BRPI0807453B8 - preparação sólida - Google Patents

preparação sólida

Info

Publication number
BRPI0807453B8
BRPI0807453B8 BRPI0807453A BRPI0807453A BRPI0807453B8 BR PI0807453 B8 BRPI0807453 B8 BR PI0807453B8 BR PI0807453 A BRPI0807453 A BR PI0807453A BR PI0807453 A BRPI0807453 A BR PI0807453A BR PI0807453 B8 BRPI0807453 B8 BR PI0807453B8
Authority
BR
Brazil
Prior art keywords
solid preparation
sugar
excipient
salt
pioglitazone
Prior art date
Application number
BRPI0807453A
Other languages
English (en)
Inventor
Nomura Junya
Kiyoshima Kenichiro
Nakamura Kenji
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39240362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0807453(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of BRPI0807453A2 publication Critical patent/BRPI0807453A2/pt
Publication of BRPI0807453B1 publication Critical patent/BRPI0807453B1/pt
Publication of BRPI0807453B8 publication Critical patent/BRPI0807453B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

preparação sólida uma preparação sólida contendo o composto (i), em que a definição do composto (i)é como definido no relatório descritivo, e pioglitazona, que é útil como um medicamento terapêutico para diabete e outros e superior na propriedade de dissolução, estabilidade química e estabilidade de dissolução, é fornecida. uma preparação sólida contendo as seguintes primeira e segunda partes: (1) a primeira parte contendo composto (i) ou um sal deste e, como o primeiro excipiente, açúcar ou álcool de açúcares; e (2) a segunda parte contendo pioglitazona ou um sal deste e, como o segundo excipiente, açúcar ou álcool de açúcares; e (2) a segunda parte contendo pioglitazona ou um sal deste e, como o segundo excipiente, açúcar ou álcool de açúcares.
BRPI0807453A 2007-02-01 2008-01-30 preparação sólida BRPI0807453B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007023594 2007-02-01
JP2007-023594 2007-02-01
PCT/JP2008/051900 WO2008093882A1 (en) 2007-02-01 2008-01-30 Solid preparation comprising alogliptin and pioglitazone

Publications (3)

Publication Number Publication Date
BRPI0807453A2 BRPI0807453A2 (pt) 2014-05-20
BRPI0807453B1 BRPI0807453B1 (pt) 2021-01-05
BRPI0807453B8 true BRPI0807453B8 (pt) 2021-05-25

Family

ID=39240362

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0807453A BRPI0807453B8 (pt) 2007-02-01 2008-01-30 preparação sólida

Country Status (39)

Country Link
US (1) US8637079B2 (pt)
EP (1) EP2107905B1 (pt)
JP (1) JP5284968B2 (pt)
KR (1) KR101486091B1 (pt)
CN (1) CN101646420B (pt)
AR (1) AR065097A1 (pt)
AT (1) ATE488227T1 (pt)
AU (1) AU2008211981B2 (pt)
BR (1) BRPI0807453B8 (pt)
CA (1) CA2677201C (pt)
CL (1) CL2008000279A1 (pt)
CR (1) CR10992A (pt)
CY (1) CY1111264T1 (pt)
DE (1) DE602008003522D1 (pt)
DK (1) DK2107905T3 (pt)
DO (1) DOP2009000195A (pt)
EA (1) EA015180B1 (pt)
EC (1) ECSP099608A (pt)
ES (1) ES2354397T3 (pt)
GE (1) GEP20125410B (pt)
HK (1) HK1138188A1 (pt)
HR (1) HRP20110094T8 (pt)
IL (1) IL200108A (pt)
JO (1) JO2650B1 (pt)
MA (1) MA31169B1 (pt)
ME (1) ME01239B (pt)
MX (1) MX2009008100A (pt)
MY (1) MY147596A (pt)
NZ (1) NZ579008A (pt)
PE (1) PE20081663A1 (pt)
PL (1) PL2107905T3 (pt)
PT (1) PT2107905E (pt)
RS (1) RS51592B (pt)
SI (1) SI2107905T1 (pt)
TN (1) TN2009000317A1 (pt)
TW (2) TWI453041B (pt)
UA (1) UA95828C2 (pt)
WO (1) WO2008093882A1 (pt)
ZA (1) ZA200905621B (pt)

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Also Published As

Publication number Publication date
DK2107905T3 (da) 2011-01-31
JP2010517937A (ja) 2010-05-27
CN101646420B (zh) 2012-11-07
EP2107905B1 (en) 2010-11-17
ME01239B (me) 2013-06-20
US20100092551A1 (en) 2010-04-15
CN101646420A (zh) 2010-02-10
CA2677201A1 (en) 2008-08-07
PL2107905T3 (pl) 2011-04-29
GEP20125410B (en) 2012-02-27
JO2650B1 (en) 2012-06-17
BRPI0807453A2 (pt) 2014-05-20
IL200108A0 (en) 2010-04-15
ES2354397T3 (es) 2011-03-14
RS51592B (en) 2011-08-31
WO2008093882A1 (en) 2008-08-07
PE20081663A1 (es) 2008-12-25
AR065097A1 (es) 2009-05-13
JP5284968B2 (ja) 2013-09-11
MA31169B1 (fr) 2010-02-01
CA2677201C (en) 2015-11-17
ATE488227T1 (de) 2010-12-15
CR10992A (es) 2009-09-16
MY147596A (en) 2012-12-31
EP2107905A1 (en) 2009-10-14
EA200970726A1 (ru) 2010-02-26
HRP20110094T8 (en) 2011-07-31
IL200108A (en) 2012-02-29
KR101486091B1 (ko) 2015-01-23
HK1138188A1 (en) 2010-08-20
TN2009000317A1 (en) 2010-12-31
AU2008211981B2 (en) 2012-09-20
PT2107905E (pt) 2010-12-17
SI2107905T1 (sl) 2011-03-31
US8637079B2 (en) 2014-01-28
NZ579008A (en) 2012-02-24
TWI453041B (zh) 2014-09-21
KR20090109115A (ko) 2009-10-19
ZA200905621B (en) 2010-10-27
BRPI0807453B1 (pt) 2021-01-05
DOP2009000195A (es) 2009-08-31
TW200836775A (en) 2008-09-16
AU2008211981A1 (en) 2008-08-07
CL2008000279A1 (es) 2008-08-18
ECSP099608A (es) 2009-09-29
EA015180B1 (ru) 2011-06-30
TW201350143A (zh) 2013-12-16
MX2009008100A (es) 2009-08-07
HRP20110094T1 (hr) 2011-03-31
UA95828C2 (ru) 2011-09-12
DE602008003522D1 (de) 2010-12-30
CY1111264T1 (el) 2015-08-05

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