HK1125540A1 - Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro- 4-oxoquinoline-3-carboxamide n-[24-(11-)-5-]-14--4--3- - Google Patents

Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro- 4-oxoquinoline-3-carboxamide n-[24-(11-)-5-]-14--4--3-

Info

Publication number
HK1125540A1
HK1125540A1 HK09104028.9A HK09104028A HK1125540A1 HK 1125540 A1 HK1125540 A1 HK 1125540A1 HK 09104028 A HK09104028 A HK 09104028A HK 1125540 A1 HK1125540 A1 HK 1125540A1
Authority
HK
Hong Kong
Prior art keywords
oxoquinoline
dimethylethyl
carboxamide
hydroxyphenyl
dihydro
Prior art date
Application number
HK09104028.9A
Other languages
English (en)
Chinese (zh)
Inventor
．哈特
．羅維
．容
．考斯塔克
．康納利
．科拉維克
．宮
．馮
．特魯多
Original Assignee
沃泰克斯藥物股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38228833&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1125540(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 沃泰克斯藥物股份有限公司 filed Critical 沃泰克斯藥物股份有限公司
Publication of HK1125540A1 publication Critical patent/HK1125540A1/xx

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
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    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

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  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicinal Preparation (AREA)
HK09104028.9A 2005-12-28 2009-04-30 Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro- 4-oxoquinoline-3-carboxamide n-[24-(11-)-5-]-14--4--3- HK1125540A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75438105P 2005-12-28 2005-12-28
PCT/US2006/049421 WO2007079139A2 (en) 2005-12-28 2006-12-28 Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide

Publications (1)

Publication Number Publication Date
HK1125540A1 true HK1125540A1 (en) 2009-08-14

Family

ID=38228833

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09104028.9A HK1125540A1 (en) 2005-12-28 2009-04-30 Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro- 4-oxoquinoline-3-carboxamide n-[24-(11-)-5-]-14--4--3-

Country Status (20)

Country Link
US (9) US20110064811A1 (lt)
EP (3) EP3708564B1 (lt)
JP (3) JP5409010B2 (lt)
CN (1) CN101384172B (lt)
AU (1) AU2006332726B2 (lt)
BR (1) BRPI0620960A2 (lt)
CA (1) CA2635581C (lt)
CY (2) CY1118980T1 (lt)
DK (2) DK3219705T3 (lt)
ES (2) ES2790700T3 (lt)
HK (1) HK1125540A1 (lt)
HR (2) HRP20170682T1 (lt)
HU (2) HUE049976T2 (lt)
LT (2) LT3219705T (lt)
ME (1) ME03786B (lt)
PL (2) PL3219705T3 (lt)
PT (2) PT3219705T (lt)
RS (2) RS60205B1 (lt)
SI (1) SI3219705T1 (lt)
WO (1) WO2007079139A2 (lt)

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CA2696298C (en) 2007-08-24 2016-09-06 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
CA2699292A1 (en) * 2007-09-14 2009-03-26 Vertex Pharmaceuticals Incorporated Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
EP3012250B1 (en) 2007-11-16 2017-11-08 Vertex Pharmaceuticals Incorporated Isoquinoline modulators of atp-binding cassette transporters
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EP3683218B1 (en) 2007-12-07 2024-09-18 Vertex Pharmaceuticals Incorporated Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid
JP2011506331A (ja) * 2007-12-07 2011-03-03 バーテックス ファーマシューティカルズ インコーポレイテッド ３−（６−（１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）シクロプロパンカルボキサミド）−３−メチルピリジン−２−イル）安息香酸の処方物
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CA2931134C (en) 2008-02-28 2019-07-30 Vertex Pharmaceuticals Incorporated Heteroaryl derivatives as cftr modulators
CN101959856A (zh) * 2008-03-11 2011-01-26 雷迪博士实验室有限公司 来那度胺的制备
SI2615085T1 (sl) 2008-03-31 2015-11-30 Vertex Pharmaceuticals Incorporated Piridilni derivati kot cftr-modulatorji
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JP2012504143A (ja) * 2008-09-29 2012-02-16 バーテックス ファーマシューティカルズ インコーポレイテッド ３−（６−（１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）シクロプロパンカルボキサミド）−３−メチルピリジン−２−イル）安息香酸の用量単位
MX2011004374A (es) * 2008-10-23 2011-05-23 Vertex Pharma Formas solidas de n-(4-(7-azabiciclo[2.2.1]heptan-7-il)-2-(trifluo rometil)fenil)-4-oxo-5-(trifluorometil)-1,4-dihidroquinolin-3-car boxamida.
NZ592687A (en) * 2008-10-23 2013-04-26 Vertex Pharma Modulators of cystic fibrosis transmembrane conductance regulator
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US20140242172A1 (en) 2014-08-28
EP1993360B1 (en) 2017-02-08
AU2006332726B2 (en) 2012-12-13
US20110064811A1 (en) 2011-03-17
AU2006332726A1 (en) 2007-07-12
US8754224B2 (en) 2014-06-17
CA2635581C (en) 2017-02-28
WO2007079139A2 (en) 2007-07-12
US20210251978A9 (en) 2021-08-19
US11291662B2 (en) 2022-04-05
US20160229806A1 (en) 2016-08-11

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