BRPI0916069B8 - composto, usos de um composto e composição farmacêutica - Google Patents

composto, usos de um composto e composição farmacêutica Download PDF

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Publication number
BRPI0916069B8
BRPI0916069B8 BRPI0916069A BRPI0916069A BRPI0916069B8 BR PI0916069 B8 BRPI0916069 B8 BR PI0916069B8 BR PI0916069 A BRPI0916069 A BR PI0916069A BR PI0916069 A BRPI0916069 A BR PI0916069A BR PI0916069 B8 BRPI0916069 B8 BR PI0916069B8
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BR
Brazil
Prior art keywords
compound
pharmaceutical composition
pharmaceutical
oxoazetine
preparing
Prior art date
Application number
BRPI0916069A
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English (en)
Inventor
Bouix-Peter Claire
Suzuki Itaru
Pascal Jean-Claude
Rodeville Nicolas
Mauvais Pascale
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Galderma Res & Dev
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Application filed by Galderma Res & Dev filed Critical Galderma Res & Dev
Publication of BRPI0916069A2 publication Critical patent/BRPI0916069A2/pt
Publication of BRPI0916069B1 publication Critical patent/BRPI0916069B1/pt
Publication of BRPI0916069B8 publication Critical patent/BRPI0916069B8/pt
Publication of BRPI0916069C1 publication Critical patent/BRPI0916069C1/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/10—Preparations for permanently dyeing the hair
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract

composto, usos de um composto, e composição farmacêutica a presente invenção trata de novos compostos derivados de oxoazetina que correspondem à fórmula geral (i), das composições que os contêm, do processo para prepará-los e de seu uso em composições farmacêuticas ou cosméticas.
BRPI0916069A 2008-11-04 2009-11-04 composto, usos de um composto, composição farmacêutica, composição cosmética e usos cosméticos de uma composição BRPI0916069C1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11113008P 2008-11-04 2008-11-04
FR0857496A FR2937972B1 (fr) 2008-11-04 2008-11-04 Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
PCT/EP2009/064646 WO2010052253A1 (en) 2008-11-04 2009-11-04 Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics

Publications (4)

Publication Number Publication Date
BRPI0916069A2 BRPI0916069A2 (pt) 2015-11-10
BRPI0916069B1 BRPI0916069B1 (pt) 2019-11-05
BRPI0916069B8 true BRPI0916069B8 (pt) 2019-12-17
BRPI0916069C1 BRPI0916069C1 (pt) 2021-05-25

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BRPI0916069A BRPI0916069C1 (pt) 2008-11-04 2009-11-04 composto, usos de um composto, composição farmacêutica, composição cosmética e usos cosméticos de uma composição

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US (2) US8871187B2 (pt)
EP (1) EP2342194B1 (pt)
JP (1) JP5798486B2 (pt)
KR (1) KR101689042B1 (pt)
CN (2) CN102203081A (pt)
AR (1) AR074275A1 (pt)
AU (1) AU2009312818B2 (pt)
BR (1) BRPI0916069C1 (pt)
CA (1) CA2738785C (pt)
FR (1) FR2937972B1 (pt)
MX (1) MX2011004068A (pt)
RU (2) RU2671189C1 (pt)
WO (1) WO2010052253A1 (pt)

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FR2939135B1 (fr) * 2008-12-02 2010-12-03 Galderma Res & Dev Nouveaux composes 4-(azacycloalkyl)-benzene-1,3-diol comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
FR2969494B1 (fr) * 2010-12-22 2013-11-08 Expanscience Lab Extrait de parties aeriennes de gynandropsis gynandra ou cleome gynandra et compositions cosmetiques, dermatologiques le comprenant
FR2981933B1 (fr) * 2011-11-02 2013-11-15 Galderma Res & Dev Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
FR2984167B1 (fr) * 2011-12-16 2014-01-17 Galderma Res & Dev Association d'un agoniste des recepteurs des prostaglandines et d'un agoniste du recepteur mc1r pour le traitement et/ou la prevention de desordres de la pigmentation
WO2013135880A1 (en) 2012-03-15 2013-09-19 Galderma Research & Development Combination of a mc1r receptor agonist and uvb for the treatment and/or prevention of pigmentation disorders
FR2992317B1 (fr) 2012-06-22 2016-05-13 Diverchim Procede de preparation de peptides chiraux
FR3027900B1 (fr) 2014-11-05 2018-02-23 Centre National De La Recherche Scientifique Utilisation de derives halogenes de l'histidine a titre de sel d'electrolyte dans une cellule photovoltaique a colorants
CA2968836A1 (en) 2016-06-13 2017-12-13 Gilead Sciences, Inc. Fxr (nr1h4) modulating compounds
WO2018142318A1 (en) * 2017-02-01 2018-08-09 Clinuvel Pharmaceuticals Ltd Alpha-msh analogues used in the treatment of xeroderma pigmentosum
US20180280394A1 (en) 2017-03-28 2018-10-04 Gilead Sciences, Inc. Methods of treating liver disease
CA3129949C (en) 2019-02-19 2024-04-30 Gilead Sciences, Inc. Solid forms of fxr agonists
MX2023002974A (es) 2020-09-14 2023-05-25 Regeneron Pharma Conjugados de anticuerpo-farmaco que comprenden peptidomimeticos glp1 y usos de los mismos.
US20230330254A1 (en) 2022-03-11 2023-10-19 Regeneron Pharmaceuticals, Inc. Anti-glp1r antibody-tethered drug conjugates comprising glp1 peptidomimetics and uses thereof

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MY128261A (en) * 1992-10-27 2007-01-31 Merck Sharp & Dohme New substituted azetidinones as anti-inflammatory and antidegenerative agents
US6720001B2 (en) 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients
US6399651B1 (en) 2000-06-29 2002-06-04 L. Dean Parks Method of treating dermatoses using avermectin compound
CA2439691A1 (en) * 2001-03-02 2002-09-12 Bristol-Myers Squibb Company Co-administration of melanocortin receptor agonist and phosphodiesterase inhibitor for treatment of cyclic-amp associated disorders
JP2004532838A (ja) * 2001-03-02 2004-10-28 ブリストル−マイヤーズ スクイブ カンパニー メラノコルチン受容体のモデュレーターとして有用な化合物及びそれを含む製薬組成物
US6977264B2 (en) * 2001-07-25 2005-12-20 Amgen Inc. Substituted piperidines and methods of use
KR100661118B1 (ko) * 2003-11-12 2006-12-26 주식회사 엘지생명과학 멜라노코틴 수용체의 항진제
WO2005047253A1 (en) * 2003-11-12 2005-05-26 Lg Life Sciences Ltd. Melanocortin receptor agonists
FR2867684B1 (fr) 2004-03-18 2006-05-05 Galderma Sa Gel creme contenant de l'ivermectine

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Publication number Publication date
US20150045559A1 (en) 2015-02-12
CN104387372A (zh) 2015-03-04
EP2342194B1 (en) 2018-08-08
BRPI0916069A2 (pt) 2015-11-10
RU2671189C1 (ru) 2018-10-30
EP2342194A1 (en) 2011-07-13
JP2012507491A (ja) 2012-03-29
CN104387372B (zh) 2018-06-26
KR101689042B1 (ko) 2016-12-22
WO2010052253A1 (en) 2010-05-14
BRPI0916069C1 (pt) 2021-05-25
JP5798486B2 (ja) 2015-10-21
CN102203081A (zh) 2011-09-28
RU2569886C2 (ru) 2015-12-10
US8871187B2 (en) 2014-10-28
BRPI0916069B1 (pt) 2019-11-05
US9630949B2 (en) 2017-04-25
AR074275A1 (es) 2011-01-05
FR2937972B1 (fr) 2013-03-29
US20110274638A1 (en) 2011-11-10
CA2738785A1 (en) 2010-05-14
RU2011122637A (ru) 2012-12-20
CA2738785C (en) 2017-05-16
KR20110088555A (ko) 2011-08-03
AU2009312818A1 (en) 2010-05-14
FR2937972A1 (fr) 2010-05-07
AU2009312818B2 (en) 2014-11-06
MX2011004068A (es) 2011-05-31

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