GB699812A
(en)
|
1950-11-29 |
1953-11-18 |
British Ind Solvents Ltd |
Manufacture of substituted pyrimidones
|
DE1249281B
(es)
|
1963-05-18 |
|
|
|
DE1670912C3
(de)
|
1967-08-18 |
1981-06-11 |
Bayer Ag, 5090 Leverkusen |
Herbizide Mittel auf Basis von 1,2,4-Triazin-5-onen
|
GB1377642A
(en)
|
1971-01-14 |
1974-12-18 |
Koninklijke Gist Spiritus |
Penicillanic and cephalosporanic acid derivatives
|
US3960949A
(en)
*
|
1971-04-02 |
1976-06-01 |
Schering Aktiengesellschaft |
1,2-Biguanides
|
DE2142317A1
(de)
|
1971-08-24 |
1973-03-01 |
Bayer Ag |
Hypnotisches mittel
|
DE2150686A1
(de)
*
|
1971-10-12 |
1973-04-19 |
Basf Ag |
6-amino-uracil-5-carbonsaeurethioamide
|
US3838128A
(en)
*
|
1971-11-22 |
1974-09-24 |
American Cyanamid Co |
Process for the preparation of certain n-3-substituted-6-(trichloromethyl)uracils
|
BE792206A
(es)
|
1971-12-02 |
1973-06-01 |
Byk Gulden Lomberg Chem Fab |
|
AU5996573A
(en)
|
1972-09-11 |
1975-03-06 |
Commonwealth Scientific And Industrial Research Organisation |
Pyridinium salts
|
US3823135A
(en)
|
1972-12-26 |
1974-07-09 |
Shell Oil Co |
Pyrimidone herbicides
|
GB1464248A
(en)
|
1973-11-01 |
1977-02-09 |
Ici Ltd |
Substituted triazinediones their preparation and use as herbicides
|
DE2361551A1
(de)
|
1973-12-11 |
1975-06-19 |
Basf Ag |
Wasserloesliche azofarbstoffe
|
DE2500024A1
(de)
|
1975-01-02 |
1976-07-08 |
Basf Ag |
Wasserloesliche azofarbstoffe
|
JPS535180A
(en)
|
1976-07-01 |
1978-01-18 |
Sumitomo Chem Co Ltd |
Preparation of 3,4-dihydro-2 (1h) quinazoline derivatives
|
DE2720085A1
(de)
|
1977-05-05 |
1978-11-16 |
Hoechst Ag |
Pyrimido(6,1-a)isochinolin-2-on- derivate
|
US4494978A
(en)
*
|
1976-12-30 |
1985-01-22 |
Chevron Research Company |
Herbicidal N-(N'-hydrocarbyloxycarbamylalkyl)-2,6-dialkyl-alpha-haloacetanilides
|
DE3011809A1
(de)
*
|
1980-03-27 |
1981-10-01 |
Cassella Ag, 6000 Frankfurt |
Pyrimidyl-chinazoline, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und ihre verwendung
|
CH657851A5
(de)
|
1983-06-28 |
1986-09-30 |
Ciba Geigy Ag |
Chromogene chinazolonverbindungen.
|
AR240698A1
(es)
|
1985-01-19 |
1990-09-28 |
Takeda Chemical Industries Ltd |
Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
|
EP0237289A3
(en)
|
1986-03-14 |
1988-07-27 |
Takeda Chemical Industries, Ltd. |
Pyrazolo [3,4-d] pyrimidine derivatives, their production and use
|
US5614492A
(en)
|
1986-05-05 |
1997-03-25 |
The General Hospital Corporation |
Insulinotropic hormone GLP-1 (7-36) and uses thereof
|
ES2137915T3
(es)
|
1987-09-04 |
2000-01-01 |
Beecham Group Plc |
Derivados de tiazolidindiona sustituida.
|
US4935493A
(en)
*
|
1987-10-06 |
1990-06-19 |
E. I. Du Pont De Nemours And Company |
Protease inhibitors
|
JPH01143895A
(ja)
*
|
1987-11-30 |
1989-06-06 |
Meiji Seika Kaisha Ltd |
ピリミジン誘導体
|
FR2631625B1
(fr)
*
|
1988-05-17 |
1992-10-16 |
Synthelabo |
Derives de phenyl-6 piperazinylalkyl-3 1h,3h-pyrimidinedione-2,4, leur preparation et leur application en therapeutique
|
GB8900382D0
(en)
|
1989-01-09 |
1989-03-08 |
Janssen Pharmaceutica Nv |
2-aminopyrimidinone derivatives
|
US5433955A
(en)
|
1989-01-23 |
1995-07-18 |
Akzo N.V. |
Site specific in vivo activation of therapeutic drugs
|
IE63502B1
(en)
|
1989-04-21 |
1995-05-03 |
Zeneca Ltd |
Aminopyrimidine derivatives useful for treating cardiovascular disorders
|
USRE37979E1
(en)
*
|
1989-09-29 |
2003-02-04 |
Mitsubishi Chemical Corporation |
Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof
|
US5814460A
(en)
|
1990-02-14 |
1998-09-29 |
Diatide, Inc. |
Method for generating and screening useful peptides
|
US5366862A
(en)
|
1990-02-14 |
1994-11-22 |
Receptor Laboratories, Inc. |
Method for generating and screening useful peptides
|
JP3032844B2
(ja)
*
|
1990-02-15 |
2000-04-17 |
武田薬品工業株式会社 |
ピリミジンジオン誘導体
|
CA2036304C
(en)
*
|
1990-02-15 |
2001-04-17 |
Takehiko Naka |
Pyrimidinedione derivatives, their production and use
|
US5462928A
(en)
|
1990-04-14 |
1995-10-31 |
New England Medical Center Hospitals, Inc. |
Inhibitors of dipeptidyl-aminopeptidase type IV
|
DE4110019C2
(de)
|
1991-03-27 |
2000-04-13 |
Merck Patent Gmbh |
Imidazopyridine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
|
US5387512A
(en)
*
|
1991-06-07 |
1995-02-07 |
Merck & Co. Inc. |
Preparation of 3-[z-benzoxazol-2-yl)ethyl]-5-(1-hydroxyethyl)-6-methyl-2-(1H)-pyridinone by biotransformation
|
US6825169B1
(en)
|
1991-10-22 |
2004-11-30 |
Trustees Of Tufts College |
Inhibitors of dipeptidyl-aminopeptidase type IV
|
CA2121369C
(en)
|
1991-10-22 |
2003-04-29 |
William W. Bachovchin |
Inhibitors of dipeptidyl-aminopeptidase type iv
|
US5350752A
(en)
|
1991-12-16 |
1994-09-27 |
E. R. Squibb & Sons, Inc. |
Dihydropyrimidine derivatives
|
DE4141788A1
(de)
|
1991-12-18 |
1993-06-24 |
Merck Patent Gmbh |
Imidazopyridine
|
DE4208050A1
(de)
*
|
1992-03-13 |
1993-09-23 |
Bayer Ag |
Azolylmethyl-fluorcyclopropyl-derivate
|
DE4305602A1
(de)
|
1992-06-17 |
1993-12-23 |
Merck Patent Gmbh |
Imidazopyridine
|
ZA936492B
(en)
|
1992-09-10 |
1995-03-02 |
Lilly Co Eli |
Compounds useful as hypoglycemic agents and for treating Alzheimer's disease.
|
IL106998A0
(en)
|
1992-09-17 |
1993-12-28 |
Univ Florida |
Brain-enhanced delivery of neuroactive peptides by sequential metabolism
|
JP3481984B2
(ja)
*
|
1992-12-29 |
2003-12-22 |
武田薬品工業株式会社 |
ピリドピリミジン誘導体、その製造方法および用途
|
US5811281A
(en)
|
1993-07-12 |
1998-09-22 |
Cornell Research Foundation, Inc. |
Immortalized intestinal epithelial cell lines
|
US5683966A
(en)
*
|
1993-08-11 |
1997-11-04 |
Fmc Corporation |
Herbicidal 3-(substituted-benzyl)-1-methyl-6-trifluoromethyluracils
|
US5391541A
(en)
*
|
1993-08-11 |
1995-02-21 |
Fmc Corporation |
Herbicidal 3-(substituted-benzyl)-1-methyl-6-trifluoromethyluracils
|
IL111785A0
(en)
*
|
1993-12-03 |
1995-01-24 |
Ferring Bv |
Dp-iv inhibitors and pharmaceutical compositions containing them
|
DE4341453A1
(de)
|
1993-12-06 |
1995-06-08 |
Merck Patent Gmbh |
Imidazopyridine
|
EP0749974B1
(en)
|
1994-03-08 |
2001-06-27 |
Otsuka Pharmaceutical Factory, Inc. |
Phosphonic diester derivative
|
US5580979A
(en)
|
1994-03-15 |
1996-12-03 |
Trustees Of Tufts University |
Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions
|
US5543396A
(en)
|
1994-04-28 |
1996-08-06 |
Georgia Tech Research Corp. |
Proline phosphonate derivatives
|
EP0764151A2
(en)
|
1994-06-10 |
1997-03-26 |
Universitaire Instelling Antwerpen |
Purification of serine protease and synthetic inhibitors thereof
|
US5601986A
(en)
*
|
1994-07-14 |
1997-02-11 |
Amgen Inc. |
Assays and devices for the detection of extrahepatic biliary atresia
|
DE4432860A1
(de)
|
1994-09-15 |
1996-03-21 |
Merck Patent Gmbh |
Imidazopyridine
|
US5512549A
(en)
|
1994-10-18 |
1996-04-30 |
Eli Lilly And Company |
Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
|
US5614379A
(en)
*
|
1995-04-26 |
1997-03-25 |
Eli Lilly And Company |
Process for preparing anti-obesity protein
|
US6325989B1
(en)
|
1995-06-01 |
2001-12-04 |
Dana-Farber Cancer Institute, Inc. |
Form of dipeptidylpeptidase IV (CD26) found in human serum
|
JP2002515724A
(ja)
|
1995-06-01 |
2002-05-28 |
ダナ−ファーバー キャンサー インスティテュート インコーポレイテッド |
ヒト血清中に見出されたジペプチジルペプチダーゼiv(cd26)の新規形態、その抗体および利用法
|
PT748800E
(pt)
|
1995-06-09 |
2001-10-30 |
Hoffmann La Roche |
Derivados de pirimidinadiona pirimidinatriona triazinadiona como antagonistas do receptor alfa-1-adrenergico
|
JPH0928376A
(ja)
|
1995-07-21 |
1997-02-04 |
Ajinomoto Co Inc |
新規ジペプチジルペプチダーゼivとその製造方法
|
EP1325941B1
(de)
|
1995-10-13 |
2005-06-01 |
Crompton Vinyl Additives GmbH |
Stabilisatorkombinationen für chlorhaltige Polymere
|
DE19616486C5
(de)
|
1996-04-25 |
2016-06-30 |
Royalty Pharma Collection Trust |
Verfahren zur Senkung des Blutglukosespiegels in Säugern
|
US20020006899A1
(en)
|
1998-10-06 |
2002-01-17 |
Pospisilik Andrew J. |
Use of dipeptidyl peptidase IV effectors for lowering blood pressure in mammals
|
US5965532A
(en)
|
1996-06-28 |
1999-10-12 |
Trustees Of Tufts College |
Multivalent compounds for crosslinking receptors and uses thereof
|
US5885997A
(en)
*
|
1996-07-01 |
1999-03-23 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
AU744518B2
(en)
|
1996-07-01 |
2002-02-28 |
Dr. Reddy's Laboratories Limited |
Novel heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
US6006753A
(en)
|
1996-08-30 |
1999-12-28 |
Eli Lilly And Company |
Use of GLP-1 or analogs to abolish catabolic changes after surgery
|
US6458924B2
(en)
|
1996-08-30 |
2002-10-01 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
US7235627B2
(en)
|
1996-08-30 |
2007-06-26 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
US6011155A
(en)
|
1996-11-07 |
2000-01-04 |
Novartis Ag |
N-(substituted glycyl)-2-cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
GB9702701D0
(en)
|
1997-02-01 |
1997-04-02 |
Univ Newcastle Ventures Ltd |
Quinazolinone compounds
|
US20030060434A1
(en)
*
|
1997-02-18 |
2003-03-27 |
Loretta Nielsen |
Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms
|
US6100234A
(en)
|
1997-05-07 |
2000-08-08 |
Tufts University |
Treatment of HIV
|
AU7381098A
(en)
|
1997-05-16 |
1998-12-08 |
Novo Nordisk Biotech, Inc. |
Polypeptides having prolyl pipeptidyl aminopeptidase activity and nucleic acids encoding same
|
US6011786A
(en)
*
|
1997-06-06 |
2000-01-04 |
Ericsson Inc. |
Systems and methods for control channel communication in cellular radiotelephone systems
|
EP0897012A1
(en)
|
1997-07-05 |
1999-02-17 |
Societe Des Produits Nestle S.A. |
Cloning of the prolyl-dipeptidyl-peptidase from aspergillus oryzae
|
US6235493B1
(en)
*
|
1997-08-06 |
2001-05-22 |
The Regents Of The University Of California |
Amino acid substituted-cresyl violet, synthetic fluorogenic substrates for the analysis of agents in individual in vivo cells or tissue
|
KR100458403B1
(ko)
|
1997-09-29 |
2004-11-26 |
포인트 써러퓨틱스, 인크. |
생체외 조혈세포의 자극방법
|
US6485955B1
(en)
*
|
1997-10-06 |
2002-11-26 |
The Trustees Of Tufts University |
Quiescent cell dipeptidyl peptidase: a novel cytoplasmic serine protease
|
US6342611B1
(en)
*
|
1997-10-10 |
2002-01-29 |
Cytovia, Inc. |
Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
|
DE69839279T2
(de)
*
|
1997-11-18 |
2009-05-28 |
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai |
Neue physiologisch aktive substanz sulphostin, herstellung und verwendung derselben
|
FR2771004B1
(fr)
*
|
1997-11-19 |
2000-02-18 |
Inst Curie |
Utilisation de derives de benzhydryl sulfinyle pour la fabrication de medicaments ayant un effet eveillant dans des situations de troubles de la vigilance d'origine medicamenteuse
|
WO1999031226A1
(en)
*
|
1997-12-16 |
1999-06-24 |
Novo Nordisk A/S |
Polypeptides having aminopeptidase activity and nucleic acids encoding same
|
US6380357B2
(en)
*
|
1997-12-16 |
2002-04-30 |
Eli Lilly And Company |
Glucagon-like peptide-1 crystals
|
JP2002501889A
(ja)
|
1998-02-02 |
2002-01-22 |
トラスティーズ オブ タフツ カレッジ |
グルコース代謝を調節する方法、およびそれに関連する試薬
|
US20020061839A1
(en)
*
|
1998-03-09 |
2002-05-23 |
Scharpe Simon Lodewijk |
Serine peptidase modulators
|
FR2777283B1
(fr)
|
1998-04-10 |
2000-11-24 |
Adir |
Nouveaux composes peptidiques analogues du glucagon-peptide- 1 (7-37), leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
DE19816857A1
(de)
*
|
1998-04-16 |
1999-10-21 |
Boehringer Ingelheim Pharma |
Neue unsymmetrisch substituierte Xanthin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE19823831A1
(de)
|
1998-05-28 |
1999-12-02 |
Probiodrug Ges Fuer Arzneim |
Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen
|
AU765370B2
(en)
*
|
1998-06-05 |
2003-09-18 |
Point Therapeutics, Inc. |
Cyclic boroproline compounds
|
DE19828113A1
(de)
*
|
1998-06-24 |
2000-01-05 |
Probiodrug Ges Fuer Arzneim |
Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
|
DE19828114A1
(de)
|
1998-06-24 |
2000-01-27 |
Probiodrug Ges Fuer Arzneim |
Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
|
DK0967208T3
(da)
|
1998-06-26 |
2002-11-18 |
Crompton Vinyl Additives Gmbh |
I 5-stilling substituerede 6-aminouraciler som stabilisatorer for halogenholdige polymerer
|
EP0967245A1
(de)
|
1998-06-26 |
1999-12-29 |
Witco Vinyl Additives GmbH |
1,3-disubstituierte 6-Aminouracile zum Stabilisieren von halogenhaltigen Polymeren
|
EP0967209B1
(de)
|
1998-06-26 |
2003-01-08 |
Crompton Vinyl Additives GmbH |
Neue NH2-modifizierte 6-Aminouracile als Stabilisatoren für halogenhaltige Polymere
|
US6129911A
(en)
|
1998-07-10 |
2000-10-10 |
Rhode Island Hospital, A Lifespan Partner |
Liver stem cell
|
DE19834591A1
(de)
|
1998-07-31 |
2000-02-03 |
Probiodrug Ges Fuer Arzneim |
Verfahren zur Steigerung des Blutglukosespiegels in Säugern
|
US6177437B1
(en)
*
|
1998-09-04 |
2001-01-23 |
University Of Massachusetts Medical Center |
Inhibitors of Herpes Simplex virus uracil-DNA glycosylase
|
US20030176357A1
(en)
|
1998-10-06 |
2003-09-18 |
Pospisilik Andrew J. |
Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels
|
CO5150173A1
(es)
|
1998-12-10 |
2002-04-29 |
Novartis Ag |
Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv
|
GB9906715D0
(en)
*
|
1999-03-23 |
1999-05-19 |
Ferring Bv |
Compositions for promoting growth
|
US6548529B1
(en)
|
1999-04-05 |
2003-04-15 |
Bristol-Myers Squibb Company |
Heterocyclic containing biphenyl aP2 inhibitors and method
|
DE19915388A1
(de)
*
|
1999-04-06 |
2000-10-12 |
Witco Vinyl Additives Gmbh |
4-Aminopyrimidinone und Oxazolidino-4-amino-pyrimidinone, Verfahren zu deren Herstellung und ihre Verwendung zum Stabilisieren von halogenhaltigen Polymeren
|
KR20000065885A
(ko)
*
|
1999-04-10 |
2000-11-15 |
최승주 |
항바이러스성 피리미딘다이온 유도체 및 그 제조방법
|
AU3958100A
(en)
|
1999-04-20 |
2000-11-02 |
Novo Nordisk A/S |
New compounds, their preparation and use
|
EA003922B1
(ru)
*
|
1999-05-17 |
2003-10-30 |
Конджачем, Инк. |
Продолжительно действующие инсулинотропные пептиды
|
DE19926233C1
(de)
|
1999-06-10 |
2000-10-19 |
Probiodrug Ges Fuer Arzneim |
Verfahren zur Herstellung von Thiazolidin
|
US6172081B1
(en)
*
|
1999-06-24 |
2001-01-09 |
Novartis Ag |
Tetrahydroisoquinoline 3-carboxamide derivatives
|
US6107317A
(en)
|
1999-06-24 |
2000-08-22 |
Novartis Ag |
N-(substituted glycyl)-thiazolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
US6110949A
(en)
|
1999-06-24 |
2000-08-29 |
Novartis Ag |
N-(substituted glycyl)-4-cyanothiazolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
US6528486B1
(en)
*
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
US6617340B1
(en)
|
1999-07-29 |
2003-09-09 |
Novartis Ag |
N-(substituted glycyl)-pyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
DE19940130A1
(de)
*
|
1999-08-24 |
2001-03-01 |
Probiodrug Ges Fuer Arzneim |
Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
|
US6340705B1
(en)
*
|
1999-09-10 |
2002-01-22 |
Monsanto Technology, Llc |
Use of α-linolenic acid metabolites for treatment or prevention of cancer
|
US6559188B1
(en)
*
|
1999-09-17 |
2003-05-06 |
Novartis Ag |
Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
|
US6414002B1
(en)
*
|
1999-09-22 |
2002-07-02 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
|
KR20020047185A
(ko)
|
1999-09-28 |
2002-06-21 |
플레믹 크리스티안 |
퀴나졸리논
|
US6447772B1
(en)
|
1999-10-01 |
2002-09-10 |
Klaire Laboratories, Inc. |
Compositions and methods relating to reduction of symptoms of autism
|
US6251391B1
(en)
*
|
1999-10-01 |
2001-06-26 |
Klaire Laboratories, Inc. |
Compositions containing dipepitidyl peptidase IV and tyrosinase or phenylalaninase for reducing opioid-related symptons
|
EP1229024A1
(en)
|
1999-10-08 |
2002-08-07 |
Meiji Seika Kaisha Ltd. |
m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM
|
US6261794B1
(en)
|
1999-10-14 |
2001-07-17 |
Saint Louis University |
Methods for identifying inhibitors of methionine aminopeptidases
|
US7230000B1
(en)
|
1999-10-27 |
2007-06-12 |
Cytokinetics, Incorporated |
Methods and compositions utilizing quinazolinones
|
US20040152745A1
(en)
|
1999-11-12 |
2004-08-05 |
Guilford Pharmaceuticals, Inc. |
Dipeptidyl peptidase IV inhibitors and methods of making and using dipeptidyl peptidase IV inhibitors
|
JP2003535034A
(ja)
|
1999-11-12 |
2003-11-25 |
ギルフォード ファーマシューティカルズ インコーポレイテッド |
ジペプチジルペプチダーゼiv阻害剤並びにジペプチジルペプチダーゼiv阻害剤の製造及び使用法
|
GB9928330D0
(en)
*
|
1999-11-30 |
2000-01-26 |
Ferring Bv |
Novel antidiabetic agents
|
WO2001041779A2
(en)
*
|
1999-12-08 |
2001-06-14 |
1149336 Ontario Inc. |
Combined use of glp-2 receptor agonist and chemotherapeutic agent in treatment
|
US6380398B2
(en)
|
2000-01-04 |
2002-04-30 |
Novo Nordisk A/S |
Therapeutically active and selective heterocyclic compounds that are inhibitors of the enzyme DPP-IV
|
JP2003520226A
(ja)
|
2000-01-21 |
2003-07-02 |
ノバルティス アクチエンゲゼルシャフト |
ジペプチジルペプチダーゼ−iv阻害剤および抗糖尿病薬剤を含む組合せ物
|
ATE548357T1
(de)
*
|
2000-01-25 |
2012-03-15 |
Neurocrine Biosciences Inc |
Gonadotropin freisetzende hormon rezeptor antagonisten und ihre verwandten verfahren
|
ES2218381T3
(es)
*
|
2000-01-27 |
2004-11-16 |
Eli Lilly And Company |
Procedimiento para solubilizar compuestos del peptido 1 de tipo glucagon.
|
US6569901B2
(en)
|
2000-01-28 |
2003-05-27 |
Novo Nordisk A/S |
Alkynyl-substituted propionic acid derivatives, their preparation and use
|
US7217722B2
(en)
|
2000-02-01 |
2007-05-15 |
Kirin Beer Kabushiki Kaisha |
Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
|
JP4088011B2
(ja)
*
|
2000-02-16 |
2008-05-21 |
株式会社東芝 |
半導体装置及びその製造方法
|
US6395767B2
(en)
*
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
US6448045B1
(en)
|
2000-03-10 |
2002-09-10 |
The Regents Of The University Of California |
Inducing insulin gene expression in pancreas cells expressing recombinant PDX-1
|
US6608038B2
(en)
|
2000-03-15 |
2003-08-19 |
Novartis Ag |
Methods and compositions for treatment of diabetes and related conditions via gene therapy
|
EP1136482A1
(en)
|
2000-03-23 |
2001-09-26 |
Sanofi-Synthelabo |
2-Amino-3-(alkyl)-pyrimidone derivatives as GSK3beta inhibitors
|
US6555519B2
(en)
*
|
2000-03-30 |
2003-04-29 |
Bristol-Myers Squibb Company |
O-glucosylated benzamide SGLT2 inhibitors and method
|
DK1283735T4
(da)
*
|
2000-03-31 |
2013-02-04 |
Royalty Pharma Collection Trust |
Fremgangsmåde til forbedring signalering af øceller ved diabetes mellitus og til forebyggelse deraf
|
US6573096B1
(en)
|
2000-04-01 |
2003-06-03 |
The Research Foundation At State University Of New York |
Compositions and methods for inhibition of cancer invasion and angiogenesis
|
US6545170B2
(en)
*
|
2000-04-13 |
2003-04-08 |
Pharmacia Corporation |
2-amino-5, 6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors
|
ATE502941T1
(de)
|
2000-04-25 |
2011-04-15 |
Icos Corp |
Hemmer der menschlichen phosphatidyl-inositol-3- kinase delta
|
GB0010183D0
(en)
|
2000-04-26 |
2000-06-14 |
Ferring Bv |
Inhibitors of dipeptidyl peptidase IV
|
GB0010188D0
(en)
*
|
2000-04-26 |
2000-06-14 |
Ferring Bv |
Inhibitors of dipeptidyl peptidase IV
|
US6783757B2
(en)
*
|
2000-06-01 |
2004-08-31 |
Kirkman Group, Inc. |
Composition and method for increasing exorphin catabolism to treat autism
|
TW583185B
(en)
|
2000-06-13 |
2004-04-11 |
Novartis Ag |
N-(substituted glycyl)-2-cyanopyrrolidines and pharmaceutical composition for inhibiting dipeptidyl peptidase-IV (DPP-IV) or for the prevention or treatment of diseases or conditions associated with elevated levels of DPP-IV comprising the same
|
US6432969B1
(en)
|
2000-06-13 |
2002-08-13 |
Novartis Ag |
N-(substituted glycyl)-2 cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
US6620821B2
(en)
|
2000-06-15 |
2003-09-16 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
US6627636B2
(en)
|
2000-06-15 |
2003-09-30 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
GB0014969D0
(en)
|
2000-06-19 |
2000-08-09 |
Smithkline Beecham Plc |
Novel method of treatment
|
US7078397B2
(en)
|
2000-06-19 |
2006-07-18 |
Smithkline Beecham Corporation |
Combinations of dipeptidyl peptidase IV inhibitors and other antidiabetic agents for the treatment of diabetes mellitus
|
US6558188B1
(en)
*
|
2000-06-22 |
2003-05-06 |
Hewlett Packard Development Company, L.P. |
Impedance controlled electrical connector assembly
|
AU2001268958B2
(en)
*
|
2000-07-04 |
2006-03-09 |
Novo Nordisk A/S |
Heterocyclic compounds, which are inhibitors of the enzyme dpp-iv
|
EP1561752A1
(en)
*
|
2000-07-04 |
2005-08-10 |
Novo Nordisk A/S |
Heterocyclic compounds that are inhibitors of the enzyme DPP-IV
|
JP2002042960A
(ja)
|
2000-07-25 |
2002-02-08 |
Yazaki Corp |
コネクタ支持機構
|
EA005817B1
(ru)
|
2000-08-01 |
2005-06-30 |
Фармасиа Корпорейшн |
Производные гексагидро-7-1h-азепин-2-илгексановой (или гексеновой) кислоты в качестве ингибиторов индуцибельной синтазы оксида азота
|
ES2311532T3
(es)
|
2000-08-04 |
2009-02-16 |
Warner-Lambert Company Llc |
2-(4-pirdil)amino-6-dialcoxifenil-pirido(2.3-d)pirimidin-7-onas.
|
ATE556048T1
(de)
|
2000-08-10 |
2012-05-15 |
Mitsubishi Tanabe Pharma Corp |
Prolinderivate und ihre verwendung als heilmittel
|
US20020165237A1
(en)
|
2000-08-11 |
2002-11-07 |
Fryburg David Albert |
Treatment of the insulin resistance syndrome
|
US20020037829A1
(en)
*
|
2000-08-23 |
2002-03-28 |
Aronson Peter S. |
Use of DPPIV inhibitors as diuretic and anti-hypertensive agents
|
US6900226B2
(en)
|
2000-09-06 |
2005-05-31 |
Hoffman-La Roche Inc. |
Neuropeptide Y antagonists
|
PE20020453A1
(es)
*
|
2000-09-27 |
2002-06-06 |
Merck & Co Inc |
Derivados del acido benzopirancarboxilico para el tratamiento de la diabetes y los trastornos de lipidos
|
US20020064736A1
(en)
|
2000-09-27 |
2002-05-30 |
Fuji Photo Film Co., Ltd. |
Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye
|
ATE407924T1
(de)
*
|
2000-10-06 |
2008-09-15 |
Mitsubishi Tanabe Pharma Corp |
Stickstoffhaltige, fünfgliedrige ringverbindungen
|
AU1313802A
(en)
|
2000-10-12 |
2002-04-22 |
Ferring Bv |
Novel serine protease genes related to dppiv
|
AUPR107800A0
(en)
*
|
2000-10-27 |
2000-11-23 |
University Of Sydney, The |
Peptide and nucleic acid molecule ii
|
ZA200302394B
(en)
|
2000-10-27 |
2004-03-29 |
Probiodrug Ag |
Method for the treatment of neurological and neuropsychological disorders.
|
BR0115055A
(pt)
|
2000-10-30 |
2003-12-30 |
Ortho Mcneil Pharm Inc |
Terapia de combinação compreendendo agentes anticonvulsantes e antidiabéticos
|
WO2002060434A2
(en)
|
2000-10-31 |
2002-08-08 |
Merck & Co., Inc. |
Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders
|
US6586198B2
(en)
|
2000-10-31 |
2003-07-01 |
Vanderbilt University |
Method of identifying susceptibility to angiotensin converting enzyme inhibto- and vasopeptidase-inhibitor-associated angioedema
|
US6864363B2
(en)
|
2000-11-08 |
2005-03-08 |
University Of Georgia Research Foundation, Inc. |
Dipeptidylpeptidases and methods of use
|
TWI243162B
(en)
*
|
2000-11-10 |
2005-11-11 |
Taisho Pharmaceutical Co Ltd |
Cyanopyrrolidine derivatives
|
US20030055052A1
(en)
*
|
2000-11-10 |
2003-03-20 |
Stefan Peters |
FAP-activated anti-tumor compounds
|
US20020155565A1
(en)
|
2000-11-10 |
2002-10-24 |
Pilar Garin-Chesa |
FAP-activated anti-tumor compounds
|
US20030203946A1
(en)
|
2000-11-17 |
2003-10-30 |
Carsten Behrens |
Glucagon antagonists/inverse agonists
|
HUP0500543A2
(hu)
*
|
2000-11-20 |
2005-09-28 |
Bristol-Myers Squibb Company |
Piridonszármazékok mint aP2 inhibitorok és a vegyületeket tartalmazó gyógyszerkészítmények
|
NZ526622A
(en)
|
2000-12-11 |
2006-07-28 |
Amgen Sf Llc |
CXCR3 antagonists
|
CA2433090A1
(en)
|
2000-12-27 |
2002-07-04 |
Kyowa Hakko Kogyo Co., Ltd. |
Dipeptidyl peptidase iv inhibitor
|
DE10100053A1
(de)
|
2001-01-02 |
2002-08-22 |
Keyneurotek Ag I G |
Verwendung von Enzyminhibitoren der Dipeptidylpeptidase IV sowie der Aminopeptidase N und pharmazeutischen Zubereitungen daraus zur Prävention und/oder Therapie Ischämie-bedingter akuter und chronischer neurodegenerativer Prozesse und Erkrankungen
|
MXPA03006918A
(es)
*
|
2001-02-02 |
2004-05-24 |
Takeda Chemical Industries Ltd |
Compuestos heterociclicos fusionados.
|
TWI255817B
(en)
|
2001-02-14 |
2006-06-01 |
Kissei Pharmaceutical |
Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
|
PT1757606E
(pt)
*
|
2001-02-24 |
2009-05-26 |
Boehringer Ingelheim Pharma |
Utilização de derivados de xantina como produto farmacêutico, bem como seu processo de preparação
|
US6337069B1
(en)
*
|
2001-02-28 |
2002-01-08 |
B.M.R.A. Corporation B.V. |
Method of treating rhinitis or sinusitis by intranasally administering a peptidase
|
JP4178816B2
(ja)
|
2001-03-15 |
2008-11-12 |
田辺三菱製薬株式会社 |
医薬組成物
|
SI1372650T1
(sl)
*
|
2001-03-19 |
2009-04-30 |
Novartis Ag |
Kombinacije, ki obsegajo antidiaroično sredstvo in epotilon ali epotilonski derivat
|
US7026316B2
(en)
|
2001-03-27 |
2006-04-11 |
Merck & Co., Inc. |
Dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
FR2822826B1
(fr)
*
|
2001-03-28 |
2003-05-09 |
Servier Lab |
Nouveaux derives sulfonyles d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
DE10115921A1
(de)
|
2001-03-30 |
2002-10-02 |
Boehringer Ingelheim Pharma |
Verfahren zur Herstellung von 4,6-Diaminopyrimido[5,4-d]pyrimidinen
|
US6890905B2
(en)
*
|
2001-04-02 |
2005-05-10 |
Prosidion Limited |
Methods for improving islet signaling in diabetes mellitus and for its prevention
|
GB0109146D0
(en)
|
2001-04-11 |
2001-05-30 |
Ferring Bv |
Treatment of type 2 diabetes
|
US6573287B2
(en)
|
2001-04-12 |
2003-06-03 |
Bristo-Myers Squibb Company |
2,1-oxazoline and 1,2-pyrazoline-based inhibitors of dipeptidyl peptidase IV and method
|
PE20021080A1
(es)
*
|
2001-04-12 |
2003-02-12 |
Boehringer Ingelheim Int |
Un anticuerpo especifico fapo bibh1 en el tratamiento del cancer
|
US7028450B2
(en)
*
|
2001-05-14 |
2006-04-18 |
F.R. Drake Company |
System and method of processing and packing disk-like objects
|
FR2824825B1
(fr)
*
|
2001-05-15 |
2005-05-06 |
Servier Lab |
Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
US20030060494A1
(en)
|
2001-05-18 |
2003-03-27 |
Nobuyuki Yasuda |
Pharmaceutical use of N-carbamoylazole derivatives
|
US7105556B2
(en)
*
|
2001-05-30 |
2006-09-12 |
Bristol-Myers Squibb Company |
Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method
|
US6794379B2
(en)
|
2001-06-06 |
2004-09-21 |
Tularik Inc. |
CXCR3 antagonists
|
CA2450579A1
(en)
|
2001-06-20 |
2003-01-03 |
Merck & Co., Inc. |
Dipeptidyl peptidase inhibitors for the treatment of diabetes
|
ATE318139T1
(de)
|
2001-06-20 |
2006-03-15 |
Merck & Co Inc |
Dipeptidylpeptidase-hemmer zur behandlung von diabetes
|
DE10150203A1
(de)
|
2001-10-12 |
2003-04-17 |
Probiodrug Ag |
Peptidylketone als Inhibitoren der DPIV
|
US20030130199A1
(en)
|
2001-06-27 |
2003-07-10 |
Von Hoersten Stephan |
Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
|
CN1321682C
(zh)
|
2001-06-27 |
2007-06-20 |
前体生物药物股份有限公司 |
新的二肽基肽酶iv抑制剂和它们作为抗癌药的用途
|
HUP0400321A2
(hu)
|
2001-06-27 |
2004-08-30 |
Smithkline Beecham Corp. |
Fluorpirrolidin-származékok mint dipeptidil-dipeptidáz inhibitorok és ezeket tartalmazó gyógyszerkészítmények
|
US7368421B2
(en)
*
|
2001-06-27 |
2008-05-06 |
Probiodrug Ag |
Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
|
US7183290B2
(en)
|
2001-06-27 |
2007-02-27 |
Smithkline Beecham Corporation |
Fluoropyrrolidines as dipeptidyl peptidase inhibitors
|
DE60223920T2
(de)
|
2001-06-27 |
2008-11-13 |
Smithkline Beecham Corp. |
Pyrrolidine als dipeptidyl-peptidase-inhibitoren
|
WO2003002593A2
(en)
|
2001-06-27 |
2003-01-09 |
Probiodrug Ag |
Peptide structures useful for competitive modulation of dipeptidyl peptidase iv catalysis
|
DE10154689A1
(de)
|
2001-11-09 |
2003-05-22 |
Probiodrug Ag |
Substituierte Aminoketonverbindungen
|
US20030135023A1
(en)
|
2001-06-27 |
2003-07-17 |
Hans-Ulrich Demuth |
Peptide structures useful for competitive modulation of dipeptidyl peptidase IV catalysis
|
US6869947B2
(en)
*
|
2001-07-03 |
2005-03-22 |
Novo Nordisk A/S |
Heterocyclic compounds that are inhibitors of the enzyme DPP-IV
|
UA74912C2
(en)
*
|
2001-07-06 |
2006-02-15 |
Merck & Co Inc |
Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
|
WO2003007888A2
(en)
|
2001-07-20 |
2003-01-30 |
Adipogenix, Inc. |
Fat accumulation-modulating compounds
|
TW524754B
(en)
|
2001-07-24 |
2003-03-21 |
Nano Dynamics Inc |
Ink supplying cassette having under pressure regulation mechanism
|
EP1285922A1
(en)
|
2001-08-13 |
2003-02-26 |
Warner-Lambert Company |
1-Alkyl or 1-cycloalkyltriazolo[4,3-a]quinazolin-5-ones as phosphodiesterase inhibitors
|
US7279550B2
(en)
|
2001-08-13 |
2007-10-09 |
Probiodrug Ag |
Irreversible cysteine protease inhibitors of legumain
|
JP2003128551A
(ja)
|
2001-08-15 |
2003-05-08 |
Sankyo Co Ltd |
新規抗糖尿病医薬組成物
|
DE10143840A1
(de)
|
2001-09-06 |
2003-03-27 |
Probiodrug Ag |
Neue Inhibitoren der Dipeptidylpeptidase I
|
US6844316B2
(en)
*
|
2001-09-06 |
2005-01-18 |
Probiodrug Ag |
Inhibitors of dipeptidyl peptidase I
|
US20030186963A1
(en)
|
2001-09-14 |
2003-10-02 |
Dorwald Florencio Zaragoza |
Substituted piperidines
|
KR20040033048A
(ko)
|
2001-09-14 |
2004-04-17 |
미츠비시 웰파마 가부시키가이샤 |
티아졸리딘 유도체 및 이의 약학적 용도
|
US6673829B2
(en)
*
|
2001-09-14 |
2004-01-06 |
Novo Nordisk A/S |
Aminoazetidine,-pyrrolidine and -piperidine derivatives
|
WO2003024965A2
(en)
|
2001-09-19 |
2003-03-27 |
Novo Nordisk A/S |
Heterocyclic compounds that are inhibitors of the enzyme dpp-iv
|
CN104744461A
(zh)
|
2001-09-21 |
2015-07-01 |
百时美施贵宝公司 |
含有内酰胺的化合物及其衍生物作为Xa因子的抑制剂
|
ATE424393T1
(de)
|
2001-09-21 |
2009-03-15 |
Mitsubishi Tanabe Pharma Corp |
3-substituierte 4-pyrimidonderivate
|
AR043700A1
(es)
|
2001-09-21 |
2005-08-10 |
Mitsubishi Pharma Corp |
Derivados de 3-substituida-4-pirimidona
|
US7019010B2
(en)
|
2001-09-27 |
2006-03-28 |
Novertis Ag |
Combinations
|
RS26604A
(en)
*
|
2001-10-01 |
2006-12-15 |
Bristol Myers Squibb Company |
Spiro-hydantoin compounds useful as anti-inflamatory agents
|
WO2003030946A1
(en)
|
2001-10-09 |
2003-04-17 |
Novartis Ag |
Regulation of insulin production
|
US7064135B2
(en)
|
2001-10-12 |
2006-06-20 |
Novo Nordisk Inc. |
Substituted piperidines
|
TWI301834B
(en)
|
2001-10-22 |
2008-10-11 |
Eisai R&D Man Co Ltd |
Pyrimidone compound and pharmaceutical composition including the same
|
GB0125445D0
(en)
*
|
2001-10-23 |
2001-12-12 |
Ferring Bv |
Protease Inhibitors
|
US6861440B2
(en)
*
|
2001-10-26 |
2005-03-01 |
Hoffmann-La Roche Inc. |
DPP IV inhibitors
|
WO2003040114A1
(en)
*
|
2001-11-06 |
2003-05-15 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
|
US20030125304A1
(en)
|
2001-11-09 |
2003-07-03 |
Hans-Ulrich Demuth |
Substituted amino ketone compounds
|
US20030089935A1
(en)
*
|
2001-11-13 |
2003-05-15 |
Macronix International Co., Ltd. |
Non-volatile semiconductor memory device with multi-layer gate insulating structure
|
US20030093697A1
(en)
*
|
2001-11-13 |
2003-05-15 |
Lin Wen Chi |
Method for preventing unauthorized persons from entering and using a computer facility
|
AU2002360453C1
(en)
|
2001-11-26 |
2009-06-18 |
The Brigham And Women's Hospital, Inc. |
Methods for treating autoimmune disorders, and reagents related thereto
|
WO2003045918A1
(en)
|
2001-11-26 |
2003-06-05 |
Schering Corporation |
Piperidine-based mch antagonists for treatment of obesity and cns disorders
|
CA2837936A1
(en)
|
2001-11-26 |
2003-06-05 |
Trustees Of Tufts College |
Peptidomimetic inhibitors of post-proline cleaving enzymes
|
WO2003048081A2
(en)
|
2001-12-04 |
2003-06-12 |
Bristol-Myers Squibb Company |
Glycinamides as factor xa inhibitors
|
EP1458374A2
(en)
|
2001-12-14 |
2004-09-22 |
Novo Nordisk A/S |
Compounds and uses thereof for decreasing activity of hormone-sensitive lipase
|
AU2002351748B2
(en)
|
2001-12-21 |
2009-07-09 |
Novo Nordisk A/S |
Amide derivatives as GK activators
|
TW200301698A
(en)
|
2001-12-21 |
2003-07-16 |
Bristol Myers Squibb Co |
Acridone inhibitors of IMPDH enzyme
|
EP1466636A4
(en)
*
|
2001-12-25 |
2009-06-10 |
Kaneka Corp |
"Adsorptive Agent for Cytokine, Method for Adsorptive Removal and Device for Adsorptive Separation"
|
US6727261B2
(en)
*
|
2001-12-27 |
2004-04-27 |
Hoffman-La Roche Inc. |
Pyrido[2,1-A]Isoquinoline derivatives
|
WO2003059372A2
(en)
|
2001-12-29 |
2003-07-24 |
Novo Nordisk A/S |
Combined use of a glp-1 compound and a modulator of diabetic late complications
|
AU2003201274A1
(en)
|
2002-01-11 |
2003-07-24 |
Novo Nordisk A/S |
Compositions comprising inhibitors of dpp-iv and nep enzymes for the treatment of diabetes
|
US7192601B2
(en)
*
|
2002-01-18 |
2007-03-20 |
Walker Edward B |
Antimicrobial and sporicidal composition
|
AU2003218969A1
(en)
|
2002-02-01 |
2003-09-02 |
Probiodrug Ag |
Modulation of t lymphocytes using dp iv inhibitors
|
US7101898B2
(en)
|
2002-02-01 |
2006-09-05 |
Novo Nordisk A/S |
Amides of aminoalkyl-substituted azetidines, pyrrolidines, piperidines and azepanes
|
ATE472536T1
(de)
*
|
2002-02-13 |
2010-07-15 |
Hoffmann La Roche |
Pyridin- und pyrimidin-derivate
|
PL372488A1
(en)
|
2002-02-13 |
2005-07-25 |
F.Hoffmann-La Roche Ag |
Novel pyridine- and quinoline-derivatives
|
DE60301491T2
(de)
|
2002-02-27 |
2006-05-18 |
Pfizer Products Inc., Groton |
Acc-hemmer
|
SI1480961T1
(sl)
|
2002-02-28 |
2007-06-30 |
Prosidion Ltd |
Inhibitorji dpiv na osnovi glutaminila
|
DE60336901D1
(de)
|
2002-03-07 |
2011-06-09 |
X Ceptor Therapeutics Inc |
Chinazolinon modulatoren von nukleinrezeptoren
|
US20030232761A1
(en)
|
2002-03-28 |
2003-12-18 |
Hinke Simon A. |
Novel analogues of glucose-dependent insulinotropic polypeptide
|
KR20040105853A
(ko)
|
2002-04-08 |
2004-12-16 |
토렌트 파마슈티칼스 리미티드 |
티아졸리딘-4-카르보니트릴 및 유사체와디펩티딜-펩티다아제 억제제로서의 용도
|
US20040106802A1
(en)
|
2002-04-08 |
2004-06-03 |
Torrent Pharmaceuticals Ltd. |
Novel compounds and therapeutic uses thereof
|
JP2003300977A
(ja)
*
|
2002-04-10 |
2003-10-21 |
Sumitomo Pharmaceut Co Ltd |
キサンチン誘導体
|
AU2003228793B2
(en)
|
2002-04-30 |
2008-01-03 |
Trustees Of Tufts College |
Smart Pro-Drugs of Serine Protease Inhibitors
|
TW200307667A
(en)
*
|
2002-05-06 |
2003-12-16 |
Bristol Myers Squibb Co |
Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors
|
US7057046B2
(en)
*
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
EP1551834B1
(en)
|
2002-05-23 |
2010-08-25 |
Novartis Vaccines and Diagnostics, Inc. |
Substituted quinazolinone compounds
|
GB0212412D0
(en)
|
2002-05-29 |
2002-07-10 |
Novartis Ag |
Combination of organic compounds
|
AU2003233010A1
(en)
|
2002-06-04 |
2003-12-19 |
Pfizer Products Inc. |
Process for the preparation of 3,3,4,4-tetrafluoropyrrolidine and derivatives thereof
|
US6710040B1
(en)
*
|
2002-06-04 |
2004-03-23 |
Pfizer Inc. |
Fluorinated cyclic amides as dipeptidyl peptidase IV inhibitors
|
EP1514552A4
(en)
|
2002-06-06 |
2008-04-02 |
Eisai R&D Man Co Ltd |
NEW MILED IMIDAZOLE DERIVATIVE
|
US20040009972A1
(en)
*
|
2002-06-17 |
2004-01-15 |
Ding Charles Z. |
Benzodiazepine inhibitors of mitochondial F1F0 ATP hydrolase and methods of inhibiting F1F0 ATP hydrolase
|
MXPA04012860A
(es)
|
2002-06-17 |
2005-09-20 |
Smithkline Beecham Corp |
Proceso quimico.
|
SE0201976D0
(sv)
|
2002-06-24 |
2002-06-24 |
Astrazeneca Ab |
Novel compounds
|
US20040054171A1
(en)
*
|
2002-07-04 |
2004-03-18 |
Jensen Anette Frost |
Polymorphic forms of a 4H-thieno[3,2-E]-1,2,4-thiadiazine 1,1-dioxide derivative
|
ES2306781T3
(es)
|
2002-08-09 |
2008-11-16 |
Prosidion Ltd. |
Inhibidores de la dipeptidil-peptidasa iv para disminucion de la tasa de aumento cronico de peso.
|
JP2006500351A
(ja)
*
|
2002-08-13 |
2006-01-05 |
ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー |
マトリックスメタロプロテアーゼ−13阻害剤としてのピリミジン−2,4−ジオン誘導体
|
US7407955B2
(en)
*
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
EP2308878A3
(de)
|
2002-08-21 |
2011-10-26 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
8-[3-Amino-Piperidin-1-YL] -Xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
US7495005B2
(en)
|
2002-08-22 |
2009-02-24 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, their preparation and their use in pharmaceutical compositions
|
US6998502B1
(en)
*
|
2002-09-05 |
2006-02-14 |
Sabinsa Corporation |
Convenient process of manufacture for difluoromethylornithine and related compounds
|
EP1398032A1
(en)
|
2002-09-10 |
2004-03-17 |
PheneX Pharmaceuticals AG |
4-Oxo-quinazolines as LXR nuclear receptor binding compounds
|
JP2004123738A
(ja)
|
2002-09-11 |
2004-04-22 |
Takeda Chem Ind Ltd |
徐放性製剤
|
US20050176622A1
(en)
|
2002-09-18 |
2005-08-11 |
Kerstin Kuhn-Wache |
Secondary binding site of dipeptidyl peptidase IV (DPIV)
|
US20040058876A1
(en)
*
|
2002-09-18 |
2004-03-25 |
Torsten Hoffmann |
Secondary binding site of dipeptidyl peptidase IV (DP IV)
|
US7262207B2
(en)
|
2002-09-19 |
2007-08-28 |
Abbott Laboratories |
Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
|
US6869966B2
(en)
*
|
2002-09-30 |
2005-03-22 |
Banyu Pharmaceutical Co., Ltd. |
N-substituted-2-oxodihydropyridine derivatives
|
CN100383129C
(zh)
|
2002-10-18 |
2008-04-23 |
默克公司 |
用于治疗或预防糖尿病的β-氨基杂环二肽酰肽酶抑制剂
|
EP1553947A4
(en)
|
2002-10-21 |
2006-11-29 |
Bristol Myers Squibb Co |
QUINAZOLINONES AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
|
US6995180B2
(en)
|
2002-10-23 |
2006-02-07 |
Bristol Myers Squibb Company |
Glycinenitrile-based inhibitors of dipeptidyl peptidase IV and methods
|
US7482337B2
(en)
|
2002-11-08 |
2009-01-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
|
BR0316327A
(pt)
|
2002-11-18 |
2005-09-27 |
Pfizer Prod Inc |
Amidas cìclicas fluorinadas inibidoras de dipeptidilpeptidase iv
|
DE10254304A1
(de)
|
2002-11-21 |
2004-06-03 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
US7109192B2
(en)
*
|
2002-12-03 |
2006-09-19 |
Boehringer Ingelheim Pharma Gmbh & Co Kg |
Substituted imidazo-pyridinones and imidazo-pyridazinones, the preparation thereof and their use as pharmaceutical compositions
|
DE10256264A1
(de)
|
2002-12-03 |
2004-06-24 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Imidazo-pyridinone und Imidazo-pyridazinone, ihre Herstellung und ihre Verwendung als Arzneimittel
|
US7135467B2
(en)
|
2003-01-13 |
2006-11-14 |
Bristol-Myers Squibb Company |
HIV integrase inhibitors
|
US7148246B2
(en)
|
2003-02-27 |
2006-12-12 |
Sanofi-Aventis Deutschland Gmbh |
Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
|
US20050014732A1
(en)
*
|
2003-03-14 |
2005-01-20 |
Pharmacia Corporation |
Combination of an aldosterone receptor antagonist and an anti-diabetic agent
|
EP1608317B1
(en)
|
2003-03-25 |
2012-09-26 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
TWI357408B
(en)
|
2003-03-26 |
2012-02-01 |
Mitsubishi Tanabe Pharma Corp |
3-substituted-4-pyrimidone derivatives
|
US7371871B2
(en)
*
|
2003-05-05 |
2008-05-13 |
Probiodrug Ag |
Inhibitors of glutaminyl cyclase
|
CN101837127A
(zh)
*
|
2003-05-05 |
2010-09-22 |
前体生物药物股份公司 |
谷氨酰胺酰基和谷氨酸环化酶效应物的应用
|
US20040229848A1
(en)
|
2003-05-05 |
2004-11-18 |
Hans-Ulrich Demuth |
Glutaminyl based DP IV-inhibitors
|
US7638638B2
(en)
|
2003-05-14 |
2009-12-29 |
Takeda San Diego, Inc. |
Dipeptidyl peptidase inhibitors
|
US7566707B2
(en)
*
|
2003-06-18 |
2009-07-28 |
Boehringer Ingelheim International Gmbh |
Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions
|
CA2528784C
(en)
|
2003-06-20 |
2012-02-21 |
Markus Boehringer |
Hexahydropyridoisoquinolines as dpp-iv inhibitors
|
PT1638970E
(pt)
|
2003-06-20 |
2010-12-13 |
Hoffmann La Roche |
Derivados de pirid(2,1-a)isoquinolina como inibidores de dpp-iv
|
JO2625B1
(en)
*
|
2003-06-24 |
2011-11-01 |
ميرك شارب اند دوم كوربوريشن |
Phosphoric acid salts of dipeptidyl betidase inhibitor 4
|
DE602004020638D1
(de)
*
|
2003-07-07 |
2009-05-28 |
Neurocrine Biosciences Inc |
Pyrimidin-2,4-dion-derivate als gonadotropin freisetzende hormon-rezeptor-antagonisten
|
EP1646389B1
(en)
*
|
2003-07-07 |
2008-09-10 |
Neurocrine Biosciences, Inc. |
Pyrimidine-2,4-dione derivatives as gonadotropin-releasing hormone receptor antagonists
|
ATE557007T1
(de)
*
|
2003-07-07 |
2012-05-15 |
Neurocrine Biosciences Inc |
Arylpyrimidine geeignet zur behandlung von sexualhormonbedingten zuständen wie endometriose, prostatakrebs und dergleichen
|
US6995183B2
(en)
*
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7470700B2
(en)
|
2003-08-13 |
2008-12-30 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
WO2005019168A2
(en)
*
|
2003-08-20 |
2005-03-03 |
Pfizer Products Inc. |
Fluorinated lysine derivatives as dipeptidyl peptidase iv inhibitors
|
JP2007505121A
(ja)
|
2003-09-08 |
2007-03-08 |
武田薬品工業株式会社 |
ジペプチジルぺプチダーゼ阻害剤
|
WO2005030751A2
(en)
|
2003-09-08 |
2005-04-07 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
US7238107B2
(en)
|
2003-09-29 |
2007-07-03 |
Mcvay Iii Julian Clyde |
Consonant pain
|
CA2554809C
(en)
*
|
2004-02-05 |
2014-04-29 |
Probiodrug Ag |
Novel n-alkyl thiourea- and thioamide-substituted imidazolyl inhibitors of glutaminyl cyclase
|
AU2004318013B8
(en)
|
2004-03-15 |
2011-10-06 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
DE602005022319D1
(de)
*
|
2004-07-02 |
2010-08-26 |
Corcept Therapeutics Inc |
Modifizierte pyrimidin-glucocorticoid-rezeptor-modulatoren
|
JP2008524331A
(ja)
|
2004-12-21 |
2008-07-10 |
武田薬品工業株式会社 |
ジペプチジルペプチダーゼ阻害剤
|
CA2622472C
(en)
|
2005-09-14 |
2013-11-19 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors for treating diabetes
|
US20070060528A1
(en)
|
2005-09-14 |
2007-03-15 |
Christopher Ronald J |
Administration of dipeptidyl peptidase inhibitors
|
TW200745079A
(en)
|
2005-09-16 |
2007-12-16 |
Takeda Pharmaceuticals Co |
Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
|