EA201500417A1 - Композиции антагонистов pd-1 и способы применения - Google Patents

Композиции антагонистов pd-1 и способы применения

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Publication number
EA201500417A1
EA201500417A1 EA201500417A EA201500417A EA201500417A1 EA 201500417 A1 EA201500417 A1 EA 201500417A1 EA 201500417 A EA201500417 A EA 201500417A EA 201500417 A EA201500417 A EA 201500417A EA 201500417 A1 EA201500417 A1 EA 201500417A1
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Eurasian Patent Office
Prior art keywords
applications
methods
antagonist compositions
compositions
potentiating
Prior art date
Application number
EA201500417A
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English (en)
Inventor
Соломон Ланджерман
Линда Лью
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Эмплиммьюн, Инк.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41725778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201500417(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Эмплиммьюн, Инк. filed Critical Эмплиммьюн, Инк.
Publication of EA201500417A1 publication Critical patent/EA201500417A1/ru

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    • AHUMAN NECESSITIES
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    • A61K38/00Medicinal preparations containing peptides
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    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
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    • A61P35/00Antineoplastic agents
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
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    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Hematology (AREA)
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  • AIDS & HIV (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Abstract

Описаны способы лечения рака и инфекционных заболеваний с применением схемы лечения, включающей в себя введение соединения, которое уменьшает передачу ингибиторного сигнала в Т-клетки, в комбинации с потенцирующим агентом, таким как циклофосфамид, для получения эффективных Т-клеточно-опосредованных ответов. Также раскрыты композиции, включающие в себя антагонисты PD-1 и потенцирующие агенты, применяемые в способах изобретения.
EA201500417A 2008-08-25 2009-08-25 Композиции антагонистов pd-1 и способы применения EA201500417A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9170508P 2008-08-25 2008-08-25
US9170908P 2008-08-25 2008-08-25
US9169408P 2008-08-25 2008-08-25
US21169709P 2009-04-02 2009-04-02

Publications (1)

Publication Number Publication Date
EA201500417A1 true EA201500417A1 (ru) 2015-11-30

Family

ID=41725778

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201170373A EA023148B1 (ru) 2008-08-25 2009-08-25 Композиции на основе антагонистов pd-1 и их применение
EA201500417A EA201500417A1 (ru) 2008-08-25 2009-08-25 Композиции антагонистов pd-1 и способы применения

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA201170373A EA023148B1 (ru) 2008-08-25 2009-08-25 Композиции на основе антагонистов pd-1 и их применение

Country Status (28)

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US (4) US8114845B2 (ru)
EP (2) EP2350129B1 (ru)
JP (1) JP5798919B2 (ru)
KR (1) KR20110050529A (ru)
CN (1) CN102203132A (ru)
AU (1) AU2009288730B2 (ru)
CA (1) CA2734908A1 (ru)
CL (1) CL2011000423A1 (ru)
CO (1) CO6341574A2 (ru)
CY (1) CY1116816T1 (ru)
DK (1) DK2350129T3 (ru)
DO (1) DOP2011000059A (ru)
EA (2) EA023148B1 (ru)
ES (1) ES2545609T3 (ru)
HR (1) HRP20150933T1 (ru)
HU (1) HUE027525T2 (ru)
IL (1) IL211298A0 (ru)
MA (1) MA32646B1 (ru)
MX (1) MX2011002252A (ru)
NZ (1) NZ591130A (ru)
PE (1) PE20110435A1 (ru)
PL (1) PL2350129T3 (ru)
PT (1) PT2350129E (ru)
RS (1) RS54233B1 (ru)
SI (1) SI2350129T1 (ru)
SM (1) SMT201500212B (ru)
WO (1) WO2010027423A2 (ru)
ZA (1) ZA201101120B (ru)

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