MX339050B - Composiciones organicas para tratar las enfermedades relacionadas con hsf1. - Google Patents

Composiciones organicas para tratar las enfermedades relacionadas con hsf1.

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Publication number
MX339050B
MX339050B MX2012007032A MX2012007032A MX339050B MX 339050 B MX339050 B MX 339050B MX 2012007032 A MX2012007032 A MX 2012007032A MX 2012007032 A MX2012007032 A MX 2012007032A MX 339050 B MX339050 B MX 339050B
Authority
MX
Mexico
Prior art keywords
related diseases
organic compositions
hsf1
treat
treat hsf1
Prior art date
Application number
MX2012007032A
Other languages
English (en)
Other versions
MX2012007032A (es
Inventor
Markus Warmuth
Gregory Hinkle
Satyanarayana Kuchimanchi
Stuard Milstein
Wenlai Zhou
Ping Zhu
Tracy S Zimmermann
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2012007032A publication Critical patent/MX2012007032A/es
Publication of MX339050B publication Critical patent/MX339050B/es

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P31/12—Antivirals
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
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    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N2310/00—Structure or type of the nucleic acid
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Abstract

La presente invención se refiere a métodos para el tratamiento de enfermedades relacionadas con el factor de choque por calor 1 (HSF1), tales como cáncer y enfermedades virales, utilizando una cantidad terapéuticamente efectiva de un agente de ARNi para HSF.
MX2012007032A 2009-12-18 2010-12-16 Composiciones organicas para tratar las enfermedades relacionadas con hsf1. MX339050B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28813709P 2009-12-18 2009-12-18
PCT/EP2010/069917 WO2011073326A2 (en) 2009-12-18 2010-12-16 Organic compositions to treat hsf1-related diseases

Publications (2)

Publication Number Publication Date
MX2012007032A MX2012007032A (es) 2012-07-04
MX339050B true MX339050B (es) 2016-05-09

Family

ID=43646461

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2015013656A MX348526B (es) 2009-12-18 2010-12-16 Composiciones orgánicas para tratar las enfermedades relacionadas con hsf1.
MX2017007968A MX369004B (es) 2009-12-18 2010-12-16 Composiciones orgánicas para tratar las enfermedades relacionadas con hsf1.
MX2012007032A MX339050B (es) 2009-12-18 2010-12-16 Composiciones organicas para tratar las enfermedades relacionadas con hsf1.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2015013656A MX348526B (es) 2009-12-18 2010-12-16 Composiciones orgánicas para tratar las enfermedades relacionadas con hsf1.
MX2017007968A MX369004B (es) 2009-12-18 2010-12-16 Composiciones orgánicas para tratar las enfermedades relacionadas con hsf1.

Country Status (14)

Country Link
US (8) US8293718B2 (es)
EP (4) EP3000885B1 (es)
JP (2) JP5819848B2 (es)
KR (2) KR101605932B1 (es)
CN (2) CN102686729B (es)
AR (1) AR079494A1 (es)
AU (1) AU2010332881B2 (es)
BR (1) BR112012014760A2 (es)
CA (2) CA3112716A1 (es)
HK (1) HK1214949A1 (es)
MX (3) MX348526B (es)
TW (1) TWI576108B (es)
UY (1) UY33114A (es)
WO (1) WO2011073326A2 (es)

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