ZA986594B - Urokinase inhibitors - Google Patents

Urokinase inhibitors

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Publication number
ZA986594B
ZA986594B ZA986594A ZA986594A ZA986594B ZA 986594 B ZA986594 B ZA 986594B ZA 986594 A ZA986594 A ZA 986594A ZA 986594 A ZA986594 A ZA 986594A ZA 986594 B ZA986594 B ZA 986594B
Authority
ZA
South Africa
Prior art keywords
urokinase inhibitors
urokinase
inhibitors
Prior art date
Application number
ZA986594A
Inventor
Andrew G Geyer
William J Mcclellan
Todd W Rockway
Kent D Stewart
Moshe Weitzberg
Michael D Wendt
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA986594B publication Critical patent/ZA986594B/en

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    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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    • A61P15/18—Feminine contraceptives
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    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
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