DE602006020617D1 - Lactoferrin-peptide, geeignet als in die zelle eindringende peptide - Google Patents
Lactoferrin-peptide, geeignet als in die zelle eindringende peptideInfo
- Publication number
- DE602006020617D1 DE602006020617D1 DE602006020617T DE602006020617T DE602006020617D1 DE 602006020617 D1 DE602006020617 D1 DE 602006020617D1 DE 602006020617 T DE602006020617 T DE 602006020617T DE 602006020617 T DE602006020617 T DE 602006020617T DE 602006020617 D1 DE602006020617 D1 DE 602006020617D1
- Authority
- DE
- Germany
- Prior art keywords
- peptide
- peptides
- cell
- lactoferrin
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/644—Transferrin, e.g. a lactoferrin or ovotransferrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05028755 | 2005-12-30 | ||
PCT/EP2006/010271 WO2007076904A1 (en) | 2005-12-30 | 2006-10-25 | Peptides useful as cell-penetrating peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006020617D1 true DE602006020617D1 (de) | 2011-04-21 |
Family
ID=37491778
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006020617T Active DE602006020617D1 (de) | 2005-12-30 | 2006-10-25 | Lactoferrin-peptide, geeignet als in die zelle eindringende peptide |
Country Status (16)
Country | Link |
---|---|
US (3) | US20100061932A1 (de) |
EP (1) | EP1966240B3 (de) |
JP (1) | JP5264502B2 (de) |
KR (1) | KR101317100B1 (de) |
CN (1) | CN101395180B (de) |
AT (1) | ATE501169T1 (de) |
AU (1) | AU2006332193B2 (de) |
BR (1) | BRPI0620806B8 (de) |
CA (1) | CA2646833C (de) |
DE (1) | DE602006020617D1 (de) |
ES (1) | ES2361621T7 (de) |
IL (1) | IL192131A (de) |
MX (1) | MX2008008548A (de) |
PL (1) | PL1966240T6 (de) |
SI (1) | SI1966240T1 (de) |
WO (1) | WO2007076904A1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005051366A1 (de) | 2005-10-25 | 2007-04-26 | Degussa Gmbh | Drug Delivery Systeme |
EP2050461A1 (de) * | 2007-10-19 | 2009-04-22 | PharmaSurgics in Sweden AB | Peptide basierend auf der menschlichen Lactoferrinsequenz und ihre Verwendung |
EP2090584A1 (de) * | 2008-02-13 | 2009-08-19 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Identifikation eines neuartigen Zystein-reichen Peptids zur Zellenpenetration |
JP4711013B2 (ja) * | 2008-02-28 | 2011-06-29 | 東レ株式会社 | 経鼻投与用医薬組成物 |
CA2766634A1 (en) * | 2009-06-22 | 2011-01-13 | Burnham Institute For Medical Research | Methods and compositions using peptides and proteins with c-terminal elements |
JP5818319B2 (ja) * | 2009-12-14 | 2015-11-18 | 国立大学法人北海道大学 | 脂質膜構造体に細胞透過能を付与および/または脂質膜構造体の細胞透過能を増強するペプチド、ならびにそれらペプチドと結合した脂質を構成脂質として含む、細胞透過能を有するまたは細胞透過能が増強された脂質膜構造体 |
WO2011084061A1 (en) | 2010-01-08 | 2011-07-14 | Universitair Medisch Centrum St. Radboud | Cpp (cell penetrating peptide) and its uses |
FR2955773B1 (fr) * | 2010-02-01 | 2017-05-26 | Commissariat A L'energie Atomique | Complexe moleculaire de ciblage des antigenes vers les cellules presentatrices d'antigene et ses applications pour la vaccination |
SI2643344T1 (sl) | 2010-11-26 | 2017-07-31 | Evonik Roehm Gmbh | Peptid pridobljen iz humanega laktoferina za uporabo kot sredstvo za maskiranje antigena |
CN102174078A (zh) * | 2011-01-10 | 2011-09-07 | 中国药科大学 | 肿瘤细胞选择性穿膜肽的应用 |
CN102091036A (zh) * | 2011-01-10 | 2011-06-15 | 中国药科大学 | 一种含有抗肿瘤药物的复合脂质体及其制备方法和用途 |
CN102153629B (zh) * | 2011-01-20 | 2013-07-24 | 华中科技大学 | 一种短肽及其应用 |
WO2012118778A1 (en) | 2011-02-28 | 2012-09-07 | Sanford-Burnham Medical Research Institute | Truncated car peptides and methods and compositions using truncated car peptides |
WO2012166585A2 (en) | 2011-05-31 | 2012-12-06 | Airware, Inc. | Re-calibration of ab ndir gas sensors |
US10179801B2 (en) | 2011-08-26 | 2019-01-15 | Sanford-Burnham Medical Research Institute | Truncated LYP-1 peptides and methods and compositions using truncated LYP-1 peptides |
CN102988295B (zh) * | 2011-09-09 | 2015-07-29 | 复旦大学 | 一种穿膜肽修饰的纳米粒及其制备方法 |
CN102993296A (zh) * | 2011-09-14 | 2013-03-27 | 广州格拉姆生物科技有限公司 | 牛乳铁蛋白肽及其制备方法 |
US8669226B2 (en) | 2011-10-07 | 2014-03-11 | Morehouse School Of Medicine | Antimicrobial compositions and methods of use thereof |
WO2013052058A1 (en) * | 2011-10-07 | 2013-04-11 | Morehouse School Of Medicine | Antimicrobial compositions and methods of use thereof |
DE102011055229A1 (de) | 2011-11-10 | 2013-05-16 | Evonik Degussa Gmbh | Verfahren zur Bereitstellung von Regelleistung mit einem Energiespeicher unter Ausnutzung von Toleranzen bei der Bestimmung der Frequenzabweichung |
DE102011055231A1 (de) * | 2011-11-10 | 2013-05-16 | Evonik Industries Ag | Verfahren zur Bereitstellung von Regelleistung |
CN110251682B (zh) | 2011-11-24 | 2022-12-06 | 苏州宝时得电动工具有限公司 | 多肽序列设计及其在多肽介导的siRNA传递中的应用 |
CN103169982B (zh) * | 2011-12-23 | 2015-05-20 | 中国科学院上海药物研究所 | 生物活性肽修饰的纳米银及其制备方法和用途 |
CN103382217B (zh) * | 2012-12-11 | 2015-05-27 | 任发政 | 穿膜肽和药物组合物及其制备方法和应用 |
CN105491982B (zh) * | 2013-08-12 | 2019-09-10 | 3M创新有限公司 | 用于增强透皮递送的肽 |
WO2015075747A1 (en) * | 2013-11-19 | 2015-05-28 | Council Of Scientific And Industrial Research | Cell-penetrating peptide for biomolecule delivery |
JP6912887B2 (ja) * | 2013-12-12 | 2021-08-04 | ライフ テクノロジーズ コーポレーション | トランスフェクションの強化のための膜透過性ペプチドならびにそれらを使用する組成物及び方法 |
CN103784406A (zh) * | 2014-01-20 | 2014-05-14 | 同济大学 | 一种偶联穿膜肽和mmp酶切位点的纳米颗粒 |
WO2016136707A1 (ja) * | 2015-02-27 | 2016-09-01 | 学校法人常翔学園 | 膜透過性ペプチド鎖を有する多糖誘導体 |
KR101647804B1 (ko) * | 2015-06-24 | 2016-08-11 | 한국과학기술연구원 | 신규 세포투과 펩타이드 및 이의 용도 |
CN108456254B (zh) * | 2017-02-20 | 2021-06-01 | 中国科学院上海药物研究所 | 一种tcs-穿膜肽-肿瘤蛋白酶底物肽融合蛋白、其制备方法和用途 |
EP3628047A1 (de) | 2017-05-02 | 2020-04-01 | Sanford Burnham Prebys Medical Discovery Institute | Tumorassoziiertes monozyten-/makrophagenbindendes peptid und verfahren zur verwendung davon |
CN108101966B (zh) * | 2017-12-26 | 2020-10-27 | 暨南大学 | 基于细胞穿膜肽的氧化还原敏感多肽及其在疫苗载体中的应用 |
US11052053B2 (en) | 2018-05-08 | 2021-07-06 | Evonik Operations Gmbh | Nanoparticle comprising a bio-resorbable polyester, a hydrophilic polymer and an acylated human lactoferrin-derived peptide |
CN111499759B (zh) * | 2019-01-31 | 2022-12-20 | 上海科技大学 | 一种具有细胞穿膜性的锌指蛋白-乳铁蛋白融合蛋白质及其制备与应用 |
AU2020218940A1 (en) | 2019-02-04 | 2021-08-12 | University Of Tartu | Bi-specific extracellular matrix binding peptides and methods of use thereof |
CN110078834B (zh) * | 2019-05-05 | 2021-07-30 | 华中科技大学 | 一种类短肽、辅助透膜剂及其应用 |
CN112426438B (zh) * | 2019-11-14 | 2023-12-05 | 上海鑫湾生物科技有限公司 | 用于调控酸性环境免疫应答的组合物、其制备方法和用途 |
WO2023186757A1 (en) | 2022-03-30 | 2023-10-05 | Evonik Operations Gmbh | Formulations composed of cationic lipids and poly(lactic-co-glycolic acid) for the delivery of polynucleotides into cells |
WO2024079331A1 (en) * | 2022-10-13 | 2024-04-18 | Stichting Radboud Universitair Medisch Centrum | A complex comprising a cargo and a targeting moiety binding intelectin-1 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5633076A (en) * | 1989-12-01 | 1997-05-27 | Pharming Bv | Method of producing a transgenic bovine or transgenic bovine embryo |
EP0533838B1 (de) | 1990-06-11 | 1997-12-03 | NeXstar Pharmaceuticals, Inc. | Nukleinsäureliganden |
JP2818056B2 (ja) | 1990-09-07 | 1998-10-30 | 森永乳業株式会社 | 抗菌性ペプチドおよび抗菌剤 |
JP3207535B2 (ja) * | 1992-08-07 | 2001-09-10 | 森永乳業株式会社 | 抗酸化剤 |
JP3312946B2 (ja) | 1993-03-04 | 2002-08-12 | 雪印乳業株式会社 | ウイルス感染・増殖抑制剤 |
DE59708838D1 (de) | 1996-08-30 | 2003-01-09 | Jens Peter Fuerste | Spiegelselektion und spiegelevolution von nucleinsäuren |
US5849902A (en) | 1996-09-26 | 1998-12-15 | Oligos Etc. Inc. | Three component chimeric antisense oligonucleotides |
US5989912A (en) | 1996-11-21 | 1999-11-23 | Oligos Etc. Inc. | Three component chimeric antisense oligonucleotides |
DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
SE9804614A0 (en) * | 1998-07-06 | 2000-01-07 | A+ Science Invest Ab | New peptides and use thereof |
AU4656999A (en) * | 1998-07-15 | 2000-02-07 | Samyang Genex Corporation | Mass production method of lactoferrin polypeptide from yeast and useful microorganism thereof |
US6423509B1 (en) * | 1998-07-15 | 2002-07-23 | Samyang Genex Corporation | Pichia pastoris strain for producing lactoferrin and methods of use |
GB9818938D0 (en) * | 1998-08-28 | 1998-10-21 | Alpharma As | Bioactive peptides |
DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
US6399570B1 (en) * | 1999-02-05 | 2002-06-04 | Agennix, Inc. | Antimicrobial/endotoxin neutralizing polypeptide |
CA2404890C (en) | 2000-03-30 | 2013-11-19 | Whitehead Institute For Biomedical Research | Rna sequence-specific mediators of rna interference |
RU2197987C2 (ru) * | 2000-07-07 | 2003-02-10 | Закрытое акционерное общество "АСГЛ-Исследовательские Лаборатории" | Носитель чужеродной генетической информации для генной терапии |
-
2006
- 2006-10-25 CN CN200680049953.0A patent/CN101395180B/zh active Active
- 2006-10-25 AT AT06806526T patent/ATE501169T1/de active
- 2006-10-25 EP EP06806526A patent/EP1966240B3/de active Active
- 2006-10-25 ES ES06806526T patent/ES2361621T7/es active Active
- 2006-10-25 PL PL06806526T patent/PL1966240T6/pl unknown
- 2006-10-25 SI SI200631008T patent/SI1966240T1/sl unknown
- 2006-10-25 CA CA2646833A patent/CA2646833C/en active Active
- 2006-10-25 KR KR1020087015786A patent/KR101317100B1/ko active IP Right Grant
- 2006-10-25 WO PCT/EP2006/010271 patent/WO2007076904A1/en active Application Filing
- 2006-10-25 AU AU2006332193A patent/AU2006332193B2/en active Active
- 2006-10-25 MX MX2008008548A patent/MX2008008548A/es active IP Right Grant
- 2006-10-25 US US12/159,226 patent/US20100061932A1/en not_active Abandoned
- 2006-10-25 JP JP2008547861A patent/JP5264502B2/ja active Active
- 2006-10-25 BR BRPI0620806A patent/BRPI0620806B8/pt active IP Right Grant
- 2006-10-25 DE DE602006020617T patent/DE602006020617D1/de active Active
-
2008
- 2008-06-12 IL IL192131A patent/IL192131A/en active IP Right Grant
-
2012
- 2012-07-25 US US13/557,706 patent/US9403884B2/en active Active
-
2015
- 2015-12-01 US US14/955,696 patent/US20160151504A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2006332193A1 (en) | 2007-07-12 |
BRPI0620806A2 (pt) | 2011-11-22 |
CN101395180A (zh) | 2009-03-25 |
KR20080091120A (ko) | 2008-10-09 |
EP1966240A1 (de) | 2008-09-10 |
EP1966240B1 (de) | 2011-03-09 |
CA2646833C (en) | 2019-07-30 |
ES2361621T3 (es) | 2011-06-20 |
ES2361621T7 (es) | 2012-06-14 |
AU2006332193B2 (en) | 2012-06-28 |
CA2646833A1 (en) | 2007-07-12 |
EP1966240B3 (de) | 2011-12-28 |
US9403884B2 (en) | 2016-08-02 |
JP5264502B2 (ja) | 2013-08-14 |
KR101317100B1 (ko) | 2013-10-15 |
BRPI0620806B1 (pt) | 2017-12-05 |
US20100061932A1 (en) | 2010-03-11 |
PL1966240T3 (pl) | 2011-08-31 |
JP2009521908A (ja) | 2009-06-11 |
BRPI0620806B8 (pt) | 2022-07-05 |
ATE501169T1 (de) | 2011-03-15 |
US20160151504A1 (en) | 2016-06-02 |
IL192131A (en) | 2011-10-31 |
CN101395180B (zh) | 2016-06-22 |
MX2008008548A (es) | 2008-09-10 |
PL1966240T6 (pl) | 2012-05-31 |
WO2007076904A1 (en) | 2007-07-12 |
SI1966240T1 (sl) | 2011-06-30 |
IL192131A0 (en) | 2008-12-29 |
US20130108662A1 (en) | 2013-05-02 |
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