FR2992317B1 - Procede de preparation de peptides chiraux - Google Patents

Procede de preparation de peptides chiraux

Info

Publication number
FR2992317B1
FR2992317B1 FR1255932A FR1255932A FR2992317B1 FR 2992317 B1 FR2992317 B1 FR 2992317B1 FR 1255932 A FR1255932 A FR 1255932A FR 1255932 A FR1255932 A FR 1255932A FR 2992317 B1 FR2992317 B1 FR 2992317B1
Authority
FR
France
Prior art keywords
preparation
chiral
peptides
chiral peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1255932A
Other languages
English (en)
Other versions
FR2992317A1 (fr
Inventor
Jean-Louis Brayer
Benoit Folleas
Laetitia Palais
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diverchim SA
Original Assignee
Diverchim SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diverchim SA filed Critical Diverchim SA
Priority to FR1255932A priority Critical patent/FR2992317B1/fr
Priority to PCT/FR2013/051327 priority patent/WO2013190212A1/fr
Publication of FR2992317A1 publication Critical patent/FR2992317A1/fr
Application granted granted Critical
Publication of FR2992317B1 publication Critical patent/FR2992317B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
FR1255932A 2012-06-22 2012-06-22 Procede de preparation de peptides chiraux Active FR2992317B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1255932A FR2992317B1 (fr) 2012-06-22 2012-06-22 Procede de preparation de peptides chiraux
PCT/FR2013/051327 WO2013190212A1 (fr) 2012-06-22 2013-06-07 Procede de preparation de peptides chiraux

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1255932A FR2992317B1 (fr) 2012-06-22 2012-06-22 Procede de preparation de peptides chiraux

Publications (2)

Publication Number Publication Date
FR2992317A1 FR2992317A1 (fr) 2013-12-27
FR2992317B1 true FR2992317B1 (fr) 2016-05-13

Family

ID=47022780

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1255932A Active FR2992317B1 (fr) 2012-06-22 2012-06-22 Procede de preparation de peptides chiraux

Country Status (2)

Country Link
FR (1) FR2992317B1 (fr)
WO (1) WO2013190212A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
US8802868B2 (en) 2010-03-25 2014-08-12 Vertex Pharmaceuticals Incorporated Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
KR101984225B1 (ko) 2010-04-22 2019-05-30 버텍스 파마슈티칼스 인코포레이티드 시클로알킬카르복스아미도-인돌 화합물의 제조 방법
PT3925607T (pt) 2014-04-15 2023-09-26 Vertex Pharma Composições farmacêuticas para o tratamento de doenças mediadas pelo regulador de condutância transmembranar da fibrose quística
US10774064B2 (en) 2016-06-02 2020-09-15 Cadent Therapeutics, Inc. Potassium channel modulators
AR110770A1 (es) 2017-01-23 2019-05-02 Cadent Therapeutics Inc Moduladores del canal de potasio
CN108341757B (zh) * 2017-01-25 2022-02-08 中国科学院上海药物研究所 手性氨基酸酯类化合物及制备方法和用途
SG11202001684PA (en) 2017-10-06 2020-03-30 Forma Therapeutics Inc Inhibiting ubiquitin specific peptidase 30
JP7337174B2 (ja) 2018-09-18 2023-09-01 ニカング セラピューティクス， インコーポレイテッド Ｓｒｃホモロジー－２ホスファターゼ阻害剤としての三置換ヘテロアリール誘導体
WO2020072964A1 (fr) 2018-10-05 2020-04-09 Forma Therapeutics, Inc. Pyrrolines fusionnées qui agissent en tant qu'inhibiteurs de la protéase 30 (usp30) spécifique de l'ubiquitine
AU2019366312A1 (en) 2018-10-22 2021-05-20 Novartis Ag Crystalline forms of potassium channel modulators
CN114671729B (zh) * 2022-04-01 2023-04-25 南京大学 一种芳香乙胺及其衍生物的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1354571A (en) 1971-01-13 1974-06-05 Beecham Group Ltd Amides and their use as insecticides
US6693123B2 (en) 1995-11-06 2004-02-17 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
FR2830254B1 (fr) 2001-09-28 2004-09-17 Synkem Nouvelles diphosphines, leurs complexes avec des metaux de transition et leur utilisation en synthese asymetrique
US7105539B2 (en) 2002-12-03 2006-09-12 Enobia Pharma Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex
EA019033B1 (ru) 2008-03-26 2013-12-30 Новартис Аг Ингибиторы дезацетилазы в, основанные на гидроксамате
FR2937972B1 (fr) 2008-11-04 2013-03-29 Galderma Res & Dev Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
EP2316407B1 (fr) 2009-10-30 2021-04-28 Dentsply DeTrey GmbH Composition dentaire
FR2969604B1 (fr) * 2010-12-23 2013-01-18 Diverchim Procede de preparation d'acides amines chiraux

Also Published As

Publication number Publication date
WO2013190212A1 (fr) 2013-12-27
FR2992317A1 (fr) 2013-12-27

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