PL2347775T3 - Rusztowania do przeszczepiania komórek - Google Patents
Rusztowania do przeszczepiania komórekInfo
- Publication number
- PL2347775T3 PL2347775T3 PL10194565T PL10194565T PL2347775T3 PL 2347775 T3 PL2347775 T3 PL 2347775T3 PL 10194565 T PL10194565 T PL 10194565T PL 10194565 T PL10194565 T PL 10194565T PL 2347775 T3 PL2347775 T3 PL 2347775T3
- Authority
- PL
- Poland
- Prior art keywords
- composition
- scaffolds
- cell transplantation
- scaffold
- bioactive
- Prior art date
Links
- 238000002054 transplantation Methods 0.000 title 1
- 230000000975 bioactive effect Effects 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000007115 recruitment Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001154—Enzymes
- A61K39/001156—Tyrosinase and tyrosinase related proteinases [TRP-1 or TRP-2]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001169—Tumor associated carbohydrates
- A61K39/00117—Mucins, e.g. MUC-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001169—Tumor associated carbohydrates
- A61K39/001171—Gangliosides, e.g. GM2, GD2 or GD3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00118—Cancer antigens from embryonic or fetal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00118—Cancer antigens from embryonic or fetal origin
- A61K39/001182—Carcinoembryonic antigen [CEA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
- A61K39/001186—MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
- A61K39/001191—Melan-A/MART
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
- A61K39/001192—Glycoprotein 100 [Gp100]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001193—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; PAP or PSGR
- A61K39/001195—Prostate specific membrane antigen [PSMA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3633—Extracellular matrix [ECM]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3826—Muscle cells, e.g. smooth muscle cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/426—Immunomodulating agents, i.e. cytokines, interleukins, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/438—Antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/30—Materials or treatment for tissue regeneration for muscle reconstruction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Developmental Biology & Embryology (AREA)
- Botany (AREA)
- Wood Science & Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74999805P | 2005-12-13 | 2005-12-13 | |
| US81413406P | 2006-06-16 | 2006-06-16 | |
| EP10194565.7A EP2347775B1 (en) | 2005-12-13 | 2006-12-13 | Scaffolds for cell transplantation |
| EP06847667A EP1960009B1 (en) | 2005-12-13 | 2006-12-13 | Scaffolds for cell transplantation |
| PCT/US2006/047823 WO2007070660A2 (en) | 2005-12-13 | 2006-12-13 | Scaffolds for cell transplantation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2347775T3 true PL2347775T3 (pl) | 2020-11-16 |
Family
ID=38163533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10194565T PL2347775T3 (pl) | 2005-12-13 | 2006-12-13 | Rusztowania do przeszczepiania komórek |
Country Status (13)
| Country | Link |
|---|---|
| US (8) | US8067237B2 (pl) |
| EP (3) | EP1960009B1 (pl) |
| JP (5) | JP5539649B2 (pl) |
| AT (1) | ATE534415T1 (pl) |
| AU (1) | AU2006326405B2 (pl) |
| CA (1) | CA2632630C (pl) |
| DK (1) | DK2347775T3 (pl) |
| ES (1) | ES2804472T3 (pl) |
| HU (1) | HUE051267T2 (pl) |
| PL (1) | PL2347775T3 (pl) |
| PT (1) | PT2347775T (pl) |
| SI (1) | SI2347775T1 (pl) |
| WO (1) | WO2007070660A2 (pl) |
Families Citing this family (147)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0630873Y2 (ja) | 1990-04-18 | 1994-08-17 | 村田機械株式会社 | 紡績装置 |
| EP1729675A4 (en) * | 2004-03-05 | 2011-05-18 | Univ Columbia | MULTI-PHASE BIODEGRADABLE AND EAST-INTEGRATIVE COMPOSITE SCULPTURE FOR THE BIOLOGICAL FIXATION OF SKELETAL MOLECULAR WEAVE ON BONE |
| US8153435B1 (en) | 2005-03-30 | 2012-04-10 | Tracer Detection Technology Corp. | Methods and articles for identifying objects using encapsulated perfluorocarbon tracers |
| WO2007070660A2 (en) | 2005-12-13 | 2007-06-21 | President And Fellows Of Harvard College | Scaffolds for cell transplantation |
| US7855062B2 (en) * | 2005-12-14 | 2010-12-21 | The Invention Science Fund I, Llc | Bone cell delivery device |
| US20110172826A1 (en) * | 2005-12-14 | 2011-07-14 | Amodei Dario G | Device including altered microorganisms, and methods and systems of use |
| US8354258B2 (en) | 2005-12-14 | 2013-01-15 | The Invention Science Fund I, Llc | Diatom device |
| US9005944B2 (en) * | 2005-12-14 | 2015-04-14 | The Invention Science Fund I, Llc | Bone cell delivery device |
| US8682619B2 (en) * | 2005-12-14 | 2014-03-25 | The Invention Science Fund I, Llc | Device including altered microorganisms, and methods and systems of use |
| US8900865B2 (en) * | 2005-12-14 | 2014-12-02 | The Invention Science Fund I, Llc | Blood brain barrier device |
| US8734823B2 (en) * | 2005-12-14 | 2014-05-27 | The Invention Science Fund I, Llc | Device including altered microorganisms, and methods and systems of use |
| US8278094B2 (en) | 2005-12-14 | 2012-10-02 | The Invention Science Fund I, Llc | Bone semi-permeable device |
| US20110183351A1 (en) * | 2010-01-22 | 2011-07-28 | Hyde Roderick A | Compositions and methods for therapeutic delivery with microorganisms |
| US9061075B2 (en) * | 2005-12-14 | 2015-06-23 | The Invention Science Fund I, Llc | Bone delivery device |
| EP1988942B1 (en) * | 2006-03-01 | 2011-07-27 | FMC Biopolymer AS | Gelled composite |
| US9485917B2 (en) | 2006-12-15 | 2016-11-08 | Ecovative Design, LLC | Method for producing grown materials and products made thereby |
| US8753391B2 (en) * | 2007-02-12 | 2014-06-17 | The Trustees Of Columbia University In The City Of New York | Fully synthetic implantable multi-phased scaffold |
| EP2152851B1 (en) * | 2007-04-06 | 2018-04-25 | Terumo BCT, Inc. | Improved bioreactor surfaces |
| WO2009002401A2 (en) | 2007-06-21 | 2008-12-31 | President And Fellows Of Harvard College | Scaffolds for cell collection or elimination |
| KR100932688B1 (ko) * | 2007-07-06 | 2009-12-21 | 한국과학기술연구원 | 인공혈관용 이중막 구조의 튜브형 다공성 스캐폴드 및 그의제조방법 |
| US20090081276A1 (en) * | 2007-08-13 | 2009-03-26 | Eben Alsberg | Bioresorbable implant composition |
| JP2009051773A (ja) * | 2007-08-27 | 2009-03-12 | Toyobo Co Ltd | 細胞接着能を有するhsp70ファミリータンパク質 |
| US8221744B2 (en) * | 2007-09-19 | 2012-07-17 | Abbott Cardiovascular Systems Inc. | Cytocompatible alginate gels |
| WO2009039378A2 (en) | 2007-09-19 | 2009-03-26 | The Charles Stark Draper Laboratory, Inc. | Microfluidic structures for biomedical applications |
| JP5589274B2 (ja) * | 2007-10-25 | 2014-09-17 | 東レ株式会社 | 免疫誘導剤 |
| US8198083B1 (en) | 2007-10-31 | 2012-06-12 | William Gunter Loudon | Organotypic slices of the central nervous system |
| WO2009102465A2 (en) * | 2008-02-13 | 2009-08-20 | President And Fellows Of Harvard College | Continuous cell programming devices |
| US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
| ES2641913T3 (es) * | 2008-03-27 | 2017-11-14 | Cleveland Clinic Foundation | Injerto de tejido reforzado |
| US20130116799A1 (en) | 2008-03-27 | 2013-05-09 | The Cleveland Clinic Foundation | Reinforced tissue graft |
| US8580564B2 (en) * | 2008-05-07 | 2013-11-12 | Ucl Business Plc | Biomimetic cell scaffolds |
| US9012399B2 (en) | 2008-05-30 | 2015-04-21 | President And Fellows Of Harvard College | Controlled release of growth factors and signaling molecules for promoting angiogenesis |
| US9127086B2 (en) * | 2008-06-30 | 2015-09-08 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | CD31 peptides in the treatment of thrombotic and autoimmune disorders |
| EP2196196A1 (en) * | 2008-12-10 | 2010-06-16 | Medipol S.A. | Compound, medicament, vaccine composition and nanocapsules |
| WO2010120749A2 (en) | 2009-04-13 | 2010-10-21 | President And Fellow Of Harvard College | Harnessing cell dynamics to engineer materials |
| US8551749B2 (en) * | 2009-04-23 | 2013-10-08 | The Invention Science Fund I, Llc | Device including bone cage and method for treatment of disease in a subject |
| US20150335400A1 (en) * | 2009-06-17 | 2015-11-26 | The Trustees Of Columbia University In The City Of New York | Tooth scaffolds |
| JP5750793B2 (ja) * | 2009-07-22 | 2015-07-22 | 国立大学法人信州大学 | Es細胞の継代方法及びes細胞増殖方法 |
| EP2461828B1 (en) | 2009-07-31 | 2017-06-21 | President and Fellows of Harvard College | Programming of cells for tolerogenic therapies |
| LT2470228T (lt) | 2009-08-28 | 2018-02-12 | Sernova Corporation | Būdai ir įrenginiai ląstelinei transplantacijai |
| WO2011109712A2 (en) * | 2010-03-04 | 2011-09-09 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Bioengineered human corneal stromal tissue |
| WO2011109834A2 (en) * | 2010-03-05 | 2011-09-09 | President And Fellows Of Harvard College | Enhancement of skeletal muscle stem cell engrafment by dual delivery of vegf and igf-1 |
| CN104606128B (zh) | 2010-03-29 | 2018-02-23 | 辉凌公司 | 一种快速溶解药物组合物 |
| JO3112B1 (ar) | 2010-03-29 | 2017-09-20 | Ferring Bv | تركيبة دوائية سريعة التحلل |
| US20130202564A1 (en) * | 2010-04-09 | 2013-08-08 | University Of Southern California | Systems and Methods of Cell Activated, Controlled Release Delivery of Growth Factors for Tissue Repair and Regeneration |
| US20130089594A1 (en) * | 2010-04-12 | 2013-04-11 | Converge Biotech Inc. | Macroporous bioengineered scaffolds for cell transplantation |
| US20110269231A1 (en) * | 2010-04-22 | 2011-11-03 | Wisconsin Alumni Research Foundation | Proteoglycan-binding peptides that modulate stem cell behavior |
| TWI415638B (zh) * | 2010-04-29 | 2013-11-21 | Nat Health Research Institutes | Composite material for repairing cartilage tissue and preparation method thereof |
| WO2011163669A2 (en) | 2010-06-25 | 2011-12-29 | President And Fellows Of Harvard College | Co-delivery of stimulatory and inhibitory factors to create temporally stable and spatially restricted zones |
| WO2012009341A2 (en) * | 2010-07-12 | 2012-01-19 | The Trustees Of Columbia University In The City Of New York | Tissue scaffolds for controlled release of active agents |
| US9938501B2 (en) | 2010-07-28 | 2018-04-10 | Jointechlabs, Inc. | Encapsulated adipose-derived stem cells, methods for preparation and theraputic use |
| SI2624873T1 (sl) * | 2010-10-06 | 2020-07-31 | President And Fellows Of Harvard College | Injektabilni, pore-formirajoči hidrogeli za celične terapije - na osnovi materialov |
| EP2630234B1 (en) * | 2010-10-18 | 2017-12-13 | Sunshine Biotech Inc. | Human multipotent embryonic stem cell-like progenitor cells |
| WO2012064697A2 (en) | 2010-11-08 | 2012-05-18 | President And Fellows Of Harvard College | Materials presenting notch signaling molecules to control cell behavior |
| WO2012148684A1 (en) * | 2011-04-27 | 2012-11-01 | President And Fellows Of Harvard College | Cell-friendly inverse opal hydrogels for cell encapsulation, drug and protein delivery, and functional nanoparticle encapsulation |
| ES2685327T3 (es) | 2011-04-28 | 2018-10-08 | President And Fellows Of Harvard College | Armazones tridimensionales macroscópicos preformados inyectables para administración mínimamente invasiva |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| EP4083074A1 (en) | 2011-06-02 | 2022-11-02 | Massachusetts Institute Of Technology | Modified alginates for cell encapsulation and cell therapy |
| WO2012167230A1 (en) | 2011-06-03 | 2012-12-06 | President And Fellows Of Harvard College | In situ antigen-generating cancer vaccine |
| US8753309B2 (en) | 2011-06-24 | 2014-06-17 | The Invention Science Fund I, Llc | Device, system, and method including micro-patterned cell treatment array |
| FR2979110B1 (fr) * | 2011-08-16 | 2013-09-27 | Etat Francais Ministere De La Defense Service De Sante Des Armees | Modelisation in vitro des niches medullaires a cellules souches hematopoietiques : un outil pour etudier la regulation de l'hematopoiese, evaluer le potentiel de nichage d'un greffon hematopoietique et tester la pharmaco-toxicologie de medicaments. |
| JP5876787B2 (ja) | 2011-08-31 | 2016-03-02 | 富士フイルム株式会社 | 細胞移植用細胞構造体および細胞移植用細胞集合体 |
| CA2848785A1 (en) | 2011-09-16 | 2013-03-21 | Ferring B.V. | A fast dissolving pharmaceutical composition |
| JP6018477B2 (ja) * | 2011-11-11 | 2016-11-02 | Hoya株式会社 | 人工骨−軟骨複合体及びその製造方法 |
| EP2802350B1 (en) * | 2012-01-13 | 2017-12-20 | President and Fellows of Harvard College | Controlled delivery of tlr agonists in structural polymeric devices |
| US9861663B2 (en) * | 2012-02-23 | 2018-01-09 | Technion Research & Development Foundation Ltd. | Ex-vivo vascularized implant composition comprising poly-l-lactic acid, polylactic-co-glycolic-acid and olfactory bulb cells |
| ES2773895T3 (es) | 2012-04-16 | 2020-07-15 | Harvard College | Composiciones de sílice mesoporosa para modular las respuestas inmunitarias |
| RU2014152445A (ru) * | 2012-07-12 | 2016-08-27 | Ферринг Б.В. | Композиции на основе диклофенака |
| US9884851B2 (en) | 2012-10-19 | 2018-02-06 | Massachusetts Institute Of Technology | Heterocycle-bisamide inhibitors of scavenger receptor BI |
| US11883246B2 (en) | 2012-11-21 | 2024-01-30 | Trustees Of Boston University | Tissue markers and uses thereof |
| WO2014110591A1 (en) * | 2013-01-14 | 2014-07-17 | Fred Hutchinson Cancer Research Center | Compositions and methods for delivery of immune cells to treat un-resectable or non-resected tumor cells and tumor relapse |
| EP2967833A4 (en) | 2013-03-14 | 2016-11-09 | Lifenet Health | FACED FIBER AND METHOD FOR USE THEREOF |
| WO2014165652A1 (en) * | 2013-04-03 | 2014-10-09 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Pem layer-by-layer systems for coating substrates to improve bioactivity and biomolecule delivery |
| US10016524B2 (en) * | 2013-04-11 | 2018-07-10 | President And Fellows Of Harvard College | Prefabricated alginate-drug bandages |
| EP2983643A4 (en) | 2013-04-12 | 2016-12-28 | Univ Columbia | PROCESS FOR HOST CELL HOMING AND TOOTH MARK GENERATION |
| WO2015077401A1 (en) | 2013-11-20 | 2015-05-28 | Drexel University | Compositions and methods for macrophage conversion |
| JP6787789B2 (ja) | 2014-04-04 | 2020-11-18 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 詰め替え可能な薬物送達デバイスおよびその使用方法 |
| EP3137105A4 (en) | 2014-04-30 | 2017-12-27 | President and Fellows of Harvard College | Combination vaccine devices and methods of killing cancer cells |
| WO2015192017A1 (en) * | 2014-06-12 | 2015-12-17 | President And Fellows Of Harvard College | Interpenetrating network hydrogels with independently tunable stiffness |
| JP6104312B2 (ja) * | 2014-06-19 | 2017-03-29 | 日東電工株式会社 | 組織再生促進剤 |
| KR102758574B1 (ko) * | 2014-07-17 | 2025-01-21 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 생물의학적 적용을 위한 제어가능한 자기-어닐링 마이크로겔 입자 |
| CN112999429B (zh) | 2014-08-01 | 2022-07-22 | 麻省理工学院 | 用于抗纤维化材料的修饰的藻酸盐以及应用 |
| MA41044A (fr) | 2014-10-08 | 2017-08-15 | Novartis Ag | Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer |
| CA2964367C (en) | 2014-10-14 | 2024-01-30 | Novartis Ag | Antibody molecules to pd-l1 and uses thereof |
| WO2016094108A1 (en) * | 2014-12-08 | 2016-06-16 | Cormatrix Cardiovascular, Inc. | Anisotropic constructs and methods for forming and using same for treating damaged biological tissue |
| HK1247861A1 (zh) | 2015-01-30 | 2018-10-05 | President And Fellows Of Harvard College | 用於癌症治疗的肿瘤周围和肿瘤内部材料 |
| WO2016160918A1 (en) * | 2015-03-31 | 2016-10-06 | The University Of North Carolina At Chapel Hill | Delivery vehicles for stem cells and uses thereof |
| TWI741980B (zh) | 2015-04-07 | 2021-10-11 | 大陸商四川藍光英諾生物科技股份有限公司 | 一種生物磚及其用途 |
| EP3903843A1 (en) * | 2015-04-07 | 2021-11-03 | Revotek Co., Ltd | Compositions for cell-based three dimensional printing |
| CN114099793A (zh) * | 2015-04-10 | 2022-03-01 | 哈佛学院院长等 | 免疫细胞捕获装置及其制备和使用方法 |
| US10537070B2 (en) | 2015-04-15 | 2020-01-21 | Ecovative Design Llc | Process for the production of mycelial composite surfaces in a roll-to-roll format |
| DE102015122375A1 (de) | 2015-05-29 | 2016-12-01 | Technische Universität Ilmenau | Nachbildung einer Stammzellnische eines Organismus sowie Verfahren zu deren Erzeugung |
| DK3317301T3 (da) | 2015-07-29 | 2021-06-28 | Immutep Sas | Kombinationsterapier omfattende antistofmolekyler mod lag-3 |
| EP4378957A3 (en) | 2015-07-29 | 2024-08-07 | Novartis AG | Combination therapies comprising antibody molecules to pd-1 |
| WO2017019897A1 (en) | 2015-07-29 | 2017-02-02 | Novartis Ag | Combination therapies comprising antibody molecules to tim-3 |
| JP6741408B2 (ja) * | 2015-09-11 | 2020-08-19 | 国立大学法人横浜国立大学 | 細胞包埋ビーズ及びその製造方法 |
| JP6675859B2 (ja) * | 2015-10-30 | 2020-04-08 | 国立大学法人横浜国立大学 | 血管網被包細胞包埋ビーズ及びその製造方法、並びに前記血管網被包細胞包埋ビーズを用いた集積体及びその製造方法 |
| JP6840751B2 (ja) | 2015-11-01 | 2021-03-10 | マサチューセッツ インスティテュート オブ テクノロジー | 改善された性質を有する材料 |
| WO2017075631A1 (en) | 2015-11-01 | 2017-05-04 | Massachusetts Institute Of Technology | Modified alginates for anti-fibrotic materials and applications |
| KR102833068B1 (ko) | 2015-12-17 | 2025-07-14 | 노파르티스 아게 | Pd-1에 대한 항체 분자 및 그의 용도 |
| CN109069874A (zh) * | 2016-01-07 | 2018-12-21 | 密歇根大学董事会 | 用于在体内捕获转移性乳腺癌细胞的植入式支架 |
| EP3190176A1 (en) | 2016-01-11 | 2017-07-12 | IMBA-Institut für Molekulare Biotechnologie GmbH | Method for tissue culture development on scaffold and differentiated tissue culture |
| WO2017136837A1 (en) | 2016-02-06 | 2017-08-10 | President And Fellows Of Harvard College | Recapitulating the hematopoietic niche to reconstitute immunity |
| CN120478728A (zh) | 2016-02-12 | 2025-08-15 | 渥太华大学 | 植物和真菌的去细胞化细胞壁结构及其作为支架材料的用途 |
| JP6854530B2 (ja) * | 2016-02-16 | 2021-04-07 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 病原体ワクチンならびにその製造および使用方法 |
| EP3426319B1 (en) | 2016-03-07 | 2022-10-26 | The Regents of The University of California | Bioartificial ultrafiltration device and methods related thereto |
| EP3468633A1 (en) | 2016-06-13 | 2019-04-17 | Massachusetts Institute Of Technology | Surface-coated continuous glucose monitors |
| AU2017283480A1 (en) | 2016-06-13 | 2019-01-24 | Torque Therapeutics, Inc. | Methods and compositions for promoting immune cell function |
| CN109415695A (zh) * | 2016-06-17 | 2019-03-01 | 国立大学法人横浜国立大学 | 毛发再生用细胞包埋珠及其制备方法以及毛发再生用试剂盒 |
| EP4606890A3 (en) | 2016-07-13 | 2025-12-03 | President and Fellows of Harvard College | Antigen-presenting cell-mimetic scaffolds and methods for making and using the same |
| KR102638898B1 (ko) | 2016-08-02 | 2024-02-22 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 면역 반응을 조정하기 위한 생체재료 |
| FR3055805B1 (fr) * | 2016-09-09 | 2020-05-15 | Assistance Publique - Hopitaux De Paris (Ap-Hp) | Biomateriau a usage therapeutique |
| US11150251B2 (en) | 2016-10-07 | 2021-10-19 | Clemson University Research Foundation | Bi-functional arginine-glycine-aspartic acid (RGD) peptides and methods to promote angiogenesis |
| US20190376016A1 (en) * | 2016-11-22 | 2019-12-12 | Nutech Ventures | Personalized cellular biomanufacturing with a closed, miniature cell culture system |
| JP2020515544A (ja) * | 2017-03-25 | 2020-05-28 | ユニバーシティ オブ マイアミ | 治療細胞を含む生物学的足場 |
| EP3624730A4 (en) | 2017-05-16 | 2021-04-14 | Embody Inc. | COMPOSITIONS OF BIOPOLYMERS, SCAFFOLDING AND DEVICES |
| CN110214033A (zh) * | 2017-05-17 | 2019-09-06 | 先进美学科技公司 | 类琼脂结构及相关的使用和制备方法 |
| EP3409303A1 (en) * | 2017-06-02 | 2018-12-05 | Geistlich Pharma AG | Use of a resorbable crosslinked form stable composition for preparing a membrane |
| WO2018227205A1 (en) * | 2017-06-09 | 2018-12-13 | President And Fellows Of Harvard College | Compositions for inducing an immune response |
| JP7539832B2 (ja) | 2017-06-12 | 2024-08-26 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 細胞生着のためのパッチグラフト組成物 |
| WO2019018727A1 (en) | 2017-07-21 | 2019-01-24 | Washington University | METHODS AND COMPOSITIONS FOR T-CELL ACTIVATION |
| KR20210032924A (ko) | 2017-09-05 | 2021-03-25 | 토크 테라퓨틱스, 인코포레이티드 | 치료용 단백질 조성물 및 그의 제조 및 사용 방법 |
| EP3691686B1 (en) | 2017-10-06 | 2024-12-18 | The Regents Of The University Of Michigan | Detection of metastatic disease and related methods |
| CA3116829A1 (en) * | 2017-10-17 | 2019-04-25 | The Methodist Hospital System | Delivery devices |
| WO2019084209A1 (en) | 2017-10-24 | 2019-05-02 | Embody Llc | BIOPOLYMER SCAFFOLDING IMPLANTS AND METHODS OF MAKING SAME |
| US11318231B2 (en) | 2017-11-06 | 2022-05-03 | Massachusetts Institute Of Technology | Anti-inflammatory coatings to improve biocompatibility of neurological implants |
| KR102820005B1 (ko) | 2018-02-02 | 2025-06-12 | 웨이크 포리스트 유니버시티 헬스 사이언시즈 | 면역요법 관련 오가노이드 및 그의 제조 및 사용 방법 |
| GB2573327B (en) * | 2018-05-03 | 2021-05-12 | Mosa Meat Bv | Apparatus and process for production of tissue from cells |
| WO2019215557A1 (en) * | 2018-05-07 | 2019-11-14 | Reelabs Pvt. Ltd. | The method of autologous primary hair follicles preparation in 3d culture |
| US12221621B2 (en) | 2018-06-04 | 2025-02-11 | Ramot At Tel-Aviv University Ltd. | Support medium for 3D printing of biomaterials |
| WO2020023462A1 (en) * | 2018-07-23 | 2020-01-30 | Georgia Tech Research Corporation | Synthetic hydrogel carriers for muscle repair |
| WO2020061129A1 (en) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions and methods for labeling and modulation of cells in vitro and in vivo |
| JP7269594B2 (ja) * | 2018-09-27 | 2023-05-09 | 株式会社村田製作所 | 細胞分離フィルター及び細胞分離方法 |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| EP3866835B1 (en) * | 2018-10-19 | 2024-01-03 | The Regents Of The University Of Michigan | Method for monitoring autoimmune disease |
| BR112021009655A2 (pt) * | 2018-11-20 | 2021-11-09 | Ecovative Design Llc | Métodos de gerar estruturas miceliais e aplicações das mesmas |
| JP2022514568A (ja) * | 2018-12-17 | 2022-02-14 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 免疫系のモジュレーションのための生物工学的スキャフォールドおよびその使用 |
| CA3128219A1 (en) | 2019-02-01 | 2020-08-06 | Michael P. FRANCIS | Microfluidic extrusion |
| EP3930687A4 (en) | 2019-02-25 | 2023-06-07 | The University of Chicago | METHODS AND COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE CONDITIONS USING ECM AFFINITY PEPTIDES LINKED TO ANTI-INFLAMMATORY AGENTS |
| JPWO2020230885A1 (pl) * | 2019-05-15 | 2020-11-19 | ||
| EP4034148A4 (en) | 2019-09-23 | 2025-09-10 | Harvard College | BIOMATERIAL-BASED ANTIGEN-FREE VACCINE AND ITS USE |
| US20240082053A1 (en) * | 2019-10-18 | 2024-03-14 | Carnegie Mellon University | Monolayer cell patch in an extracellular matrix scaffold |
| WO2021207724A2 (en) * | 2020-04-10 | 2021-10-14 | North Carolina State University | Enhanced viral transduction of mammalian cells using material scaffolds |
| CN112089883B (zh) * | 2020-09-14 | 2022-01-04 | 海南希睿达生物技术有限公司 | 一种医用冷敷敷料及其制备方法 |
| KR102348467B1 (ko) * | 2021-07-14 | 2022-01-07 | 주식회사 휴메딕스 | Dna 분획물을 포함하는 필러 제조방법 및 이로부터 제조된 필러 |
| WO2023147291A2 (en) * | 2022-01-25 | 2023-08-03 | The Board Of Trustees Of The Leland Stanford Junior University | Gene editing and delivery of myeloid cells to promote wound healing |
| WO2023158629A1 (en) * | 2022-02-15 | 2023-08-24 | The Regents Of The University Of Michigan | Platform for monitoring transplant rejection |
Family Cites Families (247)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US5073627A (en) | 1989-08-22 | 1991-12-17 | Immunex Corporation | Fusion proteins comprising GM-CSF and IL-3 |
| GB9206504D0 (en) * | 1992-03-25 | 1992-05-06 | Jevco Ltd | Heteromorphic sponges as wound implants |
| CA2178902A1 (en) | 1993-12-14 | 1995-06-22 | Drew Pardoll | Controlled release of pharmaceutically active substances for immunotherapy |
| US5538733A (en) | 1994-07-07 | 1996-07-23 | Willmar Poultry Company, Inc. | Method of priming an immune response in a one-day old animal |
| US6429199B1 (en) | 1994-07-15 | 2002-08-06 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules for activating dendritic cells |
| ATE420171T1 (de) | 1994-07-15 | 2009-01-15 | Univ Iowa Res Found | Immunomodulatorische oligonukleotide |
| US5625048A (en) | 1994-11-10 | 1997-04-29 | The Regents Of The University Of California | Modified green fluorescent proteins |
| US6251396B1 (en) | 1994-11-18 | 2001-06-26 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein |
| US6329499B1 (en) | 1994-11-18 | 2001-12-11 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein |
| CA2249354A1 (en) | 1996-03-28 | 1997-10-02 | Genitrix, L.L.C. | Opsonin-enhanced cells, and methods of modulating an immune response to an antigen |
| IL118376A0 (en) | 1996-05-22 | 1996-09-12 | Univ Ben Gurion | Polysaccharide sponges for cell culture and transplantation |
| AU3214797A (en) | 1996-05-28 | 1998-01-05 | Regents Of The University Of Michigan, The | Engineering oral tissues |
| US6124128A (en) | 1996-08-16 | 2000-09-26 | The Regents Of The University Of California | Long wavelength engineered fluorescent proteins |
| JP4335316B2 (ja) | 1996-09-19 | 2009-09-30 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン | アルギネートまたは修飾アルギネートのようなポリサッカライドを含むポリマー |
| US5863551A (en) | 1996-10-16 | 1999-01-26 | Organogel Canada Ltee | Implantable polymer hydrogel for therapeutic uses |
| GB2318577B (en) | 1996-10-28 | 2000-02-02 | Johnson & Johnson Medical | Solvent dried polysaccharide sponges |
| GB2323282B (en) | 1997-03-17 | 2001-03-07 | Bristol Myers Squibb Co | Improvements relating to hygiene and medical products |
| JP4085341B2 (ja) | 1997-03-31 | 2008-05-14 | ザ、リージエンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン | 開いたポアの生分解性マトリックス |
| JP4132089B2 (ja) | 1997-05-30 | 2008-08-13 | オステオバイオロジックス,インコーポレイテッド | 繊維強化多孔性生体分解性移植デバイス |
| DE69836428T2 (de) | 1997-08-21 | 2007-09-27 | Takara Bio Inc., Otsu | Karzinostatische wirkstoffe |
| US6160084A (en) | 1998-02-23 | 2000-12-12 | Massachusetts Institute Of Technology | Biodegradable shape memory polymers |
| CA2322435A1 (en) | 1998-03-02 | 1999-09-10 | Applied Vaccine Technologies Corp. | Methods and devices for modulating the immune response |
| ATE356630T1 (de) | 1998-04-03 | 2007-04-15 | Univ Iowa Res Found | Verfahren und produkte zur stimulierung des immunsystems mittels immunotherapeutischer oligonukleotide und zytokine |
| JP2002511284A (ja) | 1998-04-09 | 2002-04-16 | シャーロット−メクレンバーグ・ホスピタル・オーソリティ | 三次元組織の創造 |
| US7427602B1 (en) | 1998-05-13 | 2008-09-23 | The Regents Of The University Of Michigan | Sustained DNA delivery from structural matrices |
| US7244714B1 (en) | 1998-06-12 | 2007-07-17 | Aradigm Corporation | Methods of delivering aerosolized polynucleotides to the respiratory tract |
| FR2780730B1 (fr) | 1998-07-01 | 2000-10-13 | Corneal Ind | Compositions biphasiques injectables, notamment utiles en chirurgies reparatrice et esthetique |
| DE69924615T3 (de) | 1998-07-30 | 2011-05-05 | The Government Of The United States Of America, Represented By The Department Of Health & Human Services, National Institute Of Health, Office Of Technology Transfer | Thymosin beta 4 stimuliert wundheilung |
| EP1374908A3 (en) | 1998-10-09 | 2004-03-24 | The Regents Of The University Of Michigan | Polymer-drug conjugates comprising hydrazide linkers |
| CZ301212B6 (cs) | 1998-10-16 | 2009-12-09 | Smithkline Beecham Biologicals S. A. | Vakcinacní prostredek |
| US7109003B2 (en) | 1998-12-23 | 2006-09-19 | Abgenix, Inc. | Methods for expressing and recovering human monoclonal antibodies to CTLA-4 |
| US6974698B1 (en) | 1999-01-15 | 2005-12-13 | The United States Of America As Represented By The Department Of Health And Human Services | Methods for delivering biologically active molecules into cells |
| CA2689696C (en) | 1999-02-26 | 2013-08-06 | Novartis Vaccines And Diagnostics, Inc. | Microemulsions with adsorbed macromolecules and microparticles |
| WO2000056375A2 (en) | 1999-03-19 | 2000-09-28 | The Regents Of The University Of Michigan | Mineralization and cellular patterning on biomaterial surfaces |
| US6767928B1 (en) | 1999-03-19 | 2004-07-27 | The Regents Of The University Of Michigan | Mineralization and biological modification of biomaterial surfaces |
| PT1163019E (pt) | 1999-03-25 | 2007-12-06 | Metabolix Inc | Dispositivos médicos e aplicações de polímeros de poli-hidroxialcanoato |
| JP2002542326A (ja) | 1999-04-09 | 2002-12-10 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン | 多孔性ハイドロゲル製品の製造 |
| US6306424B1 (en) | 1999-06-30 | 2001-10-23 | Ethicon, Inc. | Foam composite for the repair or regeneration of tissue |
| AU782297B2 (en) * | 1999-06-30 | 2005-07-14 | Ethicon Inc. | Porous tissue scaffoldings for the repair or regeneration of tissue |
| US8084258B2 (en) | 1999-07-12 | 2011-12-27 | University Of Basel | Manipulation of tissue of organ type using the notch pathway |
| CN1378445B (zh) * | 1999-08-06 | 2013-02-06 | 得克萨斯系统大学评议会 | 药物释放生物可降解纤维植入物 |
| US7015205B1 (en) | 1999-10-18 | 2006-03-21 | St. Vincent's Hospital And Medical Center Of New York | Melanoma vaccine and methods of making and using same |
| AU1622801A (en) | 1999-11-18 | 2001-05-30 | Regents Of The University Of Michigan, The | Sustained drug delivery from structural matrices |
| US6682754B2 (en) | 1999-11-24 | 2004-01-27 | Willmar Poultry Company, Inc. | Ovo delivery of an immunogen containing implant |
| US6790840B1 (en) | 1999-11-26 | 2004-09-14 | The Regents Of The University Of Michigan | Reversibly cross-linked hydrogels |
| US20020098167A1 (en) | 2000-07-31 | 2002-07-25 | Piero Anversa | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| JP2004507237A (ja) * | 2000-08-21 | 2004-03-11 | ライスユニバーシティ | マトリクスタンパク質の産生を促進する組織工学足場 |
| WO2002020825A1 (en) | 2000-09-09 | 2002-03-14 | The Research Foundation Of State University Of New York | Method and compositions for isolating metastatic cancer cells, and use in measuring metastatic potential of a cancer thereof |
| US6748954B2 (en) | 2000-10-27 | 2004-06-15 | The Regents Of The University Of Michigan | Drug release from polymer matrices through mechanical stimulation |
| AU2002212739A1 (en) * | 2000-11-14 | 2002-05-27 | Osteogenesis Co., Ltd. | Compositions for forming bone or periodontium and injections for forming bone orperiodontium |
| AU2002218154A1 (en) | 2000-11-27 | 2002-06-03 | Jens Christian Jensenius | Collectins as adjuvants |
| US20070198739A1 (en) | 2001-01-19 | 2007-08-23 | Streamworks Technologies, Inc. | System and method for routing media |
| CA2434320A1 (en) | 2001-01-24 | 2002-08-01 | Schering Corporation | Chemokines as adjuvants of immune response |
| US7029697B2 (en) | 2001-02-14 | 2006-04-18 | Northwestern University | Controlled surface-associated delivery of genes and oligonucleotides |
| EP1372418A4 (en) | 2001-02-26 | 2006-01-25 | Univ | NON-OLIGOMERIZING TANDEM FLUORESCENT PROTEINS |
| JP2002263981A (ja) | 2001-03-14 | 2002-09-17 | Murata Mach Ltd | 板材吸着持ち上げ装置の吸着制御装置 |
| US20020131953A1 (en) | 2001-03-14 | 2002-09-19 | Ut Southwestern Medical Center | In situ langerhans cell vaccine |
| US6656488B2 (en) | 2001-04-11 | 2003-12-02 | Ethicon Endo-Surgery, Inc. | Bioabsorbable bag containing bioabsorbable materials of different bioabsorption rates for tissue engineering |
| US20030082806A1 (en) * | 2001-04-27 | 2003-05-01 | Xcyte Therapies, Inc. | Maturation of antigen-presenting cells using activated T cells |
| WO2002092054A2 (en) | 2001-05-11 | 2002-11-21 | Ortho-Mcneil Pharmaceutical, Inc. | Immune modulation device for use in animals |
| US20030118630A1 (en) | 2001-12-07 | 2003-06-26 | Anthony Cerami | Immune modulation device for use in animals |
| JP2004535425A (ja) | 2001-06-13 | 2004-11-25 | マサチューセッツ インスティチュート オブ テクノロジー | invivoバイオリアクタ |
| US7297343B2 (en) * | 2001-07-31 | 2007-11-20 | Biosurface Engineering Technologies, Inc. | Bioactive medical films |
| US7354909B2 (en) | 2001-08-14 | 2008-04-08 | The United States Of America As Represented By Secretary Of The Department Of Health And Human Services | Method for rapid generation of mature dendritic cells |
| CA2412012C (en) * | 2001-11-20 | 2011-08-02 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage |
| MXPA04006438A (es) | 2001-12-31 | 2005-06-08 | Ares Lab Llc | Composiciones hemostaticas y metodos para el control de sangrado. |
| US7575759B2 (en) | 2002-01-02 | 2009-08-18 | The Regents Of The University Of Michigan | Tissue engineering scaffolds |
| WO2003070291A1 (en) | 2002-02-19 | 2003-08-28 | National Institute Of Advanced Industrial Science And Technology | Implant containing cells having growhfactor gene transferred thereinto |
| US20070026518A1 (en) | 2005-03-29 | 2007-02-01 | The Regents Of The University Of California | Controlling stem cell destiny with tunable matrices |
| US20080233181A1 (en) | 2002-04-12 | 2008-09-25 | Nagy Jon O | Nanoparticle adjuvants for sub-unit vaccines |
| US6811777B2 (en) | 2002-04-13 | 2004-11-02 | Allan Mishra | Compositions and minimally invasive methods for treating incomplete connective tissue repair |
| WO2003089506A1 (en) | 2002-04-22 | 2003-10-30 | Purdue Research Foundation | Hydrogels having enhanced elasticity and mechanical strength properties |
| MXPA04010415A (es) | 2002-04-22 | 2005-02-17 | Bioniche Life Sciences Inc | Composiciones oligonucleotdias y su uso para la modulacion de respuestas inmunes. |
| US20040242469A1 (en) | 2002-05-13 | 2004-12-02 | Lee Richard T. | Angiogenesis and cardiac tissue engineering with peptide hydrogels and related compositions and methods of use thereof |
| AUPS312602A0 (en) | 2002-06-21 | 2002-07-18 | James Cook University | Organ arrest, protection, preservation and recovery |
| US7332160B2 (en) | 2002-07-12 | 2008-02-19 | Boston Scientific Scimed, Inc. | Medical device and method for tissue removal and repair |
| CN103073620B (zh) | 2002-09-12 | 2014-12-10 | 肿瘤疗法科学股份有限公司 | Kdr肽和包括该肽的疫苗 |
| US20040136968A1 (en) * | 2002-09-27 | 2004-07-15 | Verigen Ag | Autologous cells on a support matrix for tissue repair |
| US20040063206A1 (en) * | 2002-09-30 | 2004-04-01 | Rowley Jon A. | Programmable scaffold and method for making and using the same |
| AU2003272805A1 (en) * | 2002-10-01 | 2004-04-23 | Peter K. Law | Bioactive implants |
| JP2004159849A (ja) | 2002-11-12 | 2004-06-10 | National Institute Of Advanced Industrial & Technology | 細胞接着性生体吸収材料、人工血管およびそれらの製造方法 |
| CN1753912B (zh) | 2002-12-23 | 2011-11-02 | 惠氏公司 | 抗pd-1抗体及其用途 |
| US8940292B2 (en) | 2003-01-28 | 2015-01-27 | Wake Forest University Health Sciences | Enhancement of angiogenesis to grafts using cells engineered to produce growth factors |
| SE0301109D0 (sv) | 2003-04-14 | 2003-04-14 | Mallen Huang | Nucleotide vaccine composition |
| JP2006525405A (ja) | 2003-05-05 | 2006-11-09 | ベン‐グリオン ユニバーシティ オブ ザ ネゲヴ リサーチ アンド デベロップメント オーソリティ | 注入可能な架橋されたポリマー調製物およびその使用 |
| EP1475434A1 (en) | 2003-05-09 | 2004-11-10 | Oncoscience AG | Method for storing tumor cells |
| AU2004263094A1 (en) | 2003-07-09 | 2005-02-17 | Vaxdesign Corporation | Programmed immune responses using a vaccination node |
| US20060264380A1 (en) | 2003-07-21 | 2006-11-23 | Mats Hellstrom | Compounds and Methods for Promoting Angiogenesis |
| WO2005026318A2 (en) | 2003-07-31 | 2005-03-24 | Endacea, Inc. | Methods and compositions for producing antigenic responses |
| GB0317999D0 (en) | 2003-07-31 | 2003-09-03 | Univ Liege | Improvements in or relating to drug delivery systems |
| DE602004018163D1 (de) | 2003-08-29 | 2009-01-15 | Mayo Foundation | Hydrogel-porenbildner zur herstellung von biologisch abbaubaren gerüsten |
| JP5097400B2 (ja) * | 2003-09-03 | 2012-12-12 | デンドリセラピューティクス、インク. | 複合ワクチン |
| GB0321615D0 (en) | 2003-09-15 | 2003-10-15 | Glaxo Group Ltd | Improvements in vaccination |
| JP5021309B2 (ja) | 2003-10-16 | 2012-09-05 | ステファン ジョン ラルフ | 免疫調節性組成物およびその使用方法 |
| WO2005046461A1 (en) | 2003-11-07 | 2005-05-26 | Carnegie Mellon University | Robot for minimally invasive interventions |
| CA2448995A1 (en) | 2003-11-12 | 2005-05-12 | James Keenan | Device and method for attracting diseased cells and foreign substances |
| JP2005160669A (ja) * | 2003-12-02 | 2005-06-23 | Olympus Corp | 生体組織補填体の製造方法 |
| JP2005170816A (ja) * | 2003-12-09 | 2005-06-30 | Naoki Ishiguro | 軟骨修復用材料、およびその製造方法 |
| JP2005168760A (ja) | 2003-12-10 | 2005-06-30 | Gunze Ltd | 再生医療用支持体、血管再生用支持体、神経再生用支持体及び治療方法 |
| WO2005072088A2 (en) | 2003-12-11 | 2005-08-11 | Sciperio, Inc. | Immunotherapy compositions, method of making and method of use thereof |
| US11395865B2 (en) | 2004-02-09 | 2022-07-26 | DePuy Synthes Products, Inc. | Scaffolds with viable tissue |
| US7192693B2 (en) | 2004-02-24 | 2007-03-20 | University Of Washington | Methods for photopatterning hydrogels |
| EP1729781B1 (en) | 2004-03-15 | 2012-10-24 | Karaolis, David K. R. | A method for inhibiting cancer cell proliferation or increasing cancer cell apoptosis |
| CA2564512C (en) | 2004-04-28 | 2014-03-18 | Vaxdesign Corporation | Artificial immune system: methods for making and use |
| US20080113929A1 (en) | 2004-06-08 | 2008-05-15 | Coley Pharmaceutical Gmbh | Abasic Oligonucleotide as Carrier Platform for Antigen and Immunostimulatory Agonist and Antagonist |
| WO2007001332A2 (en) | 2004-08-04 | 2007-01-04 | University Of Massachusetts | Anti-pathogen immunoadhesins |
| EP1784493A2 (en) | 2004-09-01 | 2007-05-16 | The Government of the United States of America as Represented by The Department of Health and Human Services | Adenoviral vectors able to transduce apcs, potential use in immune response generation |
| CN101227913B (zh) | 2004-10-12 | 2013-08-14 | Fmc生物聚合物联合股份有限公司 | 自胶凝的藻酸盐体系及其用途 |
| US7235592B2 (en) | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
| US7999161B2 (en) | 2005-01-22 | 2011-08-16 | Alexander Oraevsky | Laser-activated nanothermolysis of cells |
| US7569850B2 (en) | 2005-01-24 | 2009-08-04 | Lawrence Livermore National Security, Llc | Lipid bilayers on nano-templates |
| WO2006102530A1 (en) | 2005-03-23 | 2006-09-28 | Mayo Foundation For Medical Education And Research | Photocrosslinkable oligo(poly (ethylene glycol) fumarate) hydrogels for cell and drug delivery |
| EP1712238A1 (en) | 2005-04-11 | 2006-10-18 | Institut Gustave Roussy | Anthracyclin induced immunogenic dead or dying cells composition |
| US8828433B2 (en) | 2005-04-19 | 2014-09-09 | Advanced Cardiovascular Systems, Inc. | Hydrogel bioscaffoldings and biomedical device coatings |
| US20070003595A1 (en) | 2005-04-19 | 2007-01-04 | Shaopeng Wang | Three dimensional micro-environments and methods of making and using same |
| CA2605749C (en) | 2005-04-26 | 2015-06-30 | Eisai Co., Ltd. | Compositions and methods for cancer immunotherapy |
| WO2006119619A1 (en) | 2005-05-06 | 2006-11-16 | Replicor Inc. | Oligonucleotides inhibiting cell proliferation |
| ITPI20050071A1 (it) | 2005-06-20 | 2006-12-21 | Giuseppe Calvosa | Composizione biocompatibile per la sostituzione/rigenerazione di tessuti |
| US7645742B2 (en) | 2005-06-22 | 2010-01-12 | Advocare International, L.P. | Composition for enhancing cellular energy |
| CN1302050C (zh) | 2005-07-07 | 2007-02-28 | 复旦大学 | 一种互穿网络聚合物超多孔水凝胶及其制备方法和应用 |
| WO2007022188A2 (en) | 2005-08-15 | 2007-02-22 | New York Society For The Relief Of The Ruptured And Crippled Maintaining The Hospital For Special Surgery | A porous non-biodegradable hydrogel admixed with a chemoattractant for tissue replacement |
| BRPI0503817A (pt) | 2005-09-12 | 2007-05-15 | Cristalia Prod Quimicos Farm | complexo imunogênico formado por antìgenos vacinais encapsulados por sìlica mesoporosa nanoestruturada |
| EP3184630B1 (en) | 2005-09-23 | 2019-07-17 | TiGenix, S.A.U. | Cell populations having immunoregulatory activity, method for isolation and uses |
| US20070081972A1 (en) | 2005-09-30 | 2007-04-12 | The University Of Iowa Research Foundation | Polymer-based delivery system for immunotherapy of cancer |
| EA200801045A1 (ru) | 2005-10-12 | 2008-10-30 | Кэнсер Рисерч Текнолоджи Лтд. | Способы и композиции для лечения иммунных нарушений |
| US8029575B2 (en) | 2005-10-25 | 2011-10-04 | Globus Medical, Inc. | Porous and nonporous materials for tissue grafting and repair |
| US20070116680A1 (en) | 2005-11-18 | 2007-05-24 | Rensselaer Polytechnic Institute | Stem cells within gel microenvironments |
| RU2420569C2 (ru) | 2005-11-29 | 2011-06-10 | Актогеникс Нв | Индукция толерантности к антигенам через слизистую |
| KR100687281B1 (ko) | 2005-11-30 | 2007-02-27 | 한국과학기술연구원 | 생리 활성 물질이 결합된 조직 재생용 주입형 온도 감응성플루로닉 유도체 하이드로겔 및 이의 제조 방법 |
| US8367628B2 (en) | 2005-12-01 | 2013-02-05 | Pronai Therapeutics, Inc. | Amphoteric liposome formulation |
| AU2015264807A1 (en) | 2005-12-13 | 2015-12-17 | President And Fellows Of Harvard College | Scaffolds for Cell Transplantation |
| WO2007070660A2 (en) | 2005-12-13 | 2007-06-21 | President And Fellows Of Harvard College | Scaffolds for cell transplantation |
| WO2007068489A2 (en) | 2005-12-14 | 2007-06-21 | Scil Technology Gmbh | A moldable biomaterial for bone regeneration |
| EP1806395A1 (en) | 2006-01-06 | 2007-07-11 | Stichting Sanquin Bloedvoorziening | Maturation of dendritic cells |
| US7615556B2 (en) | 2006-01-27 | 2009-11-10 | Bristol-Myers Squibb Company | Piperazinyl derivatives as modulators of chemokine receptor activity |
| US20070178159A1 (en) | 2006-01-30 | 2007-08-02 | Alza Corporation | In-Situ Forming Porous Scaffold |
| CA2676601A1 (en) | 2006-01-31 | 2007-08-09 | Medivas, Llc | Vaccine delivery compositions and methods of use |
| US20090041825A1 (en) | 2006-02-10 | 2009-02-12 | Kotov Nicholas A | Cell culture well-plates having inverted colloidal crystal scaffolds |
| US20070190646A1 (en) | 2006-02-10 | 2007-08-16 | The Trustees Of The University Of Pennsylvania | Regulating stem cell differentiation by controlling matrix elasticity |
| US20100015709A1 (en) | 2006-02-10 | 2010-01-21 | Trustees Of The University Of Pennsylvania | Regulating Stem Cell Differentiation By Controlling 2D and 3D Matrix Elasticity |
| JP2009528080A (ja) | 2006-02-27 | 2009-08-06 | エイジェンシー・フォー・サイエンス,テクノロジー・アンド・リサーチ | 硬化性骨セメント |
| US9456860B2 (en) | 2006-03-14 | 2016-10-04 | Kci Licensing, Inc. | Bioresorbable foaming tissue dressing |
| GB0605521D0 (en) | 2006-03-18 | 2006-04-26 | Isis Innovation | Adjuvant |
| US20090297579A1 (en) | 2006-06-01 | 2009-12-03 | Massachusetts Institute Of Technology | Control of Cells and Cell Multipotentiality in Three Dimensional Matrices |
| WO2007146319A2 (en) | 2006-06-13 | 2007-12-21 | Symphony Medical, Inc. | Methods and apparatus for using polymer-based beads and hydrogels for cardiac applications |
| US20070298067A1 (en) | 2006-06-22 | 2007-12-27 | Boston Scientific Scimed, Inc. | Control release drug coating for medical devices |
| US8318912B2 (en) | 2006-06-23 | 2012-11-27 | Augmenta Biologicals, Llc | Targeted immune conjugate comprising an antibody to glycophorin A and a M2e peptide |
| WO2008008266A2 (en) | 2006-07-07 | 2008-01-17 | University Of Pittsburgh- Of The Commonwealth System Of Higher Education | Biohybrid elastomeric scaffolds and methods of use thereof |
| JP4989934B2 (ja) | 2006-07-14 | 2012-08-01 | パナソニック株式会社 | スピーカシステム |
| US7993918B2 (en) | 2006-08-04 | 2011-08-09 | Anthrogenesis Corporation | Tumor suppression using placental stem cells |
| KR100802139B1 (ko) | 2006-08-08 | 2008-02-11 | 한국생명공학연구원 | 자성 나노입자를 함유하는 골드 나노케이지 |
| KR100818708B1 (ko) | 2006-08-18 | 2008-04-01 | 주식회사 하이닉스반도체 | 표면 세정을 포함하는 반도체소자 제조방법 |
| ITMI20061726A1 (it) | 2006-09-11 | 2008-03-12 | Fidia Farmaceutici | Derivati crosslinkati a base di acido ialuronico reticolato via click chemistry |
| CA2663722C (en) | 2006-09-21 | 2014-12-09 | Purdue Research Foundation | Collagen preparation and method of isolation |
| EP3590503A1 (en) | 2006-10-12 | 2020-01-08 | The University of Queensland | Compositions and methods for modulating immune responses |
| TWI362925B (en) | 2006-11-09 | 2012-05-01 | Kci Licensing Inc | Method for preparing a bioresorbable dressing comprising bioresorbable microparticles and method for preparing a bioresorbable dressing comprising bioresorbable microspheres |
| US8709464B2 (en) | 2007-01-10 | 2014-04-29 | The Regents Of The University Of Michigan | Porous objects having immobilized encapsulated biomolecules |
| WO2008109852A2 (en) | 2007-03-07 | 2008-09-12 | Uti Limited Partnership | Compositions and methods for the prevention and treatment of autoimmune conditions |
| JP2010522540A (ja) | 2007-03-21 | 2010-07-08 | アイディー バイオメディカル コーポレイション オブ ケベック | キメラ抗原 |
| US8501905B2 (en) | 2007-03-22 | 2013-08-06 | The Regents Of The University Of California | Synthetic cell platforms and methods of use thereof |
| EP1975230A1 (en) | 2007-03-30 | 2008-10-01 | Capsulution Nanoscience AG | Method for forming glucose sensing micro-particles, use of micro-particles, and kit |
| WO2008131074A1 (en) | 2007-04-19 | 2008-10-30 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Use of toll-like receptor-9 agonists, toll-like receptor-4 antagonists, and/or nuclear oligomerization domain-2 agonists for the treatment or prevention of toll-like receptor-4-associated disorders |
| US20100183602A1 (en) | 2007-06-05 | 2010-07-22 | Novartis Ag | Induction of Tolerogenic Phenotype in Mature Dendritic Cells |
| EP2167647A2 (en) | 2007-06-13 | 2010-03-31 | La Jolla Institute For Allergy And Immunology | Regulatory t cells and methods of making and using same |
| WO2009002401A2 (en) | 2007-06-21 | 2008-12-31 | President And Fellows Of Harvard College | Scaffolds for cell collection or elimination |
| ES2580161T3 (es) | 2007-06-29 | 2016-08-19 | Makoto Funaki | Sistemas de geles blandos en la modulación del desarrollo de células madre |
| CN102317303A (zh) | 2007-07-31 | 2012-01-11 | 约翰·霍普金斯大学 | 用于肿瘤或感染性疾病的免疫预防或免疫治疗的多肽-核酸偶联物 |
| GB0716264D0 (en) | 2007-08-21 | 2007-09-26 | Isis Innovation | Bilayers |
| US20090192079A1 (en) | 2007-10-09 | 2009-07-30 | Genzyme Corporation | Prolonged delivery of heparin-binding growth factors from heparin-derivatized collagen |
| KR100900837B1 (ko) | 2007-12-07 | 2009-06-04 | (주)두비엘 | 리포펩타이드와 폴리(i:c)를 아쥬반트로 포함하는 강력한백신 조성물 |
| EP2072617A1 (en) | 2007-12-12 | 2009-06-24 | Trimed Biotech GmbH | Method for producing dendritic cells |
| DE102008008522A1 (de) | 2008-02-11 | 2009-08-13 | Magforce Nanotechnologies Ag | Implantierbare Nanopartikel-enthaltende Produkte |
| WO2009102465A2 (en) | 2008-02-13 | 2009-08-20 | President And Fellows Of Harvard College | Continuous cell programming devices |
| US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
| WO2011063336A2 (en) | 2009-11-20 | 2011-05-26 | President And Fellows Of Harvard College | Secondary site of antigen stimulation for therapeutic vaccination |
| WO2009117721A1 (en) | 2008-03-21 | 2009-09-24 | 3D Biotek, Llc | Hybrid biomedical device fabricated from biomaterials and coated with a cell culture derived ecm coating |
| US9012399B2 (en) | 2008-05-30 | 2015-04-21 | President And Fellows Of Harvard College | Controlled release of growth factors and signaling molecules for promoting angiogenesis |
| WO2009155583A1 (en) | 2008-06-19 | 2009-12-23 | The Trustees Of The University Of Pennsylvania | Biomaterials for tissue replacement |
| NZ591130A (en) | 2008-08-25 | 2012-09-28 | Amplimmune Inc | Compositions comprising a PD-1 antagonists and cyclophosphamide and methods of use thereof |
| US8889124B2 (en) | 2008-09-25 | 2014-11-18 | The Board Of Trustees Of The Leland Stanford Junior University | Tolerogenic populations of dendritic cells |
| US8940331B2 (en) | 2008-11-22 | 2015-01-27 | The Board Of Trustees Of The Leland Stanford Junior University | Hydrogels, methods of making hydrogels, methods of using hydrogels, and methods of isolating, trapping, attracting, and/or killing cancer cells |
| KR101132732B1 (ko) | 2008-11-26 | 2012-04-06 | 한국과학기술연구원 | 인 시튜 조직재생용 지능형 다공성 생분해 고분자 지지체 및 이의 제조방법 |
| US8273373B2 (en) | 2008-12-30 | 2012-09-25 | Case Western Reserve University | Photocrosslinked biodegradable hydrogel |
| KR20110137290A (ko) | 2009-01-08 | 2011-12-22 | 알버트 아인슈타인 컬리지 오브 메디신 오브 예쉬바 유니버시티 | 세포벽 결합 세라미드 유사 당지질을 갖는 박테리아 백신 및 이의 용도 |
| JP2010227012A (ja) | 2009-03-27 | 2010-10-14 | Seiko Epson Corp | がん細胞捕捉デバイス |
| WO2010120749A2 (en) | 2009-04-13 | 2010-10-21 | President And Fellow Of Harvard College | Harnessing cell dynamics to engineer materials |
| US8551749B2 (en) | 2009-04-23 | 2013-10-08 | The Invention Science Fund I, Llc | Device including bone cage and method for treatment of disease in a subject |
| EP2461828B1 (en) | 2009-07-31 | 2017-06-21 | President and Fellows of Harvard College | Programming of cells for tolerogenic therapies |
| CN101655611B (zh) | 2009-09-11 | 2011-06-08 | 中国科学院长春应用化学研究所 | 一种具有双层杂化结构的反蛋白石水凝胶光子晶体的制备方法 |
| JP2013507123A (ja) | 2009-10-09 | 2013-03-04 | アナフォア インコーポレイテッド | C型レクチンドメインをベースとするコンビナトリアルライブラリー |
| CA2777162A1 (en) | 2009-10-09 | 2011-04-14 | Anaphore, Inc. | Polypeptides that bind il-23r |
| US20110207166A1 (en) | 2009-11-06 | 2011-08-25 | Sarah Rivkah Vaiselbuh | Human bone marrow microenvironments and uses thereof |
| WO2011074573A1 (ja) | 2009-12-18 | 2011-06-23 | 花王株式会社 | メソポーラスシリカ粒子の製造方法 |
| JP5603063B2 (ja) | 2009-12-21 | 2014-10-08 | 花王株式会社 | 複合シリカ粒子の製造方法 |
| ES2678143T3 (es) | 2010-01-19 | 2018-08-09 | President And Fellows Of Harvard College | Opsonina obtenida por ingeniería genética para la detección y el tratamiento de microorganismos patógenos |
| EP2538800B1 (en) | 2010-02-22 | 2017-08-09 | Le Labogroup SAS | Enclosing materials in natural transport systems |
| WO2011107822A1 (en) | 2010-03-02 | 2011-09-09 | King Abdullah University Of Science And Technology | High surface area fibrous silica nanoparticles |
| EP2543636B1 (en) | 2010-03-04 | 2025-08-06 | Tokyo Metropolitan Industrial Technology Research Institute | Process for producing porous silica, |
| WO2011109834A2 (en) | 2010-03-05 | 2011-09-09 | President And Fellows Of Harvard College | Enhancement of skeletal muscle stem cell engrafment by dual delivery of vegf and igf-1 |
| CN102905732A (zh) | 2010-03-15 | 2013-01-30 | 弗罗桑医疗设备公司 | 用于促进止血和/或伤口愈合的方法 |
| US20110256184A1 (en) | 2010-04-14 | 2011-10-20 | Battelle Memorial Institute | Non-ordered Mesoporous Silica Structure for Biomolecule Loading and Release |
| US20110300186A1 (en) | 2010-04-14 | 2011-12-08 | Battelle Memorial Institute | Functionalized Nano- and Micro-materials for Medical Therapies |
| EP2575773A4 (en) | 2010-05-26 | 2014-06-25 | Selecta Biosciences Inc | SYNTHETIC NANOTRÄGERKOMBINATIONSIMPFSTOFFE |
| GB201009273D0 (en) | 2010-06-03 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel vaccine |
| WO2011163669A2 (en) | 2010-06-25 | 2011-12-29 | President And Fellows Of Harvard College | Co-delivery of stimulatory and inhibitory factors to create temporally stable and spatially restricted zones |
| WO2012009611A2 (en) | 2010-07-16 | 2012-01-19 | The Johns Hopkins University | Methods and compositions for cancer immunotherapy |
| WO2012019049A1 (en) | 2010-08-04 | 2012-02-09 | Georgia Tech Research Corporation | Devices, systems, and methods for excavating cancer cells |
| SI2624873T1 (sl) | 2010-10-06 | 2020-07-31 | President And Fellows Of Harvard College | Injektabilni, pore-formirajoči hidrogeli za celične terapije - na osnovi materialov |
| WO2012064697A2 (en) | 2010-11-08 | 2012-05-18 | President And Fellows Of Harvard College | Materials presenting notch signaling molecules to control cell behavior |
| WO2012148684A1 (en) | 2011-04-27 | 2012-11-01 | President And Fellows Of Harvard College | Cell-friendly inverse opal hydrogels for cell encapsulation, drug and protein delivery, and functional nanoparticle encapsulation |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| ES2685327T3 (es) | 2011-04-28 | 2018-10-08 | President And Fellows Of Harvard College | Armazones tridimensionales macroscópicos preformados inyectables para administración mínimamente invasiva |
| EA201790045A1 (ru) | 2011-04-29 | 2017-09-29 | Селекта Байосайенсиз, Инк. | Наноносители, вырабатывающие имунную толерантность, для антиген-специфического удаления т-эффекторных клеток |
| WO2012167230A1 (en) | 2011-06-03 | 2012-12-06 | President And Fellows Of Harvard College | In situ antigen-generating cancer vaccine |
| BR112013033182A2 (pt) | 2011-06-24 | 2016-09-06 | Arqule Inc | compostos imidazopiridinil-aminopiridina substituída |
| SG10201608671SA (en) | 2011-07-18 | 2016-12-29 | Harvard College | Engineered Microbe-Targeting Molecules and Uses Thereof |
| US20130145488A1 (en) | 2011-12-06 | 2013-06-06 | Iowa State University Research Foundation, Inc. | Mesoporous silica nanoparticles suitable for co-delivery |
| EP2802350B1 (en) | 2012-01-13 | 2017-12-20 | President and Fellows of Harvard College | Controlled delivery of tlr agonists in structural polymeric devices |
| SG11201405552VA (en) | 2012-03-16 | 2014-10-30 | Merck Patent Gmbh | Targeting aminoacid lipids |
| ES2773895T3 (es) | 2012-04-16 | 2020-07-15 | Harvard College | Composiciones de sílice mesoporosa para modular las respuestas inmunitarias |
| KR102434075B1 (ko) | 2012-05-17 | 2022-08-19 | 익스텐드 바이오사이언시즈, 인크. | 개선된 약물 전달용 캐리어 |
| BR112014017645A2 (pt) | 2012-06-21 | 2017-06-27 | Compugen Ltd | molécula imunológica; polinucleotídeo; vetor; célula recombinante que compreende o vetor; método para produzir molécula imunológica; anticorpo ou fragmento de ligação de antígeno do mesmo; composição farmacêutica; uso da molécula imunológica, do anticorpo, do fragmento de ligação de anticorpo ou da composição farmacêutica; método diagnóstico para diagnosticar uma doença em um indivíduo, em que a doença é selecionada do grupo que consiste em câncer, uma doença autoimune ou uma doença infecciosa; ensaio para diagnosticar uma doença em uma amostra de tecido tomada de um indivíduo; uso de um anticorpo ou um fragmento que se liga especificamente à seq id no: 10; e método diagnóstico para determinar se realiza o uso ou administra a composição |
| US20140072510A1 (en) | 2012-09-13 | 2014-03-13 | Northwestern University | Synthetic Scaffolds for Metastasis Detection |
| US11413329B2 (en) | 2012-10-20 | 2022-08-16 | Board Of Regents, The University Of Texas System | Cancer cell trap |
| HK1214652A1 (zh) | 2013-03-13 | 2016-07-29 | 克里蒂科斯有限责任公司 | 用於检测胰腺癌的方法和组合物 |
| PT2996473T (pt) | 2013-05-18 | 2019-11-18 | Univ California | Composições e métodos para a ativação da sinalização dependente do ''estimulador de genes de interferão'' |
| JP6649250B2 (ja) | 2013-05-21 | 2020-02-19 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 操作されたヘム結合性構成物およびその使用 |
| US20160129053A1 (en) | 2013-05-24 | 2016-05-12 | President And Fellows Of Harvard College | Methods of isolating microorganisms and uses thereof |
| CA2987519A1 (en) | 2013-11-01 | 2015-05-07 | Yale University | Delivery vehicles |
| EP3125960B1 (en) | 2014-04-04 | 2020-06-03 | President and Fellows of Harvard College | Click-crosslinked hydrogels and methods of use |
| EP3137105A4 (en) | 2014-04-30 | 2017-12-27 | President and Fellows of Harvard College | Combination vaccine devices and methods of killing cancer cells |
| US11065362B2 (en) | 2014-06-12 | 2021-07-20 | President And Fellows Of Harvard College | Viscoelastic hydrogels with fast stress relaxation |
| US11229607B2 (en) | 2014-06-30 | 2022-01-25 | President And Fellows Of Harvard College | Hydrogel compositions comprising encapsulated cells and methods of use thereof |
| HK1247861A1 (zh) | 2015-01-30 | 2018-10-05 | President And Fellows Of Harvard College | 用於癌症治疗的肿瘤周围和肿瘤内部材料 |
| WO2016161372A1 (en) | 2015-04-01 | 2016-10-06 | President And Fellows Of Harvard College | Immunoconjugates for programming or reprogramming of cells |
| CN114099793A (zh) | 2015-04-10 | 2022-03-01 | 哈佛学院院长等 | 免疫细胞捕获装置及其制备和使用方法 |
| EP3331549B1 (en) | 2015-08-06 | 2020-12-23 | President and Fellows of Harvard College | Improved microbe-binding molecules and uses thereof |
| WO2017136837A1 (en) | 2016-02-06 | 2017-08-10 | President And Fellows Of Harvard College | Recapitulating the hematopoietic niche to reconstitute immunity |
| JP6854530B2 (ja) | 2016-02-16 | 2021-04-07 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 病原体ワクチンならびにその製造および使用方法 |
| EP4606890A3 (en) | 2016-07-13 | 2025-12-03 | President and Fellows of Harvard College | Antigen-presenting cell-mimetic scaffolds and methods for making and using the same |
| KR102638898B1 (ko) | 2016-08-02 | 2024-02-22 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 면역 반응을 조정하기 위한 생체재료 |
-
2006
- 2006-12-13 WO PCT/US2006/047823 patent/WO2007070660A2/en not_active Ceased
- 2006-12-13 AT AT06847667T patent/ATE534415T1/de active
- 2006-12-13 HU HUE10194565A patent/HUE051267T2/hu unknown
- 2006-12-13 EP EP06847667A patent/EP1960009B1/en active Active
- 2006-12-13 SI SI200632379T patent/SI2347775T1/sl unknown
- 2006-12-13 PT PT101945657T patent/PT2347775T/pt unknown
- 2006-12-13 AU AU2006326405A patent/AU2006326405B2/en active Active
- 2006-12-13 ES ES10194565T patent/ES2804472T3/es active Active
- 2006-12-13 PL PL10194565T patent/PL2347775T3/pl unknown
- 2006-12-13 US US11/638,796 patent/US8067237B2/en active Active
- 2006-12-13 EP EP10194626.7A patent/EP2347774B1/en active Active
- 2006-12-13 DK DK10194565.7T patent/DK2347775T3/da active
- 2006-12-13 JP JP2008545829A patent/JP5539649B2/ja active Active
- 2006-12-13 CA CA2632630A patent/CA2632630C/en active Active
- 2006-12-13 EP EP10194565.7A patent/EP2347775B1/en active Active
-
2011
- 2011-11-28 US US13/305,088 patent/US8932583B2/en active Active
-
2013
- 2013-11-13 JP JP2013234787A patent/JP5976622B2/ja not_active Expired - Fee Related
-
2014
- 2014-03-24 US US14/223,759 patent/US9132210B2/en active Active
-
2015
- 2015-06-25 US US14/750,423 patent/US9446107B2/en active Active
- 2015-07-14 JP JP2015140440A patent/JP6140222B2/ja active Active
-
2016
- 2016-03-30 US US15/085,858 patent/US20160271298A1/en not_active Abandoned
- 2016-04-21 US US15/135,213 patent/US10137184B2/en active Active
- 2016-04-21 US US15/135,207 patent/US10149897B2/en active Active
- 2016-12-26 JP JP2016250381A patent/JP6595446B2/ja active Active
-
2018
- 2018-10-25 US US16/170,313 patent/US11096997B2/en active Active
-
2019
- 2019-06-04 JP JP2019104265A patent/JP7065806B2/ja active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI2347775T1 (sl) | Ogrodja za celično transplantacijo | |
| WO2009002401A3 (en) | Scaffolds for cell collection or elimination | |
| IL178589A0 (en) | Polymer-based sustained release device | |
| WO2009076592A3 (en) | Medical devices having porous component for controlled diffusion | |
| IL186202A0 (en) | Device with engineered surface architecture coating for controlled drug release | |
| EP2077283A4 (en) | ETHYLENE COPOLYMER, COPOLYMER COMPOSITION, AND METHOD OF MANUFACTURE | |
| EP3185333A3 (en) | Organoselenium materials and their uses in organic light emitting devices | |
| WO2009048645A3 (en) | Lipid coatings for implantable medical devices | |
| HUE067052T2 (hu) | Szerves/szervetlen kompozit szeparátor porózus aktív bevonatréteggel és az azt tartalmazó elektrokémiai eszköz | |
| IL185782A0 (en) | Aqueous insecticidal compositions and the use thereof for protecting lignocellulose-containing materials | |
| WO2008024640A3 (en) | Biodegradable elastomeric scaffolds containing microintegrated cells | |
| EA200801542A1 (ru) | Полипропиленовые композиции | |
| ECSP109852A (es) | Uso de homo y copolímeros para la estabilización de formulaciones de principios activos | |
| GB2432838B (en) | Light emitting polymer composition and polymer light emitting device | |
| WO2008134475A3 (en) | Implant device release agents and methods of using same | |
| WO2007070792A3 (en) | Actuator handle for use with medical device deployment systems | |
| GB2437213B (en) | Polymer compound and polymer light emitting device using the same | |
| TWI346136B (en) | Conducting film composition for organic opto-electronic device comprising graft copolymer of self-doped conducting polymer and organic opto-electronic device using the same | |
| WO2007092043A3 (en) | Bioactive material delivery systems comprising sol-gel compositions | |
| EP2061326A4 (en) | COMPOSITION BASED ON BACILLUS SPP. AND CORRESPONDING SPECIES, AND THEIR USE IN PEST CONTROL | |
| WO2008104762A3 (en) | Bone-replacement materials, methods and devices | |
| TW200700085A (en) | Endoparasiticidal compositions | |
| WO2008022745A8 (de) | Formulierungen zur kontrollierten freisetzung agrochemischer wirkstoffe | |
| FR2910137B1 (fr) | Materiau electrolyte de dispositif electrocommandable, son procede de fabrication, dispositif electrocommandable le comprenant et procede de fabrication dudit dispositif | |
| ATE504623T1 (de) | Polypropylen-filme mit verbesserten optischen eigenschaften |