva Pharmaceuticals Pty Ltd |
Differentiation modulating agents and uses therefor
|
|
DE60334618D1
(de)
|
2002-06-28 |
2010-12-02 |
Protiva Biotherapeutics Inc |
Verfahren und vorrichtung zur herstellung von liposomen
|
|
DE10229872A1
(de)
*
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immunstimulation durch chemisch modifizierte RNA
|
|
DK2308507T3
(da)
|
2002-07-19 |
2015-04-20 |
Beth Israel Hospital |
Fremgangsmåder til behandling af præeklampsi
|
|
US7435419B2
(en)
|
2002-07-19 |
2008-10-14 |
Beth Israel Deaconess Medical Center |
Methods of diagnosing and treating pre-eclampsia or eclampsia
|
|
US7148342B2
(en)
*
|
2002-07-24 |
2006-12-12 |
The Trustees Of The University Of Pennyslvania |
Compositions and methods for sirna inhibition of angiogenesis
|
|
US7399851B2
(en)
|
2002-07-25 |
2008-07-15 |
Dana Farber Cancer Institute, Inc. |
Composition and method for imaging cells
|
|
AU2003261231A1
(en)
*
|
2002-07-26 |
2004-02-16 |
Chiron Corporation |
Modified small interfering rna molecules and methods of use
|
|
US20040023390A1
(en)
*
|
2002-08-05 |
2004-02-05 |
Davidson Beverly L. |
SiRNA-mediated gene silencing with viral vectors
|
|
BRPI0313202A8
(pt)
|
2002-08-05 |
2016-08-16 |
Atugen Ag |
Formas adicionais para interferir com as moléculas de rna
|
|
US20040241854A1
(en)
|
2002-08-05 |
2004-12-02 |
Davidson Beverly L. |
siRNA-mediated gene silencing
|
|
US20050106731A1
(en)
*
|
2002-08-05 |
2005-05-19 |
Davidson Beverly L. |
siRNA-mediated gene silencing with viral vectors
|
|
US20050042646A1
(en)
*
|
2002-08-05 |
2005-02-24 |
Davidson Beverly L. |
RNA interference suppresion of neurodegenerative diseases and methods of use thereof
|
|
HUE038749T2
(hu)
*
|
2002-08-05 |
2018-11-28 |
Silence Therapeutics Gmbh |
Interferáló RNS molekulák további új formái
|
|
DK1389637T3
(da)
*
|
2002-08-05 |
2012-09-03 |
Silence Therapeutics Ag |
Interfererende RNA-molekyler med stumpe ender
|
|
US20080176812A1
(en)
*
|
2002-08-05 |
2008-07-24 |
Davidson Beverly L |
Allele-specific silencing of disease genes
|
|
US20050255086A1
(en)
*
|
2002-08-05 |
2005-11-17 |
Davidson Beverly L |
Nucleic acid silencing of Huntington's Disease gene
|
|
US20080274989A1
(en)
*
|
2002-08-05 |
2008-11-06 |
University Of Iowa Research Foundation |
Rna Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof
|
|
US20060211637A1
(en)
*
|
2002-08-06 |
2006-09-21 |
Intradigm Corporation |
Methods of down regulating target gene expression in vivo by introduction of interfering rna
|
|
WO2004014933A1
(en)
|
2002-08-07 |
2004-02-19 |
University Of Massachusetts |
Compositions for rna interference and methods of use thereof
|
|
US20040029275A1
(en)
*
|
2002-08-10 |
2004-02-12 |
David Brown |
Methods and compositions for reducing target gene expression using cocktails of siRNAs or constructs expressing siRNAs
|
|
DE60328214D1
(de)
*
|
2002-08-12 |
2009-08-13 |
New England Biolabs Inc |
Verfahren und zusammensetzungen in verbindung mit gen-silencing
|
|
EP1393742A1
(en)
|
2002-08-14 |
2004-03-03 |
atugen AG |
Use of protein kinase N beta
|
|
DK1536827T3
(da)
|
2002-08-14 |
2009-04-20 |
Silence Therapeutics Ag |
Anvendelse af proteinkinase N-beta
|
|
EP1532249A2
(en)
|
2002-08-21 |
2005-05-25 |
The University of British Columbia |
Rnai probes targeting cancer-related proteins
|
|
US7923547B2
(en)
|
2002-09-05 |
2011-04-12 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
WO2004037977A2
(en)
|
2002-09-05 |
2004-05-06 |
California Institute Of Thechnology |
Use of chimeric nucleases to stimulate gene targeting
|
|
US7655772B2
(en)
|
2002-09-06 |
2010-02-02 |
University Of South Florida |
Materials and methods for treatment of allergic diseases
|
|
US20050272650A1
(en)
|
2004-02-17 |
2005-12-08 |
Mohapatra Shyam S |
Materials and methods for treatment of inflammatory and cell proliferation disorders
|
|
US20080260744A1
(en)
|
2002-09-09 |
2008-10-23 |
Omeros Corporation |
G protein coupled receptors and uses thereof
|
|
US20040053289A1
(en)
*
|
2002-09-09 |
2004-03-18 |
The Regents Of The University Of California |
Short interfering nucleic acid hybrids and methods thereof
|
|
AU2003267785C1
(en)
|
2002-09-13 |
2009-12-24 |
Replicor, Inc. |
Non-sequence complementary antiviral oligonucleotides
|
|
US20090217404A1
(en)
*
|
2002-09-27 |
2009-08-27 |
Lowe Scott W |
Cell-based RNA interference and related methods and compositions
|
|
KR20050084607A
(ko)
*
|
2002-09-28 |
2005-08-26 |
매사추세츠 인스티튜트 오브 테크놀로지 |
인플루엔자 치료제
|
|
US20040242518A1
(en)
*
|
2002-09-28 |
2004-12-02 |
Massachusetts Institute Of Technology |
Influenza therapeutic
|
|
US9453251B2
(en)
|
2002-10-08 |
2016-09-27 |
Pfenex Inc. |
Expression of mammalian proteins in Pseudomonas fluorescens
|
|
CA2501752A1
(en)
|
2002-10-10 |
2004-04-22 |
Wyeth |
Compositions, organisms and methodologies employing a novel human kinase
|
|
US20040077082A1
(en)
*
|
2002-10-18 |
2004-04-22 |
Koehn Richard K. |
RNA-based inhibitory oligonucleotides
|
|
WO2004035615A2
(en)
|
2002-10-18 |
2004-04-29 |
Atugen Ag |
Factor involved in metastasis and uses thereof
|
|
CA2503491A1
(en)
|
2002-10-24 |
2004-05-06 |
Wyeth |
Calcineurin-like human phosphoesterase
|
|
US20070059692A1
(en)
*
|
2002-10-28 |
2007-03-15 |
Xiaolian Gao |
Array oligomer synthesis and use
|
|
MXPA05004722A
(es)
|
2002-11-01 |
2005-08-03 |
Univ Pennsylvania |
Composiciones y metodos para la inhibicion del factor inducible por hipoxia 1 alfa con acido ribonucleico corto de interferencia.
|
|
US7892793B2
(en)
*
|
2002-11-04 |
2011-02-22 |
University Of Massachusetts |
Allele-specific RNA interference
|
|
EP1562971B1
(en)
|
2002-11-05 |
2014-02-12 |
Isis Pharmaceuticals, Inc. |
Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation
|
|
WO2004044138A2
(en)
|
2002-11-05 |
2004-05-27 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
|
US9150605B2
(en)
|
2002-11-05 |
2015-10-06 |
Isis Pharmaceuticals, Inc. |
Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
|
|
US9827263B2
(en)
|
2002-11-05 |
2017-11-28 |
Ionis Pharmaceuticals, Inc. |
2′-methoxy substituted oligomeric compounds and compositions for use in gene modulations
|
|
AU2003295387A1
(en)
|
2002-11-05 |
2004-06-03 |
Isis Parmaceuticals, Inc. |
Modified oligonucleotides for use in rna interference
|
|
US9150606B2
(en)
|
2002-11-05 |
2015-10-06 |
Isis Pharmaceuticals, Inc. |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
|
|
CN1498964A
(zh)
*
|
2002-11-07 |
2004-05-26 |
本元正阳基因技术股份有限公司 |
可诱导RNAi途径的用于基因治疗的系列重组腺相关病毒
|
|
US7977471B2
(en)
*
|
2002-11-14 |
2011-07-12 |
Dharmacon, Inc. |
siRNA targeting TNFα
|
|
US10011836B2
(en)
|
2002-11-14 |
2018-07-03 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
|
US8163896B1
(en)
|
2002-11-14 |
2012-04-24 |
Rosetta Genomics Ltd. |
Bioinformatically detectable group of novel regulatory genes and uses thereof
|
|
US7619081B2
(en)
*
|
2002-11-14 |
2009-11-17 |
Dharmacon, Inc. |
siRNA targeting coatomer protein complex, subunit beta 2 (COPB2)
|
|
US7951935B2
(en)
|
2002-11-14 |
2011-05-31 |
Dharmacon, Inc. |
siRNA targeting v-myc myelocytomatosis viral oncogene homolog (MYC)
|
|
US7906326B2
(en)
|
2003-05-07 |
2011-03-15 |
Rosetta Genomics Ltd. |
Bioinformatically detectable group of novel regulatory oligonucleotides associated with alzheimer's disease and uses thereof
|
|
US9228186B2
(en)
|
2002-11-14 |
2016-01-05 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
|
US7691998B2
(en)
*
|
2002-11-14 |
2010-04-06 |
Dharmacon, Inc. |
siRNA targeting nucleoporin 62kDa (Nup62)
|
|
US7655785B1
(en)
|
2002-11-14 |
2010-02-02 |
Rosetta Genomics Ltd. |
Bioinformatically detectable group of novel regulatory oligonucleotides and uses thereof
|
|
US7612196B2
(en)
*
|
2002-11-14 |
2009-11-03 |
Dharmacon, Inc. |
siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
|
|
US9839649B2
(en)
|
2002-11-14 |
2017-12-12 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
|
US9771586B2
(en)
|
2002-11-14 |
2017-09-26 |
Thermo Fisher Scientific Inc. |
RNAi targeting ZNF205
|
|
US20080268457A1
(en)
*
|
2002-11-14 |
2008-10-30 |
Dharmacon, Inc. |
siRNA targeting forkhead box P3 (FOXP3)
|
|
US7635770B2
(en)
*
|
2002-11-14 |
2009-12-22 |
Dharmacon, Inc. |
siRNA targeting protein kinase N-3 (PKN-3)
|
|
US9879266B2
(en)
|
2002-11-14 |
2018-01-30 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
|
US9719094B2
(en)
|
2002-11-14 |
2017-08-01 |
Thermo Fisher Scientific Inc. |
RNAi targeting SEC61G
|
|
US8198427B1
(en)
*
|
2002-11-14 |
2012-06-12 |
Dharmacon, Inc. |
SiRNA targeting catenin, beta-1 (CTNNB1)
|
|
US20100113307A1
(en)
*
|
2002-11-14 |
2010-05-06 |
Dharmacon, Inc. |
siRNA targeting vascular endothelial growth factor (VEGF)
|
|
WO2006006948A2
(en)
*
|
2002-11-14 |
2006-01-19 |
Dharmacon, Inc. |
METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY
|
|
US7781575B2
(en)
|
2002-11-14 |
2010-08-24 |
Dharmacon, Inc. |
siRNA targeting tumor protein 53 (p53)
|
|
US9719092B2
(en)
|
2002-11-14 |
2017-08-01 |
Thermo Fisher Scientific Inc. |
RNAi targeting CNTD2
|
|
US7592442B2
(en)
*
|
2002-11-14 |
2009-09-22 |
Dharmacon, Inc. |
siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2)
|
|
US7250496B2
(en)
|
2002-11-14 |
2007-07-31 |
Rosetta Genomics Ltd. |
Bioinformatically detectable group of novel regulatory genes and uses thereof
|
|
US20090227780A1
(en)
*
|
2002-11-14 |
2009-09-10 |
Dharmacon, Inc. |
siRNA targeting connexin 43
|
|
US8090542B2
(en)
*
|
2002-11-14 |
2012-01-03 |
Dharmacon Inc. |
Functional and hyperfunctional siRNA
|
|
US7064337B2
(en)
|
2002-11-19 |
2006-06-20 |
The Regents Of The University Of California |
Radiation detection system for portable gamma-ray spectroscopy
|
|
CA2505416A1
(en)
|
2002-11-21 |
2004-06-10 |
Wyeth |
Methods for diagnosing rcc and other solid tumors
|
|
JP4526228B2
(ja)
*
|
2002-11-22 |
2010-08-18 |
隆 森田 |
RNAiによる新規治療法および治療剤
|
|
AU2003298718A1
(en)
*
|
2002-11-22 |
2004-06-18 |
University Of Massachusetts |
Modulation of hiv replication by rna interference
|
|
EP2112229A3
(en)
|
2002-11-25 |
2009-12-02 |
Sequenom, Inc. |
Methods for identifying risk of breast cancer and treatments thereof
|
|
US20130130231A1
(en)
|
2002-11-26 |
2013-05-23 |
Isaac Bentwich |
Bioinformatically detectable group of novel viral regulatory genes and uses thereof
|
|
US7696334B1
(en)
|
2002-12-05 |
2010-04-13 |
Rosetta Genomics, Ltd. |
Bioinformatically detectable human herpesvirus 5 regulatory gene
|
|
US7217807B2
(en)
|
2002-11-26 |
2007-05-15 |
Rosetta Genomics Ltd |
Bioinformatically detectable group of novel HIV regulatory genes and uses thereof
|
|
AU2003290664A1
(en)
|
2002-11-27 |
2004-06-23 |
Wei Liu |
Compositions, organisms and methodologies employing a novel human kinase
|
|
US20040110698A1
(en)
*
|
2002-12-10 |
2004-06-10 |
Kimron Veterinary Institute |
Oligonucleotides and methods using same for treating cox-ll associated diseases
|
|
AU2004204456A1
(en)
*
|
2003-01-09 |
2004-07-29 |
Invitrogen Corporation |
Cellular delivery and activation polypeptide-nucleic acid complexes
|
|
ATE477337T1
(de)
*
|
2003-01-16 |
2010-08-15 |
Univ Pennsylvania |
Zusammensetzungen und verfahren zur sirna-hemmung von icam-1
|
|
US20040171118A1
(en)
*
|
2003-02-13 |
2004-09-02 |
City Of Hope |
Methods for directing DNA methylation in mammalian cells using homologous short double stranded RNAs
|
|
US20070104688A1
(en)
|
2003-02-13 |
2007-05-10 |
City Of Hope |
Small interfering RNA mediated transcriptional gene silencing in mammalian cells
|
|
US20060294604A1
(en)
*
|
2003-02-17 |
2006-12-28 |
Fridman Jordan S |
Model for studying the role of genes in tumor resistance to chemotherapy
|
|
US20090186839A1
(en)
*
|
2003-02-17 |
2009-07-23 |
Cold Spring Harbor Laboratory |
Model for studying the role of genes in chemoresistance
|
|
US7521534B1
(en)
|
2003-03-03 |
2009-04-21 |
The University Board Of Regents Of Texas System |
IKK gamma gene products and methods for making and using same
|
|
KR20050098954A
(ko)
*
|
2003-03-05 |
2005-10-12 |
세네스코 테크놀로지스 인코포레이티드 |
이아이에프-5에이1의 발현을 억제하기 위한 안티센스올리고뉴클레오타이드 또는 에스아이알엔에이의 이용
|
|
AU2004220556B2
(en)
|
2003-03-07 |
2009-05-07 |
Alnylam Pharmaceuticals, Inc. |
Therapeutic compositions
|
|
GB0306715D0
(en)
*
|
2003-03-24 |
2003-04-30 |
Novartis Ag |
Organic compounds
|
|
US20070197457A1
(en)
|
2003-04-01 |
2007-08-23 |
Dan Gazit |
Tak1-mediated inhibition of osteogenesis
|
|
CA2521464C
(en)
|
2003-04-09 |
2013-02-05 |
Alnylam Pharmaceuticals, Inc. |
Irna conjugates
|
|
JP4912873B2
(ja)
*
|
2003-04-09 |
2012-04-11 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
iRNA複合体
|
|
US20070270360A1
(en)
*
|
2003-04-15 |
2007-11-22 |
Sirna Therapeutics, Inc. |
Rna Interference Mediated Inhibition of Severe Acute Respiratory Syndrome (Sars) Gene Expression Using Short Interfering Nucleic Acid
|
|
US7851615B2
(en)
*
|
2003-04-17 |
2010-12-14 |
Alnylam Pharmaceuticals, Inc. |
Lipophilic conjugated iRNA agents
|
|
AU2013205519B2
(en)
*
|
2003-04-17 |
2015-07-16 |
Alnylam Pharmaceuticals, Inc. |
Modified irna agents
|
|
US8017762B2
(en)
*
|
2003-04-17 |
2011-09-13 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
|
US7723509B2
(en)
|
2003-04-17 |
2010-05-25 |
Alnylam Pharmaceuticals |
IRNA agents with biocleavable tethers
|
|
EP2669377A3
(en)
*
|
2003-04-17 |
2015-10-14 |
Alnylam Pharmaceuticals Inc. |
Modified iRNA agents
|
|
CA2522349A1
(en)
|
2003-04-17 |
2004-11-04 |
Alnylam Pharmaceuticals, Inc. |
Protected monomers
|
|
US8796436B2
(en)
|
2003-04-17 |
2014-08-05 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
|
US7994305B2
(en)
*
|
2003-04-18 |
2011-08-09 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for siRNA inhibition of angiopoietin 1 and 2 and their receptor Tie2
|
|
EP1633784B1
(en)
|
2003-05-09 |
2011-07-13 |
Diadexus, Inc. |
Ovr110 antibody compositions and methods of use
|
|
AU2003902253A0
(en)
|
2003-05-12 |
2003-05-29 |
The University Of Queensland |
Method for increasing product yield
|
|
CA2525619A1
(en)
*
|
2003-05-16 |
2005-03-03 |
Rosetta Inpharmatics, Llc |
Methods and compositions for rna interference
|
|
WO2004106515A1
(ja)
|
2003-05-28 |
2004-12-09 |
Scimedia Ltd. |
抗bambi抗体、及びそれを含有する大腸癌及び肝臓癌の診断剤又は治療剤
|
|
KR20060013426A
(ko)
|
2003-05-30 |
2006-02-09 |
니뽄 신야쿠 가부시키가이샤 |
Bcl-2의 발현을 억제하는 올리고 이중쇄 RNA와그것을 함유하는 의약 조성물
|
|
US7750144B2
(en)
|
2003-06-02 |
2010-07-06 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of RNA silencing
|
|
US7459547B2
(en)
|
2003-06-02 |
2008-12-02 |
University Of Massachusetts |
Methods and compositions for controlling efficacy of RNA silencing
|
|
ATE485394T1
(de)
*
|
2003-06-02 |
2010-11-15 |
Univ Massachusetts |
Verfahren und zusammensetzungen zur verbesserung der wirksamkeit und spezifität von fnai
|
|
NZ543815A
(en)
*
|
2003-06-03 |
2008-08-29 |
Benitec Australia Ltd |
Double-stranded nucleic acid
|
|
BRPI0410886A
(pt)
|
2003-06-03 |
2006-07-04 |
Isis Pharmaceuticals Inc |
composto de filamento duplo, composição farmacêutica, sal farmaceuticamente aceitável, métodos de modificação do ácido nucleico que codifica a survivina humana, de inibição da expressão da suvivina em células ou tecidos, e de tratamento de uma condição associada com a expressão ou superexpressão da suvivina, e, oligonucleotìdeo de rnai de filamento único
|
|
WO2005001051A2
(en)
|
2003-06-06 |
2005-01-06 |
Arborgen Llc. |
Compositions and methods for regulating polysaccharides of a plant cell
|
|
DK2270162T3
(en)
*
|
2003-06-12 |
2019-01-21 |
Alnylam Pharmaceuticals Inc |
PRESERVED HBV AND HCV SEQUENCES USED FOR GEN-SILENCING
|
|
US8575327B2
(en)
*
|
2003-06-12 |
2013-11-05 |
Alnylam Pharmaceuticals, Inc. |
Conserved HBV and HCV sequences useful for gene silencing
|
|
CA2530248A1
(en)
*
|
2003-06-25 |
2005-01-06 |
Gencia Corporation |
Modified vectors for organelle transfection
|
|
FR2857013B1
(fr)
*
|
2003-07-02 |
2005-09-30 |
Commissariat Energie Atomique |
Petits arn interferents specifiques des sous-unites alpha, alpha prime et beta de la proteine kinase ck2 et leurs applications
|
|
JP2007524397A
(ja)
*
|
2003-07-03 |
2007-08-30 |
ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア |
Sykキナーゼ発現の阻害
|
|
CN101291653B
(zh)
*
|
2003-07-16 |
2012-06-27 |
普洛体维生物治疗公司 |
脂质包封的干扰rna
|
|
US20050026290A1
(en)
*
|
2003-08-01 |
2005-02-03 |
Ciardi Joseph Anthony |
Inhibiting gene expression with dsRNA
|
|
US8106180B2
(en)
|
2003-08-07 |
2012-01-31 |
Whitehead Institute For Biomedical Research |
Methods and products for expression of micro RNAs
|
|
US7888497B2
(en)
|
2003-08-13 |
2011-02-15 |
Rosetta Genomics Ltd. |
Bioinformatically detectable group of novel regulatory oligonucleotides and uses thereof
|
|
US7825235B2
(en)
*
|
2003-08-18 |
2010-11-02 |
Isis Pharmaceuticals, Inc. |
Modulation of diacylglycerol acyltransferase 2 expression
|
|
NZ545360A
(en)
|
2003-08-28 |
2009-06-26 |
Novartis Ag |
Interfering RNA duplex having blunt-ends and 3'-modifications
|
|
WO2005021767A1
(en)
*
|
2003-08-28 |
2005-03-10 |
Genpath Pharmaceuticals, Inc. |
Tumor-specific expression of reporter genes
|
|
ES2485848T3
(es)
*
|
2003-09-12 |
2014-08-14 |
University Of Massachusetts |
ARN de interferencia para el tratamiento de trastornos relacionados con la ganancia de función
|
|
US8680063B2
(en)
|
2003-09-12 |
2014-03-25 |
University Of Massachusetts |
RNA interference for the treatment of gain-of-function disorders
|
|
CA2539651A1
(en)
*
|
2003-09-22 |
2005-04-07 |
Rosetta Inpharmatics Llc |
Synthetic lethal screen using rna interference
|
|
US20050282168A1
(en)
*
|
2003-09-29 |
2005-12-22 |
Wyeth |
Cell surface molecules as markers and therapeutic agents against kidney cancers
|
|
EP1711613B1
(en)
|
2003-10-09 |
2013-04-10 |
E.I. Du Pont De Nemours And Company |
Gene silencing by using micro-rna molecules
|
|
CA2543257C
(en)
|
2003-10-24 |
2013-12-31 |
Gencia Corporation |
Methods and compositions for delivering polynucleotides
|
|
US8133733B2
(en)
|
2003-10-24 |
2012-03-13 |
Gencia Corporation |
Nonviral vectors for delivering polynucleotides to target tissues
|
|
US20090123468A1
(en)
|
2003-10-24 |
2009-05-14 |
Gencia Corporation |
Transducible polypeptides for modifying metabolism
|
|
US8507277B2
(en)
*
|
2003-10-24 |
2013-08-13 |
Gencia Corporation |
Nonviral vectors for delivering polynucleotides
|
|
US8062891B2
(en)
|
2003-10-24 |
2011-11-22 |
Gencia Corporation |
Nonviral vectors for delivering polynucleotides to plants
|
|
ES2687645T3
(es)
|
2003-10-27 |
2018-10-26 |
Merck Sharp & Dohme Corp. |
Método de diseño de ARNip para el silenciamiento de genes
|
|
WO2005042722A2
(en)
*
|
2003-10-31 |
2005-05-12 |
University Of Florida Research Foundation, Inc. |
Materials and methods for improved sweet corn
|
|
DE10351149A1
(de)
*
|
2003-11-03 |
2005-06-30 |
Beiersdorf Ag |
Oligoribonukleotide zur Behandlung von unerwünschter Pigmentierung der Haut und der Haare durch RNA-Interferenz
|
|
US9133233B2
(en)
|
2003-11-04 |
2015-09-15 |
Geron Corporation |
RNA amidates and thioamidates for RNAi
|
|
US8227434B1
(en)
|
2003-11-04 |
2012-07-24 |
H. Lee Moffitt Cancer Center & Research Institute, Inc. |
Materials and methods for treating oncological disorders
|
|
WO2005081714A2
(en)
|
2003-11-21 |
2005-09-09 |
Revivicor, Inc. |
Use of interfering rna in the production of transgenic animals
|
|
US20080021205A1
(en)
*
|
2003-12-11 |
2008-01-24 |
Helen Blau |
Methods and Compositions for Use in Preparing Hairpin Rnas
|
|
WO2005068630A1
(ja)
*
|
2003-12-16 |
2005-07-28 |
National Institute Of Advanced Industrial Science And Technology |
干渉用二重鎖rna
|
|
WO2005062937A2
(en)
*
|
2003-12-22 |
2005-07-14 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of single and double blunt-ended sirna
|
|
US20060134787A1
(en)
|
2004-12-22 |
2006-06-22 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of single and double blunt-ended siRNA
|
|
AR047574A1
(es)
|
2003-12-30 |
2006-01-25 |
Arborgen Llc 2 Genesis Res 1 |
Genes del ciclo celular y metodos de uso relacionados
|
|
EP1742661A2
(en)
*
|
2004-01-07 |
2007-01-17 |
Neopharm, Inc. |
Lipid compositions and use thereof
|
|
EP1706511A4
(en)
|
2004-01-23 |
2010-04-07 |
New England Biolabs Inc |
COMPOSITIONS AND METHOD FOR GENERATING SHORT DOUBLE-STRENGTH RNA USING MUTED RNASE III
|
|
US20080249039A1
(en)
*
|
2004-01-30 |
2008-10-09 |
Santaris Pharma A/S |
Modified Short Interfering Rna (Modified Sirna)
|
|
ATE491715T1
(de)
*
|
2004-01-30 |
2011-01-15 |
Quark Pharmaceuticals Inc |
Oligoribonukleotide und verfahren zu deren anwendung bei der behandlung von fibrotischen leiden und anderen krankheiten
|
|
US7655402B2
(en)
|
2004-02-06 |
2010-02-02 |
Wyeth Llc |
Diagnoses and therapeutics for cancer
|
|
WO2005078139A2
(en)
|
2004-02-09 |
2005-08-25 |
Thomas Jefferson University |
DIAGNOSIS AND TREATMENT OF CANCERS WITH MicroRNA LOCATED IN OR NEAR CANCER-ASSOCIATED CHROMOSOMAL FEATURES
|
|
US20060019914A1
(en)
|
2004-02-11 |
2006-01-26 |
University Of Tennessee Research Foundation |
Inhibition of tumor growth and invasion by anti-matrix metalloproteinase DNAzymes
|
|
WO2005079299A2
(en)
*
|
2004-02-12 |
2005-09-01 |
New England Biolabs, Inc. |
HIGHLY POTENT hsiRNA MIXTURES AND METHODS FOR GENE SILENCING
|
|
WO2005079397A2
(en)
*
|
2004-02-13 |
2005-09-01 |
Rockefeller University |
Anti-microrna oligonucleotide molecules
|
|
US20050182005A1
(en)
*
|
2004-02-13 |
2005-08-18 |
Tuschl Thomas H. |
Anti-microRNA oligonucleotide molecules
|
|
US20050273868A1
(en)
*
|
2004-02-17 |
2005-12-08 |
University Of Massachusetts |
Methods and compositions for enhancing RISC activity in vitro and in vivo
|
|
WO2005079533A2
(en)
*
|
2004-02-17 |
2005-09-01 |
University Of Massachusetts |
Methods and compositions for mediating gene silencing
|
|
US7622301B2
(en)
*
|
2004-02-24 |
2009-11-24 |
Basf Plant Science Gmbh |
Compositions and methods using RNA interference for control of nematodes
|
|
EP1737493B1
(en)
|
2004-02-25 |
2011-06-29 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of insulin-like growth factor receptor -1 for inhibiting tumor cell growth
|
|
US20070265220A1
(en)
*
|
2004-03-15 |
2007-11-15 |
City Of Hope |
Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
|
|
US8084599B2
(en)
|
2004-03-15 |
2011-12-27 |
City Of Hope |
Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
|
|
ES2707393T3
(es)
|
2004-03-26 |
2019-04-03 |
Curis Inc |
Moduladores de interferencia de ARN de señalización de hedgehog y usos de los mismos
|
|
KR101147147B1
(ko)
|
2004-04-01 |
2012-05-25 |
머크 샤프 앤드 돔 코포레이션 |
Rna 간섭의 오프 타겟 효과 감소를 위한 변형된폴리뉴클레오타이드
|
|
US8088902B2
(en)
*
|
2004-04-05 |
2012-01-03 |
The Rockefeller University |
DNA virus microRNA and methods for inhibiting same
|
|
JP2007531794A
(ja)
*
|
2004-04-05 |
2007-11-08 |
アルニラム ファーマスーティカルズ インコーポレイテッド |
オリゴヌクレオチドの合成および精製に使用する方法および反応試薬
|
|
US7416842B2
(en)
*
|
2004-04-05 |
2008-08-26 |
The Rockefeller University |
DNA virus microRNA
|
|
US7365058B2
(en)
*
|
2004-04-13 |
2008-04-29 |
The Rockefeller University |
MicroRNA and methods for inhibiting same
|
|
EP1747022A4
(en)
|
2004-04-23 |
2010-03-31 |
Univ Columbia |
INHIBITION OF HAIRLESS PROTEIN MRNA
|
|
MXPA06012258A
(es)
|
2004-04-23 |
2007-03-15 |
Ceres Inc |
Metodos para modificar las caracteristicas de plantas.
|
|
EP1768998A2
(en)
*
|
2004-04-27 |
2007-04-04 |
Alnylam Pharmaceuticals Inc. |
Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety
|
|
EP3034510A1
(en)
*
|
2004-04-30 |
2016-06-22 |
Alnylam Pharmaceuticals Inc. |
Oligonucleotides comprising a c5-modified pyrimidine
|
|
US7605250B2
(en)
*
|
2004-05-12 |
2009-10-20 |
Dharmacon, Inc. |
siRNA targeting cAMP-specific phosphodiesterase 4D
|
|
US7687616B1
(en)
|
2004-05-14 |
2010-03-30 |
Rosetta Genomics Ltd |
Small molecules modulating activity of micro RNA oligonucleotides and micro RNA targets and uses thereof
|
|
EP2322650A1
(en)
|
2004-05-14 |
2011-05-18 |
Rosetta Genomics Ltd |
MicroRNAs and uses thereof
|
|
DE102004025881A1
(de)
|
2004-05-19 |
2006-01-05 |
Beiersdorf Ag |
Oligoribonukleotide zur Beeinflussung des Haarwachstums
|
|
US10508277B2
(en)
|
2004-05-24 |
2019-12-17 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
|
US7795419B2
(en)
|
2004-05-26 |
2010-09-14 |
Rosetta Genomics Ltd. |
Viral and viral associated miRNAs and uses thereof
|
|
EP2290072B1
(en)
|
2004-05-28 |
2014-12-17 |
Asuragen, Inc. |
Methods and compositions involving microRNA
|
|
US8394947B2
(en)
|
2004-06-03 |
2013-03-12 |
Isis Pharmaceuticals, Inc. |
Positionally modified siRNA constructs
|
|
US20140371299A1
(en)
*
|
2004-06-07 |
2014-12-18 |
Senesco Technologies, Inc. |
Use of Apoptosis-Specific elF-5A siRNA to Down Regulate Expression of Proinflammatory Cytokines to Treat Sepsis
|
|
EP1789553B1
(en)
*
|
2004-06-30 |
2014-03-26 |
Alnylam Pharmaceuticals Inc. |
Oligonucleotides comprising a non-phosphate backbone linkage
|
|
WO2006085987A2
(en)
|
2004-07-09 |
2006-08-17 |
University Of Iowa Research Foundation |
Rna interference in respiratory epitheial cells
|
|
US8361976B2
(en)
|
2004-07-09 |
2013-01-29 |
University Of Massachusetts |
Therapeutic alteration of transplantable tissues through in situ or ex vivo exposure to RNA interference molecules
|
|
US7968762B2
(en)
|
2004-07-13 |
2011-06-28 |
Van Andel Research Institute |
Immune-compromised transgenic mice expressing human hepatocyte growth factor (hHGF)
|
|
WO2006019904A1
(en)
|
2004-07-14 |
2006-02-23 |
University Of Utha Research Foundation |
Netrin-related compositions and uses
|
|
EP1781338A4
(en)
|
2004-07-19 |
2010-02-10 |
Baylor College Medicine |
MODULATION OF CYTOKIN SIGNALING REGULATORS AND APPLICATIONS FOR IMMUNOTHERAPY
|
|
WO2006093526A2
(en)
|
2004-07-21 |
2006-09-08 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising a modified or non-natural nucleobase
|
|
WO2006091233A2
(en)
*
|
2004-07-23 |
2006-08-31 |
Boston Medical Center Corporation |
Cellular delivery of reagents that inhibit gene expression utilizing the anthrax toxin protective antigen (pa)
|
|
EP2484780A1
(en)
|
2004-07-23 |
2012-08-08 |
The University of North Carolina At Chapel Hill |
Methods and materials for determining pain sensibility and predicting and treating related disorders
|
|
EP2412816B1
(en)
|
2004-07-26 |
2014-12-03 |
Pfenex Inc. |
Process for improved protein expression by strain engineering
|
|
EP1789070B1
(en)
|
2004-08-03 |
2012-10-24 |
Biogen Idec MA Inc. |
Taj in neuronal function
|
|
AU2005330637B2
(en)
|
2004-08-04 |
2012-09-20 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising a ligand tethered to a modified or non-natural nucleobase
|
|
EP1791567B1
(en)
|
2004-08-10 |
2015-07-29 |
Alnylam Pharmaceuticals Inc. |
Chemically modified oligonucleotides
|
|
EP1789592A4
(en)
*
|
2004-08-13 |
2009-12-23 |
Univ Delaware |
METHOD FOR IDENTIFYING AND QUANTIFYING SHORT OR SMALL ARN
|
|
AR050211A1
(es)
*
|
2004-08-13 |
2006-10-04 |
Basf Plant Science Gmbh |
Composiciones y metodos que usan interferencia de arn para el control de nematodos
|
|
JP4468989B2
(ja)
|
2004-08-16 |
2010-05-26 |
クアーク・ファーマスーティカルス、インコーポレイテッド |
Rtp801阻害剤の治療への使用
|
|
US7893197B2
(en)
|
2004-08-25 |
2011-02-22 |
Janssen Pharmaceutica N.V. |
Relaxin-3 chimeric polypeptides and their preparation and use
|
|
US7323310B2
(en)
*
|
2004-08-31 |
2008-01-29 |
Qiagen North American Holdings, Inc. |
Methods and compositions for RNA amplification and detection using an RNA-dependent RNA-polymerase
|
|
US7884086B2
(en)
|
2004-09-08 |
2011-02-08 |
Isis Pharmaceuticals, Inc. |
Conjugates for use in hepatocyte free uptake assays
|
|
WO2006031859A2
(en)
|
2004-09-14 |
2006-03-23 |
Ceres Inc. |
Modulation of amino acid and sugar content in plants
|
|
US20060059585A1
(en)
|
2004-09-14 |
2006-03-16 |
Boris Jankowski |
Modulating plant sugar levels
|
|
US20060057590A1
(en)
*
|
2004-09-14 |
2006-03-16 |
Azeddine Si-Ammour |
RNA probes
|
|
FI20041204A0
(fi)
|
2004-09-16 |
2004-09-16 |
Riikka Lund |
Menetelmät immuunivälitteisiin sairauksiin liittyvien uusien kohdegeenien hyödyntämiseksi
|
|
US7799906B1
(en)
|
2004-09-22 |
2010-09-21 |
Arborgen, Llc |
Compositions and methods for modulating lignin of a plant
|
|
DK1804836T3
(da)
|
2004-09-24 |
2011-01-24 |
Beth Israel Hospital |
Fremgangsmåder til diagnosticering og behandling af graviditetskomplikationer
|
|
EP1799269B1
(en)
|
2004-09-28 |
2016-09-07 |
Quark Pharmaceuticals, Inc. |
Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases
|
|
BRPI0516874A
(pt)
*
|
2004-10-12 |
2008-09-23 |
Univ Rockefeller |
micrornas
|
|
CA2584785A1
(en)
*
|
2004-10-27 |
2006-05-04 |
Schering Corporation |
Compositions and methods for short interfering nucleic acid inhibition of nav1.8
|
|
US9492400B2
(en)
|
2004-11-04 |
2016-11-15 |
Massachusetts Institute Of Technology |
Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
|
|
ES2534304T3
(es)
|
2004-11-12 |
2015-04-21 |
Asuragen, Inc. |
Procedimientos y composiciones que implican miARN y moléculas inhibidoras de miARN
|
|
JP2008521909A
(ja)
*
|
2004-12-02 |
2008-06-26 |
ビー−ブリッジ インターナショナル,インコーポレーテッド |
短鎖干渉rna、アンチセンスポリヌクレオチド、および他のハイブリッド形成化ポリヌクレオチドの設計方法
|
|
US7517870B2
(en)
|
2004-12-03 |
2009-04-14 |
Fondazione Telethon |
Use of compounds that interfere with the hedgehog signaling pathway for the manufacture of a medicament for preventing, inhibiting, and/or reversing ocular diseases related with ocular neovascularization
|
|
WO2007089610A1
(en)
|
2006-01-26 |
2007-08-09 |
Ceres, Inc. |
Modulating plant oil levels
|
|
WO2006062971A2
(en)
|
2004-12-08 |
2006-06-15 |
Ceres Inc. |
Modulating plant carbon levels
|
|
US20060159738A1
(en)
*
|
2004-12-14 |
2006-07-20 |
Applera Corporation |
Cationic liposomes and methods of use
|
|
BRPI0519657A2
(pt)
|
2004-12-16 |
2009-03-03 |
Ceres Inc |
modulaÇço dos nÍveis de nitrogÊnio em plantas
|
|
US7335760B2
(en)
|
2004-12-22 |
2008-02-26 |
Ceres, Inc. |
Nucleic acid sequences encoding zinc finger proteins
|
|
US20060142228A1
(en)
*
|
2004-12-23 |
2006-06-29 |
Ambion, Inc. |
Methods and compositions concerning siRNA's as mediators of RNA interference
|
|
TWI401316B
(zh)
*
|
2004-12-23 |
2013-07-11 |
Alcon Inc |
用於治療青光眼之血清澱粉樣蛋白A的RNAi抑制作用
|
|
TWI386225B
(zh)
*
|
2004-12-23 |
2013-02-21 |
Alcon Inc |
用於治療眼睛病症的結締組織生長因子(CTGF)RNA干擾(RNAi)抑制技術
|
|
EP2992902A1
(en)
|
2004-12-27 |
2016-03-09 |
Silence Therapeutics GmbH |
Lipid complexes coated with peg and their uses
|
|
US20090005332A1
(en)
*
|
2004-12-30 |
2009-01-01 |
Hauser Todd M |
Compositions and Methods for Modulating Gene Expression Using Self-Protected Oligonucleotides
|
|
WO2006073921A2
(en)
*
|
2004-12-30 |
2006-07-13 |
The Rockefeller University |
Compositions and methods for enhanced dendritic cell maturation and function
|
|
US8137907B2
(en)
*
|
2005-01-03 |
2012-03-20 |
Cold Spring Harbor Laboratory |
Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof
|
|
US7964195B2
(en)
|
2005-01-07 |
2011-06-21 |
Diadexus, Inc. |
Ovr110 antibody compositions and methods of use
|
|
US7718625B2
(en)
|
2005-01-27 |
2010-05-18 |
University Of South Florida |
Polynucleotides targeted against the extended 5′-UTR region of argininosuccinate synthase and uses thereof
|
|
TW200639253A
(en)
*
|
2005-02-01 |
2006-11-16 |
Alcon Inc |
RNAi-mediated inhibition of ocular targets
|
|
WO2006084053A1
(en)
*
|
2005-02-02 |
2006-08-10 |
Achillion Pharmaceuticals, Inc. |
8-n-substituted-2h-isothiazolo[5,4-b]quinolizine-3,4-diones and related compounds as antiinfective agents
|
|
CA2597411C
(en)
|
2005-02-14 |
2014-08-12 |
University Of Iowa Research Foundation |
Use of complement factor h polymorphisms in treatment and diagnosis of age-related macular degeneration
|
|
US20060281680A1
(en)
|
2005-03-10 |
2006-12-14 |
Genentech, Inc. |
Methods and compositions for modulating vascular integrity
|
|
KR20080018858A
(ko)
|
2005-03-11 |
2008-02-28 |
알콘, 인코퍼레이티드 |
녹내장 치료용 플리즐 관련 단백질―1의 RNAⅰ-중재저해
|
|
DE202005004135U1
(de)
*
|
2005-03-11 |
2005-05-19 |
Klocke Verpackungs-Service Gmbh |
Mehrkomponentenverpackung mit Applikator
|
|
GB0505081D0
(en)
*
|
2005-03-14 |
2005-04-20 |
Genomica Sau |
Downregulation of interleukin-12 expression by means of rnai technology
|
|
US8999943B2
(en)
|
2005-03-14 |
2015-04-07 |
Board Of Regents, The University Of Texas System |
Antigene oligomers inhibit transcription
|
|
EP3312196B1
(en)
|
2005-03-23 |
2019-07-17 |
Genmab A/S |
Antibodies against cd38 for treatment of multiple myeloma
|
|
EP2098593B1
(en)
|
2005-04-15 |
2011-12-28 |
National University Corporation Tottori University |
hTERT expression regulatory gene
|
|
WO2006113743A2
(en)
*
|
2005-04-18 |
2006-10-26 |
Massachusetts Institute Of Technology |
Compositions and methods for rna interference with sialidase expression and uses thereof
|
|
CA2605701C
(en)
|
2005-04-29 |
2015-12-08 |
Rockefeller University |
Human micrornas and methods for inhibiting same
|
|
US20090042186A1
(en)
*
|
2005-05-06 |
2009-02-12 |
Alexander Mankin |
Mapping new sites for antibiotic action in the ribosome
|
|
KR100694804B1
(ko)
|
2005-05-18 |
2007-03-14 |
아주대학교산학협력단 |
작은 헤어핀 rna 분자를 포함하는 자궁 내막암 치료또는 예방용 조성물 및 그를 이용한 자궁 내막암 치료 또는예방 방법
|
|
CA2610265A1
(en)
|
2005-05-31 |
2007-05-10 |
Cold Spring Harbor Laboratory |
Methods for producing micrornas
|
|
EP1888749B1
(en)
|
2005-06-01 |
2014-10-15 |
Polyplus Transfection |
Oligonucleotides for rna interference and biological applications thereof
|
|
US20100266574A1
(en)
*
|
2005-06-10 |
2010-10-21 |
Orna Mor |
Oligoribonucleotides and Methods of Use Thereof for Treatment of Fibrotic Conditions and Other Diseases
|
|
WO2006135862A2
(en)
|
2005-06-10 |
2006-12-21 |
Children's Hospital And Research Center At Oakland |
Immunomodulation by altering sphingosine 1-phosphate lyase (spl) activity
|
|
BRPI0613141A2
(pt)
|
2005-06-17 |
2012-12-11 |
Arborgen Llc |
polinucleotìdios isolados, construção de dna, célula de planta, planta transgênica, madeira e polpa de madeira
|
|
US7868159B2
(en)
|
2005-06-23 |
2011-01-11 |
Baylor College Of Medicine |
Modulation of negative immune regulators and applications for immunotherapy
|
|
ES2435774T3
(es)
|
2005-07-07 |
2013-12-23 |
Yissum Research Development Company, Of The Hebrew University Of Jerusalem |
Agentes de ácido nucleico para la regulación negativa de H19, y métodos de uso del mismo
|
|
US20090270479A1
(en)
*
|
2005-07-12 |
2009-10-29 |
Antonio Giordano |
Genetic and Epigenetic Alterations In the Diagnosis and Treatment of Cancer
|
|
WO2007011702A2
(en)
|
2005-07-15 |
2007-01-25 |
The University Of North Carolina At Chapel Hill |
Use of egfr inhibitors to prevent or treat obesity
|
|
US20070111227A1
(en)
*
|
2005-07-28 |
2007-05-17 |
Green Pamela J |
Small regulatory RNAs and methods of use
|
|
US20090176725A1
(en)
*
|
2005-08-17 |
2009-07-09 |
Sirna Therapeutics Inc. |
Chemically modified short interfering nucleic acid molecules that mediate rna interference
|
|
WO2007022470A2
(en)
*
|
2005-08-18 |
2007-02-22 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for treating neurological disease
|
|
WO2007026958A1
(ja)
|
2005-09-01 |
2007-03-08 |
Suntory Limited |
トリプトファントランスポーター遺伝子及びその用途
|
|
EP1762575A1
(en)
|
2005-09-12 |
2007-03-14 |
Ganymed Pharmaceuticals AG |
Identification of tumor-associated antigens for diagnosis and therapy
|
|
EP1937280B1
(en)
|
2005-09-12 |
2014-08-27 |
The Ohio State University Research Foundation |
Compositions for the therapy of bcl2-associated cancers
|
|
CN101268194A
(zh)
|
2005-09-20 |
2008-09-17 |
巴斯福植物科学有限公司 |
使用ta-siRNA调控基因表达的方法
|
|
US8168584B2
(en)
|
2005-10-08 |
2012-05-01 |
Potentia Pharmaceuticals, Inc. |
Methods of treating age-related macular degeneration by compstatin and analogs thereof
|
|
US7723314B1
(en)
*
|
2005-10-28 |
2010-05-25 |
Transderm, Inc. |
Methods and compositions for treating pachyonychia congenita
|
|
CA2627535A1
(en)
*
|
2005-11-11 |
2007-05-24 |
A. Raymond Frackelton, Jr. |
P66-shc as predictive marker in cancer treatment
|
|
JP5066095B2
(ja)
|
2005-11-17 |
2012-11-07 |
ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム |
染色体dnaに標的化されるオリゴマーによる遺伝子発現の調節
|
|
EP1960778A2
(fr)
*
|
2005-11-25 |
2008-08-27 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Procede pour la mise en evidence de la presence ou de l'absence de marqueurs (eef1a1 ou mark3 ) associes a la presence et/ou a la chimiosensibilite des tumeurs
|
|
DK2463387T3
(en)
|
2005-11-29 |
2017-01-09 |
Cambridge Entpr Ltd |
Markers for breast cancer
|
|
JP4737531B2
(ja)
|
2005-12-05 |
2011-08-03 |
サントリーホールディングス株式会社 |
形質転換酵母を用いるセラミドの製造方法
|
|
EP1795596A1
(en)
|
2005-12-08 |
2007-06-13 |
Ganymed Pharmaceuticals AG |
Composition and methods for therapy and diagnosis of cancer
|
|
WO2007067733A2
(en)
*
|
2005-12-09 |
2007-06-14 |
Massachusetts Institute Of Technology |
Compositions and methods to monitor rna delivery to cells
|
|
US10647960B2
(en)
|
2005-12-13 |
2020-05-12 |
The Trustees Of The University Of Pennsylvania |
Transcriptome transfer produces cellular phenotype conversion
|
|
US9157066B2
(en)
|
2005-12-13 |
2015-10-13 |
The Trustees Of The University Of Pennsylvania |
Transcriptome transfer produces cellular phenotype conversion
|
|
EP1963514B1
(en)
|
2005-12-13 |
2013-08-14 |
The Trustees of The University of Pennsylvania |
Methods for phototransfecting nucleic acid into live cells
|
|
US9267937B2
(en)
|
2005-12-15 |
2016-02-23 |
Massachusetts Institute Of Technology |
System for screening particles
|
|
EP2221378B1
(en)
|
2005-12-22 |
2013-04-17 |
OPKO Pharmaceuticals, LLC |
Compositions and methods for regulating complement system
|
|
BRPI0620806B8
(pt)
|
2005-12-30 |
2022-07-05 |
Evonik Roehm Gmbh |
complexo e composição compreendendo um peptídeo e uma molécula carga, e uso da referida composição
|
|
JP5490413B2
(ja)
|
2006-01-05 |
2014-05-14 |
ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション |
膵内分泌腫瘍及び膵腺房腫瘍におけるマイクロrna発現異常
|
|
EP2487261B1
(en)
|
2006-01-05 |
2015-07-01 |
The Ohio State University Research Foundation |
MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers
|
|
ES2429404T3
(es)
|
2006-01-05 |
2013-11-14 |
The Ohio State University Research Foundation |
Procedimientos basados en los microARN para el diagnóstico y el pronóstico del cáncer de pulmón
|
|
EP1970078A4
(en)
|
2006-01-11 |
2010-11-17 |
Kyowa Hakko Kirin Co Ltd |
COMPOSITION INHIBITING THE EXPRESSION OF A TARGET GENE OF THE OCULAR GLOBE AND REMEDY FOR OCULAR GLOBE DISEASE
|
|
US20090060921A1
(en)
*
|
2006-01-17 |
2009-03-05 |
Biolex Therapeutics, Inc. |
Glycan-optimized anti-cd20 antibodies
|
|
MX2008009220A
(es)
*
|
2006-01-17 |
2008-10-10 |
Biolex Therapeutics Inc |
Composiciones y metodos para la humanizacion y optimizacion de n-glicanos en plantas.
|
|
US7825099B2
(en)
|
2006-01-20 |
2010-11-02 |
Quark Pharmaceuticals, Inc. |
Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
|
|
DOP2007000015A
(es)
|
2006-01-20 |
2007-08-31 |
Quark Biotech Inc |
Usos terapéuticos de inhibidores de rtp801
|
|
US20120208824A1
(en)
|
2006-01-20 |
2012-08-16 |
Cell Signaling Technology, Inc. |
ROS Kinase in Lung Cancer
|
|
EP3360965A1
(en)
|
2006-01-20 |
2018-08-15 |
Cell Signaling Technology, Inc. |
Translocation and mutant ros kinase in human non-small cell lung carcinoma
|
|
EP1984382B1
(en)
*
|
2006-01-27 |
2012-08-15 |
Santaris Pharma A/S |
Lna modified phosphorothiolated oligonucleotides
|
|
JP5829373B2
(ja)
|
2006-01-27 |
2015-12-09 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
Nogoレセプターアンタゴニスト
|
|
WO2007095113A2
(en)
|
2006-02-10 |
2007-08-23 |
Massachusetts Institute Of Technology |
Cpg15 and cpg15-2 compounds and inhibitors as insulin receptor and insulin-like growth factor receptor agonists and antagonists
|
|
WO2007097113A1
(en)
|
2006-02-24 |
2007-08-30 |
Suntory Limited |
Gene encoding protein responsible for flocculation property of yeast and use thereof
|
|
US20090047381A1
(en)
|
2006-02-24 |
2009-02-19 |
Suntory Limited |
Ammonia transporter gene and use thereof
|
|
AU2006339193B2
(en)
|
2006-02-24 |
2009-12-17 |
Suntory Holdings Limited |
Gene encoding protein responsible for flocculation property of yeast and use thereof
|
|
WO2007103808A2
(en)
|
2006-03-02 |
2007-09-13 |
The Ohio State University |
Microrna expression profile associated with pancreatic cancer
|
|
US7910566B2
(en)
|
2006-03-09 |
2011-03-22 |
Quark Pharmaceuticals Inc. |
Prevention and treatment of acute renal failure and other kidney diseases by inhibition of p53 by siRNA
|
|
FI20060246A0
(fi)
|
2006-03-16 |
2006-03-16 |
Jukka Westermarck |
Uusi kasvua stimuloiva proteiini ja sen käyttö
|
|
CA2646051A1
(en)
|
2006-03-20 |
2007-09-27 |
Carlo M. Croce |
Microrna fingerprints during human megakaryocytopoiesis
|
|
JP2009529917A
(ja)
|
2006-03-22 |
2009-08-27 |
ヴァイラル ロジック システムズ テクノロジー コーポレーション |
標的ポリペプチドの同定方法および免疫学的疾患の治療のためのその使用
|
|
EP2002004B1
(en)
*
|
2006-03-23 |
2015-10-14 |
Roche Innovation Center Copenhagen A/S |
Small internally segmented interfering rna
|
|
FR2898908A1
(fr)
|
2006-03-24 |
2007-09-28 |
Agronomique Inst Nat Rech |
Procede de preparation de cellules aviaires differenciees et genes impliques dans le maintien de la pluripotence
|
|
EP2007435B1
(en)
|
2006-03-31 |
2019-12-18 |
Massachusetts Institute Of Technology |
System for targeted delivery of therapeutic agents
|
|
JP5524610B2
(ja)
|
2006-04-07 |
2014-06-18 |
ザ リサーチ ファウンデーション オブ ステイト ユニバーシティー オブ ニューヨーク |
トランスコバラミン受容体ポリペプチド、核酸およびその調節因子、ならびに細胞の増殖の調節ならびにガンおよびコバラミン欠損症の処置に使用する関連方法
|
|
US9044461B2
(en)
|
2006-04-07 |
2015-06-02 |
The Research Foundation Of State University Of New York |
Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency
|
|
EP2018873A4
(en)
|
2006-04-07 |
2009-12-09 |
Japan Found Cancer |
Prophylactic/therapeutic agent for cancer
|
|
EP2012815A4
(en)
*
|
2006-04-14 |
2009-12-09 |
Massachusetts Inst Technology |
IDENTIFICATION AND MODULATION OF MOLECULAR PATHS FOR PROCESSING NEURONAL PLASTICITY
|
|
EP3266867A1
(en)
|
2006-04-14 |
2018-01-10 |
Cell Signaling Technology, Inc. |
Gene defects and mutant alk kinase in human solid tumors
|
|
EP2051585A4
(en)
|
2006-04-28 |
2010-06-02 |
Univ South Florida |
MATERIALS AND METHODS OF SUPPRESSING INFLAMMATION THROUGH INHIBITION OF THE VORHOF RECEPTOR FOR NATRIURETIC PEPTIDES
|
|
GB0608838D0
(en)
|
2006-05-04 |
2006-06-14 |
Novartis Ag |
Organic compounds
|
|
CA2652280C
(en)
|
2006-05-15 |
2014-01-28 |
Massachusetts Institute Of Technology |
Polymers for functional particles
|
|
WO2007132867A1
(ja)
|
2006-05-15 |
2007-11-22 |
Takeda Pharmaceutical Company Limited |
癌の予防及び治療剤
|
|
EP2035439A4
(en)
|
2006-06-05 |
2010-01-13 |
Cancer Care Ontario |
ASSESSMENT OF THE RISK OF COLORECTAL CANCER
|
|
WO2007141796A2
(en)
|
2006-06-09 |
2007-12-13 |
Quark Pharmaceuticals, Inc. |
Therapeutic uses of inhibitors of rtp801l
|
|
US20080152654A1
(en)
*
|
2006-06-12 |
2008-06-26 |
Exegenics, Inc., D/B/A Opko Health, Inc. |
COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF ANGIOGENESIS
|
|
US9381477B2
(en)
|
2006-06-23 |
2016-07-05 |
Massachusetts Institute Of Technology |
Microfluidic synthesis of organic nanoparticles
|
|
WO2008008430A2
(en)
|
2006-07-13 |
2008-01-17 |
The Ohio State University Research Foundation |
Micro-rna-based methods and compositions for the diagnosis and treatment of colon cancer-related diseases
|
|
JP5431151B2
(ja)
|
2006-07-13 |
2014-03-05 |
ユニバーシティー オブ アイオワ リサーチ ファンデーション |
血管障害および加齢黄斑変性症の治療および診断のための方法および試薬
|
|
CN101490253A
(zh)
|
2006-07-21 |
2009-07-22 |
赛伦斯治疗公司 |
用于抑制蛋白激酶3表达的方法
|
|
EP2046954A2
(en)
|
2006-07-31 |
2009-04-15 |
Curevac GmbH |
NUCLEIC ACID OF FORMULA (I): GIXmGn, OR (II): CIXmCn, IN PARTICULAR AS AN IMMUNE-STIMULATING AGENT/ADJUVANT
|
|
WO2008019142A2
(en)
*
|
2006-08-04 |
2008-02-14 |
Massachusetts Institute Of Technology |
Oligonucleotide systems for targeted intracellular delivery
|
|
US7872118B2
(en)
*
|
2006-09-08 |
2011-01-18 |
Opko Ophthalmics, Llc |
siRNA and methods of manufacture
|
|
JPWO2008032876A1
(ja)
|
2006-09-15 |
2010-01-28 |
学校法人東海大学 |
Er陰性およびher2陰性である乳癌の予防または治療剤およびそのスクリーニング方法
|
|
EP2076599A2
(en)
*
|
2006-09-19 |
2009-07-08 |
Asuragen, Inc. |
Mir-200 regulated genes and pathways as targets for therapeutic intervention
|
|
EP2145001A2
(en)
*
|
2006-09-19 |
2010-01-20 |
Asuragen, Inc. |
Mir-15, mir-26, mir -31,mir -145, mir-147, mir-188, mir-215, mir-216 mir-331, mmu-mir-292-3p regulated genes and pathways as targets for therapeutic intervention
|
|
EP1911851A1
(en)
|
2006-10-12 |
2008-04-16 |
Ganymed Pharmaceuticals AG |
Compositions and methods for therapy and diagnosis of cancer and cancer metastasis
|
|
JP2010507387A
(ja)
|
2006-10-25 |
2010-03-11 |
クアーク・ファーマスーティカルス、インコーポレイテッド |
新規のsiRNAおよびその使用方法
|
|
WO2008052774A2
(en)
|
2006-10-31 |
2008-05-08 |
Noxxon Pharma Ag |
Methods for detection of a single- or double-stranded nucleic acid molecule
|
|
DE602007014389D1
(de)
|
2006-11-01 |
2011-06-16 |
Medical Res And Infrastructure Fund Of The Tel Aviv |
Adipozytenspezifische konstrukte und verfahren zur hemmung der expression von blutplättchen-typ-12-lipoxygenase
|
|
WO2008060448A2
(en)
|
2006-11-10 |
2008-05-22 |
Massachusetts Institute Of Technology |
Small molecule pak inhibitors
|
|
CA2683287A1
(en)
|
2006-11-27 |
2008-12-18 |
Patrys Limited |
Novel glycosylated peptide target in neoplastic cells
|
|
US8444971B2
(en)
|
2006-11-27 |
2013-05-21 |
Diadexus, Inc. |
OVR110 antibody compositions and methods of use
|
|
DK2104737T3
(da)
*
|
2006-12-08 |
2013-05-27 |
Asuragen Inc |
Funktioner og formål for let-7 mikro-RNAer
|
|
WO2008073920A2
(en)
*
|
2006-12-08 |
2008-06-19 |
Asuragen, Inc. |
Mir-21 regulated genes and pathways as targets for therapeutic intervention
|
|
AU2007333225B2
(en)
*
|
2006-12-08 |
2014-06-12 |
Massachusetts Institute Of Technology |
Delivery of nanoparticles and/or agents to cells
|
|
US8476243B2
(en)
|
2006-12-29 |
2013-07-02 |
Transderm, Inc. |
Methods and compositions for treating keratin hyperproliferative disorders
|
|
US20090175827A1
(en)
*
|
2006-12-29 |
2009-07-09 |
Byrom Mike W |
miR-16 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION
|
|
US8975068B2
(en)
|
2007-01-25 |
2015-03-10 |
The General Hospital Corporation |
Isolated stem cell comprising a Xic flanking region transgene
|
|
CA2676143A1
(en)
|
2007-01-26 |
2008-07-31 |
University Of Louisville Research Foundation, Inc. |
Modification of exosomal components for use as a vaccine
|
|
US8530436B2
(en)
|
2007-01-29 |
2013-09-10 |
Transderm, Inc. |
Methods and compositions for transdermal delivery of nucleotides
|
|
WO2008098165A2
(en)
|
2007-02-09 |
2008-08-14 |
Massachusetts Institute Of Technology |
Oscillating cell culture bioreactor
|
|
US7872119B2
(en)
|
2007-02-26 |
2011-01-18 |
Quark Pharmaceuticals, Inc. |
Inhibitors of RTP801 and their use in disease treatment
|
|
US20100292301A1
(en)
*
|
2007-02-28 |
2010-11-18 |
Elena Feinstein |
Novel sirna structures
|
|
CA2679954A1
(en)
|
2007-03-05 |
2008-09-12 |
Cancer Care Ontario |
Assessment of risk for colorectal cancer
|
|
EP2139908A4
(en)
|
2007-03-12 |
2011-02-16 |
Antigen Express Inc |
REMOVAL OF PROTEIN Li INVOLVED IN Li-RNAi CONSTRUCTIONS IN ANTICANCER IMMUNOTHERAPY
|
|
WO2008115387A2
(en)
*
|
2007-03-15 |
2008-09-25 |
University Hospitals Of Cleveland |
Screening, diagnosing, treating and prognosis of pathophysiologic states by rna regulation
|
|
WO2008115556A2
(en)
*
|
2007-03-19 |
2008-09-25 |
Cold Spring Harbor Laboratory |
Identification of genetic alterations that modulate drug sensitivity in cancer treatments
|
|
US7812002B2
(en)
|
2007-03-21 |
2010-10-12 |
Quark Pharmaceuticals, Inc. |
Oligoribonucleotide inhibitors of NRF2 and methods of use thereof for treatment of cancer
|
|
WO2008116347A1
(en)
|
2007-03-26 |
2008-10-02 |
General Regeneratives Limited |
Methods for promoting protection and regeneration of bone marrow using cxcl9 and anti-cxcl9 antibodies
|
|
EP2159281B1
(en)
|
2007-03-30 |
2012-09-26 |
National University Corporation Okayama University |
Novel slc17-type transporter protein in mammal and use thereof
|
|
JP5344517B2
(ja)
|
2007-03-30 |
2013-11-20 |
サントリーホールディングス株式会社 |
小胞体局在化シグナル付スフィンゴリピッドδ4−デサチュラーゼを用いた形質転換細胞におけるセラミドの製造方法
|
|
WO2008124634A1
(en)
|
2007-04-04 |
2008-10-16 |
Massachusetts Institute Of Technology |
Polymer-encapsulated reverse micelles
|
|
JP2010523595A
(ja)
|
2007-04-04 |
2010-07-15 |
マサチューセッツ インスティテュート オブ テクノロジー |
ポリ(アミノ酸)ターゲッティング部分
|
|
US20090010941A1
(en)
*
|
2007-04-09 |
2009-01-08 |
University Of Massachusetts |
Methods for treating HIV
|
|
DK2644205T3
(en)
|
2007-04-12 |
2018-09-24 |
Brigham & Womens Hospital Inc |
Targeting ABCB5 for Cancer Therapy
|
|
EP2615172A1
(en)
|
2007-04-27 |
2013-07-17 |
Pfenex Inc. |
Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
|
|
US9580719B2
(en)
|
2007-04-27 |
2017-02-28 |
Pfenex, Inc. |
Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
|
|
US11078262B2
(en)
|
2007-04-30 |
2021-08-03 |
Allergan, Inc. |
High viscosity macromolecular compositions for treating ocular conditions
|
|
WO2008143774A2
(en)
*
|
2007-05-01 |
2008-11-27 |
University Of Massachusetts |
Methods and compositions for locating snp heterozygosity for allele specific diagnosis and therapy
|
|
WO2008143786A1
(en)
*
|
2007-05-14 |
2008-11-27 |
The Rockefeller University |
Production of artificial micrornas using synthetic microrna precursors
|
|
US8314227B2
(en)
|
2007-05-22 |
2012-11-20 |
Marina Biotech, Inc. |
Hydroxymethyl substituted RNA oligonucleotides and RNA complexes
|
|
US20090131354A1
(en)
*
|
2007-05-22 |
2009-05-21 |
Bader Andreas G |
miR-126 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION
|
|
KR20100031528A
(ko)
|
2007-06-01 |
2010-03-22 |
더 트러스티즈 오브 프린스턴 유니버시티 |
숙주세포 대사경로의 조절을 통한 바이러스 감염 치료
|
|
WO2008154470A1
(en)
*
|
2007-06-08 |
2008-12-18 |
University Of Connecticut |
Nhibitor of the receptor activity of the s1p2 receptor for inhibiting pathological angiogenesis in the eye
|
|
HRP20140522T1
(hr)
|
2007-06-27 |
2014-08-15 |
Quark Pharmaceuticals, Inc. |
Pripravci i metode za inhibiranje izražaja proapoptotiäśkih gena
|
|
JP5298014B2
(ja)
|
2007-07-03 |
2013-09-25 |
杏林製薬株式会社 |
インフルエンザ治療
|
|
CA2692861A1
(en)
|
2007-07-10 |
2009-01-15 |
Neurim Pharmaceuticals (1991) Ltd. |
Cd44 splice variants in neurodegenerative diseases
|
|
WO2009012263A2
(en)
*
|
2007-07-18 |
2009-01-22 |
The Trustees Of Columbia University In The City Of New York |
Tissue-specific micrornas and compositions and uses thereof
|
|
CA2695184A1
(en)
|
2007-07-31 |
2009-02-05 |
The Ohio State University Research Foundation |
Methods for reverting methylation by targeting dnmt3a and dnmt3b
|
|
WO2009054873A2
(en)
|
2007-08-02 |
2009-04-30 |
Novimmune S.A. |
Anti-rantes antibodies and methods of use thereof
|
|
ES2570359T3
(es)
|
2007-08-03 |
2016-05-18 |
Univ Ohio State Res Found |
Regiones ultraconservadas que codifican ARNnc
|
|
EP2185702A4
(en)
*
|
2007-08-21 |
2011-05-04 |
Scott And White Memorial Hospital And Scott Sherwood And Brindley Foundation |
METHOD AND COMPOSITIONS POST-TRANSLUCTIVE SWITCH-OFF
|
|
EP3028708A1
(en)
|
2007-08-22 |
2016-06-08 |
The Ohio State University Research Foundation |
Methods and compositions for inducing deregulation of epha7 and erk phosphorylation in human acute leukemias
|
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
|
WO2009033027A2
(en)
|
2007-09-05 |
2009-03-12 |
Medtronic, Inc. |
Suppression of scn9a gene expression and/or function for the treatment of pain
|
|
AU2008296022B2
(en)
|
2007-09-06 |
2014-01-23 |
The Ohio State University Research Foundation |
MicroRNA signatures in human ovarian cancer
|
|
EP2198050A1
(en)
*
|
2007-09-14 |
2010-06-23 |
Asuragen, INC. |
Micrornas differentially expressed in cervical cancer and uses thereof
|
|
EP2548962B1
(en)
|
2007-09-19 |
2016-01-13 |
Applied Biosystems, LLC |
Sirna sequence-independent modification formats for reducing off-target phenotypic effects in rnai, and stabilized forms thereof
|
|
WO2009044392A2
(en)
|
2007-10-03 |
2009-04-09 |
Quark Pharmaceuticals, Inc. |
Novel sirna structures
|
|
CA2702241A1
(en)
|
2007-10-11 |
2009-04-16 |
The Ohio State University Research Foundation |
Methods and compositions for the diagnosis and treatment of esophageal adenocarcinomas
|
|
EP3424525A1
(en)
|
2007-10-12 |
2019-01-09 |
Massachusetts Institute Of Technology |
Vaccine nanotechnology
|
|
EP2203558B1
(en)
|
2007-10-18 |
2016-05-04 |
Cell Signaling Technology, Inc. |
Translocation and mutant ros kinase in human non-small cell lung carcinoma
|
|
EP2060583A1
(en)
|
2007-10-23 |
2009-05-20 |
Ganymed Pharmaceuticals AG |
Identification of tumor-associated markers for diagnosis and therapy
|
|
US8097712B2
(en)
*
|
2007-11-07 |
2012-01-17 |
Beelogics Inc. |
Compositions for conferring tolerance to viral disease in social insects, and the use thereof
|
|
US7828840B2
(en)
*
|
2007-11-15 |
2010-11-09 |
Med Institute, Inc. |
Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists
|
|
EP2222344A4
(en)
|
2007-11-30 |
2012-11-07 |
Baylor College Medicine |
VACCINATE COMPOSITIONS WITH DENDRITIC CELLS AND THEIR USE
|
|
US8071562B2
(en)
|
2007-12-01 |
2011-12-06 |
Mirna Therapeutics, Inc. |
MiR-124 regulated genes and pathways as targets for therapeutic intervention
|
|
CA2910760C
(en)
|
2007-12-04 |
2019-07-09 |
Muthiah Manoharan |
Targeting lipids
|
|
WO2009082606A2
(en)
*
|
2007-12-04 |
2009-07-02 |
Alnylam Pharmaceuticals, Inc. |
Folate conjugates
|
|
WO2009073911A1
(en)
*
|
2007-12-10 |
2009-06-18 |
Mater Medical Research Institute |
Treatment and prophylaxis
|
|
US20110105584A1
(en)
*
|
2007-12-12 |
2011-05-05 |
Elena Feinstein |
Rtp80il sirna compounds and methods of use thereof
|
|
US8614311B2
(en)
|
2007-12-12 |
2013-12-24 |
Quark Pharmaceuticals, Inc. |
RTP801L siRNA compounds and methods of use thereof
|
|
US20090192114A1
(en)
*
|
2007-12-21 |
2009-07-30 |
Dmitriy Ovcharenko |
miR-10 Regulated Genes and Pathways as Targets for Therapeutic Intervention
|
|
EP2242854A4
(en)
*
|
2008-01-15 |
2012-08-15 |
Quark Pharmaceuticals Inc |
COMPOUNDS AND USES THEREOF
|
|
CA2710534C
(en)
|
2008-01-31 |
2018-09-04 |
Curevac Gmbh |
Nucleic acids of formula (i) (nuglxmgnnv)a and derivatives thereof as an immunostimulating agent/adjuvant
|
|
WO2009100430A2
(en)
*
|
2008-02-08 |
2009-08-13 |
Asuragen, Inc |
miRNAs DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS
|
|
US10131904B2
(en)
*
|
2008-02-11 |
2018-11-20 |
Rxi Pharmaceuticals Corporation |
Modified RNAi polynucleotides and uses thereof
|
|
US20090233297A1
(en)
*
|
2008-03-06 |
2009-09-17 |
Elizabeth Mambo |
Microrna markers for recurrence of colorectal cancer
|
|
CN102026670A
(zh)
*
|
2008-03-20 |
2011-04-20 |
夸克医药公司 |
用于抑制RTP801的新型siRNA化合物
|
|
EP2271757A2
(en)
*
|
2008-03-26 |
2011-01-12 |
Asuragen, INC. |
Compositions and methods related to mir-16 and therapy of prostate cancer
|
|
WO2009126726A1
(en)
*
|
2008-04-08 |
2009-10-15 |
Asuragen, Inc |
Methods and compositions for diagnosing and modulating human papillomavirus (hpv)
|
|
EP2108701A1
(en)
|
2008-04-10 |
2009-10-14 |
Ganymed Pharmaceuticals AG |
Methods involving MS4A12 and agents targeting MS4A12 for therapy, diagnosis and testing
|
|
WO2009126933A2
(en)
*
|
2008-04-11 |
2009-10-15 |
Alnylam Pharmaceuticals, Inc. |
Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
|
|
CA2721333C
(en)
|
2008-04-15 |
2020-12-01 |
Protiva Biotherapeutics, Inc. |
Novel lipid formulations for nucleic acid delivery
|
|
WO2009144704A2
(en)
*
|
2008-04-15 |
2009-12-03 |
Quark Pharmaceuticals, Inc. |
siRNA COMPOUNDS FOR INHIBITING NRF2
|
|
EP2116602A1
(en)
|
2008-05-07 |
2009-11-11 |
Institut Gustave Roussy |
Combination products for treating cancer
|
|
US8258111B2
(en)
*
|
2008-05-08 |
2012-09-04 |
The Johns Hopkins University |
Compositions and methods related to miRNA modulation of neovascularization or angiogenesis
|
|
CA2726052A1
(en)
|
2008-06-04 |
2009-12-10 |
The Board Of Regents Of The University Of Texas System |
Modulation of gene expression through endogenous small rna targeting of gene promoters
|
|
US8431692B2
(en)
*
|
2008-06-06 |
2013-04-30 |
Quark Pharmaceuticals, Inc. |
Compositions and methods for treatment of ear disorders
|
|
TWI455944B
(zh)
|
2008-07-01 |
2014-10-11 |
Daiichi Sankyo Co Ltd |
雙股多核苷酸
|
|
US8815818B2
(en)
|
2008-07-18 |
2014-08-26 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell delivery of RNAI
|
|
CN102112136A
(zh)
|
2008-08-01 |
2011-06-29 |
协和发酵麒麟株式会社 |
抑制靶基因表达的组合物
|
|
EP2323695B1
(en)
|
2008-08-19 |
2018-12-05 |
Nektar Therapeutics |
Complexes of small-interfering nucleic acids
|
|
DK2331141T3
(en)
*
|
2008-08-25 |
2016-04-04 |
Excaliard Pharmaceuticals Inc |
Antisense oligonucleotides WHO IS TARGETING connective tissue, AND USES THEREOF
|
|
WO2011028218A1
(en)
|
2009-09-02 |
2011-03-10 |
Alnylam Pharmaceuticals, Inc. |
Process for triphosphate oligonucleotide synthesis
|
|
US20100068200A1
(en)
*
|
2008-09-12 |
2010-03-18 |
The University Of Connecticut |
Methods and Compositions for Inhibiting Atherosclerosis and Vascular Inflammation
|
|
US8796443B2
(en)
|
2008-09-22 |
2014-08-05 |
Rxi Pharmaceuticals Corporation |
Reduced size self-delivering RNAi compounds
|
|
EP3587434A1
(en)
|
2008-09-23 |
2020-01-01 |
Alnylam Pharmaceuticals Inc. |
Chemical modifications of monomers and oligonucleotides with click components for conjugation with ligands
|
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
|
US8343497B2
(en)
|
2008-10-12 |
2013-01-01 |
The Brigham And Women's Hospital, Inc. |
Targeting of antigen presenting cells with immunonanotherapeutics
|
|
US8277812B2
(en)
|
2008-10-12 |
2012-10-02 |
Massachusetts Institute Of Technology |
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
|
|
US8591905B2
(en)
|
2008-10-12 |
2013-11-26 |
The Brigham And Women's Hospital, Inc. |
Nicotine immunonanotherapeutics
|
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
|
JP5232241B2
(ja)
|
2008-10-31 |
2013-07-10 |
独立行政法人科学技術振興機構 |
ヘルパーt細胞の選択的機能制御法
|
|
WO2010054221A2
(en)
|
2008-11-06 |
2010-05-14 |
The Johns Hopkins University |
Treatment of chronic inflammatory respiratory disorders
|
|
DK2355851T3
(en)
|
2008-11-10 |
2018-06-25 |
Arbutus Biopharma Corp |
Newly known lipids and compositions for release of therapeutic agents
|
|
US20100179213A1
(en)
*
|
2008-11-11 |
2010-07-15 |
Mirna Therapeutics, Inc. |
Methods and Compositions Involving miRNAs In Cancer Stem Cells
|
|
WO2010059226A2
(en)
|
2008-11-19 |
2010-05-27 |
Rxi Pharmaceuticals Corporation |
Inhibition of map4k4 through rnai
|
|
BRPI0922355A8
(pt)
|
2008-12-03 |
2017-12-12 |
Marina Biotech Inc |
Ácidos nucléicos, métodos para reduzir a expressão de um gene em uma célula in vitro, uso do ácido nucléico, complexo de rna e uso do complexo de rna
|
|
AU2009322279A1
(en)
|
2008-12-04 |
2011-07-14 |
Opko Pharmaceuticals, Llc |
Compositions and methods for selective inhibition of pro-angiogenic VEGF isoforms
|
|
HUE065752T2
(hu)
|
2008-12-09 |
2024-06-28 |
Hoffmann La Roche |
Anti-PD-L1 antitestek és felhasználásuk T-sejt funkció elõsegítésére
|
|
EP2370175A2
(en)
|
2008-12-16 |
2011-10-05 |
Bristol-Myers Squibb Company |
Methods of inhibiting quiescent tumor proliferation
|
|
US20110288155A1
(en)
|
2008-12-18 |
2011-11-24 |
Elena Feinstein |
Sirna compounds and methods of use thereof
|
|
AU2009330859B2
(en)
|
2008-12-26 |
2013-06-20 |
Samyang Holdings Corporation |
Pharmaceutical composition containing an anionic drug, and a production method therefor
|
|
US9493774B2
(en)
|
2009-01-05 |
2016-11-15 |
Rxi Pharmaceuticals Corporation |
Inhibition of PCSK9 through RNAi
|
|
WO2010090762A1
(en)
|
2009-02-04 |
2010-08-12 |
Rxi Pharmaceuticals Corporation |
Rna duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
|
|
DK2881402T3
(en)
|
2009-02-12 |
2017-08-28 |
Cell Signaling Technology Inc |
Mutant ROS expression in human liver cancer
|
|
EP2395996A1
(en)
|
2009-02-13 |
2011-12-21 |
Indiana University Research and Technology Corporation |
Compounds and methods for inhibiting mmp2 and mmp9
|
|
EP2221063A1
(en)
|
2009-02-20 |
2010-08-25 |
Ganymed Pharmaceuticals AG |
Methods and compositions for diagnosis and treatment of cancer
|
|
EP2221375A1
(en)
|
2009-02-20 |
2010-08-25 |
Ganymed Pharmaceuticals AG |
Methods and compositions for diagnosis and treatment of cancer
|
|
WO2010094499A1
(en)
|
2009-02-20 |
2010-08-26 |
Ganymed Pharmaceuticals Ag |
Methods and compositions for diagnosis and treatment of cancer
|
|
WO2010101951A1
(en)
|
2009-03-02 |
2010-09-10 |
Alnylam Pharmaceuticals, Inc. |
Nucleic acid chemical modifications
|
|
GB2468477A
(en)
|
2009-03-02 |
2010-09-15 |
Mina Therapeutics Ltd |
Double stranded RNA molecule comprising siRNA and miRNA precursors
|
|
US8444983B2
(en)
|
2009-03-23 |
2013-05-21 |
Quark Pharmaceuticals, Inc. |
Composition of anti-ENDO180 antibodies and methods of use for the treatment of cancer and fibrotic diseases
|
|
WO2010124231A2
(en)
|
2009-04-24 |
2010-10-28 |
The Board Of Regents Of The University Of Texas System |
Modulation of gene expression using oligomers that target gene regions downstream of 3' untranslated regions
|
|
EP2249159A1
(en)
|
2009-04-29 |
2010-11-10 |
Ganymed Pharmaceuticals AG |
Identification of tumor-associated markers for diagnosis and therapy
|
|
AU2010244122B2
(en)
|
2009-05-05 |
2015-05-14 |
Beeologics Inc. |
Prevention and treatment of Nosema disease in bees
|
|
CN102414320A
(zh)
*
|
2009-05-15 |
2012-04-11 |
贝林格尔.英格海姆国际有限公司 |
具有降低的nocr表达的改良细胞系及其用途
|
|
EP2432499A2
(en)
|
2009-05-20 |
2012-03-28 |
Schering Corporation |
Modulation of pilr receptors to treat microbial infections
|
|
WO2010141511A2
(en)
|
2009-06-01 |
2010-12-09 |
Halo-Bio Rnai Therapeutics, Inc. |
Polynucleotides for multivalent rna interference, compositions and methods of use thereof
|
|
EP2258858A1
(en)
|
2009-06-05 |
2010-12-08 |
Universitätsklinikum Freiburg |
Transgenic LSD1 animal model for cancer
|
|
CA2764609C
(en)
|
2009-06-10 |
2018-10-02 |
Alnylam Pharmaceuticals, Inc. |
Improved cationic lipid of formula i
|
|
US8435961B2
(en)
|
2009-06-26 |
2013-05-07 |
Massachusetts Institute Of Technology |
Methods and compositions for increasing the activity of inhibitory RNA
|
|
US20110097329A1
(en)
|
2009-06-26 |
2011-04-28 |
Massachusetts Institute Of Technology |
Compositions and methods for treating cancer and modulating stress granule formation
|
|
US8268550B2
(en)
|
2009-06-26 |
2012-09-18 |
Massachusetts Institute Of Technology |
Compositions and methods for identification of PARP function, inhibitors, and activators
|
|
JP5766188B2
(ja)
|
2009-07-01 |
2015-08-19 |
プロチバ バイオセラピューティクス インコーポレイティッド |
固形腫瘍に治療剤を送達するための脂質製剤
|
|
LT2769737T
(lt)
|
2009-07-20 |
2017-06-26 |
Bristol-Myers Squibb Company |
Anti-ctla4 antikūno derinys su etopozidu, skirtas sinerginiam proliferacinių ligų gydymui
|
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
|
US20120263709A1
(en)
|
2009-09-10 |
2012-10-18 |
Schering Corporation |
Use of il-33 antagonists to treat fibrotic diseases
|
|
WO2011035065A1
(en)
|
2009-09-17 |
2011-03-24 |
Nektar Therapeutics |
Monoconjugated chitosans as delivery agents for small interfering nucleic acids
|
|
US20150025122A1
(en)
|
2009-10-12 |
2015-01-22 |
Larry J. Smith |
Methods and Compositions for Modulating Gene Expression Using Oligonucleotide Based Drugs Administered in vivo or in vitro
|
|
US8962584B2
(en)
|
2009-10-14 |
2015-02-24 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. |
Compositions for controlling Varroa mites in bees
|
|
US9799416B2
(en)
*
|
2009-11-06 |
2017-10-24 |
Terrapower, Llc |
Methods and systems for migrating fuel assemblies in a nuclear fission reactor
|
|
WO2011057171A1
(en)
|
2009-11-08 |
2011-05-12 |
Quark Pharmaceuticals, Inc. |
METHODS FOR DELIVERY OF siRNA TO THE SPINAL CORD AND THERAPIES ARISING THEREFROM
|
|
EP3305813B1
(en)
|
2009-11-11 |
2020-01-15 |
Ganymed Pharmaceuticals GmbH |
Antibodies specific for claudin 6 (cldn6)
|
|
CN102770529B
(zh)
|
2009-11-17 |
2018-06-05 |
Musc研究发展基金会 |
针对人核仁素的人单克隆抗体
|
|
CA2776568A1
(en)
|
2009-11-26 |
2011-06-03 |
Quark Pharmaceuticals, Inc. |
Sirna compounds comprising terminal substitutions
|
|
EP2505660B1
(en)
|
2009-11-27 |
2014-05-21 |
Japan Science And Technology Agency |
Method for screening of therapeutic agent for hyperlipemia
|
|
US8227444B2
(en)
*
|
2009-12-04 |
2012-07-24 |
Opko Ophthalmics, Llc |
Compositions and methods for inhibition of VEGF
|
|
CA2783372C
(en)
|
2009-12-07 |
2019-07-16 |
Muthiah Manoharan |
Compositions for nucleic acid delivery
|
|
CA2785996C
(en)
|
2009-12-07 |
2021-04-13 |
The Johns Hopkins University |
Sr-bi as a predictor of human female infertility and responsiveness to treatment
|
|
WO2011072082A2
(en)
|
2009-12-09 |
2011-06-16 |
Nitto Denko Corporation |
Modulation of hsp47 expression
|
|
EP2862929B1
(en)
|
2009-12-09 |
2017-09-06 |
Quark Pharmaceuticals, Inc. |
Compositions and methods for treating diseases, disorders or injury of the CNS
|
|
US8691227B2
(en)
|
2009-12-17 |
2014-04-08 |
Merck Sharp & Dohme Corp. |
Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
|
|
CA2784783C
(en)
|
2009-12-18 |
2021-07-20 |
Novartis Ag |
Organic compositions to treat hsf1-related diseases
|
|
AU2010330814B2
(en)
|
2009-12-18 |
2017-01-12 |
Acuitas Therapeutics Inc. |
Methods and compositions for delivery of nucleic acids
|
|
US20130023578A1
(en)
|
2009-12-31 |
2013-01-24 |
Samyang Biopharmaceuticals Corporation |
siRNA for inhibition of c-Met expression and anticancer composition containing the same
|
|
WO2011084193A1
(en)
|
2010-01-07 |
2011-07-14 |
Quark Pharmaceuticals, Inc. |
Oligonucleotide compounds comprising non-nucleotide overhangs
|
|
WO2011100131A2
(en)
|
2010-01-28 |
2011-08-18 |
Alnylam Pharmacuticals, Inc. |
Monomers and oligonucleotides comprising cycloaddition adduct(s)
|
|
WO2011094580A2
(en)
|
2010-01-28 |
2011-08-04 |
Alnylam Pharmaceuticals, Inc. |
Chelated copper for use in the preparation of conjugated oligonucleotides
|
|
BR112012019902A2
(pt)
|
2010-02-10 |
2019-09-24 |
Novartis Ag |
"método e compostos para o crescimento muscular"
|
|
IL265674B2
(en)
|
2010-03-24 |
2024-05-01 |
Phio Pharm Corp |
Rana disorder in cutaneous and fibrotic symptoms
|
|
RU2615143C2
(ru)
|
2010-03-24 |
2017-04-04 |
Адвирна |
Самодоставляющие PHKi соединения уменьшенного размера
|
|
US9095504B2
(en)
|
2010-03-24 |
2015-08-04 |
Rxi Pharmaceuticals Corporation |
RNA interference in ocular indications
|
|
US9102938B2
(en)
|
2010-04-01 |
2015-08-11 |
Alnylam Pharmaceuticals, Inc. |
2′ and 5′ modified monomers and oligonucleotides
|
|
CA2796459C
(en)
|
2010-04-16 |
2016-05-24 |
Salk Institute For Biological Studies |
Methods for treating metabolic disorders using fgf-1
|
|
WO2011131652A1
(en)
|
2010-04-19 |
2011-10-27 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Cxcl5 as a marker of hormone escape in prostate cancer
|
|
US9725479B2
(en)
|
2010-04-22 |
2017-08-08 |
Ionis Pharmaceuticals, Inc. |
5′-end derivatives
|
|
US20130260460A1
(en)
|
2010-04-22 |
2013-10-03 |
Isis Pharmaceuticals Inc |
Conformationally restricted dinucleotide monomers and oligonucleotides
|
|
US10913767B2
(en)
|
2010-04-22 |
2021-02-09 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising acyclic and abasic nucleosides and analogs
|
|
ES2699630T3
(es)
|
2010-04-23 |
2019-02-12 |
Cold Spring Harbor Laboratory |
Novedosos ARNhc diseñados estructuralmente
|
|
CA2797051C
(en)
|
2010-04-23 |
2021-01-12 |
Novartis Ag |
Organic compositions to treat beta-enac-related diseases
|
|
WO2012046149A1
(en)
|
2010-04-28 |
2012-04-12 |
Kimberly-Clark Worldwide, Inc. |
Method for increasing permeability of an epithelial barrier
|
|
US9522262B2
(en)
|
2010-04-28 |
2016-12-20 |
Kimberly-Clark Worldwide, Inc. |
Medical devices for delivery of siRNA
|
|
RU2570280C2
(ru)
|
2010-04-28 |
2015-12-10 |
Кимберли-Кларк Ворлдвайд, Инк. |
Композитная матрица микроигл, содержащая на поверхности наноструктуры
|
|
PT2563450T
(pt)
|
2010-04-28 |
2017-08-28 |
Kimberly Clark Co |
Dispositivo para entrega de medicação para a artrite reumatóide
|
|
KR20130107203A
(ko)
|
2010-05-04 |
2013-10-01 |
더 브리검 앤드 우먼즈 하스피털, 인크. |
섬유증의 검출 및 치료
|
|
WO2011150258A1
(en)
|
2010-05-26 |
2011-12-01 |
Selecta Biosciences, Inc. |
Dose selection of adjuvanted synthetic nanocarriers
|
|
US20130236968A1
(en)
|
2010-06-21 |
2013-09-12 |
Alnylam Pharmaceuticals, Inc. |
Multifunctional copolymers for nucleic acid delivery
|
|
US9006417B2
(en)
|
2010-06-30 |
2015-04-14 |
Protiva Biotherapeutics, Inc. |
Non-liposomal systems for nucleic acid delivery
|
|
EP2404936A1
(en)
|
2010-07-06 |
2012-01-11 |
Ganymed Pharmaceuticals AG |
Cancer therapy using CLDN6 target-directed antibodies in vivo
|
|
BR112013000651A2
(pt)
|
2010-07-09 |
2016-05-31 |
Exelixis Inc |
combinações de inibidores de cinase para o tratamento de câncer.
|
|
WO2012016188A2
(en)
|
2010-07-30 |
2012-02-02 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
|
US20130323269A1
(en)
|
2010-07-30 |
2013-12-05 |
Muthiah Manoharan |
Methods and compositions for delivery of active agents
|
|
JP5948327B2
(ja)
|
2010-07-30 |
2016-07-06 |
キュアヴァック アーゲー |
トランスフェクションおよび免疫刺激のためのジスルフィド架橋されたカチオン性成分との核酸の複合体形成
|
|
WO2012019132A2
(en)
|
2010-08-06 |
2012-02-09 |
Cell Signaling Technology, Inc. |
Anaplastic lymphoma kinase in kidney cancer
|
|
US20120052079A1
(en)
*
|
2010-08-10 |
2012-03-01 |
Dana-Farber Cancer Institute, Inc. |
Compositions, Kits, and Methods for Predicting Anti-Cancer Response to Anthracyclines
|
|
WO2012027206A1
(en)
|
2010-08-24 |
2012-03-01 |
Merck Sharp & Dohme Corp. |
SINGLE-STRANDED RNAi AGENTS CONTAINING AN INTERNAL, NON-NUCLEIC ACID SPACER
|
|
WO2012041959A1
(en)
|
2010-09-30 |
2012-04-05 |
University Of Zurich |
Treatment of b-cell lymphoma with microrna
|
|
EP2625267A2
(en)
|
2010-10-06 |
2013-08-14 |
Omnicyte Ltd. |
Culture method for culturing pluripotent cells comprising an inhibitor of mirna-181a*
|
|
AU2011311344B2
(en)
|
2010-10-08 |
2016-09-08 |
Mina Therapeutics Limited |
Short RNA molecules
|
|
US20140134231A1
(en)
|
2010-10-11 |
2014-05-15 |
Sanford-Burnham Medical Research Institute |
Mir-211 expression and related pathways in human melanoma
|
|
WO2012051491A1
(en)
|
2010-10-14 |
2012-04-19 |
The United States Of America, As Represented By The Secretary National Institutes Of Health |
Compositions and methods for controlling neurotropic viral pathogenesis by micro-rna targeting
|
|
EP2634253B1
(en)
|
2010-10-27 |
2016-05-11 |
Jichi Medical University |
Adeno-associated virus virions for transferring genes into neural cells
|
|
DK2632472T3
(en)
|
2010-10-29 |
2018-03-19 |
Sirna Therapeutics Inc |
RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA)
|
|
US8569220B2
(en)
|
2010-11-12 |
2013-10-29 |
Jelmar, Llc |
Hard surface cleaning composition
|
|
WO2012071436A1
(en)
|
2010-11-24 |
2012-05-31 |
Genentech, Inc. |
Method of treating autoimmune inflammatory disorders using il-23r loss-of-function mutants
|
|
WO2012072096A1
(en)
|
2010-12-03 |
2012-06-07 |
Biontech Ag |
Method for cellular rna expression
|
|
RS56419B1
(sr)
|
2010-12-03 |
2018-01-31 |
Biontech Rna Pharmaceuticals Gmbh |
Postupak za ćelijsku ekspresiju rnk
|
|
EP2649181B1
(en)
|
2010-12-06 |
2016-04-27 |
Quark Pharmaceuticals, Inc. |
Double stranded oligonucleotide compounds comprising positional modifications
|
|
WO2012090150A2
(en)
|
2010-12-27 |
2012-07-05 |
Compugen Ltd |
New cell-penetrating peptides and uses thereof
|
|
JP5902197B2
(ja)
|
2011-01-11 |
2016-04-13 |
アルニラム・ファーマシューティカルズ・インコーポレーテッド |
Peg化脂質および薬剤送達のためのそれらの使用
|
|
JP5952197B2
(ja)
|
2011-01-19 |
2016-07-13 |
協和発酵キリン株式会社 |
標的遺伝子の発現を抑制する組成物
|
|
MX2013008944A
(es)
|
2011-02-03 |
2014-01-08 |
Mirna Therapeutics Inc |
Mimeticos sinteticos de mir-124.
|
|
WO2012109495A1
(en)
|
2011-02-09 |
2012-08-16 |
Metabolic Solutions Development Company, Llc |
Cellular targets of thiazolidinediones
|
|
EP2681315B1
(en)
|
2011-03-03 |
2017-05-03 |
Quark Pharmaceuticals, Inc. |
Oligonucleotide modulators of the toll-like receptor pathway
|
|
US9796979B2
(en)
|
2011-03-03 |
2017-10-24 |
Quark Pharmaceuticals Inc. |
Oligonucleotide modulators of the toll-like receptor pathway
|
|
CN103492572A
(zh)
|
2011-03-03 |
2014-01-01 |
夸克医药公司 |
用于治疗肺疾病和损伤的组合物和方法
|
|
US10184942B2
(en)
|
2011-03-17 |
2019-01-22 |
University Of South Florida |
Natriuretic peptide receptor as a biomarker for diagnosis and prognosis of cancer
|
|
US9556448B2
(en)
|
2011-04-11 |
2017-01-31 |
Targeted Growth, Inc. |
Identification and the use of KRP mutants in plants
|
|
HUE028603T2
(en)
|
2011-05-13 |
2016-12-28 |
Ganymed Pharmaceuticals Ag |
Antibodies for treatment of cancer expressing claudin 6
|
|
WO2012164058A1
(en)
|
2011-06-01 |
2012-12-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for adjusting expression of mitochondrial genome by microrna
|
|
WO2012167173A1
(en)
|
2011-06-02 |
2012-12-06 |
The University Of Louisville Research Foundation, Inc. |
Anti-nucleolin agent-conjugated nanoparticles
|
|
US10196637B2
(en)
|
2011-06-08 |
2019-02-05 |
Nitto Denko Corporation |
Retinoid-lipid drug carrier
|
|
TWI658830B
(zh)
|
2011-06-08 |
2019-05-11 |
日東電工股份有限公司 |
Hsp47表現調控強化用類視色素脂質體
|
|
SG10201604726YA
(en)
|
2011-06-10 |
2016-07-28 |
Temasek Life Sciences Lab Ltd |
Genetic manipulation and expression systems for pucciniomycotina and ustilaginomycotina subphyla
|
|
WO2013003697A1
(en)
|
2011-06-30 |
2013-01-03 |
Trustees Of Boston University |
Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1)
|
|
US9120858B2
(en)
|
2011-07-22 |
2015-09-01 |
The Research Foundation Of State University Of New York |
Antibodies to the B12-transcobalamin receptor
|
|
CN104011069A
(zh)
|
2011-08-01 |
2014-08-27 |
塔夫茨医学中心有限公司 |
心力衰竭及相关病症的治疗
|
|
EP3521432A1
(en)
|
2011-09-02 |
2019-08-07 |
Arrowhead Pharmaceuticals, Inc. |
Organic compositions to treat hsf1-related diseases
|
|
US9644241B2
(en)
|
2011-09-13 |
2017-05-09 |
Interpace Diagnostics, Llc |
Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease
|
|
AU2012315965A1
(en)
|
2011-09-27 |
2014-04-03 |
Alnylam Pharmaceuticals, Inc. |
Di-aliphatic substituted PEGylated lipids
|
|
CN104364390B
(zh)
|
2011-10-14 |
2016-08-24 |
俄亥俄州立大学 |
与卵巢癌相关的方法和材料
|
|
CN104039382B
(zh)
|
2011-10-27 |
2018-01-12 |
金伯利-克拉克环球有限公司 |
高粘度生物活性剂的经皮递送
|
|
WO2013060894A1
(en)
|
2011-10-27 |
2013-05-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment and diagnosis of atherosclerosis
|
|
US20170246439A9
(en)
|
2011-10-27 |
2017-08-31 |
Kimberly-Clark Worldwide, Inc. |
Increased Bioavailability of Transdermally Delivered Agents
|
|
PL3542851T3
(pl)
|
2011-10-27 |
2022-04-25 |
Sorrento Therapeutics, Inc. |
Wszczepialne urządzenia do dostarczania środków biologicznie czynnych
|
|
SG11201401648RA
(en)
|
2011-11-03 |
2014-05-29 |
Quark Pharmaceuticals Inc |
Methods and compositions for neuroprotection
|
|
US20140323549A1
(en)
|
2011-11-08 |
2014-10-30 |
Quark Pharmaceuticals, Inc. |
Methods and compositions for treating diseases, disorders or injury of the nervous system
|
|
CA2860676A1
(en)
|
2012-01-09 |
2013-07-18 |
Novartis Ag |
Organic compositions to treat beta-catenin-related diseases
|
|
WO2013112458A1
(en)
|
2012-01-24 |
2013-08-01 |
Beth Israel Deaconess Medical Center, Inc. |
Novel chrebp isoforms and methods using the same
|
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
|
MX367842B
(es)
|
2012-02-07 |
2019-09-09 |
Global Bio Therapeutics Inc |
Método compartimentado de administración de ácidos nucleicos y composiciones y usos del mismo.
|
|
EP2822571A4
(en)
|
2012-02-16 |
2016-03-09 |
Penn State Res Found |
MODULATORS OF ACYL-COA LYSOCARDIOLIPINE ACYLTRANSFERASE 1 (ALCAT1) AND USES THEREOF
|
|
US9193971B2
(en)
|
2012-04-10 |
2015-11-24 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods for the treatment of nonalcoholic steatohepatitis
|
|
WO2013153139A1
(en)
|
2012-04-11 |
2013-10-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment and diagnosis of acute leukemia
|
|
DK2838998T3
(en)
|
2012-04-18 |
2018-01-15 |
Cell Signaling Technology Inc |
EGFR AND ROS1 IN CANCER
|
|
US10100321B2
(en)
|
2012-04-19 |
2018-10-16 |
Temasek Life Sciences Laboratory Limited |
Methods for increasing cotton fiber length
|
|
US20140108091A1
(en)
*
|
2012-04-19 |
2014-04-17 |
FullCircle CRM |
Method and System for Attributing Metrics in a CRM System
|
|
EP2844261B1
(en)
|
2012-05-02 |
2018-10-17 |
Sirna Therapeutics, Inc. |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
|
|
WO2013170960A1
(en)
|
2012-05-16 |
2013-11-21 |
Silence Therapeutics Ag |
Use of vegfr1 as a biomarker for pkn3 inhibitor administration
|
|
US9869519B2
(en)
*
|
2012-07-12 |
2018-01-16 |
Google Inc. |
Thermosiphon systems for electronic devices
|
|
CA2878314A1
(en)
|
2012-07-16 |
2014-01-23 |
Kyowa Hakko Kirin Co., Ltd. |
Rnai pharmaceutical composition for suppressing expression of kras gene
|
|
WO2014018375A1
(en)
|
2012-07-23 |
2014-01-30 |
Xenon Pharmaceuticals Inc. |
Cyp8b1 and uses thereof in therapeutic and diagnostic methods
|
|
WO2014072061A1
(en)
|
2012-11-09 |
2014-05-15 |
Biontech Ag |
Method for cellular rna expression
|
|
WO2014071963A1
(en)
|
2012-11-09 |
2014-05-15 |
Biontech Ag |
Method for cellular rna expression
|
|
ES2780674T3
(es)
|
2012-11-15 |
2020-08-26 |
Apellis Pharmaceuticals Inc |
Análogos de compstatina de acción prolongada y composiciones y métodos relacionados
|
|
WO2014152391A1
(en)
|
2013-03-15 |
2014-09-25 |
Apellis Pharmaceuticals, Inc. |
Cell-penetrating compstatin analogs and uses thereof
|
|
CA2918194C
(en)
|
2013-03-27 |
2022-12-06 |
The General Hospital Corporation |
Methods and agents for treating alzheimer's disease
|
|
CN104211814A
(zh)
|
2013-05-29 |
2014-12-17 |
三星电子株式会社 |
用于消耗靶膜蛋白的组合物
|
|
MX394708B
(es)
*
|
2013-06-19 |
2025-03-24 |
Rnaissance Ag Llc |
Composiciones y metodos que usan capsides resistentes a hidrolasas.
|
|
AU2014302038B2
(en)
|
2013-06-25 |
2019-11-14 |
Epiaxis Therapeutics Pty Ltd |
Methods and compositions for modulating cancer stem cells
|
|
MX359191B
(es)
|
2013-07-19 |
2018-09-18 |
Monsanto Technology Llc |
Composiciones y métodos para controlar leptinotarsa.
|
|
WO2015014376A1
(en)
|
2013-07-31 |
2015-02-05 |
Biontech Ag |
Diagnosis and therapy of cancer involving cancer stem cells
|
|
CN105452465B
(zh)
|
2013-07-31 |
2019-06-21 |
奇比艾企业有限公司 |
鞘脂-聚烷基胺-寡核苷酸化合物
|
|
WO2015015498A1
(en)
|
2013-07-31 |
2015-02-05 |
Qbi Enterprises Ltd. |
Methods of use of sphingolipid polyalkylamine oligonucleotide compounds
|
|
MX378673B
(es)
|
2013-08-08 |
2025-03-10 |
Global Bio Therapeutics Inc |
Dispositivo de sujecion para procedimientos minimamente invasivos y usos del mismo.
|
|
SG11201510746WA
(en)
|
2013-08-21 |
2016-03-30 |
Curevac Ag |
Respiratory syncytial virus (rsv) vaccine
|
|
CA2923765C
(en)
|
2013-09-18 |
2021-06-29 |
University Of Canberra |
Stem cell modulation ii
|
|
TWI669393B
(zh)
*
|
2013-10-02 |
2019-08-21 |
艾爾妮蘭製藥公司 |
抑制lect2基因表現之組合物及方法
|
|
CN105764511B
(zh)
|
2013-10-04 |
2019-01-11 |
艾普托斯生物科学公司 |
用于治疗癌症的组合物和方法
|
|
EP3068407A1
(en)
|
2013-11-11 |
2016-09-21 |
Sirna Therapeutics, Inc. |
Systemic delivery of myostatin short interfering nucleic acids (sina) conjugated to a lipophilic moiety
|
|
CN106061488B
(zh)
|
2013-12-02 |
2021-04-09 |
菲奥医药公司 |
癌症的免疫治疗
|
|
AU2014360314B2
(en)
|
2013-12-06 |
2018-04-26 |
Dicerna Pharmaceuticals, Inc. |
Methods and compositions for the specific inhibition of transthyretin (TTR) by double-stranded RNA
|
|
WO2015086828A1
(en)
|
2013-12-12 |
2015-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the prevention and treatment of diabetic cardiomyopathy using mir-424/322
|
|
JPWO2015108162A1
(ja)
|
2014-01-17 |
2017-03-23 |
協和発酵キリン株式会社 |
β2GPIの発現を抑制する核酸
|
|
WO2015136001A1
(en)
|
2014-03-11 |
2015-09-17 |
Cellectis |
Method for generating t-cells compatible for allogenic transplantation
|
|
AU2015231294B2
(en)
|
2014-03-18 |
2020-10-29 |
University Of Massachusetts |
rAAV-based compositions and methods for treating amyotrophic lateral sclerosis
|
|
US9856475B2
(en)
|
2014-03-25 |
2018-01-02 |
Arcturus Therapeutics, Inc. |
Formulations for treating amyloidosis
|
|
JP6771387B2
(ja)
|
2014-03-25 |
2020-10-21 |
アークトゥラス・セラピューティクス・インコーポレイテッドArcturus Therapeutics,Inc. |
遺伝子サイレンシング用トランスサイレチン対立遺伝子選択的unaオリゴマー
|
|
CA2946719C
(en)
|
2014-03-25 |
2023-09-26 |
Arcturus Therapeutics, Inc. |
Una oligomers having reduced off-target effects in gene silencing
|
|
EP3420809A1
(en)
|
2014-04-01 |
2019-01-02 |
Monsanto Technology LLC |
Compositions and methods for controlling insect pests
|
|
WO2015149944A2
(en)
|
2014-04-01 |
2015-10-08 |
Curevac Gmbh |
Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant
|
|
CA2947270A1
(en)
|
2014-04-28 |
2015-11-05 |
Rxi Pharmaceuticals Corporation |
Methods for treating cancer using nucleic acids targeting mdm2 or mycn
|
|
HRP20251099T1
(hr)
|
2014-06-09 |
2025-11-07 |
Ultragenyx Pharmaceutical Inc. |
Učinkovita i djelotvorna kontrola serumskog fosfata za optimalno stvaranje kostiju
|
|
TW201620526A
(zh)
|
2014-06-17 |
2016-06-16 |
愛羅海德研究公司 |
用於抑制α-1抗胰蛋白酶基因表現之組合物及方法
|
|
JP6264329B2
(ja)
|
2014-06-18 |
2018-01-24 |
トヨタ自動車株式会社 |
車両用駆動制御装置
|
|
WO2016018887A1
(en)
|
2014-07-29 |
2016-02-04 |
Monsanto Technology Llc |
Compositions and methods for controlling insect pests
|
|
AU2015309686B2
(en)
|
2014-08-25 |
2020-05-14 |
Epiaxis Therapeutics Pty Ltd |
Compositions for modulating cancer stem cells and uses therefor
|
|
KR102506169B1
(ko)
|
2014-09-05 |
2023-03-08 |
피오 파마슈티칼스 코프. |
Tyr 또는 mmp1을 표적화하는 핵산을 사용한 노화 및 피부 장애의 치료 방법
|
|
US20180010132A1
(en)
|
2014-09-11 |
2018-01-11 |
Novartis Ag |
Inhibition of prmt5 to treat mtap-deficiency-related diseases
|
|
KR102473092B1
(ko)
|
2014-09-15 |
2022-12-01 |
칠드런'즈 메디컬 센터 코포레이션 |
히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물
|
|
AU2015320748A1
(en)
|
2014-09-25 |
2017-04-20 |
Cold Spring Harbor Laboratory |
Treatment of Rett Syndrome
|
|
US20160101128A1
(en)
|
2014-10-10 |
2016-04-14 |
Idera Pharmaceuticals, Inc. |
Treatment of cancer using tlr9 agonist with checkpoint inhibitors
|
|
WO2016057693A1
(en)
|
2014-10-10 |
2016-04-14 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for inhalation delivery of conjugated oligonucleotide
|
|
EP3206749B1
(en)
|
2014-10-14 |
2021-09-08 |
The Regents of the University of California |
The cdk9 and brd4 inhibitors flavopiridol and jq1 to inhibit cartilage inflammation
|
|
WO2016062323A1
(en)
|
2014-10-20 |
2016-04-28 |
Biontech Ag |
Methods and compositions for diagnosis and treatment of cancer
|
|
WO2016064347A1
(en)
|
2014-10-22 |
2016-04-28 |
Temasek Life Sciences Laboratory Limited |
Terpene synthases from ylang ylang (cananga odorata var. fruticosa)
|
|
JOP20200092A1
(ar)
|
2014-11-10 |
2017-06-16 |
Alnylam Pharmaceuticals Inc |
تركيبات iRNA لفيروس الكبد B (HBV) وطرق لاستخدامها
|
|
EP3218497A1
(en)
|
2014-11-12 |
2017-09-20 |
NMC Inc. |
Transgenic plants with engineered redox sensitive modulation of photosynthetic antenna complex pigments and methods for making the same
|
|
RU2020108189A
(ru)
|
2014-11-14 |
2020-03-11 |
Вояджер Терапьютикс, Инк. |
Композиции и способы лечения бокового амиотрофического склероза (als)
|
|
MX2017006217A
(es)
|
2014-11-14 |
2018-05-02 |
Voyager Therapeutics Inc |
Polinucleotidos moduladores.
|
|
WO2016089883A1
(en)
|
2014-12-01 |
2016-06-09 |
Novartis Ag |
Compositions and methods for diagnosis and treatment of prostate cancer
|
|
PL3227310T3
(pl)
|
2014-12-03 |
2020-02-28 |
Glycomimetics, Inc. |
Heterodwufunkcyjne inhibitory selektyn E i receptorów chemokinowych CXCR4”
|
|
PL3256589T3
(pl)
|
2015-01-22 |
2022-02-21 |
Monsanto Technology Llc |
Kompozycje i sposoby kontrolowania leptinotarsa
|
|
CA2978431C
(en)
|
2015-03-02 |
2023-10-24 |
180 Therapeutics Lp |
Method of treating a localized fibrotic disorder using a tnf receptor 2 antagonist
|
|
WO2016145005A1
(en)
|
2015-03-09 |
2016-09-15 |
University Of Kentucky Research Foundation |
Rna nanoparticles for brain tumor treatment
|
|
US10519447B2
(en)
|
2015-04-01 |
2019-12-31 |
Arcturus Therapeutics, Inc. |
Therapeutic UNA oligomers and uses thereof
|
|
WO2016164746A1
(en)
|
2015-04-08 |
2016-10-13 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of the lect2 gene
|
|
WO2016179394A1
(en)
|
2015-05-05 |
2016-11-10 |
Malik Mohammad Tariq |
Anti-nucleolin agent-conjugated nanoparticles as radio-sensitizers and mri and/or x-ray contrast agents
|
|
AU2016269839B2
(en)
|
2015-06-03 |
2021-07-08 |
The University Of Queensland |
Mobilizing agents and uses therefor
|
|
ES3049133T3
(en)
|
2015-06-03 |
2025-12-15 |
Aelan Cell Tech Inc |
Companion methods or il-2-based therapies and mesenchymal stem cell-based therapies
|
|
EP3302525A2
(en)
|
2015-06-05 |
2018-04-11 |
Novartis AG |
Methods and compositions for diagnosing, treating, and monitoring treatment of shank3 deficiency associated disorders
|
|
US10808247B2
(en)
|
2015-07-06 |
2020-10-20 |
Phio Pharmaceuticals Corp. |
Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach
|
|
KR20180026739A
(ko)
|
2015-07-06 |
2018-03-13 |
알엑스아이 파마슈티칼스 코포레이션 |
슈퍼옥시드 디스뮤타제 1 (sod1)을 표적화하는 핵산 분자
|
|
WO2017015671A1
(en)
|
2015-07-23 |
2017-01-26 |
Arcturus Therapeutics, Inc. |
Compositions for treating amyloidosis
|
|
EP3340967B1
(en)
|
2015-08-24 |
2024-05-22 |
Halo-Bio Rnai Therapeutics, Inc. |
Polynucleotide nanoparticles for the modulation of gene expression and uses thereof
|
|
JP6638072B2
(ja)
|
2015-09-15 |
2020-01-29 |
サムヤン バイオファーマシューティカルズ コーポレイションSamyang Biopharmaceuticals Corporation |
アニオン性薬物含有医薬組成物及びその製造方法
|
|
US10358497B2
(en)
|
2015-09-29 |
2019-07-23 |
Amgen Inc. |
Methods of treating cardiovascular disease with an ASGR inhibitor
|
|
FI3359555T3
(fi)
|
2015-10-07 |
2024-03-20 |
Apellis Pharmaceuticals Inc |
Annostusohjeet
|
|
US11021707B2
(en)
|
2015-10-19 |
2021-06-01 |
Phio Pharmaceuticals Corp. |
Reduced size self-delivering nucleic acid compounds targeting long non-coding RNA
|
|
ES2901102T3
(es)
|
2015-12-18 |
2022-03-21 |
Samyang Holdings Corp |
Método para preparar una micela polimérica que contiene fármaco aniónico
|
|
WO2017112887A1
(en)
|
2015-12-22 |
2017-06-29 |
Provivi, Inc. |
Method for managing resistance to insecticidal traits and chemicals using pheromones
|
|
WO2017151708A1
(en)
|
2016-03-02 |
2017-09-08 |
Glycomimetics, Inc. |
Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
|
|
EP3423568A4
(en)
|
2016-03-04 |
2019-11-13 |
University Of Louisville Research Foundation, Inc. |
METHOD AND COMPOSITIONS FOR EX-VIVO REPRODUCTION OF VERY SMALL EMBRYONAL STEM CELLS (VSELS)
|
|
MX2018009854A
(es)
|
2016-03-07 |
2018-11-09 |
Arrowhead Pharmaceuticals Inc |
Ligandos dirigidos para compuestos terapeuticos.
|
|
AU2017234163B2
(en)
|
2016-03-15 |
2023-01-19 |
Mersana Therapeutics, Inc. |
NaPi2b-targeted antibody-drug conjugates and methods of use thereof
|
|
WO2017173301A1
(en)
|
2016-04-01 |
2017-10-05 |
Avidity Biosciences Llc |
Egfr nucleic acids and uses thereof
|
|
MA45470A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques kras et leurs utilisations
|
|
EP3436582B1
(en)
|
2016-04-01 |
2021-10-13 |
Avidity Biosciences, Inc. |
Beta-catenin nucleic acids and uses thereof
|
|
KR102775461B1
(ko)
|
2016-04-01 |
2025-02-28 |
어비디티 바이오사이언시스 인크. |
핵산-폴리펩타이드 조성물 및 이의 용도
|
|
US9988641B2
(en)
|
2016-04-05 |
2018-06-05 |
Corn Products Development, Inc. |
Compositions and methods for producing starch with novel functionality
|
|
KR102378404B1
(ko)
|
2016-04-22 |
2022-03-24 |
비온테크 에스이 |
단일가닥 rna 제공 방법
|
|
CN116333057A
(zh)
|
2016-05-13 |
2023-06-27 |
4D分子治疗有限公司 |
腺相关病毒变体衣壳和其使用方法
|
|
BR112018073472A2
(pt)
|
2016-05-18 |
2019-08-27 |
Voyager Therapeutics, Inc. |
composições e métodos de tratamento da doença de huntington
|
|
AU2017267665C1
(en)
|
2016-05-18 |
2023-10-05 |
Voyager Therapeutics, Inc. |
Modulatory polynucleotides
|
|
PT109454A
(pt)
|
2016-06-14 |
2017-12-14 |
Phyzat Biopharmaceuticals Lda |
Ácidos nucleicos de interferência e composições que os compreendem
|
|
BR112019000015A2
(pt)
|
2016-06-30 |
2019-04-24 |
Oncorus, Inc. |
distribuição por vírus oncolítico pseudotipado de polipeptídeos terapêuticos
|
|
US20190367930A1
(en)
|
2016-07-29 |
2019-12-05 |
Danmarks Tekniske Universitet |
Methods for decoupling cell growth from production of biochemicals and recombinant polypeptides
|
|
JP2019524791A
(ja)
|
2016-08-08 |
2019-09-05 |
グリコミメティクス, インコーポレイテッド |
E−セレクチンの阻害剤もしくはcxcr4の阻害剤との、またはe−セレクチンおよびcxcr4両方のヘテロ二機能性阻害剤とのt細胞チェックポイント阻害剤の組み合わせ
|
|
CN116832169A
(zh)
|
2016-09-02 |
2023-10-03 |
箭头药业股份有限公司 |
靶向配体
|
|
US10933081B2
(en)
|
2016-09-21 |
2021-03-02 |
Alnylam Pharmaceuticals, Inc. |
Myostatin iRNA compositions and methods of use thereof
|
|
CN109890421B
(zh)
|
2016-10-07 |
2023-10-20 |
糖模拟物有限公司 |
高效的多聚体e-选择蛋白拮抗剂
|
|
WO2018083606A1
(en)
|
2016-11-01 |
2018-05-11 |
Novartis Ag |
Methods and compositions for enhancing gene editing
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
MX2019008252A
(es)
|
2017-01-10 |
2019-09-06 |
Arrowhead Pharmaceuticals Inc |
Agentes de interferencia de acido ribonucleico (iarn) de alfa-1 antitripsina (aat), composiciones que incluyen agentes de iarn aat y metodos de uso.
|
|
JP7215716B2
(ja)
|
2017-01-13 |
2023-01-31 |
学校法人自治医科大学 |
肝臓ゲノム上の凝固関連因子遺伝子を破壊するためのaavベクター
|
|
WO2018160538A1
(en)
|
2017-02-28 |
2018-09-07 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
|
WO2018164186A1
(ja)
|
2017-03-09 |
2018-09-13 |
協和発酵キリン株式会社 |
Masp2の発現を抑制する核酸
|
|
US11197877B2
(en)
|
2017-03-15 |
2021-12-14 |
Glycomimetics. Inc. |
Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists
|
|
EP3607971A4
(en)
|
2017-04-05 |
2021-01-06 |
National University Corporation Chiba University |
SWI / SNF COMPLEX FUNCTION INHIBITOR
|
|
US11040107B2
(en)
|
2017-04-07 |
2021-06-22 |
Apellis Pharmaceuticals, Inc. |
Dosing regimens and related compositions and methods
|
|
US11324820B2
(en)
|
2017-04-18 |
2022-05-10 |
Alnylam Pharmaceuticals, Inc. |
Methods for the treatment of subjects having a hepatitis b virus (HBV) infection
|
|
EP3612152A4
(en)
|
2017-04-19 |
2021-02-17 |
Phio Pharmaceuticals Corp. |
TOPICAL ADMINISTRATION OF NUCLEIC ACID COMPOUNDS
|
|
CN106973864A
(zh)
*
|
2017-04-25 |
2017-07-25 |
遵义医学院 |
一种适用于白背飞虱注射法rna干扰实验的饲养装置及其使用方法
|
|
CN111108198A
(zh)
|
2017-05-05 |
2020-05-05 |
沃雅戈治疗公司 |
治疗亨廷顿病的组合物和方法
|
|
CA3061652A1
(en)
|
2017-05-05 |
2018-11-08 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
EP3622073A4
(en)
|
2017-05-09 |
2021-01-06 |
University of Massachusetts |
METHOD FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
|
|
KR20200014320A
(ko)
|
2017-05-31 |
2020-02-10 |
쿄와 기린 가부시키가이샤 |
Apcs의 발현을 억제하는 핵산
|
|
WO2019016772A2
(en)
|
2017-07-21 |
2019-01-24 |
Novartis Ag |
COMPOSITIONS AND METHODS FOR TREATING CANCER
|
|
BR112020005436B1
(pt)
|
2017-09-20 |
2022-08-02 |
4D Molecular Therapeutics Inc |
Proteína do capsídeo de variante do vírus adenoassociado, virion do aav recombinante (raav) infeccioso, composições, composições farmacêuticas e usos de virion de raav ou de composições farmacêuticas
|
|
JP7397488B2
(ja)
|
2017-09-22 |
2023-12-13 |
ユニバーシティ オブ マサチューセッツ |
Sod1二重発現ベクターおよびその使用
|
|
US20200237799A1
(en)
|
2017-10-16 |
2020-07-30 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis (als)
|
|
CN111479924B
(zh)
|
2017-10-16 |
2024-06-14 |
沃雅戈治疗公司 |
肌萎缩性侧索硬化症(als)的治疗
|
|
MY201698A
(en)
|
2017-10-20 |
2024-03-13 |
Dicerna Pharmaceuticals Inc |
Methods for treating hepatitis b infection
|
|
FI3717636T3
(fi)
|
2017-11-27 |
2023-06-01 |
4D Molecular Therapeutics Inc |
Adenoassosioidun viruksen kapsidivariantteja ja käyttö angiogeneesin estämisessä
|
|
US11638760B2
(en)
|
2017-11-27 |
2023-05-02 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
US11712446B2
(en)
|
2017-11-30 |
2023-08-01 |
Glycomimetics, Inc. |
Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
|
|
CN118638787A
(zh)
*
|
2017-12-06 |
2024-09-13 |
艾维迪提生物科学公司 |
治疗肌萎缩和强直性肌营养不良的组合物和方法
|
|
WO2019118938A1
(en)
|
2017-12-15 |
2019-06-20 |
Apellis Pharmaceuticals, Inc. |
Dosing regimens and related compositions and methods
|
|
JP2021506883A
(ja)
|
2017-12-21 |
2021-02-22 |
メルサナ セラピューティクス インコーポレイテッド |
ピロロベンゾジアゼピン抗体結合体
|
|
US11865081B2
(en)
|
2017-12-29 |
2024-01-09 |
Virogin Biotech Canada Ltd. |
Oncolytic viral delivery of therapeutic polypeptides
|
|
EP3732186A1
(en)
|
2017-12-29 |
2020-11-04 |
GlycoMimetics, Inc. |
Heterobifunctional inhibitors of e-selectin and galectin-3
|
|
JP2021511042A
(ja)
|
2018-01-16 |
2021-05-06 |
ディセルナ ファーマシューティカルズ インコーポレイテッド |
Aldh2発現を阻害するための組成物及び方法
|
|
KR20200128025A
(ko)
|
2018-03-05 |
2020-11-11 |
글리코미메틱스, 인크. |
급성 골수성 백혈병 및 관련 병태의 치료 방법
|
|
US20210123016A1
(en)
|
2018-05-02 |
2021-04-29 |
Novartis Ag |
Regulators of human pluripotent stem cells and uses thereof
|
|
BR112021000538A2
(pt)
|
2018-07-13 |
2021-04-06 |
F. Hoffmann-La Roche Ag |
Oligonucleotídeos para modular a expressão de rtel1
|
|
US12188040B2
(en)
|
2018-07-30 |
2025-01-07 |
Gene Therapy Research Institution Co., Ltd. |
Method for enhancing gene expression using AAV vector
|
|
MX2021001056A
(es)
|
2018-08-13 |
2021-04-12 |
Alnylam Pharmaceuticals Inc |
Composiciones de agente de acido ribonucleico bicatenario (arnbc) de virus de la hepatitis b (vhb) y metodos de uso de las mismas.
|
|
KR20210084546A
(ko)
|
2018-10-29 |
2021-07-07 |
메르사나 테라퓨틱스, 인코포레이티드 |
펩티드 함유 링커를 갖는 시스테인 조작된 항체-약물 접합체
|
|
WO2020128816A2
(en)
|
2018-12-20 |
2020-06-25 |
Pfizer Inc. |
Pharmaceutical compositions and methods comprising a combination of a benzoxazole transthyretin stabilizer and an additional therapeutic agent
|
|
US11845771B2
(en)
|
2018-12-27 |
2023-12-19 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of E-selectin and galectin-3
|
|
AU2020221892A1
(en)
|
2019-02-12 |
2021-08-19 |
Dicerna Pharmaceuticals, Inc. |
Methods and compositions for inhibiting expression of CYP27A1
|
|
US12215382B2
(en)
|
2019-03-01 |
2025-02-04 |
The General Hospital Corporation |
Liver protective MARC variants and uses thereof
|
|
CA3135402A1
(en)
|
2019-04-04 |
2020-10-08 |
Dicerna Pharmaceuticals, Inc. |
Compositions and methods for inhibiting gene expression in the central nervous system
|
|
JP2022529917A
(ja)
|
2019-04-18 |
2022-06-27 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
ガンの処置及び予後のための方法
|
|
MX2022000134A
(es)
*
|
2019-07-02 |
2022-05-19 |
Na Vaccine Inst |
Nuevo ácido ribonucleico y composición farmacéutica basada en el mismo.
|
|
WO2021009805A1
(ja)
|
2019-07-12 |
2021-01-21 |
株式会社遺伝子治療研究所 |
ヒト肝臓への遺伝子導入のためのアデノ随伴ウイルスビリオン
|
|
EP4081217A1
(en)
|
2019-12-24 |
2022-11-02 |
F. Hoffmann-La Roche AG |
Pharmaceutical combination of antiviral agents targeting hbv and/or an immune modulator for treatment of hbv
|
|
EP4081639A1
(en)
|
2019-12-24 |
2022-11-02 |
F. Hoffmann-La Roche AG |
Pharmaceutical combination of a therapeutic oligonucleotide targeting hbv and a tlr7 agonist for treatment of hbv
|
|
IL296549A
(en)
|
2020-03-18 |
2022-11-01 |
Dicerna Pharmaceuticals Inc |
Compositions and methods for inhibiting angptl3 expression
|
|
AU2021237465A1
(en)
|
2020-03-19 |
2022-10-13 |
Avidity Biosciences, Inc. |
Compositions and methods of treating Facioscapulohumeral muscular dystrophy
|
|
JP2023524639A
(ja)
|
2020-04-22 |
2023-06-13 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
患者特異的免疫療法用細胞の製造調整システム及び調整方法
|
|
KR20230026985A
(ko)
|
2020-04-27 |
2023-02-27 |
4디 몰레큘러 테라퓨틱스 아이엔씨. |
폐 전달을 위한 아데노-관련 변이체, 제제 및 방법
|
|
US20210332364A1
(en)
|
2020-04-28 |
2021-10-28 |
Phyzat Biopharmaceuticals, Lda |
siNA MOLECULES, METHODS OF PRODUCTION AND USES THEREOF
|
|
WO2021228585A1
(en)
|
2020-05-09 |
2021-11-18 |
Phyzat Biopharmaceuticals, Lda |
Sina molecules, methods of production and uses thereof
|
|
US20230212572A1
(en)
|
2020-06-09 |
2023-07-06 |
Roche Innovation Center Copenhagen A/S |
Guanosine Analogues for Use in Therapeutics Polynucleotides
|
|
AU2021307452A1
(en)
|
2020-07-15 |
2023-02-09 |
Biogen Ma Inc. |
Implantable cranial medical device
|
|
TW202221120A
(zh)
|
2020-08-04 |
2022-06-01 |
美商黛瑟納製藥公司 |
用於治療代謝症候群之組成物及方法
|
|
CA3187220A1
(en)
|
2020-08-04 |
2022-02-10 |
Dicerna Pharmaceuticals, Inc. |
Systemic delivery of oligonucleotides
|
|
JP2023536999A
(ja)
|
2020-08-05 |
2023-08-30 |
エフ. ホフマン-ラ ロシュ アーゲー |
B型肝炎患者のオリゴヌクレオチド処置
|
|
JP7476422B2
(ja)
|
2020-08-05 |
2024-04-30 |
ディセルナ ファーマシューティカルズ インコーポレイテッド |
Lpa発現を阻害するための組成物及び方法
|
|
US20230372397A1
(en)
|
2020-10-06 |
2023-11-23 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
|
WO2022107106A2
(en)
|
2020-11-23 |
2022-05-27 |
Phyzat Biopharmaceuticals, Lda |
Sina molecules, methods of production and uses thereof
|
|
US11591544B2
(en)
|
2020-11-25 |
2023-02-28 |
Akagera Medicines, Inc. |
Ionizable cationic lipids
|
|
CN112511569B
(zh)
*
|
2021-02-07 |
2021-05-11 |
杭州筋斗腾云科技有限公司 |
网络资源访问请求的处理方法、系统及计算机设备
|
|
US12129470B2
(en)
|
2021-02-09 |
2024-10-29 |
The Texas A&M University System |
Methods and compositions related to RNA-targeted Rho small GTPase RND3/RhoE therapy
|
|
KR20240032711A
(ko)
|
2021-03-25 |
2024-03-12 |
이오반스 바이오테라퓨틱스, 인크. |
T-세포 공배양 효능 검정 및 세포 치료제와 함께 사용하기 위한 방법 및 조성물
|
|
WO2022218941A2
(en)
|
2021-04-12 |
2022-10-20 |
Boehringer Ingelheim International Gmbh |
Compositions and methods for inhibiting ketohexokinase (khk)
|
|
EP4322925A2
(en)
|
2021-04-12 |
2024-02-21 |
BioNTech SE |
Rna compositions comprising a buffer substance and methods for preparing, storing and using the same
|
|
KR20230171431A
(ko)
|
2021-04-14 |
2023-12-20 |
다이서나 파마수이티컬, 인크. |
Pnpla3 발현을 조절하기 위한 조성물 및 방법
|
|
CA3213775A1
(en)
|
2021-04-19 |
2022-10-27 |
Utsav SAXENA |
Compositions and methods for inhibiting nuclear receptor subfamily 1 group h member 3 (nr1h3) expression
|
|
JPWO2022224372A1
(enExample)
|
2021-04-21 |
2022-10-27 |
|
|
|
AR125992A1
(es)
|
2021-05-28 |
2023-08-30 |
Novo Nordisk As |
Composiciones y métodos para inhibir la expresión del componente 1 de reducción de amidoxima mitocondrial (marc1)
|
|
CN117157309A
(zh)
|
2021-05-28 |
2023-12-01 |
上海瑞宏迪医药有限公司 |
衣壳变异的重组腺相关病毒及其应用
|
|
CN117897483A
(zh)
|
2021-08-25 |
2024-04-16 |
戴瑟纳制药公司 |
用于抑制α-1抗胰蛋白酶表达的组合物和方法
|
|
IL312635A
(en)
|
2021-11-11 |
2024-07-01 |
Hoffmann La Roche |
Pharmaceutical combinations for treatment of hbv
|
|
US12234456B2
(en)
|
2021-12-01 |
2025-02-25 |
Dicerna Pharmaceuticals, Inc. |
Compositions and methods for modulating APOC3 expression
|
|
US20250312484A1
(en)
|
2021-12-06 |
2025-10-09 |
Jichi Medical University |
Recombinant adeno-associated virus vector for treatment of iron-accumulating neurodegenerative diseases
|
|
WO2023118546A2
(en)
|
2021-12-23 |
2023-06-29 |
Boehringer Ingelheim International Gmbh |
METHODS AND MOLECULES FOR RNA INTERFERENCE (RNAi)
|
|
WO2023193892A1
(en)
|
2022-04-05 |
2023-10-12 |
BioNTech SE |
Nucleic acid compositions comprising an inorganic polyphosphate and methods for preparing, storing and using the same
|
|
KR20250005108A
(ko)
|
2022-04-15 |
2025-01-09 |
다이서나 파마수이티컬, 인크. |
Scap 활성을 조절하기 위한 조성물 및 방법
|
|
JP2025516677A
(ja)
|
2022-05-12 |
2025-05-30 |
ディセルナ ファーマシューティカルズ インコーポレイテッド |
Maptの発現を阻害するための組成物及び方法
|
|
KR20250024534A
(ko)
|
2022-05-13 |
2025-02-18 |
다이서나 파마수이티컬, 인크. |
Snca 발현을 억제하기 위한 조성물 및 방법
|
|
KR20250031230A
(ko)
|
2022-05-25 |
2025-03-06 |
아카제라 메디신즈, 인크. |
핵산 전달을 위한 지질 나노입자 및 이의 사용 방법
|
|
TWI868755B
(zh)
|
2022-06-24 |
2025-01-01 |
丹麥商諾佛 儂迪克股份有限公司 |
抑制跨膜絲胺酸蛋白酶6(tmprss6)表現的組成物及方法
|
|
WO2024028325A1
(en)
|
2022-08-01 |
2024-02-08 |
BioNTech SE |
Nucleic acid compositions comprising amphiphilic oligo ethylene glycol (oeg)-conjugated compounds and methods of using such compounds and compositions
|
|
TW202430637A
(zh)
|
2022-11-16 |
2024-08-01 |
美商戴瑟納製藥股份有限公司 |
Stat3靶向性寡核苷酸及其用途
|
|
KR20250122544A
(ko)
|
2022-11-21 |
2025-08-13 |
이오반스 바이오테라퓨틱스, 인크. |
종양 침윤 림프구의 확장을 위한 2차원 공정 및 이를 통한 요법
|
|
WO2024189064A1
(en)
|
2023-03-14 |
2024-09-19 |
Institut National de la Santé et de la Recherche Médicale |
The circular rna circltbp2 as a biomarker and biotarget in intrahepatic cholangiocarcinomas
|
|
TW202511486A
(zh)
|
2023-07-28 |
2025-03-16 |
美商黛瑟納製藥公司 |
用於程式化死亡配體受體(pd-l1)表現之組成物和方法
|
|
WO2025054459A1
(en)
|
2023-09-08 |
2025-03-13 |
Dicerna Pharmaceuticals, Inc. |
Rnai oligonucleotide conjugates
|
|
WO2025061810A1
(en)
|
2023-09-20 |
2025-03-27 |
Institut National de la Santé et de la Recherche Médicale |
Use of a mirna inhibitor for the treatment of osteogenesis imperfecta
|
|
US20260055414A1
(en)
|
2024-08-21 |
2026-02-26 |
Novo Nordisk A/S |
Compositions and methods for inhibiting xdh expression
|