NO324264B1 - Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmate samt medikament for medisinsk bruk. - Google Patents

Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmate samt medikament for medisinsk bruk. Download PDF

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Publication number
NO324264B1
NO324264B1 NO19994869A NO994869A NO324264B1 NO 324264 B1 NO324264 B1 NO 324264B1 NO 19994869 A NO19994869 A NO 19994869A NO 994869 A NO994869 A NO 994869A NO 324264 B1 NO324264 B1 NO 324264B1
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NO
Norway
Prior art keywords
antibody
vegf
seq
human
antibody according
Prior art date
Application number
NO19994869A
Other languages
English (en)
Norwegian (no)
Other versions
NO994869D0 (no
NO994869L (no
Inventor
Leonard G Presta
Manuel Baca
James A Wells
Henry B Lowman
Yvonne Man-Yee Chen
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27125626&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO324264(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/908,469 external-priority patent/US6884879B1/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of NO994869D0 publication Critical patent/NO994869D0/no
Publication of NO994869L publication Critical patent/NO994869L/no
Publication of NO324264B1 publication Critical patent/NO324264B1/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Air Bags (AREA)
  • Steering Control In Accordance With Driving Conditions (AREA)
NO19994869A 1997-04-07 1999-10-06 Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmate samt medikament for medisinsk bruk. NO324264B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83350497A 1997-04-07 1997-04-07
US08/908,469 US6884879B1 (en) 1997-04-07 1997-08-06 Anti-VEGF antibodies
PCT/US1998/006604 WO1998045331A2 (en) 1997-04-07 1998-04-03 Anti-vegf antibodies

Publications (3)

Publication Number Publication Date
NO994869D0 NO994869D0 (no) 1999-10-06
NO994869L NO994869L (no) 1999-12-06
NO324264B1 true NO324264B1 (no) 2007-09-17

Family

ID=27125626

Family Applications (3)

Application Number Title Priority Date Filing Date
NO19994869A NO324264B1 (no) 1997-04-07 1999-10-06 Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmate samt medikament for medisinsk bruk.
NO2007014C NO2007014I2 (no) 1997-04-07 2007-12-20 Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmåte samt medikament for medisinsk bruk
NO2007015C NO2007015I1 (no) 1997-04-07 2007-12-20 Ranibizumab

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO2007014C NO2007014I2 (no) 1997-04-07 2007-12-20 Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmåte samt medikament for medisinsk bruk
NO2007015C NO2007015I1 (no) 1997-04-07 2007-12-20 Ranibizumab

Country Status (25)

Country Link
US (2) US7060269B1 (https=)
EP (4) EP1325932B9 (https=)
JP (1) JP3957765B2 (https=)
KR (2) KR100816621B1 (https=)
CN (1) CN100480269C (https=)
AT (2) ATE293640T1 (https=)
AU (1) AU743758B2 (https=)
BR (1) BRPI9809387B8 (https=)
CA (1) CA2286330C (https=)
CY (3) CY2005008I2 (https=)
DE (5) DE69836729T2 (https=)
DK (2) DK1325932T5 (https=)
ES (2) ES2273415T3 (https=)
FR (2) FR05C0020I2 (https=)
GE (1) GEP20105118B (https=)
IL (1) IL132240A0 (https=)
LT (1) LTPA2005005I1 (https=)
LU (2) LU91167I2 (https=)
NL (2) NL300193I2 (https=)
NO (3) NO324264B1 (https=)
NZ (1) NZ500078A (https=)
PT (1) PT1325932E (https=)
SI (1) SI1325932T1 (https=)
TR (1) TR199903123T2 (https=)
WO (1) WO1998045331A2 (https=)

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CY2005008I2 (el) 2017-11-14
DE122007000021I1 (de) 2007-05-24
DK1325932T5 (da) 2005-10-03
NO994869D0 (no) 1999-10-06
CN1259962A (zh) 2000-07-12
EP1650220A3 (en) 2006-05-03
DE69829891T2 (de) 2005-10-06
EP1325932A3 (en) 2003-10-29
EP1787999B1 (en) 2010-08-04
KR100870353B1 (ko) 2008-11-25
DE122005000026I1 (de) 2005-08-04
LU91320I2 (fr) 2007-04-30
BRPI9809387B8 (pt) 2021-05-25
NL300278I1 (nl) 2007-06-01
EP1650220A2 (en) 2006-04-26
GEP20105118B (en) 2010-11-25
DE69836729D1 (de) 2007-02-08
NO2007015I1 (no) 2008-01-14
ATE349470T1 (de) 2007-01-15
NL300193I1 (nl) 2005-07-01
NO2007015I2 (https=) 2011-11-28
EP1325932A2 (en) 2003-07-09
CN100480269C (zh) 2009-04-22
EP0973804A2 (en) 2000-01-26
US7060269B1 (en) 2006-06-13
NO994869L (no) 1999-12-06
CY2007012I2 (el) 2009-11-04
NO2007014I2 (no) 2011-02-21
KR20080003453A (ko) 2008-01-07
DK0973804T3 (da) 2007-05-07
US7297334B2 (en) 2007-11-20
CY2005008I1 (el) 2009-11-04
HK1023577A1 (en) 2000-09-15
NO2007014I1 (no) 2008-01-14
LU91320I9 (https=) 2018-12-31
CY2007012I1 (el) 2009-11-04
PT1325932E (pt) 2005-06-30
FR07C0017I2 (fr) 2008-05-09
FR05C0020I2 (fr) 2008-05-09
ES2273415T3 (es) 2007-05-01
JP2001509817A (ja) 2001-07-24
EP1787999A1 (en) 2007-05-23
FR07C0017I1 (fr) 2007-04-27
KR100816621B1 (ko) 2008-03-24
LTPA2005005I1 (lt) 2017-11-27
AU743758B2 (en) 2002-02-07
DE69829891D1 (de) 2005-05-25
NZ500078A (en) 2001-10-26
HK1084402A1 (en) 2006-07-28
WO1998045331A3 (en) 1998-12-03
EP0973804B1 (en) 2006-12-27
ES2236634T3 (es) 2005-07-16
US20050112126A1 (en) 2005-05-26
NL300278I2 (nl) 2007-10-01
DE122005000050I1 (de) 2005-12-29
FR05C0020I1 (https=) 2005-05-27
KR20080003452A (ko) 2008-01-07
SI1325932T1 (https=) 2005-08-31
DE69836729T2 (de) 2007-12-13
NL300193I2 (nl) 2005-10-03
WO1998045331A2 (en) 1998-10-15

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