CN106687483B - 使用人源化抗-bcma嵌合抗原受体治疗癌症 - Google Patents

使用人源化抗-bcma嵌合抗原受体治疗癌症 Download PDF

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CN106687483B
CN106687483B CN201580047918.4A CN201580047918A CN106687483B CN 106687483 B CN106687483 B CN 106687483B CN 201580047918 A CN201580047918 A CN 201580047918A CN 106687483 B CN106687483 B CN 106687483B
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seq
amino acid
acid sequence
bcma
cdr2
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CN106687483A (zh
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J·布罗格顿
E·崔
H·艾伯斯巴赫
D·格拉斯
H·于埃
C·H·琼
J·曼尼克
M·C·米伦
L·墨菲
G·普莱萨
C·理查森
M·鲁艾拉
R·辛格
王永强
吴期隆
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Novartis AG
University of Pennsylvania Penn
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University of Pennsylvania Penn
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    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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CN201580047918.4A 2014-07-21 2015-07-21 使用人源化抗-bcma嵌合抗原受体治疗癌症 Active CN106687483B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN2014082586 2014-07-21
CNPCT/CN2014/082586 2014-07-21
CNPCT/CN2014/090501 2014-11-06
CN2014090501 2014-11-06
PCT/US2015/041378 WO2016014565A2 (en) 2014-07-21 2015-07-21 Treatment of cancer using humanized anti-bcma chimeric antigen receptor

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CN106687483B true CN106687483B (zh) 2020-12-04

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US (3) US10174095B2 (enrdf_load_stackoverflow)
EP (1) EP3172237A2 (enrdf_load_stackoverflow)
JP (2) JP7054622B2 (enrdf_load_stackoverflow)
KR (1) KR102612313B1 (enrdf_load_stackoverflow)
CN (1) CN106687483B (enrdf_load_stackoverflow)
AU (2) AU2015292744C1 (enrdf_load_stackoverflow)
BR (1) BR112017001183A2 (enrdf_load_stackoverflow)
CA (1) CA2955386A1 (enrdf_load_stackoverflow)
CO (1) CO2017000507A2 (enrdf_load_stackoverflow)
IL (1) IL250043B (enrdf_load_stackoverflow)
MX (1) MX2017001011A (enrdf_load_stackoverflow)
MY (1) MY181834A (enrdf_load_stackoverflow)
RU (1) RU2751660C2 (enrdf_load_stackoverflow)
SG (1) SG11201700476VA (enrdf_load_stackoverflow)
TW (1) TWI750110B (enrdf_load_stackoverflow)
WO (1) WO2016014565A2 (enrdf_load_stackoverflow)

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