BR9507788A - Composto ou solvato ou sal do mesmo processo para a preparação do composto composição farmacêutica antagonista do receptor de NK3 uso do composto uso do antagonista do receptor de NG3 e processo para o tratamento e/ou profilaxia de distúrbios pulmonares e distúrbios convulsivos - Google Patents
Composto ou solvato ou sal do mesmo processo para a preparação do composto composição farmacêutica antagonista do receptor de NK3 uso do composto uso do antagonista do receptor de NG3 e processo para o tratamento e/ou profilaxia de distúrbios pulmonares e distúrbios convulsivosInfo
- Publication number
- BR9507788A BR9507788A BR9507788A BR9507788A BR9507788A BR 9507788 A BR9507788 A BR 9507788A BR 9507788 A BR9507788 A BR 9507788A BR 9507788 A BR9507788 A BR 9507788A BR 9507788 A BR9507788 A BR 9507788A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- receptor antagonist
- disorders
- prophylaxis
- solvate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Ceramic Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Structural Engineering (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Materials Engineering (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Anesthesiology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT94MI001099A ITMI941099A1 (it) | 1994-05-27 | 1994-05-27 | Derivati chinolinici |
ITMI950494 IT1293558B1 (it) | 1995-03-14 | 1995-03-14 | Derivati chinolinici |
PCT/EP1995/002000 WO1995032948A1 (en) | 1994-05-27 | 1995-05-23 | Quinoline derivatives as tachykinin nk3 receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9507788A true BR9507788A (pt) | 1997-09-23 |
Family
ID=26331143
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9507788A BR9507788A (pt) | 1994-05-27 | 1995-05-23 | Composto ou solvato ou sal do mesmo processo para a preparação do composto composição farmacêutica antagonista do receptor de NK3 uso do composto uso do antagonista do receptor de NG3 e processo para o tratamento e/ou profilaxia de distúrbios pulmonares e distúrbios convulsivos |
Country Status (35)
Country | Link |
---|---|
US (5) | US6608083B1 (pt) |
EP (2) | EP0804419B1 (pt) |
JP (5) | JP3664492B2 (pt) |
KR (1) | KR100316571B1 (pt) |
CN (3) | CN1092642C (pt) |
AP (1) | AP578A (pt) |
AR (1) | AR037069A2 (pt) |
AT (2) | ATE273959T1 (pt) |
AU (1) | AU699319B2 (pt) |
BG (2) | BG64004B1 (pt) |
BR (1) | BR9507788A (pt) |
CA (1) | CA2191352C (pt) |
CZ (1) | CZ291476B6 (pt) |
DE (2) | DE69533408T2 (pt) |
DK (1) | DK0804419T3 (pt) |
DZ (1) | DZ1889A1 (pt) |
ES (2) | ES2227769T3 (pt) |
FI (2) | FI115052B (pt) |
HK (2) | HK1003884A1 (pt) |
HU (1) | HU226535B1 (pt) |
IL (1) | IL113844A (pt) |
MA (1) | MA23560A1 (pt) |
MX (1) | MX9605903A (pt) |
MY (1) | MY129596A (pt) |
NO (2) | NO307783B1 (pt) |
NZ (1) | NZ287442A (pt) |
OA (1) | OA10592A (pt) |
PL (2) | PL186665B1 (pt) |
PT (2) | PT940391E (pt) |
RO (1) | RO114445B1 (pt) |
SA (1) | SA95160290B1 (pt) |
SK (2) | SK282722B6 (pt) |
TW (2) | TW533199B (pt) |
UA (1) | UA51623C2 (pt) |
WO (1) | WO1995032948A1 (pt) |
Families Citing this family (92)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2227769T3 (es) * | 1994-05-27 | 2005-04-01 | Glaxosmithkline S.P.A. | Derivados de quinolina como antagonistas del receptor nk3 de taquiquinina. |
AR004735A1 (es) * | 1995-11-24 | 1999-03-10 | Smithkline Beecham Spa | Quinoleina 4-amido sustituida, un procedimiento para su preparacion, una composicion farmaceutica que los contiene y el uso de los mismos para lapreparacion de un medicamento. |
IL124522A0 (en) * | 1995-11-24 | 1998-12-06 | Smithkline Beecham Spa | Quinoline derivatives |
GB9524137D0 (en) | 1995-11-24 | 1996-01-24 | Smithkline Beecham Spa | Novel compounds |
AU757836B2 (en) * | 1995-11-24 | 2003-03-06 | Smithkline Beecham Spa | Quinoline derivatives |
GB9524104D0 (en) * | 1995-11-24 | 1996-01-24 | Smithkline Beecham Spa | Novel compounds |
WO1998041506A1 (en) * | 1997-03-14 | 1998-09-24 | Smithkline Beecham Corporation | Novel quinoline- and naphthalenecarboxamides, pharmaceutical compositions and methods of inhibiting calpain |
US6077850A (en) * | 1997-04-21 | 2000-06-20 | G.D. Searle & Co. | Substituted benzopyran analogs for the treatment of inflammation |
HUP0002300A3 (en) * | 1997-05-23 | 2002-01-28 | Smithkline Beecham Spa | Quinoline-4-carboxamide derivatives, process for producing them, pharmaceutical compositions containing them and their use |
US20010012846A1 (en) * | 1997-05-23 | 2001-08-09 | Glardina Giuseppe Arnaldo Maria | Quinoline-4-carboxamide derivatives as NK-2 and NK-3 receptor antagonists |
EP1652840A3 (en) * | 1997-09-17 | 2006-05-17 | Smithkline Beecham Corporation | (-)-(S)-N-(.alpha.-ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carboxamide |
AP1201A (en) * | 1997-09-17 | 2003-09-01 | Smithkline Beecham Corp | Method for the synthesis of quinoline derivatives. |
US6083944A (en) * | 1997-10-07 | 2000-07-04 | Cephalon, Inc. | Quinoline-containing α-ketoamide cysteine and serine protease inhibitors |
GB9825554D0 (en) * | 1998-11-20 | 1999-01-13 | Smithkline Beecham Spa | Novel Compounds |
US6780875B2 (en) * | 1998-11-20 | 2004-08-24 | Smithkline Beecham S.P.A. | Quinoline-4-carboxamide derivatives as NK-3 and NK-2 receptor antagonists |
IL143137A0 (en) * | 1998-11-20 | 2002-04-21 | Smithkline Beecham Spa | Quinoline-4-carboxamide derivatives as nk-3 and nk-2 receptor antagonists |
JP2002535274A (ja) * | 1999-01-25 | 2002-10-22 | スミスクライン・ビーチャム・コーポレイション | 抗アンドロゲン剤および疾病の治療方法 |
US7037922B1 (en) | 2000-03-10 | 2006-05-02 | Neurogen Corporation | Aryl fused 2,4-disubstituted pyridines: NK3 receptor ligands |
JP2002540203A (ja) | 1999-03-29 | 2002-11-26 | ニューロゲン コーポレイション | Nk−3および/またはgaba(a)受容体リガンドとしての4−置換キノリン誘導体 |
WO2000064877A1 (en) | 1999-04-26 | 2000-11-02 | Neurogen Corporation | 2-aminoquinolinecarboxamides: neurokinin receptor ligands |
US6521618B2 (en) | 2000-03-28 | 2003-02-18 | Wyeth | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors |
WO2002013825A1 (en) * | 2000-08-11 | 2002-02-21 | Smithkline Beecham P.L.C. | Novel pharmaceutical use of quinnoline derivatives |
GB0028964D0 (en) * | 2000-11-28 | 2001-01-10 | Smithkline Beecham Spa | Novel compounds |
US6540733B2 (en) * | 2000-12-29 | 2003-04-01 | Corazon Technologies, Inc. | Proton generating catheters and methods for their use in enhancing fluid flow through a vascular site occupied by a calcified vascular occlusion |
US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
DE60209362T2 (de) * | 2001-04-11 | 2006-10-26 | Glaxosmithkline S.P.A. | 3-substituierte chinolin-4-carbonsäureamidderivate als nk-3- und nk-2-rezeptorantagonisten |
US20040152727A1 (en) * | 2001-05-18 | 2004-08-05 | Hay Douglas William Pierre | Novel use |
CA2493854A1 (en) * | 2002-06-26 | 2004-01-08 | Kyowa Hakko Kogyo Co., Ltd. | Phosphodiesterase inhibitor |
GB0228288D0 (en) * | 2002-12-04 | 2003-01-08 | Smithkline Beecham Corp | Chemical compounds |
GB0228287D0 (en) * | 2002-12-04 | 2003-01-08 | Smithkline Beecham Corp | Chemical compounds |
GB0312609D0 (en) | 2003-06-02 | 2003-07-09 | Astrazeneca Ab | Novel compounds |
SE0302139D0 (sv) * | 2003-07-28 | 2003-07-28 | Astrazeneca Ab | Novel compounds |
JP4901480B2 (ja) | 2003-12-22 | 2012-03-21 | グラクソ グループ リミテッド | 神経疾患治療用の、nogo−aを中和する免疫グロブリン |
AU2005214159A1 (en) | 2004-02-04 | 2005-09-01 | Pfizer Products Inc. | Substituted quinoline compounds |
US20070244152A1 (en) * | 2004-03-25 | 2007-10-18 | Lowy Martin T | Use of an Nk3 Antagonist for the Treatment of Bipolar Disorders |
BRPI0508111A (pt) * | 2004-03-30 | 2007-07-17 | Smithkline Beecham Corp | composições farmacêuticas secas por aspersão |
PL1773816T3 (pl) | 2004-06-24 | 2015-06-30 | Vertex Pharma | Modulatory transporterów posiadających kasetę wiążącą ATP |
US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
GB0417559D0 (en) * | 2004-08-06 | 2004-09-08 | Merck Sharp & Dohme | Therapeutic compounds |
GB0417560D0 (en) * | 2004-08-06 | 2004-09-08 | Merck Sharp & Dohme | Therapeutic compounds |
GB0425075D0 (en) * | 2004-11-12 | 2004-12-15 | Smithkline Beecham Corp | Novel compounds |
GB0425076D0 (en) * | 2004-11-12 | 2004-12-15 | Smithkline Beecham Corp | Novel compounds |
GB0425077D0 (en) * | 2004-11-12 | 2004-12-15 | Smithkline Beecham Corp | Novel compounds |
GB0428233D0 (en) * | 2004-12-23 | 2005-01-26 | Glaxo Group Ltd | Compounds |
US20080200500A1 (en) * | 2005-06-03 | 2008-08-21 | Astrazeneca Ab | Quinoline Derivatives as Nk3 Antagonists |
CA2613001A1 (en) * | 2005-06-23 | 2006-12-28 | Astrazeneca Ab | Quinoline 3 -sulfonate esters as nk3 receptor modulators |
GB0515580D0 (en) | 2005-07-29 | 2005-09-07 | Merck Sharp & Dohme | Therapeutic compounds |
US20080194623A1 (en) * | 2005-08-02 | 2008-08-14 | Labaw Clifford S | Method for the Synthesis of Quinoline Derivatives |
JP2009504640A (ja) * | 2005-08-11 | 2009-02-05 | アストラゼネカ・アクチエボラーグ | Nk−3受容体の調節剤としてのアミドアルキルピリジルキノリン |
EP1915363A1 (en) * | 2005-08-11 | 2008-04-30 | AstraZeneca AB | Oxopyridyl quinoline amides as nk3 receptor modulators |
AR058051A1 (es) * | 2005-09-21 | 2008-01-23 | Astrazeneca Ab | Quinolinas de alquilnitrilo.proceso de obtencion y composiciones farmaceuticas. |
CN101268052A (zh) * | 2005-09-21 | 2008-09-17 | 阿斯利康(瑞典)有限公司 | 作为nk-3受体配体的n-氧代-杂环和n-氧代-烷基喹啉-4-甲酰胺 |
AR057130A1 (es) * | 2005-09-21 | 2007-11-14 | Astrazeneca Ab | Quinolinas de alquilsulfoxido y una composicion farmaceutica |
TW200804288A (en) | 2005-12-12 | 2008-01-16 | Astrazeneca Ab | Alkylsulphonamide quinolines |
GB0525662D0 (en) | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Immunoglobulins |
JP2009521468A (ja) * | 2005-12-24 | 2009-06-04 | バーテックス ファーマシューティカルズ インコーポレイテッド | Abc輸送体の調節因子としてのキノリン−4−オン誘導体 |
HUE049976T2 (hu) * | 2005-12-28 | 2020-11-30 | Vertex Pharma | N-[2,4-bisz(1,1-dimetil-etil)-5-hidroxi-fenil]-1,4-dihidro-4-oxo-kinolin-3-karboxamid amorf alakjának gyógyászati kompozíciói |
WO2007086799A1 (en) * | 2006-01-27 | 2007-08-02 | Astrazeneca Ab | Amide substituted quinolines |
GB0603087D0 (en) * | 2006-02-15 | 2006-03-29 | Glaxo Group Ltd | Novel use |
CA2680761A1 (en) | 2007-03-22 | 2008-09-25 | Astrazeneca Ab | Quinoline derivatives for the treatment of inflammatory diseases |
US8173639B2 (en) | 2007-04-26 | 2012-05-08 | H. Lundbeck A/S | Isoquinolinone derivatives as NK3 antagonists |
WO2008131779A1 (en) * | 2007-04-26 | 2008-11-06 | H. Lundbeck A/S | Isoquinolinone derivatives as nk3 antagonists |
JP2010536872A (ja) * | 2007-08-22 | 2010-12-02 | アラーガン、インコーポレイテッド | 治療用キノリンおよびナフタレン誘導体 |
WO2009049791A2 (en) * | 2007-10-15 | 2009-04-23 | F. Hoffmann-La Roche Ag | Radiolabeled nk3 receptor antagonist |
US8106073B2 (en) | 2007-11-30 | 2012-01-31 | Astrazeneca Ab | Quinoline derivatives 057 |
MX2010013868A (es) * | 2008-06-23 | 2011-02-24 | Lundbeck & Co As H | Derivados de isoquinolinona como antagonistas de nk3. |
US8242134B2 (en) | 2008-09-15 | 2012-08-14 | H. Lundbeck A/S | Isoquinolinone derivatives as NK3 antagonists |
WO2010045948A1 (en) | 2008-10-20 | 2010-04-29 | H. Lundbeck A/S | Isoquinolinone derivatives as nk3 antagonists |
KR101852173B1 (ko) | 2009-03-20 | 2018-04-27 | 버텍스 파마슈티칼스 인코포레이티드 | 낭성 섬유증 막횡단 전도도 조절자의 조정자의 제조 방법 |
TW201143768A (en) | 2009-12-15 | 2011-12-16 | Lundbeck & Co As H | Pyridone derivatives as NK3 antagonists |
TW201144311A (en) | 2010-03-12 | 2011-12-16 | Lundbeck & Co As H | Azaisoquionolinone derivatives as NK3 antagonists |
US8487102B2 (en) * | 2010-04-20 | 2013-07-16 | Hoffmann-La Roche Inc. | Pyrrazolopyridine compounds as dual NK1/NK3 receptor antagonists |
US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
EP2804859B1 (en) | 2012-01-17 | 2019-06-12 | Universiteit Antwerpen | Novel fap inhibitors |
BR112014021090B1 (pt) | 2012-02-27 | 2023-01-24 | Vertex Pharmaceuticals Incorporated | Composição farmacêutica e uso de n-[2,4-bis(1,1-dimetiletil)-5-hidróxifenil]-1,4-di-hidro-4-oxoquinolina3-carboxamida na preparação da mesma |
CN102702099A (zh) * | 2012-06-21 | 2012-10-03 | 江苏恩华药业股份有限公司 | (s)-3-羟基-2-苯基-n-(1-苯基丙基)喹啉-4-甲酰胺的制备方法 |
CA2909752A1 (en) | 2013-04-19 | 2014-10-23 | Astrazeneca Ab | A nk3 receptor antagonist compound (nk3ra) for use in a method for the treatment of polycystic ovary syndrome (pcos) |
EP3915560A1 (en) | 2014-06-25 | 2021-12-01 | Emory University | Methods of managing conditioned fear with neurokinin receptor antagonists |
WO2016004035A1 (en) * | 2014-07-01 | 2016-01-07 | Icahn School Of Medicine At Mount Sinai | 2-aryl-4-quinolinecarboxamide derivatives for treating thyroid diseases |
WO2016037954A1 (de) | 2014-09-09 | 2016-03-17 | Bayer Pharma Aktiengesellschaft | Substituierte n,2-diarylchinolin-4-carboxamide und ihre anti-inflammatorische verwendung |
KR20170063954A (ko) | 2014-10-07 | 2017-06-08 | 버텍스 파마슈티칼스 인코포레이티드 | 낭성 섬유증 막횡단 전도도 조절자의 조정제의 공-결정 |
JP2018512404A (ja) | 2015-03-18 | 2018-05-17 | バイエル ファーマ アクチエンゲゼルシャフト | 置換n−ビシクロ−2−アリール−キノリン−4−カルボキサミドおよびその使用 |
ES2753539T3 (es) * | 2015-05-18 | 2020-04-13 | Nerre Therapeutics Ltd | Antagonista del receptor NK-1/NK-3 para el tratamiento de los sofocos |
WO2017072629A1 (en) | 2015-10-29 | 2017-05-04 | Cadila Healthcare Limited | Pharmaceutical combination of nk3 receptor antagonist and biguanides |
WO2017153231A1 (de) | 2016-03-09 | 2017-09-14 | Bayer Pharma Aktiengesellschaft | Substituierte n-cyclo-2-arylisochinolinon-4-carboxamide und ihre verwendung |
WO2017153235A1 (de) | 2016-03-09 | 2017-09-14 | Bayer Pharma Aktiengesellschaft | Substituierte n-cyclo-3-aryl-1-naphthamide und ihre verwendung |
WO2017153234A1 (de) | 2016-03-09 | 2017-09-14 | Bayer Pharma Aktiengesellschaft | Substituierte n-cyclo-2-arylchinolin-4-carboxamide und ihre verwendung |
CN105884626B (zh) * | 2016-05-04 | 2017-10-20 | 龙曦宁(上海)医药科技有限公司 | 一种2‑氨基茚满衍生物的合成方法及其产品 |
CA3059273A1 (en) * | 2017-04-10 | 2018-10-18 | Bayer Aktiengesellschaft | Substituted n-arylethyl-2-arylquinoline-4-carboxamides and use thereof |
TWI770157B (zh) | 2017-04-10 | 2022-07-11 | 德商拜耳廠股份有限公司 | 經取代之n-芳基乙基-2-胺基喹啉-4-甲醯胺及其用途 |
US11458129B2 (en) | 2017-11-02 | 2022-10-04 | California Institute Of Technology | Neurokinin antagonists and uses thereof |
EP3881843A4 (en) * | 2018-11-15 | 2022-08-03 | Kyushu University, National University Corporation | PROPHYLACTIC OR THERAPEUTIC AGENT AND MEDICAL COMPOSITION FOR IL-31 MEDIATED DISEASE |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1560489A (en) * | 1976-05-21 | 1980-02-06 | Fisons Ltd | Pharmaceutical compositions |
FR2538388B1 (fr) * | 1982-12-24 | 1985-06-21 | Pharmuka Lab | Nouveaux derives de naphtalene- ou azanaphtalenecarboxamide, leurs procedes de preparation et leur utilisation comme medicaments |
DE3905339A1 (de) * | 1989-02-22 | 1990-09-06 | Basf Ag | Chinolin-4-carbonsaeurederivate und deren verwendung |
US4992448A (en) * | 1989-10-24 | 1991-02-12 | Hoechst-Roussel Pharmaceuticals Inc. | Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders |
US5037835A (en) * | 1989-10-24 | 1991-08-06 | Hoechst-Roussel Pharmaceuticals Inc. | Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders |
DE69126058T2 (de) * | 1990-03-26 | 1997-09-25 | Matsushita Electric Ind Co Ltd | Lichtempfindliches Material für Elektrophotographie |
ATE161530T1 (de) * | 1992-09-04 | 1998-01-15 | Takeda Chemical Industries Ltd | Kondensierte heterozyklische verbindungen, deren herstellung und verwendung |
US5434158A (en) * | 1994-04-26 | 1995-07-18 | Merck & Co., Inc. | Spiro-substituted azacycles as neurokinin-3 antagonists |
ES2227769T3 (es) | 1994-05-27 | 2005-04-01 | Glaxosmithkline S.P.A. | Derivados de quinolina como antagonistas del receptor nk3 de taquiquinina. |
US5607936A (en) * | 1994-09-30 | 1997-03-04 | Merck & Co., Inc. | Substituted aryl piperazines as neurokinin antagonists |
-
1995
- 1995-05-23 ES ES98204483T patent/ES2227769T3/es not_active Expired - Lifetime
- 1995-05-23 AT AT98204483T patent/ATE273959T1/de not_active IP Right Cessation
- 1995-05-23 SK SK47-99A patent/SK282722B6/sk not_active IP Right Cessation
- 1995-05-23 EP EP95920894A patent/EP0804419B1/en not_active Expired - Lifetime
- 1995-05-23 JP JP50028796A patent/JP3664492B2/ja not_active Expired - Fee Related
- 1995-05-23 DE DE69533408T patent/DE69533408T2/de not_active Expired - Lifetime
- 1995-05-23 PL PL95341889A patent/PL186665B1/pl not_active IP Right Cessation
- 1995-05-23 PL PL95317381A patent/PL186075B1/pl not_active IP Right Cessation
- 1995-05-23 EP EP98204483A patent/EP0940391B1/en not_active Expired - Lifetime
- 1995-05-23 CN CN95194338A patent/CN1092642C/zh not_active Expired - Fee Related
- 1995-05-23 DK DK95920894T patent/DK0804419T3/da active
- 1995-05-23 AU AU26164/95A patent/AU699319B2/en not_active Ceased
- 1995-05-23 ES ES95920894T patent/ES2204952T3/es not_active Expired - Lifetime
- 1995-05-23 SK SK1514-96A patent/SK282721B6/sk not_active IP Right Cessation
- 1995-05-23 PT PT98204483T patent/PT940391E/pt unknown
- 1995-05-23 RO RO96-02234A patent/RO114445B1/ro unknown
- 1995-05-23 NZ NZ287442A patent/NZ287442A/en not_active IP Right Cessation
- 1995-05-23 HU HU9603262A patent/HU226535B1/hu not_active IP Right Cessation
- 1995-05-23 UA UA96124918A patent/UA51623C2/uk unknown
- 1995-05-23 WO PCT/EP1995/002000 patent/WO1995032948A1/en active IP Right Grant
- 1995-05-23 PT PT95920894T patent/PT804419E/pt unknown
- 1995-05-23 BR BR9507788A patent/BR9507788A/pt not_active IP Right Cessation
- 1995-05-23 KR KR1019960706701A patent/KR100316571B1/ko not_active IP Right Cessation
- 1995-05-23 DE DE69531458T patent/DE69531458T2/de not_active Expired - Lifetime
- 1995-05-23 CA CA002191352A patent/CA2191352C/en not_active Expired - Fee Related
- 1995-05-23 CZ CZ19963470A patent/CZ291476B6/cs not_active IP Right Cessation
- 1995-05-23 AT AT95920894T patent/ATE246677T1/de not_active IP Right Cessation
- 1995-05-24 DZ DZ950061A patent/DZ1889A1/fr active
- 1995-05-24 AP APAP/P/1995/000745A patent/AP578A/en active
- 1995-05-25 US US08/450,437 patent/US6608083B1/en not_active Expired - Fee Related
- 1995-05-25 MA MA23898A patent/MA23560A1/fr unknown
- 1995-05-25 MY MYPI95001381A patent/MY129596A/en unknown
- 1995-05-25 IL IL11384495A patent/IL113844A/xx not_active IP Right Cessation
- 1995-05-25 US US08/450,438 patent/US5811553A/en not_active Expired - Lifetime
- 1995-05-26 TW TW088121625A patent/TW533199B/zh not_active IP Right Cessation
- 1995-05-26 TW TW084105319A patent/TW427977B/zh not_active IP Right Cessation
- 1995-10-03 SA SA95160290A patent/SA95160290B1/ar unknown
-
1996
- 1996-11-25 BG BG101008A patent/BG64004B1/bg unknown
- 1996-11-26 MX MX9605903A patent/MX9605903A/es not_active IP Right Cessation
- 1996-11-26 NO NO965036A patent/NO307783B1/no unknown
- 1996-11-26 FI FI964712A patent/FI115052B/fi active IP Right Grant
- 1996-11-27 OA OA60928A patent/OA10592A/en unknown
-
1998
- 1998-04-09 HK HK98103021A patent/HK1003884A1/xx not_active IP Right Cessation
-
1999
- 1999-01-15 CN CN99100978A patent/CN1276211A/zh active Pending
- 1999-02-10 FI FI990268A patent/FI119721B/fi active IP Right Grant
- 1999-02-16 BG BG103181A patent/BG103181A/bg unknown
- 1999-04-16 NO NO991813A patent/NO326714B1/no unknown
- 1999-06-18 JP JP11172597A patent/JP2000026314A/ja active Pending
-
2000
- 2000-03-06 HK HK00101401A patent/HK1024469A1/xx not_active IP Right Cessation
- 2000-06-22 AR ARP000103117A patent/AR037069A2/es unknown
-
2001
- 2001-05-29 US US09/867,133 patent/US20030236281A1/en not_active Abandoned
- 2001-10-24 JP JP2001326622A patent/JP2002179594A/ja active Pending
-
2002
- 2002-03-18 CN CN02107941A patent/CN1428145A/zh active Pending
-
2004
- 2004-09-30 JP JP2004287629A patent/JP2005068155A/ja active Pending
- 2004-11-29 US US10/999,180 patent/US20050096316A1/en not_active Abandoned
-
2006
- 2006-03-21 US US11/385,461 patent/US7482458B2/en not_active Expired - Fee Related
- 2006-12-28 JP JP2006355694A patent/JP2007126475A/ja not_active Ceased
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9507788A (pt) | Composto ou solvato ou sal do mesmo processo para a preparação do composto composição farmacêutica antagonista do receptor de NK3 uso do composto uso do antagonista do receptor de NG3 e processo para o tratamento e/ou profilaxia de distúrbios pulmonares e distúrbios convulsivos | |
BR9609467A (pt) | Composto uso de um composto composição farmacéutica e processos para preparação de um composto e tratamento de distúrbios de agregação planquetária | |
BR9406128A (pt) | Uso de um composto processo para o tratamento e/ou prevençao de distúrbios psicóticos composto composiçao farmacêutica processos para a preparaçao de um composto e de uma composiçao farmacêutica | |
BR9406566A (pt) | Composição farmacêutica uso de progesterona e/ou 17 - - estradiol e processo para a fabricação de uma preparação farmacêutica | |
BR9404203A (pt) | Compostos, processo para a preparação dos mesmos, medicamento, uso dos ditos compostos e processo de tratamento ou prevenção de distúrbios nervosos centrais | |
BR9612204A (pt) | Composto uso do composto composição farmacêutica e processo para preparação do composto e para o tratamento de dor | |
BR9602705A (pt) | Composto composição farmacéutica processo para a preparação de um composto e uso | |
BR9812886A (pt) | Uso de um atagonista de recptor de 5-ht3 ou de um seu derivado farmaceuticamente aceitável, processo para tratamento de ibs em fêmeas não-constipadas, e, antagonista de recpetor de 5-ht3 ou seu derivado farmaceuticamente aceitável | |
BR9708093A (pt) | Composto formulação uso composto e processo para tratamento de distúrbios mediados por 5-hidroxitriptamina e para preparação do composto | |
BR9505107A (pt) | Composto composiçao farmacêutica processo para a preparaçao de um composto e seu uso | |
AR241161A1 (es) | "procedimiento para la preparacion de derivados n-aminoalquilen sustituidos de la glutarimida" | |
HUP9902405A3 (en) | Pharmaceutical compositions containing a serotonin antagonist for the treatment of the common cold or allergic rhinitis | |
BR9504491A (pt) | Composto composiçao farmacêutica métodos para a inibiçao do tip IV de fosfodiesterase e de tratar ou prevenir um estado precário de saude | |
BR9708607A (pt) | Composto composição farmacéutica utilização de um composto processo para tratamento ou redução do risco de doença inflamatória num paciente e para a preparação de um composto e intermediário químico | |
BR9506581A (pt) | Composto composição farmacêutica uso do composto processo para a profilaxia ou tratamento de uma condição clínica em um manífero por exemplo um humano e para a preparação de um composto e composto intermediário | |
BR9607346A (pt) | Composto utilizaç o de um composto composiç o farmacéutica e processo para o tratamento de um mamifero e para e preparaç o de compostos | |
BR9710376A (pt) | Composto antiviral uso do mesmo composi-Æo farmac-utica e processo para tratamento antiviral profil tico ou terap-utico de um animal humano ou nÆo humano | |
BR9005793A (pt) | Composicao de fluoreto estanoso aquoso estabilizada e processo para preparacao da mesma | |
BR9507980A (pt) | Composto composição farmacêutica para uso no tratamento e/ou profilaxia de ansiedade mania depressão desordens associadas com uma hemorragia subaracnóide ou choke neural processo de tratamento e/ou profilaxia de ansiedade mania depressão desordens associadas com uma hemorragia subaracnóide ou choque neural composição farmacêutica uso de um composto | |
MX9205455A (es) | Procedimiento para la preparacion de diritromicina cristalina | |
BR9800557A (pt) | Processo contínuo para preparação de 4-aminopiperidinas | |
BR9610316A (pt) | Composto processo para a produção e uso do mesmo processo para o tratamento de doença das vias aéreas e composição farmacêutica | |
FI972306A0 (fi) | Substituoituja 2-aryylikarbonyylioksimetyyli-1,2,5-tiadiatsolidin -3- oni-1,1-dioksidi-johdannaisia ja niitä sisältäviä koostumuksia ja menetelmiä niiden käyttämiseksi | |
BR9606766A (pt) | Utilização de compostos e processo para o tratamento e profilaxia de disturbios degenerativos cerebrais | |
IT1246418B (it) | Regolazione rapida delle ganasce per utensili e simili |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
HJEG | Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law | ||
FF | Decision: intention to grant | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
B25A | Requested transfer of rights approved |
Owner name: GLAXO WELLCOME S.P.A. (IT) Free format text: TRANSFERIDO DE: SMITHKLINE BEECHAM S.P.A. |
|
B25D | Requested change of name of applicant approved |
Owner name: GLAXOSMITHKLINE S.P.A. (IT) Free format text: NOME ALTERADO DE: GLAXO WELLCOME S.P.A. |
|
B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 23/05/2015 |