EA201891992A1 - Химерные рецепторы и способы их применения - Google Patents

Химерные рецепторы и способы их применения

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Publication number
EA201891992A1
EA201891992A1 EA201891992A EA201891992A EA201891992A1 EA 201891992 A1 EA201891992 A1 EA 201891992A1 EA 201891992 A EA201891992 A EA 201891992A EA 201891992 A EA201891992 A EA 201891992A EA 201891992 A1 EA201891992 A1 EA 201891992A1
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EA
Eurasian Patent Office
Prior art keywords
chimeric receptors
ways
application
immune cells
binding molecules
Prior art date
Application number
EA201891992A
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English (en)
Inventor
Джед Вилтзиус
Рубен Альварес Родригес
Элис Баккер
Тара Арведсон
Лоурен Ву
Original Assignee
Кайт Фарма, Инк.
Амген Инк.
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Publication date
Application filed by Кайт Фарма, Инк., Амген Инк. filed Critical Кайт Фарма, Инк.
Publication of EA201891992A1 publication Critical patent/EA201891992A1/ru

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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C07K2319/00—Fusion polypeptide
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    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Abstract

Согласно настоящему изобретению предложены антигенсвязывающие молекулы, химерные рецепторы и сконструированные иммунные клетки. Изобретение также относится к векторам, композициям и способам лечения и/или детектирования с применением антигенсвязывающих молекул и сконструированных иммунных клеток.
EA201891992A 2016-04-01 2017-03-31 Химерные рецепторы и способы их применения EA201891992A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662317068P 2016-04-01 2016-04-01
PCT/US2017/025573 WO2017173384A1 (en) 2016-04-01 2017-03-31 Chimeric receptors and methods of use thereof

Publications (1)

Publication Number Publication Date
EA201891992A1 true EA201891992A1 (ru) 2019-08-30

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EA201891992A EA201891992A1 (ru) 2016-04-01 2017-03-31 Химерные рецепторы и способы их применения

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US (3) US10597456B2 (ru)
EP (2) EP4180449A1 (ru)
JP (3) JP2019513370A (ru)
KR (5) KR20230165383A (ru)
CN (2) CN109641008B (ru)
AR (1) AR108066A1 (ru)
AU (3) AU2017240788B2 (ru)
BR (1) BR112018070260A2 (ru)
CA (2) CA3177398A1 (ru)
CL (5) CL2018002797A1 (ru)
CO (1) CO2018010547A2 (ru)
CR (2) CR20180480A (ru)
DK (1) DK3436030T3 (ru)
EA (1) EA201891992A1 (ru)
ES (1) ES2930058T3 (ru)
HR (1) HRP20221348T1 (ru)
HU (1) HUE060645T2 (ru)
IL (1) IL262041A (ru)
LT (1) LT3436030T (ru)
MA (1) MA43603A1 (ru)
MX (2) MX2018012019A (ru)
MY (1) MY197669A (ru)
PE (3) PE20211418A1 (ru)
PH (1) PH12018502113A1 (ru)
PL (1) PL3436030T3 (ru)
PT (1) PT3436030T (ru)
RS (1) RS63735B1 (ru)
SG (2) SG10201912519VA (ru)
SI (1) SI3436030T1 (ru)
TW (4) TW202319537A (ru)
UA (1) UA123276C2 (ru)
WO (1) WO2017173384A1 (ru)

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