CN102203132A - Pd-1拮抗剂的组合物和使用方法 - Google Patents

Pd-1拮抗剂的组合物和使用方法 Download PDF

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Publication number
CN102203132A
CN102203132A CN2009801422563A CN200980142256A CN102203132A CN 102203132 A CN102203132 A CN 102203132A CN 2009801422563 A CN2009801422563 A CN 2009801422563A CN 200980142256 A CN200980142256 A CN 200980142256A CN 102203132 A CN102203132 A CN 102203132A
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polypeptide
amino acids
toughener
cancer
continuous amino
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所罗门·兰格曼
琳达·刘
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Amplimmune Inc
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Amplimmune Inc
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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CN2009801422563A 2008-08-25 2009-08-25 Pd-1拮抗剂的组合物和使用方法 Pending CN102203132A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US9170908P 2008-08-25 2008-08-25
US9170508P 2008-08-25 2008-08-25
US9169408P 2008-08-25 2008-08-25
US61/091,694 2008-08-25
US61/091,709 2008-08-25
US61/091,705 2008-08-25
US21169709P 2009-04-02 2009-04-02
US61/211,697 2009-04-02
PCT/US2009/004825 WO2010027423A2 (en) 2008-08-25 2009-08-25 Compositions of pd-1 antagonists and methods of use

Publications (1)

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CN102203132A true CN102203132A (zh) 2011-09-28

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EP (2) EP2927240A1 (enExample)
JP (1) JP5798919B2 (enExample)
KR (1) KR20110050529A (enExample)
CN (1) CN102203132A (enExample)
AU (1) AU2009288730B2 (enExample)
CA (1) CA2734908A1 (enExample)
CL (1) CL2011000423A1 (enExample)
CO (1) CO6341574A2 (enExample)
CY (1) CY1116816T1 (enExample)
DK (1) DK2350129T3 (enExample)
DO (1) DOP2011000059A (enExample)
EA (2) EA023148B1 (enExample)
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HU (1) HUE027525T2 (enExample)
IL (1) IL211298A0 (enExample)
MA (1) MA32646B1 (enExample)
MX (1) MX2011002252A (enExample)
NZ (1) NZ591130A (enExample)
PE (1) PE20110435A1 (enExample)
PL (1) PL2350129T3 (enExample)
PT (1) PT2350129E (enExample)
RS (1) RS54233B1 (enExample)
SI (1) SI2350129T1 (enExample)
SM (1) SMT201500212B (enExample)
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Cited By (11)

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CN105492463A (zh) * 2013-08-20 2016-04-13 默沙东公司 肿瘤免疫调节
CN105983097A (zh) * 2015-01-28 2016-10-05 华中科技大学同济医学院附属协和医院 一种抗肿瘤制剂及其制备方法
CN106102774A (zh) * 2013-12-17 2016-11-09 豪夫迈·罗氏有限公司 包含ox40结合激动剂和pd‑1轴结合拮抗剂的组合疗法
CN106164676A (zh) * 2014-01-06 2016-11-23 爱科谱迅病理研究公司 针对pd‑l1的srm测定
CN106255510A (zh) * 2014-03-05 2016-12-21 百时美施贵宝公司 使用抗pd‑1抗体与另一抗癌剂的组合治疗肾癌
CN106687124A (zh) * 2014-08-07 2017-05-17 学校法人兵库医科大学 并用il‑18与分子靶向抗体的癌治疗药
CN109662966A (zh) * 2017-10-16 2019-04-23 北京莱科金基因科技有限责任公司 伊曲茶碱在制备用于肿瘤治疗的药物中的用途
CN109906088A (zh) * 2016-08-26 2019-06-18 奥野哲治 微血管血流减少剂及其应用
CN111093669A (zh) * 2017-08-14 2020-05-01 法斯瑞斯公司 用于治疗癌症的腺苷受体拮抗剂的微颗粒制剂
US10730951B2 (en) 2014-03-31 2020-08-04 Genentech, Inc. Anti-OX40 antibodies and methods of use
CN114432441A (zh) * 2022-01-11 2022-05-06 中国人民解放军陆军军医大学第一附属医院 一种pd-1修饰的金复合硒化铜纳米粒子及其在介导光热靶向治疗癌症方面的应用

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