|
JP4341949B2
(ja)
|
2000-09-01 |
2009-10-14 |
ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド |
アザ複素環式誘導体およびその治療的使用
|
|
BRPI0113757B8
(pt)
|
2000-09-11 |
2017-11-07 |
Chiron Corp |
derivados de quinolinona como inibidores de tirosina quinase
|
|
US20030028018A1
(en)
*
|
2000-09-11 |
2003-02-06 |
Chiron Coporation |
Quinolinone derivatives
|
|
JP2004536113A
(ja)
*
|
2001-07-03 |
2004-12-02 |
カイロン コーポレイション |
チロシンキナーゼおよびセリン/スレオニンキナーゼのインヒビターとしてのインダゾールベンズイミダゾール化合物
|
|
US7642278B2
(en)
*
|
2001-07-03 |
2010-01-05 |
Novartis Vaccines And Diagnostics, Inc. |
Indazole benzimidazole compounds
|
|
WO2003045929A1
(en)
|
2001-11-26 |
2003-06-05 |
Takeda Chemical Industries, Ltd. |
Bicyclic derivative, process for producing the same, and use
|
|
US6822097B1
(en)
*
|
2002-02-07 |
2004-11-23 |
Amgen, Inc. |
Compounds and methods of uses
|
|
WO2003106452A2
(en)
*
|
2002-06-12 |
2003-12-24 |
Millennium Pharmaceuticals, Inc. |
Antagonists of melanin concentrating hormone receptor
|
|
DE10238002A1
(de)
|
2002-08-20 |
2004-03-04 |
Merck Patent Gmbh |
Benzimidazolderivate
|
|
US7825132B2
(en)
|
2002-08-23 |
2010-11-02 |
Novartis Vaccines And Diagnostics, Inc. |
Inhibition of FGFR3 and treatment of multiple myeloma
|
|
EP2573079A3
(en)
*
|
2002-08-23 |
2015-03-11 |
Novartis AG |
Benzimidazole quinolinones and uses thereof
|
|
CN100526312C
(zh)
*
|
2002-08-23 |
2009-08-12 |
诺华疫苗和诊断公司 |
苯并咪唑喹啉酮及其应用
|
|
US20050256157A1
(en)
*
|
2002-08-23 |
2005-11-17 |
Chiron Corporation |
Combination therapy with CHK1 inhibitors
|
|
EP1545529A4
(en)
*
|
2002-09-30 |
2010-03-03 |
Bristol Myers Squibb Co |
NEW TYROSINE KINASE HEMMER
|
|
CN100377709C
(zh)
*
|
2002-11-13 |
2008-04-02 |
希龙公司 |
受体酪氨酸激酶抑制剂的制药用途及相关检测方法
|
|
SG148864A1
(en)
*
|
2002-11-13 |
2009-01-29 |
Chiron Corp |
Methods of treating cancer and related methods
|
|
WO2004069160A2
(en)
*
|
2003-01-28 |
2004-08-19 |
Smithkline Beecham Corporation |
Chemical compounds
|
|
WO2004087153A2
(en)
*
|
2003-03-28 |
2004-10-14 |
Chiron Corporation |
Use of organic compounds for immunopotentiation
|
|
US7627675B2
(en)
*
|
2003-05-01 |
2009-12-01 |
Cisco Technology, Inc. |
Methods and devices for regulating traffic on a network
|
|
CA2533626A1
(en)
|
2003-07-22 |
2005-02-03 |
Janssen Pharmaceutica, N.V. |
Quinolinone derivatives as inhibitors of c-fms kinase
|
|
US7872014B2
(en)
|
2003-07-23 |
2011-01-18 |
Exelixis, Inc. |
Anaplastic lymphoma kinase modulators and methods of use
|
|
CN1976706B
(zh)
*
|
2003-11-07 |
2012-01-18 |
诺华疫苗和诊断公司 |
抑制fgfr3及治疗多发性骨髓瘤
|
|
JP4823914B2
(ja)
*
|
2003-11-07 |
2011-11-24 |
ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド |
Fgfr3の阻害および多発性骨髄腫の治療
|
|
WO2005048953A2
(en)
*
|
2003-11-13 |
2005-06-02 |
Ambit Biosciences Corporation |
Amide derivatives as kinase modulators
|
|
WO2005053692A1
(en)
*
|
2003-12-01 |
2005-06-16 |
The Scripps Research Institute |
Advanced quinolinone based protein kinase inhibitors
|
|
EP1718306A2
(en)
*
|
2004-02-20 |
2006-11-08 |
Chiron Corporation |
Modulation of inflammatory and metastatic processes
|
|
GB0420722D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
US7759342B2
(en)
|
2005-01-13 |
2010-07-20 |
Signal Pharmaceuticals, Llc |
Methods of treatment and prevention using haloaryl substituted aminopurines
|
|
US7723340B2
(en)
|
2005-01-13 |
2010-05-25 |
Signal Pharmaceuticals, Llc |
Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
|
|
US7521446B2
(en)
|
2005-01-13 |
2009-04-21 |
Signal Pharmaceuticals, Llc |
Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
|
|
DK1845990T3
(da)
*
|
2005-01-27 |
2012-01-02 |
Novartis Vaccines & Diagnostic |
Behandling af metastaserede tumorer
|
|
US7534796B2
(en)
|
2005-02-18 |
2009-05-19 |
Wyeth |
Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor
|
|
US7582634B2
(en)
|
2005-02-18 |
2009-09-01 |
Wyeth |
7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
|
|
AU2006214064B2
(en)
|
2005-02-18 |
2012-04-26 |
J. Craig Venter Institute, Inc. |
Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli
|
|
JP2008530245A
(ja)
|
2005-02-18 |
2008-08-07 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド |
尿路病原性菌株由来の抗原
|
|
US7538113B2
(en)
|
2005-02-18 |
2009-05-26 |
Wyeth |
4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
|
|
AU2006247803B2
(en)
*
|
2005-05-13 |
2011-12-22 |
Novartis Ag |
Methods for treating drug resistant cancer
|
|
CA2608087C
(en)
|
2005-05-17 |
2013-12-10 |
Gabriel Calvin |
Methods for synthesizing heterocyclic compounds
|
|
US7531542B2
(en)
|
2005-05-18 |
2009-05-12 |
Wyeth |
Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor
|
|
EP2270000B1
(en)
|
2005-05-23 |
2015-07-29 |
Novartis AG |
Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one lactic acid salts
|
|
US7582636B2
(en)
|
2005-05-26 |
2009-09-01 |
Wyeth |
Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor
|
|
EP2614709A1
(en)
|
2005-07-18 |
2013-07-17 |
Novartis AG |
Small animal model for HCV replication
|
|
BRPI0617252A2
(pt)
*
|
2005-10-14 |
2011-07-19 |
Hoffmann La Roche |
regime de administração para benzodiazepina 5-2-clorofenil)-1,2-diidro-7-flìor-8-metóxi-3-metil-pira zolo [3,4-b] [1,4]
|
|
WO2007052055A1
(en)
|
2005-11-04 |
2007-05-10 |
Novartis Vaccines And Diagnostics Srl |
Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture
|
|
CA2628424A1
(en)
|
2005-11-04 |
2007-05-10 |
Novartis Vaccines And Diagnostics S.R.L. |
Adjuvanted influenza vaccines including cytokine-inducing agents
|
|
ES2377884T3
(es)
|
2005-11-04 |
2012-04-02 |
Novartis Vaccines And Diagnostics S.R.L. |
Vacunas contra la gripe que incluyen combinaciones de adyuvantes particulados e inmunopotenciadores
|
|
NZ594482A
(en)
|
2005-11-04 |
2012-11-30 |
Novartis Vaccines & Diagnostic |
Influenza vaccines with reduced amount of oil-in-water emulsion as adjuvant
|
|
DE102005054904A1
(de)
*
|
2005-11-17 |
2007-05-24 |
Wacker Polymer Systems Gmbh & Co. Kg |
Verfahren zur Herstellung polyvinylalkoholstabilisierter Latices
|
|
KR20080074143A
(ko)
|
2005-11-29 |
2008-08-12 |
노파르티스 아게 |
퀴놀리논 제제
|
|
WO2007067968A2
(en)
|
2005-12-08 |
2007-06-14 |
Novartis Ag |
Effects of inhibitors of fgfr3 on gene transcription
|
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
|
PL2478916T3
(pl)
|
2006-01-27 |
2020-11-16 |
Seqirus UK Limited |
Szczepionki przeciw grypie zawierające hemaglutyninę i białka macierzy
|
|
PE20070978A1
(es)
*
|
2006-02-14 |
2007-11-15 |
Novartis Ag |
COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE FOSFATIDILINOSITOL 3-QUINASAS (PI3Ks)
|
|
TW200803855A
(en)
*
|
2006-02-24 |
2008-01-16 |
Kalypsys Inc |
Quinolones useful as inducible nitric oxide synthase inhibitors
|
|
AR059898A1
(es)
|
2006-03-15 |
2008-05-07 |
Janssen Pharmaceutica Nv |
Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
|
|
EP2010530A2
(en)
*
|
2006-03-23 |
2009-01-07 |
Novartis AG |
Methods for the preparation of imidazole-containing compounds
|
|
CA2646891A1
(en)
*
|
2006-03-23 |
2007-09-27 |
Novartis Ag |
Immunopotentiating compounds
|
|
ATE539079T1
(de)
|
2006-03-23 |
2012-01-15 |
Novartis Ag |
Imidazochinoxalinverbindungen als immunmodulatoren
|
|
WO2007110776A1
(en)
|
2006-03-24 |
2007-10-04 |
Novartis Vaccines And Diagnostics Gmbh & Co Kg |
Storage of influenza vaccines without refrigeration
|
|
EP2019686B1
(en)
|
2006-03-31 |
2012-07-11 |
Novartis AG |
Combined mucosal and parenteral immunization against hiv
|
|
TW200808739A
(en)
*
|
2006-04-06 |
2008-02-16 |
Novartis Vaccines & Diagnostic |
Quinazolines for PDK1 inhibition
|
|
MX2008013430A
(es)
|
2006-04-19 |
2009-01-26 |
Novartis Vaccines & Diagnostic |
Compuestos de indazol y metodos para la inhibición de cdc7.
|
|
DK2054431T3
(da)
|
2006-06-09 |
2012-01-02 |
Novartis Ag |
Konformere af bakterielle adhæsiner
|
|
US8080563B2
(en)
|
2006-07-07 |
2011-12-20 |
Kalypsys |
Bicyclic heteroaryl inhibitors of PDE4
|
|
US8138205B2
(en)
|
2006-07-07 |
2012-03-20 |
Kalypsys, Inc. |
Heteroarylalkoxy-substituted quinolone inhibitors of PDE4
|
|
GB0614460D0
(en)
|
2006-07-20 |
2006-08-30 |
Novartis Ag |
Vaccines
|
|
EP2586790A3
(en)
|
2006-08-16 |
2013-08-14 |
Novartis AG |
Immunogens from uropathogenic Escherichia coli
|
|
NZ575271A
(en)
|
2006-09-11 |
2011-09-30 |
Novartis Ag |
Making influenza virus vaccines without using eggs
|
|
US8883790B2
(en)
|
2006-10-12 |
2014-11-11 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
|
US8916552B2
(en)
|
2006-10-12 |
2014-12-23 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
|
JP2011506264A
(ja)
|
2006-12-06 |
2011-03-03 |
ノバルティス アーゲー |
インフルエンザウイルスの4つの株に由来する抗原を含むワクチン
|
|
GB0700562D0
(en)
|
2007-01-11 |
2007-02-21 |
Novartis Vaccines & Diagnostic |
Modified Saccharides
|
|
TW200900065A
(en)
|
2007-03-07 |
2009-01-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
|
|
TW200845978A
(en)
|
2007-03-07 |
2008-12-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
|
|
UA101611C2
(ru)
*
|
2007-04-03 |
2013-04-25 |
Аррей Байофарма Инк. |
СОЕДИНЕНИЯ ИМИДАЗО[1,2-а]ПИРИДИНА КАК ИНГИБИТОРЫ ТИРОЗИНКИНАЗЫ РЕЦЕПТОРОВ
|
|
EP2481735A1
(en)
*
|
2007-05-09 |
2012-08-01 |
Pfizer Inc. |
Substituted heterocyclic derivatives and compositions and their pharmaceutical use as antibacterials
|
|
PT2185191E
(pt)
|
2007-06-27 |
2012-11-27 |
Novartis Ag |
Vacinas contra a gripe com baixo teor de aditivos
|
|
GB0713880D0
(en)
*
|
2007-07-17 |
2007-08-29 |
Novartis Ag |
Conjugate purification
|
|
GB0714963D0
(en)
|
2007-08-01 |
2007-09-12 |
Novartis Ag |
Compositions comprising antigens
|
|
TW200922566A
(en)
|
2007-09-14 |
2009-06-01 |
Ortho Mcneil Janssen Pharm |
1,3 disubstituted 4-(aryl-X-phenyl)-1H-pyridin-2-ones
|
|
EA017648B1
(ru)
|
2007-09-14 |
2013-02-28 |
Орто-Макнейл-Янссен Фармасьютикалз, Инк. |
1',3'-двузамещенные-4-фенил-3,4,5,6-тетрагидро-2н,1'н-[1,4']бипириди-нил-2'-оны
|
|
GB0810305D0
(en)
|
2008-06-05 |
2008-07-09 |
Novartis Ag |
Influenza vaccination
|
|
JP2011506560A
(ja)
|
2007-12-20 |
2011-03-03 |
ノバルティス アーゲー |
Pi3キナーゼ阻害剤として用いられるチアゾール誘導体
|
|
GB0818453D0
(en)
|
2008-10-08 |
2008-11-12 |
Novartis Ag |
Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
|
|
JP5518041B2
(ja)
|
2008-03-18 |
2014-06-11 |
ノバルティス アーゲー |
インフルエンザウイルスワクチン抗原の調製における改良
|
|
AR070924A1
(es)
*
|
2008-03-19 |
2010-05-12 |
Novartis Ag |
Formas cristalinas y dos formas solvatadas de sales del acido lactico de 4- amino -5- fluoro-3-(5-(4-metilpiperazin-1-il ) -1h- bencimidazol-2-il) quinolin -2-(1h) - ona
|
|
JP5547194B2
(ja)
|
2008-09-02 |
2014-07-09 |
ジャンセン ファーマシューティカルズ, インコーポレイテッド. |
代謝型グルタミン酸受容体の調節因子としての3−アザビシクロ[3.1.0]ヘキシル誘導体
|
|
JP5690277B2
(ja)
|
2008-11-28 |
2015-03-25 |
ジャンセン ファーマシューティカルズ, インコーポレイテッド. |
代謝型グルタミン酸受容体の調節因子としてのインドールおよびベンゾオキサジン誘導体
|
|
WO2010100632A2
(en)
|
2009-03-06 |
2010-09-10 |
Novartis Ag |
Chlamydia antigens
|
|
EP2419129A2
(en)
|
2009-04-14 |
2012-02-22 |
Novartis AG |
Compositions for immunising against staphylococcus aerus
|
|
DE102010018462A1
(de)
|
2009-04-27 |
2011-04-07 |
Novartis Ag |
Impfstoffe zum Schutz gegen Influenza
|
|
TWI410418B
(zh)
|
2009-04-29 |
2013-10-01 |
Ind Tech Res Inst |
氮雜薁化合物、藥學組合物與抑制一細胞中蛋白質激酶之活性的方法
|
|
JO2860B1
(en)
|
2009-05-07 |
2015-03-15 |
ايلي ليلي اند كومباني |
Phenylendazolyl compounds
|
|
CN102439015B
(zh)
|
2009-05-12 |
2015-05-13 |
杨森制药有限公司 |
1,2,4-三唑并[4,3-a]吡啶衍生物和其作为mGluR2受体的正向变构调节剂的用途
|
|
MY153913A
(en)
|
2009-05-12 |
2015-04-15 |
Janssen Pharmaceuticals Inc |
7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
|
HRP20131122T1
(hr)
|
2009-05-12 |
2013-12-20 |
Janssen Pharmaceuticals, Inc. |
Derivati 1,2,4-triazolo[4,3-a] piridina i njihova uporaba u lijeäśenju ili prevenciji neuroloških i psihijatrijskih poremeä†aja
|
|
US8293753B2
(en)
|
2009-07-02 |
2012-10-23 |
Novartis Ag |
Substituted 2-carboxamide cycloamino ureas
|
|
US10988511B2
(en)
|
2009-07-07 |
2021-04-27 |
Glaxosmithkline Biologicals Sa |
Conserved Escherichia bacterial IG-like domain (group 1) protein (ORF405) immunogens
|
|
EP4183412B1
(en)
|
2009-07-15 |
2024-08-14 |
GlaxoSmithKline Biologicals SA |
Rsv f protein compositions and methods for making same
|
|
CA2768343A1
(en)
|
2009-07-16 |
2011-01-20 |
Novartis Ag |
Detoxified escherichia coli immunogens
|
|
JPWO2011033588A1
(ja)
*
|
2009-09-18 |
2013-02-07 |
株式会社アドバンテスト |
試験装置および試験方法
|
|
GB0918392D0
(en)
|
2009-10-20 |
2009-12-02 |
Novartis Ag |
Diagnostic and therapeutic methods
|
|
GB0919690D0
(en)
|
2009-11-10 |
2009-12-23 |
Guy S And St Thomas S Nhs Foun |
compositions for immunising against staphylococcus aureus
|
|
US20120258940A1
(en)
|
2009-12-18 |
2012-10-11 |
Giordano Caponigro |
Method for treating haematological cancers
|
|
EP2519265B1
(en)
|
2009-12-30 |
2018-11-14 |
GlaxoSmithKline Biologicals SA |
Polysaccharide immunogens conjugated to e. coli carrier proteins
|
|
US8741903B2
(en)
|
2010-04-16 |
2014-06-03 |
Novartis Ag |
Organic compound for use in the treatment of hepatocellular cancer (HCC)
|
|
WO2011128405A1
(en)
|
2010-04-16 |
2011-10-20 |
Novartis Ag |
Combination of organic compounds
|
|
CN102933267B
(zh)
|
2010-05-28 |
2015-05-27 |
泰特里斯在线公司 |
交互式混合异步计算机游戏基础结构
|
|
GB201009861D0
(en)
|
2010-06-11 |
2010-07-21 |
Novartis Ag |
OMV vaccines
|
|
AR081776A1
(es)
|
2010-06-30 |
2012-10-17 |
Novartis Ag |
Composiciones farmaceuticas que comprenden monohidrato de lactato de 4-amino-5-fluoro-3-[6-(4-metil-piperazin-1-il)-1h-bencimidazol-2-il]-1h-quinolin-2-ona, proceso para la produccion de la composicion
|
|
US9192661B2
(en)
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
|
AR082418A1
(es)
|
2010-08-02 |
2012-12-05 |
Novartis Ag |
Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
|
|
JP6039559B2
(ja)
|
2010-09-02 |
2016-12-07 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
Lpa受容体アンタゴニストとしてのピラゾロピリジノン誘導体
|
|
JO3062B1
(ar)
|
2010-10-05 |
2017-03-15 |
Lilly Co Eli |
R)-(e)-2-(4-(2-(5-(1-(3، 5-داي كلورو بيريدين-4-يل)إيثوكسي)-1h-إندازول-3-يل)?ينيل)-1h-بيرازول-1-يل)إيثانول بلوري
|
|
EP2661435B1
(en)
|
2010-11-08 |
2015-08-19 |
Janssen Pharmaceuticals, Inc. |
1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
|
|
ES2536433T3
(es)
|
2010-11-08 |
2015-05-25 |
Janssen Pharmaceuticals, Inc. |
Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2
|
|
JP5852664B2
(ja)
|
2010-11-08 |
2016-02-03 |
ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド |
1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
|
|
ES3018416T3
(es)
|
2011-01-26 |
2025-05-16 |
Glaxosmithkline Biologicals Sa |
Régimen de inmunización del VRS
|
|
WO2012104776A1
(en)
|
2011-01-31 |
2012-08-09 |
Novartis Ag |
Novel heterocyclic derivatives
|
|
US20130345234A1
(en)
|
2011-03-17 |
2013-12-26 |
Humphrey Athelstan Roy Gardner |
Fgfr and ligands thereof as biomarkers for breast cancer in hr positive subjects
|
|
RS56748B1
(sr)
|
2011-05-13 |
2018-03-30 |
Glaxosmithkline Biologicals Sa |
Pre-fuzioni rsv f antigeni
|
|
US20150182525A1
(en)
|
2011-05-19 |
2015-07-02 |
Novartis Ag |
4-Amino-5-Fluoro-3-[6-(4-Methylpiperazin-1-YL)-1H-Benzimidazol-2-YL]-1H-Quinolin-2-one for use in the Treatment of Adenoid Cystic Carcinoma
|
|
EP2554662A1
(en)
|
2011-08-05 |
2013-02-06 |
M Maria Pia Cosma |
Methods of treatment of retinal degeneration diseases
|
|
JP2014526506A
(ja)
|
2011-09-15 |
2014-10-06 |
ノバルティス アーゲー |
中等度肝障害患者の癌治療における4−アミノ−5−フルオロ−3−[6−(4−メチルピペラジン−1−イル)−1h−ベンゾイミダゾール−2−イル]−1h−キノリン−2−オンの使用
|
|
WO2013063003A1
(en)
|
2011-10-28 |
2013-05-02 |
Novartis Ag |
Method of treating gastrointestinal stromal tumors
|
|
SG11201401716XA
(en)
|
2011-10-28 |
2014-05-29 |
Novartis Ag |
Novel purine derivatives and their use in the treatment of disease
|
|
RU2636350C2
(ru)
|
2011-11-07 |
2017-11-22 |
Новартис Аг |
МОЛЕКУЛА, СОДЕРЖАЩАЯ SPR0096 и SPR2021
|
|
MX2014009303A
(es)
|
2012-01-31 |
2014-10-14 |
Novartis Ag |
Combinacion de un inhibidor de rtk con un anti-estrogeno y uso del mismo para el tratamiento de cancer.
|
|
CN104349779A
(zh)
|
2012-05-16 |
2015-02-11 |
诺华股份有限公司 |
Pi-3激酶抑制剂的剂量方案
|
|
AU2013289175A1
(en)
|
2012-07-11 |
2015-01-22 |
Novartis Ag |
Method of treating gastrointestinal stromal tumors
|
|
MX2015004171A
(es)
|
2012-10-02 |
2015-10-22 |
Glaxosmithkline Biolog Sa |
Conjugados de sacaridos no lineales.
|
|
WO2014058785A1
(en)
|
2012-10-10 |
2014-04-17 |
Novartis Ag |
Combination therapy
|
|
CN103804353A
(zh)
*
|
2012-11-01 |
2014-05-21 |
常辉 |
一类治疗精神分裂症的化合物及其用途
|
|
CN105142666A
(zh)
|
2012-11-30 |
2015-12-09 |
葛兰素史密丝克莱恩生物有限公司 |
假单胞菌抗原和抗原组合
|
|
EP2764866A1
(en)
|
2013-02-07 |
2014-08-13 |
IP Gesellschaft für Management mbH |
Inhibitors of nedd8-activating enzyme
|
|
US9353122B2
(en)
|
2013-02-15 |
2016-05-31 |
Kala Pharmaceuticals, Inc. |
Therapeutic compounds and uses thereof
|
|
US9688688B2
(en)
|
2013-02-20 |
2017-06-27 |
Kala Pharmaceuticals, Inc. |
Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
|
|
US9353123B2
(en)
|
2013-02-20 |
2016-05-31 |
Kala Pharmaceuticals, Inc. |
Therapeutic compounds and uses thereof
|
|
WO2014191938A1
(en)
|
2013-05-31 |
2014-12-04 |
Novartis Ag |
Combination therapy containing a pi3k-alpha inhibitor and fgfr kinase inhibitor for treating cancer
|
|
JO3368B1
(ar)
|
2013-06-04 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
|
|
JO3367B1
(ar)
|
2013-09-06 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
|
|
ES2670550T3
(es)
|
2013-10-14 |
2018-05-30 |
Eisai R&D Management Co., Ltd. |
Derivados de quinolina selectivamente sustituidos
|
|
KR101823488B1
(ko)
|
2013-10-14 |
2018-01-30 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
선택적으로 치환된 퀴놀린 화합물
|
|
KR20160099084A
(ko)
|
2013-11-01 |
2016-08-19 |
칼라 파마슈티컬스, 인크. |
치료 화합물의 결정질 형태 및 그의 용도
|
|
US9890173B2
(en)
|
2013-11-01 |
2018-02-13 |
Kala Pharmaceuticals, Inc. |
Crystalline forms of therapeutic compounds and uses thereof
|
|
EP2870974A1
(en)
|
2013-11-08 |
2015-05-13 |
Novartis AG |
Salmonella conjugate vaccines
|
|
DK3076969T3
(da)
|
2013-12-06 |
2021-11-22 |
Novartis Ag |
Doseringsregime for en alfa-isoform-selektiv phosphatidylinositol-3-kinase-hæmmer
|
|
PL3096790T3
(pl)
|
2014-01-21 |
2020-01-31 |
Janssen Pharmaceutica, N.V. |
Kombinacje zawierające pozytywne modulatory allosteryczne lub agonistów ortosterycznych metabotropowego receptora glutaminergicznego podtypu 2 i ich zastosowanie
|
|
ME03518B
(me)
|
2014-01-21 |
2020-04-20 |
Janssen Pharmaceutica Nv |
Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena
|
|
WO2015155738A2
(en)
|
2014-04-09 |
2015-10-15 |
Christopher Rudd |
Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity
|
|
US11179394B2
(en)
|
2014-06-17 |
2021-11-23 |
Vertex Pharmaceuticals Incorporated |
Method for treating cancer using a combination of Chk1 and ATR inhibitors
|
|
WO2016005752A1
(en)
|
2014-07-09 |
2016-01-14 |
Tc Biopharm Ltd |
Gamma delta t cells and uses thereof
|
|
GB201506423D0
(en)
|
2015-04-15 |
2015-05-27 |
Tc Biopharm Ltd |
Gamma delta T cells and uses thereof
|
|
KR101693781B1
(ko)
*
|
2014-10-06 |
2017-01-09 |
한양대학교 에리카산학협력단 |
다이플루오로알킬기가 도입된 방향족 화합물의 제조 방법
|
|
WO2016055916A1
(en)
|
2014-10-06 |
2016-04-14 |
Novartis Ag |
Therapeutic combination for the treatment of cancer
|
|
CN104725431B
(zh)
*
|
2015-03-19 |
2017-05-17 |
广西师范大学 |
喹啉酮衍生物的钴(ⅱ)配合物及其合成方法及应用
|
|
CN104817535A
(zh)
*
|
2015-03-19 |
2015-08-05 |
广西师范大学 |
一种喹啉酮衍生物及其合成方法及应用
|
|
CN104774221B
(zh)
*
|
2015-03-19 |
2017-02-08 |
广西师范大学 |
喹啉酮衍生物的金属配合物及其合成方法及应用
|
|
GB201507368D0
(en)
|
2015-04-30 |
2015-06-17 |
Ucl Business Plc |
Cell
|
|
EP3333157B1
(en)
|
2015-08-07 |
2020-12-23 |
Harbin Zhenbao Pharmaceutical Co., Ltd. |
Vinyl compounds as fgfr and vegfr inhibitors
|
|
AR105911A1
(es)
|
2015-09-03 |
2017-11-22 |
Forma Therapeutics Inc |
Inhibidores de hdac8 bicíclicos fusionados [6,6]
|
|
US11464774B2
(en)
|
2015-09-30 |
2022-10-11 |
Vertex Pharmaceuticals Incorporated |
Method for treating cancer using a combination of DNA damaging agents and ATR inhibitors
|
|
CN108472289A
(zh)
|
2015-11-02 |
2018-08-31 |
诺华股份有限公司 |
磷脂酰肌醇3-激酶抑制剂的给药方案
|
|
EP3231434A1
(en)
|
2016-04-14 |
2017-10-18 |
Fundacio Centre de Regulacio Genomica |
Method of treatment of parkinsonism
|
|
WO2018048750A1
(en)
|
2016-09-08 |
2018-03-15 |
Kala Pharmaceuticals, Inc. |
Crystalline forms of therapeutic compounds and uses thereof
|
|
EP3509421A4
(en)
|
2016-09-08 |
2020-05-20 |
Kala Pharmaceuticals, Inc. |
CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF
|
|
US10253036B2
(en)
|
2016-09-08 |
2019-04-09 |
Kala Pharmaceuticals, Inc. |
Crystalline forms of therapeutic compounds and uses thereof
|
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
Novartis Ag |
Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
|
|
CN107935858B
(zh)
*
|
2016-10-12 |
2020-09-08 |
利尔化学股份有限公司 |
5-氟-2-硝基苯酚的制备方法
|
|
EP3645526B1
(en)
|
2017-06-27 |
2024-09-04 |
Janssen Pharmaceutica NV |
New quinolinone compounds
|
|
BR112020010012A2
(pt)
|
2017-11-24 |
2020-10-13 |
Janssen Pharmaceutica Nv |
compostos de pirazolopiridinona
|
|
AU2018370904B2
(en)
|
2017-11-24 |
2023-09-21 |
Janssen Pharmaceutica Nv |
Pyrazolopyridinone compounds
|
|
US11078194B2
(en)
|
2017-12-07 |
2021-08-03 |
Harbin Zhenbao Pharmaceutical Co., Ltd. |
Salt form and crystal form serving as FGFR and VEGFR inhibitor compounds, and preparation method therefor
|
|
CN109553534A
(zh)
*
|
2018-11-27 |
2019-04-02 |
常州大学 |
一种2-硝基-4-甲氧基苯甲酸的制备方法
|
|
US12398155B2
(en)
|
2018-12-26 |
2025-08-26 |
Janssen Pharmaceutica Nv |
Thienopyridinone compounds
|
|
US10835531B1
(en)
|
2019-06-18 |
2020-11-17 |
Oncology Venture ApS |
Methods for predicting drug responsiveness in cancer patients
|
|
GB201909191D0
(en)
*
|
2019-06-26 |
2019-08-07 |
Ucb Biopharma Sprl |
Therapeutic agents
|
|
AU2021244786A1
(en)
|
2020-03-25 |
2022-11-03 |
Risen (Suzhou) Pharma Tech Co., Ltd. |
Stable heavy isotopes in amide functional groups and uses thereof
|
|
US20250129067A1
(en)
|
2021-11-08 |
2025-04-24 |
Progentos Therapeutics, Inc. |
Platelet-derived growth factor receptor (pdgfr) alpha inhibitors and uses thereof
|
|
WO2025085233A1
(en)
*
|
2023-10-20 |
2025-04-24 |
Ensem Therapeutics, Inc. |
Novel derivatives of quinolinones, and compositions and methods thereof
|