MX351975B - Composiciones y metodos para el tratamiento de infecciones y tumores. - Google Patents

Composiciones y metodos para el tratamiento de infecciones y tumores.

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Publication number
MX351975B
MX351975B MX2012007788A MX2012007788A MX351975B MX 351975 B MX351975 B MX 351975B MX 2012007788 A MX2012007788 A MX 2012007788A MX 2012007788 A MX2012007788 A MX 2012007788A MX 351975 B MX351975 B MX 351975B
Authority
MX
Mexico
Prior art keywords
antagonists
infections
tumors
subjects
treated
Prior art date
Application number
MX2012007788A
Other languages
English (en)
Inventor
Arlene Sharpe
Rama Amara
Gordon Freeman
Rafi Ahmed
Original Assignee
Emory Univ Star
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39484540&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX351975(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Emory Univ Star filed Critical Emory Univ Star
Publication of MX351975B publication Critical patent/MX351975B/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
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    • C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2740/10011—Retroviridae
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/10011—Arenaviridae
    • C12N2760/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
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    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

La presente invención se refiere a antagonistas de PD-1 que pueden utilizarse para reducir la expresión o actividad del PD-1 en un sujeto. Una respuesta inmunitaria específica para un agente infeccioso o las células tumorales puede mejorarse utilizando estos antagonistas de PD-1 en conjunto con un antígeno del agente infeccioso o el tumor. Así, los sujetos con infecciones, tales como infecciones persistentes, pueden tratarse utilizando antagonistas del PD-1. Además, los sujetos con tumores pueden tratarse utilizando los antagonistas del PD-1. En varios ejemplos, los sujetos pueden tratarse transplantando una cantidad terapéuticamente efectiva de linfocitos T activados, que reconocen un antígeno de interés y administrando una cantidad terapéuticamente efectiva de un antagonista de PD-1.
MX2012007788A 2006-12-27 2007-12-26 Composiciones y metodos para el tratamiento de infecciones y tumores. MX351975B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87751806P 2006-12-27 2006-12-27
PCT/US2007/088851 WO2008083174A2 (en) 2006-12-27 2007-12-26 Compositions and methods for the treatment of infections and tumors

Publications (1)

Publication Number Publication Date
MX351975B true MX351975B (es) 2017-11-06

Family

ID=39484540

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2012007788A MX351975B (es) 2006-12-27 2007-12-26 Composiciones y metodos para el tratamiento de infecciones y tumores.
MX2009006786A MX2009006786A (es) 2006-12-27 2007-12-26 Composiciones y metodos para el tratamiento de infecciones y tumores.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2009006786A MX2009006786A (es) 2006-12-27 2007-12-26 Composiciones y metodos para el tratamiento de infecciones y tumores.

Country Status (18)

Country Link
US (5) US20100040614A1 (es)
EP (4) EP2079760B1 (es)
JP (4) JP5623747B2 (es)
KR (1) KR101523391B1 (es)
CN (3) CN101663323A (es)
AU (1) AU2007339897B2 (es)
BR (1) BRPI0720724A2 (es)
CA (3) CA3045637A1 (es)
HK (1) HK1134679A1 (es)
HU (1) HUE030139T2 (es)
IL (4) IL199517A (es)
MX (2) MX351975B (es)
NZ (9) NZ594510A (es)
RU (2) RU2540490C2 (es)
SG (1) SG183663A1 (es)
SI (1) SI2079760T1 (es)
WO (1) WO2008083174A2 (es)
ZA (1) ZA200904492B (es)

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US7432351B1 (en) 2002-10-04 2008-10-07 Mayo Foundation For Medical Education And Research B7-H1 variants
DE10347710B4 (de) 2003-10-14 2006-03-30 Johannes-Gutenberg-Universität Mainz Rekombinante Impfstoffe und deren Verwendung
MX2007004176A (es) 2004-10-06 2007-06-15 Mayo Foundation B7-h1 y metodos de diagnosis, prognosis, y tratamiento de cancer.
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KR102097887B1 (ko) * 2008-09-26 2020-04-06 다나-파버 캔서 인스티튜트 인크. 인간 항-ｐｄ-１, ｐｄ-ｌ１, 및 ｐｄ-ｌ2 항체 및 그의 용도
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